David Fajgenbaum, MD @DavidFajgenbaum Twitter profile

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David Fajgenbaum, MD

3 years

7 yrs ago, I began testing a treatment on myself with the hope that I could make it to our wedding day. Today, we celebrate 7 yrs in remission, a life together with our sweet Amelia, & #ChasingMyCure coming out in paperback.

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

Was such an honor to deliver the @ASCO Opening Address. I shared some thoughts about my talk and 5 key messages while receiving my monthly infusion. It felt like a fitting time to share about being a patient-physician-researcher-caregiver-advocate #ASCO20 #ChasingMyCure

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David Fajgenbaum, MD

@DavidFajgenbaum

3 years

This family of three is going to be a family of four in November! Amelia is going to be the best big sister!

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David Fajgenbaum, MD

@DavidFajgenbaum

3 years

So excited to share that @CFajgenbaum , Amelia, and I welcomed the newest member of our family into the world on Friday! David Carter Fajgenbaum is healthy and so sweet. Caitlin is doing well and we’re so excited (and tired)!

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

It’s hard to believe that today marks ten years since I walked down the hall from my med school exam to the hospital’s emergency department. I knew that whatever was ailing me was bad & that I wouldn’t likely survive.

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David Fajgenbaum, MD

@DavidFajgenbaum

2 years

Today marks 100.00 months that I’ve been in remission on sirolimus—the drug I identified as promising & tested on myself! If you’ve read #ChasingMyCure or asked me how long I’ve been in remission, you’ll know I always share the length of my remission in fractions of months…

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

My heart is broken with the passing of my brother-in-law @ChrisCNC . He was the brother I never had & the best husband/dad. You battled #ALS with so much strength over the last 5 yrs. I’ll keep pushing with everything Ive got to #EndALS & other rare diseases like it. Love you, bud

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David Fajgenbaum, MD

@DavidFajgenbaum

3 years

Really thrilled to see our paper on #CytokineStorm out in @NEJM . @carlhjune & I attempted to define this life-threatening syndrome found in #Castleman , #CART , #COVID19 ,& others to aid clinicians & highlight opportunities for advancing therapies now. #ChasingCures thanks, @EricTopol

Eric Topol

@EricTopol

3 years

Cytokine storm is a prominent feature in severe #COVID19 . This new @NEJM review on it is as good as it gets. By @DavidFajgenbaum @carlhjune @PennMedicine

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

So excited for the awareness being raised about our work to chase a cure for #COVID19 and for #ChasingMyCure ! Please RT/share to help us spread the word about our CORONA project! @cnn @r_prior @CureCastleman

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David Fajgenbaum, MD

@DavidFajgenbaum

5 months

My doctors gave me a 1 in a million chance to find a cure to my disease. To make things worse, I didn’t have a billion dollars and 10 years to develop a new drug from scratch. My only hope was to find a drug that was already FDA-approved that I could repurpose for my disease.

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David Fajgenbaum, MD

@DavidFajgenbaum

5 months

After relapsing on the only drug in development for my rare disease, my doctors told me ‘We’ve tried everything, there’s nothing more that we can do.’ To make things worse, I didn’t have a billion dollars and 10 years to develop a new drug from scratch. My only hope was to find

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David Fajgenbaum, MD

@DavidFajgenbaum

3 years

I’m so thrilled that @NEJM published our #CytokineStorm paper today! As a physician-scientist dedicated to curing CS & a patient who has nearly died 5 times battling #Castleman cytokine storms, Im hopeful this work will help patients like me #ChasingMyCure

Cytokine Storm | NEJM

Cytokine storm, a life-threatening disorder involving cytokine elevations and immune-cell hyperactivation, has various causes and is characterized by constitutional symptoms, systemic inflammation,...

www.nejm.org

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

Despite these challenging times and my lab’s laser focus on #COVID19 , I had such a great 35th birthday today with @CFajgenbaum and Amelia. Even if she made me sit in the refrigerator with her... actually especially since she made me sit in the refrigerator. #BossBaby

