NEJM @NEJM Twitter profile

Pinned Tweet

NEJM

1 month

A new CME program exploring the latest evidence on lifestyle, pharmacological, and surgical interventions, as well as recent progress in understanding the causes of obesity is now available. Learn more and sign up:

15

14

40

Last Seen Profiles

@Blazer_Gang

@inedasonok41864

@nvmss9

@Martin_notMarto

@FataAlnfood

@DahGbehanzin

@weloveprepping

@aeruichan

@Billy_ans

@MiaYunhee7890

@FundacionLaLiga

@CUCap

@widdwork34

@Burlesque_Beat

@Grancracker_

@oktay_gulizar

@DrSquatchSoapCo

@TUSPM

@maoxiaoying7777

@FinalBossFutbol

@PhilipsonThomas

@nas_oceana

@Dr2BS

@beneltham

@siswldrs

@Daily_SWGames

@RepeaterBooks

@maoxiaoying7777

@JMHS_Athletics

@stwmaniax

@39camera

@ProfRobinWilson

@riadkobaissi

@HusKingpin

@SLondonCitizens

@nihiinn_

NEJM

@NEJM

4 years

Why has the United States handled this pandemic so badly? The Editors note that although we came into this crisis with enormous advantages, our current political leaders have demonstrated that they are dangerously incompetent.

Dying in a Leadership Vacuum

nejm.org

967

18K

29K

NEJM

@NEJM

4 years

If medical students and trainees are taught to recognize symptoms of disease in only white patients and learn to perform lifesaving maneuvers on only male-bodied mannequins, medical educators may be unwittingly contributing to health disparities.

How Medical Education Is Missing the Bull’s-eye

nejm.org

62

3K

6K

NEJM

@NEJM

4 years

“Two semi-trailer trucks, cleverly marked as food-service vehicles, met us at the warehouse. When fully loaded, the trucks would take two distinct routes back to Massachusetts to minimize the chances that their contents would be detained or redirected.” #COVID19

Covid-19 Notes: In Pursuit of PPE

nejm.org

286

4K

5K

NEJM

@NEJM

4 years

Evidence is accumulating that eating in a 6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to ketone-based energy.

Effects of Intermittent Fasting on Health and Aging

nejm.org

83

3K

5K

NEJM

@NEJM

2 years

In double-blind RCT, ivermectin that was administered within 7 days after Covid-19 symptom onset was shown not to be of any clinical benefit.

3K

5K

NEJM

@NEJM

5 years

A 36-year-old man was admitted to the ICU with an acute exacerbation of chronic #heartfailure . After a ventricular assist device was placed & anticoagulation therapy initiated, hemoptysis developed, and he expectorated a cast of the right bronchial tree.

291

2K

4K

NEJM

@NEJM

6 years

Medical students have higher rates of depression, suicidal ideation, and burnout than the general population. Schools have begun revisiting their procedures to ensure that they are doing everything possible to meet the #mentalhealth care needs of their students.

Mental Health Services for Medical Students

nejm.org

115

4K

NEJM

@NEJM

6 years

The resident presented a patient admitted for chest pain after walking his dog. The attending asked, “What was the name of his dog?” The resident was stumped. Four years later, he’s not sure anything he’s carried from residency has been more useful than that question.

Perspective: The Name of the Dog

nejm.org

66

2K

4K

NEJM

@NEJM

4 months

A 70-year-old man undergoing cholangioscopy to evaluate dilatation of the common bile duct was found to have flatworms in his biliary tract (shown in a video). Read the full clinical case:

99

907

4K

NEJM

@NEJM

4 years

Two inoculations with a new SARS-CoV-2 mRNA-based vaccine that encodes a protein in the coronavirus spike elicited high titers of virus-neutralizing antibody in healthy adult volunteers. Virus-specific T-cell responses were also elicited. #COVID19 #SARSCoV2

Immunogenicity of a Candidate SARS-CoV-2 Vaccine

nejm.org

62

2K

3K

NEJM

@NEJM

6 months

A woman with hypertension presented to the clinic with a 4-day history of abnormal sounds in her ear. On examination, a small spider was seen moving within the external auditory canal of the left ear. The molted exoskeleton of the spider was also present.

