Kevin Mitchell @WiringTheBrain Twitter profile

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Kevin Mitchell

@WiringTheBrain

1 year

"Free Agents - How Evolution Gave Us Free Will" will be out on October 3rd, from @PrincetonUPress 😊

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Kevin Mitchell

@WiringTheBrain

7 years

New rule: news stories on vaccination should use a picture of someone with the awful disease, as opposed to a big-ass needle #vaccineswork

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Kevin Mitchell

@WiringTheBrain

11 months

Bertrand Russell's response to fascist Oswald Mosley's entreaties to debate him:

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Kevin Mitchell

@WiringTheBrain

4 years

This lockdown is getting pretty competitive. Did you record an amazing multi-part song with your family like the von Trapps? Did you bake sourdough from cultures rescued from the Egyptian pyramids? Did you film a stop-motion Lego movie with your 3-year-old? No. No you didn't.

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Kevin Mitchell

@WiringTheBrain

5 years

Darwin, on cultivating the habits to combat his own confirmation bias:

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Kevin Mitchell

@WiringTheBrain

3 years

Gall’s Law: All complex systems that work evolved from simpler systems that worked. A complex system designed from scratch never works, and cannot be patched up to make it work. You have to start over, beginning with a simple system.

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Kevin Mitchell

@WiringTheBrain

1 year

PSA: Dopamine is not a reward molecule. That is all.

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Kevin Mitchell

@WiringTheBrain

6 years

A little reminder that to get from genotypes to phenotypes, you have to go through development...

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Kevin Mitchell

@WiringTheBrain

7 months

@StuartJRitchie This is one of those things where people assume their subjective experience is the same as everyone else’s. It isn’t.

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Kevin Mitchell

@WiringTheBrain

5 years

New study finds fecal transplants from concert pianists improve discrimination of musical tones in mice.

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Kevin Mitchell

@WiringTheBrain

1 year

@AdamRutherford Hmm... should I offer a firm handshake with a veiled threat of violence or pat you on the bottom? So hard to know... So confusing for me...

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Kevin Mitchell

@WiringTheBrain

4 years

Geneticist version: No. No. No, that's not what heritability means No. Yes, complex traits are complex No. CRISPR won't fix everything No. Epigenetics doesn't mean what you think it means No. Yes, Darwin is still right

Dr. Heather Ratigan

@hcratigan

4 years

Neuroscientist version: No. No. No, you do use all 100% of your brain, both sides of it too No. Yes, consciousness is a complicated problem No. Elon Musk won't fix everything No. AI doesn't work like your brain does No. Yes, dendrites are pretty

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Kevin Mitchell

@WiringTheBrain

5 years

For the love of Christ - just read them the fucking story already. It's nice. You can have a snuggle. It makes them go to sleep. Their brains will take care of themselves...

Big Think

@bigthink

5 years

How to maximize the brain benefits of storytime for infants

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Kevin Mitchell

@WiringTheBrain

5 years

Neurosexism: the myth that men and women have different brains - this battle of extreme positions obscures the more nuanced and realistic position of an interplay between biology and culture

Neurosexism: the myth that men and women have different brains

Nature - The hunt for male and female distinctions inside the skull is a lesson in bad research practice, writes Lise Eliot.

www.nature.com

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Kevin Mitchell

@WiringTheBrain

2 years

Amazing how much information our minds "fill in" for this image, especially if you scroll past it fast

Akiyoshi Kitaoka

@AkiyoshiKitaoka

2 years

音声かな？

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Kevin Mitchell

@WiringTheBrain

1 year

Some holiday reading (and re-reading) in preparation for our new module on Systems - the Science of Everything 😊

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Kevin Mitchell

@WiringTheBrain

5 years

Once again, for the racists in the back... The observed difference in IQ b/w Irish + English in 1970s was thought by many, like Eysenck, to be (obviously) genetic in origin. That gap has since disappeared, with changes in environment...

