Evan Zhao @EvanZhao6 Twitter profile | Pikagi

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Evan Zhao

@EvanZhao6

1,145

Followers

520

Following

75

Media

1,557

Statuses

Best friend of Miaomiao. Just my thoughts on science, biotech, startups.

Boston, MA

Joined March 2018

Don't wanna be here? Send us removal request.

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@EvanZhao6

Evan Zhao

1 year

The @revela team is excited to announce that we are joining ODDITY! We've had a crazy up and down experience these last two years and couldn't be more thrilled to be joining such an amazing team to continue disrupting the beauty and wellness industry with biotechnology.

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@EvanZhao6

Evan Zhao

1 year

@finejuli Isn’t it that the airplane companies want the first class people to board first so you have to walk by them and feel jealousy?

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@EvanZhao6

Evan Zhao

1 year

@JoshuaPHilll Feel like the vibe definitely changes if they don’t murder people…

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@EvanZhao6

Evan Zhao

1 year

@ElonBachman If you’re paying more than $4.99 for a large rotisserie chicken I assume you hate yourself. Costco master race.

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@EvanZhao6

Evan Zhao

2 months

@isaachasson I don’t think people ever actually thought they provided real value. It’s mostly to help with liability for any decisions. “McKinsey told me to do it”

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@EvanZhao6

Evan Zhao

1 year

@Kidfears99 Bro but they made some minor changes to it extending their patent protection because “innovation”. You should feel blessed to be able to use drugs that are 0.1% more effective

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@EvanZhao6

Evan Zhao

1 year

In a stunning @Nature paper, by studying hairy moles, this team found that the zombie cells everyone thinks are responsible for aging actually might have hair growth promotion effects. All of these drugs against senescence might cause baldness…

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Signalling by senescent melanocytes hyperactivates hair growth

Nature - Senescent melanocytes of skin nevi drive hyperactivation of hair growth through the signalling factor SPP1.

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@EvanZhao6

Evan Zhao

1 year

@sivomengro

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@EvanZhao6

Evan Zhao

1 year

@peterrhague Scientists refusing to explain things to everyday people is exactly what makes the public distrust science. A lot posture for status, money, etc. It’s sickening.

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@EvanZhao6

Evan Zhao

11 months

@unusual_whales I for one welcome the suing of Harvard by all groups

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@EvanZhao6

Evan Zhao

1 year

Redbull now makes you live longer? And the paper is in Science I guess energy drinks might be the way.

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Taurine deficiency as a driver of aging

Taurine supplementation extends healthy lifespan in worms, rodents, and non-human primates.

www.science.org

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@EvanZhao6

Evan Zhao

11 months

@VCBrags Tbh offering 7.5% of the money straight up for consulting is pretty absurd.

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@EvanZhao6

Evan Zhao

2 years

@sweatystartup Anyone with software engineering friends knows they brag about only working 3 hours a day while making $300K+. It’s time that gets cleaned up.

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@EvanZhao6

Evan Zhao

11 months

@Austen Phenomenal super villain origin story

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@EvanZhao6

Evan Zhao

3 years

@angelosmao and I are excited to share our new story out in @NatureBiotech today! Under the tutelage of the amazing and supportive Professor James J. Collins, we introduce a new wrinkle for mammalian cell synthetic biology.

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@EvanZhao6

Evan Zhao

5 months

@bryce Or…it could be that it’s hard to record layoffs videos in the office

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@EvanZhao6

Evan Zhao

2 months

@buccocapital I’m pretty sure this is a core case in business school

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@EvanZhao6

Evan Zhao

11 months

@CarlZha I’m sure their personalities are just not very good though (at least to Harvard)

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@EvanZhao6

Evan Zhao

11 months

@nikitabier I feel like downfall of threads will actually be it’s connection to insta. Don’t think long term people will want to follow spicy content on an app where their faces are.

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@EvanZhao6

Evan Zhao

2 months

@Jess_Osterhout Professors all have favorite students. Sometimes without any real reason. Find a PI who will be behind you 100%. They’ll edit your papers faster, fight for better publications, and make your life easier.

