Matthew Budoff MD @BudoffMd Twitter profile

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@Gra_hughes

Matthew Budoff MD

@BudoffMd

1 year

Sad to report that a very physically active 66 year old patient with negative nuclear 2 years ago, taken off statin with 'clean bill of health', just passed away of SCD/MI with severe 3 VD. Wife had to do CPR. Wrong test, wrong answer. Need more CAC testing in asymptomatic pts

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Matthew Budoff MD

@BudoffMd

6 months

This trial doesn't invalidate the lipid hypothesis, is not the final answer (Progression of soft plaque at 1 year is the final study) and is exactly as originally designed - see i have no skin in the game. i am just presenting our findings

Diet-induced Elevations in LDL-C and Progression of Atherosclerosis - Tabular View - ClinicalTria...

Diet-induced Elevations in LDL-C and Progression of Atherosclerosis - Tabular View.

classic.clinicaltrials.gov

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Matthew Budoff MD

@BudoffMd

7 months

So Honored to have been awarded the physician if the year award by the California chapter of the ACC. So many great clinicians and researchers. Truly humbled. @ACCinTouch

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Matthew Budoff MD

@BudoffMd

3 years

Evaporate Trial presented at #escprev2021 as late breaker, showing Icosapent Ethyl can reduce Lipid Rich Necrotic Core and intraplaque hemorrhage, while increasing fibrous cap thickness on CT angiography. Understanding the mechanism is so important. @DLBHATTMD @SuvasiniL

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Matthew Budoff MD

@BudoffMd

1 year

My most important CAC paper to date just hit: CAC is SECONDARY RISK EQUIVALENT AT score >300 (same cohort, not comparing clinical trial patients to observational studies) @khurramn1 @RonBlankstein @ErinMichos @rblument1

Adults with high CAC score at similar risk for CV events as those with established ASCVD

Adults with a coronary artery calcium score greater than 300 are at an equivalent risk for major CV events as treated patients with established atherosclerotic CVD, supporting the use of high-dose...

www.healio.com

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Matthew Budoff MD

@BudoffMd

1 year

Nothing lowers risk more than a CAC of zero. see data from MESA. #Powerofzero I trust it in all asymptomatic except the young (< 40 years of age) to derisk my patients, including DM and FH @khurramn1 @rblument1 @RonBlankstein

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Matthew Budoff MD

@BudoffMd

6 months

If anyone would like to see the presentation (won an award at WCIR), here it is:

BREAKING – New Analysis of Heart Scan Data (CCTA) for Extremely high...

BREAKING: Dr Matt Budoff has now presented the matched analysis for: KETO (#LMHRstudy) vs Control (#MiHeart)METHODS – 80 Participants of #LMHRstudy fell with...

www.youtube.com

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Matthew Budoff MD

@BudoffMd

7 months

Very nice summary of some landmark articles in the world of coronary artery calcium in @rblument1

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Matthew Budoff MD

@BudoffMd

3 months

I still don't understand why colchicine continues to be disrespected - three positive outcome studies and CCTA plaque studies showing benefit, all for a 2a recommendation?

Colchicine and plaque: A focus on atherosclerosis imaging

Colchicine is an anti-inflammatory medication, classically used to treat a wide spectrum of autoimmune diseases. More recently, colchicine has proven …

www.sciencedirect.com

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Matthew Budoff MD

@BudoffMd

2 months

Add another 54% of 11,805 patients from Denmark with LDL > 193 mg/dl also with normal CAC. NOT Everyone needs a statin, i hold therapy for CAC Zero unless DM, known ASCVD in this population with no CAC.

Khurram Nasir

@khurramn1

3 months

61% Clinical FH patients with CAC Zero! Mean age 56 Loved the discussion #PowerOfZero getting more acceptance. #FactsAreFacts

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Matthew Budoff MD

@BudoffMd

3 years

Finally, CT angiography is the preferred test in US for a majority of patients with chest pain, following the UK (NICE) and ESC 2019 Guidelines. Great editorial by @RonBlankstein @DrMarthaGulati @lesleejshaw puts this in clinical perspective

Ron Blankstein

@RonBlankstein

3 years

Now out: The 2021 Multi Society Chest Pain Guideline A special thanks to the entire writing group led by @DrMarthaGulati and to the countless others who have worked on this over the past several years 👏 @ACCinTouch @AHAScience & all partner societies 👉

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Matthew Budoff MD

@BudoffMd

2 years

Great new study in NEJM Today - DISCHARGE Study, a large randomized trial confirms the CONSERVE Trial results that CTA is safer and results in similar outcomes as an invasive angiography first strategy. @NEJM @Heart_SCCT

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Matthew Budoff MD

@BudoffMd

2 years

Great new paper in @JACCJournals showing CAC has highest AUC and best reclassification (especially downward - Power of Zero). @khurramn1 @RonBlankstein @MichaelJBlaha @rblument1

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Matthew Budoff MD

@BudoffMd

3 years

Yesterday marked another COVID Vaccine milestone - More Than 3.01 Billion Shots Given Globally. If there are any major health concerns, we would have seen it. The largest "N" of any study ever.

