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PLOS Biology, the PLOS flagship journal in life sciences, is a highly selective open-access, peer-reviewed general biology journal @PLOSBiology @fediscience .org

San Francisco/ Cambridge, UK
Joined December 2009
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@PLOSBiology
PLOS Biology
6 years
"Scooped"? We prefer to call it "complementary research," recognising its important role in reproducibility of science. Come to #PLOSBiology within 6 months of "scooping" and we'll consider it. See our new policy here:
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@PLOSBiology
PLOS Biology
6 years
Super-fast, low-cost, low-tech prep of DNA or RNA from plants/animals/bugs in 30 seconds, using filter paper or paper towelling #PLOSBiology
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@PLOSBiology
PLOS Biology
1 year
Floating life ( #neuston ) & trash cluster in the #GreatPacificGarbagePatch . High neuston abundance was only known in the #SargassoSea , but @this_fionachong @RebeccaRHelm &co reveal high densities of floating life in the plastic-rich GPGP #PLOSBiology
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PLOS Biology
3 years
The mysterious 'neuston' ecosystem at the ocean’s surface includes organisms like the seaweed Sargassum, floating barnacles, snails, nudibranchs & cnidarians; @RebeccaRHelm explores threats to its wellbeing and importance of further research #PLOSBiology
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PLOS Biology
5 years
Want to make your data look beautiful, but without learning coding skills? Try #PlotsOfData - an intuitive web-based tool for state-of-the-art #DataViz - Marten Postma & @joachimgoedhart in #PLOSBiology app: paper:
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PLOS Biology
6 years
Do our #mitochondria run at 50 degrees? Temp-sensitive probe suggests they run 10 deg hotter than cells #PLOSBiology & read Nick Lane's take on the implications & problems:
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PLOS Biology
4 years
More secrets from the jellyfish that yielded GFP, transforming the study of living cells. @LABrechaun @NathanShaner &co reveal that A. victoria and its Aussie cousin encode a diverse set of fluorescent proteins, incl the brightest yet described PLOSBiology
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PLOS Biology
6 years
Which genes are hot... and which genes are not? Massive study of gene-specific bias in publication and funding shows that most human research is done on just 10% of genes, and predicts the most promising neglected gems #PLOSBiology
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PLOS Biology
6 years
Nitrogen-fixing slime frees corn from fertilizer. Indigenous #Mexican maize produces slime on its aerial roots that hosts nitrogen-fixing #bacteria that provide up to 82% of the #plant ’s nitrogen requirements #PLOSBiology
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PLOS Biology
11 months
In honor of #WorldOceanDay , we’re highlighting some of our most exciting research and commentary on #MarineBiology and #ocean research. This beautiful study from @RebeccaRHelm &co catalogues life in the North Pacific “Garbage Patch”
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PLOS Biology
10 months
What is the cost of science being conducted in English? @tatsuya_amano &co reveal that non-native English speakers spend more effort than native speakers in conducting scientific activities (reading, writing, preparing presentations...) #PLOSBiology
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PLOS Biology
4 years
Editorial: We need leaders that believe in scientific evidence PLOS Biology cannot stand by in silence while trust is undermined by those elected to make decisions in the name of and for the benefit of society We urge you to vote wisely!
