Update on our
#COVID19
novel antibody program: We’ve identified hundreds of virus-neutralizing antibodies from our VelocImmune technology and are now selecting the top candidates for clinical testing. Learn more:
How do we combat bullying in the
#AtopicDermatitis
(AD) community? ‘Agents of Change’ AD Challenge steering committee member Africa Luca de Tena Smith says creativity is key. Learn more about the initiative and the 2019 grant recipients at . CC:
@Sanofi
The FDA has issued an Emergency Use Authorization for our investigational antibody cocktail to treat mild to moderate
#COVID19
in certain high-risk patients 12 years and older. Learn more:
Congrats
@pfizer
&
@BioNTech_Group
on their
#COVID19
vaccine data announced today. We applaud this important scientific progress, as we all work tirelessly to combat this unprecedented pandemic.
Announcing positive data from 524 additional non-hospitalized
#COVID19
patients in ongoing P2/3 study of Regeneron’s investigational antibody cocktail:
@TimOBrien
Hi
@TimOBrien
- please know that the U.S. government has made our investigational antibody cocktail for
#COVID19
available for free to patients who qualify under Emergency Use Authorization parameters (just like the vaccines are). More info here:
8) After all the hard work, the most important message we want to share is to please get vaccinated – but if you get sick and qualify under the FDA’s emergency authorization, then get TREATED. Find sites here:
#ASCO2021
is expected to provide new insights on advanced
#NonSmallCellLungCancer
(
#NSCLC
). When it comes to the latest research, which of the below topics interests you the most?
#COVID19
program update: We have moved our top SARS-CoV-2-neutralizing antibodies into preclinical- and clinical-scale cell production lines & remain on track to have supply available for clinical studies in June. Read on:
#Multiplemyeloma
predominantly affects older individuals, so understanding comorbidities to optimally manage the disease is critical. This
#ASCO22
we are sharing real-world findings on the prevalence of ocular comorbidities in patients with MM. Learn more:
We are continuing our research with bispecific antibodies. Learn more about our ongoing clinical trial evaluating our investigational bispecific antibody in patients with metastatic castration resistant prostate cancer:
Despite increasing advancements in
#MultipleMyeloma
research, available therapeutic options can lead to high healthcare costs and poor outcomes for patients. We’re presenting data on real-world outcomes in RRMM at
#ASCO22
. Learn more:
New
#RegeneronPerspectives
: Niall O’Leary, VP and Site Head of IOPS in Ireland, discusses the importance of fostering an environment that is focused on shared values between the U.S. and Ireland teams.
We have initiated a Phase 3 prevention trial for our investigational
#COVID19
dual-antibody medicine in collaboration with
@NIAIDNews
(a part of
@NIH
). Read more:
Today, we announce the initiation of clinical trials for our investigational anti-viral antibody cocktail for the treatment and prevention of COVID-19:
#Breaking
: The FDA has approved our novel anti-viral
#antibody
medicine for Zaire ebolavirus in adult and pediatric patients.
#Ebola
Read the full announcement:
Thank you to all the doctors, scientists and others on the front lines who are working tirelessly to help those in need today, and every day.
#NationalDoctorsDay
We're at
#EADV2018
w/
@SanofiGenzyme
discussing the latest research in
#atopicdermatitis
care. While AD may be visible on the skin, its impact goes much further. It's a chronic immune disease with the potential for debilitating effects on quality of life.
Following the EUA of our
#antibody
cocktail for
#COVID19
, our Founder & CEO Len Schleifer reflects on how we got here and what’s still ahead for our team in a
#RegeneronPerspectives
blog.
Reminder: Our investigational antibody cocktail for
#COVID19
is FREE to patients who qualify under the Emergency Use Authorization parameters (just like the vaccines are)
14) Thanks for reading, & for taking a minute to learn more about Regeneron beyond the memes! Here are a few other things – besides our COVID-19 efforts – that we were particularly proud of this year.
Announcing additional positive results from our clinical trial evaluating a single dose of our investigational antibody cocktail to prevent
#COVID19
in uninfected people over an 8-month period.
Congratulations
@pfizer
and
@BioNTech_Group
for shipping out the first doses of the
#coronavirus
vaccine across the U.S. We celebrate this important milestone in combating the pandemic, as we continue to work together on the safe development of treatments and vaccines.
We’re presenting information at
#ASCO22
on the design of our clinical trial of investigational agents in patients with MET-overexpressing
#NSCLC
, a patient population in-need of therapeutic options. Read more about the trial in progress here:
At Regeneron, we’re fusing biological expertise and technological innovation with the goal of transforming the treatment of difficult-to-treat forms of
#cancer
. Watch the video to see our progress over the past 30 years.
#ASH20
Our oncology researchers are exploring the potential of bispecific
#antibodies
to stretch the boundaries of the immunotherapy revolution. Read more in a recent
#RegeneronPerspectives
blog.
#ASH20
We're focused on exploring ways to help children with uncontrolled
#asthma
– a disease with a significant impact on everyday life. Learn more about asthma and type 2 inflammation:
We quickly determined a formula for VTM to meet NYS-specs & our colleagues volunteered to make/package it over weekends/late nights; 100K made so far, with 500K total to be delivered to NYS, a $1M in-kind donation of supplies & labor
#COVID19
news: Our investigational antibody cocktail was shown in vitro to successfully neutralize
#SARSCoV2
variants first identified in the UK and South Africa.
