Ethan J. Weiss Profile Banner
Ethan J. Weiss Profile
Ethan J. Weiss

@ethanjweiss

30,077
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Scientist (metabolism) & Cardiologist (prevention); 2 girls, 1 wife ( @PalmerWeiss ), 2 dogs; mostly @warriors these days

San Francisco
Joined December 2009
Don't wanna be here? Send us removal request.
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@ethanjweiss
Ethan J. Weiss
7 years
"This is what happens when people become attached to a theory. They fit the evidence to the theory rather than the theory to the evidence...
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@ethanjweiss
Ethan J. Weiss
4 years
I guess @united is relaxing their social distancing policy these days? Every seat full on this 737
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@ethanjweiss
Ethan J. Weiss
4 years
Remember when hardly anyone knew someone who had had COVID?
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@ethanjweiss
Ethan J. Weiss
3 years
Every once in a while you discover something that makes you stop and reflect that practically everything we argue about is meaningless
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@ethanjweiss
Ethan J. Weiss
4 years
We are about to land & I just wanted to say a few things. 1) people on this plane are scared/ shocked. 2) I have no idea why most of them are traveling. 3)I am with a group of 25 nurses and doctors who have been working in NYC hospitals for the past 2-4 weeks. We are coming home
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@ethanjweiss
Ethan J. Weiss
4 years
This is the last time I’ll be flying again for a very long time
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@ethanjweiss
Ethan J. Weiss
4 years
Also I guess a lot has changed in 10 days
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@ethanjweiss
Ethan J. Weiss
4 years
5) they could have avoided this by just communicating better. They literally just sent an email 10 days ago telling all of us the middle seats would be empty
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@ethanjweiss
Ethan J. Weiss
5 years
Call me fucking insane, but I don’t think the second amendment is working out very well
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@ethanjweiss
Ethan J. Weiss
4 years
Wow @UCSF is sending a team of clinicians to NY tomorrow for a month!
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@ethanjweiss
Ethan J. Weiss
4 years
1/ Today is Yom Kippur. Many Jewish people are fasting. I am not But I still want to talk about fasting…
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@ethanjweiss
Ethan J. Weiss
4 years
I don't think there is a way I can watch this too many times
@carlquintanilla
Carl Quintanilla
4 years
FAUCI to Sen. Paul: "You are not listening ... If you believe that 22% is 'herd immunity', I believe you're alone in that."
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@ethanjweiss
Ethan J. Weiss
4 years
4) United flew us here for free. They got a lot of great PR for taking great care of us on the way out including from me. Even from me:
@ethanjweiss
Ethan J. Weiss
4 years
And a whole group of people were there to greet us. It was not necessary but also very nice. Thank you @united . It meant a lot
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@ethanjweiss
Ethan J. Weiss
1 year
I don’t understand why people are so bothered by the fact that metabolic disease can be treated by medicines. It’s not that lifestyle solutions can’t work; they can! It’s that they don’t work for a very large number of people…
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@ethanjweiss
Ethan J. Weiss
8 years
Say what you want about her delivery, but for a year, 16 men tried & failed to hobble Trump. Tonight Hillary completely eviscerated him
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@ethanjweiss
Ethan J. Weiss
4 years
Also, this was the departure board at Newark when we were there around 12 noon. Not a lot of flights
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@ethanjweiss
Ethan J. Weiss
4 years
Day 3 (sorry) Day 4: Not the fucking flu
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@ethanjweiss
Ethan J. Weiss
2 years
What’s the closest you’ve ever been to being in a cult?
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@ethanjweiss
Ethan J. Weiss
4 years
How’s everyone’s alcoholism going?
