David J. Cohen, MD, MSc @djc795 Twitter profile

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@jizzaso

David J. Cohen, MD, MSc

@djc795

4 years

So, apparently, the statistics in the NEJM report on compassionate use remdesivir without a control group were wrong. 53 authors and not one knows how to conduct a Kaplan-Meier analysis??

Compassionate Use of Remdesivir in Covid-19 | NEJM

To the Editor: In their article, Grein et al. (published online on April 10 at NEJM.org)1 report outcomes in a cohort of patients who were hospitalized for severe Covid-19 and who received remdesiv...

www.nejm.org

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David J. Cohen, MD, MSc

@djc795

4 years

@NoopurRajeMD @JagSinghMD Thank you very much for sharing this experience. It is enormously helpful to hear the medical professional’s perspective— both clinical and personal. I am so glad to hear Jag is doing better- praying for continued steady recovery.

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David J. Cohen, MD, MSc

@djc795

3 years

@DGlaucomflecken As a cardiologist, I approve this video. And I'm definitely asking the mountain range question in the future.

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David J. Cohen, MD, MSc

@djc795

3 years

Next trial... DAPA-Breathing. Randomize anyone who is breathing to DAPA vs. placebo. I suspect it will show benefit.

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David J. Cohen, MD, MSc

@djc795

4 years

Just today, I have had DMs from several cardiologists in states with plenty of COVID-19 cases where they say that their partners are refusing to stop doing elective procedures— justifying them as “urgent”. This is nuts.

Jonathan Reiner

@JReinerMD

4 years

Sadly, for the docs still trying to schedule elective procedures, it’s not about the patients, it’s about the money.

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David J. Cohen, MD, MSc

@djc795

4 years

Italy COVID-19 Update (Day #3 )-- continued good news with slowing of the growth rate for both cases and mortality.

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David J. Cohen, MD, MSc

@djc795

4 years

@PrakritiGaba Thank you for sharing this. All of us are with you in spirit and appreciate the tremendous effort despite the emotional strain. You are all heroes.

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David J. Cohen, MD, MSc

@djc795

4 years

@VPrasadMDMPH Are you saying that hydroxychloroquine is not one of the steps in the Krebs cycle?

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David J. Cohen, MD, MSc

@djc795

4 years

Although Italy had its worst day to date (6557 new cases, 793 deaths), in the "silver lining" department, it’s clear that COVID-19 cases and deaths are not growing exponentially in Italy anymore.

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David J. Cohen, MD, MSc

@djc795

2 years

1/n- Congratulations to my brother, Josh Cohen, who successfully ran the Boston Marathon twice today (yes, you read that correctly). This morning he ran the official marathon, finishing in 3:25. And then he got in a van, went back to the starting line, and ran it again...

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David J. Cohen, MD, MSc

@djc795

2 years

@Uqayyum123 @DavidLBrownMD @drjohnm @PraveenRangana9 @RonBlankstein @khurramn1 @RFRedberg @BudoffMd @MichaelJBlaha @dmljmd @cardio10s @pnatarajanmd @lesleejshaw @EricWillMD @ToddVillinesMD @AChoiHeart @dramitkhera @KBibbinsDomingo @ErinMichos A few years ago, someone explained to me that the goal on Twitter isn't to convince the person you are arguing with (which is almost always impossible). It's to convince everyone else.

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David J. Cohen, MD, MSc

@djc795

4 years

Italy COVID-19 Update (Day 5) Sorry I'm late with this today- had to go grocery shopping for flour and kosher salt for my daughter (who is an amazing cook!). Growth rates continue to ↓ for both death and cases.

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David J. Cohen, MD, MSc

@djc795

4 years

My first ever tweetorial! In the last 48 hours, there has been a lot of buzz in the lay press (WSJ, CNN) about a new observational study of hydroxychloroquine (HCQ) in COVID-19 ().

Treatment with hydroxychloroquine, azithromycin, and combination in patients hospitalized with...

As of May 27, 2020, there were over 1,678,843 confirmed cases of COVID-19 claiming more than 100,000 lives in the Unites States (CDC, 2020). Currently there is no known effective therapy or vaccine....

www.ijidonline.com

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David J. Cohen, MD, MSc

@djc795

2 years

@CMichaelGibson IMHO (and experience), burnout of physicians is almost always due to loss of control of one's professional life (whether real or perceived). Most physicians enjoy working hard, but they want to feel like they have some say over what they do and when they do it.

