Using genome engineering to solve humanity’s greatest problems in health, climate & sustainable agriculture. Partnership between
@UCBerkeley
and
@UCSF
.
#CRISPR
Introducing CRISPRpedia – our new, free online textbook for everything CRISPR! Learn (& teach) about
#CRISPR
from its role in nature to development of the genome editing tool, to applications in research, medicine & agriculture. Check it out!
#STEMEd
"I'm always excited about doing science because I love the people I work with and I love the discoveries." – Jennifer Doudna, live (on Zoom) from our
@UCBerkeley
celebration! 🎉
"You were always a star... The only thing better winning the
#NobelPrize
yourself is having one of your former students win it!" – Jack Szostak, Jennifer's mentor for her Ph.D. work
@Harvard
A new review from Jennifer Doudna (
@doudna_lab
) & Joy Wang in
@ScienceMagazine
takes us through the last ten years of
#CRISPR
– and what to expect in the next ten:
We are launching a
#COVID19
diagnostic testing lab on
@UCBerkeley
campus. Volunteer scientists will use robotics to process patient samples, with a turnaround of <24 hours from initial swab to patient getting result.
Learn more:
We are working as hard as possible to establish clinical
#COVID19
testing capability at
@UCBerkeley
campus.
We will update this page often to ask for reagents, equipment, and volunteers:
Please RT and share with Bay Area researchers!
The
@igisci
at
#Cal
@UCBerkeley
working towards establishing CLIA-grade testing capability on campus. We have made strong progress, but the following personnel and hardware could accelerate the effort further.
"Getting girls into STEM takes representation, seeing real examples. If I hadn’t known that being a scientist was a possibility as a young woman by seeing it with my own eyes, I might not have ended up in the field at all." – Jennifer Doudna
#WomenInScience
Photo:
@chrismichel
IGI founder Jennifer Doudna has won the 2020 Nobel Prize in Chemistry!
#CRISPR
genome editing has opened up new & wide-ranging possibilities across biology, agriculture & medicine — and there is so much more to come!
@UCBerkeley
@UCSF
@doudna_lab
In addition to her
#NobelPrize
-winning
#CRISPR
work, Jennifer & colleagues spun up a
#COVID19
testing lab at IGI in just three weeks!
Check out our blueprint for setting up a testing lab:
And learn more about our COVID research:
Big day at IGI! We received our first samples for
#COVID19
diagnostic testing, hand-delivered by Dori Tieu of the
@CityofBerkeley
Fire Department this morning.
We will test our firefighters continuously to make sure they stay healthy.
#igicoronatesting
IGI Founder Jennifer Doudna (
@doudna_lab
) speaking with
@POTUS
at a meeting last month in San Francisco to discuss AI risk mitigation! This is an official White House photo by Adam Schultz.
We're beyond excited to unveil our newly ILLUSTRATED glossary! The immensely talented
@christineliuart
made an awesome custom icon for every entry and we couldn't be happier. Check it out!
10 years ago today, the paper that showed how
#CRISPR
could be used as a genome-editing tool appeared in
@ScienceMagazine
, paving the way for rapid advances in medicine, agriculture & life science research. Read more on the backstory & progress:
"I imagine a day when we can prevent asthma. Imagine that we could manipulate the microbiome to eliminate disease-causing molecules that the microbiome emits that give some people susceptibility to asthma." — Jennifer Doudna on Marketplace.
"You go into the lab, do an experiment, and get a little bit of knowledge about the world that unravels another piece of the mystery of nature. I love that." -
#NobelPrize
winner Jennifer Doudna
We're thrilled to release our new collection of illustrations of SARS-CoV-2, the virus that causes
#COVID19
!
We're sharing these with a
@creativecommons
BY-NC-SA 4.0 license so you can use & adapt them for papers, talks, social media, homework, & more!
Happy birthday to Rosalind Franklin, co-discoverer of the structure of DNA! 🧬🎂
In 1952, Franklin produced an X-ray diffraction image of DNA known as ‘photo 51,’ which gave crucial evidence of DNA's double-helix shape.
#OTD
#WomenInSTEM
#RosalindFranklin
Role models are key to breaking barriers. If you're not aware of the late, openly trans neuroscientist & champion of
#InclusiveSTEM
Ben Barres, take a minute to hear him from him in his own words:
#Pride
#PrideMonth
#LGBTQinSTEM
Illustration by
@mpk_draws
Jennifer Doudna (
@doudna_lab
) and researchers at
@GladstoneInst
used
#CRISPR
to target and rapidly destroy brain cancer cells 🧠 in an approach that could potentially apply to other highly mutated cancers. Read more:
*Now accepting applications!*
@toryburch
and Jennifer Doudna have teamed up to offer the
@ToryBurchFdn
Fellowship at the IGI, supporting a woman entrepreneur in leading & scaling an early-stage business in genomics. Learn more & apply here:
#WomenInSTEM
Happy birthday to Rosalind Franklin, pioneering chemist & crystallographer, and co-discoverer of the structure of DNA!