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Kevin Mitchell

@WiringTheBrain

3 years

Look how absolutely jam-packed with proteins the cell is! (in this case the postsynaptic spine)

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Kevin Mitchell

@WiringTheBrain

6 years

Thrilled to share the cover for my new book, INNATE - How the Wiring of Our Brains Shapes Who We Are. @PrincetonUPress

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Kevin Mitchell

@WiringTheBrain

6 years

Since a couple people have asked my opinion, this is where I think the science stands on sex differences in psychological traits + what the implications are:

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Kevin Mitchell

@WiringTheBrain

5 years

This is just not the case. Males really are more aggressive and violent than females, in humans as in most other mammals, for good evolutionary reasons, due to mechanisms that are getting to be well worked out

Psychology Today

@PsychToday

5 years

"It's not their hormones that make men more violent, it's their socialization"

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Kevin Mitchell

@WiringTheBrain

4 years

No. Just stop.

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Kevin Mitchell

@WiringTheBrain

4 years

Irish-developed kit confirms coronavirus infection in 15 minutes - great work by two of our @tcddublin Genetics alumni, @MacFhearraigh + @TheRealColmRyan ! 👏

Irish-developed kit confirms infection in 15 minutes

An Irish company is preparing to release rapid Covid-19 testing kits, which can provide results in 15 minutes and potentially act as a "clinical weapon" ag...

www.independent.ie

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Kevin Mitchell

@WiringTheBrain

7 months

The molecular and mathematical basis of Waddington's epigenetic landscape: a framework for post-Darwinian biology? - this (2012) paper gives a great dynamical systems view of gene regulatory networks

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Kevin Mitchell

@WiringTheBrain

4 years

These studies really DON'T show that reading to kids changes their brains (or that screen time affects them either)... thread follows

CNN

@CNN

4 years

Scans of preschoolers' brains show a stark difference in brain development when read to by a parent as compared to when they are playing on screens alone, studies show.

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Kevin Mitchell

@WiringTheBrain

2 years

PSA: genetics as a science is not about genes causing traits. It's about how *variation* in genes causes *variation* in traits.

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Kevin Mitchell

@WiringTheBrain

5 years

It’s Dangerous to Be a Boy - astonishing level of nonsense in here, with a simply unsupported claim that sex differences in aggression have no innate basis

Opinion | It’s Dangerous to Be a Boy (Published 2019)

They smoke more, fight more and are far more likely to die young than girls. But their tendency to violence isn’t innate.

www.nytimes.com

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Kevin Mitchell

@WiringTheBrain

8 years

For transgenerational epigenetic transmission of behaviour to occur in mammals, here's what would have to happen:

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Kevin Mitchell

@WiringTheBrain

11 months

A little rant: I’ve noticed a trend in some science communication, especially in discussions about neuroscience and psychology research, and I don’t like it…

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Kevin Mitchell

@WiringTheBrain

3 years

The hungry brain! 🧠 Neocortex saves energy by reducing coding precision during food scarcity

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Kevin Mitchell

@WiringTheBrain

3 years

When we have finally associated every gene in the genome with some disease (or multiple diseases) we will finally realise: having genes is bad for your health

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Kevin Mitchell

@WiringTheBrain

4 years

This is an astonishing level of sophisticated cognition (never mind the dexterity!). Good boi!

Jay Arnold

@jayfarnold

4 years

Two can play at this game🐾💕

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Kevin Mitchell

@WiringTheBrain

2 years

Autism-related dietary preferences mediate autism-gut microbiome associations - important study refuting naive idea that gut microbiome somehow causes autism - arrow of causation goes the other way

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Kevin Mitchell

@WiringTheBrain

4 years

A wonderfully direct illustration of the fact that the genome encodes developmental rules, not precise outcomes

TLecuitLab

@LecuitLab

4 years

Check our new paper revealing self-organising properties of dendritic neuron morphogenesis. Wonderful collaboration between Amrutha @a_palavalli and Jean-François Rupprecht and Nicolas Tizon at @centuri_ls .

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Kevin Mitchell

@WiringTheBrain

2 years

This reveals such deep naivete about "the brain"... Where does the *meaning* of a pattern of neural activity come from? Where does it inhere? [Hint: not in the pattern]

Pop Crave

@PopCrave

2 years

Elon Musk’s brain-machine interface company Neuralink is currently looking for their clinical trial director to start testing brain chip on humans. “You will be able to save and replay memories. You could potentially download them into a new body or into a robot body.”

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Kevin Mitchell

@WiringTheBrain

5 years

Wait for it...

Daniel🎗🏴󠁧󠁢󠁷󠁬󠁳󠁿 ॐ

@DannyDutch

5 years

This hurt my tiny little brain.