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PLOS Biology
2 years
Most RNA #viruses cause acute infections, but phenomena such as #LongCovid suggest that viral #RNA can persist after recovery. In this Unsolved Mystery, Diane Griffin explores the meaning, origins and consequences of persistent viral RNA. @JohnsHopkinsSPH
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PLOS Biology
2 years
#SARSCoV2 doesn't like it hot. #COVID19 involves onset of fever, raising body temp to 38-41°C; study shows that raising temp to 40°C limits replication of #SARSCoV2 in respiratory airway cultures, independently of interferon-mediated defences #PLOSBiology
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PLOS Biology
4 years
A chromosome carrying a color patterning supergene has spread rapidly through a population of African monarch #butterflies by hitchhiking with a male-killing #endosymbiont (hitchhiking between unlinked genomes) @simonhmartin &co in #PLOSBiology
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PLOS Biology
3 years
Want to attract computational biologists to your project or to your department? @DrAnneCarpenter @FertigLab & 14 other #compbio folks explore solutions to problems faced in career advancement, publication & grant review #PLOSBiology
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PLOS Biology
5 years
Silkworms normally only eat mulberry leaves; can we make them love apples? A genetic study reveals that mutation of a single bitter gustatory receptor GR66 converts the #silkworm , a typical monophagous #insect , into a polyphagous species #PLOSBiology
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PLOS Biology
3 years
For junior researchers, the challenges of the #COVID19 pandemic extend beyond lost time and are career-threatening. @TLowePower @DrLouiseDyson & @ampolter argue that without intervention, academic science could lose a generation of talent #PLOSBiology
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PLOS Biology
5 years
Why spend €1000s on a #spectrophotometer when you can make one for <€5? Plans for 3D-printed cuvette holder with LED block, which with smartphone Ambient Light Sensor makes a high-performance, low-cost spectrophotometer. Also #Lego version! #PLOSBiology
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PLOS Biology
6 years
Analysis of 36 million authors across >6000 journals reveals woeful #GenderGap across #STEMM disciplines, "likely to persist for generations, particularly in #surgery , #computerscience , #physics , and #maths " #PLOSBiology
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PLOS Biology
1 year
#Viruses infecting #bacteria & #archaea are often identified via metagenomics, but information regarding #phage hosts is lost. @simroux_virus &co present iPHoP, a new tool to maximize host prediction for #metagenome -assembled virus genomes #PLOSBiology
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PLOS Biology
2 years
Many bacterial & archaeal defense systems are encoded by mobile genetic elements. @eprocha & @dbikard argue that this challenges our ideas of their role in cells: Who's defending? From what? And what's the role of the cellular genome in this? #PLOSBiology
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PLOS Biology
3 years
The mysterious 'neuston' ecosystem at the ocean’s surface includes organisms like the seaweed Sargassum, floating barnacles, snails, nudibranchs & cnidarians; @RebeccaRHelm explores threats to its wellbeing and importance of further research #PLOSBiology
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PLOS Biology
5 years
@micheome FYI that's exactly our attitude at @PLOSBiology - submit in any (reasonable) format!
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PLOS Biology
3 years
The mysterious 'neuston' ecosystem at the ocean’s surface includes organisms like the seaweed Sargassum, floating barnacles, snails, nudibranchs & cnidarians; @RebeccaRHelm explores threats to its wellbeing and importance of further research #PLOSBiology
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PLOS Biology
4 months
Statistical #PowerAnalysis currently dominates #ExperimentalDesign . In this Essay, @itchyshin &co argue that we should move away from the current focus on power analysis and instead encourage smaller scale studies & collaborative projects #PLOSBiology
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PLOS Biology
4 years
A single-cell transcriptomic study of the immune system of the cancer-resistant #NakedMoleRat reveals that it lacks natural killer (NK) cells, thought crucial for cancer resistance. Its genome lacks NKC expansion, and only has 2 MHC-I genes #PLOSBiology
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PLOS Biology
5 years
Why can #Toxoplasma only have sex in cats? #Cats are the only mammals to lack delta-6-desaturase enzyme, giving them high levels of linoleic acid. Inhibiting the enzyme in mice and feeding them linoleic acid allows Toxo to have sex in mice #PLOSBiology
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PLOS Biology
8 months
#Bats are natural hosts for #viruses that cause higher case fatality rates in humans than do #zoonoses derived from any other source. @caraebrook @bootslab &co build a nested within-host, population-level model to explain this phenomenon #PLOSBiology
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PLOS Biology
2 years
Massive survey of >5k journals explores relationship between hyper-prolific authors & journal editorial teams, finding a subset of journals that show signs of nepotism @NaudetFlorian @IoanaA_Cristea @dmoher @deevybee @Clara_Locher &co #PLOSBiology
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PLOS Biology
6 months
Why are we still publishing complicated descriptions of #DNA constructs when they can be fully sequenced? @thuronyi @erika_alden_d & @barricklab suggest that outdated #methods narratives should be replaced with DNA #sequence files in publications.
