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@PacBio

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Our mission is to enable the promise of #genomics to better human health by creating the world’s most advanced #sequencing technologies. #PacBio

Menlo Park, California
Joined May 2009
Don't wanna be here? Send us removal request.
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@PacBio
PacBio
1 month
A lot has changed in the world of long-read sequencing. Can you spot the myths from the facts? ​ • HiFi error rate: 0.1% or 10%? ​ • Seq cost per Revio SMRT Cell: ~$1,995 or ~$995?​ • Output per Revio run: 24 or 360 Gb?​ See how you did: #HiFiFacts
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@PacBio
PacBio
7 months
RNA is an essential biomolecule that helps make us who we are. Which #RNA type matches your personality best? Share your pick in the comments, tag a friend, and follow PacBio for a chance to win a fun prize! T&Cs apply: #ASHG23 #PacBio
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@PacBio
PacBio
10 months
#PacBio is ready to turn up the music! 🎵 Help us create the soundtrack of the summer for a chance to win a prize. 😎 T&Cs apply: 1. Comment with your song choice 2. Tag a friend 3. Follow PacBio
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@PacBio
PacBio
1 year
We're celebrating #DNADay23 early with a fun giveaway! The first word you see in the word search puzzle is your science superpower! Leave a comment with the first word you see & tag a friend for a chance to win a prize! T&Cs apply:
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@PacBio
PacBio
3 years
Luckily, you don't have to wait long for results on the new Sequel IIe System...
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@PacBio
PacBio
4 years
Join our educational webinar to learn the basics of DNA Sequencing! Find out why long reads are beneficial & get your questions answered by our panel of sequencing gurus: @lissagoingviral @OlgaVPettersson & Michael Hardigan @UCDavisPlants Register:
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@PacBio
PacBio
3 months
#AGBT24 , you brought the cool factor to the #PacBio HiFi Lounge last night. 💯 It was great to see so many friendly and new faces! The fun continues tonight and tomorrow night, including announcing our giveaway winners to the concert of your choice!🥳 #AGBT
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@PacBio
PacBio
3 years
DNA Extraction Tip 3: When sequencing plants, it is recommended to obtain the youngest leaf/shoot tissue from an individual plant that has been dark treated (kept out of light) for 24-72 hours. #Sequencing101 More at:
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@PacBio
PacBio
4 years
What exactly is "SMRT Sequencing"? What are "long reads," for that matter? Confused about some of the basics of DNA sequencing, but too afraid to ask? Fear not, friends. We're offering a free Sequencing 101 webinar to break it down for you. Feb 27.
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@PacBio
PacBio
5 years
It's here! We’re thrilled to announce the launch of the Sequel II System, reducing project costs & timelines with approximately eight times the data output compared to the previous Sequel System. Look at that beauty! 1/3
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@PacBio
PacBio
2 years
We’ve partnered with the @broadinstitute and @10xgenomics to launch the Multiplexed Arrays Sequencing (MAS-Seq) kit, an accurate and cost-effective long-read single cell #RNASeq solution. Learn more here: #PacBio #ASHG22
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@PacBio
PacBio
3 years
We are thrilled to announce a new collaboration with medical genetics leader @Invitae to develop an ultra-high-throughput clinical whole genome #sequencing platform. See the details:
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@PacBio
PacBio
7 months
🎉 Celebrating 1 Year of Revio! 🧬 We are blown away by the exceptional high throughput and outstanding accuracy of the #Revio data achieved by our #PacBio customers. Here's to many more years of game-changing discoveries! #ASHG23 #ASHG2023 #RevioAnniversary
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@PacBio
PacBio
1 year
We’re spreading the long-read love all this month by giving away free #Revio building block kits. Simply RT this post, follow @pacbio , and tag 2 friends for a chance to win! T&Cs apply: #AGBT23 #PacBio
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@PacBio
PacBio
1 year
Revio is officially on the way! First commercial shipments are en route to customers worldwide. Join us as we share glimpses into the excitement that's brewing - we can't wait to see what game-changing discoveries are on the horizon! #Revio #PacBio
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@PacBio
PacBio
10 months
G’day Melbourne! Excited for #icg2023 this week? Keep an eye out for #PacBio trams and billboards scattered throughout the city. Snap a pic & tag us for a chance to win exclusive limited edition swag. Drop by Booth 79-81 for more info!
