Just to add an alternate view, as a young woman who wants to be a parent in the future, I feel like 99% of the societal messaging I get around pregnancy is that it will “wreck you” and destroy your physical body to the point where you are unattractive and undesirable.
This must have been said many times before but it’s kind of wild how having kids wrecks women’s bodies but it isn’t really discussed beyond stretch marks and weight gain.
But the way we speak about these physical changes matters. At best, the words “wrecked”, “destroyed”, “ruined” are serving to dissuade the next generation of parents. At worst, they reinforce the narrative that female beauty and desirability to attached to youth and virginity.
Can’t we prepare women and their partners for the biological adaption of pregnancy (everything from weight gain and skin changes to joint pain and delayed gastric emptying), without using language that degrades women and motherhood?
There are absolutely enormous physical changes (many only temporary) that can range from uncomfortable to medically dangerous. I studied these in medical school and understand them well although I would never speak about an experience I have get to go through.
@ClementYChow
there is an episode of the good doctor where a resident invents crispr and then edits a child’s genome without any pre-clinical trials or FDA approval all in the space of an hour
@ImaniDH_
If you feel that the desire to sleep with/date someone else is stronger than your desire to make your current relationship work, then end it. It's simple. Ending a relationship isn't a character flaw, but lying and breaking your word always is.
something I’ve noticed among the sf tech scene is a tendency to underestimate the complexity of biology in their overestimation of how fast AI will get us to “solving it”
there seems to be this believe that we have all the data, we just don’t know how to interpret it yet
There’s a frequent perception among recent entrants to drug discovery world that if we could just find drug candidates faster, this will be a useful accelerant to the overall process. The issue is: this thinking is mostly (but not entirely) incorrect. 🧵 1/
@giorgiobee
Humble postgrad student but there is an abundance of literature on trauma-induced epigentic reprogramming/maladaptive neuro plasticity via endocrine changes/metabolic changes/oxidative stress/excite toxicity? Is “storing trauma” not just a metaphor to communicate this?
@milquepoast
Being the oldest sibling and studying neuropsych for three years so you can explain to the younger ones that families are not supposed to be this catestrophically dysfunctional
don’t do this, I developed an elaborate plan to move everyone I care about to sf without ever having been there, and THEN IT WORKED but I hate sf and now we’re all trapped in a web of my weaving
@RMcArthur15
@isosteph
Adhd is not a mental illness it’s a neuro developmental disorder. It’s nothing like depression. It can be exacerbated by life circumstances but it is underpinned by a fundamental neurobiological difference.
I am a 5’2” woman who, at the peak of her fitness, could do three pull-ups.
I unironically researched whether I could become a special forces commando at age 18.
I am a young(ish) woman who does want be a parent, but the idea of being a post-fertility woman is so freeing. At twenty-six, every decision in made in the context of knowing what your fertility window is. I want to do so many things with my life-
@Richard_Vixen
I wouldn’t date a men that didn’t have friendships with other women. It’s also fine for men to have friends they find attractive. If you don’t trust your partner to be able to find someone attractive and not sleep with them, then maybe you shouldn’t be together?
What in the living hell is this thread of men who don’t view women as human and capable of conversing/being interested in things other than gossip and talking about boys? You’ve never talked with a woman about politics/science/ideas and found it interesting?
Aside from the sexual aspect, I always found it surprising how women don't really realize that no men want to be friends with women
Most men would far prefer hanging out with other men
Last time I asked a girl to hangout one-on-one in a non-sexual way was probably kindergarten
@KrisLovesDomo
@ImaniDH_
Staying in a relationship that isn't healthy and cheating to deal with it is just another brand of character flaw (acknowledging there are social, cultural and psychological factors that can make it difficult, but that doesn't make it any more ethical)
@ch402
Chris, this is absolutely wonderful. You sound perfectly aligned to my best friend Olivia (medical student who worked at Google as a software eng and studied CS but switched to medicine and comp bio research in cancer to find more meaning in her work). She’d love to connect.
@sbkaufman
We need to shift from “it’s okay if it’s too hard, you are still worthy and brilliant” to “you are worthy and brilliant, and you can do hard things”. Learning that perceiving something as difficult doesn’t mean it’s out of your reach changed my life.