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@ethanjweiss
Ethan J. Weiss
6 years
Those who know me also know that I love to brag on my kickass 11 year-old daughter, Ruthie, who is legally blind. She inspires me with shit like this every day
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@ethanjweiss
Ethan J. Weiss
4 years
Because we all need to laugh... ...and holy shit did this make me laugh as hard as I have in long time. No idea where it came from or who did it but this deserves an Academy Award for best short
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@ethanjweiss
Ethan J. Weiss
3 years
Out for a run this morning on a gloriously empty beach and sending buckets of love to the “I’m leaving San Francisco because it sucks”crowd
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@ethanjweiss
Ethan J. Weiss
4 years
I've said it before: It is astonishing we could pass universal seatbelt laws - an intervention that helps only the wearer - but we cannot enforce mask wearing - an intervention that helps everyone
@mkraju
Manu Raju
4 years
Asked if Trump should encourage Americans to wear masks through his Twitter account, Graham said: "Listen, I don't think he's going to change where he's at on masks.“
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@ethanjweiss
Ethan J. Weiss
3 years
It is shocking that democracy survived the totalitarianism brought on by seat belt laws now 30 years ago
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@ethanjweiss
Ethan J. Weiss
4 years
29/ We were surprised by these results. At that time, I had been doing 16:8 TRE for ~7 years. I stopped. This study taught me a lot. More later but the take home lessons for me are: 1) it is possible to do RCTs in nutrition; 2) ignore all nutrition studies without a control group
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@ethanjweiss
Ethan J. Weiss
4 years
I was asked to write a perspective on the potential use of CRISPR for genetic diseases/disorders. What came was very personal. It is not proscriptive. It is a perspective that I have now that I could not have had before
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@ethanjweiss
Ethan J. Weiss
6 years
I wanted to make a joke here but really there’s nothing remotely funny about this garbage
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@ethanjweiss
Ethan J. Weiss
8 years
If a President Trump scares you, chew on a President Trump with a Republican House and Senate
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@ethanjweiss
Ethan J. Weiss
5 years
I saw one of my favorite patients today who was explaining to me why he loves his primary care doctor (English not his 1st language): "You feel already better when you leave his office but you do not take a pill" I aspire to be this kind of doctor
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@ethanjweiss
Ethan J. Weiss
4 years
I kinda miss the days when @ScottGottliebMD used to scare the shit out of us for leaving the egg salad out for too long
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@ethanjweiss
Ethan J. Weiss
5 years
My life is not complete until I write a sentence like this in the @NEJM - "the urine was found to be in color a light straw, transparent, like highly clarified wine, wholly without odor, of a very pleasant sweet taste, resembling exactly a solution of loaf sugar in pure water
@NEJM
NEJM
5 years
From the #NEJMArchive : Notes of a Case of Diabetes Mellitus (Feb. 3, 1829)
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@ethanjweiss
Ethan J. Weiss
4 years
This map is obscene
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@ethanjweiss
Ethan J. Weiss
4 years
Amazing fact of the day: of the 58 patients admitted (to date) to UCSF with documented COVID, 16 remain in the hospital, 41 recovered and were discharged and just 1 (one) has died
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@ethanjweiss
Ethan J. Weiss
4 years
Joseph Costa, ICU doctor at Mercy Medical Center, dies of the coronavirus he worked to help others overcome
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@ethanjweiss
Ethan J. Weiss
4 years
An update Day 0:
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@ethanjweiss
Ethan J. Weiss
4 years
Too tired for a post tonight. Typically I hate national anything day but really it is such the right time to celebrate nurses. Being here in NY and seeing it up close - nobody would believe what these people do. Thank you nurses!! Thank you so much!!! #NationalNursesDay
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@ethanjweiss
Ethan J. Weiss
4 years
Someone named Ethan Weiss reached out to me by DM on Instagram and said "Love the name". He then added me to a group of 20 Ethan Weisses. It's insane
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@ethanjweiss
Ethan J. Weiss
4 years
Yeah it sucks here
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@Jim_Jordan
Rep. Jim Jordan
4 years
Americans love America. They don’t want their neighborhoods turning into San Francisco.
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@ethanjweiss
Ethan J. Weiss
4 years
What a freaking disaster
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@ethanjweiss
Ethan J. Weiss
2 years
Self-care
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@ethanjweiss
Ethan J. Weiss
4 years
Very interesting data here: A Detailed Map of Who Is Wearing Masks in the U.S. “The big takeaway of all of the data is partisanship is the big determinant of all of the behavior,” she said. “It’s not age. It’s not where you live.”