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Matthew Budoff MD

@BudoffMd

1 year

A nice article demonstrating the harms of too much exercise. We have long seen the associated harms of marathon running on CAC and CV events, this article breaks it down between exercise volume and intensity. .

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Matthew Budoff MD

@BudoffMd

5 months

For those confused about LDL cholesterol, it is also about obesity, coronary artery calcium and other risk factors like Diabetes. No one risk factor stands alone to predict risk

Cardiovascular risk stratification among individuals with obesity: The Coronary Artery Calcium...

Among individuals with obesity, including moderate-severe obesity, CAC strongly predicts all-cause, CVD, and CHD mortality and may serve as an effective cardiovascular risk stratification tool to...

pubmed.ncbi.nlm.nih.gov

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Matthew Budoff MD

@BudoffMd

1 year

Likely the best algorithm on when to incorporate CCTA in primary prevention, and then what to do with the results. #yesCCT @Heart_SCCT -Free article at @AJPC

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Matthew Budoff MD

@BudoffMd

2 years

If anyone is still grasping at the 'toxicity' of mineral oil to explain away the benefits of EPA, please see @DLBHATTMD @SuvasiniL

Omega-3 Icosapent Ethyl and Stroke Reduction in Atherosclerotic Vascular Disease

Hear about the hottest ASCVD topics presented at the International Stroke Conference! Topics range from the latest data to risk factors to watch out for across the spectrum of disease. A stroke...

medtelligence.net

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Matthew Budoff MD

@BudoffMd

3 years

You can't make an asymptomatic person feel better with a stent, so treat medically and if patient has breakthrough angina, can always stent the LAD

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Matthew Budoff MD

@BudoffMd

3 years

Great article on Coronary artery calcium in @nytimes

Should I Take a Heart Drug? A Coronary Calcium Scan May Help You Decide. (Published 2021)

Many doctors recommend the heart test to pinpoint which patients would benefit from treatment to reduce their cardiovascular risk.

www.nytimes.com

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Matthew Budoff MD

@BudoffMd

2 years

We have great long term data from Walter Reed showing those persons with CAC=0 derive 0% benefit from 10+ years of statins. This is one of many such studies. Let's treat the disease, not everyone dies of CVD.

Impact of Statins on Cardiovascular Outcomes Following Coronary Artery Calcium Scoring - PubMed

In a largescale cohort without baseline ASCVD, the presence and severity of CAC identified patients most likely to benefit from statins for the primary prevention of cardiovascular diseases.

pubmed.ncbi.nlm.nih.gov

Dr. Deepak L. Bhatt

@DLBHATTMD

2 years

#cardiology #cardiotwitter #prevention #lipids

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Matthew Budoff MD

@BudoffMd

2 months

Our new paper on colchicine and plaque just published

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Matthew Budoff MD

@BudoffMd

9 months

A critically important study published today by Drs Maron and Rodrigues in @JACCJournals showing incidental CAC from ungated studies predict events and offer patients and clinicians a NO-COST opportunity to treat ASCVD. 2x risk of death with CAC > 100. RADIOLOGISTS - REPORT CAC

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Matthew Budoff MD

@BudoffMd

11 months

See the updated "Calcium Club" meeting at ASPC, a group that dates back to the late 1990s promoting prevention through imaging @rblument1 @MichaelJBlaha @khurramn1 @Agatston_Center @RonBlankstein

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Matthew Budoff MD

@BudoffMd

11 months

a great new review paper by my colleague @JairoaldanaMD discussing all the data we have on decreasing coronary plaque with different therapies. @DLBHATTMD

Regression and stabilization of atherogenic plaques

Atherosclerotic plaque assessment has become a crucial element in the examination of cardiovascular diseases. Plaque may exhibit progression and could…

www.sciencedirect.com

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Matthew Budoff MD

@BudoffMd

2 years

Hard to believe, but Steve Nissen is advocating for use of coronary calcium. Better decades too late, then never at all.