271

781

3K

NEJM

@NEJM

5 years

A 66-year-old man presented with a 2-month history of abdominal bloating and worsening constipation. The physical examination revealed a painless pulsatile abdominal mass, which CT angiography revealed to be a large aortic aneurysm. Read the full case:

87

1K

3K

NEJM

@NEJM

4 years

Dying in a Leadership Vacuum #COVID19

Dying in a Leadership Vacuum

nejm.org

67

1K

3K

NEJM

@NEJM

3 years

Sex designations on birth certificates offer no clinical utility, and they can be harmful for intersex and transgender people. Moving such designations below the line of demarcation would not compromise the birth certificate’s public health function but could avoid harm.

Failed Assignments

nejm.org

5K

843

2K

NEJM

@NEJM

2 years

The just-announced U.S. Supreme Court decision in Dobbs v. Jackson Women’s Health Organization represents a stunning reversal of precedent that inserts government into the personal lives and health care of Americans.

433

1K

2K

NEJM

@NEJM

4 years

In this double-blind RCT in 1063 adults hospitalized with #COVID19 , a 10-day course of intravenous remidesivir was superior to placebo in shortening the time to recovery. The estimates of mortality at 14 days were 7.1% in the remdesivir group and 11.9% in the placebo group.

Remdesivir for Covid-19 — Preliminary Report

nejm.org

80

1K

2K

NEJM

@NEJM

6 years

Correspondence: An Unconscious Patient with a DNR Tattoo #MedicalEthics

100

4K

2K

NEJM

@NEJM

4 years

Just published: article from China CDC describes a novel coronavirus detected in patients with pneumonia whose specimens were tested at an early stage of the outbreak. The authors describe clinical features of the pneumonia in three of these patients.

A Novel Coronavirus from Patients with Pneumonia in China, 2019

nejm.org

33

2K

NEJM

@NEJM

6 years

The Nobel Prize in Physiology or Medicine has been awarded to James Allison & Tasuku Honjo “for their discovery of cancer therapy by inhibition of negative immune regulation.” Learn about Dr. Allison’s seminal work that has led to checkpoint-blockade immunotherapy.

Releasing the Brakes on Cancer Immunotherapy

nejm.org

11

1K

2K

NEJM

@NEJM

6 years

A 4-year-old boy makes a whistling sound while coughing. Bronchoscopy was performed, and an aspirated toy whistle was retrieved.

98

1K

2K

NEJM

@NEJM

1 year

Among school districts in the greater Boston area, the lifting of masking requirements was associated with an additional 44.9 Covid-19 cases per 1000 students and staff during the 15 weeks after a statewide masking policy was rescinded.

378

1K

2K

NEJM

@NEJM

1 year

Ventricular fibrillation and sudden death triggered by a blunt, nonpenetrating, and often innocent-appearing blow to the chest without damage to the ribs, sternum, or heart (and in the absence of underlying cardiovascular disease) constitute an event known as commotio cordis. 1/9

17

642

2K

NEJM

@NEJM

1 month

A 70-year-old man undergoing cholangioscopy to evaluate dilatation of the common bile duct was found to have flatworms in his biliary tract (shown in a video). Read the full clinical case:

57

448

2K

NEJM

@NEJM

4 years

A randomized controlled trial testing dexamethasone for Covid-19 (the RECOVERY trial) showed that, compared with usual care, this corticosteroid drug reduced 28-day mortality in hospitalized patients. #COVID19 #SARSCoV2

Dexamethasone Treatment in Covid-19

nejm.org

13

950

2K

NEJM

@NEJM

4 years

A cohort of patients with severe Covid-19 received treatment with remdesivir under a compassionate-use protocol. Improvement in oxygen-support status was observed in 68% of patients, and overall mortality was 13% over a median follow-up of 26 days. #COVID19

Compassionate-Use Remdesivir for Severe Covid-19

nejm.org

80

1K

2K

NEJM

@NEJM

4 years

Data on 8910 patients hospitalized with a diagnosis of #COVID19 were analyzed. Neither the use of angiotensin-converting–enzyme inhibitors nor the use of angiotensin-receptor blockers was associated with an increased risk of in-hospital death.

