Sebastian Caliri @SebastianCaliri Twitter profile

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Sebastian Caliri

4 years

Discourse on healthcare in this country is completely wrong. Everyone is arguing about how to funnel more money into a broken delivery system. Ensuring access for all means addressing the elephant in the room: monopoly, cronyism, and anemic productivity growth in care delivery.

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Sebastian Caliri

@SebastianCaliri

5 months

Typical morning in SF: Vandals smashed a dozen planters in front of a restaurant that hasn’t even opened yet on the Embarcadero. I look forward to patronizing Alora as soon as it opens!

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Sebastian Caliri

@SebastianCaliri

4 months

@garrytan MATH WINS BRUTAL VICTORY

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Sebastian Caliri

@SebastianCaliri

3 years

I am not working out with a mask again. This is stupid.

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Sebastian Caliri

@SebastianCaliri

2 years

@dee_bosa **Confusion reigns at CNBC

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Sebastian Caliri

@SebastianCaliri

3 years

@Scott_Wiener Nothing about this recall is right wing or radical — there are lots of issues that all voters regardless of party line can be upset about from housing to fire management to unemployment fraud. I was proud to vote for you twice, but this is disingenuous. Too bad.

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Sebastian Caliri

@SebastianCaliri

6 months

Nothing better than @8vc decked out for Christmas! Happy holidays from Pier 5 ! 🎄🎅🏻🕎

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Sebastian Caliri

@SebastianCaliri

8 months

@micsolana SF truly crushes 3 areas: 1. Parks 2. Public libraries 3. SFO The people in charge of these should get more responsibilities. Especially whoever runs SFO.

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Sebastian Caliri

@SebastianCaliri

5 months

Just finished filling out my ballot with the help of the ⁦⁦ @GrowSF ⁩ guide. My favorite part was voting in favor of math!

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Sebastian Caliri

@SebastianCaliri

5 months

@coinhunter4life Exactly. I'm so frustrated on behalf of the owners who are taking a risk to bring something nice to the city, for the staff that set up the beautiful patio garden, and for the team that could be getting paid holiday bonuses instead of spending to clean up vandalism.

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Sebastian Caliri

@SebastianCaliri

2 years

Book Review: Where's My Flying Car? ⭐️⭐️⭐️⭐️⭐️ At Yale, smart students stayed away from STEM to pad grades. These people now work in law & nonprofits, & because they can't actually solve any problems (w/ science) they simply say "no" to plastic straws.

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Sebastian Caliri

@SebastianCaliri

2 years

Good public schools create opportunities for all students to reach their fullest potential, agnostic of race, gender, and religious creed 🇺🇸 I am proud to support @AnnforSFboe , @LisaforSFboe , and @LainieforSFboe / @sfguardians — and encourage other SF voters to do the same!

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Sebastian Caliri

@SebastianCaliri

1 month

Yesterday we hosted 100+ AI builders in healthcare at @8vc , with demos from @nkbuduma , @notablehealth , and a 1st look at @anothercohen 's newCo. Bullish for productivity and wrinkle-free skin: an AI agent addressed all his concerns about botox and confirmed his appointment live!

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Sebastian Caliri

@SebastianCaliri

3 years

Heisenberg wrote about uncertainty when he was 26. Watson was 25 and Crick was 36 when they solved the structure of DNA. Youth doesn’t preclude important theorizing and discovery. I’m proud to support @newscienceorg and develop alternative models for funding science.

Alexey Guzey

@alexeyguzey

3 years

5/ 70 years later, the NIH has effectively abdicated its responsibility to the next generation of scientists, allocating 7 (!) times more funding to scientists >65 years old–who would’ve been in mandatory retirement had they been serving in the military–than to those <=35yo

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Sebastian Caliri

@SebastianCaliri

5 months

Nothing we are doing as a society is remotely preparing us for the extreme labor supply / demand mismatch we will face in healthcare in the next decade. If you aren't improving productivity as quickly as you can and scaling as rapidly as possible, you are part of the problem.