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David Fajgenbaum, MD

@DavidFajgenbaum

1 year

Feeling really grateful today for everyone that has supported me as I just learned that I received tenure from @Penn . This was never the goal—its always been to unlock disease mechanisms & save lives. But I’m so thankful for @PennMedicine ’s support & commitment! #chasingmycure

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David Fajgenbaum, MD

@DavidFajgenbaum

10 months

Feeling very thankful for all of the amazing people who have supported our work over the years! Grateful for @PennMedicine @Penn ‘s support of me and our mission to @CureCastleman and unlock @EveryCure ! #chasingmycure

Every Cure

@EveryCure

10 months

We would like to congratulate our co-founder @DavidFajgenbaum for achieving tenure! Please join us in celebrating this incredible accomplishment!

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David Fajgenbaum, MD

@DavidFajgenbaum

5 months

I am beyond honored to be named the 2023 Philadelphia Citizen of the Year by @thephilacitizen . This recognition is a testament to our amazing team's work and the support that so many of you have shared with us! It has been the honor of a lifetime to work with our amazing

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

So honored to follow in the footsteps of @Atul_Gawande , @ScottGottliebMD , & @DrSidMukherjee to deliver @ASCO 's Opening Address tomorrow & share about @CureCastleman & lessons about life & uniting from #ChasingMyCure with leaders in onc #ASCO20 #Castleman

Turning Hope Into Action: How One Physician Is Using His Experience Fighting Castleman Disease to...

If there is one thing the world needs in this moment of COVID-19 darkness, it is a rapid life-saving therapy for a disease we don’t yet understand.

dailynews.ascopubs.org

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

I have loved hearing about how Chasing My Cure has been a source of hope during this difficult time, and I was thrilled to learn that Chasing My Cure became a National Bestseller in May! #chasingmycure #nationalbestseller

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David Fajgenbaum, MD

@DavidFajgenbaum

4 months

I’m so excited to share that I just crossed 10 years in remission! After nearly dying five times in three years and being told there were no more treatments for my disease, I never could have imagined ten years ago that I would be alive today. I could never have imagined that I

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

Luckiest dad in the world!

Caitlin Fajgenbaum

@CFajgenbaum

4 years

Happy Father’s Day to Amelia’s Dada! We are so incredibly lucky to call you ours and we love you so much! 💙💙💙 @DavidFajgenbaum

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

As someone who has nearly died 5 times from Covid19like cytokine storms & lives knowing I could relapse any day, my journey & the lessons I shared in Chasing My Cure feels so relevant right now.

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David Fajgenbaum, MD

@DavidFajgenbaum

2 months

We are so excited to announce a new Research Associate role at @EveryCure for Long COVID and Immunology. This person is going to work with a team of MDs and PhDs to identify treatments that could potentially be used for Long COVID and related diseases. Please click the link

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David Fajgenbaum, MD

@DavidFajgenbaum

3 months

We are incredibly honored to receive this transformative funding from @ARPA_H This funding comes at a pivotal time, allowing us to scale our approach across diseases to pioneer new treatments for millions of people around the world without options. Here’s to chasing cures at

Every Cure

@EveryCure

3 months

Every Cure to Receive $48.3M from ARPA-H to Develop AI-Driven Platform to Revolutionize Future of Drug Development and Repurposing Read the press release here:

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David Fajgenbaum, MD

@DavidFajgenbaum

5 years

Thanks so much, Coach Moorhead! Football helped prepare me for the pain and struggles I would face in the ICU. I’m thankful to have played under you and learned from you. I’ll keep fighting and #ChasingMyCure

Coach Joe Moorhead

@BallCoachJoeMo

5 years

After nearly dying 5 times, my former Gtown QB @DavidFajgenbaum identified a drug that's saving his life & others with #Castleman disease. Read his story of redemption & lessons he learned about living in #ChasingMyCure :

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

Happy, happy birthday to my sweet Amelia (aka Pookie Marie, Monkey Magee, Pookie Magoo)! I can’t believe you’re two! You make me so happy. I hope to one day be able to make you as happy as @Blippi does. And I’ll keep #chasingmycure so I can be with you for as long as possible.