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@ethanjweiss
Ethan J. Weiss
4 years
28/ So in summary: 1) no matter how you slice it, prescription of TRE is not a very effective weight loss strategy; 2) There was no advantage to TRE when compared to a proper control group; 3) What weight was lost looked to come more from muscle mass than fat mass
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@ethanjweiss
Ethan J. Weiss
4 years
I was asked by the wonderful people at @statnews to adapt my much longer piece on gene editing (). With great help, we landed here... Should ‘broken’ genes be fixed? My daughter changed the way I think about that question
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@ethanjweiss
Ethan J. Weiss
4 years
The networks have a strong incentive to keep this story alive as long as possible. I don't blame them. I just choose to ignore them. The race is over. It has been for days. I have moved on. Congrats President-Elect Biden
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@ethanjweiss
Ethan J. Weiss
5 years
As some of you may know and some of you may wish not to know, I started a little experiment about 10 months ago and began eating a low-carb and high fat diet for the first time in my life. I have not been tracking macros specifically but I can say a few things:
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@ethanjweiss
Ethan J. Weiss
3 years
I am at the "my next tweet is going to get me fired" phase of 2021
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@ethanjweiss
Ethan J. Weiss
4 years
31/ Lastly, there is so much left to learn here. We are going to stay at it and try to answer some of the obvious next questions. Really this is just the beginning. But again, massive thank you to Dylan who is a star clinical researcher in the making
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@ethanjweiss
Ethan J. Weiss
4 years
Day 2: Baby Steps
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@ethanjweiss
Ethan J. Weiss
4 years
It’s 8:20AM
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@ethanjweiss
Ethan J. Weiss
7 years
1. I have a story to tell about our healthcare system and how it's not working very well
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@ethanjweiss
Ethan J. Weiss
2 years
80 mg Lipitor for < $5/month. That’s less than most copays. Wow
@mcuban
Mark Cuban
2 years
If you need to buy generic drugs, sign up and try our pricing. EVERYTHING we sell is cost plus 15%.
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@ethanjweiss
Ethan J. Weiss
3 years
I have come to know and respect @ProfEmilyOster well. I think of her as a friend. So I have bias. I thought her piece was provocative and interesting. I don’t think it was prescriptive. Whatever one thinks, the reaction to it has been gross. It’s been fucking embarrassing
@ProfEmilyOster
Emily Oster
3 years
Obviously that Atlantic article was upsetting to many people, many of whom I respect and admire. I wanted to respond. My goal in the article was to help parents understand what many people say when they say children are "low risk" (1/n)
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@ethanjweiss
Ethan J. Weiss
3 years
When you wonder why people are so angry
@bennyjohnson
Benny Johnson
3 years
This is the most heartbreaking thing I have watched in 2020. These people are monsters Wow.
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@ethanjweiss
Ethan J. Weiss
4 years
A gentle reminder: when you’re out on a walk or a run & dutifully keeping your safe distance from others, it’s still acceptable to look that person you pass in the eye & SMILE - even if you are both wearing masks. We need it now more than ever
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@ethanjweiss
Ethan J. Weiss
6 years
Kids, let this be a lesson: When you have sex with a Playboy model days after your 3rd wife gives birth to your 5th child & then you want to arrange to pay $ to keep such model quiet, be sure that the ethics of the thug lawyer you hire to execute the transaction are impeccable
@realDonaldTrump
Donald J. Trump
6 years
What kind of a lawyer would tape a client? So sad! Is this a first, never heard of it before? Why was the tape so abruptly terminated (cut) while I was presumably saying positive things? I hear there are other clients and many reporters that are taped - can this be so? Too bad!
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@ethanjweiss
Ethan J. Weiss
1 year
@bigfatsurprise Nina, are you seriously trying to connect this poor kid's fentanyl addiction and his utterly bleak outlook to the fact that he is eating cereal? Please tell me this is some kind of performance art because otherwise it is pretty freaking gross
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@ethanjweiss
Ethan J. Weiss
6 years
BREAKING: Pretty much all my WTF receptors have been permanently downregulated
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@ethanjweiss
Ethan J. Weiss
5 years
The eggs are definitely the problem...
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@ethanjweiss
Ethan J. Weiss
3 years
Hall of fame level smugness here
@NateSilver538
Nate Silver
3 years
It's also pretty embarrassing for the public health profession that it's largely outsiders like me and @zeynep and @mattyglesias who are **actually looking at the scientific evidence** and pointing out these obvious problems and that there aren't more critiques from within.