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Sebastian Caliri

@SebastianCaliri

10 days

@nikitabier Parts of the economy are captured by and largely accessible to only an academic elite: law, medicine, consulting, gov, media, nonprofits. Entrepreneurship generally + tech specifically sits outside the "prestige economy". The strength of these areas diminishes that elite class.

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Sebastian Caliri

@SebastianCaliri

3 months

@AaronPeskin Great. Let us know when you identify such a leader.

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Sebastian Caliri

@SebastianCaliri

1 year

@GavinNewsom This policy is bad, standardized tests are one of the few ways for disadvantaged students to prove themselves even if wealth can pay for better test prep. Admissions policy becomes even more arbitrary w/o them. CA despises its ambitious. Positively un-American (see Lowell HS).

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Sebastian Caliri

@SebastianCaliri

4 months

PLTR vs. SNOW: the flippening is near!

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Sebastian Caliri

@SebastianCaliri

4 years

It isn’t always obvious from the outside, but monopolistic health systems mean lower wages, lower quality, and a lower standard of living for every American. I am proud to work with @JTLonsdale , @AbeSutton and others at @InstituteCicero to help make healthcare cheaper.

Squawk Box

@SquawkCNBC

4 years

"If you want to attack a monopoly that matters to this country it would be attacking healthcare. That is the place where consumers are suffering," @JTLonsdale . "The guys running the big healthcare companies are not celebrities--they're not Zuckerberg, Bezos, etc."

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Sebastian Caliri

@SebastianCaliri

2 years

Most problems with the US healthcare system, from access to cost, can be traced to poor incentives for productivity improvement. @JTLonsdale and I chat about medicine's lagging productivity as well as: - Psychedelic medicine - The fentanyl epidemic - Obesity And manufacturing!

Joe Lonsdale

@JTLonsdale

2 years

One reason U.S. healthcare is broken: fee-for-service rewards inputs over outcomes. Value-based care [like @cityblockhealth ] realigns incentives. Excited to talk healthcare innovation w/ @8VC Partner @SebastianCaliri on Ep 39:

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Sebastian Caliri

@SebastianCaliri

1 year

If you polled New Yorkers they would overwhelmingly vote for a new Art Deco building instead.

The B1M

@TheB1M

1 year

This 210-metre biology-inspired skyscraper has been imagined for Lower Manhattan - #architecture #construction #skyscraper

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Sebastian Caliri

@SebastianCaliri

1 month

Black pill on technology: Software has done absolutely nothing for productivity in healthcare delivery. Multifactor productivity has actually been declining since at least ~2000: we are actually doing less with more each year.

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Sebastian Caliri

@SebastianCaliri

1 month

AI medical scribes aren’t giving my portfolio companies much contribution margin lift. We can reduce scribe-to-provider staffing ratios a bit (COGS ⬇️) — but it turns out medical scribes do all kinds of jobs beyond basic documentation and the role can’t easily be eliminated.

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Sebastian Caliri

@SebastianCaliri

2 months

So many people have asked to invest in Souvla that the FAQ page specifies that you cannot, in fact, invest in Souvla. Consider that Chipotle is an $88B company. Everyone is talking about AI, but SF is sleeping on the massive opportunity for category-leading Greek food.

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Sebastian Caliri

@SebastianCaliri

1 year

SF should have world-beating public schools! Let's offer 8th grade algebra (or even 7th grade algebra) for students who have the appetite. It would also be fun to see if there are ways for the tech + VC community to help inspire curiosity and build bridges to public schools.

SF Guardians

@sfguardians

1 year

President @KevineBoggess & Superintendent @SFUSD_Supe -- will you & the board prioritize restoring 8th grade algebra so NO CHILD is denied the chance to build a STEM career? Will you help our children by removing the obstacles placed in the way of their educational success? 2/3

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Sebastian Caliri

@SebastianCaliri

1 year

Proud to be a part of this team!!! There are many substantive problems we are excited to solve with entrepreneurs in healthcare, industrials, energy, and more.

Joe Lonsdale

@JTLonsdale

1 year

Today, we announce our 5th @8VC flagship venture fund: 8VC Fund V, with $880 million to back the best entrepreneurs tackling complex problems for our civilization, with innovation and grit. The world is broken. Let's fix it.

