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medRxiv

@medrxivpreprint

4 years

A serological assay to detect SARS-CoV-2 seroconversion in humans #medRxiv

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2 years

Saliva swabs are the preferred sample for Omicron detection #medRxiv

Saliva swabs are the preferred sample for Omicron detection

The Omicron variant is characterised by more than 50 distinct mutations, the majority of which are located in the spike protein. The implications of these mutations for disease transmission, tissue...

www.medrxiv.org

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3 years

Viral Load of SARS-CoV-2 in Respiratory Aerosols Emitted by COVID-19 Patients while Breathing, Talking, and Singing #medRxiv

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4 years

Aerosol and surface stability of HCoV-19 (SARS-CoV-2) compared to SARS-CoV-1 #medRxiv

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2 years

SARS-CoV-2 Omicron triggers cross-reactive neutralization and Fc effector functions in previously vaccinated, but not unvaccinated individuals #medRxiv

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4 years

Individual variation in susceptibility or exposure to SARS-CoV-2 lowers the herd immunity threshold #medRxiv

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4 years

Estimating the scale of COVID-19 Epidemic in the United States: Simulations Based on Air Traffic directly from Wuhan, China #medRxiv

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4 years

ACE2 variants underlie interindividual variability and susceptibility to COVID-19 in Italian population #medRxiv

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3 years

Vaccinated and unvaccinated individuals have similar viral loads in communities with a high prevalence of the SARS-CoV-2 delta variant #medRxiv

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2 years

Emergence and widespread circulation of a recombinant SARS-CoV-2 lineage in North America #medRxiv

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3 months

Underestimation of SARS-CoV-2 in wastewater due to single or double mutations in the N1 qPCR probe binding region #medRxiv

Underestimation of SARS-CoV-2 in wastewater due to single or double mutations in the N1 qPCR probe...

Wastewater surveillance using RT-qPCR has now been widely adopted to track circulating levels of SARS-CoV-2 virus in many sewer sheds. The CDC qPCR assays targeting two regions (N1 and N2) within the...

www.medrxiv.org

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4 years

Longitudinal evaluation and decline of antibody responses in SARS-CoV-2 infection #medRxiv

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4 years

Less severe course of COVID-19 is associated with elevated levels of antibodies against seasonal human coronaviruses OC43 and HKU1 (HCoV OC43, HCoV HKU1) #medRxiv

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2 years

SARS-CoV-2 testing of aircraft wastewater shows that mandatory tests and vaccination pass before boarding did not prevent massive importation of Omicron variant in Europe #medRxiv

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7 months

Suppressed IgG4 class switching in dupilumab- and TNF inhibitor-treated patients after repeated SARS-CoV-2 mRNA vaccination #medRxiv

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4 years

SARS-CoV-2 virus and antibodies in front-line Health Care Workers in an acute hospital in London: preliminary results from a longitudinal study #medRxiv

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3 years

Infectious SARS-CoV-2 in Exhaled Aerosols and Efficacy of Masks During Early Mild Infection #medRxiv

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medRxiv

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4 years

No evidence of clinical efficacy of hydroxychloroquine in patients hospitalized for COVID-19 infection with oxygen requirement: results of a study using routinely collected data to emulate a target trial #medRxiv

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2 years

A Bivalent Omicron-containing Booster Vaccine Against Covid-19 #medRxiv

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4 years

Performance Characteristics of the Abbott Architect SARS-CoV-2 IgG Assay and Seroprevalence Testing in Idaho #medRxiv

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1 year

The 2022 RSV surge was driven by multiple viral lineages #medRxiv

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medRxiv

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2 years

Covaxin (BBV152) Vaccine Neutralizes SARS-CoV-2 Delta and Omicron variants #medRxiv

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5 months

Whole-genome sequencing of half-a-million UK Biobank participants #medRxiv

Whole-genome sequencing of half-a-million UK Biobank participants

Whole-genome sequencing (WGS) provides a comprehensive view of the genome, enabling detection of coding and non-coding genetic variation, and surveying complex regions which are difficult to genoty...

www.medrxiv.org

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2 years

FinnGen: Unique genetic insights from combining isolated population and national health register data #medRxiv

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3 years

Risk of Myocarditis from COVID-19 Infection in People Under Age 20: A Population-Based Analysis #medRxiv

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3 years

Genetic associations of protein-coding variants in human disease #medRxiv

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3 years

Comparison of seven commercial SARS-CoV-2 rapid Point-of-Care Antigen tests #medRxiv

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medRxiv

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2 years

Increasing SARS-CoV2 cases, hospitalizations and deaths among the vaccinated elderly populations during the Omicron (B.1.1.529) variant surge in UK. #medRxiv

Increasing SARS-CoV2 cases, hospitalizations and deaths among the vaccinated elderly populations...