@Columbia
Read more:
No attachment issues here. This Valentine’s Day, we’re admiring antibodies that bind tightly to the targets they love, even withstanding the variants that come their way. Check out our work in Ebola, which is the cover feature in Cell Host & Microbe.
@cellhostmicrobe
13) We’re a group of people working as hard as we possibly can to fight this terrible & disruptive disease. It’s been an unexpected & challenging year for us all, but we’re optimistic about what we can do by harnessing the power of science.
Bispecific
#antibody
therapies have the potential to transform cancer treatment. Drs. Israel Lowy & Andres Sirulnik discuss how we’re stretching the boundaries of
#immunotherapy
innovation in our latest
#RegeneronPerspectives
blog.
#DYK
: anti-viral antibody medicines mimic the natural defenses and pathways of the immune system. Find out how they could serve as an important bridge to a vaccine:
Congrats to the 2020
#RegeneronSTS
top winner, Lillian Petersen, for her exceptional invention to predict crop yield! The future of
#science
is very bright thanks to Lillian and the other talented finalists. For more: CC:
@Society4Science
.🏅
We’re so proud – Regeneron is once again
#1
on
@sciencemagazine
’s annual survey of Top Biopharma Employers! Thanks to our inspiring team who are using
#science
to create a healthier future.
#SCTopEmployer
Producing our
#antibody
medicines is a complex and time-intensive process. We break down how our
#RegeneronIOPS
team turns cells into life-changing medicines using the power of
#science
.
We’re announcing the first clinical and virologic results for our investigational antibody cocktail in hospitalized patients with
#COVID19
. Learn more:
3) Our investigational antibody combination therapy (known as ‘REGN-COV2’) is currently being tested in clinical trials. It was invented this year using our proprietary technologies that were developed over the course of 30 years.
A recent global study showed 82% of adults with
#atopicdermatitis
who are receiving immunosuppressants also have at least one other atopic condition. We're improving clinical understanding of these diseases to better inform how they may be treated.
#WCD2019
5) We did not use human stem cells or human embryonic stem cells in our COVID-19 program. Like many other science-focused organizations, we do use these tools in a responsible & limited manner for certain early research. More here:
When you recover from an
#infection
, you are believed to acquire some lasting immunity against that disease through protective antibodies and immune system memory. More on the important role of adaptive immunity:
Our CSO George Yancopoulos discussed on
@CNNi
how we’re applying lessons from our
#Ebola
research to finding a potential medicine for
#COVID19
. Watch via w/
@jchatterleyCNN
#BREAKING
: The U.S. FDA has approved our treatment for wet age-related macular degeneration, diabetic macular edema, and diabetic retinopathy. Learn more about the
#FDAapproval
and our ongoing commitment to those impacted by these
#RetinalDiseases
:
With
@Society4Science
, we’re introducing the 2022
#RegeneronSTS
finalists!🙌 These 40 bright, young scientists are using
#science
and technology to explore solutions to society’s most complex challenges, including
#COVID19
and climate change.
2) Regeneron is the name of our company – we make many different medicines for many serious diseases & have been around for 30+ years. We are a group of about 9K people, many of us scientists, MDs and/or engineers. More here:
At
#2020GGSummit
, Scott Mellis, MD, PhD, VP of Early Clinical Dev, Rare Diseases, joined a virtual panel discussion on the importance of early patient input in the preclinical development process. Learn about our research areas:
Meet the 2021
#RegeneronSTS
finalists! 👏 These 40 bright young scientists are using science and technology to address some of society’s most complex challenges from clean water to infectious diseases like
#COVID19
. Learn more:
@Society4Science
We’re presenting our latest research in chronic, inflammatory diseases, including asthma, eosinophilic esophagitis, chronic rhinosinusitis with nasal polyps and chronic spontaneous urticaria, at
#AAAAI23
. Explore the data:
@Sanofi
Our IOPS team is also supporting manufacturing of our investigational COVID-19 treatments. Learn more about our COVID-19 research and philanthropic efforts here
#BREAKING
In the largest sequencing study to date to better understand how genetic mutations can cause or prevent liver disease,
@RegeneronDNA
uncovered rare genetic mutations in the CIDEB gene associated with protection from nonalcoholic liver disease and nonalcoholic cirrhosis.
8) After all the hard work, the most important message we want to share is to please get vaccinated – but if you get sick and qualify under the FDA’s emergency authorization, then get TREATED. Find sites here:
Thank you
@NYGovCuomo
for recognizing the efforts of our
#Regeneron
team – in New York and beyond – as we work to deliver new medicines to people in need.
T-cells need two signals to fully activate. But cancer cells can use the PD-1 pathway to inhibit the second signal and suppress T-cell activation. Watch how – and learn why we are investigating potential combination treatments of a PD- 1 inhibitor and CD28
#bispecifics
.
A reduction in overall infections was seen within the first week, with 100% prevention of symptomatic infections. Confirmatory Phase 3 trial results expected in early second quarter.