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eLife - the journal

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The funder-researcher collaboration and open-access journal for research in the life and biomedical sciences | @eLifeCommunity

Cambridge, UK
Joined September 2011
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@eLife
eLife - the journal
10 days
💭 Why do amnesia patients dream differently? How do elephants dodge cancer? What’s going on inside kombucha? We've published over 1,000 Insight articles since 2012. Take a look at some of our favourites from over the years! 🧵 1/13
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@eLife
eLife - the journal
2 years
Today, we’re introducing a new model that eliminates accept/reject decisions. By publishing every paper with eLife reviews as a Reviewed Preprint, we plan to restore autonomy to authors, ensuring that they will be judged by what, not where, they publish.
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@eLife
eLife - the journal
5 years
Reviewer 2 agreed that the ability to determine structures directly within the cellular environment would "transform structural cell biology" #fromthedecisionletter #ResearchAdvance
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@eLife
eLife - the journal
2 years
PhDs can be challenging and public discourse tends to focus on the negatives. To bring back some balance and positive momentum, this group of students sought to highlight the positive elements of the PhD experience. #AcademicChatter #PhDChat
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@eLife
eLife - the journal
2 years
This study investigated how cell shape and the motility of individual cells influence how macrophages scan for signs of infection.
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@eLife
eLife - the journal
2 years
This study investigated how cell shape and the motility of individual cells influence how macrophages scan for signs of infection.
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@eLife
eLife - the journal
11 months
Cells can pass proteins and RNA to each other through tubes that act as a channel between their membranes.
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@eLife
eLife - the journal
2 years
Cancer cells hide inside other cancer cells when the immune system attacks, letting the cell inside survive.
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@eLife
eLife - the journal
3 years
The spike protein of SARS-CoV-2 interacts with cholesterol and ACE2 to induce viral entry and pathological cell-cell fusion. Can cholesterol-lowering statins be used as a treatment for COVID-19?
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@eLife
eLife - the journal
5 years
Today we’re delighted to announce Michael Eisen as our new Editor-in-Chief. Welcome, @mbeisen !
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@eLife
eLife - the journal
5 years
ICYMI advanced microscopy with custom software called MaMuT tracked the development of a crustacean over several days of embryogenesis
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@eLife
eLife - the journal
1 year
Molecular simulations reveal how membrane pores are formed by gasdermin-D, a protein important in cell death in inflammation and infection.
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@eLife
eLife - the journal
1 year
Molecular simulations reveal how membrane pores are formed by gasdermin-D, a protein important in cell death in inflammation and infection.
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@eLife
eLife - the journal
3 years
The spike protein of SARS-CoV-2 interacts with cholesterol and ACE2 to induce viral entry and pathological cell-cell fusion
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@eLife
eLife - the journal
2 years
The spike protein of SARS-CoV-2 interacts with cholesterol and ACE2 to induce viral entry and pathological cell-cell fusion
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@eLife
eLife - the journal
1 year
Molecular simulations reveal how membrane pores are formed by gasdermin-D, a protein important in cell death in inflammation and infection.
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@eLife
eLife - the journal
2 years
The spike protein of SARS-CoV-2 interacts with cholesterol and ACE2 to induce viral entry and pathological cell-cell fusion
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@eLife
eLife - the journal
10 months
Cells can pass proteins and RNA to each other through tubes that act as a channel between their membranes.
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@eLife
eLife - the journal
11 months
Cells can pass proteins and RNA to each other through tubes that act as a channel between their membranes.
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@eLife
eLife - the journal
2 years
Cancer cells hide inside other cancer cells when the immune system attacks, letting the cell inside survive.
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@eLife
eLife - the journal
6 years
Reviewer 2 agreed that the ability to determine structures directly within the cellular environment "will transform structural cell biology" #ResearchAdvance
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@eLife
eLife - the journal
3 years
Find yourself jumping between two PDFs when reading a paper? With our side by side view, you can see the figures and contents next to the main text in your browser window. You can find the "side by side" button on the left side of your screen when viewing an article.