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Sebastian Caliri

@SebastianCaliri

5 months

Exciting fact: by 2027, value-based care provider profit pools will still be vastly smaller than chiropractors. There is so much left to build!!!!!

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Sebastian Caliri

@SebastianCaliri

3 years

@ByrneHobart Health IT. Plenty of people try and create capabilities for health systems and then realize over time that most health systems aren't subject to any sort of pressures to offer higher quality or lower cost care and then migrate out into offering services directly and competing.

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Sebastian Caliri

@SebastianCaliri

6 months

It turns out you can build things quickly in healthcare - two years ago Harbor was a concept on Clay’s whiteboard at Dell Med. Congratulations to team @HealthAtHarbor ! We at @8vc are excited to continue the partnership, and are optimistic about the impact we can have ☺️

Dan Primack

@danprimack

6 months

Harbor Health raises $95 million for primary care in Texas

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Sebastian Caliri

@SebastianCaliri

4 months

The flippening has been achieved! 🫡 What a day!

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Sebastian Caliri

@SebastianCaliri

4 months

A bullish sign for the Bay Area: Marin County, CA

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Sebastian Caliri

@SebastianCaliri

8 months

@zck The average family in 17th c Puritan New England had 9 to 10 children. SF is nothing like Puritan New England.

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Sebastian Caliri

@SebastianCaliri

6 months

Accelerate or Die! @8vc

Alex Kolicich

@AlexKolicich

6 months

Just walked into the 8VC office! E/acc accelerate or die

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Sebastian Caliri

@SebastianCaliri

1 year

California’s embrace of clean, green, renewables has been remarkable. A solar panel on every street corner!

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Sebastian Caliri

@SebastianCaliri

11 months

@RichardHanania Medical education could be done in 1/2 the current time. The first two years of med school are a hazing ritual where medical students are ceaselessly quizzed on trivia like the names of the bones in your wrist and Krebs Cycle. Source: left medical school at Stanford after 1 year

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Sebastian Caliri

@SebastianCaliri

3 years

Pharmacists can do more than just dispense medication - let's get the red tape out of the way and empower them to practice at top of license + become fully-fledged members of a care team.

Austin-based startup looks to bring value-based care to pharmacies - MedCity News

Austin-based software startup Docstation is working to make it easier for pharmacists to strike agreements with physicians that would allow them to provide more patient care. It recently raised $3.1...

medcitynews.com

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Sebastian Caliri

@SebastianCaliri

3 months

SaaS is a horseless carriage. It derives from existing processes and ossifies them. There is a lot more value creation in building an automobile.

Palantir

@PalantirTech

3 months

Despite being sold modularity, customers of the software-industrial complex have received fragmentation. The #Palantir Ontology and the OSDK make it possible to defragment the enterprise by integrating isolated components into a holistic system.

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Sebastian Caliri

@SebastianCaliri

3 years

@DavidSacks Proud to work with a team that DIDN'T mindlessly lend money, time, or publicity to such a misguided organization. There are things we can do to create social mobility and build a more compassionate society. Supporting BLM isn't one of them.

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Sebastian Caliri

@SebastianCaliri

11 months

Palantir is an artists' colony: a place where many people discovered & cultivated their unique talents and had immense freedom to use them. It is no wonder that, pound for pound, there is no stronger group of alumni entrepreneurs. Palantir culture reaches far beyond the company.

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Sebastian Caliri

@SebastianCaliri

1 year

Are you a motivated and curious high school student in the Bay Area? Do you know motivated and curious high school students? Join for UATX’s summer high school program! Excited to be taking about the US healthcare system where spending mysteriously goes 📈 and productivity 📉

University of Austin

@uaustinorg

1 year

Our summer high school program is back by popular demand — this time in San Francisco! AI, Plato, data science, American political thought, healthcare & more by great professors and entrepreneurs. July 31-Aug 2. Hurry — applications close July 23.