Primary and secondary prevention of atherosclerotic cardiovascular disease: A case-based approach

Estimating the risk of atherosclerotic cardiovascular disease (ASCVD) is a daily challenge for clinicians and is crucial to tailoring preventive medical care and guiding shared decision-making. New...

www.ccjm.org

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Matthew Budoff MD

@BudoffMd

2 years

Rita - Taylor and O'Malley did randomized studies with CAC specifically showing no increase in anxiety, depression or somatoform disorders using CAC, so your RCT is asked and answered. They also showed a 3.53 fold improvement in statin compliance over 4 years with CAC.

Rita Redberg

@RFRedberg

2 years

CAC scans offer no clinical benefits, often lead to more tests and worry, incidental findings and radiation risk. Need to rethink their use. Time for an RCT!

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Matthew Budoff MD

@BudoffMd

2 years

The United States is now catching up to established medical pathways in Europe and the UK for years. CCTA has the best clinical, outcome and cost-effectiveness data of any diagnostic test in Cardiology. We need to continue to move towards the best algorithms for our patients

Rep. Ted Lieu

@RepTedLieu

2 years

Heart disease is the leading cause of death in the United States. That's why we led 14 Members in urging @CMSGov to cover the use of the cutting-edge CCTA test to detect coronary artery disease. Our letter #ICYMI :

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Matthew Budoff MD

@BudoffMd

1 year

CT CAC data bests genetic factors for heart disease risk assessment Our JAMA paper today showed CAC score is more effective at predicting a person's risk for heart disease than polygenic risk scores. @AuntMinnie

Coronary Artery Calcium and Polygenic Risk Scores to Predict CHD

This study involving 2 large, community-based, longitudinal, cohort studies whether adding 2 markers—coronary artery calcium score and polygenic risk score—to traditional risk factor–based scores...

jamanetwork.com

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Matthew Budoff MD

@BudoffMd

4 years

The presentation Late-Breaking Science in Lipids showing Icosapent Ethyl reduces plaque progression in EVAPORATE will be available on the On-Demand platform within 24 hours #ESCCongress 2020

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Matthew Budoff MD

@BudoffMd

5 months

So excited to see our CONFIRM paper on CAC 300 and secondary prevention was the most talked about paper at JACC CI last year - and on the most read list -

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Matthew Budoff MD

@BudoffMd

4 months

My recent review on plaque imaging - enjoy

CT Coronary Calcium Scoring, Hard Plaque and Soft Plaque Visualization: Where Are We At?

A video from Matthew Budoff (as part of Scripps Health), posted on Jun 28, 2022.

www.vumedi.com

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Matthew Budoff MD

@BudoffMd

7 months

A reminder of power of CAC (and CCTA). Fuchs showed CAC Score of >300 associated risk of 7.05 for MI. Whether an 8-fold increased risk with obstructive-extensive disease by CCTA is superior to 7 fold increased risk with CAC needs exploration @khurramn1

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Matthew Budoff MD

@BudoffMd

1 year

How far our society has fallen. Yesterday was the proclaimed "Day of Hate" where anti-semitic activities were being coordinated on a national level by neo-nazis. I spent my Saturday morning driving around my Temple to provide extra eyes and ears to the security guard we employ.

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Matthew Budoff MD

@BudoffMd

4 years

Please join me at ESC this year to hear about results from icosapent ethyl in the EVAPORATE - FINAL. Free Registration for this virtual meeting. @the_lundquist @Heart_SCCT @ASPCardio

Dr. Deepak L. Bhatt

@DLBHATTMD

4 years

Just announced! EVAPORATE final results at ESC 2020 as a late-breaker presented by @BudoffMd - @SuvasiniL

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Matthew Budoff MD

@BudoffMd

2 months

Great abstract at ACC, garnered a lot of press about post-menopausal women and CAC progression:

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Matthew Budoff MD

@BudoffMd

6 months

Please join me at the cedars advances in nuclear cardiology, cardiac ct, and mri meeting this January

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Matthew Budoff MD

@BudoffMd

1 year

Another great study demonstrating that rapid CAC progression is associated with all-cause mortality. If CAC is progressing, more needs to be done. This is not just 'statin' effect of increased density, rapid progression infers worsening atherosclerosis

Coronary artery calcium progression and all-cause mortality - PubMed

Annualized CAC progression of greater than 20 units per year significantly predicts all-cause mortality. This may add clinical value in encouraging close surveillance and aggressive treatment of...

pubmed.ncbi.nlm.nih.gov

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Matthew Budoff MD

@BudoffMd

1 year

Great results of Vascepa's effect on physiology, another piece of the puzzle explaining cardiac benefit @DLBHATTMD