Covid-19, Cardiovascular Disease, and Drug Therapy

nejm.org

19

1K

2K

NEJM

@NEJM

4 years

Among 1376 patients with #COVID19 admitted to a NYC hospital, 59% were treated with hydroxychloroquine. After adjustment for baseline characteristics, there was no significant association between hydroxychloroquine treatment and the composite end point of intubation or death.

Observational Study of Hydroxychloroquine in Patients with Covid-19

nejm.org

74

1K

2K

NEJM

@NEJM

4 years

The authors hypothesize that angiotensin-converting enzyme 2 (ACE2) may be beneficial rather than harmful during lung injury and suggest that RAAS-inhibitor withdrawal may be harmful in some high-risk patients who have been exposed to Covid-19. #COVID19 #SARSCoV2

RAAS Inhibitors in Patients with Covid-19

nejm.org

15

1K

2K

NEJM

@NEJM

5 years

Just published: #Vaping use has rapidly increased. In this report from Wisconsin and Illinois Departments of Public Health, a severe respiratory illness in otherwise healthy young people is described.

Vaping-Induced Lung Injury

nejm.org

54

2K

NEJM

@NEJM

3 years

Nearly 600,000 people in a large Israeli health care organization were followed after vaccination for infection, hospitalization, and severe #COVID19 . Estimated vaccine effectiveness in preventing death was 72% after the first dose, and hospitalization was reduced by 92%.

Effectiveness of the BNT162b2 mRNA Vaccine in Israel

nejm.org

22

822

2K

NEJM

@NEJM

4 years

In this double-blind, randomized trial, 821 asymptomatic persons with a high- or moderate-risk exposure to #SARSCoV2 were assigned to receive hydroxychloroquine or placebo within 4 days after the exposure. No benefit in preventing illness compatible with #COVID19 was found.

Hydroxychloroquine for Covid-19 Postexposure Prophylaxis

nejm.org

57

1K

2K

NEJM

@NEJM

3 years

In a study involving 10.2 million participants in Chile, the effectiveness of an inactivated, China-developed #SARSCoV2 vaccine was estimated. Effectiveness was 65.9% for infection, 87.5% for hospitalization, 90.3% for ICU admission, and 86.3% for death.

Inactivated SARS-CoV-2 Vaccine in Chile

nejm.org

35

1K

2K

NEJM

@NEJM

1 year

An 18-year-old man presented with a 2-day history of fever, vomiting, and diarrhea. Three weeks before presentation, he had fallen into a canal. Physical exam was notable for the findings shown in the image. What is the most likely diagnosis?

145

208

2K

NEJM

@NEJM

5 years

Images in Clinical Medicine: Landolfi’s Sign

22

608

2K

NEJM

@NEJM

4 years

SARS-CoV-2 was detected in three cats after they were cohoused with cats that had been experimentally inoculated with the virus. Cats may be a silent intermediate host of SARS-CoV-2. #COVID19 #SARSCoV2

Coronavirus in Cats

nejm.org

101

1K

2K

NEJM

@NEJM

6 years

Medical students have higher rates of depression, suicidal ideation, and burnout than the general population and greater concerns about the stigma of mental illness. #meded

38

1K

2K

NEJM

@NEJM

4 years

Among hospitalized patients with #COVID19 , treatment with dexamethasone resulted in lower 28-day mortality than usual care, according to the level of respiratory support the patients were receiving, indicating a possible correlation between efficacy and the stage of infection.

Dexamethasone Treatment in Covid-19

nejm.org

9

777

1K

NEJM

@NEJM

4 years

Video in Clinical Medicine: How to Obtain a Nasopharyngeal Swab Specimen. #COVID19

How to Obtain a Nasopharyngeal Swab Specimen

nejm.org

22

871

1K

NEJM

@NEJM

5 years

A 73-year-old man presented with shortness of breath. On ocular exam, pupil dilation and constriction that were synchronized with his heartbeat were noted, a finding known as Landolfi’s sign. He was found to have severe aortic regurgitation.