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Sebastian Caliri

@SebastianCaliri

1 year

Every organization has its own pattern language: nouns, verbs, and syntax and grammar to link them. Palantir will become an era-defining company by rendering these concepts accessible to AI agents, and enabling enterprise-wide human / computer symbiosis faster than any other.

Peter Wilczynski

@petewilz

1 year

@jorgenthoughts In an era of LLMs, it also means that the core concepts your applications depend on will also be legible to language models, and so we can serialize + deserialize the ontology into a dialect of natural language which actually has overlapping terms with the OSDK.

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Sebastian Caliri

@SebastianCaliri

3 years

@arch_crimes You forgot 2017: RETVRN

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Sebastian Caliri

@SebastianCaliri

2 years

There are & will continue to be exciting venture-backed health services businesses in the years ahead. However, these companies must watch KPIs very different from SaaS: clinic or care pod-level EBITDA capacity; paybacks; new EBITDA capacity per $ SG&A burn per yr to name a few.

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Sebastian Caliri

@SebastianCaliri

3 months

@farbood @garrytan These are sick, please bequeath some to 8VC. Will go great with our new flag 💪🏻

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Sebastian Caliri

@SebastianCaliri

3 years

If we don’t build stuff for Medicaid populations then we won’t have better stuff for Medicaid populations. Honored to have ⁦ @iyahromm ⁩ and ⁦ @rebekahgeemd ⁩ with us today at ⁦ @8vc ⁩ to talk about the opportunity. We’re excited to do more for our least well off.

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Sebastian Caliri

@SebastianCaliri

5 months

@EricaJSandberg Yes it is

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Sebastian Caliri

@SebastianCaliri

2 years

Residents are forced into an unnecessarily long program of indentured servitude, disguised as training. The cartel of hospitals w/ residency slots colludes via Match to maintain the system. Lobbying by AAMC and @ahahospitals protects them from antitrust:

Jung v. Association of American Medical Colleges - Wikipedia

en.wikipedia.org

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Sebastian Caliri

@SebastianCaliri

1 year

@RichardHanania @ATabarrok Secular in a sense. I’d say it’s more accurate that they created an entirely new religion — an American civic religion where God bids us life, liberty, and the pursuit of happiness But yeah the foundering fathers were definitely not orthodox Christians in any way, that’s retcon.

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Sebastian Caliri

@SebastianCaliri

3 years

A right to healthcare is a right to expropriation. Reminder that you can want to improve access to healthcare for all Americans without committing the logical error of finding a “right to healthcare”.

President Biden

@POTUS

3 years

Health care should be a right — not a privilege. And with the beginning of the open enrollment period today, we can continue delivering on that promise. Signing up is easy — simply go to and select the plan that works best for you and your family.

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Sebastian Caliri

@SebastianCaliri

4 years

@singareddynm I'd take a step back and say: historically, amateurs and outsiders theorizing and speculating about different areas has been very important for scientific progress.

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Sebastian Caliri

@SebastianCaliri

2 years

Everyone in Silicon Valley knows someone whose life has been made miserable by immigration bureaucracy. Talented new Americans are our lifeblood, and the State Dept insults both them and taxpayers alike. (Think about this next time new power / budget is given to admin agencies)

Joe Lonsdale

@JTLonsdale

2 years

Thread: for 2+ years the State Dept. has been bungling the US visa system. The wait time in New Delhi for a tourist visa is >800 days! Are we supposed to just accept gross government incompetence nowadays? In tomorrow’s @WSJ I argue that we shouldn’t...

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Sebastian Caliri

@SebastianCaliri

7 months

Tired from all the BUILDING happening in SF and NY and ATX? Miami is an excellent place for vacation.

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Sebastian Caliri

@SebastianCaliri

3 years

@urbit is a decentralized internet where no black box algorithms manipulate the information you see, no service provider can sell your data, and no authority can abuse your right to privacy. It is a good time to get on urbit.

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Sebastian Caliri

@SebastianCaliri

3 years

@noampomsky Yeah this is about 20% of the company. I think we are most of the active user base on Goodreads

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Sebastian Caliri

@SebastianCaliri

3 years

@davidasinclair @Levels Where is the good evidence around benefits of stable / low blood sugar levels for populations without a diabetes diagnosis? Lots of good work published for diabetic populations, have been looking for rigorous studies on otherwise healthy populations.