Vascepa’s Coronary Physiology Impact | Stress & CVD - Cardiac Wire

Amarin's Vascepa improves coronary physiology, exploring stress' CVD impact, and plenty of other cardiology news.

cardiacwire.com

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Matthew Budoff MD

@BudoffMd

2 years

@ehj_ed @ESC_Journals So important to see these external validations of REDUCE-IT in clinical trials. As a preventive cardiologist, this is one of several very important tools in my toolbox, advocated by EVERY major society that looked at the data. Every group, except some rogue naysayers on twitter

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Matthew Budoff MD

@BudoffMd

3 months

A great paper showing the Power of Zero even in symptomatic persons undergoing angiography

Coronary Artery Calcium Score Predicts Major Adverse Cardiovascular Events in Stable Chest Pain |...

Background Coronary artery calcium (CAC) has prognostic value for major adverse cardiovascular events (MACE) in asymptomatic individuals, whereas its role in symptomatic patients is less clear....

pubs.rsna.org

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Matthew Budoff MD

@BudoffMd

8 months

An excellent review of the power of zero and the low prevalence of non-calcified plaque when CAC = 0. by my former fellows - Irfan Zeb and Yasmin Hamirani

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Matthew Budoff MD

@BudoffMd

1 year

Even more important that the primary prevention cohort saw a 32% event reduction. So unique in so many ways. First study in statin intolerant, first with 48% women, first to show non-statin benefit in primary prevention.

Thomas Dayspring

@Drlipid

1 year

CLEAR Outcomes trial presented & published today- Bempedoic acid moves to the big league of proven LDL lowering (via LDLR clearance of apoB-LP drugs). Amazing results considering the drop in lipid Rx in placebo group. @society_eas @nationallipid

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Matthew Budoff MD

@BudoffMd

4 months

Great paper reminding us that CAC predicts stroke as well as other ASCVD events @khurramn1

Coronary artery calcium for stroke mortality prediction - PubMed

Coronary artery calcium for stroke mortality prediction

pubmed.ncbi.nlm.nih.gov

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Matthew Budoff MD

@BudoffMd

8 months

We are delighted to announce the online publication of our research paper (open access), which explores the combination of computed tomography angiography with coronary artery calcium scoring to improve the diagnosis of coronary artery disease.

Combination of computed tomography angiography with coronary artery calcium score for improved...

European Radiology - Coronary computed tomography angiography (CCTA) has higher diagnostic accuracy than coronary artery calcium (CAC) score for detecting obstructive coronary artery disease (CAD)...

link.springer.com

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Matthew Budoff MD

@BudoffMd

1 year

Our analysis of the RESPECT Trial (EPA and outcomes, AHA 2022) is now published

Fourth Study to Show Consistent Benefit of Highly Purified Eicosapentaenoic Acid on Cardiovascular...

www.mdedge.com

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Matthew Budoff MD

@BudoffMd

2 years

Congrats to Corcal study in @JACCJournals (CI) - The investigators concluded that CAC guidance may be a more efficient, personalized, cost-effective, and motivating approach to statin initiation and maintenance in primary prevention.

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Matthew Budoff MD

@BudoffMd

2 years

Thanks to all my co-authors that each contributed, and especially to @ASPCardio and President Peter Toth for helping shepherd this important paper through. @SuvasiniL @ErinMichos @khurramn1 @AChoiHeart @ChinnaiyanMD @MichaelJBlaha

Erin D. Michos, M.D.

@ErinMichos

2 years

#YesCCT ! Check out this @ASPCardio Practice Statement led by @BudoffMd , written with all-star team of authors, about the use Cardiac CT Angiography in Current Practice & Implications for CVD Prevention. The intersection of #cvImaging & #cvPrev . @AJPCardio

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Matthew Budoff MD

@BudoffMd

5 months

So proud to be associated with this study as the imaging core lab director. Will have great data emerging about this at risk population

NIH NHLBI

@nih_nhlbi

5 months

Check out our feature story on the RURAL Cohort Study, a long-term research project aimed at assessing the health of residents in the rural South. The study uses a high-tech research clinic on wheels that travels throughout the region. Read here:

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Matthew Budoff MD

@BudoffMd

2 years

And we have 7 (yes 7) prospective trials showing EPA slows or reverses atherosclerosis by QCA, IVUS, OCT, and CCTA, including CHERRY and EVAPORATE Trials. 10 trials is enough. EPA lowers events and slows atherosclerosis.

Christopher Cannon, M.D. 🇺🇦

@cpcannon

2 years

It’s the EPA…. A third trial showing benefit with EPA! (The original JELIS, then REDUCE-IT, and now RESPECT EPA).