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David J. Cohen, MD, MSc

@djc795

1 year

This sign caught my eye at my local grocery store on the Upper West Side today- only in America. 😂😂😂

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David J. Cohen, MD, MSc

@djc795

3 years

Beautiful day for the marathon here in NYC. Waiting at the 25 mile mark for my brother, Josh, to run by.

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David J. Cohen, MD, MSc

@djc795

2 years

At Moynihan train hall in NYC— heading up to Boston for TCT in a few minutes. Looking forward to seeing friends and colleagues soon!

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David J. Cohen, MD, MSc

@djc795

2 years

1/x Mini-Tweetorial on External Validity vs. Competing Risk. Based on an ongoing discussion with @drjohnm , @ATSandhu , @gcfmd , @mikejohansenmd and others, I have put together this mini-tweetorial on how to think about external validity of trials vs. competing risks.

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David J. Cohen, MD, MSc

@djc795

2 years

@DFCapodanno @sbrugaletta @PCRonline @TCTMD @mirvatalasnag @mmamas1973 @alaide_chief @HolgerNef @thiele_holger @GreggWStone @secardiologia @EAPCIPresident @Ortega_Paz @nickaram @NEJM When I was a fellow, I had a poster presentation at AHA, which was published as the lead article in NEJM the following week. :)

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David J. Cohen, MD, MSc

@djc795

8 months

@vass_vassiliou @mmamas1973 @SVRaoMD @Simoneccles66 @tomkaier @Hragy @ShrillaB @aayshacader @ALadwiniec @cardiacpolymath I think Werner Forssmann already won a Nobel prize for that.

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David J. Cohen, MD, MSc

@djc795

2 months

On my train heading to #CRT2024 . Bagel and coffee in hand. Looking forward to seeing old friends and meeting new ones!

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David J. Cohen, MD, MSc

@djc795

6 months

Nice summary of a landmark trial proving once and for all that PCi does relieve angina beyond the placebo effect. I agree with comments by @rwyeh that this study is not intended to inform practice so much as to answer a fundamental mechanistic and physiological question…

Michael O'Riordan

@michaelTCTMD

6 months

Placebo-Controlled ORBITA-2 Shows PCI Eases Symptoms in Stable Angina

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David J. Cohen, MD, MSc

@djc795

3 years

Congratulations to my daughter, @emily_ann_cohen , who just published her first Op-Ed in a major US newspaper! I'm so proud of you, Emily. #Proudpapa @bowdoinorient @Fulbright_AUT @crfheart @MidAmericaHeart @SmithBIDMC

The Kansas City Star

@KCStar

3 years

Jewish Pembroke grad: Why are parents more worried about retaliation than swastika?

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David J. Cohen, MD, MSc

@djc795

4 years

@AnastasiaSMihai Hard to believe. For some reason, they decided to censor patients who died in an analysis that was looking at time to improvement. Unfortunately, this is what happens when publications are rushed.

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David J. Cohen, MD, MSc

@djc795

4 years

Updated spreadsheet and graphs from Italy with data from 3/22/20 (5561 new cases, 651 new deaths)-- trends continue to be promising. @CMichaelGibson @ajaykirtane

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David J. Cohen, MD, MSc

@djc795

3 months

Just finished a great day of Cardiology Grand Rounds at Stanford. It was fantastic to meet so many bright, inquisitive, and motivated @StanCVFellows . Thanks to @SnehaShahJain and @wfearonmd for inviting me and making me feel at home!

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David J. Cohen, MD, MSc

@djc795

7 months

White sneaker day— Twins!! #TCT2023 @mbmcentegart

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David J. Cohen, MD, MSc

@djc795

4 years

Italy COVID-19 Update (Day 10) I took the weekend off to recharge, so today's charts and graphs include the last 3 days. Case incidence trends are definitely starting to improve. It may be a while for deaths to catch up, though. Stay safe, everyone! @CMichaelGibson @ajaykirtane

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David J. Cohen, MD, MSc

@djc795

3 years

@ashishkjha Very well explained. Reminiscent of the seminal studies of Medicare admission rates for New Haven vs. Boston by Wennberg and colleagues nearly 30 years ago. Threshold for hospital admission varies with capacity--> supply drives utilization (rather than just demand).

