Physician scientist, cardiologist
@Yale
, working on translational research in cardio-onc, imaging, genomics & CV effects and mechanisms of somatic variants/CHIP
@Olympics
🥇medalist
@nathanwchen
explores a day in the life of physician scientists, highlighting the importance of supporting their work to improve human health. Glad to hear of his interest in this career. Congrats on winning an
@AHAScience
award!
#Genomics
QC🧬🫀 health
#linux
What's Olympian gold🥇medalist
@nathanwchen
's next move? Look forward➡️working w/him to communicate the importance of biomedical research🧬🧪to improve human health & hear about his career goals in Medicine🩺💊🏥!
@janiceschen
#Nathanchen
#jurrassicparksci
Thanks Aneesh.agrawal,
@justin_spired
et al for hosting us
@instagram
, w/>2 billion person reach, glad to hear of efforts to tackle misinformation! Addressing science & medical misinformation is crucial for well being of society!
@peterhotez
@EricTopol
;
@nathanwchen
mtg w/fans!
So inspiring to meet
@SammyBasso
&
@Progeria
research team including Dr Leslie Gordon & Dr Collins
@NIH
to see the potential of
#geneediting
to improve the plight of progeria patients & beyond. Exciting work toward clinical trials! Thx for having us in the discussion
@davidrliu
!
Be inspired in 15 minutes:
@SammyBasso
, the world's oldest living progeria patient, explains how he maintains such a positive life philosophy, working with us every week to advance a gene editing treatment towards the clinic.
Video:
@BrilliantMindsSthlm
.
@teamusa
@USFigureSkating
has won figure skating gold nearly two years after the Beijing Olympics due to a doping scandal that disqualified a Russian skater.
The team adds that they "would love" to have an official medal ceremony at the Paris Olympics!
Happy to host Yale undergraduate science major (and reigning Olympic figure skating champion / 3x world champion)
@nathanwchen
& Professor
@jennkwanMDPhD
in our lab for a week of experiments, data analysis, and outreach activities. Thank you
@IPWitte
for showing Nathan the ropes.
Great to catch up with friends
@illumina
and always inspiring to review the innovation wall of patents! Thx Jason for the mtg & tour!
@nathanwchen
@KnowingAlok
Thanks
@GrailBio
leadership for reviewing your pioneering
#galleri
test that can detect up to 50 cancers early, impressed w/low false (+) rate/high PPV compared to traditional cancer screening; look forward to seeing your clinical trial results!
@JeffreyVenstrom
@tinaclarkedur
Applying for a
@NIH
K award? Want guidance/tips from a leader in career development who has been invited to give grant writing workshops around the country? Join us for
@A_P_S_A
's K grant writing session on Sat 7/25/20, 1pm-230pm EST
#physicianscientist
@JAMA_current
study of 39k+ investigators in clinical depts
#physicianscientists
, over 10 yr period shows that
@NIH
research funding gaps are the norm, not the exception, w/average gaps of 2-3 yrs ➡️Implications for tenure/need for bridging
At Panasonic, the well-being of our planet is our top priority. As we officially kick off our
#GREENIMPACT
initiative alongside
@naomiosaka
,
@nathanwchen
, and
@m_phelps00
, we’re striving for a greener, healthier, more equitable future. More at
#CES2023
.
Skip brass
@PennMedicine
getting
@A_P_S_A
founders award: data on funding $ sources of physician scientists who stayed in research careers, majority had non
@NIH
funding ➡️ lessons learned
Interested in unraveling the role of somatic variants/CHIP in cardiovascular disease 🫀/aging using genomics🧬/imaging?
The Kwan lab, co-mentored with Dr Alok Jha has an opening for a postdoctoral fellow:
Info and how to apply:
#bigdata
#genomics
#AI
#ML
In
@AcadMedJournal
today: Assessing impact of
#COVID19
on phy scientist trainees👩⚕️to faculty🩺during the initial peak of the pandemic showed ⬆️high stress, impaired productivity. F/u survey 1.5 yrs out shows both stress & impaired productivity🚫improved.
Majority of $ for
#physicianscientists
in academia come from non
@NIH
funds per
@AAMCtoday
MD PhD program outcomes study; hear about opportunities & approaches to obtaining non NIH funding (as we advocate to⬆️
@NIH
$). Join us on June 9, 2-3pm EST
Cardiomyocytes release subcellular particles called exophers that transport defective mitochondria for elimination by macrophages
🤯
Cardiac muscle cells outsource mitophagy to neighboring macrophages. Division of labor. Efficiency.