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Matthew Budoff MD

@BudoffMd

2 years

Except for the fact that the warranty of a normal CCTA is probably 7-10 years (not 2 years) and the use of CCTA is preferred in men to age 70 (median cac 211) and women up to at least age 75 (median cac 67), this certainly represents a move in the right direction.

Journal of Cardiovascular CT

@journalCCT

2 years

Check out this review article of the new chest pain guidelines The 99 page document is distilled into 10 key messages for #YesCCT use @CardiacCTGuy @AChoiHeart @DrKelleyBranch @armin_zadeh @RonBlankstein @lesleejshaw @ToddVillinesMD

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Matthew Budoff MD

@BudoffMd

5 months

And our paper on Major Global Coronary Calcium Guidelines also made the most read list:

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Matthew Budoff MD

@BudoffMd

10 months

See how CAC outperforms ABI in this MESA study.

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Matthew Budoff MD

@BudoffMd

1 month

a new study last month in @JACCJournals about the validation of Cleerly's AI-guided coronary CT angiography technology, Enabling a one-stop comprehensive analysis of plaque, stenosis and ischemia detection in a single exam.

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Matthew Budoff MD

@BudoffMd

1 year

Important paper linking osteoporosis to atherosclerosis in MESA - We can learn so much from opportunistic screening with CT BMD at no additional scanning or radiation @bdi_ai

Association between coronary artery calcium and thoracic spine bone mineral density: Multiethnic...

Results from this cross-sectional analysis of a large population based ethnically diverse cohort indicate a significant inverse relationship between thoracic BMD and CAC in both genders independent...

pubmed.ncbi.nlm.nih.gov

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Matthew Budoff MD

@BudoffMd

1 year

Nice story of the LDL-CAC Paper by Mortensen.

Zero CAC? LDL Cholesterol May Not Predict MI, ASCVD

Patients with elevated LDL and coronary calcium faced increased risks of events, but having zero calcium appeared protective.

www.tctmd.com

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Matthew Budoff MD

@BudoffMd

1 year

@khurramn1 @RonBlankstein @ErinMichos @rblument1 Now available for free download from JACC CI Important for Prevention @DrMarthaGulati @bjcohenmd @MichaelJBlaha @Cleerlyhealth @CtLundquist

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Matthew Budoff MD

@BudoffMd

4 years

I pray that FDA follows suit and approves a vaccine. 1500 Americans die every day of Covid. the vaccine has the potential to reduce that, and every day the FDA delays, another 1500 americans die. We can do postmarketing surveillance and see how we all do with the vaccine

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Matthew Budoff MD

@BudoffMd

1 year

As we continue to learn, the presence of CAC with elevated LDL is the most robust predictor of whom is at risk of 'high' LDL. Not everyone develops ASCVD from high lipids, just like all women do not develop breast cancer.

Thomas Dayspring

@Drlipid

1 year

Paraphrasing @MichaelDavidson (1) Aggressive Rx of apoB early in life is the key (2) Not a fan of current "10 yr risk-based" analysis - (3) need to relate apoB (LDL) to time (4) Polygenetic risk score is emerging & lipids relate more to genes than diet.

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Matthew Budoff MD

@BudoffMd

6 months

@DrNadolsky Spencer - not sure why you are making false claims on X. We did not exclude anyone with plaque, this is just blatantly false. The ONLY study we ever planned was plaque progression, and the trial is ongoing - results pending early 2024. I presented baseline data only so far.

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Matthew Budoff MD

@BudoffMd

2 years

Important study, reminding us that we see the aortic calcifications on PE studies, abdominal CT and lung cancer screening studies and can institute good therapy. Chris's approach to look back at old scans is a model we should all follow when we see new patients for prevention.

Christopher Cannon, M.D. 🇺🇦

@cpcannon

2 years

For risk stratification, I look in patient's charts for old CT scans, and if I find atherosclerosis - I treat to ASCVD target of LDL < 70 mg/dl. This trial shows the risk of abdominal Atherosclerosis matches that of CAC score.