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PLOS Biology
10 months
What is the cost of science being conducted in English? @tatsuya_amano &co reveal that non-native English speakers spend more effort than native speakers in conducting scientific activities (reading, writing, preparing presentations...) #PLOSBiology
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PLOS Biology
3 years
. @PeterHotez argues that #COVID19 has exposed how a rising tide of anti-science rhetoric & activities can exploit society's vulnerabilities to an infectious disease... has #AntiScience extremism become as big a threat as the virus itself? #PLOSBiology
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PLOS Biology
5 months
Starvation turns some #fungi into #nematode -eating #predators . Study by @fungi_worms &co reveals increased DNA replication, translation & secretion as worm traps develop; DUF3129 proteins on trap surfaces are involved in worm #adhesion #PLOSBiology
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PLOS Biology
5 years
Cheaper, easier, safer: #OpenSource DNA/RNA purification & handling protocols based on functionalised magnetic beads, aiming to transform the practice & economics of life science research #PLOSBiology @teamBOMBbio
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PLOS Biology
2 years
Homeostatic plasticity in #neurons involves translation & degradation. Study reveals that RNA-dependent synergy between #translation , #degradation & #miRISC remodeling is needed for synaptic homeostasis during changes in network activity #PLOSBiology
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PLOS Biology
5 years
The ongoing #evolution inside all of us: pop'n genetic analysis of human gut #bacteria reveals short-term evolution within individual bacterial species, both within each human host & across the population @nanditagarud @benjaminhgood &co #PLOSBiology
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PLOS Biology
1 year
Plasmids manipulate host cells to their benefit. @catriona1392 @brockhurstlab &co describe a #plasmid -borne translational regulator that subverts ecological traits in #bacteria , inducing community organization & promoting plasmid transmission #PLOSBiology
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PLOS Biology
2 years
To what extent does #breathing modulate brain oscillations at rest? Human MEG study by @danlikesbrains & @Joachim__Gross identifies a widespread brain network of neural oscillations that are coupled to the respiratory rhythm #PLOSBiology
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PLOS Biology
6 years
No more paywalls for European scientific research: president of @ScienceEurope , @marcschiltz1 , presents #cOAlitionS , mandating #OA publication from Jan 2020 (also pubbed @FrontNeurosci @PLOSMedicine ) #PLOSBiology
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PLOS Biology
1 year
Viruses are the most abundant biological entity in the #ocean . In this #PLOSBiology Essay, @vincentflora @vardilab discuss interactions between hosts and #viruses in the ocean and their relevance for global ocean ecosystem function in a changing climate.
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PLOS Biology
3 years
Female gametophytes of angiosperms contain cells with distinct functions (e.g. pollen tube attraction & fertilization). Live-cell imaging & transcriptomics of single female gametophyte cells reveal how cell fates are specified in Arabidopsis #PLOSBiology
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PLOS Biology
6 years
Nitrogen-fixing slime frees corn from fertilizer. Indigenous #Mexican maize produces slime on its aerial roots that hosts nitrogen-fixing #bacteria that provide up to 82% of the #plant ’s nitrogen requirements #PLOSBiology
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@PLOSBiology
PLOS Biology
6 years
"Scooped"? We prefer to call it "complementary research," recognising its important role in reproducibility of science. Come to #PLOSBiology within 6 months of "scooping" and we'll consider it. See our new policy here:
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PLOS Biology
8 months
Cells can counteract #aging by transmitting mitochondria asymmetrically. This study in #yeast shows how oxidatively damaged #mitochondria are selectively retained in the mother cell to prevent inheritance by the next generation. #PLOSBiology
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PLOS Biology
2 years
As the legendary #LTEE baton is passed on to @barricklab , check out this conversation between @RELenski and @DynamicEcology published in @PLOSBiology back when the LTEE was a mere 27 years (or 60,000 generations) old...