19

595

1K

NEJM

@NEJM

3 months

Dengue outbreaks can affect 390 million persons yearly. In a trial involving 16,235 persons in Brazil, the live, attenuated, tetravalent Butantan vaccine was efficacious in all age groups at 2 years. Read the full trial results:

16

525

1K

NEJM

@NEJM

4 years

Among 215 pregnant women who were admitted to a New York hospital for delivery and who underwent universal testing for SARS-CoV-2, more than one of eight asymptomatic women had positive results, and most of the women with Covid-19 were asymptomatic. #COVID19 #SARSCoV2

SARS-CoV-2 Testing in Obstetrical Patients

nejm.org

27

1K

NEJM

@NEJM

2 years

In this trial of IV vitamin C in adult patients with sepsis, those who received a vitamin C infusion had a higher risk of death or persistent organ dysfunction at 28 days than those who received placebo. #CCR22

27

527

1K

NEJM

@NEJM

3 years

In the phase 3 mRNA-1273 trial participants received 2 doses of vaccine or placebo 28 days apart. The mRNA-1273 vaccine showed 94.1% efficacy in preventing #SARSCoV2 , including severe disease. #IDTwitter

Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine

nejm.org

25

571

1K

NEJM

@NEJM

3 years

A 7-year-old girl presented with 2 weeks of fever and painful blisters throughout the body. She completed a course of penicillin for tonsillitis two weeks earlier. Physical examination showed multiple bullae on her extremities and lesions on her lips. What is the diagnosis?

New NEJM Image Challenge

nejm.org

143

290

1K

NEJM

@NEJM

4 years

Review Article: Effects of Intermittent Fasting on Health, Aging, and Disease

Effects of Intermittent Fasting on Health and Aging

nejm.org

18

609

1K

NEJM

@NEJM

1 year

Alcohol use disorder is a major cause of advanced liver disease worldwide. Bataller and colleagues review the epidemiology, pathophysiology, and treatment of alcohol-associated hepatitis including the evidence for steroids and liver transplantation.

15

470

1K

NEJM

@NEJM

5 years

Anemia of inflammation is a common normocytic, normochromic anemia associated with systemic inflammation that increases the level of hepcidin and results in defective iron reuse from body stores. Reducing inflammation can help correct the defect.

Anemia of Inflammation

nejm.org

6

685

1K

NEJM

@NEJM

4 years

Increasing the proportion of SARS-CoV-2 infections that are asymptomatic with the simple public health measure of universal masking might help make the infection less deadly and increase population-level immunity without severe illnesses and deaths. #COVID19 #SARSCoV2

Facial Masking for Covid-19

nejm.org

34

783

1K

NEJM

@NEJM

5 years

The human connectome allows researchers to investigate functional connections between different regions of the brain and identify functional brain networks. Exploring these connections and networks can provide new insight into neurologic and neuropsychiatric symptoms.

Anatomical and Functional Connectivity Maps

nejm.org

19

677

1K

NEJM

@NEJM

5 years

Among patients hospitalized for pneumococcal pneumonia, the incidence of myocardial infarction is 7 to 8%. The true incidence of postinfection myocardial infarction may be higher than estimated, given the practice of attributing elevated troponin levels to “troponin leak.”

Acute Infection and Myocardial Infarction

nejm.org

7

798

1K

NEJM

@NEJM

6 months

In patients w/ cardiovascular disease & overweight or obesity but no diabetes, semaglutide was superior to placebo in lowering the risk of major adverse cardiovascular events at a mean follow-up of 39.8 mos. Full SELECT trial results: #AHA23 @AHAScience

Semaglutide in Obesity without Diabetes

nejm.org

12

516

1K

NEJM

@NEJM

3 years

Review Article: Pathogenesis of Migraine

Pathogenesis of Migraine

nejm.org

7

332

1K

NEJM

@NEJM

3 years

A 54-year-old woman presented with palpitations that were relieved when she passed gas or had a bowel movement. Computed tomography revealed the presence of the transverse colon within the pericardial cavity.