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Matthew Budoff MD

@BudoffMd

1 month

Great article covering potential of aspirin use in high Lp(a). Maybe something we can do for our patients while we wait for specific therapies

Aspirin’s Lp(a) Potential | Anger's Endothelial Impact - Cardiac Wire

Aspirin's Lp(a) preventative potential, how anger damages blood vessels, and plenty of other cardiology news.

cardiacwire.com

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Matthew Budoff MD

@BudoffMd

3 years

New NEJM poll on CCTA or MPI for chest pain evaluation: cast your vote today @NEJM

Imaging in Coronary Artery Disease Risk Stratification | NEJM

This interactive feature about estimating the risk of coronary disease offers a case vignette accompanied by two essays supporting different approaches to imaging for coronary disease risk ...

www.nejm.org

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Matthew Budoff MD

@BudoffMd

4 years

Became part of the solution yesterday. Enrolled in the Oxford Vaccine trial. I believe in vaccines, I believe in clinical trials, so I participated. @the_lundquist

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Matthew Budoff MD

@BudoffMd

9 months

As we enter the age of AI, we must remember, simple reporting of incidental CAC may change outcomes.

CAC Found on Noncardiac CT Scans Linked to Prognosis

The study used an AI algorithm to quantify CAC, but merely identifying its presence could be useful, Matthew Budoff says.

www.tctmd.com

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Matthew Budoff MD

@BudoffMd

2 years

An area we are actively studying with serial CCTA in a prospective trial. Ketogenic diets with pronounced LDL responses. See this manuscript just published:

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Matthew Budoff MD

@BudoffMd

4 months

So important to understand the benefits of EPA, as compared to EPA/DHA. Not sure why many of my colleagues don't get it, but this is another important paper demonstrating that benefit.

Dr. Deepak L. Bhatt

@DLBHATTMD

4 months

Do patients benefit from omega-3 fatty acids? #cardiology #cardiotwitter #prevention @gabrielsteg

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Matthew Budoff MD

@BudoffMd

3 years

Inspired by the actions of my fellow health care professionals who saved a life last night at the Hollywood Bowl. Stepped up, did bystander CPR and saved a young woman's life, despite any unknown COVID risks.

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Matthew Budoff MD

@BudoffMd

2 years

Great CAC Review at nice work @rblument1 @miguelcainzos23

The Ever-Growing Role of Coronary Artery Calcium in Primary Prevention - American College of...

www.acc.org

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Matthew Budoff MD

@BudoffMd

2 years

So important to remember the Power of Zero, a population based study showing extremely low risk in patients with CAC zero. What we have been saying all along. @rblument1 @RonBlankstein @ErinMichos

Khurram Nasir

@khurramn1

2 years

#1 Dreams do come true, needed a spark in 2014, health system @BaptistHealthSF inspired to make difference, bold leadership ( @JackZiffer @DrBTKatzen @Calvinchb @drjbone1 & others), generous community coming together #MiamiHeartStudy to realize the first fruit of these efforts👇

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Matthew Budoff MD

@BudoffMd

3 years

So important to recognize that CAC and CCT are critical evaluations for women as well as men. No difference in false positives as seen with nuclear. Glad to see @ACCinTouch promoting this use (finally).

Suvasini Lakshmanan

@SuvasiniL

3 years

Data continues to favor #YesCCT even in women. I am grateful for the mentorship on this piece @AAgarwalaMD @BudoffMd Thank you @ACCinTouch ! @Heart_SCCT @AChoiHeart @UIowaCVFellows @SDRoyMD @HritaniRama @Nidhi_Madan9 @lesleejshaw

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Matthew Budoff MD

@BudoffMd

4 years

Missed the EVAPORATE Presentation (as it was live at 3 AM EST) Saturday morning? find it here: View on demand @escardio Thanks for all the support.

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Matthew Budoff MD

@BudoffMd

10 months

Great article by @JairoaldanaMD on ccta regression studies.

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Matthew Budoff MD

@BudoffMd

2 years

Just Published @ASPCardio CAC Practice statement (open access): @ErinMichos @DrNathanWong @kcferdmd @DrMichaelShapir

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Matthew Budoff MD

@BudoffMd

1 year

An important new paper from our bone density research showing the relationships between bone density and CAC in MESA.

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Matthew Budoff MD

@BudoffMd

2 years

At AHA, i did an updated brief review on the mechanistic imaging studies related to Icosapent Ethyl

Mechanistic clues to understanding the benefits of icosapent ethyl

Mechanistic studies on plaque characteristics in patients receiving EPA can be insightful to understand the CV risk reductions seen in clinical trials. Prof. Budoff gives an overview of effects of...

pace-cme.org

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Matthew Budoff MD

@BudoffMd

2 years

An important paper, CAD RADS 2, so proud to be among the writing group lead by @cury_ricardo and @RonBlankstein , @Heart_SCCT , can download for free here:

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Matthew Budoff MD

@BudoffMd

2 years

Great talk on fish oils and outcomes, including the mineral oil issue, at ISC 2022 @AHAMeetings , @American_Stroke , with Mark Alberts, Lawrence Leiter. Builds on work from @SuvasiniL @DLBHATTMD and so comprehensive, worth a view.