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Sebastian Caliri

@SebastianCaliri

5 months

@drmzio No but there are lots of problems

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Sebastian Caliri

@SebastianCaliri

3 years

Software for our healthcare providers isn't good enough. We are hamstringing our doctors and nurses instead of enabling them. @commurehealth + PatientKeeper accelerates one of the few credible efforts to do better. We're proud to be involved @8vc .

Commure + PatientKeeper: Fixing Fragmentation to Accelerate Innovation Across Healthcare | Commure

Commure has entered into an agreement to acquire PatientKeeper, the first step of a long-term partnership between HCA Healthcare and General Catalyst.

www.commure.com

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Sebastian Caliri

@SebastianCaliri

2 years

Nothing better than ⁦ @8vc ⁩ at Christmastime!

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Sebastian Caliri

@SebastianCaliri

8 months

A couple folks have pointed out that these 3 are among the few departments controlled directly by the SF mayor. The rest are run by unelected and unaccountable commissions. We should make SF’s mayor strong again!

Sebastian Caliri

@SebastianCaliri

8 months

@micsolana SF truly crushes 3 areas: 1. Parks 2. Public libraries 3. SFO The people in charge of these should get more responsibilities. Especially whoever runs SFO.

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Sebastian Caliri

@SebastianCaliri

3 years

@regardthefrost Countless lives would have been saved if you were running FDA.

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Sebastian Caliri

@SebastianCaliri

5 years

@realDonaldTrump I love San Francisco and not sure how much Pelosi has to do with it but can confirm the streets are dirty and we can do better.

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Sebastian Caliri

@SebastianCaliri

1 year

Every serious person should have a Junto: @hyperindexed @dlukeomalley @crystalcultures

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Sebastian Caliri

@SebastianCaliri

4 years

Clinical innovation and technology make it possible to do more with less, and provide a stronger safety net for our least well off. Congratulations to the @cityblockhealth team - @8vc is proud to support you on this important mission.

Cityblock Health

@cityblockhealth

4 years

Today, three years after we launched Cityblock, we are excited to announce $160 million in Series C funding, furthering our mission to radically transform the health of marginalized communities.

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Sebastian Caliri

@SebastianCaliri

5 months

How can you tell a services company is actually tech-enabled? Look for weird invented titles like “care promoter” and “family advocate”. Real tech cultures invent new roles because technology reinvents business process. BETA cookie cutter SaaS just hydrates existing workflow!

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Sebastian Caliri

@SebastianCaliri

3 years

Legalize birthing centers! Lower cost (21% savings) + higher quality (better pt exp, fewer C-sections) than hospital birthing suites for low complexity pregnancy. 10 states have no licensure pathway & more have such complex requirements that few exist.

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Sebastian Caliri

@SebastianCaliri

5 months

@cmwahlqu @MabreyTed DATA ENGINEERS HATE HIM THIS ONE WEIRD TRICK FOR RADICALLY ACCELERATING ETL

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Sebastian Caliri

@SebastianCaliri

2 years

We’re excited to support entrepreneurs using technology to make more stuff! 🇺🇸 @8vc

Aaron Slodov

@aphysicist

2 years

Good morning, we are going to win

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Sebastian Caliri

@SebastianCaliri

3 years

The past year has brought about some dramatic changes. For instance, Julie’s Ultimate was reclassified as medium roast.

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Sebastian Caliri

@SebastianCaliri

3 years

Excited to see more investment in our Medicaid beneficiaries and other underserved populations. Congratulations to the @cityblockhealth team! @8vc

Cityblock Health

@cityblockhealth

3 years

Cityblock’s @toyinajayidoc and @iyahromm spoke with @katiedjennings of @Forbes about our $192M Series C-2 and what it means for the millions of underserved people on Medicaid.