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PLOS Biology
5 years
How do birds position their feathers so accurately? New study reveals a spreading wave of ectodysplasin A, which triggers dense mesenchyme to begin feather patterning. Flightless birds have lost the EDA/cell density interaction #PLOSBiology
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PLOS Biology
3 years
Jumping spiders can distinguish animate from inanimate objects based solely on visual motion characteristics ("biological motion" of a body comprising jointed segments) — previously known only in vertebrates @Massimo_De_Agro @RoesslerDaniela #PLOSBiology
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PLOS Biology
4 years
Illustrating the pandemic. Molecular artist @dsgoodsell &co describe how visually striking illustrations of coronaviruses can capture our knowledge of the field and provide a touchstone for outreach & education about these pathogens #COVID19 #PLOSBiology
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PLOS Biology
7 months
"I'll have what she's having!" Why do females choose particular mates? @EmilyHDuVal @servedio1 &co propose that mate choices rely on context-dependent social information, explaining major puzzles in the study of #SexualSelection . #PLOSBiology
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PLOS Biology
5 years
Brewer's #yeast has been used to make fermented beverages for millennia. Genome analysis of #beer and other yeast strains shows that beer yeast have a polyploid admixed origin derived from European & Asian #wine populations @justinfay &co in #PLOSBiology
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PLOS Biology
3 years
Which #COVID19 vaccination strategy? Two doses 3-4 weeks apart... or delay the 2nd dose? A modelling study by @Alison_Galvani &co shows that delaying the 2nd dose can maximize the benefits of vaccination programs under certain conditions #PLOSBiology
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PLOS Biology
3 years
Neural oscillation... or not? Using a normal form oscillator model, @KeithD11 & @FlorAssaneo refute the most commonly held ideas of how an oscillator should behave, generating a series of cautionary examples to emphasize their findings #PLOSBiology
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PLOS Biology
3 years
NLRs are the main class of disease resistance genes in plants. @JiorgosKourelis @KamounLab &co present #RefPlantNLR , a comprehensive reference dataset of 481 experimentally validated NLR immune receptors from 31 genera of flowering plants #PLOSBiology
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PLOS Biology
1 year
@arjunrajlab For the record, @PLOSBiology do *not* do this. Reviewer exclusions will be respected if possible. If a large number of relevant experts are excluded, however, we'll ask the authors to rank those exclusions (and/or justify them), and may have to invite the "mildest."
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PLOS Biology
2 years
A study of the relationship between antibiotic use & resistance shows that #AntibioticResistance peaks in the winter/spring and correlates most with use of penicillins & macrolides (antibiotics with winter-peaking use) @yhgrad @mlipsitch &co #PLOSBiology
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PLOS Biology
2 years
#Cryptosporidium is a leading global cause of #diarrhea . @elisetweetsbio @striepenlab &co reveal its program of asexual & sexual commitment & replication, requiring textbook-changing revision of the lifecycle of this important #parasite #PLOSBiology
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PLOS Biology
3 years
Surveillance for #SARSCoV2 variants is important, but sequencing is not always practical or affordable. @VogelsChantal @JosephFauver @NathanGrubaugh &co present a multiplex qPCR that can distinguish among current SARS-CoV-2 variants of concern #PLOSBiology
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PLOS Biology
2 months
Mammals have 6 conserved #actin isoforms with nonredundant functions. @koenvddries @syncellbiolab &co present IntAct, a tool to study actin isoform localization, dynamics & molecular interactions across species in fixed & living cells #PLOSBiology
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PLOS Biology
4 years
Seeing is feeling? Rod photoreceptors are mechanosensitive; study reveals that rod receptorss express mechanosensitive channels, that mechanosensitivity is crucial for phototransduction, and that outer segments shorten in response to light #PLOSBiology
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PLOS Biology
6 years
Which genes are hot... and which genes are not? Massive study of gene-specific bias in publication and funding shows that most human research is done on just 10% of genes, and predicts the most promising neglected gems #PLOSBiology
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PLOS Biology
3 years
Why is #LymeDisease common in the northern US, but rare in the south? Howard Ginsberg, @JTsao1 &co show that it's because the ticks attach mainly to rodents (good hosts for Lyme bacteria) in the north, and lizards (poor hosts) in the south #PLOSBiology
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PLOS Biology
3 months
How are olfactory #cilia and sensory neuron differentiation regulated? This study of #zebrafish & mice shows that the #forkhead domain transcription factor Foxj1 is critical for #OlfactoryCilia and #SensoryNeuron differentiation #PLOSBiology