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Matthew Budoff MD

@BudoffMd

2 years

Every paper since Steve Haffner's original paper have suggested diabetes is about 50% the risk of prior MI. CAC > 300 is similar to prior MI, new data coming out, so if you want CVD risk equivalent, get a CAC scan, with or without DM.

Khurram Nasir

@khurramn1

2 years

@drpablocorral Thankfully we are overcoming dogmatic belief for so many years DM CVD equivalent👍

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Matthew Budoff MD

@BudoffMd

2 years

So happy to be walking the halls of AHA and seeing so many giants of cardiology in one place. Inspiring. Bob Eckel, Carl Pepine, Roger Blumenthal, Bob Rosenson, Steve N, keith Ferdinand, the list goes on. Live meetings are critical to advance science

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Matthew Budoff MD

@BudoffMd

1 year

I believe the EVAPORATE Trial approach will become a standard approach, measuring plaque burden AND physiology with #FFRCT #YesCCT

Mark Rabbat MD

@MGRabbatMD

1 year

My thoughts on our publication demonstrating improvement in coronary physiology with icosapent ethyl using #FFRCT . Our study is the first to suggest #FFRCT can be a way to assess the effect of cardiovascular drugs. @DLBHATTMD @BudoffMd @CardiologyToday #YesCCT @Heart_SCCT

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Matthew Budoff MD

@BudoffMd

2 years

David - that is just not true. Eisner was not an outcome study, it showed CAC improved compliance, lowered blood pressure, cholesterol and weight. it was not powered, and did not show, any significant outcome difference as it was 2,137 patients randomized to cac/no-cac.

Less-Is-More Cardiologist

@DavidLBrownMD

2 years

@RFRedberg You mean another RCT. EISNER showed no benefit (in fact, an increase in death/MI) from calcium scanning.

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Matthew Budoff MD

@BudoffMd

8 months

Such an important paper showing increased CAC slope the steepest among SA, correlating with the high risk of DM and CVD in this population.

Jamal Rana, MD

@JamalRanaMD

8 months

Our much awaited paper from #MESA & #MASALA ❤️. Diabetes ⬆️ likelihood CAC in #SouthAsians (SA) & Whites. Clinically significant > 100 CAC in SA & Chinese. ⬆️ fasting glucose ⬆️CAC in SA. Led by Dr. Premyodhin. @DrNathanWong @BudoffMd @alka_kanaya

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Matthew Budoff MD

@BudoffMd

1 year

Statin intolerance in CLEAR OUTCOMES required this form to be signed by both patient and physician #CardsJC

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Matthew Budoff MD

@BudoffMd

4 years

Time to move beyond functional testing. Referrals leading to only 45% prevalence of obstructive disease in the cath lab is not acceptable anymore.

Lisa Laird

@LairdLi_PA

4 years

Data from 385,000 - functional testing suboptimal #CVD #HID2020 Matthew J Budoff MD

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Matthew Budoff MD

@BudoffMd

1 year

On a positive note, I am very excited about going back live to American College of Cardiology in New Orleans next week. Hope to see many friends and colleagues. #ACC23 / #WCCardio

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Matthew Budoff MD

@BudoffMd

9 months

This is the article on incidental CAC and outcomes:

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Matthew Budoff MD

@BudoffMd

2 years

So pleased that our Primer on CT imaging in Cardio-Onc is finally out - thanks to all co-authors @onco_cardiology @datsunian @CardiacCTGuy @CardioOnc_MR_CT and special thanks to editors at @JACCCardioOnc

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Matthew Budoff MD

@BudoffMd

4 years

Wanted to wish everyone a wonderful Thanksgiving. I am thankful for the incredible science that moved vaccines at (dare I say) warp speed. I am in the Oxford trial, Pfizer and Moderna look even better. Let's hope FDA can approve these and get us all back together soon - ACC2021

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Matthew Budoff MD

@BudoffMd

2 years

Congratulations, a well deserved recipient who has championed CAC testing and validated Power of Zero among many other important concepts with CAC, including leading the Calcium Consortium

Heart_SCCT

@Heart_SCCT

2 years

Congratulations to the 2022 Agatston Award recipient @MichaelJBlaha This award recognizes individuals whose pioneering efforts have saved lives from the leading killer throughout the world, coronary artery disease. @HopkinsMedicine @CiccaroneCenter @hopkinsheart

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Matthew Budoff MD

@BudoffMd

7 months

Very excited to again be part of the Advances in Nuclear Cardiology, Cardiac CT and Cardiac MRI: 37th Annual Case Review with the Experts this January at Cedars Sinai in Los Angeles.