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@PacBio
PacBio
2 years
Meet Revio and Onso- PacBio’s newest long-read and short-read sequencing systems. Differentiated technology with unparalleled accuracy. Your moment of discovery is waiting. Are you ready? #PacBio #ASHG22
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@PacBio
PacBio
4 years
Felicidades, @guarnitron & co of the @CrawLab at @Uniandes ! You've been crowned winner of the 2020 Plant & Animal #SMRTGrant ! You clearly had many fans (6.264 votes, to be exact) & we truly hope your project will help #SaveTheToads .
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@PacBio
PacBio
3 years
"We have entered a new era of insect genome biology." New preprint from @MtnScience @paulbfrandsen @joannalkelley @John_S_Sproul @AmLarracuente et al examines how long-reads are revolutionizing #entomology & where gaps still remain.
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@PacBio
PacBio
1 year
From shipping container to lab floor, the Broad Institute welcomes its first early-access Revio.
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@PacBio
PacBio
4 years
Checkmate, Chromosome 8: The First End-to-End Sequence of a Human Autosome. Congrats to @glennis_logsdon & the #T2T team on this amazing work! #HiFiReads
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@PacBio
PacBio
2 years
What an epic way to usher in a new era of #sequencing and the announcement of our two new systems, Revio and Onso, with an amazing performance by Maroon 5! #PacBio #ASHG22
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@PacBio
PacBio
4 years
Another novel way to explain the semantic dependence between the negation of exons, via @hagentilgner in our #ASHG20 #PBWebinar
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@PacBio
PacBio
2 years
Are you ready?
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@PacBio
PacBio
3 years
Super news from @sangerinstitute ! The UK hub of the @darwintreelife & other human & pathogen genetics projects has purchased 7 new Sequel IIe Systems, to add to their 5 current Sequels. They plan to sequence ~2,000 plant & animal genomes in the next 2yrs!
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@PacBio
PacBio
4 years
NEWS FLASH: The kit you've been eagerly awaiting is now available! The SMRTbell gDNA Sample Amplification Kit enables whole genome amplification starting from as little as 5 ng of genomic DNA. Find out more about it & our ultra-low DNA input workflow
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@PacBio
PacBio
3 years
Back to School! Have you checked out our #Sequencing101 series? Whether you're a novice or a pro, you're bound to learn something new! Evolution of DNA Sequencing: Sequencing steps: Understanding accuracy:
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@PacBio
PacBio
3 years
BREAKING: @ChildrensMercy invests in 4 additional Sequel IIe Systems, enabling the top pediatric center to scale up its innovative whole genome research into #rarediseases . Its 6 Sequels will be installed in the new nine-story @ResearchCM building. .
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@PacBio
PacBio
1 year
Another #Revio celebration! 🎉 We are thrilled that Macrogen installed the first Revio system in Asia. 🌏
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@PacBio
PacBio
1 year
Exciting news! DNA Link just stepped up their genomics game by purchasing multiple #Revio units, allowing them to deliver even higher quality data and services to their customers. 👏
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@PacBio
PacBio
3 years
"We have entered a new era of insect genome biology." New preprint from @MtnScience @paulbfrandsen @joannalkelley @John_S_Sproul @AmLarracuente et al examines how long-reads are revolutionizing #entomology & where gaps still remain.