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@ethanjweiss
Ethan J. Weiss
4 years
1. Literally nobody recognizes me 2. I was happy to find half of my @OslerResidency intern uniform. Can’t find the short white coat. 3. The mood here in the hospital is good. It’s reassuring 4. Off to round...
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@ethanjweiss
Ethan J. Weiss
4 years
19/ We enrolled/compeletd this trial quickly (about a year) with the incredibly hard work of Dylan and the study team This morning the paper is finally published!
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@ethanjweiss
Ethan J. Weiss
1 year
We should celebrate that more people have solutions that can work for them. Not doing so is the height of arrogance
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@ethanjweiss
Ethan J. Weiss
5 years
The truth about eggs is that there will never be truth about eggs, so either eat them and enjoy them, or don’t eat them and enjoy not eating them. But maybe we can all just stop talking about it like - forever
@JohnSpeakman4
John Speakman
5 years
The truth about eggs and health.... Given the confusion about eggs and health I searched the internet for the definitive answer. here it is.....
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@ethanjweiss
Ethan J. Weiss
4 years
2/ Today we are finally publishing the results of a study on Time Restricted Eating (TRE), which is a form of intermittent fasting. The study is called the TREAT Study. More on that later…
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@ethanjweiss
Ethan J. Weiss
5 years
Not as crowded as intermittent fasting but nearly full room here at the low-carbohydrate nutrition session at #ADA2019 - yes you read that correctly. There is a low-carb session at the ADA
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@ethanjweiss
Ethan J. Weiss
4 years
I've done an OK job staying away from politics recently. Some will say that now is not the time for partisanship. And I disagree strongly. If there is ever a time to highlight the utter incompetence of this foolish blowhard, it is now. We need a leader and we have a fucking clown
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@ethanjweiss
Ethan J. Weiss
4 years
Day 1: Spirit
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@ethanjweiss
Ethan J. Weiss
5 years
Thread: This job is humbling
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@ethanjweiss
Ethan J. Weiss
5 years
Hey Jack, I hate to be this kind of asshole but actually I feel pretty strongly about this topic, so what the hell. In your discussions about "healthspan", did you get a chance to ask Ben about this?
@jack
jack
5 years
Thanks Ben! Great conversation, and appreciate all you do to simplify the mountain of research focused on increasing one’s healthspan! Grateful for you
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@ethanjweiss
Ethan J. Weiss
4 years
An old friend just messaged me to ask me if I was being sarcastic here. I guess if Dr. Fauci is a disaster then almost all of us would also aspire to be such disasters. So yes, in case it is not clear, I am being sarcastic. He is a hero
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@ethanjweiss
Ethan J. Weiss
4 years
On a conference call just now: "If we are accused in a few weeks of overreacting, we will welcome that" Seems right...
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@ethanjweiss
Ethan J. Weiss
4 years
10/ Long story short, Dylan joined the group to lead the TREAT Study. To say he was fundamental in the design, implementation and completion of the study would be a dramatic understatement. He was the study. Also...
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@ethanjweiss
Ethan J. Weiss
1 year
It also seems relatively uncontroversial to acknowledge that medicines are a life-saving solution for those with hypertension who cannot control their blood pressure with lifestyle alone
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@ethanjweiss
Ethan J. Weiss
6 years
I want to tell a two-part story. I'll allow that I have no way of knowing what is "right" here. I just want to share the story. So I have a patient who is in his late 70's. He has extensive CAD with multiple stents and is post-CABG. He first came to see me a few years ago
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@ethanjweiss
Ethan J. Weiss
2 years
Aside from the fact that there is zero evidence that fasting does anything to improve even one meaningful clinical outcome, something I’ve never understood is why you’d need an app to tell you not to eat. Can’t you just not eat and like look at your watch?