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@EvanZhao6

Evan Zhao

1 year

@HenrickTheBull @ElonBachman I’m sorry for your loss

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@EvanZhao6

Evan Zhao

1 year

Advancing RNA-sensing from Jim Collins’ lab! Congratulations to all of the amazing authors.

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Autocatalytic base editing for RNA-responsive translational control

Nature Communications - Genetic circuits that control transgene expression in response to pre-defined transcriptional cues would enable the development of smart therapeutics. Here the authors...

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@EvanZhao6

Evan Zhao

10 months

@browserdotsys Martin’s take is like 90% of why people quit academia 😂

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@EvanZhao6

Evan Zhao

10 months

@typesfast I am exceedingly worried that you tweeted this during our meeting 😅

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@EvanZhao6

Evan Zhao

2 years

@lucy_guo Saw the anger responses to your 11pm thing and was thinking”wow none of these people get what she means.” As a founder, we don’t need people working 17 hours a day, but it’s great to see people excited enough to answer an 11pm message. It’s the excitement

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@EvanZhao6

Evan Zhao

11 months

@kennymxu @CNN Damn are we a spicy race now? I thought we were only good at being the workhorses and didn’t have leadership qualities? Thanks for fighting man! They have to know we aren’t just sitting down anymore.

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@EvanZhao6

Evan Zhao

5 months

@chinesegon I’m like fairly certain these are different Kevin Changs

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@EvanZhao6

Evan Zhao

2 months

@unusual_whales The best sign to never ever hire McKinsey to solve your company’s problems

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@EvanZhao6

Evan Zhao

9 months

@AJA_Cortes Bro are you telling me the influencer-fueled brand was indeed not following any science at all? Completely unexpected!

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@EvanZhao6

Evan Zhao

11 months

@JChanKraushar @CARM1Monoxide I just really hate the whole personality score thing. I really don’t care what the goal was. That was racist and should never be targeted. We shouldn’t have to just sit here and take it.

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@EvanZhao6

Evan Zhao

3 years

Yeah your fellowship is cool but do you have custom m&ms? @SchmidtFellows

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@EvanZhao6

Evan Zhao

1 year

@protosphinx PSA: undergrads don’t represent the work of an entire institute. This was not properly reviewed and wasn’t properly supervised. This would be akin to saying the kids brewing meth out of cough syrup or growing pot are chemists at the university.

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@EvanZhao6

Evan Zhao

10 months

@typesfast PSA McKinsey invented a fake pain scale so Purdue Pharma could peddle more opiates. People need to go to jail for this shit

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@EvanZhao6

Evan Zhao

11 months

@joncoopertweets @CARM1Monoxide Yes yes but what if we removed both ladders though

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@EvanZhao6

Evan Zhao

1 year

@SheluyangPeng @RichardHanania We’re only a part of the narrative when we are useful not when they have to share the pay… very unfortunate.

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@EvanZhao6

Evan Zhao

2 years

@johnhfio 2016 summer with Pokémon Go rip

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@EvanZhao6

Evan Zhao

3 years

We just signed up for @MainStreet and I have never been more ecstatic about a business model or idea. This is so much better than Geico - 15 minutes saves you A LOT of money.

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@EvanZhao6

Evan Zhao

3 months

@PookiesParadise The biggest con is they started a 2 for $3.99 deal acting like this shit wasn’t $1 5 years ago.

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@EvanZhao6

Evan Zhao

4 years

Need to finely tune protein expression under iptg control? Use the newly published light-controlled lac operon in @nchembio ! Congratulations to @SincerelyMakoto for such a cool piece of work!

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Optogenetic control of the lac operon for bacterial chemical and protein production

Nature Chemical Biology - Reengineering of the lac operon in E. coli from a ligand-inducible to a blue-light-regulated gene expression system facilitates optogenetic control of biotechnological...

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@EvanZhao6

Evan Zhao

1 year

And then they came for the consultants

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ChatBA: Generative AI for Slides ✨

Instantly create slide decks using ChatBA

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@EvanZhao6

Evan Zhao

1 year

@Codie_Sanchez People were making fun of the conspiracy theorists for worrying about this happening lol

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@EvanZhao6

Evan Zhao

1 year

@_Slothrop_ @Kidfears99 Ok but they named it a cooler name though

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@EvanZhao6

Evan Zhao

11 months

what the fuck evan doing? his best

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@EvanZhao6

Evan Zhao

3 months

Excited to share Pacagen with the world! By taking protein therapeutics and repurposing them for neutralizing the allergens in the air and on surfaces, Pacagen is creating safe, effective allergen neutralizing sprays.