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David Fajgenbaum, MD

@DavidFajgenbaum

3 years

Today marks 11 yrs since Friday the 13th of August when I was first hospitalized for a mysterious illness. I knew I only had days left but began #ChasingMyCure & found a drug that’s saving my life. I learned so many lessons & wrote #ChasingMyCure to share them with the world!

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David Fajgenbaum, MD

@DavidFajgenbaum

2 months

Last week, I had a PET scan to look into my Castleman disease, and also to determine whether I’d had a recurrence in my liver cancer. Great news, the scan came back completely clear and I’m so thankful for that. But it also reminds me that we have so much work to do and at

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

If you’re hoping for a certain outcome tonight, but you haven’t voted, please vote. As someone who’s alive bc I turned my hope into action even when the likelihood of having an impact was extremely low, I’ve learned that hope isnt a passive concept.Its a choice &a force #vote2020

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David Fajgenbaum, MD

@DavidFajgenbaum

3 years

It feels strange to say “Happy #RareDiseaseDay ” On one hand, there’s nothing happy about 7,000+ devastating diseases with <5% with @US_FDA -approved therapies. But on the other hand, this is the most AMAZING community of people who’ve taught me so much on my journey #ChasingMyCure

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

How it started: How it's going: #ChasingMyCure #TurningHopeIntoAction #Overtime

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

This week marks 6 yrs since my last #Castleman relapse/dose of chemo! I didn't think I would make it to Caitlin & I’s wedding or ever have a child. I didn't know if there was a drug that could save my life. But by turning my hope into action & following a few key lessons...

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David Fajgenbaum, MD

@DavidFajgenbaum

1 year

Very cool to see #chasingmycure on @POTUS @JoeBiden ’s desk today! 🙏 to President @BillClinton for sharing a copy with him! And @BackdropBooks for the heads up. #turninghopeintoaction #livinginovertime

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David Fajgenbaum, MD

@DavidFajgenbaum

5 years

Thank you @CNN & @r_prior for sharing about my battle to @CureCastleman for me & thousands of other #Castleman pts & accelerate cures for other diseases. I wrote #ChasingMyCure to share my journey & lessons learned about living from nearly dying 5 times.

Chasing My Cure: A Doctor's Race to Turn Hope into Action; A Memoir

www.amazon.com

CNN

@CNN

5 years

After David Fajgenbaum suffered repeated life-threatening relapses of Castleman disease, he became laser-focused on trying to save his own life. He pioneered a new treatment and an approach to drug research that could help others with rare diseases

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David Fajgenbaum, MD

@DavidFajgenbaum

2 months

Early on in my life I always thought there was a “they” looking for cures across all diseases. Unfortunately I was wrong. In my book I call it the Santa Claus theory of civilization: that for every problem in the world, there are surely people working diligently—in workshops

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David Fajgenbaum, MD

@DavidFajgenbaum

2 months

Huge news! The drug Xolair, which is approved for allergic allergy 20 years ago, has now been repurposed and is now approved for food allergies. A team at the NIH actually approached the drug company that makes Xolair, Genentech, and they decided to partner a few years ago to do

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David Fajgenbaum, MD

@DavidFajgenbaum

3 months

Last night still feels like a dream. Check out my full remarks announcing our partnership with ARPA-H at the White House!