BACKGROUND There were increased SARS-CoV2 hospitalizations and deaths noted during Omicron (B.1.1.529) variant surge in UK despite decreased cases, and the reasons are unclear. METHODS In this...

www.medrxiv.org

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4 months

Long COVID Disability Burden in US Adults: YLDs and NIH Funding Relative to Other Conditions #medRxiv

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3 years

Genomic characterization and Epidemiology of an emerging SARS-CoV-2 variant in Delhi, India #medRxiv

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1 year

Antiviral innate immunity is diminished in the upper respiratory tract of severe COVID-19 patients #medRxiv

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4 years

Correlation between universal BCG vaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study #medRxiv

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@medrxivpreprint

4 years

Absence of SARS-CoV-2 neutralizing activity in pre-pandemic sera from individuals with recent seasonal coronavirus infection #medRxiv

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medRxiv

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2 years

Estimates of excess mortality for the five Nordic countries during the Covid-19 pandemic 2020-2021 #medRxiv

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2 years

SARS-CoV-2 vaccine and increased myocarditis mortality risk: A population based comparative study in Japan #medRxiv

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2 years

The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism #medRxiv

The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine...

Vaccination-based exposure to spike protein derived from early SARS-CoV-2 sequences is the key public health strategy against COVID-19. Successive waves of SARS-CoV-2 infections have been character...

www.medrxiv.org

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4 years

Strong Correlation Between Prevalence of Severe Vitamin D Deficiency and Population Mortality Rate from COVID-19 in Europe #medRxiv

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4 years

Reduced ICU demand with early CPAP and proning in COVID-19 at Bradford: a single centre cohort #medRxiv

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@medrxivpreprint

3 years

S-variant SARS-CoV-2 is associated with significantly higher viral loads in samples tested by ThermoFisher TaqPath RT-PCR #medRxiv

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3 years

Financial and Non-financial Conflicts of Interest Among the Japanese Government Advisory Board Members Concerning Coronavirus Disease 2019 #medRxiv

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3 years

Prevalence of vitamin D is not associated with the COVID-19 epidemic in Europe. A judicial update of the existing evidence. #medRxiv

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4 years

COVID-19 Antibody Seroprevalence in Santa Clara County, California #medRxiv

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2 years

Emergence in Southern France of a new SARS-CoV-2 variant of probably Cameroonian origin harbouring both substitutions N501Y and E484K in the spike protein #medRxiv

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2 years

Use of face masks did not impact COVID-19 incidence among 10-12-year-olds in Finland #medRxiv

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2 years

Increased risk of infection with SARS-CoV-2 Beta, Gamma, and Delta variant compared to Alpha variant in vaccinated individuals #medRxiv

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4 years

Correcting under-reported COVID-19 case numbers #medRxiv

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1 year

Prolonged T-cell activation and long COVID symptoms independently associate with severe disease at 3 months in a UK cohort of hospitalized COVID-19 patients #medRxiv

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medRxiv

@medrxivpreprint

1 year

Mitochondrial fatty acid synthesis is essential for coordinated energy transformation #medRxiv

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medRxiv

@medrxivpreprint

2 years

Waning of SARS-CoV-2 booster viral-load reduction effectiveness #medRxiv

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3 years

Infliximab is associated with attenuated immunogenicity to BNT162b2 and ChAdOx1 nCoV-19 SARS-CoV-2 vaccines #medRxiv

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@medrxivpreprint

2 years

Presence of SARS-CoV-2 in food surfaces and public space surfaces in 3 districts of Lima, Peru. #medRxiv

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2 years

Recurrent SARS-CoV-2 Mutations in Immunodeficient Patients #medRxiv

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3 years

Comprehensive genetic diagnosis of tandem repeat expansion disorders with programmable targeted nanopore sequencing #medRxiv

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medRxiv

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3 years

Whole genome sequencing identifies multiple loci for critical illness caused by COVID-19 #medRxiv

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4 years

ICON (Ivermectin in COvid Nineteen) study: Use of Ivermectin is Associated with Lower Mortality in Hospitalized Patients with COVID19 #medRxiv

