Alexander Harms @AHarms485 Twitter profile

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Alexander Harms

@AHarms485

3 years

Good morning to everyone from team "science with a view" 🌅🌁

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Alexander Harms

@AHarms485

1 year

Big news: My Starting Grant was FUNDED, so my group is moving to ETH Zürich @ETH_en in 2023 where we will continue to study the molecular biology of cool new phages. We will be based at D-HEST together with our friend @MartinLoessner and his group. Great times ahead 🍾💰🧫! 1/2

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Alexander Harms

@AHarms485

2 years

Achievement unlocked - first phage isolated that has no relevant similarity to anything previously known (and the genome is big, >>100kb!). Best whole-genome BLAST hit has 0% coverage / 70% identity due to a short 100bp stretch of homology in a tail gene. Exciting! 😁🧬🔥

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Alexander Harms

@AHarms485

1 year

Happy and honored to be appointed as assistant professor of molecular phage biology by ETH Council! Thank you to all students and my mentors for the support. Our group at D-HEST will (re)start on April 1st. 🤗🍻🎓

Joël Mesot

@Joel_Mesot

1 year

👏 Congratulations to 14 new profs appointed by the @ETH_Rat ! @bernd_bickel @Cindy_brGDGT @AllardDuursma @AHarms485 @Chakothra @natalia_pikor Mikaela Iacobelli @ArosioLab_ETH Caroline Dorn @debocklab Andreas Fichtner @petra_schmid Hans Jakob Wörner @DS3Lab

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Alexander Harms

@AHarms485

1 year

What is the most annoying part of molecular biology and why is it minipreps?

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Alexander Harms

@AHarms485

2 years

Bacterial immunity is so satisfying to watch 🦠🛡️! The plates below show dilutions of twelve phages on a reference host (left) vs. some exciting anti-phage defense (right). No shaky ambiguous phenotypes like in some other areas of microbiology 😅...

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Alexander Harms

@AHarms485

2 years

Do you need a field guide on Escherichia coli phages or an assorted collection of them as a tool for genetic or evolutionary studies? Here we present the final version of our “BASEL collection” in @PLOSBiology 👇😁. Short thread 1/6

Systematic exploration of Escherichia coli phage–host interactions with the BASEL phage collection

This study presents the BASEL collection of phages that infect the model bacterium Escherichia coli; this resource for the community is representative of natural E. coli phage diversity and has been...

journals.plos.org

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Alexander Harms

@AHarms485

3 years

Totally in love with these phages (new and undescribed group infecting E.coli) that form a "crown" of clear lysis around their plaques. Exciting! 🤩🧫 The weird thing is that these "crowns" are discontinuous with the plaques. Anybody ever saw anything like that or has ideas?

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Alexander Harms

@AHarms485

2 years

"going to the lab early for minipreps" (before the students use their benches) is the new "getting up early to work before the kids get up" 😆🧪🧪🧪

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Alexander Harms

@AHarms485

4 months

Interested in how phages deal with dormant bacteria? After a looong and difficult peer review process Enea @phagemuffin presents the final version of our paper. 😁🔥👇🏼

Enea Maffei

@phagemuffin

4 months

Looks like 2024 is off to a good start! After two years, the definitive version of this story is out! The process was long and extenuating but definitely worth it. Of course, we didn’t leave things as they were, and some updates were made to the original manuscript (a short 🧵)

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Alexander Harms

@AHarms485

1 year

Big news #2 : After a pleasantly old-fashioned process I obtained the habilitation in microbiology as final step of my career at @UniBasel @biozentrum . Very proud of this blessing for research and teaching 😁🧑🏻‍🎓! For locals: Public inauguration + farewell lecture is on Friday 👇🏼.