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Sebastian Caliri

@SebastianCaliri

5 months

Another interesting feature of US healthcare is how much of it is private or non-profit. That $366B in annual profit in healthcare services? Less than ~2% of that comes from the biggest publicly-traded names, HCA ($75B market cap) and Tenet ($8B market cap).

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Sebastian Caliri

@SebastianCaliri

5 months

Investors love SaaS but how much real value has it created in comparison to software-enabled businesses like Amazon?

Peter Wilczynski

@petewilz

5 months

When investor demand substitutes for customer demand, there’s almost always a bubble.

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Sebastian Caliri

@SebastianCaliri

3 years

Over 100,000 Americans will die from drug overdose this year, largely from synthetic opioids originating in Chinese state-owned enterprises. Just because media stopped reporting doesn't mean the problem is gone, & doesn't make the CCP any less culpable.

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Sebastian Caliri

@SebastianCaliri

4 years

@regardthefrost @_oumuamua Why is the word "why" used when there is a perfectly good English word to describe the same thing (wherefore)?

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Sebastian Caliri

@SebastianCaliri

5 months

@MabreyTed Ok, but pipeline builder is literally magic!

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Sebastian Caliri

@SebastianCaliri

1 year

Cultural excellence! The average gas station in Italy has fresh-squeezed orange juice, a dozen types of aperitivi, and burr grinders / coffee equipment that you’d find in a high end cafe in the US.

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Sebastian Caliri

@SebastianCaliri

2 years

@alexandrosM Last one is basically this, among the more disappointing episodes. It was weirdly dogmatic and preachy.

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Sebastian Caliri

@SebastianCaliri

3 years

Psychedelic medicine works. I can't wait for us to make these therapies available to more people who would benefit from them. We can do that by gathering more data on safety & efficacy, characterizing the risks & benefits, and continuing to refine dosing / therapy strategy.

Dr. Cameron Maximus🤴🏻 🥷🏻 🧙🏻‍♂️ 🤵‍♂️

@DrCamRx

3 years

Excited to share with all of you our latest episode of the Maximus Podcast with Sebastian Caliri. @SebastianCaliri Sebastian and I discuss many topics including the benefits of ketamine psychotherapy. Watch the full episode on YouTube:

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Sebastian Caliri

@SebastianCaliri

3 years

@Scott_Wiener Here in SF crime keeps getting worse, housing isn’t getting cheaper, taxes are driving away businesses, and fires are about to blanket our city in smoke. National culture wars issues are a distraction — we need your help on these California issues Senator Wiener!

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Sebastian Caliri

@SebastianCaliri

2 years

"[An abundance agenda] harnesses the left’s emphasis on human welfare .. libertarians’ obsession w/ regs to identify places where bad rules get in the way .. and would channel the right’s fixation with greatness to grow what actually makes a nation great"

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Sebastian Caliri

@SebastianCaliri

3 years

Shameful. Monopolistic health systems (many with nonprofit status) drive up prices and drive down wages.

Rachel Cohrs Zhang

@rachelcohrs

3 years

Rod Hochman, American Hospital Association board chair and Providence St. Joseph Health CEO, denies research showing hospital consolidation raises prices raised during a Senate hearing: "We just don't buy the data."

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Sebastian Caliri

@SebastianCaliri

4 months

@razibkhan This is correct. Medical school is 50% useful and 50% elaborate hazing ritual. So if you throw out the hazing ritual, 8 years should easily go to 4. Unfortunately, it seems like competitive residencies are only inflating the time required for medical training.

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Sebastian Caliri

@SebastianCaliri

3 years

Lipid nanoparticle chemists, you're the real MVP.

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Sebastian Caliri

@SebastianCaliri

14 days

A lot of hires are senior but not very good. Other hires are good but not very senior. The former are bad because they misdirect resources and spread bad memes. Seniority is more intuited than taught. But there is huge alpha in training the right people to be senior.

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Sebastian Caliri

@SebastianCaliri

20 days

Epic is often portrayed negatively in the startup / HIT ecosystem. But white pill is that it is one of the most impressive businesses I have ever seen. $5B ARR, $1-2B FCF, 10k+ employees, 36% US EHR market share. Pictured: Deep Space Auditorium. Seats 12,000.