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medRxiv

@medrxivpreprint

3 years

SARS-CoV-2 antibodies remain detectable 12 months after infection and antibody magnitude is associated with age and COVID-19 severity #medRxiv

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@medrxivpreprint

2 years

Screening for SARS-CoV-2 persistence in Long COVID patients using sniffer dogs and scents from axillary sweats samples #medRxiv

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medRxiv

@medrxivpreprint

4 years

The impact of host resistance on cumulative mortality and the threshold of herd immunity for SARS-CoV-2 #medRxiv

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medRxiv

@medrxivpreprint

4 years

Estimation of seroprevalence of novel coronavirus disease (COVID-19) using preserved serum at an outpatient setting in Kobe, Japan: A cross-sectional study. #medRxiv

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medRxiv

@medrxivpreprint

2 years

Post-COVID-19 syndrome: retinal microcirculation as a potential marker for chronic fatigue #medRxiv

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medRxiv

@medrxivpreprint

2 years

Rapid emergence of SARS-CoV-2 Omicron variant is associated with an infection advantage over Delta in vaccinated persons #medRxiv

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medRxiv

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4 years

The Infectious Nature of Patient-Generated SARS-CoV-2 Aerosol #medRxiv

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2 years

High-throughput Genetic Clustering of Type 2 Diabetes Loci Reveals Heterogeneous Mechanistic Pathways of Metabolic Disease #medRxiv

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@medrxivpreprint

1 year

Emergence and antibody evasion of BQ and BA.2.75 SARS-CoV-2 sublineages in the face of maturing antibody breadth at the population level #medRxiv

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medRxiv

@medrxivpreprint

3 years

Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization. #medRxiv

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medRxiv

@medrxivpreprint

3 years

Model-based evaluation of transmissibility and reinfection for the P.1 variant of the SARS-CoV-2 #medRxiv

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medRxiv

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3 years

Efficacy of Colchicine in Non-Hospitalized Patients with COVID-19 #medRxiv

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5 months

Polygenic prediction of human longevity on the supposition of pervasive pleiotropy #medRxiv

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4 years

Exome sequencing identifies rare coding variants in 10 genes which confer substantial risk for schizophrenia #medRxiv

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medRxiv

@medrxivpreprint

3 years

Delta variant and mRNA Covid-19 vaccines effectiveness: higher odds of vaccine infection breakthroughs #medRxiv

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medRxiv

@medrxivpreprint

3 years

Epidemiological dynamics of the incidence of COVID-19 in children and the relationship with the opening of schools in Catalonia (Spain) #medRxiv

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medRxiv

@medrxivpreprint

2 years

Omicron outbreak at a private gathering in the Faroe Islands, infecting 21 of 33 triple-vaccinated healthcare workers #medRxiv

Omicron outbreak at a private gathering in the Faroe Islands, infecting 21 of 33 triple-vaccinated...

There are concerns that the SARS-CoV-2 Omicron variant evades immune responses due to unusually high numbers of mutations on the spike protein. Here we report a super-spreading event of Omicron...

www.medrxiv.org

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3 years

The effectiveness of the first dose of BNT162 b 2 vaccine in reducing SARS-CoV-2 infection 13-24 days after immunization: real-world evidence #medRxiv

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medRxiv

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3 years

Large-scale study of antibody titer decay following BNT162b2 mRNA vaccine or SARS-CoV-2 infection #medRxiv

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medRxiv

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3 years

Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2 infection #medRxiv

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medRxiv

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4 years

DETECTION OF AUTOLOGOUS BLOOD DOPING #medRxiv

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3 years

Evidence of transmission from fully vaccinated individuals in a large outbreak of the SARS-CoV-2 Delta variant in Provincetown, Massachusetts #medRxiv

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3 years

A genome-wide association study for nonalcoholic fatty liver disease identifies novel genetic loci and trait-relevant candidate genes in the Million Veteran Program. #medRxiv

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medRxiv

@medrxivpreprint

3 years

Characterizing menstrual bleeding changes occurring after SARS-CoV-2 vaccination #medRxiv

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medRxiv

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3 years

ACTIVATE-2: A DOUBLE-BLIND RANDOMIZED TRIAL OF BCG VACCINATION AGAINST COVID19 IN INDIVIDUALS AT RISK #medRxiv

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medRxiv

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11 months

Rapid nanopore metagenomic sequencing and predictive susceptibility testing of positive blood cultures from intensive care patients with sepsis #medRxiv