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Kevin Mitchell

@WiringTheBrain

5 years

N=15 patients with autism spectrum disorder. Fifteen. One-five. And how many data points are trawled through to find some differences? <checks details for precise figure>... a gazillion.

Moheb Costandi

@mocost

5 years

Single-cell genomics identifies cell type–specific molecular changes in autism

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Kevin Mitchell

@WiringTheBrain

5 years

The magical thinking of guys who love logic via @outline - nails it!

The magical thinking of guys who love logic

Why so many men online love to use “logic” to win an argument, and then disappear before they can find out they're wrong.

theoutline.com

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Kevin Mitchell

@WiringTheBrain

5 years

God - please, make it stop! I can't even with this shit anymore...

Ajit Johnson Nirmal

@ajitjohnson_n

5 years

A new study identified that the microbiome modulates schizophrenia, typically thought of as a brain disease. Researchers gave mice fecal transplants from schizophrenic patients and watched the rodents' behavior take on similar traits. Hope for new drugs.

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Kevin Mitchell

@WiringTheBrain

2 years

Writing a book sure involves reading a lot of books! 📚

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Kevin Mitchell

@WiringTheBrain

1 year

Delighted to share the cover for my new book Free Agents! 😊 (It does exactly what it says on the tin 😉)

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Kevin Mitchell

@WiringTheBrain

4 years

You cannot test a hypothesis on the same data that suggested it. That is all.

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Kevin Mitchell

@WiringTheBrain

3 years

Anyone else have to cover their schoolbooks in wallpaper when they were young? 😅 WTF was that about?

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Kevin Mitchell

@WiringTheBrain

4 years

Really delighted to say that #Innate is now available in paperback! 😊

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Kevin Mitchell

@WiringTheBrain

5 years

If you choose to work long hours in science because you love spending your time that way and it's not really "work" to you, then great. But when the culture expects it and competition demands it, it can become toxic and unsustainable.

eLife - the journal

@eLife

5 years

Following a career in science involves long hours and hard work, but as Eve Marder explained in the first of the Living Science series, it can also be extremely rewarding

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Kevin Mitchell

@WiringTheBrain

4 years

This is mesmerising. It's not just a machine working away - those patterns *mean things*

Zebrafish Rock!

@ZebrafishRock

4 years

Neurons firing inside a #zebrafish brain. Credit to Philipp Keller @HHMIJanelia . #ZebrafishZunday

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Kevin Mitchell

@WiringTheBrain

8 months

How the strange idea of ‘statistical significance’ was born

A mathematical ritual known as null hypothesis significance testing has led researchers astray since the 1950s.

www.sciencenews.org

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Kevin Mitchell

@WiringTheBrain

7 years

Some of the books I have found useful in thinking about the higher-order principles that govern living systems... Suggestions welcome!

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Kevin Mitchell

@WiringTheBrain

26 days

We still doing growth mindset? Despite all the evidence that the supposed interventions have no effect?

Andrew D. Huberman, Ph.D.

@hubermanlab

26 days

New Huberman Lab podcast out now: MASTERING GROWTH MINDSET• •Beliefs About Effort Shape Outcome •Make Stress Performance Enhancing •Advice for Teachers & Students •Adolescence Shapes Work Ethic •Neuroplasticity & Growth Mindset •Implementation

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Kevin Mitchell

@WiringTheBrain

2 years

Well, now! Nature over Nurture: Functional neuronal circuits emerge in the absence of developmental activity

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Kevin Mitchell

@WiringTheBrain

4 years

Can we just agree to stop "pinpointing" brain regions that "drive consciousness"? Cuz that is some bullshit...

Big Think

@bigthink

4 years

Scientists pinpoint a tiny brain region that drives consciousness. The forebrain's central lateral thalamus seems to be one of the "minimum mechanisms" necessary for consciousness:

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Kevin Mitchell

@WiringTheBrain

5 years

If I'm descended from my grandfather, why are my cousins alive?

