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Scripps Research

@scrippsresearch

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Scripps Research is one of the world's largest, private, non-profit biomedical research organizations. We are Science Changing Life.

La Jolla, CA
Joined September 2012
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@scrippsresearch
Scripps Research
3 years
Congratulations to Scripps Research’s Ardem Patapoutian, who has been awarded the 2021 #NobelPrize for Physiology or Medicine. Patapoutian wins the award jointly with David Julius, for the discovery of receptors that sense temperature and touch @ardemp
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@scrippsresearch
Scripps Research
1 year
Duplicate images? Almost. This past weekend saw K. Barry Sharpless receive his #NobelPrize at the awards ceremony in Stockholm – the same honor he experienced around this time over 20 years ago. #doubleNobel
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@scrippsresearch
Scripps Research
2 years
Two-time #NobelPrize winner K. Barry Sharpless descends to a round of applause as he arrives on campus and celebrates the news with the Scripps Research community. 👏
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@scrippsresearch
Scripps Research
3 years
In recognition of his trusted voice in science, especially amidst the #COVID19 pandemic, @EricTopol will receive the Gold Foundation Medal. He is honored alongside Dr. Anthony Fauci, Dr. Wayne Riley and hundreds of courageous healthcare workers @GoldFdtn
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Scripps Research
3 years
"I grew up in Lebanon, and I pretty much fled to the U.S. when I was 18. I think it has had a huge influence on me. You know, growing up in a war-torn country, I couldn’t even imagine having a career in science." @ardemp speaks to @sciam & @tanyalewis314
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@scrippsresearch
Scripps Research
2 years
“Click chemistry”—a term Sharpless coined— refers to the LEGO™-like ease of fitting modular chemicals together to form complex molecules. The ingenious platform has transformed how scientists approach drug discovery, bioimaging and more #NobelPrize
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Scripps Research
1 year
Scripps Research's @ardemp arrives in Stockholm with the other laureates ahead of the #NobelPrize ceremony. With @NobelPrize
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@scrippsresearch
Scripps Research
2 years
Professor K. Barry Sharpless is only the fifth individual to have ever been awarded two lifetime Nobel Prizes. 2001 and 2022.
@NobelPrize
The Nobel Prize
2 years
Barry Sharpless has just become the fifth individual to be awarded two Nobel Prizes. He follows in the footsteps of double #NobelPrize laureates John Bardeen, Marie Skłodowska Curie, Linus Pauling and Frederick Sanger. Sharpless was awarded the chemistry prize in 2001 and 2022
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Scripps Research
3 years
“Often times these prizes are given to one or two people, but I want to emphasize that there's a whole field of people working in this area. Specifically in my lab, there’s a big group of young, enthusiastic, smart scientists, grad students & post docs who actually do the work."
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Scripps Research
2 years
We are delighted to announce that Scripps Research's Prof. K. Barry Sharpless has been named winner of this year's #NobelPrize for Chemistry, for the development of click chemistry and bioorthogonal chemistry. Congratulations to all three winners!
@NobelPrize
The Nobel Prize
2 years
BREAKING NEWS: The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”
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Scripps Research
2 years
Congratulations to chemist Prof. Phil Baran, who has been awarded the 2022 Danisco Foundation Science Excellence Award from @IFF . Baran is recognized for advancing science and technology relevant to the future of food, nutrition, and health @BaranLabReads
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Scripps Research
11 months
The Scripps Research Translational Institute, led by @EricTopol , has received $46.8 million in renewed funding over 7 years from @ncats_nih_gov . This will support continued progress in transforming human health through tech-focused innovations @ScrippsRTI
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Scripps Research
3 years
With pioneering #chemistry that has transformed fields ranging from drug discovery to materials science, Prof. Jin-Quan Yu will be the inaugural holder of the Bristol Myers Squibb Endowed Chair in Chemistry @bmsnews @YulabJin
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Scripps Research
4 years
In controlled lab experiments, Profs Hyeryun Choe and Mike Farzan show that a #coronavirus mutation (in this spike) allows it to infect more cells. If this variant causes greater infectivity in people, it could explain differences in severity of outbreaks
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@scrippsresearch
Scripps Research
2 years
We mourn the passing of Richard Lerner, MD, a scientific pioneer who developed technologies that had a major impact on science and medicine, and who played a critical role in shaping Scripps Research and San Diego’s burgeoning life sciences sector.
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Scripps Research
3 years
#cancer needs oxygen to survive, which is why tumors readily sprout new blood vessels. Prof Xiang-Lei Yang’s lab has now discovered a way to prevent this process by inhibiting #HIF and #VEGF signaling @PLOSBiology
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Scripps Research
2 years
The labs of @liye_tsri and Ben Cravatt have made the impossible possible – developing a new method called CATCH, which allows the imaging of specific drugs in tissue to reveal where the compounds are acting in the body @CellCellPress
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Scripps Research
4 years
We are excited to partner with iconic actor @alanalda and the Alda Communication Training Company, empowering scientists and medical professionals to convey complex topics to the public with #ClearAndVivid #communication @AldaCenter @alda
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Scripps Research
4 months
Prof. Jin-Quan Yu has been awarded the 2024 Max Tishler Prize, Yamada-Koga Prize, and Henry J. Albert Award. His trailblazing C–H activation research is reshaping chemistry, with vast implications from drug discovery to material science. More at:
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Scripps Research
10 days
Congrats to our EVP @EricTopol , who is included in the 2024 @TIME #TIME100Health list! The list recognizes the impact, #innovation , and achievement of the world’s most influential individuals in #health . 🎉🌟
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Scripps Research
2 years