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@PacBio
PacBio
3 years
IT’S OFFICIAL: PacBio Closes Acquisition of Omniome Today marks the beginning of a new era! Long-read and short-read #sequencing platforms together under one roof. The next step in enabling the promise of genomics to better human health 🧬 Learn more:
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@PacBio
PacBio
6 years
Announcing Sequel System 6.0 - what will you do with highly accurate single-molecule long reads? #PoweredbyPacBio
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@PacBio
PacBio
3 years
🦇 Happy #BatAppreciationDay ! 🦇 These little balls of fluff are called Honduran bats, also known as Caribbean white tent-making bats, native to the rainforests of Costa Rica. H/T @IFLScience & Milan Zygmunt
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@PacBio
PacBio
3 years
BREAKING: PacBio Signs Definitive Agreement to Acquire Omniome! Our combined forces will challenge the status quo of conventional NGS. How? Click here to learn more
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@PacBio
PacBio
11 months
We are excited to partner with @GeneticNijmegen on #raredisease research. Using #Revio , we may be able to identify key variants at scale with extraordinary accuracy and make a real difference in providing rare disease answers.
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@PacBio
PacBio
3 years
Cos we all ❤️ memes, right? Right?? #bandwagon #scienceiscool
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@PacBio
PacBio
2 years
Incredible experience at the #PacBio celebration tonight! The lights, the music, and the coming together of the #ASHG22 community, is there anything better?
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@PacBio
PacBio
5 years
A gift for entomologists & geneticists alike! New low-input protocol makes it possible to create high-quality genomes from a single insect. See what @drsarahdoom & @sangerinstitute achieved together in this @biorxiv preprint:
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@PacBio
PacBio
3 years
"We have entered a new era of insect genome biology." New preprint from @MtnScience @paulbfrandsen @joannalkelley @John_S_Sproul @AmLarracuente et al examines how long-reads are revolutionizing #entomology & where gaps still remain.
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@PacBio
PacBio
4 years
Want to learn about long-read sequencing? Attend our webinar on Feb. 27 to get an intro to our technology & its applications, followed by a panel discussion among experienced users: @lissagoingviral , @OlgaVPettersson , & Michael Hardigan from @UCDavisPlants
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@PacBio
PacBio
3 years
The largest genome (5 Gb) broke almost every tool commonly used in assembly processes, but they did it... AND created some cool new tools & super science along the way. Huge congrats to the @genomeark team on their #VGPFlagship release & @nature special!
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@PacBio
PacBio
7 months
🧵Check out these #PacBio poster presentations happening this afternoon at #ASHG23 :
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@PacBio
PacBio
7 years
Celebrating #WomenScienceDay at #AGBT17 ! 3 cheers for ladies in the lab We support #WomeninScience
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@PacBio
PacBio
3 months
Today, we announce two new high throughput library preparation kits and workflows that will offer never-before-achieved scale for #Revio . Learn more about these automated, scalable, and high-performance library preparation solutions: #PacBio #AGBT #AGBT24
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@PacBio
PacBio
5 months
NEW: The power of #PacBio #HiFisequencing shines in this @nature article highlighting the TRGT method, enabling unprecedented detection and comprehensive discovery of repeat expansions linked to dozens of monogenic diseases and #cancer .
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@PacBio
PacBio
3 years
A new high-quality bonobo genome assembly from @UW pinpoints specific variants that distinguish chimpanzee & bonobo lineages via @nature :
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@PacBio
PacBio
3 years
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@PacBio
PacBio
3 years
Highly accurate, no gaps, no mis-joins — just chromosome 8 in all its glory. The completion of the first-ever fully sequenced human autosome is a remarkable feat and we are honored that PacBio #HiFiReads played a pivotal role in helping to achieve it!