Women wanting kids but having no one to have kids with seems to be, anecdotally, a big problem, especially for educated women. Women who have careers but also want kids have to have foresight and try and plan to be in a stable long-term relationship (ideally marriage) by 30-35.
She’s right, and also, I don’t understand why the declining birth rate is seen as “women choosing to have fewer kids” when often women want more kids than their husbands do.
@_ali_taylor
I lived alone for a few years after being desperate to move out at 18. Now at 24, I am much happier living with a housemate/best friend, and will probably only live with friends or with a partner from now on. So much happier and great for resilience against life stress.
@TaraKreiderLMHC
@MelindaTaub
Never tell a child, “it’s too hard”. Instead, tell them: “it’s going to be hard, but you can do hard things.” My mum raised four kids while running a business on her own. She taught me I could study medicine and want to be a parent at the same time.Hard does not equal impossible.
@opheliamoding
Making college admits dependent on anything not provided to every student in public education (extracurriculars, sports, arts) is a classist move and makes admits almost entirely dependent on parent ability and will to put kids in extracurriculars.
@Uncle_Jerold
My mum had four (all c-sections as I, the oldest, was breach) and said she loved being pregnant. She is an abnormally strong person though and was also back at work a few days after, so she’s by no means the norm!
@nickcammarata
Viktor Frankl’s ‘Man’s Search for Meaning’ and Paul Kalinithi’s ‘When Breath Becomes Air’. In combination they cemented my henceforth unwavering philosophy about purpose, love and life.
I’m sorry but manhattan feels vastly superior to sf, it is just a much more consistent aesthetic, seems to have greater diversity/less homogeneity of thought/interest, and is just more alive?
@Lan_Dao_
Difference in perceived appropriate “settling down” age? Women feel more biological pressure to perceive this as mid-20s to 30s but fewer men do, and thus need to date younger if they want kids in their late 30s/40s.
@atroyn
This. I am shook by how often I see people my age lament about how we’ve never had it worse, “how could I ever bring a child into this world” type stuff
Feeling very hopeful about the future after having the pleasure of joining ninety-six other STEM graduate students and founders in Melbourne for the inaugural
@QuadFellowship
Summit 🧬🥼
So I am mesmerized by the idea of being a fifty-year old woman, family or no family, and being free of my body so my mind can choose how it wants to spend it's time.
@shaindelr
These posts are unbearable to read about my favorite breed of all time. This is my family’s girl and I’ll be getting another (will adopt due to excess) as soon as I settle in a location. I would pay any amount of money to extend her lifespan.
@nwilliams030
Curious to see relationship between sibling no/distance and feelings around parenthood. I’m the oldest of four by a gap of 6+ years so I grew up holding and helping out with babies. Feels instinctual to me and I have no fear about wanting to be a parent when the time is right.
@RomanFeiman
This makes me feel much better about applying for programs this year. I feel disadvantaged as an international student with less than a 4.0 GPA and no full-time research (only part-time) but I have a well-defined research interest, project proposal and targeted prior experience.
@EllieFarrMD
It’s a travesty that we don’t have a system that encourages and facilitates brilliant working women to have and raise more brilliant children. I’m only 23 and starting med school next year, but I would love to have a kid by 35 and sometimes it seems like the odds are against you.
@Aella_Girl
Personally very monogamous with no desire for this, obviously other people can do whatever they want but how is it not universally accepted that validation is a terrible reason?
@_ali_taylor
And I LOVE alone time. Very content with my own company and work/books/nature but there’s nothing better than being able to do that and then debrief with your housemate over dinner or read before bed with your partner.
@Richard_Vixen
Idk I’ve always thought that someone choosing to be with YOU monogamously in spite of ample options was far more loyal/attractive/intimate than someone who is doing it because they don’t have access to alternatives. Choice > coercion.
@ellegist
@recursus
I was extremely apprehensive about the forced swim test until I saw it performed and my fears were alleviated. You don’t even let them dunk beneath the water, you remove them as soon as there is any sign they are going to stop.
@MattWalshBlog
ADHD is about way more than attention…it’s not about paying attention but rather attending to every stimulus all at once - it’s emotional dysregulation, auditory processing and sensory issues. Very clear neurobiological markers of the adhd brain.
I think AI has great potential to augment learning but also could decimate it and result in atrophy. It must be integrated in education as a way to augment understanding, not replace it. A course analogy, but similar to how we have to teach basic arithmetic and wire those path-
That will take decades, and that's fine, because I'd like to think I have a good six or seven of them left in me. But choosing exactly how and where to spend the next decade feels impossible because it is the one that will determine whether I have a family, and with whom.