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David J. Cohen, MD, MSc

@djc795

8 months

@baijazvascular @SrihariNaiduMD @SVRaoMD @SCAI @ACCinTouch @DrJMarine @SandeepNathanMD @Radial_ICG @MortonKern @yuripridemd Spiral prox. RCA dissection is far more common in pts with normal coronary arteries (like this one), because there is nothing to keep the dissection from propagating. This is a good reason to favor CTA as the initial diagnostic test in pts with low prior probability of CAD.

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David J. Cohen, MD, MSc

@djc795

4 years

Let me add my voice to so many others in thanking the #cardiotwitter community for their teaching, passion, education, inspiration, and most importantly, friendship this past year. Happy Thanksgiving to all!

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David J. Cohen, MD, MSc

@djc795

4 years

Italy COVID-19 Update (Day 13) Trends continue to look favorable in Italy. Let's hope this is what things are starting to look like in the US in 2 weeks or so (since Italy is about 10 days ahead of us). @CMichaelGibson @ajaykirtane

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David J. Cohen, MD, MSc

@djc795

3 years

Academic cardiologists: We jumped out of a stationary plane at 4 feet to make a fun point about how selection bias can affect even an RCT. This guy: Hold my beer. @rwyeh @bnallamo

LADbible

@ladbible

3 years

What the actual f**k?!? Luke Aikins here casually breaking the world record by jumping from 7620 meters without a parachute. Some serious minerals.

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David J. Cohen, MD, MSc

@djc795

3 years

@turilrh @mirvatalasnag @mmamas1973 @akbarul @evandrofilhobr @aksyksvsclb Some cases are silly to consider PCI— and this is one of them. I wouldn’t even offer it. I would say (as I often do), “no one WANTS a CABG, but some people NEED one. And you need a CABG.”

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David J. Cohen, MD, MSc

@djc795

5 years

Congratulations to Suzanne Baron, MD MSc and the amazing health economics research group at @MidAmericaHeart who conducted this ground-breaking study! #TAVR is truly a revolutionary procedure.

Circulation

@CircAHA

5 years

Is #TAVR vs #SAVR more cost-effective in intermediate risk pts? @djc795 @saintlukeskc analysis of PARTNER 2 trial finds TAVR is projected to be economically dominant. Read more:

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David J. Cohen, MD, MSc

@djc795

4 years

Congratulations to my long-time partner, colleague, and friend @jspertus for leading the QOL component of the ISCHEMIA trial and for showing the true value of coronary revascularization to our patients. Great culmination to a lifetime of work.

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David J. Cohen, MD, MSc

@djc795

1 year

@Radial_ICG I would argue that no IC is fully trained until the sh*t hits the fan in the middle of the night when no one else is around. And no volume of cases done with the attending watching from the control room is adequate training for that moment.

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David J. Cohen, MD, MSc

@djc795

4 years

@FredWuMD Make sure to remove all the double spaces after period before sacrificing those Oxford commas. Also, semicolons are only half a character; use them liberally. :)

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David J. Cohen, MD, MSc

@djc795

4 years

Very useful information. Based on some anecdotes from the US and Italy, I wonder how much of this excess all-cause mortality is “unreported COVID” and how much is “collateral damage” among patients without COVID (e.g., waiting out a STEMI at home).

Giuseppe Biondi-Zoccai

@gbiondizoccai

4 years

Still we miss the elephant in the room... all-cause deaths... just look at what happened in Northern Italy... this discrepancy between official COVID-19 deaths and true COVID-19 burden in mortality is the most likely explanation of the way too rosy situation in China

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David J. Cohen, MD, MSc

@djc795

2 years

3/n- Here's a photo of him 4 years ago taking part in the World Marathon Challenge in which he ran 7 marathons in 7 days on 7 continents. If you can't tell, the photo is of the marathon he ran in Antartica.