Intrapericardial Colon

nejm.org

74

333

1K

NEJM

@NEJM

4 years

In this report, investigators assess how long SARS-CoV-2 (HCoV-19) survives in the environment as compared to SARS-CoV-1. #COVID19 #SARSCoV2

Aerosol and Surface Stability of SARS-CoV-2

nejm.org

18

1K

NEJM

@NEJM

4 years

A 38-year-old man presented with low back pain associated with a herniated disk. A computed tomographic scan incidentally showed the presence of three kidneys.

Three Kidneys

nejm.org

29

402

1K

NEJM

@NEJM

4 years

Eighteen brains of patients who died 0 to 32 days after the onset of symptoms of SARS-CoV-2 infection showed hypoxic–ischemic changes but no encephalitis, meningitis, strokes, or changes in olfactory bulbs or tracts. #COVID19 #SARSCoV2

Brain Autopsy Series in Patients with Covid-19

nejm.org

14

653

1K

NEJM

@NEJM

4 years

Perspective: The members of the team that discovered insulin sold the patent to the University of Toronto for $1 each because they felt that the drug belonged to the public. Today, insulin is inaccessible to thousands of Americans because of its high cost.

The U.S. Insulin Crisis

nejm.org

31

958

1K

NEJM

@NEJM

4 years

Covid-19 Notes: Stroke in Young Patients with Covid-19

nejm.org

10

678

1K

NEJM

@NEJM

2 years

This case report describes a patient in Sweden who had an out-of-hospital cardiac arrest and received defibrillation with an automated external defibrillator delivered by a drone (shown in a video).

26

421

1K

NEJM

@NEJM

5 years

Our new Illustrated Glossary includes a wide range of simple, illustrated definitions of complex key terms. Explore this new feature:

15

519

1K

NEJM

@NEJM

4 years

Authors provide an epidemiologic analysis of first 425 confirmed cases of infection with #2019nCoV in Wuhan, China. This analysis provides estimates of the epidemic doubling time and the basic reproductive number and shows clear evidence of sustained human-to-human transmission.

Early Transmission Dynamics of 2019-nCoV

nejm.org

18

918

1K

NEJM

@NEJM

1 year

Research Summary: Acute Effects of Coffee Consumption on Health among Ambulatory Adults (CRAVE)

23

398

1K

NEJM

@NEJM

2 years

A 31-year-old man was admitted with perianal and penile ulcers, rectal pain, and vesiculopustular rash. He had first noticed itchy white “bumps” around the anus 9 days earlier.

60

321

1K

NEJM

@NEJM

1 year

Critical illness is a transformative and often traumatic event for the entire family. The authors summarize data on the outcomes and highlight the need to frame ICU care as part of a continuum of care for critically ill patients. #CriticalCare

22

546

1K

NEJM

@NEJM

3 years

Six patients previously infected with the original #SARSCoV2 virus received the BNT162b2 vaccine. Before vaccination, they had neutralizing activity against the B.1.1.7 and P.1 variants but not B.1.351. After one dose, neutralizing activity against all variants increased greatly.

Vaccination after SARS-CoV-2 Infection

nejm.org

16

441

1K

NEJM

@NEJM

1 year

Just released at #SCCM2023 : Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension #SCCMSoMe @sccm

18

435

1K

NEJM

@NEJM

4 years

In a consecutive series of 64 patients with Covid-19 and ARDS, severe agitation and corticospinal signs were common. In 2 of 13 patients, magnetic resonance imaging of the brain showed small acute strokes, and in 1 patient, this imaging showed a subacute stroke. #COVID19

Neurologic Features in SARS-CoV-2 Infection

nejm.org

24

697

1K

NEJM

@NEJM

6 years

#VisualAbstract : Using low-dose #aspirin as a primary prevention strategy in older adults results in a significantly higher risk of major hemorrhage and does not result in a significantly lower risk of CVD than placebo.