Learn more about her remarkable contributions to science:
#OTD
#WomenInSTEM
#RosalindFranklin
2022 marks the first year
#CRISPR
-edited foods could be found on grocery shelves – and it's just the beginning! Learn about how CRISPR is being used in plant 🍅 & animal 🐮
#agriculture
in our year-in-review, written by IGI grad student
@Carrotvolias
:
Some things you do in life fill you with a deep pride. Our documentary
#HumanNatureFilm
is one of those. It's about
#CRISPR
, a science revolution that gives humans the potential to control our own evolution. Wow! Please check it out and share with others.
The CRISPR documentary
#HumanNatureFilm
—featuring several IGI leaders—is available on demand on Amazon, iTunes, Vimeo, and Google Play! From Executive Producer
@DanRather
and
@wondercollab
.
Preview and viewing links here:
Out now: our paper on CasPEDIA! CasPEDIA entries have comprehensive info on structure, function, and sequences, plus experimental considerations. Like Wikipedia, users can suggest new entries as new proteins are discovered and described. More here:
"Life-saving medicine cannot be treated as a luxury, and we cannot simply wait to let market forces drive prices down over time." — Jennifer Doudna (
@doudna_lab
) on affordability &
#CRISPR
medicines in
@WIRED
.
Read here:
"She could see things nobody else could see—and a lot of them just didn’t fit.” ➡️ IGI Microbiology Director
@BanfieldJill
revolutionized our understanding of the microbial world. Get a peek into the mind behind the science:
IGI is teaming up with
@DanaherCorp
to focus on creating treatments for two rare immune disorders! We hope to scale this work into a
#CRISPR
platform in which a new medicine for any genetic disease can be rapidly developed. Learn more:
#RareDisease
Darrion Nguyễn – "the Bill Nye of millennials" – is the science communicator and biochemist behind
@lab_shenanigan
, where he shares fun videos about science & lab life.
#Pride
#LGBTQinSTEM
People have been asking us how we set up the
#igicoronatesting
lab at
@UCBerkeley
.
We laid out a blueprint on
@medrxivpreprint
to help colleagues at other institutions establish their own
#COVID19
diagnostic testing centers. Please RT and share!
There's a new Cas protein in town! The archaeal protein Cas14 is ~1/3 the size of Cas9, targets ssDNA, and indiscriminately cuts nearby ssDNA like Cas12.
Fantastic collaborative work between
@doudna_lab
,
@BanfieldLab
, and
@LBNLBioSci
!
Twenty years ago today, IGI's
@BanfieldJill
published her seminal paper on genome-resolved
#metagenomics
, opening new frontiers in microbiology and ecology research!
Read the original
@Nature
paper here:
Photo credit
@jgi
Introducing CRISPR Made Simple – our new online primer on DNA, genes, and gene editing. Made for kids or anyone starting from scratch, and featuring illustrations by
@Miriampippaart
! Check it out:
#STEMEd
#SciComm
#SciArt
#CRISPR
On the 100th anniversary of her birth, we are celebrating Rosalind Franklin, pioneering chemist & crystallographer, and co-discoverer of the structure of DNA!
Learn more about her remarkable contributions to science:
#OTD
#WomenInSTEM
#RosalindFranklin
A phage army approaches and only Cris Perotein can defend the city of Bacterium from complete annihilation!
Watch Jennifer Doudna play "Phage Invaders: A CRISPR Game." Can you beat her score? 🎮
Watch the video:
Play the game:
ICYMI, join us in a 360° virtual field trip and learn about how to E.D.I.T. DNA with
#CRISPR
. We had a blast filming our tour of the IGI with
@__Ka1
and Jennifer Doudna!
Congratulations to Dave Savage (
@SavageCatsOnly
) on being named an HHMI Investigator! Dave aims to make crops more productive by increasing carbon capture with a little help from bacteria. Learn more here:
@HHMINEWS
New: The first clinical trial using CRISPR to directly correct the genetic defect that causes sickle cell disease is now getting underway, involving the IGI and a team of experts at three UC campuses:
@UCSFBenioffOAK
@UCLAstemcell
IGI Founder Jennifer Doudna in Vancouver yesterday telling the
@TEDTalks
audience about our 'audacious' new initiative in precision microbiome editing! 🧬 Learn more here:
@TheAudaciousPrj
#TED2023
#CRISPR
More photos + video of Jennifer getting the
@NobelPrize
medal will be streamed tomorrow morning as part of the official award ceremonies! Streaming starts at 7:30 am PT. Watch here:
Congratulations to our Executive Director, Jennifer Doudna (
@doudnalab
), on being awarded a 2020 Guggenheim Fellowship!
Our colleague Noah Whiteman (
@NKWhiteman
), another
@UCBerkeley
prof, is a 2020 awardee too—well-deserved! 🎉
Congratulations to my two colleagues, Professors Jennifer Doudna (
@berkeleyMCB
@igisci
) and Alison Gopnik (Psychology), the other
@Cal
@UCBerkeley
scholars awarded Guggenheim Fellowships this year!