Steve Stewart-Williams

@SteveStuWill

5 years

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Kevin Mitchell

@WiringTheBrain

5 years

Argh! This is close but makes an important (and widespread) misinterpretation - that whatever variation cannot be ascribed to genetics must be due to the environment. This overlooks a hugely important source of individual differences: inherent variability of brain development

The Economist

@TheEconomist

5 years

Decades of research shows that human personality traits are a combination of genes and the environment. A new study confirms this is also the case for sexuality

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Kevin Mitchell

@WiringTheBrain

2 years

I see lots of great papers coming out analysing the functions of specific brain areas (sometimes several at a time) in behavioral control, using all the amazing tools now to hand in rodents... 1/n

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Kevin Mitchell

@WiringTheBrain

5 years

O autism-is-caused-by-the-microbiome study! How shall I nope thee? Let me count the ways...

Guardian Science

@guardianscience

5 years

Autism symptoms replicated in mice after faecal transplants

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Kevin Mitchell

@WiringTheBrain

6 months

Looking forward to debating Robert Sapolsky tomorrow (with @tedynenu moderating) on whether Free Will exists! (thanks to @wjsullivan for the pic 😊)

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Kevin Mitchell

@WiringTheBrain

3 years

Telling good science from bad – a user’s guide to navigating the scientific literature

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Kevin Mitchell

@WiringTheBrain

7 years

Wow. This is super just not true at all. The existence of rare exceptions does not invalidate the categories of male and female.

Scientific American

@sciam

7 years

To varying extents, many of us are biological hybrids on a male-female continuum.

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Kevin Mitchell

@WiringTheBrain

5 years

I just love this photograph! The absolute, undiluted joy of seeing something utterly profound that no one else has ever seen before...

MIT CSAIL

@MIT_CSAIL

5 years

Here's the moment when the first black hole image was processed, from the eyes of researcher Katie Bouman. #EHTBlackHole #BlackHoleDay #BlackHole (v/ @dfbarajas )

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Kevin Mitchell

@WiringTheBrain

24 days

What is supposed to follow from this?

Physics In History

@PhysInHistory

26 days

Not a single one of the cells that compose you knows who you are, or cares. - Daniel Dennett

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Kevin Mitchell

@WiringTheBrain

9 months

‘The Body Keeps the Score’ offers uncertain science in the name of self-help. It’s not alone. - The Washington Post - a terrific critique of neuro-self-help bullshit

Review | ‘The Body Keeps the Score’ offers uncertain science in the name of self-help. It’s not...

Some best-selling books express great confidence in theories of the brain that are still in their infancy.

www.washingtonpost.com

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Kevin Mitchell

@WiringTheBrain

3 years

The mouse cortico–basal ganglia–thalamic network - awesome work delineating the multiple parallel pathways through this action selection network 🐭🧠

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Kevin Mitchell

@WiringTheBrain

5 years

Each "part" of the brain is involved in many things, in different ways at different times, never alone but in shifting coalitions with different other "parts". Like genes, their functions cannot be separated.

Simon Eickhoff

@INM7_ISN

5 years

The brain is topographically organized but how to answer the question: "What does this part of the brain do?" This conceptual paper led by Sarah Genon is a great overview on how to attribute function to brain regions - and how to actually define function

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Kevin Mitchell

@WiringTheBrain

5 years

Perspectives are like accents. You don't realise you have one until you hear someone else's.

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Kevin Mitchell

@WiringTheBrain

3 years

This book is brilliant. Incredibly precise exposition of how reasons - grounded in beliefs, desires, and knowledge - drive behavior

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Kevin Mitchell

@WiringTheBrain

5 months

A lot of people ask me about my daily routine for neuro-optimising well-being and productivity* *Narrator: no had in fact asked… So here goes:

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Kevin Mitchell

@WiringTheBrain

2 years

Things are awful right now, but I am happy to say I've just submitted the manuscript for my new book, AGENTS to @PrincetonUPress 😊

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Kevin Mitchell

@WiringTheBrain

5 years

There's a famous quote with the idea that a person can remain an empiricist (believer in nurture) if they have only one child, but once they have a second they become a nativist (believer in nature). Anyone know source?

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Kevin Mitchell

@WiringTheBrain

5 years

@Don_lyall @DrRichJohnston PhD...

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Kevin Mitchell

@WiringTheBrain

6 years

Writing a blogpost about the evidence for transgenerational epigenetic inheritance in humans and I have to say, when you really dive into the data... there is none.

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Kevin Mitchell

@WiringTheBrain

3 years

Is the staggeringly profitable business of scientific publishing bad for science? - an eye-opening read!

Is the staggeringly profitable business of scientific publishing bad for science?