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

How it started: How it's going:

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

What a decade! From my last rites in 2010 to fighting back against #Castleman disease btwn relapses, “I do” in ‘14, Amelia in ‘18, & sharing my journey #ChasingMyCure in ‘19. Here’s to cures for CD & many more diseases next decade! #overtime #hopeintoaction

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David Fajgenbaum, MD

@DavidFajgenbaum

3 years

The most notable side effect I’ve had from the #COVID19 vaccine is a sense of relief. 🚨🚨 @CDCgov @US_FDA #COVIDvaccine

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David Fajgenbaum, MD

@DavidFajgenbaum

3 years

Wow, just wow. A meta analysis in @NatureComms combining all trials of the effectiveness of hydroxycholorquine in #COVID19 finds that hydroxychloroquine is associated with increased mortality in #COVID19 patients... 😧

Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international...

Nature Communications - Hydroxychloroquine and chloroquine have been investigated as a potential treatment for Covid-19 in several clinical trials. Here the authors report a meta-analysis of...

www.nature.com

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David Fajgenbaum, MD

@DavidFajgenbaum

3 years

Thankful for the work done to develop effective #COVID19 vaccines so rapidly and that I was able to get a dose given my immunosuppression and #Castleman #cytokinestorm disorder. ✅ #vaccinated

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David Fajgenbaum, MD

@DavidFajgenbaum

2 years

Happy World Castleman Disease Day! #WorldCDDay I hope you'll RT to help to spread the word about #Castleman disease, a deadly cytokine storm disorder at the intersection of autoimmunity and cancer that thousands of patients are battling…

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David Fajgenbaum, MD

@DavidFajgenbaum

7 months

This photo brings back so many emotions. It was right when I was starting to have my 4th relapse and was told that we were out of options. I had my dad shave a faux-hawk, because I always wanted to have one and my hair was gonna start falling out from the 7-agent chemo. I was

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

I was dying, no treatments. #ChasingMyCure

status annoyicus

@medburnbook

4 years

Tell me why you went into your field in 5 words or less.

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David Fajgenbaum, MD

@DavidFajgenbaum

3 years

Im so excited to announce that Chasing My Cure will be available in paperback on Jan 26th! Ive loved hearing from readers around the world about what its meant to them & how its made a difference in their lives! I’m also so proud that it has 5⭐️ on Amazon from over 250 reviews!

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David Fajgenbaum, MD

@DavidFajgenbaum

2 months

Huge News! AI finds link between Viagra and Alzheimer’s disease! A recent study suggests that Viagra could be a key player in Alzheimer's treatment, thanks to its ability to modulate genes associated with the disease. The study's findings are compelling, indicating a

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

As someone completely amazed by @DrEricDing and the incredible #COVID19 work that he does, I’m so honored and thankful for his comments below and help with spreading the word about our CORONA project and #ChasingMyCure !

Eric Feigl-Ding

@DrEricDing

4 years

David is a genius of our generation. As a doctor and patient, he discovered the cure to his own disease w/ no prior cure... & saved his own life! Now he’s trying to find one for #COVID19 . He’s the real deal- or else he wouldn’t still be here. My friend & hero @DavidFajgenbaum .

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David Fajgenbaum, MD

@DavidFajgenbaum

1 month

Huge news! A drug that doesn't even work on the brain might be a treatment for Parkinson’s disease! A study came out that patients with Parkinson's disease experienced improvement on their symptoms when taking a GLP-1 agonist. This drug similar to Ozempic works directly on the

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

While we have been studying this #CytokineStorm for the last eight years to understand #CastlemanDisease and the immune system-we never thought that a cytokine storm would be the most deadly aspect of the worst pandemic of our lifetimes. #chasingmycure #COVID19

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David Fajgenbaum, MD

@DavidFajgenbaum

3 years

Hope cannot be a passive concept. It’s a choice and a force; hoping for something takes more than casting out a wish to the universe and waiting for it to occur. Hope should inspire action.