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@PacBio
PacBio
2 years
Today we announced that our new HiFiViral SARS-CoV-2 solution has successfully sequenced & captured the entire genome of the #Omicron variant lineage. Read our press release, including results from @inqababiotec , to learn more:
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@PacBio
PacBio
3 years
Happy #DNADay2021 ! Want to learn a bit more about DNA sequencing? We've got the series for you: Evolution of tech: Sequencing steps: Ploidy, haplotypes & phasing: #Sequencing101
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@PacBio
PacBio
3 years
News about a new 'complete' human genome was v exciting. What does it mean & how did #HiFiReads help the #T2T team fill in the final 8% gap? We dive in on our blog: Insider insight from @ArangRhie #SMRTLeiden talk also available:
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@PacBio
PacBio
10 months
The first #Onso short-read sequencing system has left the building! Featuring exceptional SBB chemistry, it unlocks the promise of groundbreaking discovery in #oncology , disease research, and beyond. Stay tuned to see what Q40+ accuracy can do. #PacBio
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@PacBio
PacBio
4 years
“We are now embarking on an era where all genetic variation in an individual will be completely discovered. Hundreds, and ultimately thousands, of new human reference genomes will be produced.” @glennis_logsdon @mrvollger & Evan Eichler in @nresearchnews
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@PacBio
PacBio
4 years
#DYK : >50% of #epilepsy can be traced to a genetic cause? When a child presents w/ seizures, genetic testing can help identify >100 underlying, often rare conditions. Which is why we're happy to partner with @Invitae to help shorten diagnostic odysseys.
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@PacBio
PacBio
3 years
When preparing samples for HiFi sequencing, you not only want DNA free from nicks and degradation, but you also want long fragments (tens of kilobases) to achieve those coveted long reads. Get some top DNA extraction tips on our latest #Sequencing101 post.
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@PacBio
PacBio
2 years
The Consortium for Long Read Sequencing (CoLoRS) is an international collaboration focused on creating a database of frequency information for human variation identified using long-read human whole-genome sequencing. #PacBio
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@PacBio
PacBio
4 years
Tracking the SWEET tooth of TALEs: @AdamBogdanove of the @BogLabCU has used SMRT Sequencing to uncover host resistance to rice and cotton pathogens. Learn more about his work with TAL effector genes &the creation of a 'TALome'
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@PacBio
PacBio
5 years
Researchers have sequenced all the centromeres in a multicellular organism showing that telomere-to-telomere assemblies are now possible! Congrats to @AmLarracuente & her colleagues @UofR who used SMRT Sequencing for the study published in @PLOSBiology
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@PacBio
PacBio
5 years
Help poor @seemaychou get her mom - and half the @UCSFMedicine community? - off her back. Her lab would love to have the Pacific Tick genome sequenced. Agree? Vote here: #pacificusdreams @ucsf_biochem @czbiohub
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@PacBio
PacBio
3 years
NEWSFLASH: Today we're launching new HiFi Sequencing workflow & software updates for the Sequel II + Sequel IIe Systems. 👍 New primers, clean up & binding kits 🙌 New library prep protocol w/ 3x reduction in DNA input 💪 SMRTLink boost
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@PacBio
PacBio
9 years
Meet the Sequel System: SMRT Sequencing w/higher throughput (~7x more reads), lower project costs & reduced footprint http://t.co/o86MOltMgs
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@PacBio
PacBio
7 months
Incredible experience at the #PacBio party tonight! The positive energy and the coming together to celebrate the #ASHG23 community are always one of our favorite parts. #ASHG2023
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@PacBio
PacBio
2 years
Welcome to the new #PacBio . Our mission is to enable the promise of #genomics to better human health. Learn more here:
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@PacBio
PacBio
2 years
Given the state of the pandemic & for the safety of our attendees, staff, colleagues, clients & their communities, we will no longer be hosting/ livestreaming our in-person workshop at #PAGXXIX . We look forward to hosting our workshop in a safer environment virtually soon.