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PLOS Biology
9 years
Bar graphs hide the distribution of continuous data - time to kill them off! #PLOSBiology http://t.co/gASIcrpm5b http://t.co/7VN5OrRyX2
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PLOS Biology
2 years
In all living organisms, cells must resist mechanical stress to survive. This study in #Arabidopsis reveals that the candidate cell wall #mechanoreceptor FERONIA and #microtubules independently contribute to this mechanical feedback @RDPlab #PLOSBiology
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PLOS Biology
5 years
Using #monkeyflower genome sequences to reconstruct patterns of evolution over 1,000,000 years of divergence, @matt_streisfeld &co show that natural selection plays a key role in driving genetic differentiation between emerging species #PLOSBiology
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PLOS Biology
5 years
Brewer's #yeast has been used to make fermented beverages for millennia. Genome analysis of #beer and other yeast strains shows that beer yeast have a polyploid admixed origin derived from European & Asian #wine populations @justinfay &co in #PLOSBiology
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PLOS Biology
3 years
Combo of entry assays & live virus suggests #SARSCoV2 may have a broad host-range; its spike protein can use broad range of ACE2 receptors to enter cells, & sequence may have changed as it jumped to humans @Morbillivirus &co @Pirbright_Inst #PLOSBiology
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PLOS Biology
11 months
Movement proteins enable cell-to-cell transfer of #plant RNA & DNA viruses via #plasmodesmata . @Butkovic_A @mkrupovic &co show that 30K movement proteins originated from #virus #JellyRoll capsid proteins, emphasizing the key role of exaptation #PLOSBiology
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PLOS Biology
6 years
Super-fast, low-cost, low-tech prep of DNA or RNA from plants/animals/bugs in 30 seconds, using filter paper or paper towelling #PLOSBiology
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PLOS Biology
3 years
Employing optimal computational methodology in cryo-electron tomography is not always easy; @AlisterBurt &co (Gutsche lab) provide a set of tools and a complete guide to obtaining high-resolution structures from cryo-ET data #PLOSBiology
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PLOS Biology
6 years
Teaching #reproducibility . New #graduate course highlighting essential methods for transparent & reproducible research - provides adaptable #OpenEducation resources for integration into graduate curricula #PLOSBiology
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PLOS Biology
7 months
Brain #connectivity : physical links between regions, synchronized activity, or molecular similarities? @JustineYHansen @misicbata &co integrate seven connectivity blueprints to characterize inter-regional relationships in the human #cortex . #PLOSBiology
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PLOS Biology
6 years
What made human gestation longer? An anthropoid-specific retroviral insertion regulates the expression of CRH, a placental protein associated with human birth timing; mice bearing this inertion have longer #gestation times #PLOSBiology
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PLOS Biology
1 year
In a new #PLOSBiology study, @teresa_omeara @microbialfaith &co show that healthy people are reservoirs for diverse strains of the yeast C. albicans, and that these commensal strains retain the capacity for virulence #microbiology
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PLOS Biology
7 years
60 yrs on: the legacy of #FrancisCrick 's conceptual leap - the "Central Dogma" - by @matthewcobb in #PLOSBiology
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PLOS Biology
3 years
Neural stem cells can transfer mitochondria via extracellular vesicles to target cells both in vitro & in vivo, suggesting a signaling mechanism used by NSCs to modulate physiology & metabolism of target cells @Dr_LPJ @Pluchinolab &co #PLOSBiology
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PLOS Biology
3 years
Making a new primate phylogeny, @farming_bugs @bq_minh @RobLanfear @3rdreviewer &co adapt a method for detecting ancient introgression to genome-scale data, revealing multiple previously unknown examples of hybridization between primate spp #PLOSBiology
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PLOS Biology
3 years
Vampire bats meet for dinner. @SimonRipperger & Gerry Carter show that social bonds in #VampireBats typically defined by cooperative interactions within the roost also extend beyond the roost and may provide benefits when foraging for blood #PLOSBiology
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PLOS Biology
6 years
Why does #exercise reduce #appetite ? Because the #hypothalamus heats up! Raised temperature in brain is detected by TRPV1-like thermoreceptors in proopiomelanocortin neurons in arcuate nucleus #PLOSBiology
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PLOS Biology
11 months
Evidence suggests that some #insect species might feel #pain . @AndrewCrump94 @matilda_gibbons @Bee_Bytes @birchlse & @LChittka argue that researchers need to consider the welfare implications of these findings for insect experiments #PLOSBiology
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PLOS Biology
2 months