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Sebastian Caliri

@SebastianCaliri

11 months

@JTLonsdale @SenWarren @LindseyGrahamSC @WSJ Recently learned NRC fees for permitting / licensing can exceed $40M-50M(!) for a new nuclear plant. Try starting a nuclear company… Innovation and entrepreneurship are hard enough. Policy that doesn’t acknowledge the *massive* downside of good ideas never tried is bad policy.

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Sebastian Caliri

@SebastianCaliri

3 years

In the US, effective monopsony for our biggest consumers of healthcare (age 65+ population) and excessive regulation slows down innovation and lets Baumol happen. In the absence of Medicare Advantage I wonder if things would be worse.

Balaji

@balajis

3 years

@_dsam3 Baumol’s doesn’t happen by accident. Why have we been able to automate away elevator operators, librarians, switchboard operators, and string quartets (via mp3) but not other service jobs? The answer is typically regulation.

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Sebastian Caliri

@SebastianCaliri

2 years

It was a blunder for policymakers to trash oil & gas over the past ~2 years to drum support for clean energy. Between capital markets and supply chain constraints we can't easily add production. Anecdotally, 12-15 mo lead times currently req'd for drilling & completion supplies.

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Sebastian Caliri

@SebastianCaliri

3 years

@singareddynm @based_patrol +1 - but also Ulysses!

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Sebastian Caliri

@SebastianCaliri

3 years

Wisdom from my @8vc colleague @shohinigupta !

Nikhil Krishnan

@nikillinit

3 years

. @shohinigupta 's idea of a therapy-led primary care seems more and more prescient - you could start a continuous relationship with a therapist and eventually transition them to a PCP when having a longitudinal relationship with the PCP starts mattering

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Sebastian Caliri

@SebastianCaliri

2 years

Exciting result in JAMA: Two psilocybin-assisted therapy sessions took patients from 5+ alcoholic drinks a day to ~1 w/ nearly a year follow up. Alcohol use (and many forms of substance use) can be tough to treat. Psychedelics continue to show promise.

Psilocybin-Assisted Psychotherapy vs Placebo in the Treatment of Adult Patients With Alcohol Use...

This randomized clinical trial evaluates the combination of psychotherapy with psilocybin vs active placebo in patients with alcohol use disorder.

jamanetwork.com

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Sebastian Caliri

@SebastianCaliri

3 years

@JohnathanBi Sorry, I think you accidently put "trivia" where you meant to write "chess"

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Sebastian Caliri

@SebastianCaliri

4 years

@soonaorlater Revolt of the Public by Martin Gurri

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Sebastian Caliri

@SebastianCaliri

5 years

@EmbarcaderoSafe @LondonBreed The navigation center is not going to ruin the park. The real thing we should be outraged by here is that a park took $26M and 15 years to complete.

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Sebastian Caliri

@SebastianCaliri

3 months

@mrexits @JoshuaSteinman Fracking and horizontal drilling are a miracle. We have the best oilmen on the planet.

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Sebastian Caliri

@SebastianCaliri

3 years

@calleymeans Incredible result! MDMA, ketamine, psilocybin, and ibogaine work. Love the steady drumbeat of high quality safety and outcomes data.

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Sebastian Caliri

@SebastianCaliri

3 years

@nikillinit What if primary care should have been the real risk-bearing entity all along?

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Sebastian Caliri

@SebastianCaliri

6 months

@MikeSlagh Proud to see us on the list 🫡🇺🇸 Working with military veterans at Palantir was a privilege too!

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Sebastian Caliri

@SebastianCaliri

2 years

@nikillinit Agree

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Sebastian Caliri

@SebastianCaliri

2 years

Dell Medical School in Austin has been a leader in training physicians for a future of value-based care. Super excited to see Dean @ClayJohnstonMD start to bring that vision to life!

Clay Johnston

@ClayJohnstonMD

2 years

Are you interested in joining me and a superstar team to build an entirely new health system, launching first in Austin, TX? While still in stealth, we are hiring in several areas and especially need primary care. Connect through

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