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@eLife
eLife - the journal
4 years
From today, code can be an integral part of a paper published in eLife. Announcing the Executable Research Article, a new open format for research papers where code can be run directly in the browser
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@eLife
eLife - the journal
3 years
We are pleased to announce the next advancement in our mission to transform science publishing. From today, we take the next steps towards exclusively reviewing preprints. Learn more about these changes in an Editorial from Editor-in-Chief Mike Eisen ▸
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@eLife
eLife - the journal
2 years
This study investigated how cell shape and the motility of individual cells influence how macrophages scan for signs of infection.
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@eLife
eLife - the journal
2 years
New technology measures the release of dopamine simultaneously from hundreds of release sites at the spatial resolution of a synapse.
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@eLife
eLife - the journal
4 years
Ten common statistical mistakes to watch out for when writing or reviewing a manuscript
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@eLife
eLife - the journal
1 year
Molecular simulations reveal how membrane pores are formed by gasdermin-D, a protein important in cell death in inflammation and infection.
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@eLife
eLife - the journal
4 years
Ten common statistical mistakes to watch out for when writing or reviewing a manuscript
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@eLife
eLife - the journal
3 years
The spike protein of SARS-CoV-2 interacts with cholesterol and ACE2 to induce viral entry and pathological cell-cell fusion
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@eLife
eLife - the journal
6 years
Multi-view light-sheet microscopy images embryogenesis of the crustacean Parhyale hawaiensis
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@eLife
eLife - the journal
6 years
First, it eats them from the inside; then, it turns them into zombies. 📽️ Watch how the fungus E. muscae gets fruit flies under its control
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@eLife
eLife - the journal
11 months
Parasites can use extracellular vesicles and cellular projections called cytonemes to communicate with one another.
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@eLife
eLife - the journal
3 years
Brainrender is an #OpenSource and user-friendly software for combining any type of anatomically registered data into custom interactive 3D renderings
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@eLife
eLife - the journal
3 years
Researchers have developed a new single-objective light-sheet microscope and demonstrate its unparalleled resolution on a range of biological phenomena that would usually be challenging or even impossible to image in this way
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@eLife
eLife - the journal
2 years
Researchers have developed a new single-objective light-sheet microscope and demonstrate its unparalleled resolution on a range of biological phenomena that would usually be challenging or even impossible to image in this way
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@eLife
eLife - the journal
1 year
Chronic Ca2+ imaging of cortical neurons with long-term expression of GCaMP-X.
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@eLife
eLife - the journal
3 years
Today we are pleased to announce a new policy that provides a fair and unobtrusive way for authors, editors and reviewers to retroactively change their name in papers published in eLife
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@eLife
eLife - the journal
5 years
ICYMI an atomic model for an intact bacterial ATP synthase shows how individual amino acids contribute to ATP synthesis
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@eLife
eLife - the journal
2 years
Ants swap spit to create a colony-wide metabolism, functioning almost like a single organism.
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@eLife
eLife - the journal
2 years
This study investigated how cell shape and the motility of individual cells influence how macrophages scan for signs of infection.
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@eLife
eLife - the journal
2 years
We’re trying something new! eLife authors can now freely speculate the meaning and implications of their data in our new section: 💡 Ideas and Speculation 💡 (1/3)
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@eLife
eLife - the journal
3 years
The spike protein of SARS-CoV-2 interacts with cholesterol and ACE2 to induce viral entry and pathological cell-cell fusion. Can cholesterol-lowering statins be used as a treatment for COVID-19?
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@eLife
eLife - the journal
4 months
These cells are passing proteins and RNA to each other through tubes that act as a channel between their membranes. #12DaysOfeLife
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@eLife
eLife - the journal
2 years
Baby marmosets start making faces in the womb, practising the face and mouth movements they’ll use to communicate with their family before they’re even born.
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@eLife
eLife - the journal
5 years
Atomic model for an intact bacterial ATP synthase shows how individual amino acids contribute to ATP synthesis
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@eLife
eLife - the journal
2 years
Brainrender is an #OpenSource and user-friendly software for combining any type of anatomically registered data into custom interactive 3D renderings
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@eLife
eLife - the journal
4 years
We believe that being first should never take priority over doing things right; we offer scoop protection meaning authors are not penalized because another group has recently published similar findings
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@eLife
eLife - the journal
4 years
The central region of the fruit fly brain has been fully mapped in 3D for the first time, including roughly 20 million connections between some 25,000 neurons
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@eLife
eLife - the journal
3 years
Nanoscape is an interactive open-world experience that lets you navigate 3D cellular landscapes like in a video game
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@eLife
eLife - the journal
5 years
Study of 33 three-generation families suggests that each person has, on average, around 70 "de novo" mutations that were not present in their parent’s genetic code
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@eLife
eLife - the journal
8 months
💡 From a statistical mistakes guide to how to write a lab handbook, this thread compiles some of our most useful guides and advice for academics. 1/n 🤫 P.S. We’re also building a new resource for neurodivergent scientists with your input. Take a look!
