Nature Microbiology - Using agar media suspended in pipette tips and a standard camera, the geometric viability assay provides a user-friendly and scalable update to standard...

Nature - After 600 rounds of selection, anaerobic snowflake yeast evolved to be macroscopic, becoming around 20,000 times larger (approximately mm scale) and about 10,000-fold more biophysically...

Nature - Variations in microbial composition, phage induction, antimicrobial resistance genes and bile acid profiles are identified by using an ingestible device for site-specific sampling along...

Nature - The tail fibre of an extracellular contractile injection system (eCIS) from Photorhabdus asymbiotica recognizes targets expressed on eukaryotic host cells, and can be reprogrammed to...

Nature Microbiology - Staphylococcus epidermidis IVK83, a nasal commensal, produces an extremely short-lived, broad-spectrum antimicrobial peptide–polyene called epifadin, which eliminates...

Nature Microbiology - This Resource combines amplicon sequencing, shotgun metagenomic sequencing and untargeted metabolomics to provide a global view of microbial–metabolite associations...

Nature Microbiology - Residual human DNA reads in sequenced faecal samples may allow some individuals to be identified.

Nature Microbiology - Three distinct families of gut bacteria encode an unprecedented number of respiratory-like reductases per genome to perform anaerobic respiration of biomedically relevant...

Nature Microbiology - The cryogenic electron microscopy structure of the Pseudomonas aeruginosa cell division complex and antibiotic drug target, FtsWIQBL, suggests a possible activation mechanism.

Nature Microbiology - microbeMASST is a tool to associate known and unknown metabolites to microbial producers leveraging untargeted metabolomics data.

Nature Microbiology - In this Consensus Statement, the authors discuss the issue of naming uncultivated prokaryotic microorganisms, which currently do not have a formal nomenclature system due to a...

Nature Microbiology - HecRE is identified as a molecular switch regulating cyclic di-GMP levels and promoting binary cell states during Pseudomonas aeruginosa surface colonization and biofilm...

Nature Microbiology - High-throughput bacterial transcriptomics of 409 drug–microorganism interactions reveals mechanistic insights into drug-mediated microbiota shifts.

Microbial communities sourced from more extreme climates can help tree seedlings tolerate cold and drought.

Itch evokes a desire to scratch, but the link between microbes and itch was unclear. Staphylococcus aureus, a bacterial pathogen, secretes a protease V8 that activates PAR1 expressed on neurons to...

Nature Microbiology - Fetal meconium does not have a detectable microbiota, as shown using 16S rRNA sequencing and culture of rectal swabs collected during elective breech caesarean sections...

Nature Microbiology - Walker and Hoyles highlight selected myths and misconceptions in the human microbiota literature.

Nature Microbiology - The authors characterize two phages against Acinetobacter baumannii, both in vitro and in vivo. A. baumannii strains develop resistance against both phages, but are in turn...

Nature - A study demonstrates that specific interactions between the two committed enzymes for the synthesis of lipopolysaccharide and peptidoglycan enable coordinated assembly of the outer...

Nature Microbiology - The Omicron variant evades vaccine-induced neutralization but also fails to form syncytia, shows reduced replication in human lung cells and preferentially uses a...

Nature Microbiology - Quantitative metagenomic analyses of gut microbiomes reveals kinship, together with current cohabitation, as drivers of microbial community transmission and persistence...

Nature Microbiology - CRISPR spacers in DPANN archaea target putative essential genes in their episymbionts and could be a widespread occurrence across diverse archaeal lineages.

Nature Microbiology - Recovery of 1,167 nonredundant archaeal genomes from the human gut microbiomes reveals previously undescribed genera, associations with sociodemographic factors and the...

Nature Microbiology - Cryo-electron tomography reveals unanticipated features of Bdellovibro predation of Gram-negative bacteria.

Nature Microbiology - In vitro models mimicking in-patient conditions have the potential to yield exciting opportunities for antibiotic research and revitalize future antibiotic discovery and...

Nature - A study reports the development of a structural derivative of amphotericin B with broad antifungal activity in mice but without the renal toxicity associated with amphotericin B.

Associate or Senior Editor, Nature Microbiology

Nature Reviews Microbiology - In this Review, Tan and colleagues highlight recent efforts to discover non-traditional antimicrobials and explore the therapeutic potential of antimicrobial peptides...

Nature Microbiology - Computational analyses reveal widespread recoding in gut phages, which is hypothesized to control timing of lysis.

Nature Microbiology - Biochemical characterization of glycogen-degrading enzymes in vaginal bacteria reveals that the vaginal microbiota possesses the ability to metabolize glycogen in this...

Nature Microbiology - An outline of best practices, resources and suggested improvements to ensure that the complexities inherent to microbial big data do not hamper accessibility.

Nature Microbiology - A model to predict bacterial community assembly is devised on the basis of experimental data reporting competition for resources in vitro.

Nature Microbiology - Carbon catabolism of heterotrophic bacteria can be described using a simple general principle, which is their preference for either glycolytic (sugars) or gluconeogenic (amino...

Nature Communications - Bacterial nanotubes and other similar membranous structures have been reported to function as conduits between cells to exchange DNA, proteins, and nutrients. Here the...

Nature Microbiology - Transposon mutagenesis identifies Akkermansia muciniphila genes required for growth on mucin and colonization of the intestinal tract.

Nature Microbiology - An analysis of over 2,000 genomes from Human Microbiome Project metagenomic data led to the identification of several extended- and narrow-spectrum antibiotics against...

Nature Microbiology - Ocean viral proteome annotations are expanded by a machine learning approach that is not reliant on sequence homology and can annotate sequences not homologous to those seen...

Microorganisms are potential enablers of a more sustainable and healthy food system. This perspective reviews current approaches and discusses future advances in science-driven fermentation, synthe...

Nature Microbiology - The Bacteroides fragilis ubiquitin homologue, BfUbb, mediates intraspecies competition and provides a competitive advantage for encoding strains in the gut.

Nature Microbiology - Depletion of the deoxynucleotide pool by a family of dCTP deaminases, and a family of dGTPases, defends bacteria against phage infection.

Nature Microbiology - While deaths from leading infectious diseases have decreased since the millennium, the threat from potential new outbreaks means that complacency is not an option. The global...

Nature Microbiology - In Pyrococcus furiosus, histones bind and bend DNA to enable integration of new spacer fragments into CRISPR loci.

Bacteria can be engineered to detect human DNA with specific mutations, including ones associated with tumors.

Nature Microbiology - Pan-genome analyses of clinical pneumococcal strains identify categories of essential genes and show that gene essentiality depends on strain genetic background.

Long thought to be a defense system unique to the bloodstream, complement is shown here to be synthesized locally in the mammalian intestine, where it helps tune the tolerance to the gut microbiota...

Nature Biotechnology - Challenges and opportunities for engineering and studying the soil microbiome are discussed.

Nature Microbiology - The fungal genus Armillaria includes virulent necrotrophic pathogens, unusual wood decayers and the largest terrestrial organisms on Earth. Sahu et al. suggest that horizontal...

A type of oil-eating bacteria adapts its biofilm interfacial properties to accelerate the rate of oil consumption.

Nature - We use a whole-cell accumulation assay to assess the ability of non-antibiotic, structurally diverse small molecules to accumulate in Pseudomonas aeruginosa, with potential application in...

Nature - The authors use a machine-learning approach to uncover confounding variables in studies that seek to establish an association between the gut microbiota and human disease.

Nature - Jessica Sacher works to develop tools for phage therapy, with the aim of overcoming antimicrobial resistance.