Bees are a powerful system to probe host-gut #microbiota interactions. @a_chhun @PEngellab @YSchaerli &co engineer a native bacterial #symbiont of the #HoneyBee to non-invasively sense & report exposure to molecular cues inside the gut #PLOSBiology
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PLOS Biology
3 years
During gastrulation, mesoderm “invades” the developing embryo. Study reveals that its capacity for fast migration while remaining cohesive is triggered by down-reg of cell contractility via expression of two tissue-specific myosin regulators #PLOSBiology
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PLOS Biology
5 years
The #RequestAWomanScientist resource, launched Jan 2018 through @500womensci organization, represents an important step in increasing the diversity of voices represented as scientists in the public & scientific communities #PLOSBiology
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PLOS Biology
9 months
How do intracellular pathogenic #bacteria scavenge host nutrients? @KMitosch @kiran_r_patil @TypasLab &co use 13C-mannitol to track #Salmonella 's #metabolism when growing inside host cells, revealing its food sources & #MetabolicPathways #PLOSBiology
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PLOS Biology
2 years
A spotters' guide to E. coli phages. This resource for the community is representative of natural #Ecoli #phage diversity and has been extensively characterized phenotypically & genomically @AHarms485 @phagemuffin @AisyluShaidull1 &co #PLOSBiology
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PLOS Biology
2 years
How is #pain represented? A single brain area, multiple systems or throughout the brain? Novel approach using large multi-study dataset shows multiple cortical & subcortical systems are needed to decode pain intensity @bogpetre @torwager &co #PLOSBiology
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PLOS Biology
4 years
Ancestral land plants lacked leaves; these evolved independently in each lineage during the lower Palaeozoic. Study of liverwort Marchantia reveals that each time they evolved they used the same molecular mechanism to control leaf development #PLOSBiology
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PLOS Biology
7 years
The usefulness and impact of life science data will depend on robust & unique identifiers #PLOSBiology
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PLOS Biology
6 years
The release of @CellProfiler version 3.0 adds the ability to analyze images in 3D; this article describes the tech improvements to this open-source software that will make you want to upgrade #PLOSBiology @DrAnneCarpenter
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PLOS Biology
5 years
Differentiation in mother of all animals? 3D EM of #choanoflagellates & #sponge choanocytes reveals remarkable variety of cell architecture, suggesting that cell type differentiation may have been present in stem lineage leading to animals #PLOSBiology
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PLOS Biology
9 years
P-values: history, usage and abusage. P-hacking - we should we do about it? #PLOSBiology http://t.co/vvjp8qyFoH http://t.co/AAOOjtAl2h
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PLOS Biology
5 years
Microglia are confined to the central nervous system, right? New study shows that after spinal root injury, #microglia can exit the CNS to clear debris; when they return, the microglia are altered and can travel to distal areas like the brain #PLOSBiology
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PLOS Biology
4 years
Drinking animal milk is a textbook example of gene-culture coevolution, but how did lactase persistence emerge? The mutation rapidly spread through Eurasia ~3000 BP, but Asian herders adapted culturally, so why did Europeans adapt genetically? #PLOSBiology
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PLOS Biology
6 years
Nitrogen-fixing slime frees corn from fertilizer. Indigenous #Mexican maize produces slime on its aerial roots that hosts nitrogen-fixing #bacteria that provide up to 82% of the #plant ’s nitrogen requirements #PLOSBiology
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PLOS Biology
20 days
Endosymbiosis is common and has been important in the #evolution of complex life, but its mechanistic origins remain unclear. This Essay explores the theory and experimental evidence for trade-offs in the early-stage evolution of #symbiosis .
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PLOS Biology
1 year
Within hours of #neuron birth, terminal differentiation genes are transcribed, but not translated. In #PLOSBiology , @TheHomemLab reveals that these transcripts are only translated days later in a way that coordinates with developmental stage in #Drosophila
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PLOS Biology
5 years
Somatic mutations in plants: rates of accumulation vary between different parts of a plant, with lower rates when mutations have greater potential longevity (such as in leaves) than in more disposable structures (such as petals) #PLOSBiology
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PLOS Biology
2 years
DNA life preservers. #Caulobacter crescentus produces a #prophage -like gene transfer agent that mediates survival in DNA damaging conditions by providing genomic DNA from donor cells for #recombination -based repair in recipients @michael_laub8 #PLOSBiology
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