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Backed by biotechnology, Pacagen's sprays neutralize cat allergens safely and more effectively than any other product. Live without allergy anxiety now!

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@EvanZhao6

Evan Zhao

7 months

@HarryStebbings This isn’t just buying stock though - Deckers put in more than a decade of work for both of those. Truth is those companies may have gone bankrupt if it wasn’t for this acquisition.

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@EvanZhao6

Evan Zhao

3 years

Excited to share the last paper from my PhD! Co-led by @SincerelyMakoto here we tried to get around the light penetration for giant fermenters problem by making super sensitive opto circuits!

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Optogenetic Amplification Circuits for Light-Induced Metabolic Control

Dynamic control of microbial metabolism is an effective strategy to improve chemical production in fermentations. While dynamic control is most often implemented using chemical inducers, optogenetics...

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@EvanZhao6

Evan Zhao

2 years

My favorite part of being a @SchmidtFellows senior fellow is the amazing team really asks questions like”what would make you come back?” after throwing incredible gatherings. What a pleasure it was to see everyone!

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@EvanZhao6

Evan Zhao

1 year

@roshanpateI Wait C-suite people are getting paid a lot at startups? I’ve been playing this game incorrectly

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@EvanZhao6

Evan Zhao

1 year

@buccocapital The pentagon

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@EvanZhao6

Evan Zhao

10 months

@tobinjstone

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@EvanZhao6

Evan Zhao

4 years

Hope everyone had a good thanksgiving! Some of my Ph.D. work was just published and I wanted to share it. Playing around with transcription factor stability to build better optogenetic circuits! Thanks to @SincerelyMakoto for helping me get this out!

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Design and Characterization of Rapid Optogenetic Circuits for Dynamic Control in Yeast Metabolic...

The use of optogenetics in metabolic engineering for light-controlled microbial chemical production raises the prospect of utilizing control and optimization techniques routinely deployed in tradit...

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@EvanZhao6

Evan Zhao

10 months

PSA synthetic biology (the newly rebranded metabolic engineering) is very hard. Amyris is a trailblazer for this space. Sad to see this.

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Biotech Company Amyris Files for Bankruptcy

Synthetic biotechnology company Amyris filed for Chapter 11 bankruptcy protection as it restructures, leading its share price to drop more than 70% in early trading Thursday.

www.investopedia.com

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@EvanZhao6

Evan Zhao

2 years

So…this morning we found out that our @Meta ads account was hacked and someone spent $5k in 12 hours on…advertising a video of…wait for it, roasting an unpeeled banana over a stove flame and then dipping it in ice. What is life.

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@EvanZhao6

Evan Zhao

8 months

@samaberman @Cornell DEI advocates be like

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@EvanZhao6

Evan Zhao

2 years

@liron @a16z @Accel @paradigm But…isn’t like 99% of crypto and web3 a Ponzi scheme? What are these people with billion dollar crypto funds supposed to do, not con people out of money?

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@EvanZhao6

Evan Zhao

7 months

@typesfast 100% of people who drink dihydrogen monoxide die

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@EvanZhao6

Evan Zhao

1 year

@anothercohen Please don’t call Dunkin a bagel chain. It’s disgraceful.

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@EvanZhao6

Evan Zhao

2 years

Excited to share our funding announcement for @getrevela ! Want to thank Maki VC and Montage Ventures for leading our round and supporting us on our journey. Shoutout to our other supporters that I can’t find twitters for.

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@EvanZhao6

Evan Zhao

11 months

@blader In two months people will realize that Twitter was about being kind of separate from your actual friends from facebook and insta and threads will be google+ 2.0

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@EvanZhao6

Evan Zhao

1 year

@MorningBrew Cambridge and affordable should really not be in the same sentence

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@EvanZhao6

Evan Zhao

4 years

Excited about a pair of papers that I had the pleasure of working on coming out today! How to make protein binders light switchable!