The long read: It is an industry like no other, with profit margins to rival Google – and it was created by one of Britain’s most notorious tycoons: Robert Maxwell

www.theguardian.com

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Kevin Mitchell

@WiringTheBrain

5 years

Advisory: this paper does NOT provide convincing evidence of this link (most of the work in mice, data from humans not compelling at all). Moreover, it was carried out by a company which aims to sell blockers of these toxins as a drug for AD

New Scientist

@newscientist

5 years

The key to treating Alzheimer's could be to block the toxins produced by Porphyromonas gingivalis, the main bacteria in chronic gum disease.

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Kevin Mitchell

@WiringTheBrain

7 years

Another favorite illusion to illustrate top-down influences on perception... (go ahead, measure 'em, I'll wait)

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Kevin Mitchell

@WiringTheBrain

3 years

Kathryn Paige Harden: ‘Studies have found genetic variants that correlate with going further in school’ - tricky stuff here...

Kathryn Paige Harden: ‘Studies have found genetic variants that correlate with going further in...

The behaviour geneticist explains how biology could have an influence on academic attainment – and why she takes an anti-eugenics approach

www.theguardian.com

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Kevin Mitchell

@WiringTheBrain

4 years

First Squid MRI Study Shows Brain Complexity Similar to Dogs via @inversedotcom

First squid MRI study shows brain complexity similar to dogs

Researchers put a squid in an MRI to study its neural networks. The resulting snapshots are stunning.

www.inverse.com

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Kevin Mitchell

@WiringTheBrain

4 years

How much innate knowledge can the genome encode? - my latest blogpost #AI #priors

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Kevin Mitchell

@WiringTheBrain

2 years

How the Krebs cycle powers life and death – fantastic talk by Nick Lane about the origins of metabolism and life - if only biochemistry had been taught like this when I was in college! 👏👍

How the Krebs cycle powers life and death – with Nick Lane

What process animates cells and gives life to lifeless matter? What brings our own lives to an end? The Krebs cycle is the answer - and it could turn our pic...

www.youtube.com

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Kevin Mitchell

@WiringTheBrain

2 years

New Study Disavows Marshmallow Test's Predictive Powers - another piece of social psychology "lore" falls... (from 2021)

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Kevin Mitchell

@WiringTheBrain

3 years

Finally got my birthday present framed and on the wall! 😊 @GDunnArt

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Kevin Mitchell

@WiringTheBrain

4 years

What do you mean "in broad daylight"? He's a pope, not a vampire...

Chico Harlan

@chicoharlan

4 years

Photo for surreal times: Pope Francis in broad daylight yesterday walking down one of Rome’s main shopping avenues. Barely anybody else was out on the streets.

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Kevin Mitchell

@WiringTheBrain

2 years

Re-upping this fantastic blog describing the salutary tale of research on the serotonin transporter gene - 5-HTTLPR: A Pointed Review

5-HTTLPR: A Pointed Review

In 1996, some researchers discovered that depressed people often had an unusual version of the serotonin transporter gene 5-HTTLPR. The study became a psychiatric sensation, getting thousands of ci…

slatestarcodex.com

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Kevin Mitchell

@WiringTheBrain

1 year

Very large twin study confirms high heritability of most brain structural imaging measures, neurocognitive traits, child psychopathology...

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Kevin Mitchell

@WiringTheBrain

5 years

Why is pharma abandoning neurological and psychiatric diseases? Because their shots in the dark have all missed. Strong evidence that more investment in basic neuroscience is what's needed...

John Carroll

@JohnCendpts

5 years

Another one bites the dust: Amgen is joining the biopharma exodus out of neurosciences R&D $AMGN $BIIB

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Kevin Mitchell

@WiringTheBrain

6 months

Robert Sapolsky vs Kevin Mitchell: The Biology of Free Will - this was a very fun debate - will be interested to hear people's reactions! Thanks to @tedynenu

Robert Sapolsky vs Kevin Mitchell: The Biology of Free Will |...

Professor Robert Sapolsky is a Professor of Biology, Neurology, and Surgery at Stanford University. He is the author of multiple books, including A Primate’s...

www.youtube.com

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Kevin Mitchell

@WiringTheBrain

2 years

😂 I literally LOLled!