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@PacBio
PacBio
6 years
Two genomes from one cross-bred cattle, distinguishing maternal & paternal haplotypes? It's possible, thanks to a trio-binning method from @aphillippy @sergekoren @ArangRhie @tplsmith . Popular at #PAGXXVI , now in preprint & on our blog:
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@PacBio
PacBio
5 years
Accurate circular consensus long-read sequencing improves variant detection and assembly of a human genome via @NatureBiotech . De novo genome assembly produced a contiguous and accurate genome with a contig N50 of >15 Mb & concordance of 99.997% #HiFiReads
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@PacBio
PacBio
5 years
Interested in winning free PacBio sequencing to explore your favorite plant or animal genome? Submit a 90 second video explaining how a high-quality genome will advance your science. Apply for a #SMRT Grant by Feb. 22:
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@PacBio
PacBio
2 years
We are proud to announce our new European headquarters in London to serve our growing customer demand, as well as the addition of Genesupport as our first commercial service provider in Europe. Learn more here: #PacBio
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@PacBio
PacBio
4 years
Live now - keynote talks from #SMRTLeiden online! We're thrilled to share 20+ speakers from around the world presenting their research powered by SMRT Sequencing. Watch: @LUMC_Leiden @erichjarvis @hagentilgner @anaconesa @sergekoren @NEBiolabs @corteva
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@PacBio
PacBio
6 years
This cheeky parrot is one of only 148 left in the wild & one of the first 15 genomes to be released by the @GenomeArk . Learn more about the #VGP project & the bird @takapodigs @Spokesbird #forJane @erichjarvis
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@PacBio
PacBio
3 months
Nanopore was worth a shot, right? But now you're ready for true high-accuracy long-read sequencing without compromise, and we're here to help. Retire your nanopore system and get special pricing on Revio. See offer: #PacBio #Revio
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@PacBio
PacBio
2 months
Reveal more for less with groundbreaking savings on #Revio system. Perfect for large studies, Revio captures all types of genomic variation and full-length views of transcripts. Limited time, bring Revio to your team at ~50% the upfront cost. See how:
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@PacBio
PacBio
4 years
E is for evolution! The evolution of the new Sequel IIe System includes increased computational capacity & on-instrument data processing to directly produce highly coveted, highly accurate #HiFiReads -- saving users time & money. Learn more:
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@PacBio
PacBio
3 years
Happy Friday! As a reward for getting through the week, we'd like to show you the amazing photography of @TimFlach These two made us think of our friends at @genomeark and @bat1kgenomes . Enjoy, @erichjarvis & @Sonja_Vernes ! #TGIF #naturerocks
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@PacBio
PacBio
5 years
With the release of the Sequel II System earlier this year, it is now affordable for scientists to access highly accurate long-read sequencing data. DYK we've added enhancements already? Find out more in a webinar w/ product guru Marty Badgett next Wed.
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@PacBio
PacBio
1 year
We are humbled that so many customers believe in the power of HiFi. In just 76 days since we announced #Revio , we have already received 76 system orders! We can’t wait to see what the #genomics community will accomplish with this game-changing platform.
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@PacBio
PacBio
4 years
Holy exquisite genomes Batman! The genetic basis of bats’ superpowers revealed in @nature by @bat1kgenomes . Congrats to @EmmaTeeling1 @Sonja_Vernes @hillermich & all involved. Proud to support the generation of high quality bat genomes w/PacBio sequencing:
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@PacBio
PacBio
3 years
LATEST: We’ve always known that high quality, long reads begin with high quality HMW DNA 🧬. That’s why today’s news is so important: #HiFiSequencing #DNAextraction #acquisition @circulomics
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@PacBio
PacBio
7 months
Say goodbye to yesterday’s RNA-Seq — say hello to Kinnex. Explore the cost-effective, scalable RNA solutions provided by the new Kinnex kits. #PacBio #ASHG23 #ASHG2023
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@PacBio
PacBio
1 year
📢 BREAKING: #Revio early-access launch is a 'go'. Thrilled to see the first of many more Revios to ship! #PacBio #AGBT23
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@PacBio
PacBio
7 months
Thrilled to see so many friendly faces at the #PacBio party. What a great way to celebrate the #ASHG23 community!    #ASHG2023
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@PacBio
PacBio
1 year
Just like The Force, our genomes are both powerful and mysterious. Unleash the full potential of your research with #Onso and #Revio , and explore the dark regions of the genome. May the force of genomics be with you! #MayThe4th #PacBio
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@PacBio
PacBio
3 years
How to improve the accuracy of #DeepVariant even further? Tackle phasing. See how the @GoogleHealth team improved their popular variant caller to make the most of #HiFiReads with a new haplotype channel.