Development of light-responsive protein binding in the monobody non-immunoglobulin scaffold

Nature Communications - The ability to reversibly control monobody binding affinity would find use in biotechnology and research applications. Here the authors fuse the light-sensitive AsLOV2...

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@EvanZhao6

Evan Zhao

2 years

Fighting COVID but my wife’s been leaving me food outside the door like I’m a troll and I find that both heartwarming and hilarious at the same time so I got that going for me XD

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@EvanZhao6

Evan Zhao

1 year

Congrats to the new class! May all of your gels have bands and all of your graphs have peaks :)

@SchmidtFellows

Schmidt Science Fellows

@SchmidtFellows

1 year

We are thrilled to announce the 2023 cohort of Schmidt Science Fellows - @SchmidtFutures @rhodes_trust - 32 new Fellows will harness interdisciplinary science to make a positive impact on the world.

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Evan Zhao

1 year

@VCBrags How about the dude giving founders advice when he blew tens of millions from his fund on a drone startup that somehow spent it all in 2 years.

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@EvanZhao6

Evan Zhao

3 months

@DrSynbio Bro the current debate is on if meta and tiktok is using our “data” against us. And people thought the vaccines were microchipping us. How do you think literally all genetic info sounds to the US population

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@EvanZhao6

Evan Zhao

1 year

@buccocapital Chamath: spacs are back babyyyyy

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@EvanZhao6

Evan Zhao

3 years

The key word here is UNCAPPED. That’s how much they believe in this program. Congrats to @MichaelRetchin and the team on the program launch!

@MichaelRetchin

Michael Retchin

@MichaelRetchin

3 years

Incredibly excited to announce this @NucleateHQ $1.5M funding award today. Here's what it means for the next generation of biotech founders. 1/5

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@EvanZhao6

Evan Zhao

4 years

Excited to announce that I have received the Schmidt Science Fellowship.

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Eric and Wendy Schmidt Announce 2020 Schmidt Science Fellows - Schmidt Science Fellows

schmidtsciencefellows.org

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@EvanZhao6

Evan Zhao

1 year

I will be leading the development of Oddity Labs in Boston as Oddity's new Chief Science Officer. Forward! .

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ODDITY Invests $100M to Bring Pharma’s AI Based Molecule Discovery Technology to Beauty and...

ODDITY, the consumer technology platform built to transform the global beauty and wellness market, today announces the $76M acquisition of Boston-base

www.businesswire.com

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@EvanZhao6

Evan Zhao

11 months

@micsolana Is threads already dying lol

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@EvanZhao6

Evan Zhao

4 years

Excited to share this paper! How to train your protein to bind based on light condition with up to 150 fold changes in Kd. Hint: give it a lot of LOV :).

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Light-responsive monobodies for dynamic control of customizable protein binding

Customizable, high affinity protein-protein interactions, such as those mediated by antibodies and antibody-like molecules, are invaluable to basic and applied research and have become pillars for...

www.biorxiv.org

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@EvanZhao6

Evan Zhao

1 year

Fucking legend - giving Asian American founders a real role model since I was born.

@ecommerceshares

Wasteland Capital

@ecommerceshares

1 year

Jensen Huang co-founded $NVDA 30 years ago, in Apr-1993, and after 30 years he’s still the CEO. The stock is up 930x since its 1999 IPO. Jensen came to the US as a 9yo, has a BS from Oregon State (where he met his wife, Lori) & an MS from Stanford. He’s worth $38bn. G.O.A.T.🙇‍♂️

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@EvanZhao6

Evan Zhao

4 years

If my kitten can survive with a cone of shame on, I think people can survive wearing a facemask.

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@EvanZhao6

Evan Zhao

3 years

Excited to start as a Venture Partner at Conscience VC. Please send any cool biotech founders over. Miaomiao is excited to hear about all of your amazing ideas!

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@EvanZhao6

Evan Zhao

1 year

Congrats to the whole team for making it into this! On a side note, Glass Onion has ruined the term disrupters for me.