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Alexander Harms

@AHarms485

2 years

These phages here confirmed once more that "trying out various things which vaguely make sense" is the superior problem-solving strategy in molecular biology... too often there are so many unknown parameters that one can simply not build a rational road to the goal. 🛠️🧫😅

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Alexander Harms

@AHarms485

1 year

First plaques of the new lab - and many more to come! After 2022 was the year of grants 2023 needs to be the year of papers... stay tuned, the students have many nice stories to be published! 😁🧫📝

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Alexander Harms

@AHarms485

3 years

Finally – first preprint of my group at @Biozentrum Basel @NCCR_AntiResist ! We describe the BASEL collection of representative E. coli phages from all major families and report their systematic phenotypic and genomic characterization. Thread 1/6 🧫🧪🎊🎉

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Alexander Harms

@AHarms485

1 month

Today the first year of my professorship at ETH Zürich ends - incredibly proud of what we have built up and achieved together! Four more years to find a new position before the current one expires... 🎂⏳🤔

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Alexander Harms

@AHarms485

18 days

If you are in the area next Monday and curious about molecular phage biology, join us for my inaugural lecture at @ETH_en Zürich - it's public! 🧬🦠👇🏼

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Alexander Harms

@AHarms485

2 years

Classic phage M13 is just a miracle of life - a complete virus with a genome smaller than some dumb plasmids used for cloning (6.4kb). ❤️🍝🧬

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Alexander Harms

@AHarms485

3 years

Last week I visited a Pestalozzi school camp and discussed with the kids about phages in environment and clinics. Given the camp's aim of linking science + art, we also colorized some TEM pictures. I was stunned by the kids' individualism and creativity! Example before / after 👇🏼

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Alexander Harms

@AHarms485

5 months

Paper-accepted selfie with Enea @phagemuffin 🥂🚀 - after almost two years of difficult peer review. Very proud and grateful to all who contributed! Enea will tell you all about the science when it's out 😁🔥.

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Alexander Harms

@AHarms485

1 year

Big moving day today - that's our lab in boxes, minus all the stuff that requires cooling 🙃🎁. Keep your fingers crossed for smooth shipping!

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Alexander Harms

@AHarms485

2 years

After the celebratory opening today our exhibition of colorized phage TEM images at @biozentrum @UniBasel_en is now open for the public 🥂🔬🎨. So proud we could combine research, teaching, and outreach #SciComm with art by Fabienne @fabi_est_ ! More info:

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Alexander Harms

@AHarms485

2 years

New preprint out today! Check out the work of my PhD student Enea @phagemuffin who shows how our newly isolated P. aeruginosa jumbo phage Paride can directly kill dormant, antibiotic-tolerant bacteria. Like a warm knife through butter! 🔥🔥🔥

Enea Maffei

@phagemuffin

2 years

It is with great excitement (and some pride) that I reveal what has been the main subject of my PhD for the past 3 years! Spoiler alert: it is about phages and antibiotic tolerant bacteria! Wanna know more? Continue reading (a🧵) (1/9)

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Alexander Harms

@AHarms485

1 year

New cool gadget combines two of the best things and turns every beer bottle into a phage 😎🍺.

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Alexander Harms

@AHarms485

1 year

New desk setup finished! Great functionality and top office neighbor @MattDunne_1 , though I miss my 9th floor view over Alsace from @biozentrum ...

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Alexander Harms

@AHarms485

2 years

Last ten days were tough: ✅ daughter born (all good!) ✅ big grant submitted ✅ @yannik_heyer graduated (excellent!) ✅ habilitation submitted Cheers on the weekend! 😊🍻☀️

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Alexander Harms

@AHarms485

2 years

Big exhibition of colorized phage TEM images at @biozentrum @UniBasel_en starting soon - open for general public from August 19th! First print arrived today 😁. Images taken by us (+high schoolers) from our phages, colorization by the amazing Fabienne Estermann @fabi_est_ 👩‍🔬👩🏼‍🎨!

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Alexander Harms

@AHarms485

2 years

#PhageOfTheWeek is back with T7, a killer virus that overpowers E. coli by frontal attack and massive replication 🫡🔥. Note the very large, fast-growing plaques of this phage that I imaged already after 8h before things get very messy. A 🧵 1/14

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Alexander Harms

@AHarms485

9 months

We discussed shipping strains today and it was surprising to me how much of it is still done in LB agar stabs. That is risky if genomic integrity matters - see paper below and this short thread 🦠📬👇🏼. 1/4

The uncertain consequences of transferring bacterial strains between laboratories - rpoSinstability...

Background Microbiological studies frequently involve exchanges of strains between laboratories and/or stock centers. The integrity of exchanged strains is vital for archival reasons and to ensure...

bmcmicrobiol.biomedcentral.com

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Alexander Harms

@AHarms485

6 months

The lab has been at ETH Zürich for almost a year now, and here you are witnessing the first transformation that I find time to do myself... please clap! 😁🧬🧫

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Alexander Harms

@AHarms485

2 years

With our high schoolers today: plasmids and phages. The F-plasmid defends E. coli against phage T7 (see F+ vs. F-) but it sensitizes cells to phages M13 and MS2 that bind its sex pilus ⚔️🧫. T4 doesn't care 😁. Great discussions how good and bad are often context-dependent!

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Alexander Harms

@AHarms485

3 years

We finally completed our arrival in the new institute building because the students now customized all benches with black cover. I don't know why white benches are standard, but everything - colonies, plaques, even microscopy slides - are much better visible on a dark background.

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Alexander Harms

@AHarms485

1 year

Fun observation of the day: The virulent phage in the second lane clears the turbid plaques of the phages in the adjacent lanes. I suspect very potent secreted lysins 🤔🧫. (these are a couple of new / unpublished phages on E. coli K-12)

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Alexander Harms

@AHarms485

3 years

Today was day 1 in the last year of my expiring junior PI position at @biozentrum - lots of exciting science with my student dream team and great colleagues, but all good things eventually end. Nobody knows what the future holds though I will for sure miss the view. 🧳🌆🌄

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Alexander Harms

@AHarms485

1 year

There is this new thing in my life - the commute (Basel to Zürich). So far I love it! Twice per day an hour of uninterrupted (!) office time plus the ascend to ETH Zürich with cute Polybähnli 😁🚞.

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Alexander Harms

@AHarms485

1 year

We are looking forward to amazing life + science in Zürich, but I think the views from the new @biozentrum institute building in Basel are just unbeatable 🌇🌄🌁... will be certainly missed!

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Alexander Harms

@AHarms485

1 year

After almost ten days of retreats, external lectures, and admin work it's the right moment for some quality time with the students in the lab 😁🧫🧪.

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Alexander Harms

@AHarms485

3 years

Temperate phages (forming prophages) often have light turbid plaques like these since lysogens are self-immune. See the one clear plaque of an obligately lytic mutant - it's the reason lambda's iconic lysogeny genes are cI, cII, etc. - c for clear plaque. Exciting in real life 👍🏼

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Alexander Harms

@AHarms485

2 years

We are beyond proud of MSc student Yannik @yannik_heyer 💪🏼💪🏼💪🏼. He will defend his thesis soon and then we lack the money to keep him... so he took control of the situation, crafted a really nice project proposal, and got it funded! 💰🍾

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Alexander Harms

@AHarms485

8 months

Very satisfying end of a great congress of the Swiss Society for Microbiology - for our work in research, teaching, and outreach at @biozentrum + @ETH_en I received the society's big prize ("Encouragement Award"). Many thanks to my group, mentors, and all friends for the support!

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Alexander Harms

@AHarms485

2 years

Teaching 20 high schoolers for two weeks: nothing happened 👍🏼. First punkrock show since two years: nothing happened 👍🏼. Being uncautious at a virology conference: Life loves irony. 🙄👇🏼

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Alexander Harms

@AHarms485

1 year

Many cool secrets at ETH Zürich main building - the locker of Albert Einstein is arranged as a little museum! 😎🎓

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Alexander Harms

@AHarms485

1 year

Phage isolation for a collaboration project - the excitement of new viruses never gets old! 🎁🧫😁 A luxury to take time for this but I just love it (new P. aeruginosa strain, ca. 2.5mL of sewage).

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Alexander Harms

@AHarms485

2 years

#PhageOfTheWeek is back with EmilieFrey (Bas61), a myovirus with a very broad lysis host range! Today we highlight a group of phages that have interesting biology but are ridiculously understudied, simply because they are missing among classical lab pets. A 🧵 1/13 #scicomm

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Alexander Harms

@AHarms485

4 months

This has been a difficult one... the whole household is cheering that the paper is finally published! 🥂

Alexander Harms

@AHarms485

4 months

Interested in how phages deal with dormant bacteria? After a looong and difficult peer review process Enea @phagemuffin presents the final version of our paper. 😁🔥👇🏼

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Alexander Harms

@AHarms485

2 years

Welcome to #PhageOfTheWeek ! We start with SuperGirl, a T5 relative of Epseptimavirus genus 🦸🏼‍♀️😎. SuperGirl is special for infecting E. coli K-12 and Salmonella Typhimurium lab strains equally well, likely due to lateral tail fibers matching the O-antigen of the latter. A 🧵1/5

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Alexander Harms

@AHarms485

6 months

New lab logo - created by magnificent scientist-artist Fabienne Estermann @fabi_est_ 😁🔥.

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Alexander Harms

@AHarms485

3 years

Great list (and so true 😆), but it lacks the current favorite in my bookmarks which is "We saw these two weird genes and had no clue what they do, so we checked if they are a phage defense system - and yes, they are."

Elisa Granato

@Prokaryota

3 years

Types of Microbiology paper. 🔬

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Alexander Harms

@AHarms485

2 years

I think we finally got blue / white selection with lytic phages to work also in our hands (lacZ alpha in phage genome, lacZ omega in host, X-gal in top agar)... 🔵🔵🔵🤩 This was clearly commonly used in the old days but somehow it took us a while to get the conditions right. 🤔

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Alexander Harms

@AHarms485

2 years

Totally agree! Sharing published material should be the norm and profits everyone. Over the last year we have basically every week sent phages, strains, or plasmids around the world to colleagues who needed them. Great feeling! 💌🧪🤝🏼

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Alexander Harms

@AHarms485

4 months

Well, that was easy - at least if the bacterial pathogen is not an obscure organism, we usually find lots of phages (here: uropathogenic E.coli). The more tricky next steps would be 1) to choose the right ones for therapy and 2) to effectively apply them to the patient... 🧬💉💊

Alexander Harms

@AHarms485

4 months

New year, new short-term intern - the task today: Using real clinical strains from 🇨🇭 that we never saw before, how difficult is it to find phages that could be used for therapy? 🧫🎣

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Alexander Harms

@AHarms485

6 months

Today I learned: The flagellar serotype "H" of enterobacteria stands for German "Hauch" ("breath") because swarming colonies on agar look like when you breathe at a glass slide... and the "O-antigen" was first seen with non-motile strains ("ohne Hauch"). I am stunned... 🤔🌬️🧫

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Alexander Harms

@AHarms485

2 years

#PhageOfTheWeek is back, this time with phage N4! This phage is a very peculiar podovirus that cares more about bacterial signaling than most microbiology students do – and it’s a tough fighter. A 🧵 (and sorry to the TEM aficionados for this grainy micrograph). 1/14

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Alexander Harms

@AHarms485

3 years

New preprint with our friends and colleagues of Urs Jenal's group @JenalLab including amazing @Prakapaite_R : Eschericia coli has a previously overlooked surface glycan that is the primary receptor of all phages formerly thought to target the enterobacterial common antigen (ECA).

bioRxiv Microbiology

@biorxiv_micrbio

3 years

A new sugar for an old phage: A c-di-GMP dependent polysaccharide pathway sensitizes E. coli for bacteriophage infection #biorxiv_micrbio

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Alexander Harms

@AHarms485

1 year

This is the end - last working day for our group at @biozentrum @UniBasel_en ! We handed over a clean + empty lab and had a last lunch with our friends of @JenalLab 🥲🤗🍾. Stay tuned for new phage adventures next year!

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Alexander Harms

@AHarms485

1 year

Big day! We celebrated the 20th anniversary of @MartinLoessner 's Lab of Food Microbiology at @ETH Zürich. Incidentally, it's also the first day of our own Lab of Molecular Phage Biology 😁🥂🎉. Looking forward to five great years as a strong community with Martin and his team!

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Alexander Harms

@AHarms485

2 years

All students using their labspace at the same time = say hello to the PI-in-the-lab bonus bench. 😁🛠️

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Alexander Harms

@AHarms485

2 years

Transmission electron microscopy with our high schoolers at the BioEM lab of @biozentrum @unibasel_en 🍿🔬. Each of them got their hands at the TEM to see their own phage 😁! The students' isolates included (left to right) T-even, T5-like, and Felix01-like phages 👇.

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Alexander Harms

@AHarms485

11 months

Sunset from the roof at ETH Zürich after a great symposium with all life sciences professors 🌇🌤️🧬

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Alexander Harms

@AHarms485

4 months

🚨 PhD position alert 🚨 Thilo Köhler and Christian van Delden at @unige_en @hug_ge offer a position on clinical phage therapy of Pseudomonas aeruginosa and its microbiological basis 🧫💉🦠. It is funded by @NCCR_AntiResist and will be in collaboration with us. 👇🏼

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Alexander Harms

@AHarms485

3 years

roses are red violets are blue the world belongs to microbes and the contaminant is you 😉❤️🦠 #AcademicValentine

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Alexander Harms

@AHarms485

2 years

We are training them young! #phagehunt 😁🧪🧫

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Alexander Harms

@AHarms485

1 year

Let's try something new today - a full day of paper writing on the train from Aarhus to Basel. Pray to the railway gods for an undisturbed and productive journey! 🚂🪄📚

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Alexander Harms

@AHarms485

2 years

You like TA systems and bacterial immunity but are too busy to read full articles? Aisylu @AisyluShaidull1 and I wrote a spotlight in @TrendsMicrobiol about the landmark paper by @michele__leroux + @michael_laub8 with @SorekLab on DarTG phage defense:

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Alexander Harms

@AHarms485

1 year

Deeply touched by a surprise dinner yesterday with all lab members and alumni to celebrate the (re)birth of our group. They composed a wonderful book about our history with touching entries from many friends and colleagues... I am speechless 🙏🏼❤️.

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Alexander Harms

@AHarms485

2 years

Basel phage hunters on the way back from @VoM_2022 - five amazing days full of science and meeting so many great people from all over the world! 😁☀️🧬🇵🇹

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Alexander Harms

@AHarms485

6 months

If it doesn't work out in academia I am going to start selling proper Currywurst in Switzerland. 🍟🌭😅

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Alexander Harms

@AHarms485

8 months

Some unlucky Drosophila landed on this soft agar plate, walked around with phages at its feet, and then died... I guess Pseudomonas aeruginosa killed it 🧫🦠🪰.

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Alexander Harms

@AHarms485

2 years

New favorite place for early morning office work at @BacNet22 ! 🌅

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Alexander Harms

@AHarms485

2 years

Exciting moments in the course lab of our Summer Science Academy - almost all of the twenty high schoolers got phages from their samples 😁🎣🧫. We will characterize them together for the rest of the two weeks 💪🏼🧪🧬. @biozentrum @UniBasel_en

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Alexander Harms

@AHarms485

9 months

Found when cleaning up a bench for a new student 🧬✂️... it's probably less than ten years old, but I guess most people in the lab today have no idea what this means. Crazy progress!

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Alexander Harms

@AHarms485

2 years

Today I am starting this significant document - looking forward towards an exciting journey and (if successful) my final academic grade at Basel University! 🧑‍🏫🧑‍🎓

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Alexander Harms

@AHarms485

2 years

Phage hunting with zoo animal feces was highly successful - we got so many of them that we had difficulties to select the scientifically most interesting ones! Here three nice examples (plates by Aisylu @AisyluShaidull1 ). 🐓🦁🐢

Alexander Harms

@AHarms485

2 years

Many thanks to @ZooBasel for supporting us at @biozentrum with fecal samples of their animals 😁💩🧪! Aisylu @AisyluShaidull1 and visiting PostDoc Toomas are already searching for new exciting phages for our research. #findingthemagicphage

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Alexander Harms

@AHarms485

2 years

New batch of mite cheese ("Würchwitzer Milbenkäse") arrived. One of my best ideas in recent times was to stalk the cheese mites using the smartphone microscope! 😍🕷️🔬

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Alexander Harms

@AHarms485

6 months

Fantastic preprint by our friends @NWenner and Anouk Bertola of @Diard_Lab on how phenotypic heterogeneity of the Salmonella O-antigen barrier affects resistance evolution to a T5-like phage, both in vitro and in vivo!👇🏽🧬🔥!

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Alexander Harms

@AHarms485

4 years

Newly isolated phages are always like Christmas and Easter on the same day - it is just amazing that each of these plaques contains a little piece of life that nobody has seen before! All credit for the wonderful plate goes to expert phage hunter Enea Maffei @phagemuffin .

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Alexander Harms

@AHarms485

3 years

I think autumn is the best season for food in Switzerland. 😁🧀🔥🇨🇭

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Alexander Harms

@AHarms485

8 months

Scientists of Twitter! The world needs more reminders that we're living, breathing human beings. Quote tweet this with a picture of you doing not-science.

Akos T. Kovacs

@EvolvedBiofilm

8 months

Scientists of Twitter! The world needs more reminders that we're living, breathing human beings. Quote tweet this with a picture of you doing not-science

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Alexander Harms

@AHarms485

2 years

#PhageOfTheWeek is back with phage P2! This virus does a rather bad job as a predator (those plaques! 😁), but that’s okay – as a temperate phage it doesn’t need active infections very often. Instead, it elegantly boosts lysogen fitness through bacterial immunity 🦠🛡️. A 🧵 1/15

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Alexander Harms

@AHarms485

2 years

After two years of pandemic we are back at teaching @biozentrum students at least mask-to-mask, though not yet face-to-face. But great relief for everybody to be back! 😷😁

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Alexander Harms

@AHarms485

2 years

Our two-week "summer science academy" with twenty high schoolers at @biozentrum @UniBasel_en ends today and was a great success 😁! But for the students' phages it will be a new beginning - they were of course not sampled randomly 😉🎣. Watch out for preprints later this year! 🔥

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Alexander Harms

@AHarms485

2 years

#PhageOfTheWeek is back with AugustePiccard / Bas01 (👇) representing a ubiquitous group of small phages with a big love for porins. This one had a secret love for LptD that it shares with the R&D departments of antibiotic pharma companies - more on that later 💊😉. A 🧵 1/18

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Alexander Harms

@AHarms485

2 years

#OnThisDay three years ago during a May Hike I found a huge pile of rotting plants behind Hörnli cemetery in Basel. Some smelly juice ended up in the lab where Enea @phagemuffin eventually isolated phage Paride from it - now a major focus in the group! 😁♻️🧪

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Alexander Harms

@AHarms485

1 year

"New faculty orientation days" of ETH Zürich teach us new professors from all fields how this organisation works 🎓🇨🇭. Great bonus: Stunning views over Lake Zürich and the mountains!

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Alexander Harms

@AHarms485

2 years

First time of the season! 😁🔥🌭🍻

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Alexander Harms

@AHarms485

4 months

How do we get new antibiotics that work in real life? In this article our @NCCR_AntiResist consortium argues that in vitro models mimicking relevant patient-like conditions will be a crucial tool to find the right molecules (or phages 😉). 🔥👇🏼

Nature Microbiology

@NatureMicrobiol

4 months

Out now! In vitro models that mimic within patient conditions should be used to revitalize antibiotic discovery and development

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Alexander Harms

@AHarms485

2 years

Yesterday scientist-artist Fabienne Estermann @fabi_est_ did some bacterial agar art with our high schoolers at @biozentrum @UniBasel_en ! 👩🏼‍🎨🎨🦠🧫 I admire their creativity and precision - they would make good scientists if they want 😁.

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Alexander Harms

@AHarms485

3 years

Phishing new phages never gets old - first time in the new lab. 😁🧫🎣 (direct isolation from river water on a usually difficult E. coli host - I guess abundance and diversity might be favored by all the materials carried in by current high water)

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Alexander Harms

@AHarms485

3 years

Today just out of a mood I asked our son if he is German, Swiss, or (like his beloved grandma) Greek. He evidently thought that's a stupid question and answered "Papa, I am Johann!" His mother and I count this as a parenting win 🌍☃️👍🏼.

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Alexander Harms

@AHarms485

8 months

Cool new phages selected by our summer interns hunting for novel biology 👇🏼🧫. Very exciting and a good moment to apply for more funding so we can understand how they do what they do 🕵️🔥!

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Alexander Harms

@AHarms485

3 years

Barbecue with umbrella, Swiss "summer" of 2021. 💨💦

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Alexander Harms

@AHarms485

4 years

Proud to work side by side with my amazing students Aisylu Shaidullina, Marco Burkolter @phageboi , and Enea Maffei @phagemuffin ! Best ideas, best discussions, and the most interesting phages 🤗👍. Stay tuned for their papers 😉. Photo by Annette Roulier of @biozentrum .

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Alexander Harms

@AHarms485

2 years

The "Phages in Paris" conference of @Phages_fr is coming to an end. For sure one of the best meetings I ever attended - top science, great people, excellent organization. And such a lively + beautiful city! 🧬🇫🇷😁

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Alexander Harms

@AHarms485

2 years

#PhageOfTheWeek is back with a little monster that started as a lab pet – temperate phage phi80, a cousin of phage lambda. We crossed paths when I was a PostDoc and then things escalated quickly, causing great relief for some people and significant grief for others. A 1/12

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Alexander Harms

@AHarms485

10 months

Relaxing breakfast in the middle of Tbilisi - ready to meet all of you at @vom2023 ☕🏙️🌳!

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Alexander Harms

@AHarms485

1 year

Great pleasure to hear Swiss phage therapy advocate Thomas Häusler @thaeusler yesterday at @biozentrum ! We still have some way to go in 🇨🇭 until phages are openly available to patients in need, but if we work together as a community we can make it happen.

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Alexander Harms

@AHarms485

1 year

This is insane! A phage RNA polymerase fused to the tape measure protein, possibly for immediate transcription after genome injection...

Maria SOKOLOVA

@arimiora28

1 year

1/7 Look at this P23-45 phage discovered by Konstantin Severinov many years ago () and prepare to be surprised!

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Alexander Harms

@AHarms485

11 months

Great retreat in the mountains with @MartinLoessner to discuss the strategy of our labs - stay tuned for the next level of phage research at ETH Zürich🏞️🧬🦠!

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Alexander Harms

@AHarms485

2 years

Basel phage hunters are ready for the Swiss Society for Microbiology congress - looking forward to meeting all of you who are with us in Lausanne! 🦠🧪🇨🇭