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@eLife
eLife - the journal
3 months
In cultured cells, mitochondria maintain temperatures of up to 15°C above their environment adjusting their heat production in the face of physiological stresses.
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@eLife
eLife - the journal
3 years
A new method allows researchers to analyse the dynamics of immunological synapses while avoiding the limitations of fluorescence microscopy. The approach combines deep learning algorithms and a 3D imaging technique called optical diffraction tomography
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@eLife
eLife - the journal
2 years
Cancer cells hide inside other cancer cells when the immune system attacks, letting the cell inside survive.
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@eLife
eLife - the journal
1 year
The centrosome decides which branch extending from the body of microglia will successfully engulf and clear away dead neurons.
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@eLife
eLife - the journal
3 years
R and Python are increasingly used in research. Now you can share your code interactively in your paper when you publish an Executable Research Article.
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@eLife
eLife - the journal
3 years
As announced late last year, beginning today eLife will only peer review articles posted on a preprint server. You can learn more about these changes in our latest Inside eLife article ⬇️ 1/3
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@eLife
eLife - the journal
2 years
Researchers investigate the driving forces in the leading edge of a migrating cell.
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@eLife
eLife - the journal
6 months
The Board of eLife has made the decision to replace our Editor-in-Chief. Read more in the full statement .
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eLife - the journal
4 months
For the first time, scientists analysed the connectome for part of the brain in the common octopus involved in long-term memory. Here, they use #ElectronMicroscopy to trace the length of an axon micron by micron.
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@eLife
eLife - the journal
3 years
Researchers have made an immunofluorescence image map of 456 human kinase proteins representing 85% of the human kinome
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@eLife
eLife - the journal
3 years
A new method allows researchers to analyse the dynamics of immunological synapses while avoiding the limitations of fluorescence microscopy. The approach combines deep learning algorithms and a 3D imaging technique called optical diffraction tomography
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@eLife
eLife - the journal
4 years
Writing or reviewing a manuscript? Watch out for these ten common statistical mistakes
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@eLife
eLife - the journal
6 years
ICYMI multi-view light-sheet microscopy revealed embryogenesis of the crustacean Parhyale hawaiensis
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@eLife
eLife - the journal
3 years
A structural model of the SARS-CoV-2 spike protein as the virus fuses with host human cells reveals an opportunity to disrupt dynamics and halt transmission
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@eLife
eLife - the journal
2 years
Super resolution microscopy reveals how B cells form the tight connections needed to trigger the creation of antibodies.
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@eLife
eLife - the journal
1 year
Chronic Ca2+ imaging of cortical neurons with long-term expression of GCaMP-X.
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@eLife
eLife - the journal
1 year
Enhanced single RNA imaging reveals dynamic gene expression in live animals.
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@eLife
eLife - the journal
4 years
Researchers track individual cells inside “organoids” to find out whether a tumour can really start from a single faulty cell
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@eLife
eLife - the journal
2 years
Cancer cells hide inside other cancer cells when the immune system attacks, letting the cell inside survive.
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@eLife
eLife - the journal
2 years
Researchers find a novel mechanism by which an animal cell can move through a 3D extracellular matrix.
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@eLife
eLife - the journal
3 years
A structural model of the SARS-CoV-2 spike protein as the virus fuses with host human cells reveals an opportunity to disrupt dynamics and halt transmission
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@eLife
eLife - the journal
2 years
Part of the nuclear pore protein Nup358 forms a helix which is required for activation of a dynein-dependent transport pathway that is essential for brain development.