Cardiovascular Events and Bleeding with Daily Aspirin

nejm.org

16

921

1K

NEJM

@NEJM

4 years

In this experiment, investigators used a laser in a darkened box to visualize approximately 300 droplets that were generated during speech. #COVID19 #SARSCoV2

39

699

1K

NEJM

@NEJM

3 years

Image Challenge: A 5-year-old girl presented with 3 days of fevers, sore throat, and pain with swallowing. On examination, she had a temperature of 40°C, fissured lips, and a red tongue with enlarged papillae. What is the diagnosis?

New NEJM Image Challenge

nejm.org

303

216

1K

NEJM

@NEJM

1 month

Having benefited from excellent mentors over the course of her career, a physician concludes that a true mentor is someone who has more imagination about you than you have about yourself. Read the full Perspective:

17

355

1K

NEJM

@NEJM

5 years

Have a little extra time on Sunday? Catch up with the most-viewed review article of the week, "Lipid Management for the Prevention of Atherosclerotic Cardiovascular Disease."

Lipid Management for the Prevention of Cardiovascular Disease

nejm.org

9

480

1K

NEJM

@NEJM

5 years

Review Article: Stem Cells in the Treatment of Disease

3

629

1K

NEJM

@NEJM

5 years

Tumor progression is associated with subversion of immunity, and signals in the tumor microenvironment originating from cancer cells, stroma, and other immunocompetent cells set tumor-associated macrophages to a tumor-promoting mode. Learn more:

Macrophage Checkpoint Blockade in Cancer

nejm.org

7

650

1K

NEJM

@NEJM

5 years

During preparation for the transplantation of a kidney into a 9-year-old girl, the donor kidney was found to have five renal arteries.

21

373

1K

NEJM

@NEJM

6 years

Roughly half of medical students experience burnout, and 10% report suicidal ideation during medical school.

Mental Health Services for Medical Students

nejm.org

48

977

1K

NEJM

@NEJM

2 years

Following widespread falsehoods about Covid-19 and its treatment and prevention, the ABIM has informed doctors that disseminating misinformation is grounds for disciplinary sanctions.

339

324

934

NEJM

@NEJM

4 years

Two injections of an mRNA-based #SARSCoV2 vaccine elicited high levels of NAb and Th1 CD4 T-cell responses in rhesus macaques. Two days after challenge with intranasal and intratracheal virus, viral replication was undetectable in BAL fluid and nasal secretions. #COVID19

Messenger RNA–Based Covid-19 Vaccine in Nonhuman Primates

nejm.org

27

434

1K

NEJM

@NEJM

4 years

All NEJM #2019nCoV articles are free full text, including this Brief Report published yesterday. Visit for more.

A Novel Coronavirus from Patients with Pneumonia in China, 2019

nejm.org

6

730

1K

NEJM

@NEJM

4 years

Five patients with Guillain-Barré syndrome are described 5 to 10 days after onset of Covid-19 infection. Three had severe weakness with an axonal pattern on electrophysiologic studies, and two had normal cerebrospinal fluid protein. The virus was not found by in the CSF. #COVID19

Guillain-Barré Syndrome with Covid-19

nejm.org

12

657

1K

NEJM

@NEJM

4 years

The efficacy of tocilizumab was tested in an RCT involving patients with #COVID19 who had fever, pulmonary infiltrates, or a need for supplemental oxygen. The treatment had no significant effect on disease progression, independence from supplemental oxygen, or death.

Tocilizumab in Covid-19

nejm.org

17

618

1K

NEJM

@NEJM

3 years

A 62-year-old man with chronic obstructive pulmonary disease came to the ED with 2 days of dyspnea. He was admitted to the ICU while in hypercapnic respiratory failure and placed on intubation and ventilation. Five days later, his urine became green. Which medication caused this?

New NEJM Image Challenge

nejm.org

159

212

1K

NEJM

@NEJM

5 years

Don't miss our dedicated topic page to e-cigarettes and #vaping -related disease. See the NEJM articles that made news headlines.