The ideal male aesthetic is looking like their bodies are the result of natural athleticism and incidental exercise like riding and dueling across the 18th century countryside. A large part of beauty’s attraction is its perceived effortlessness.
There’s an “uncanny valley” at the high end of hotness where most people find you less attractive if you’re too perfect looking. Most women find the guy on the left sexier. Many such cases!
@SWENGDAD
I have dreams where I have babies but they mainly revolve around me negligently leaving them in dangerous places for days/weeks and forgetting. Or they are the size of my thumb. Strange as I have good maternal instinct in the waking world.
@AmandaAskell
Our neuro development is tailored to coming out at 9 months right now - opening eyes and receiving visual info helps wire vision pathways etc. so I think there could be significant neuro development delays if we delayed exposure to external stimuli?
girls only want one thing and it’s a 100 acre hobby farm by the sea where they can live the life of an agrarian wife while doing neurology research in the metaverse
Hiring a UX/UI designer has exponentially improved startup life and I kick myself that we didn’t do this immediately. Huge morale boost to see someone else actualize your vision better than you can.
I want to do an internal medicine or dual neurology-psychiatry residency. I want to do fellowships in immunology and neuropsychiatry. I want to found novel epigenetics hard tech. I want to work for Médecins Sans Frontières three months every year. I want to work on health policy.
-but I can't escape the feeling that I'm too far behind because I won't have them done in time. I would love to keep researching and developing the ideas my startup is focused on (LLMs in biomedical research). I want to finish medical school. I want to get a PhD in epigenomics.
@ellegist
@recursus
Animal models in psychiatry and behaviour are not perfect and there will always be questions about ethics and generalizability, but forced swim test seems like a better option to others which I would not be comfortable participating in (social defeat is truly horrific).
@enlightenedcoop
By that logic there is also no incentive to ever start a job, read a book, or eat a meal. The act of commitment inhibits optionality but the act of refusing commitment inhibits life.
The attitude that it’s only worth doing something if you have innate capacity is absurd and anti-learning/education. I quit extension maths (hardest level of maths in Australian schools) and chemistry/physics because I showed up to class and couldn’t immediately do it-
@lordofgummies33
I hate to say it, but as a former physics major, if you actually want to go into physics you should be the kind of person who finds this level of material completely obvious at 9 years old.
It's absolutely worth studying -- but physics only needs people who are math freaks.
@QuartsClock
@ImaniDH_
I'm genuinely curious if this is really the case...I know not everyone is psychologically predisposed to monogamy but I've never felt any inclination towards polyamory and don't know anyone (in a healthy, fulfilling relationship) who is.
but I think this is ignorant of how much, for example, epigenetic and regulatory data, we have yet to collect (we are still discovering new regulatory features and dreaming up ways to collect data on them)
@nickcammarata
@nosilverv
Twin studies are really not generalizable at all…in fact if you comb through the studies themselves most of the “reared apart” twins were only partially reared apart (late separation, frequent contact), were often kept in the extended family, and were almost always in same SES.
@goldnecklace2
Life altering birth injuries can happen, and we should validate those women and support them through recovery, but many women my age have been persuaded that this is the norm, and it’s not.
@thedulab
I’m many years away from having a family but just moved from Sydney, Australia, where all my family is, to SF, and this is one of the things that weighs on me when I envision the next decade of my life. I grew up being babysat at my nana’s house with my cousins everyday.
@RobertMSterling
Every awesome PhD or MD/PhD PI I’ve met has insisted on being called by their first name, and one that was also a neurosurgeon was the most down-to-earth and chill of them all.
New opinion poll. If you had the chance, would you pick IVF embryos based on a DNA test for educational aptitude?
38% of Americans say they probably would.
🧵
sapiens slander is elitist. I read it as an 18 year old and loved it. My mother (50 year old small business owner who is curious and smart but has no formal education) read it at 50 and loved it. Accessible pop science is good, even if there are more nuanced sources available.