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

Happy 4th from the Fajgenbaum’s! 🇺🇸 #amelialovesthebeach #notthesand #orthewater

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David Fajgenbaum, MD

@DavidFajgenbaum

3 years

Thanks @CNN @drsanjaygupta for highlighting the work we’re doing to advance #drugrepurposing for #COVID19 , #Castleman , and other diseases! @id_cure @CureCastleman check out the CORONA project at #ChasingMyCure

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David Fajgenbaum, MD

@DavidFajgenbaum

5 months

While battling for my life in the ICU, a seemingly minor symptom caught my attention amidst the life-threatening failure of my vital organs. Small bumps, known as blood moles, emerged on my chest and shoulders during my relapses. This observation became a critical piece of my

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David Fajgenbaum, MD

@DavidFajgenbaum

1 year

Super excited to share that our work discovering CXCL13 as a novel biomarker in idiopathic multicentric #Castleman disease is out now in @NatureComms ! I nearly died 5X from iMCD during med school--this biomarker could have helped prevent those close calls

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David Fajgenbaum, MD

@DavidFajgenbaum

5 months

A cancer patient’s life was saved by a repurposed drug that was hiding in the medical literature for 3 years! In 2016, Michael came to our center at Penn having been told he had three months to live. We ended up leveraging a tool that we'd built to look back at previous

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David Fajgenbaum, MD

@DavidFajgenbaum

3 years

@AmbientSynthy Would have died from #Castleman disease at 25 years old. Spent months in critical condition in the ICU… that would have been it. Thanks to modern medicine and an amazing team #ChasingMyCure , we identified a drug that is saving my life.

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David Fajgenbaum, MD

@DavidFajgenbaum

2 months

One of the world's most deadly childhood cancers may finally have a cure! Please share this story and message of hope! A patient is now alive more than five years later on a new version of the drug that's actually saving my life as well. Though 98% of kids with this horrible

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David Fajgenbaum, MD

@DavidFajgenbaum

2 months

Ozempic repurposed to treat a rare brain disorder! Just recently a patient went to to share that they have been taking Ozempic to treat their idiopathic intracranial hypertension and no longer have debilitating headaches! This is critical to @EveryCure 's

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David Fajgenbaum, MD

@DavidFajgenbaum

5 months

It's not uncommon to find 15, or even 50, different organizations dedicated to a single rare disease. This is without a doubt holding the rare disease community back. The reality is that compared to more common diseases, rare diseases already face significant hurdles in

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David Fajgenbaum, MD

@DavidFajgenbaum

2 months

With a repurposed mTOR inhibitor…

Arturo LoAIza-Bonilla, MD MSEd

@DrBonillaOnc

2 months

Boy, 13, becomes first person ever to be cured of terminal brain cancer - UNILAD ⁦ @DavidFajgenbaum ⁩ ⁦ @EveryCure ⁩ ⁦ @DefeatDIPG ⁩

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

1M views, #1 story on @cnn & over 10,000 users accessed our CORONA project database, the world’s only database tracking all drugs being used against COVID19. So thankful to our amazing team that is working tirelessly on this critical resource in the global fight against #COVID19

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David Fajgenbaum, MD

@DavidFajgenbaum

3 years

Loved spending the day with my two Valentines in our new house!

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David Fajgenbaum, MD

@DavidFajgenbaum

6 months

Big news! A skin drug has been shown to be wildly effective for one of the deadliest conditions on the planet. Dupixent, a drug initially developed for atopic dermatitis, has now been repurposed for COPD, a deadly lung disease that is one of the leading causes of death for

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

Like everyone, I've been bracing for #COVID19 impact & heeding warnings, but a few things just hit me re: 1) the COVID19 'cytokine storm' 2) that immunosuppressed/comorbid (& elderly) are highest risk & 3) the fear we all have of ourselves or loved ones getting struck suddenly

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David Fajgenbaum, MD

@DavidFajgenbaum

2 years

Always great to see the one and only @DrEricDing and discus #COVID vaccines, @EveryCure , and #chasingmycure @Nasdaq today! #Caatlemanwarrior #WarriorFlex #Flex4Cures

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David Fajgenbaum, MD

@DavidFajgenbaum

3 years

One of the greatest honors of my life was receiving an Atlas Award from @wacphila along with then-VP @JoeBiden for work #ChasingMyCure to @CureCastleman & his @BidenCancer #Moonshot work. Here's to the future of 🇺🇸 & cures to diseases that ail us, @POTUS ! #werestrongertogether

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David Fajgenbaum, MD

@DavidFajgenbaum

6 months

I almost died five times before discovering that the cure to my rare and deadly disease was just a couple blocks away in my neighborhood pharmacy. It begs the question, what other hidden cures are sitting on the pharmacy shelf waiting to be unlocked? #MedTwitter @EveryCure

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David Fajgenbaum, MD

@DavidFajgenbaum

6 months

My mom passed away from brain cancer when I was in college and one of the most important lessons she taught me was in the midst of tough times, don’t just wait for a silver lining – create it. Whether it’s battling a rare disease or facing life’s hardest challenges, it’s about

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David Fajgenbaum, MD

@DavidFajgenbaum

1 year

Thankful for President @BillClinton ’s support of our critical mission to unlock the full potential of existing @US_FDA approved medicines to treat every disease they possibly can! Let’s unlock @EveryCure !

Bill Clinton

@BillClinton

1 year

Fascinating interview with my @ClintonGlobal partner and fellow Hoya @DavidFajgenbaum about his new nonprofit @EveryCure , which repurposes existing drugs to fight other diseases. He saved his own life this way and wants to help millions of others.

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David Fajgenbaum, MD

@DavidFajgenbaum

8 months

Such an honor to share about @EveryCure & our #commitmenttoaction to unlock cures sitting on the pharmacy shelf @ClintonGlobal w/ support from @BillClinton @HillaryClinton @ChelseaClinton @ChanZuckerberg @ElevatePrize @FlagshipPioneer @EmCollective & Lyda Hill. #chasingmycure

Every Cure

@EveryCure

8 months

Co-founder @DavidFajgenbaum gives Every Cure's Commitment to Action at @ClintonGlobal 2023 Meeting!

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

What a year it has been since Chasing My Cure came out. It has been so amazing to hear how #ChasingMyCure has inspired readers, see it reach National Bestseller status, & observe the awareness raised for innovative ways to chase cures.

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David Fajgenbaum, MD

@DavidFajgenbaum

3 years

When I was diagnosed with Castleman Disease I was scared. But I understood you can choose the fear you face. The first being the Santa Claus theory of civilization, where you are like a kid waiting for a miracle. Or the second, the type of fear that forces you to act.

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

Our goal: identify all drugs being #repurposed against #COVID19 and detect signals of activity! We rallied a team of 30 💪volunteers to review 2500+ papers in 11 days & extract data on 100+ drugs already tried for COVID19 in the first 5,000+ patients...

Learn how the CDCN is helping in the fight against COVID19

Our Goal: extract and analyze data on all drugs used for #COVID19 to identify effective #repurposed drugs for patients nowWe rallied a team of 30 volunteers ...

www.youtube.com

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David Fajgenbaum, MD

@DavidFajgenbaum

2 years

A cytokine storm disorder tried to kill me. After finding a treatment that’s saving my life, I now dedicate my life to unlocking new treatments for other patients with these disorders like #Castleman disease. #chasingmycure

Tyler Olson

@olsonplanner

2 years

I went into my specialty because ______________.

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David Fajgenbaum, MD

@DavidFajgenbaum

5 years

I’m so excited that #ChasingMyCure is available TODAY so that our message of hope can be shared with the world! I learned so much about living from nearly dying five times, lessons that I want to share with YOU so you can turn your hopes into action.

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David Fajgenbaum, MD

@DavidFajgenbaum

1 year

Very productive trip to the office! Lots of things were figured out for Castleman disease & @everycure ! Amelia drew some really good circles/immune cells & Baby D did some important paperwork & reading! And some good collaboration happening in the last video. 😂 #chasingmycure

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David Fajgenbaum, MD

@DavidFajgenbaum

5 months

Huge News! The first-ever gene therapy was approved for sickle cell disease! Sickle cell disease, a debilitating condition affecting individuals worldwide, now has a potentially curative therapy. This one-time treatment offers patients the chance to live a full life, free from

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David Fajgenbaum, MD

@DavidFajgenbaum

5 years

Incredibly proud of my Lab, my colleagues, & @CureCastleman ’s study in @jclinicalinvest ! Thankful to @NIH for #R01 funding to make this possible. 1st novel drug target in 25 yrs for iMCD led to precision therapy in 3 pts. Important step forward but lots of work to do! #Castleman

Journal of Clinical Investigation

@jclinicalinvest

5 years

Sirolimus-induced remission in 3 treatment-refractory idiopathic multicentric Castleman’s disease patients @davidfajgenbaum @curecastleman @ThomasUldrick #hematology #immunology

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

#Repurposing drugs for #COVID19 is our best opp to save lives asap. IL-6R blocker tocilizumab is being used (bc COVID19 ignites #Castleman -like cytokine storm). As I shared in #ChasingMyCure , toci was developed by my friend/colleague Kazu Yoshizaki for CD & approved in Japan...

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

I’m so thankful that @nprfreshair had me on to discuss lessons from my journey #ChasingMyCure that are so needed right now and about the work I’m doing to fight back against #COVID19 . #fromhopetoaction

Home - Chasing My Cure

David Fajgenbaum National bestselling author of Chasing My Cure Order Now How Chasing My Cure inspired Every Cure Learn More

chasingmycure.com

Fresh Air

@nprfreshair

4 years

TODAY: @DavidFajgenbaum was diagnosed with Castleman disease when he was a 25-year-old medical student. After nearly dying in the hospital several times (and being told there was no cure) he decided to try and find his own treatment.

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David Fajgenbaum, MD

@DavidFajgenbaum

3 years

Is this what people mean when they say they use their @onepeloton ? Or do people have time to workout these days? #askingforafriend #dadbod #glorydays

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David Fajgenbaum, MD

@DavidFajgenbaum

5 years

I cant put into words what it was just like to meet & enroll the 1st patient into a clinical trial of sirolimus for treatment-refractory iMCD I ID’d this drug while #ChasingMyCure & began taking it myself, now we’re #ChasingOurCures

Home - Chasing My Cure

David Fajgenbaum National bestselling author of Chasing My Cure Order Now How Chasing My Cure inspired Every Cure Learn More

chasingmycure.com

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David Fajgenbaum, MD

@DavidFajgenbaum

5 months

I can’t believe it’s been 10 years since this picture was taken at Global Rare Disease Day at the @NIH . I had been out of the hospital for about a month taking Sirolimus, the drug that’s saving my life. Raj was taking 6-months off of med school to help grow @CureCastleman along

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

My 20-month old Amelia helped me to realize this AM that the immune response in #COVID19 is kind of like Goldi Locks. Not too hot, not too cold. If you suppress it too much w/ tx, you can’t control virus/viral load skyrockets. If you boost it too much, you get a cytokine storm...

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David Fajgenbaum, MD

@DavidFajgenbaum

1 month

Deadly hyperinflammatory disease finds curative treatment from a repurposed drug! DADA2, a rare hyperinflammatory condition, tragically forces children to endure strokes at a young age, often leading to premature death in their teenage years. Without a single clinical trial,

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David Fajgenbaum, MD

@DavidFajgenbaum

9 months

So excited to see our paper on the most effective treatments for idiopathic multicentric #castleman disease pre-published ahead of publication in @BloodAdvances ! @CureCastleman

Treatment consistent with idiopathic multicentric Castleman disease guidelines is associated with...