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Matthew Budoff MD

@BudoffMd

2 years

So important to acknowledge AHA as recognizing that High value health care = CAC in intermediate risk patients (and low-intermediate risk patients). Need to keep moving the needle. @ASPCardio @American_Heart @DrMarthaGulati @ErinMichos @DrNathanWong

Khurram Nasir

@khurramn1

2 years

@pnatarajanmd @American_Heart @NEJM @CircOutcomes @vinaykiniMD @bnallamo @TYWangMD @KBreathettMD @wbborden Cac as high value test in intermediate risk patients!! Wow.. time has really changed something never imagined we will see these statements 5-10 yrs ago Kudos @MichaelJBlaha @BudoffMd @RonBlankstein @rblument1 @miguelcainzos23 and others getting to close this evidence gaps 👏👏

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Matthew Budoff MD

@BudoffMd

1 year

Nice Review of CCTA for acute chest pain, jby Suraj Dahal, a Class IA indication with 7 prospective trials showing superiority over nuclear, hs troponins, treadmill, standard of care and CCTA still comes out faster, less expensive and superior.

Coronary Computed Tomography Angiography for Evaluation of Chest Pain in the Emergency Department -...

Coronary computed tomography angiography has emerged as an important diagnostic modality for evaluation of acute chest pain in the emergency department for patients at low to intermediate risk for...

pubmed.ncbi.nlm.nih.gov

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Matthew Budoff MD

@BudoffMd

2 years

After the ACC/AHA Chest Pain guidelines badly botched the warranty issue with CCTA, we present the data on long term safety of a normal CCTA @journalCCT

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Matthew Budoff MD

@BudoffMd

1 year

Join me and some of the best young minds in cardiac CT on a discussion of the state of CAC testing on the DONUT OF DESTINY @SuvasiniL

A Journey in Calcium: Conversation with Dr. Matthew Budoff - Donut of...

Cohosts Suvasini, Kashif and Praveen are joined by the legendary Dr. Matt Budoff for a compelling conversation on the past, present, and future of coronary calcium and cardiac CT. Tune in and enjoy!

donutofdestiny.buzzsprout.com

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Matthew Budoff MD

@BudoffMd

3 years

Proud to be participating in a multi-modality diabetes treatment algorithm #DCRMDallasWorkshop , with many incredible collaborators @CBallantyneMD @ErinMichos @yhandelsmanmd @MkosiborodMD @DLBHATTMD @BiykemB among many, many others

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Matthew Budoff MD

@BudoffMd

4 years

A9. Yes, the St Francis Heart study showed that treating high CAC (>75th percentile) with atorvastatin 20 mg in a randomized trial lowers events by 30%, and those with CAC >400 by 42%. #NLATwitterChat #NLACAC

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Matthew Budoff MD

@BudoffMd

26 days

the first NIH funded study showing CT BMD can predict fractures:

NIH-Funded Study Shows BDI's Bone Density Test Using Existing CT Images Predicts Fractures

NIH study: BDI's CT bone test predicts fractures, aids early osteoporosis detection, cost-effectively. Visit www.bdi.ai.

www.businesswire.com

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Matthew Budoff MD

@BudoffMd

3 years

Big believer in CAC for diabetes, especially younger patients were guidelines are not so strong. Not all persons with diabetes have the same CV risk. CAC can help.

Khurram Nasir

@khurramn1

4 years

@VietHeartPA @APAC_Cardiology I hope the next guidelines can update Yes cac for diabetes... so much value in guiding intensity and choices on treatment All diabetics are not the same @BudoffMd @MichaelJBlaha @RonBlankstein @miguelcainzos23 @rblument1

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Matthew Budoff MD

@BudoffMd

3 years

There are still a few anti-statin and anti-CAC physicians out there, unfortunately, the editor of JAMA IM is one of them. Sad when we are there are those advocating AGAINST the guidelines and using positions of power to misinform clinicians. 30 years of science behind CAC.

Khurram Nasir

@khurramn1

3 years

@dmljmd @MichaelJBlaha @ErinMichos @DrMarthaGulati @braun_lynne @nstonedoc @rblument1 @JAMAInternalMed @ACCinTouch @AHAScience @ASPCardio @Heart_SCCT #1A reg CAC while we truly encourage discourse on its utility in clinical practice but truly saddening to see blatant misinformation propagated by @JAMAInternalMed @MInczeMD "risk calculators more accurate than CAC" Facts established by many NHLBI & international cohorts👇

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