@deepfates
I moved from australia so I have been spoiled with clean air, safety, fresh produce, and nature so even the beauty of the pacific northwest is only as good as every piece of coastline in australia
The Sunset in San Francisco genuinely has the worst vibes of any urban area I've ever been
The vibe is best described as "old video game that didn't include trees to save graphics compute"
Here's a photo (from Google maps because I always forget to take pictures when I go)
@noampomsky
Putting success on a pedestal above other (equally important for flourishing) things like connection and love is fetishized by millennials. I can see a hyper-independence and cynicism of attachments that is not compatible with our neurochemistry or our innate interdependence.
@IvanVendrov
I was in Israel a few years ago chatting to journalists and there was a curious phenomenon of some of the lowest suicide rates despite higher than average x-risk.
@KRHornberger
I have to put down the phone and take deep breaths every time I see a tech bro post about how close we are to genetically engineering allegedly highly genetic traits that have like 40% missing heritability + an enormous unknown/epigenetic or epistatic component
@Lan_Dao_
Also imo men dating younger women who are smart/ambitious is a way for them to date someone who can keep up with them intellectually without being threatening. Success and drive in women is less commonly a pro for similarly-aged partners. Unfortunate.
Reaching the end of five months of after hours in silico syn bio research…website coming shortly - be sure to check out to get our design for a new foundational tool for syn bio R&D.
#iGEM2021
The “how to adapt education to the LLM era” question seems obvious to me: viva voce style oral examinations seem so much more robust than essays and exams, but are too labor intensive for mass use. Why not just use LLMs to administer viva voce examinations?
@Aella_Girl
IQ seems to exist but a lot of the legitimate scientific push back against genetic determinism pertaining to IQ is the invalidity of IQ twin study research.
Reasonable summary here >
🧵Summary of major problem areas in the 6 "twins reared apart" (TRA) studies. Most apply to the well-known Minnesota study.
1) Most identical (MZ) twin pairs were only partially reared apart.
2) Twins share a prenatal environment.
3) Selective adoption placement of twins.
@CatherineDeveny
@coolrunning2009
Can you please explain what was racist about the allied forces giving up their lives and limbs to liberate victims of the Nazi regime?
One of the things that turns me off founder culture is people talking about building to save the world and work on the hardest, most interesting problem, and then the problem is how to get an AI Live Photo sharing app to no. 1 on the App Store.
I cried this morning seeing this announcement. I have watched a parent with treatment resistant PTSD hurt and suffer for more than 20 years due to a dearth in effective treatments. It was the reason I chose to study neuroscience and medicine to try and be a part of the solution.
From 1 July this year, medicines containing the psychedelic substances psilocybin and MDMA can be prescribed by specifically authorised psychiatrists for the treatment of post-traumatic stress disorder and treatment-resistant depression.
Read more:
actually paying a stranger’s vet bills so a family, probably with kids, gets to avoid the misery of not being able to save their pet, giving them more years of joy and a newfound optimism re the generosity of strangers, is good
Joining in on the commentary about physician wages to say that while lifetime potential earning is pretty good in the US, it isn’t okay that residents (who have already gone through minimum eight years of schooling) are paid minimum wage during their prime childbearing years.
@JeffLadish
@Lan_Dao_
The population number isn’t the relevant statistic - it’s the birth rate. With birthdates of lower than two in many parts of the world (sometimes close to 1.3), the risk is an aging population of neuro degenerative disease patients with no one to care for them (taxes, labour).
@RuxandraTeslo
Is it also possible that side effects include nausea and vomiting and women don’t realize that negates the birth control? Source: I am a birth control + nausea combo baby.
@girdley
I think these are industry specific - I worked in politics and wore pencil skirts and tailored jackets with heels, then went to medical school and wore business casual to clinic, and now as a startup founder am told to wear t-shirts so I’m taken seriously.
I finished John Williams’ ‘Stoner’ at 3am this morning and silently sobbed until I could fall asleep.
It is a perfect novel about the battle between the pursuit of passion and the lure of a dissociative endurance in response to the discontent of a human life.
I was raised by an *extremely* neurotic father (police officer) who was diagnosed OCD about child protection and safety. Being raised by a parent who is convinced everyone is going to hurt their child can be very harmful. There is a fine line between protection and stagnation.
The only time I’ve ever wished I wasn’t a woman was in my first year of medical school, eating lunch with a peer at the hospital. He had a packed lunch of nutritious food, snacks, home-cooked etc. and I said “wow, you’re so organized, I just eat frozen meals and canned soup” and…