How can institutions safely reopen during the
#COVID19
pandemic? IGI is launching the FAST study to address this question. In doing so, it will provide regular saliva testing to
@UCBerkeley
personnel working on campus. See for more info!
"The Little Enzyme That Can: Meet the Gene Editor CasX"
The new kid on the block is tiny but mighty. Evolved independently from other
#CRISPR
-Cas enzymes, this small scalpel packs a punch well above its weight.
#CasX
CRISPRpedia is IGI's new textbook-style resource on everything
#CRISPR
! Chapter 1 describes how CRISPR works in nature – Learn about the epic & never-ending battle between microbes & viruses! (And use our illustrations for free!)
#SciArt
#STEMed
Join Jennifer Doudna (
@doudna_lab
) and Siddhartha Mukherjee (
@DrSidMukherjee
) for an exciting conversation about
#GeneEditing
and the future of humanity. January 18th at Hertz Hall
@UCBerkeley
. Reserve your spot at this FREE event:
Thrilling news in tough times: A year and half after being the first person to receive a ground-breaking
#CRISPR
treatment for
#SickleCell
disease, Victoria Gray is thriving! Her journey, as reported by
@robsteinnews
@NPR
:
Missed Jennifer Doudna (
@doudna_lab
) and Siddhartha Mukherjee (
@DrSidMukherjee
) in conversation? Watch the full video here:
Who would you like to see on stage for a future discussion? Talking about what topic?
We're floored at the outpouring of support to help us establish clinical
#COVID19
testing at
@UCBerkeley
! We are no longer seeking volunteers.
If you filled out our form, we'll contact you if and when there's a role for you.
Thanks for your support! 🙏 💪
We are working as hard as possible to establish clinical
#COVID19
testing capability at
@UCBerkeley
campus.
We will update this page often to ask for reagents, equipment, and volunteers:
Please RT and share with Bay Area researchers!
Fantastic IGI project out in
@nature
today: "CRISPR-guided DNA polymerases enable diversification of all nucleotides in a tunable window." Dueber & Schaffer labs add directed evolution to the
#CRISPR
toolbox!
Paper:
Press release:
IGI &
@ucdavis
scientist Pam Ronald has won the World Agriculture Prize for her pioneering work, including finding genes in rice that have lead to the development of high-yield, flood-tolerant strains used by millions of farmers! 🧬 🌍 🍚 Congrats
@pcronald
! 🎉
Congratulations to
@navneetkmatharu
, Lin Du &
@JRo_Hamilton
– IGI's 2022 HS Chau Women in Enterprising Science Fellows! Each is receiving seed funding and mentorship to grow new ventures around promising genomic biotechnologies. Learn more:
For
#IndigenousPeoplesDay
2020, we're cracking open a copy of Native American DNA: Tribal Belonging and the False Promise of Genetic Science by
@KimTallBear
, Canada Research Chair in Peoples, Technoscience & Environment. Fascinating read!
#NativeInSTEM
"If you know you are on the right track, if you have this inner knowledge, then nobody can turn you off."
Happy birthday to Barbara McClintock! Her groundbreaking discovery of genetic transposition was met with silence & scorn — before she was ultimately awarded a Nobel.
#OTD
In work out today in
@NatureComms
, IGI members
@peaceoliverkun
&
@pcronald
used CRISPR-Cas9 tools to make rice enriched for beta-carotene, aka vitamin A precursor. Lack of vit A is a major cause of blindness & infection in developing countries.
THREAD⬇️
“CRISPR makes it possible to get to a genetic condition or change genes in an organism faster than if we were to wait for evolution to do it." Jennifer Doudna on the future on 10 years of
#CRISPR
in
@TIME
:
¡Atención! We are looking for a
@UCBerkeley
work-study student for Spanish-language translations of STEM content for the IGI, including news articles, video captions, social media, and more. Learn more and apply:
#SciComm
#LatinxInSTEM
What's the latest news on
#CRISPR
clinical trials? We've got you covered with a comprehensive (and readable!) 2024 overview. Read here & share:
Featuring insights from
@UrnovFyodor
and
@j_eyquem
!
IGI researchers Melanie Ott and Jennifer Doudna, along with
@UCBerkeley
researcher Daniel Fletcher, have outlined the technology for a rapid
#CRISPR
-based
#COVID19
test that uses a smartphone to get results in under 30 minutes! Learn more:
Crazy for CRISPR? Check out our IGI journal club designed for
@UCBerkeley
undergrads! Every Tuesday from 6–7pm, learn about the latest clinical trials, edited crops, and new CRISPR proteins. Email igi-events
@berkeley
.edu to RSVP!
We'll even serve you dinner! 🌮🥪🍕
Undergrads: Sign up for our summer CRISPR Course! Over 3 weeks you’ll hear about 12 CRISPR topics from leading scientists! Take what you learn in the classroom and edit DNA in the
@berkeleyMCB
lab 🔬
Register for MCB N184 on
@UCBerkeley
's course catalog: