bioRxiv Microbiology @biorxiv_micrbio Twitter profile

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bioRxiv Microbiology

@biorxiv_micrbio

3 years

The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines #biorxiv_micrbio

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bioRxiv Microbiology

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4 years

Reinfection could not occur in SARS-CoV-2 infected rhesus macaques #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

4 years

Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

Mapping the landscape of anti-phage defense mechanisms in the E. coli pangenome #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

1 year

Mammalian cells internalize bacteriophages and utilize them as a food source to enhance cellular growth and survival #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

1 year

gcplyr: an R package for microbial growth curve data analysis #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

8 months

Asgard archaea defense systems and their roles in the origin of immunity in eukaryotes #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

Phage-plasmids spread antibiotic resistance genes through infection and lysogenic conversion #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 years

Rapid evolutionary turnover of mobile genetic elements drives microbial resistance to viruses #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 years

Plasmid fitness costs are caused by specific genetic conflicts #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

A sarbecovirus found in Russian bats uses human ACE2 #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

5 years

Selection of representative genomes for 24,706 bacterial and archaeal species clusters provide a complete genome-based taxonomy #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

4 years

Thousands of previously unknown phages discovered in whole-community human gut metagenomes #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

5 years

Isolation of an archaeon at the prokaryote-eukaryote interface #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

4 years

Comprehensive analysis of horizontal gene transfer among multidrug-resistant bacterial pathogens in a single hospital #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 years

The gut bacterial natural product colibactin triggers induction of latent viruses in diverse bacteria #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

A family of novel immune systems targets early infection of nucleus-forming jumbo phages #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 years

Stop codon recoding is widespread in diverse phage lineages and has the potential to regulate translation of late stage and lytic genes #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

4 years

Bacterial retrons function in anti-phage defense #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

Direct activation of an innate immune system in bacteria by a viral capsid protein #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

Phage-encoded sigma factors alter bacterial dormancy #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

The SARS-CoV-2 variant, Omicron, shows rapid replication in human primary nasal epithelial cultures and efficiently uses the ... #biorxiv_micrbio

The SARS-CoV-2 variant, Omicron, shows rapid replication in human primary nasal epithelial cultures...

At the end of 2021 a new SARS-CoV-2 variant, Omicron, emerged and quickly spread across the world. It has been demonstrated that Omicron’s high number of Spike mutations lead to partial immune...

www.biorxiv.org

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bioRxiv Microbiology

@biorxiv_micrbio

3 months

Phages reconstitute NAD+ to counter bacterial immunity #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

1 year

A new antibiotic from an uncultured bacterium binds to an immutable target #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

ResFinderFG v2.0: a database of antibiotic resistance genes obtained by functional metagenomics #biorxiv_micrbio

ResFinderFG v2.0: a database of antibiotic resistance genes obtained by functional metagenomics

Metagenomics can be used to monitor the spread of antibiotic resistance genes (ARGs). ARGs found in databases such as ResFinder and CARD primarily originate from culturable and pathogenic bacteria....

www.biorxiv.org

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bioRxiv Microbiology

@biorxiv_micrbio

1 year

A widespread bacterial mobile genetic element encodes weapons against phages, bacteria, and eukaryotes #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 years

A genomic perspective on genome size distribution across Earth's microbiomes reveals a tendency to gene loss #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

Identification and characterization of thousands of bacteriophage satellites across bacteria #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

Bows and swords: why bacteria carry short and long-range weapons #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

1 year

Diverse and Abundant Viruses Exploit Conjugative Plasmids #biorxiv_micrbio

Diverse and abundant viruses exploit conjugative plasmids

Viruses exert profound evolutionary pressure on bacteria by interacting with receptors on the cell surface to initiate infection. While the majority of bacterial viruses, phages, use chromosomally-...

www.biorxiv.org

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

Bacterial droplet-based single-cell RNA-seq reveals heterogeneity in bacterial populations and in response to antibiotic perturbation #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

4 years

Pseudomonas aeruginosa is capable of natural transformation in biofilms #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

4 years

Targeted Genome Editing of Bacteria Within Microbial Communities #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

9 months

Bacterial cGAS-like enzymes produce 2',3'-cGAMP to activate an ion channel that restricts phage replication #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

4 years

Identification of antiviral drug candidates against SARS-CoV-2 from FDA-approved drugs #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

4 years

A mouse-adapted SARS-CoV-2 model for the evaluation of COVID-19 medical countermeasures #biorxiv_micrbio

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bioRxiv Microbiology

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1 year

In Vitro Evolution to Increase the Titers of Difficult Bacteriophages: Rapid Appelmans Protocol #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 years

The SARS-CoV-2 variants associated with infections in India, B.1.617, show enhanced spike cleavage by furin #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

1 year

Restriction-modification systems have shaped the evolution and distribution of plasmids across bacteria #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 years

Prophages integrating into prophages: a mechanism to accumulate type III secretion effector genes and duplicate Shiga toxin-encoding ... #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

4 years

The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

Phages against non-capsulated Klebsiella pneumoniae: broader host range, slower resistance #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

Peptidoglycan maturation controls spatiotemporal organisation of outer membrane proteins in Escherichia coli #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 years

Resolving the structure of phage-bacteria interactions in the context of natural diversity #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

1 year

Bacterial defences interact synergistically by disrupting phage cooperation #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

4 years

Prophage-encoded phage defence proteins with cognate self-immunity #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

4 years

Phages weaponize their bacteria with biosynthetic gene clusters #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

The giant Mimivirus 1.2 Mb genome is elegantly organized into a 30 nm helical protein shield #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 years

Genome evolution in bacteria isolated from million-year-old subseafloor sediments #biorxiv_micrbio

Genome evolution in bacteria isolated from million-year-old subseafloor sediments

Deep below the seafloor, microbial life subsists in isolation from the surface world under perpetual energy limitation. The extent to which subsurface microbes evolve and adapt to their subseafloor...

www.biorxiv.org

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

Bacterial produce membrane-binding small molecules to regulate horizontal gene transfer in vesicles #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

5 years

Identifying transposon insertions in bacterial genomes through nanopore sequencing #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

8 years

Deep Annotation of Protein Function across Diverse Bacteria from Mutant Phenotypes #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

5 years

Assembly-free single-molecule nanopore sequencing recovers complete virus genomes from natural microbial communities #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

5 months

Predicting phage-bacteria interactions at the strain level from genomes #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 years

Comparative genomics reveals electron transfer and syntrophic mechanisms differentiating methanotrophic and methanogenic archaea #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 months

A new archaeal virus that suppresses the transcription of host immunity genes #biorxiv_micrbio

A new archaeal virus that suppresses the transcription of host immunity genes

In some extreme environments, archaeal cells have been shown to have chronic viral infections, and such infections are well-tolerated by the hosts and may potentially protect against more lethal...

www.biorxiv.org

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bioRxiv Microbiology

@biorxiv_micrbio

2 months

Prophages block cell surface receptors to ensure survival of their viral progeny #biorxiv_micrbio

Prophages block cell surface receptors to ensure survival of their viral progeny

In microbial communities, viruses compete for host cells to infect, and thus evolved diverse ways to inhibit their competitors. One mechanism is Superinfection exclusion (Sie), whereby a virus that...

www.biorxiv.org

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bioRxiv Microbiology

@biorxiv_micrbio

5 years

Metagenomic Nanopore sequencing of influenza virus direct from clinical respiratory samples #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 years

The B1.351 and P.1 variants extend SARS-CoV-2 host range to mice #biorxiv_micrbio

The B1.351 and P.1 variants extend SARS-CoV-2 host range to mice

Receptor recognition is a major determinant of viral host range, as well as infectivity and pathogenesis. Emergences have been associated with serendipitous events of adaptation upon encounters with...

www.biorxiv.org

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

Bacteriophage anti-defense genes that neutralize TIR and STING immune responses #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 months

Anti-viral defense by an ADP-ribosyltransferase that targets mRNA to block translation #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

Bacterial motility governs the evolution of antibiotic resistance in spatially heterogeneous environments #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 months

H-NS is a bacterial transposon capture protein #biorxiv_micrbio

H-NS is a bacterial transposon capture protein

The histone-like nucleoid structuring (H-NS) protein is a DNA binding factor, found in γ-proteobacteria, with functional equivalents in diverse microbes. Universally, such proteins are understood to...

www.biorxiv.org

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bioRxiv Microbiology

@biorxiv_micrbio

1 year

Defense systems are pervasive across chromosomally integrated mobile genetic elements and are inversely correlated to virulence and ... #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 months

Bacterium secretes chemical inhibitor that sensitizes competitor to bacteriophage infection #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

5 years

Global phylogeography and ancient evolution of the widespread human gut virus crAssphage #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

6 months

MicrobeMod: A computational toolkit for identifying prokaryotic methylation and restriction-modification with nanopore sequencing #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

5 years

The impact of DNA polymerase and number of rounds of amplification in PCR on 16S rRNA gene sequence data #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

Accumulation of defense systems drives panphage resistance in Pseudomonas aeruginosa #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 years

Antiviral defense via nucleotide depletion in bacteria #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

4 years

Combining antibiotics with antivirulence compounds is effective and can reverse selection for antibiotic resistance in Pseudomonas ... #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

9 months

Toxinome - The Bacterial Protein Toxin Database #biorxiv_micrbio

Toxinome - The Bacterial Protein Toxin Database

Protein toxins are key molecular weapons in biology that are used to attack neighboring cells. Bacteria use protein toxins to kill or inhibit growth of prokaryotic and eukaryotic cells using various...

www.biorxiv.org

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bioRxiv Microbiology

@biorxiv_micrbio

6 years

E. coli translation strategies differ across nutrient conditions #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

5 years

Prophage induction mediated by quorum sensing signals alters soil bacterial community structure #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

4 years

FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in bacterial cell division #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 years

Zoonotic potential of a novel bat morbillivirus #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

7 months

The impact of phage and phage resistance on microbial community dynamics #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 years

Phage infection restores PQS signaling and enhances growth of a Pseudomonas aeruginosa lasI quorum-sensing mutant #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

1 year

Mycobacteria form viable cell wall-deficient cells that are undetectable by conventional diagnostics #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

Close relatives of MERS-CoV in bats use ACE2 as their functional receptors #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

4 years

Matrix-trapped viruses can protect bacterial biofilms from invasion by colonizing cells #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

5 years

Over 50000 metagenomically assembled draft genomes for the human oral microbiome reveal new taxa #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

4 years

Improved inference and prediction of bacterial genotype-phenotype associations using pangenome-spanning regressions #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

1 year

The antiphage defense system CBASS controls resistance and enables killing by antifolate antibiotics in Vibrio cholerae #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

Bacterial NLR-related proteins protect against phage #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

An ecological perspective on microbial genes of unknown function in soil #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 years

Highly efficient SARS-CoV-2 infection of human cardiomyocytes: spike protein-mediated cell fusion and its inhibition #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

cGASylation by a bacterial E1-E2 fusion protein primes antiviral immune signaling #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

8 months

Bacteria conjugate ubiquitin-like proteins to interfere with phage assembly #biorxiv_micrbio

Bacteria conjugate ubiquitin-like proteins to interfere with phage assembly

Multiple immune pathways in humans conjugate ubiquitin-like proteins to virus and host molecules as a means of antiviral defense. Here we studied an anti-phage defense system in bacteria, comprising...

www.biorxiv.org

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bioRxiv Microbiology

@biorxiv_micrbio

6 years

Experimental Evolution of Cell Shape in Bacteria #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

10 days

A phage satellite manipulates the viral DNA packaging motor to inhibit phage and promote satellite spread #biorxiv_micrbio

A phage satellite manipulates the viral DNA packaging motor to inhibit phage and promote satellite...

ICP1, a lytic bacteriophage of Vibrio cholerae , is parasitized by phage satellites, PLEs, which hijack ICP1 proteins for their own horizontal spread. PLEs’ dependence on ICP1’s DNA replication...

www.biorxiv.org

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bioRxiv Microbiology

@biorxiv_micrbio

3 years

CRISPR-Cas systems are widespread accessory elements across bacterial and archaeal plasmids #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

4 months

CRISPR-repressed toxin-antitoxin provides population-level immunity against diverse anti-CRISPR elements #biorxiv_micrbio

CRISPR-repressed toxin-antitoxin provides population-level immunity against diverse anti-CRISPR...

Prokaryotic CRISPR-Cas systems are highly vulnerable to phage-encoded anti-CRISPR (Acr) factors. How CRISPR-Cas systems protect themselves remains unclear. Here, we uncovered a broad-spectrum...

www.biorxiv.org

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bioRxiv Microbiology

@biorxiv_micrbio

2 years

A fungal secondary metabolism gene cluster enables mutualist-pathogen transition in root endophyte Colletotrichum tofieldiae #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 years

A Broadly Conserved Deoxycytidine Deaminase Protects Bacteria from Phage Infection #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

3 years

Bacterial gasdermins reveal an ancient mechanism of cell death #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

4 years

Rapid adaptation of SARS-CoV-2 in BALB/c mice: Novel mouse model for vaccine efficacy #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

17 days

Systematic Discovery of Phage Genes that Inactivate Bacterial Immune Systems #biorxiv_micrbio

Systematic Discovery of Phage Genes that Inactivate Bacterial Immune Systems

Bacteria have developed numerous defense systems to counter phage infections. However, the extent to which phages possess countermeasures against these defense systems remains unclear. In this study,...

www.biorxiv.org

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bioRxiv Microbiology

@biorxiv_micrbio

4 years

Horizontal gene transfer drives the evolution of dependencies in bacteria #biorxiv_micrbio

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bioRxiv Microbiology

@biorxiv_micrbio

4 years

Genome-wide Functional Characterization of Escherichia coli Promoters and Regulatory Elements Responsible for their Function. #biorxiv_micrbio

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