E-Cigarettes and Vaping-Related Disease

nejm.org

14

720

995

NEJM

@NEJM

3 years

The trigeminal nerve and its projections to the intracranial vasculature — the trigeminovascular system — are at the nexus of migraine. Identification of the mechanisms that trigger signals in this system have led to targeted treatments and preventive therapies for migraine.

Pathogenesis of Migraine

nejm.org

7

322

990

NEJM

@NEJM

3 years

A 36-year-old woman presented with a 2-month history of cough and worsening shortness of breath. Chest x-ray is as shown. What is the diagnosis?

New NEJM Image Challenge

nejm.org

142

206

982

NEJM

@NEJM

4 years

In a randomized, placebo-controlled trial of 4745 patients with recent myocardial infarction, low-dose colchicine (0.5 mg once daily) prevented ischemic cardiovascular events. See the COLCOT trial. #AHA19

Low-Dose Colchicine After Myocardial Infarction

nejm.org

24

557

990

NEJM

@NEJM

5 years

Improvements in #cancer screening, early detection, and treatment are resulting in increased numbers of patients cured of cancer. These persons face a wide range of medical and psychosocial challenges that need to be planned for and appropriately managed. #oncology

Cancer Survivorship

nejm.org

19

651

973

NEJM

@NEJM

4 years

In this study, 20% of patients with Covid-19 had a prolonged activated partial-thromboplastin time (aPTT). In 90% of these cases, the cause was lupus anticoagulant, with no associated bleeding. Patients with Covid-19 are susceptible to thromboses. #COVID19

Prolonged aPTT in Patients with Covid-19

nejm.org

13

591

974

NEJM

@NEJM

5 years

The causative agents in aspiration pneumonia have shifted from anaerobic to aerobic bacteria. Challenges remain in distinguishing aspiration pneumonia from chemical pneumonitis. Read the full review article to learn about treatment and prevention strategies.

Review Article: Aspiration Pneumonia

nejm.org

8

581

965

NEJM

@NEJM

3 months

Portal hypertension: An increase in pressure gradient in any segment of the portal venous system. It is classified on the basis of the site of increased vascular resistance: extrahepatic or intrahepatic.

6

307

986

NEJM

@NEJM

4 years

In this autopsy series, the authors found that #SARSCoV2 has a tropism beyond the respiratory tract, including the kidneys, heart, liver, and brain. They speculate that tropism influences the course of #COVID19 disease and possibly aggravates preexisting conditions.

Multiorgan and Renal Tropism of SARS-CoV-2

nejm.org

17

621

960

NEJM

@NEJM

3 years

The B.1.617.2 or delta #COVID19 variant has spread worldwide. In a test-negative case–control study, the effectiveness of two doses of BNT162b2 was 94% against the B.1.1.7 variant and 88% against delta; with ChAdOx1 nCoV-19, effectiveness was 74% and 67%, respectively.

Vaccine Effectiveness against Delta Covid-19 Variant

nejm.org

15

528

952

NEJM

@NEJM

21 days

Science behind the Study: CAR T-Cell Therapy for Glioblastoma #Neurology

6

292

961

NEJM

@NEJM

3 years

Safety and Efficacy of the BNT162b2 COVID-19 Vaccine #COVID19 #IDTwitter

Safety and Efficacy of the BNT162b2 COVID-19 Vaccine

nejm.org

13

469

945

NEJM

@NEJM

7 months

This week’s most viewed articles: 1. Asthma in Adults #pulmonology #CriticalCare

2

331

945

NEJM

@NEJM

4 years

All @NEJM #COVID19 #SARSCoV2 articles are free full text.

Free access: Coronavirus (Covid-19)

nejm.org

20

646

918

NEJM

@NEJM

4 years

Patients with confirmed or suspected #COVID19 were randomly assigned to receive HCQ with AZM, HCQ alone, or usual care. The primary outcome was clinical status at 15 days. There were no significant differences between groups in the primary outcome.

Hydroxychloroquine with or without Azithromycin in Covid-19

nejm.org

29

554

928