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4 years

Novel coronavirus 2019-nCoV: early estimation of epidemiological parameters and epidemic predictions #medRxiv

Novel coronavirus 2019-nCoV: early estimation of epidemiological parameters and epidemic predictions

In December 2019, a novel coronavirus (2019-nCoV) is thought to have emerged into the human population in Wuhan, China. The number of identified cases in Wuhan has increased rapidly since, and cases...

www.medrxiv.org

4

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4 years

Detection of Air and Surface Contamination by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Hospital Rooms of Infected Patients #medRxiv

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1 year

The genetic and phenotypic correlates of neonatal Complement Component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders #medRxiv

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medRxiv

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3 years

Proxalutamide (GT0918) Reduces the Rate of Hospitalization in mild-to-moderate COVID-19 Female Patients: A Randomized Double-Blinded Placebo-Controlled Two-Arm Parallel Trial. #medRxiv

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medRxiv

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3 years

Sudden rise in COVID-19 case fatality among young and middle-aged adults in the south of Brazil after identification of the novel B.1.1.28.1 (P.1) SARS-CoV-2 strain: analysis of data from the state of Parana #medRxiv

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4 years

Confirmed central olfactory system lesions on brain MRI in COVID-19 patients with anosmia: a case-series #medRxiv

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2 years

A Multi-Center Randomized Comparison of High-Intensity Interval Training and Moderate-Intensity Exercise to Recover Walking Post-Stroke: Results of the HIT-Stroke Trial #medRxiv

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4 years

Benefits and Risks of Chloroquine and Hydroxychloroquine in The Treatment of Viral Diseases: A Meta-Analysis of Placebo Randomized Controlled Trials #medRxiv

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2 years

Multi-PGS enhances polygenic prediction: weighting 937 polygenic scores #medRxiv

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4 years

Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia #medRxiv

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@medrxivpreprint

2 years

Omicron infection enhances neutralizing immunity against the Delta variant #medRxiv

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medRxiv

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2 years

Effect of Vitamin D3 supplementation vs. dietary-hygienic measures on SARS-COV-2 infection rates in hospital workers with 25-hydroxyvitamin D3 [25(OH)D3] levels >20 ng/mL #medRxiv

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medRxiv

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4 years

Hydroxychloroquine and Azithromycin as a treatment of COVID-19: preliminary results of an open-label non-randomized clinical trial #medRxiv

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medRxiv

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2 years

SARS-CoV-2 infection in vaccinated individuals induces virus-specific nasal resident CD8 and CD4 T cells of broad specificity #medRxiv

SARS-CoV-2 infection in vaccinated individuals induces virus-specific nasal resident CD8 and CD4 T...

Rapid recognition of SARS-CoV-2-infected cells by T cells resident in the upper airway might provide an important layer of protection against COVID-19. Whether parenchymal SARS-CoV-2 vaccination or...

www.medrxiv.org

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3 years

Sars-Cov-2 antibody titer 3 months post-vaccination is affected by age, gender, smoking and vitamin D. #medRxiv

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4 years

Therapeutic efficacy of Honey and Nigella sativa against COVID-19: A multi-center randomized controlled clinical trial (HNS-COVID-PK) #medRxiv

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3 years

Safety and immunogenicity of INO-4800 DNA vaccine against SARS-CoV-2: a preliminary report of a randomized, blinded, placebo-controlled, Phase 2 clinical trial in adults at high risk of viral exposure #medRxiv

Safety and immunogenicity of INO-4800 DNA vaccine against SARS-CoV-2: a preliminary report of a...

Background Vaccines against SARS-CoV-2 are still urgently needed as only 5% of the global population has been vaccinated. Here we report the safety and immunogenicity of a DNA vaccine (INO-4800)...

www.medrxiv.org

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1 year

High number of SARS-CoV-2 persistent infections uncovered through genetic analysis of samples from a large community-based surveillance study #medRxiv

High number of SARS-CoV-2 persistent infections uncovered through genetic analysis of samples from...

Persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections may act as viral reservoirs that could seed future outbreaks [1][1]–[5][2], give rise to highly divergent lineages...

www.medrxiv.org

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4 years

GWAS of Depression Phenotypes in the Million Veteran Program and Meta-analysis in More than 1.2 Million Participants Yields 178 Independent Risk Loci #medRxiv

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