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David J. Cohen, MD, MSc

@djc795

3 years

Speaking of publishing, I am super-proud of my daughter, @emily_ann_cohen , who just published her first article as a professional freelance writer (is that a thing?) in @hey_alma . #proudpapa .

'The O.C.' Is a Surprisingly Nuanced Portrayal of a Jewish Family

I was too young to watch “The O.C.” when it first came out. Back in the summer of 2003, I was 5, glued to such Disney classics as “Lizzie McGuire” and “The Cheetah Girls.” I knew references to the...

www.heyalma.com

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David J. Cohen, MD, MSc

@djc795

11 months

Outstanding work by @rwyeh and team from @SmithBIDMC to examine the benefit of #Impella in AMI/CS. If you are still confused after reading the paper, check out the editorial by @manesh_patelMD and yours truly for additional explanation and some key lessons (link below)

BIDMC Smith Center

@SmithBIDMC

11 months

Investigators from @SmithBIDMC worked with @US_FDA investigators to apply state-of-the-science methods to examine the impact of Impella on outcomes in myocardial infarction patients with shock. The conclusions might surprise you.

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David J. Cohen, MD, MSc

@djc795

1 year

@drjohnm I have said this before— I agree with many others that the vast swath of level 2 guidelines and expert opinion are not worth the writing nor the reading. Tell us what we ought to do (level 1) and what we ought not to do (level 3), and that’s plenty.

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David J. Cohen, MD, MSc

@djc795

4 years

So this just happened-- a whole op-ed in todays @nytimes on Bayes' Theorem. Who had May 13, 2020 in the office pool? @venkmurthy @rwyeh @CMichaelGibson

Opinion | Just Because You Test Positive for Antibodies Doesn’t Mean You Have Them (Published 2020)

In a population whose infection rate is 5 percent, a test that is 90 percent accurate could deliver a false positive nearly 70 percent of the time.

www.nytimes.com

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David J. Cohen, MD, MSc

@djc795

4 years

@jedicath @ZLevyMD Hard to imagine that any single service could handle this crush. The Italian experience seemed to be that every service ended up having to take on these patients to make the workload tolerable.

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David J. Cohen, MD, MSc

@djc795

5 years

Congratulations to @SuzanneJBaron , my amazing mentee, colleague, structural cardiologist, and friend on her presentation and simultaneous publication on 2 LBCTs at TCT this morning. Credit also to my incredible team at @MidAmericaHeart who make us all look good.

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David J. Cohen, MD, MSc

@djc795

5 years

So proud of my daughter, @emily_ann_cohen , who just published her first edition of The Bowdoin Orient as editor-in-Chief! #proudpapa

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David J. Cohen, MD, MSc

@djc795

4 years

@ethanjweiss Someone posted this earlier today. It seems very apropos here...

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David J. Cohen, MD, MSc

@djc795

2 years

1/x- Observations from reviewing AHA Abstracts on Non-Coronary Cardiac Interventions-- a brief thread. Of 60 abstracts, 26 (43%) were either meta-analyses (n=9) or analyses of either the Nationwide Inpatient Sample (NIS, n=8) or National Readmissions Database (NRD, n=9)

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David J. Cohen, MD, MSc

@djc795

4 years

Italy COVID-19 Update (Day 7) Mortality trend is concerning, but as I mentioned yesterday, case trends (assuming consistent testing patterns) are more important than deaths in some ways, because deaths always lag. And rate of case growth shows continued slowing. (1/2)

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David J. Cohen, MD, MSc

@djc795

4 years

I am so proud of my daughter, @emily_ann_cohen , who has led her college newspaper, the Bowdoin Orient, through this difficult year with integrity, class, and an indomitable spirit. These photos document both the process and joy of the accomplishment. Emily, you are amazing!

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David J. Cohen, MD, MSc

@djc795

5 months

For those who want a balanced discussion of the WATCHMAN trials and why its approval by FDA might not be the craziest thing ever, read this nuanced thread by @AlbertLinMD1 on the challenges that we all face in balancing evidence and innovation in the CV device space.

Albert Lin, MD

@AlbertLinMD1

5 months

I hesitate to reply on Twitter where nuance goes to die, but, a few points on this thread by JM et al focusing in on Watchman as that's an area I feel comfortable with the data and history. Let's start with a few stipulations:

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David J. Cohen, MD, MSc

@djc795

10 months

@DrQuinnCapers4 IMHO, a first year fellow in week 1 will learn far more from careful observation than from the stress of trying to perform skills they haven’t come close to mastering. There is a time to let them start the case. This isn’t it.

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David J. Cohen, MD, MSc

@djc795

5 years

Congratulations to my colleague and mentee, Dr. Suzanne Baron, on having 2 LBCTs (yes, 2) selected for presentation at the upcoming TCT meeting in San Francisco! Please join us in the main arena on 9/29 to cheer her on. You won’t be disappointed!

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David J. Cohen, MD, MSc

@djc795

10 months

@georgetolisjr You must have missed this one. No survival benefit...

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David J. Cohen, MD, MSc

@djc795

11 months

@oqabdoc @mmamas1973 @rajivxgulati @minhaskh @KPujdak @NosairMohamed @mandeep_mayo @jbbreau @ld_maude @Umair2017 Pain is not the indication for PCI in SCAD as it often is coming from the dissection rather than from ongoing ischemia. I would need to have clearcut evidence of ongoing ischemia (e.g., TIMI flow <3, ongoing ST elevation, hemodynamic instability) to push me to PCI.

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David J. Cohen, MD, MSc

@djc795

3 years

@DrSaritaRao2 @mmamas1973 @stefan_harb @CMichaelGibson @aayshacader @ShrillaB @CardioNerds @AdityaMandawat @PCRonline @RameshDaggubati @evandrofilhobr @EuroInterventio Here are the 2 cardinal rules of IC, courtesy of Don Baim: (1) Do not treat a vessel you can't name; (2) Do not perform a procedure if you can't manage the complications yourself (shy of needing surgery). @jjlop131 @duanepinto @ajaykirtane @CMichaelGibson @SVRaoMD @Stent4U

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David J. Cohen, MD, MSc

@djc795

2 years

@AshleyGWinter @emily_fri Primary PCI for STEMI. Life saving and gratifying— not a bad combination.

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David J. Cohen, MD, MSc

@djc795

3 months

@GoldbergJBCTMD @ehj_ed @ESC_Journals @escardio @BoYangMD @drandrewsharp @STS_CTsurgery @AATSHQ @DrMoritzWvB And the real irony is that we all spent the last 10 years worrying about TAVR durability, but the problem ended up being certain widely used surgical valves that never underwent rigorous clinical trials.

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David J. Cohen, MD, MSc

@djc795

3 years

Congratulations, Mayra-- 3 separate first author publications in a single issue of JACC Interventions is an amazing accomplishment! Thank you for your tremendous leadership in this field.

Mayra Guerrero, MD

@MayraGuerreroMD

3 years

MITRAL Trial MAC Arm: Pts treated with TS ViMAC had 6.7% 30-day mortality, was lower than predicted by the STS score (mean 9.9%, median 6.2%). At 1 year, ViMAC was associated with improved symptoms & stable THV performance. @MayoClinicCV @JACCJournals

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David J. Cohen, MD, MSc

@djc795

4 years

@mirvatalasnag @venkmurthy As I learned from @duanepinto , the most aggressive cardiologist is your non-invasive partner who is on call for the weekend.

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David J. Cohen, MD, MSc

@djc795

3 years

@CMichaelGibson JAMA Network Open-- "Let's charge $3000 per article" JAMA Health-- "Hold my beer"

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David J. Cohen, MD, MSc

@djc795

1 year

@vbluml @robmentz @dranulala @ShelleyZieroth @manreetkanwar @coconnormd @RyanTedfordMD @JJheart_doc @MKIttlesonMD @rcstarling @DukeHFDoc @SvatiShah @ersied727 @AndrewJSauer @ShashankSinhaMD @NavinKapur4 @SJGreene_md @mvaduganathan @FaRodriguezMD @AnnMarieNavar @JasonKatzMD @noshreza @MaryjaneFarrMD Get as much methodologic training as possible during fellowship or sooner. This is important "currency" that you will carry with you for the rest of your life and will be much harder to carve out time for once you are on faculty.

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David J. Cohen, MD, MSc

@djc795

1 year

This was truly an inspiring talk of the true origins of TAVR. Don’t often see a standing ovation at SCAI. For those who haven’t heard Dr. Andersen speak, I hope you get the opportunity.

Wally A. Omar, MD

@WallyOmarMD

1 year

An honor to listen to Dr. Henning Andersen discuss the journey of #TAVR , from an idea he had 34 years ago with hardware store wires and a butcher-shop pig ❤️, to what it is today. Never give up on your vision! #SCAI2023

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David J. Cohen, MD, MSc

@djc795

2 years

Sunset over the Hudson River— from Peekskill, NY. Who knew this was just 30 miles north of NYC?

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David J. Cohen, MD, MSc

@djc795

3 years

Fascinating description of the introduction (via Twitter) of the Impella single-access technique and its rapid dissemination in interventional practice via social media. See poll below.

Image in cardiology: IMPELLA supported PCI via a single access sheath introduction and rapid...

This manuscript examines Impella single access technique, which provides a case example of the central role social media can play in the introduction of a new interventional approach.

www.pcronline.com

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David J. Cohen, MD, MSc

@djc795

9 months

Congratulations to my friend and colleague, @ziadalinyc , on leading the ILLUMIEN-IV trial— a truly monumental trial and one that will be providing critical insights for the IC community for years to come. @OPCILive @DrAllenJ @ESHLOF

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David J. Cohen, MD, MSc

@djc795

1 year

@rahatheart1 @rafasadaba @ovidiogarciav @Almanfi_Cardio @Coronary4front @FaisalBakaeen @mirvatalasnag @SukhNijjer I enjoy a good observational study as much as anyone, but this is not one of those. Even without reading the full paper, I can see 2 obvious signs that this study is hopelessly confounded based on the original tweet. Challenge to the #CardioTwitter community to find the 2 clues.

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David J. Cohen, MD, MSc

@djc795

4 months

@drjohnm If the fellow had written more abstracts, they wouldn’t have had time to do that extra cath. And this complication might well have been avoided. Who says research doesn’t save lives? 😊

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David J. Cohen, MD, MSc

@djc795

3 years

@drjohnm **self-confidence (although elf-confidence might be helpful, too).

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David J. Cohen, MD, MSc

@djc795

4 years

@manesh_patelMD @DukeHealth @camwolfe My conclusion is that the "COVID-19 authorship rule" remains in effect-- more authors (56) than patients (53 after excluding 8 patients with incomplete data).

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David J. Cohen, MD, MSc

@djc795

4 years

@drjohnm @ajaykirtane @rwyeh Yup. Which is 149 more patients than were enrolled in the randomized trials that demonstrated that aortic valve replacement surgery is the “gold standard” for anything.

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David J. Cohen, MD, MSc

@djc795

3 years

@drjohnm The key to humor in a public forum is the ability to laugh at oneself. But that takes a fair amount of introspection and elf-confidence, both of which seem to be in relatively short supply.

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David J. Cohen, MD, MSc

@djc795

5 years

@MKIttlesonMD This has to be a fictitious case— I’ve never seen a neurologist provide such a clear prognosis. :)

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David J. Cohen, MD, MSc

@djc795

2 years

@mmamas1973 @drrashid05 @hwijeysundera @ncurzen @DrAsifQasim @rwyeh @SVRaoMD @GreggWStone @ShelleyWood2 @DavidLBrownMD @alaide_chief @ShrillaB @mirvatalasnag @cardiojaydoc02 @rallamee @ajaykirtane @amibanerjee1 @dr_mosama @Hragy @aymanka @aayshacader @agtruesdell @KardiologieHH @iamritu As noted, in the UK system, financial incentives don’t explain this pattern. I think the most likely explanation is that— at their core— most ICs don’t really believe the trial results.

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David J. Cohen, MD, MSc

@djc795

8 months

@drjohnm IMHO, metaanalysis of observational comparative effectiveness studies is one of the worst ideas in all of medical research. The process of metaanalysis completely obscures any understanding of the limitations of the individual studies, which are then amplified by pooling.

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David J. Cohen, MD, MSc

@djc795

2 years

@pomyers @BavariaMd I'm sure everyone knows this, but this indirect "comparison" would be bad enough if it were risk-adjusted (which it isn't). Without risk adjustment, it's completely worthless.

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David J. Cohen, MD, MSc

@djc795

4 years

Very proud of my daughter, Emily, and her co-editor for their dedication to keeping the oldest, continuously published college newspaper running strong despite the COVID epidemic. It was inspiring to watch her work into the early morning hours get the issue out. #proudpapa

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David J. Cohen, MD, MSc

@djc795

4 years

@saraceciliamtz In general, guides with side holes provide false reassurance as the guide can still be obstructive with a normal appearing “tip pressure”. Better to control guide position with forward pressure on the wire and back it out after each injection.

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David J. Cohen, MD, MSc

@djc795

4 years

I was going to tweet this study out, but I can’t do any better than @mmamas1973 . Thanks for highlighting our work! Shout out to @nmbutala , fellow extraordinaire from @MGHHeartHealth and @SmithBIDMC who really led the study and will be first author on the paper.

Mamas A. Mamas

@mmamas1973

4 years

1. @djc795 presenting a superb analysis from TVT registry studying EPD in #TAVR with primary endpoint CVA, a variety of 2ndry endpoints (see slides) and nice to see a falsification endpoint of GI/GU bleed @SVRaoMD @HeartOTXHeartMD @RodrigoBagur @omendiz @jgranadacrf #TCTConnect

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David J. Cohen, MD, MSc

@djc795

1 year

@georgetolisjr I think a lot of the problem is that academic programs see themselves as in the “research” biz rather than the “teaching” biz. Introspection would be a good place to start.

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David J. Cohen, MD, MSc

@djc795

4 years

@DavidDobiesMD @GilbertTangMD @pomyers @TCTMD @VictorDayan1 @igeorge1975 @tomcnguyen @TsuyoshiKaneko1 @OPreventzaMD @JessicaLuc1 @tnazifMD @mirvatalasnag @ZeroTLR No need to wait. Here's the Cliff's Notes version: 1. No meaningful diff in mortality through 5 or 10 years 2. Stroke risk slightly lower with PCI 3. Spontaneous MI reduced with CABG (1/2)

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David J. Cohen, MD, MSc

@djc795

4 years

@DavidLBrownMD This patient doesn’t need “preventative cardiology” What he does need is to be prevented from seeing a cardiologist. :)

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David J. Cohen, MD, MSc

@djc795

3 years

A recent publication suggests that the average starting salary for an IC is $611,000. I'm curious if this rings true. If you are a US-based IC and have started a new position in the last 5 years, what was your starting salary (excluding any bonuses or other perks)?

$250,000- $400,000

757

$400,000-$500,000

410

$500,000-$600,000

242

>$600,000

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David J. Cohen, MD, MSc

@djc795

3 years

@GiuseppeGalati_ @jhernandeznp @markcpetrie20 @JJheart_doc @ShelleyZieroth @DrNasrien @hvanspall @DrMarthaGulati @ValleAlfonso @KTamirisaMD @pumpinghearts @DrRajivsankar @SABOURETCardio @DBelardoMD Because I'm a cardiologist first. And in the US, general cardiologists (including ICs) treat the vast majority of HFpEF patients. Finally, much of my research is in QOL (including at least 50 papers published using the KCCQ), so I feel like I'm pretty qualified here.

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David J. Cohen, MD, MSc

@djc795

4 years

For those of us who spend far too much time trying to get manuscripts published, this is absolutely spectacular. Well done! @rwyeh @EricSecemskyMD @SVRaoMD @rkwadhera @DocStrom @MichaelNassifMD @jtsaxon @arnoldgehrke @bnallamo @ethanjweiss @JeremySussman

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David J. Cohen, MD, MSc

@djc795

7 months

Congratulations to ⁦ @arnoldgehrke ⁩ for her LBCT presentation at #TCT2023 – providing critical new insights into the QOL benefit of T-TEER. And kudos to ⁦ @SuzanneJBaron ⁩ for insightful comments. It has been a privilege to mentor both of these rockstars!!!

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David J. Cohen, MD, MSc

@djc795

4 years

@jtsaxon @DGlaucomflecken That's not always true. Some of us make it up based on the cath.