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@eLife
eLife - the journal
5 years
From Arabidopsis to zebrafish, these 12 essays explore what is known about the natural history of a range of model organisms and their wild relatives
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@eLife
eLife - the journal
3 years
The central region of the fruit fly brain has been fully mapped in 3D for the first time, including roughly 20 million connections between some 25,000 neurons
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@eLife
eLife - the journal
1 year
Chronic Ca2+ imaging of cortical neurons with long-term expression of GCaMP-X.
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@eLife
eLife - the journal
3 years
Scientists have developed a technology called G-baToN where cells exchange fluorescent proteins like the baton in a relay race, allowing the physical interactions of cells to be tracked
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@eLife
eLife - the journal
6 years
Photokinetic bacteria can be arranged into complex and reconfigurable patterns, including portraits, using a digital light projector
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@eLife
eLife - the journal
9 months
A lab handbook can help with the day-to-day challenges of running a lab and promote a positive culture. Here are in-depth resources, including a template, to help you write your own:
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@eLife
eLife - the journal
2 years
The 3D structure of kinetochore-fibres in human mitotic spindles.
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@eLife
eLife - the journal
3 years
The nucleus acts as a pacemaker for the mitotic cell cycle. Follow up question: what is the advantage for a cell to have the nucleus initiate mitosis?
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@eLife
eLife - the journal
11 months
pYtags enable spatiotemporal measurements of receptor tyrosine kinase signaling in living cells.
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@eLife
eLife - the journal
2 years
This study investigated how cell shape and the motility of individual cells influence how macrophages scan for signs of infection.
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@eLife
eLife - the journal
4 years
A new computational microscopy technique could make it easier to study live cells and human tissues without using fluorescent labels
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@eLife
eLife - the journal
1 year
Enhanced single RNA imaging reveals dynamic gene expression in live animals.
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@eLife
eLife - the journal
1 year
With three simple steps and in just 48 hr, EZ Clear effectively renders adult mouse organs optically transparent while preserving signals from fluorescent reporters.
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@eLife
eLife - the journal
3 years
Happy #FluorescenceFriday ! 🔬 We’re taking a break from regular posting to look back at some of the most spectacular fluorescence images and videos published in eLife. Got some of your own? Share them below ⬇️
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@eLife
eLife - the journal
4 years
Beginning today, we are pleased to invite authors who share their work as a preprint on bioRxiv to submit to our new @PreprintReview service
@PreprintReview
Preprint Review
4 years
Preprint Review offers authors the opportunity to have @eLife review their work directly on bioRxiv, and, simultaneously, consider the work for publication in the journal
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@eLife
eLife - the journal
4 years
Writing or reviewing a manuscript? Watch out for these ten common statistical mistakes
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eLife - the journal
1 year
The nuclear membrane protein SUN1 stabilises endothelial cell junctions by regulating microtubule dynamics to regulate blood vessel formation.
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eLife - the journal
5 years
Human stem cells respond differently to new signals depending on which messages they'd received in the past
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@eLife
eLife - the journal
3 years
The neural crest is a structure that gives rise to the brain, central nervous system and parts of the face. CRISPR-Cas9 has been used to find a mechanism involved in its creation
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@eLife
eLife - the journal
3 years
High-resolution imaging of zebrafish shows that the release of cellular components by pioneer neutrophils is an initial step in neutrophil swarming at sites of tissue injury
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@eLife
eLife - the journal
5 years
"First, it eats them from the inside; then, it turns them into zombies." 🧟 📽️ Watch how this fungus takes control of its fruit fly hosts
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@eLife
eLife - the journal
2 years
In this Insight Article, Sebastian describes how implementing robotics and artificial intelligence is optimising cell culture protocols to reliably produce cell types useful to regenerative medicine.
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@eLife
eLife - the journal
4 years
"This study reveals the importance of scientists considering that genes that affect behaviour may do so by changing anatomy rather than by altering the brain"
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@eLife
eLife - the journal
1 year
EZ Clear is a new tissue clearing procedure that’s faster, uses less hazardous chemicals, and appears to result in less tissue volume change.
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@eLife
eLife - the journal
4 months
Data from 56 different species sheds light on the diversity and evolution of cerebellar folding in mammals.
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@eLife
eLife - the journal
7 months
Epithelial cells actively respond to mechanical signals from neighbouring cells through active coupling and mechano-structural polarisation.
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