Key Points. Fifty-two percent of patients with iMCD treated with siltuximab with/without corticosteroids achieved response.Corticosteroids alone are not ef

ashpublications.org

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

Our 1st paper from our CORONA project was published today, reporting all treatments for the first 9,152 published #COVID19 patients. Amazingly 115 different drugs were given. I'm so grateful for the hard work that so many volunteers put into this!

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David Fajgenbaum, MD

@DavidFajgenbaum

3 years

Just as @bsw5020 said, none of us wanted to be a patient advocate. But it is an honor & I also feel a responsibility to do what we can to fight back against disease. Not because we know we’ll win, but because we know we probably won’t & we want to go out swinging for all of us.

Brian Wallach

@bsw5020

3 years

I never wanted to be a patient advocate—I don’t think any of us did. But I am. I wear that title with true pride as I walk in the shoes of giants, fight along side some of the bravest people I’ve met and have the chance to change the world for those to come. Good night moon.

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David Fajgenbaum, MD

@DavidFajgenbaum

5 months

Horizontal thinking saved my life… I didn't have a billion dollars or ten years to develop a new drug from scratch. My survival hinged on one critical strategy: identifying and repurposing an existing drug made for another disease to treat my own. This approach isn't just a

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David Fajgenbaum, MD

@DavidFajgenbaum

3 months

Did you know there are 300 million people worldwide that live with the disease without a single approved therapy? Even worse, the current health care system doesn't incentivize finding cures for these populations because they're often too small. On this Rare Disease Day, we

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David Fajgenbaum, MD

@DavidFajgenbaum

6 months

President Clinton once asked me, ‘What’s Your Dream?’ I had to pause because no one had ever asked me that before. Then I said, my dream is to do what I did for myself but for millions of people around the world. I want to find new uses for all the drugs in your neighborhood

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

Today is #rarediseaseday2020 (& the rarest day of the year)! Watch & share the below video about Rare Diseases (7k diseases affect 30M Americans), #Castleman , & lessons learned about living from #ChasingMyCure .

Chasing My Cure: Dr. David Fajgenbaum Lessons from his Rare Disease...

David Fajgenbaum, MD, nearly died five times. Then, using his own records and blood samples, he found an existing drug that offered hope. In the process, he ...

www.youtube.com

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David Fajgenbaum, MD

@DavidFajgenbaum

7 months

It was such an honor to join @EricTopol on @MedScape 's Medicine and the Machine Podcast where we discussed my journey #ChasingMyCure to now repurposing existing drugs to find @everycure . Click the link below to watch the full interview!

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David Fajgenbaum, MD

@DavidFajgenbaum

4 years

I learned a lot about life from nearly dying 5 times in 3 years. Check out the 5 lessons that I want to share with you at this time of New Years resolutions & reflection on @NPR @WHYYThePulse and my #memoir #ChasingMyCure for more!

5 lessons one doctor learned from the times he almost died

How five near-death experiences drove David Fajgenbaum to live his life to the fullest, and discover a novel treatment for Castleman's disease.

whyy.org

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David Fajgenbaum, MD

@DavidFajgenbaum

7 months

What are your thoughts on Ozempic? This drug is the most talked about repurposing example in the mainstream media because of its unintended weight loss effect. However what it highlights for me is that often, unexpected benefits emerge during clinical trials, and while weight

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David Fajgenbaum, MD

@DavidFajgenbaum

2 years

Should be a fun day! - get Amelia ready for school - submit grant to @US_FDA - discuss status of sirolimus trial #chasingmycure - give keynote for @EVERSANAcompany - host @HHSGov #CORONA mtg - lead @CureCastleman annual physician/researcher mtg - get Amelia ready for bed #goteam

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David Fajgenbaum, MD

@DavidFajgenbaum

1 year

@JoJoFromJerz Chase your cure. Of course, I never knew I would go on to develop castleman disease during my 3rd year of med school and I definitely never thought I’d find a treatment that could save my life and others, but it would have been helpful to receive the encouragement to chase it.

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