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David J. Cohen, MD, MSc

@djc795

2 years

2/n- this time as part of a group running with race director, Dave McGillivray, to check the course for any stragglers. Yes, he's a little crazy, but he's still my baby brother. #bostonmarathon2022

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David J. Cohen, MD, MSc

@djc795

3 years

@CMichaelGibson @drjohnm Abstracts especially are a total crapshoot. My first AHA abstract as a fellow was accepted only as a poster (in a time when there were lots of oral abstract sessions). It was published as the lead article in NEJM the following week.

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David J. Cohen, MD, MSc

@djc795

3 years

This seems like a practice-changing trial that is likely to be highly disruptive to care paradigms for OOH cardiac arrest. Curious to hear thoughts of #ICU peeps. @ShashankSinhaMD @agtruesdell @Babar_Basir @thiele_holger

Paul Young

@DogICUma

3 years

The #TTM2trial was published today in the @NEJM Here’s a summary of what we did, what I think the trial means, and what next. @ttm2trial @nielsen_niklas @CritCareReviews @NEJM

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David J. Cohen, MD, MSc

@djc795

2 years

@Coronary4front @FaisalBakaeen @rodrigo_md_79 @RMSSAA @VictorDayan1 @GianTorre610 @pomyers @mmamas1973 @mirvatalasnag Sorry to be a curmudgeon, but the only thing this study suggests is that surgeons are good at selecting healthy octogenarians for CABG.

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David J. Cohen, MD, MSc

@djc795

5 years

@heartdoc45 Kayexalate deficiency

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David J. Cohen, MD, MSc

@djc795

4 years

Italy COVID-19 Update (Day 17) Data from Italy continue to look very encouraging-- especially with respect to cases. A couple of changes today: (1) Got rid of the spreadsheets; (2) Removed the first 5 days of data; (3) Adjusted y-axis scale on case graph.

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David J. Cohen, MD, MSc

@djc795

2 years

@mirvatalasnag @ovidiogarciav @SVRaoMD @VictorDayan1 @rwyeh @rahatheart1 @pomyers @rafasadaba @EduQuintanaCVS @FaisalBakaeen @pash22 @ajaykirtane @rojasfec @torresviera @Hragy @dompagano @essadii @tamaranihici @cardiojaydoc02 @Argenscore @OPreventzaMD @yourheartdoc1 @haithamahmedmd @dr_benoy_n_shah @DrAsifQasim @DavidLBrownMD One thing that continues to disappoint me is how some people continually critique RCTs for some minor concern but are willing to blatantly ignore obvious confounding in an observational study.

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David J. Cohen, MD, MSc

@djc795

10 months

@BaoGTran Thrombus. Air bubbles almost always split when they come to bifurcations. This one doesn't.

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David J. Cohen, MD, MSc

@djc795

6 months

@GreggWStone @webmd11 @kaulcsmc @pash22 @RichardWhitloc2 @Coronary4front @PCORI @FaisalBakaeen @JoeSabik @RuelMarc1 @RMSSAA @ovidiogarciav @VictorDayan1 @pomyers @gbiondizoccai @mmamas1973 @mirvatalasnag @GianTorre610 @JoChikweMD @rafasadaba @drjohnm @sbrugaletta @bugwonk @DavidLBrownMD The only people who think QOL isn't a big deal are people without the disease in question. Time after time, studies have shown that clinical trial leaders and academics do not prioritize the same things as our patients. Fortunately, patients are actually who we care about.

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David J. Cohen, MD, MSc

@djc795

4 years

Let's hope that in another couple of days this is so boring I can get back to my regular day job. 😀

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David J. Cohen, MD, MSc

@djc795

1 year

@rahatheart1 @rafasadaba @ovidiogarciav @Almanfi_Cardio @Coronary4front @FaisalBakaeen @mirvatalasnag @SukhNijjer 1/x- OK, for those of you have been waiting patiently for my thoughts as to why this study is so obviously confounded, here's the long tweetorial.

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David J. Cohen, MD, MSc

@djc795

9 months

@emily_fri IMHO, burnout is directly proportional to loss of control. No amount of lectures to anyone is going to fix this until physicians regain a reasonable amount of autonomy over how they practice medicine.

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