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@ethanjweiss
Ethan J. Weiss
7 years
It's almost 9AM and I've not yet had a cup of coffee. This must be what it feels like to be septic
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@ethanjweiss
Ethan J. Weiss
7 years
Somewhere in the "How to handle a press crisis" handbook, there must be a chapter on arguing with celebrities on Twitter
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@ethanjweiss
Ethan J. Weiss
2 years
I had a conversation this week during which I bet someone that I could completely make up a diet and promote it and that it would end up a best seller. Then someone else pointed out that @AlanLevinovitz actually did this…
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@ethanjweiss
Ethan J. Weiss
4 years
I sequenced my genome this morning. I found out that I am homozygous for a loss of function allele in the “I give 2 shits about rockets” gene
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@ethanjweiss
Ethan J. Weiss
5 years
I have added a question that I now ask all new patients when I see them: "What percentage of meals that you eat on a weekly basis do you prepare or are prepared by a family member?" I am not sure what I'll do with it but people seem to like the question and I learn a lot
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@ethanjweiss
Ethan J. Weiss
4 years
20/ What did we find? Well, let’s start with the bottom line. This was a negative study. TRE did not lead to a statistically significant difference in weight loss at 12 weeks. First, the good news. It was relatively easy to comply at least by self-report. So it’s doable
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@ethanjweiss
Ethan J. Weiss
3 years
Admittedly, it’s a small sample size, but 2021 has a very 2020ish feel to it, so far
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@ethanjweiss
Ethan J. Weiss
2 years
When you can get a month of life saving medicine for less than the cost of a single grande latte at Starbucks, you are winning
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@ethanjweiss
Ethan J. Weiss
6 years
July 1, 1998 was my first official day at UCSF when I started as a Cardiology Fellow (in the lab). I was 29 & single & moved to California from Baltimore never expecting I’d still call it home 20 years later. Now this...
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@ethanjweiss
Ethan J. Weiss
7 years
How many times has Obamacare almost died? Someone should sequence its genome or study its microbiome or something
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@ethanjweiss
Ethan J. Weiss
4 years
22/ This is important. If this had been an uncontrolled study, we'd be saying there was a significant decrease in weight. But there was that pesky control arm. We know that people in clinical trials to lose weight no matter what you do. Including the control arm was important
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@ethanjweiss
Ethan J. Weiss
4 years
24/ If you squint, maybe you can convince yourself more people lost weight in the TRE group, but having squint is never a good thing in science
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@ethanjweiss
Ethan J. Weiss
4 years
We are nowhere near out of this, but the news here is not horrible (ok?) - The number of cases in hospitals here seems stable. The surge may yet come but each passing day without it is encouraging - If and when the surge comes, we will be prepared
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@ethanjweiss
Ethan J. Weiss
4 years
30/ 3) focusing just on weight loss may lead one to assume benefit when there could be harm. The lean mass example is a good one. Losing 1 kg of mass =/= a kg of fat. Indeed, if one loses .65 kg of lean mass and only .35 kg fat mass, that is an intervention I’d probably pass on
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@ethanjweiss
Ethan J. Weiss
2 years
Visiting family in NC. Stopped for gas. My children now understand that we do indeed live in a bubble
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@ethanjweiss
Ethan J. Weiss
4 years
More and more patients come in telling me they prefer to take Red Rice Yeast Extract instead of statins
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@ethanjweiss
Ethan J. Weiss
4 years
I've been talking to my friend and colleague here at the UCSF CVRI about Zinc. These are musings and please don't think that I am suggesting people take it. I don't though full disclosure, Bill does...
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@ethanjweiss
Ethan J. Weiss
7 years
@realDonaldTrump They are carrying out a silent and peaceful act that we might choose to reflect on. We could stop and ask why they’re protesting
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@ethanjweiss
Ethan J. Weiss
4 years
Just did my first video visit and I am somewhat stunned to admit that I liked it. I would like to be able to get an ECG and I'm sure it would be nice to have vitals and listen to heart/lungs but really overall I give it a 9/10
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@ethanjweiss
Ethan J. Weiss
4 years
5AM (me to my wife): “We should drink less. Tonight let’s have just one.” Her (to me): “Definitely!” 5PM (me to my wife): “About that drinking thing I said this morning, we should start tomorrow.” Her (to me): “Definitely!”
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@ethanjweiss
Ethan J. Weiss
4 years
And a whole group of people were there to greet us. It was not necessary but also very nice. Thank you @united . It meant a lot
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@ethanjweiss
Ethan J. Weiss
7 years
@realDonaldTrump But our President does not. Instead, he chooses to make a series of cold and calculated statements clearly motivated for political gain
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@ethanjweiss
Ethan J. Weiss
4 years
This was about 12 days before he tested positive. What a sad and unnecessary death
@THEHermanCain
The Cain Gang
4 years
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