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Kevin Mitchell

@WiringTheBrain

4 years

Looking forward to this online debate on sex differences; on @intelligence2 (Wed 6th May 6pm): 'There's No Such Thing As The Female Brain' @DaphnaJoel + @ginarippon1 will argue for the motion. @StuartJRitchie + @WiringTheBrain will argue against.

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Kevin Mitchell

@WiringTheBrain

5 years

Wow. This is weaponised neurobollocks, with added AI surveillance state creepiness... #blackmirror cc @Abebab

The Wall Street Journal

@WSJ

5 years

Some classrooms in China are equipped with AI cameras and brain-wave trackers. While many parents and teachers see them as tools to improve grades, they’ve become some children’s worst nightmare. #WSJWhatsNow

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Kevin Mitchell

@WiringTheBrain

2 years

Philosophy: turning unknown unknowns into known unknowns Science: turning known unknowns into, like, provisionally accepted knowns, for now, but, like, totally stay tuned...

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Kevin Mitchell

@WiringTheBrain

2 years

What insects can tell us about the origins of consciousness (KM: really subjective experience) - a superb, stimulating, thought-provoking article

What insects can tell us about the origins of consciousness | Proceedings of the National Academy...

How, why, and when consciousness evolved remain hotly debated topics. Addressing these issues requires considering the distribution of consciousnes...

www.pnas.org

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Kevin Mitchell

@WiringTheBrain

2 years

I mean, you can see why they'd believe in Asgard... 😲

Morten

@helifliMorten

2 years

Good Morning from Norway…amazing display over Tromsø

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Kevin Mitchell

@WiringTheBrain

6 years

Scientists are simply adults who have learned how to apply a disciplined, highly unnatural method of investigation to the objects of their native curiosity.

Neil deGrasse Tyson

@neiltyson

6 years

Scientists are simply adults who retained and nurtured their native curiosity from childhood.

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Kevin Mitchell

@WiringTheBrain

2 years

No Meaningful [Consistent, Detectable by MRI] Brain Differences in Depression

No Meaningful Brain Differences in Depression

Researchers find that neuroimaging results are unable to distinguish between the brains of depressed people and healthy controls.

www.madinamerica.com

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Kevin Mitchell

@WiringTheBrain

3 months

Just saw a really shocking story of a philosopher who's been faking the results of his thought experiments for years. Shameful.

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Kevin Mitchell

@WiringTheBrain

5 years

That's not the right way to phrase it. About 81% of the variance in risk for autism across the population is attributable to genetic variation. The number doesn't apply to individuals

Spectrum (Autism Research News)

@Spectrum

5 years

About 81% of a person’s chance of #autism comes from inherited genetic factors, according to an analysis of more than 2 million children from five countries.

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Kevin Mitchell

@WiringTheBrain

3 years

For those not aware of how the scientific publishing scam works, it's honestly fiendishly ingenious:

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Kevin Mitchell

@WiringTheBrain

2 years

Current mood... 🍸

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Kevin Mitchell

@WiringTheBrain

5 years

Well, that’s that ruined forever...

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Kevin Mitchell

@WiringTheBrain

5 years

Wow! That's a big "nope" from me. 17 subjects in each group, exploratory analyses, machine learning for extra powerful over-fitting, no replication sample. You could find something similar for any 17 people vs any other 17.

Mandy Paul

@Mandy_Lou_Paul

5 years

Autism: fMRI Brain Scans Can Predict Autism With 97% Accuracy | Time ⁦ @KensingtonRoyal ⁩

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Kevin Mitchell

@WiringTheBrain

5 years

Vaccines are a modern medical miracle. No other medicines have had as profound an effect on our health. To deny them to your children is willful neglect.

Kenan Malik

@kenanmalik

5 years

Public emergency declared in Washington state after measles outbreak in anti-vaccination hotspot:

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Kevin Mitchell

@WiringTheBrain

3 years

No way! Looks like it was designed by Dr. Seuss and H.R. Giger...

Dr Roy Kallivayalil MD

@RoyKallivayalil

3 years

This medicinal #plant ,found only in dark rainy forests is called Oodhu Paavai in Tamil. It blows out pollen grains periodically through its funnel like structure.

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Kevin Mitchell

@WiringTheBrain

3 years

I'm perfecting a kind of reverse multitasking where I'm simultaneously not doing multiple things I'm supposed to be doing...

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