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@PacBio
PacBio
1 year
The results are in! Long-read sequencing named 2022 Method of the Year by @naturemethods . A win for our customers and the scientific community- let's keep the discoveries coming in 2023! #Revio #PacBio
@naturemethods
Nature Methods
1 year
It's finally here!! Our Method of the Year 2022 is....long-read sequencing! 🎉 Read our (free!) Editorial to learn why we felt the time was right to select this class of powerful technologies as the Method of the Year.
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@PacBio
PacBio
4 years
Is it possible to generate truly high-quality, long-read data from minuscule amounts of DNA? Absolutely, thanks to our new kit for ultra-low DNA input, which enables whole genome amplification starting from as little as 5 ng of genomic DNA.
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@PacBio
PacBio
3 months
Start your year with a win: Bring in long reads, accuracy, uniform coverage, and native methylation calling – Revio system at ~50% less up front with reagent bundles. See the offer:
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@PacBio
PacBio
3 years
🌱 A complete de novo plant genome generation workflow that starts from plant tissue samples & produces high-quality draft genomes w/ relatively modest laboratory & bioinformatic resources... within 7 days? Check out #LeafGo by @kaust_corelabs 🌱
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@PacBio
PacBio
3 years
“The ability to find so many variants that were previously missed is exciting, + holds great promise for diagnostic testing in the future.” See what Greg Cooper & colleagues at @hudsonalpha found when they applied #HiFiReads to unsolved #raredisease cases.
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@PacBio
PacBio
3 years
Best stuff is in the Supplement! HGSVC says 'As sequencing tech & assembly algorithms continue to evolve, HiFi sequencing has been predicted to predominate because accuracy & higher depth will afford access to even more previously inaccessible regions.'
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@PacBio
PacBio
3 years
Extracting DNA for sequencing isn’t always as straightforward as lyse, precipitate, wash, suspend. In this #Sequencing101 blog, we share tips, tricks, & protocols to help make your DNA isolation easier. Check it out & share widely!
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@PacBio
PacBio
11 months
Congratulations to the Uppsala Genome Center (UGC) from @ngisweden for winning our recent customer contest with their creative and inspiring name for their Revio system: Rosi! We love to see the team sporting PacBio colors with their #Revio . Congratulations! #PacBio
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@PacBio
PacBio
4 years
“We are now embarking on an era where all genetic variation in an individual will be completely discovered. Hundreds, and ultimately thousands, of new human reference genomes will be produced.” @glennis_logsdon @mrvollger & Evan Eichler in @nresearchnews
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@PacBio
PacBio
4 years
“SVs are increasingly being recognized as an important class of variants, which need to be considered in evolutionary, population & clinical genomics.” Summary of two structural variation review papers: @UM_Genetics @BCM_HGSC @NatureGenet @GenomeBiology
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@PacBio
PacBio
3 years
Oxford, Liverpool, Edinburgh...and beyond! The UK is now well equipped for #SMRT Sequencing, w/ several new Sequel II & IIe Systems installed at three top centres: @OxfordGenomics @CGR_UoL @edgenome We can't wait to see what discoveries they will enable!
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@PacBio
PacBio
3 months
Promise: Q40. Reality: See below. . @TGen hits >Q50 on most bases with real liquid biopsy samples on #Onso . #AGBT #AGBT24 #PacBio
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@PacBio
PacBio
2 years
We look forward to seeing what @radboudumc can accomplish with their addition of 2 new #PacBio Sequel IIe Systems. Their work with our #SMRTsequencing is crucial in identifying hidden variants that cause #rarediseases . Learn more here: 📸: @ahoischen
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@PacBio
PacBio
10 months
The first #Revio has been installed in Japan, and we can't wait to see the exciting discoveries that will be made at @KGenomeu . #PacBio #icg2023
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