@AndrsHidalgo16
As
@A_P_S_A
policy chair, we invited
#RBG
to discuss the importance of policy, gender equality in science/medicine; although her schedule did not permit, her work continues to inspire us to advocate for a more just society. We thank her for her efforts in life & on the court!
Ben Ebert
@DanaFarber
reviews CHIP, a proinflammatory state⬆️🫀disease risk. CHIP⬆️w/age; sequencing technique🔼prevalence. DNMT3a=♀️ biased, other CHIP mutations=♂️ biased. Chemo⬆️CHIP risk
#CardioOnc
What about CHIP in
#cardioonc
patients? Join me @
@ACCinTouch
22
#Baseediting
advances in treating disease w/
@davidrliu
, single shot💉w/potential➡️⬇️CV risk for a lifetime w/
@skathire
,
#geneediting
for diagnostics/therapeutics w/
@janiceschen
& insights from a US defense/security expert for potential areas of misuse/bioterror; must-see session!
What does the management of immunosuppression resistant
#ICImyocarditis
look like? One of the rising
@YaleIMed
@YaleMed
chief IM residents, Ritu Jayakrishnan, will take us through their courses; outcomes are in the works.
APSA's advocating for ⬆️$ funding support for early career
#physicianscientists
. This biomedical workforce = crucial for disease cures/preventions. Join us! Submit a video: show why your research/supporting early career physician-scientists is important
@NEJM
@HarvardChanSPH
"The intense scientific communication . . . combined with scientific advances, has enabled research to move faster than during any previous outbreak. “An unprecedented amount of knowledge has been generated in 6 weeks."
#COVID2019
@ScienceMagazine
Our
@JAMA_current
commentary w/
@cpgYALE
: We discuss ways to address $ gaps to retain phy-sci to move forward disease understanding & improve health. ie⬆️
@NIH
funding to keep up w/inflation, include $ for research for health-related legislation ie PCORI etc
@repmarkpocan
:If you had $10, 20, 70 billion more, what would that mean as far as research?
@NIHDirector
: We could provide for this amazing research workforce . . . I would focus on early stage investigators . . . they're our future . . .
@PeterHotez
@NIH
An inspirational scientist, mentor & role model using her platform to advocate for positive change & using her expertise to tackle
#COVID19
@VirusesImmunity
Excited to have
@hmkyale
as my faculty mentor for
@YaleCardiology
journal club tomorrow to discuss ways to assess the quality/validity of observational
#bigdata
studies, lessons/insights from the recent
@TheLancet
&
@NEJM
Surgisphere papers
My comment about Surgisphere articles: '“Well-done studies are based on understanding the provenance of data & making sure what you are doing is reasonable."
@davidrliu
discusses
#baseediting
journey➡️therapeutics,
@skathire
highlights 15 yrs of research ➡️translation single 💉to ⬇️CV risk,
@janiceschen
shows roadmap of how
#geneediting
tech can help w/prevention ➡️💊➡️health, Lt colonel McGovern highlights potential misuse
National study of MD-PhD & MD trainees to assess career sector/specialty/research intentions identifies important factors driving career decisions & obstacles facing this cohort; MD RI =research intense
@A_P_S_A
@DaniaDaye
@otoubat
@drbrowncares
Co-infection rates of
#COVID19
w/other resp viruses: specimens + for SARS-CoV-2, 20.7% were + for 1 or more pathogens: ie rhinovirus (6.9%), RSV (5.2%). Presence of non–SARSCoV2 virus does not mean that a pt doesn't ALSO have SARS-CoV-2
@Stanford
Retrospective study of
#breastcancer
pts: we evaluated effects of anthracycline/Her2i (AT) vs those w/o on
#CMR
imaging characteristics & outcomes. AT w/⬆️biV volumes,⬇️RVEF. Most w/abnormal strain; anthracycline grp:⬆️abnormal GLS compared to those w/o
Yes, we're seeing this disparity for early career👩🔬 physician scientists, particularly if they have children🤱from our
@A_P_S_A
#COVID19
survey. Goal: assess impact of
#COVID19
on MD/PhD trainees to residents/fellows/junior faculty in terms of training/career/wellness
#advocacy