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TIME100 Most Influential Companies 2023: Oddity

Find out why Oddity is on the list

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@EvanZhao6

Evan Zhao

3 years

Finally have our product and doing the best photoshoots.

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@EvanZhao6

Evan Zhao

2 months

@DalalSci Paying it forward because not everything is about output!!!!!!!??????

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@EvanZhao6

Evan Zhao

2 years

Congratulations to Andres and team on this amazing work!

An engineered live biotherapeutic for the prevention of antibiotic-induced dysbiosis

Nature Biomedical Engineering - A strain of Lactococcus lactis engineered to altruistically degrade β-lactam antibiotics through the secretion and extracellular assembly of a heterodimeric...

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@EvanZhao6

Evan Zhao

11 months

People don’t bring this up often enough but having grandparents who are unconditionally proud of you is the biggest blessing. “I made the yeast respond to light today.” My grandparents who fucking fought in wars for me to do this:

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@EvanZhao6

Evan Zhao

1 year

@toomanyspectra “NIH standard”

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@EvanZhao6

Evan Zhao

30 days

@JohnSmi17828195 Damn I fucking love the shade to Cornell.

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@EvanZhao6

Evan Zhao

4 years

Wait this is so cool! I'm sure design isn't trivial but this could be huge for metabolic engineering!

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De novo design of modular and tunable allosteric biosensors

Naturally occurring allosteric protein switches have been repurposed for developing novel biosensors and reporters for cellular and clinical applications [1][1], but the number of such switches is...

www.biorxiv.org

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@EvanZhao6

Evan Zhao

1 year

@HotForMoot

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@EvanZhao6

Evan Zhao

2 years

@heyecs Can’t figure out if this is about Neumann or the Bolt guy or the Fast guy

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@EvanZhao6

Evan Zhao

3 years

Merry Christmas from a fancy kitty

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@EvanZhao6

Evan Zhao

3 years

@WillManidis How could you say something so controversial yet so brave

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@EvanZhao6

Evan Zhao

1 year

@WillManidis It’s more that their attitude that they need a special term talks a lot about how the relationship will be. Never work with VCs who are going to cause trouble - special terms are indicative of this

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@EvanZhao6

Evan Zhao

11 months

@TrungTPhan Wow did some pickle ball player sleep with her husband or something - so angry

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Evan Zhao

21 days

@jefielding Have they tried hiring McKinsey to tell them to just increase revenues and cut costs?

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Evan Zhao

11 months

@stephmui You forgot “he will randomly send you articles about mild competitors and quotes from VC thoughtbois”

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@EvanZhao6

Evan Zhao

11 months

@leadpacer I bet his skincare brand is amazing

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@EvanZhao6

Evan Zhao

2 years

I don’t get a bunch of likes but every once in a while someone I think of as a mentor and role model likes my stuff and really that’s all that I need to keep charging forward. It’s the little things.

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@EvanZhao6

Evan Zhao

2 years

Don’t see enough academics posting about the shootings and that’s too bad because it falls right into the “scientists should just do science” BS. Scientists could make even greater impact if we were active in politics. Crispr is great but so is nondead kids

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@EvanZhao6

Evan Zhao

1 year

@HarryStebbings I can tell everyone from experience that no one flinches at high valuations if you have a good company but everyone indexes on lower valuations for future rounds. Founders - as long as you stay firm on issues regarding control, get the highest valuations possible

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@EvanZhao6

Evan Zhao

2 years

@typesfaster Waiting for bolt documentary starring Zac Efron

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Evan Zhao

11 months

@rod_mallo @VCBrags Honestly not sure what you expected when you posted this lol

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@EvanZhao6

Evan Zhao

3 years

Super pumped to announce @getrevela today! We’ve been working hard to deliver the next generation of consumer products and would love your support!

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@EvanZhao6

Evan Zhao

11 months

@pataguccigoon Is this the dude Elon was bullying lol. Apparently he deserved it

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@EvanZhao6

Evan Zhao

3 years

A nice review on synthetic biology in the clinic by my good friend Xiao! Happy reading!

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@EvanZhao6

Evan Zhao

2 months

@eyeslasho Ah yes glass ceiling is measured by median where outliers (aka ceilings) would be completely accounted for.

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