Today, the Calibr division of Scripps Research announce promising preliminary data from the first-in-human Phase 1 clinical trial with switchable CAR-T cell therapy. The trial studied the cell product (CLBR001 + SWI019) in patients with B cell malignancies
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Scripps Research
6 months
Congrats to prof. Ryan Shenvi for being awarded the 2024 Mukaiyama Award from the Society of Synthetic Organic Chemistry, Japan. Shenvi is recognized for his contributions to synthetic organic chemistry, notably in complex synthesis. Read more at:
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Scripps Research
2 years
Prof. Chi-Huey Wong is awarded this year’s Tetrahedron Prize for Creativity in Organic Synthesis. Wong’s discoveries have shaped our understanding of complex carbohydrates and glycoproteins, and their role in physiology and disease. @TetrahedronChem
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Scripps Research
2 years
Congratulations to @DonnaBlackmond , who has been awarded the 2023 James Flack Norris Award in Physical Organic Chemistry from @AmerChemSociety .
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Scripps Research
2 years
"The singular and momentous advance in life science that demonstrates the power of AI" - @EricTopol on the ability of #AlphaFold to predict the structures for nearly all catalogued proteins known to science ~200 million @DeepMind
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Scripps Research
2 years
Scientists in @Shenvi_Lab have found a streamlined method for synthesizing compounds found in the bark of trees in Papua New Guinea, which are known for their #hallucinogenic effects and could form the basis of new neurological treatments @ScienceMagazine
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Scripps Research
4 years
As a leader in the field of natural product synthesis, Scripps Research chemist Prof. Ryan Shenvi has been named among the nation’s rising stars as a 2020 finalist for the prestigious Blavatnik National Awards. Good luck Ryan! @Shenvi_Lab @BlavatnikAwards
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Scripps Research
10 months
Scripps Research receives a major award from @NIH to lead key programs in the @AllofUsResearch Program. The Participant Center, directed by @EricTopol & @julialmv , makes the program more accessible to participants & adds new data collection capabilities
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Scripps Research
4 years
Congratulations to Prof. Dale Boger, who has received the #TetrahedronPrize from @ELSchemistry for creativity in organic #chemistry . Discoveries from @BogerLab include durable antibiotics, novel ways to treat chronic pain & an experimental #cancer vaccine
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Scripps Research
2 years
Scripps Research's @ardemp details his life story and explains the groundbreaking work that led to him being awarded the #NobelPrize in Physiology or Medicine in 2021. Dive into the full video and Q&A in our latest Scripps Research Magazine feature
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Scripps Research
2 years
With promising preliminary results in patients with B cell malignancies, Calibr’s “switchable” chimeric antigen receptor T-cell (sCAR-T) therapy platform is the 1st step towards development of a universal, more versatile, and safer approach to cell therapy
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Scripps Research
4 years
US benefits tremendously from those who come from abroad to offer their intellect, talent & energy. We strongly oppose the order blocking H-1B & other work visas. We extend gratitude & support to international scholars contributing so much to science & culture at Scripps Research
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Scripps Research
10 months
Prof. Keary Engle has been awarded the 2023 Leo Hendrik Baekeland Award from @AcsJersey . Engle is recognized for his accomplishments in pure and applied chemistry, as well as the creativity and leadership displayed in his approach to research. @EngleLab
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Scripps Research
2 years
Starting soon! Register for free and tune in at 1pm PT
@scrippsresearch
Scripps Research
2 years
Tune into our free #FrontRow lecture this Wednesday (1pm PT). @tajayiMD will show how clinical scientists are using smartphone and other digital technologies to revolutionize #MaternalHealth and reduce population disparities. Register here:
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Scripps Research
2 years
Congratulations to Scripps Research’s @xinjin , who has been selected for this year’s prestigious 35 Innovators Under 35 list by MIT’s @techreview . Jin is recognized for her development of gene-editing tools to understand the origins of #autism #TR35
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Scripps Research
2 years
Some scientists suggest #omicron may have evolved in the immunocompromised, while others suggest it may have developed after passing back into animal species. Prof. Kristian Andersen discusses in @statnews @helenbranswell
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Scripps Research
2 years
"I went into Barry's office to say congratulations, and he went to the blackboard. All of a sudden, he's giving me a lecture about sulphur chemistry." - Vice President Jamie Williamson, pays tribute to #Nobel laureate K.Barry Sharpless. Highlights from the prize toast on campus.
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Scripps Research
10 months
The Scripps Research community mourns the passing of Michael Oldstone, MD, esteemed virologist and professor emeritus, who helped establish the viral pathogenesis field and shaped our understanding of host immune responses
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Scripps Research
1 year
Chemists from @BogerLab have devised the first general method for synthesizing a family of compounds called 1,2,3,5-tetrazines, which hold great promise for making pharmaceuticals, biological probes and other chemical products @ACSPublications
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Scripps Research
2 years
Two Scripps Research faculty are recipients of this year’s Baxter Young Investigator Awards. @nani_grotjahn who studies mitochondrial stress and @xinjin who focuses on neurodevelopment and autism. Congratulations Danielle and Xin!
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Scripps Research
3 years
With diverse expertise ranging from protein engineering to mitochondrial stress and autism, we welcome three new members of faculty: Ahmed Badran, PhD; Danielle Grotjahn, PhD; and Xin Jin, PhD @AhmedHBadran @nani_grotjahn @xinjin
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Scripps Research
3 years
“Growing up, my idea of a scientist was from the cartoon Dexter’s Laboratory.” Despite pressure to follow a more traditional career, Huang pursued research to become an expert in #glycobiology . Science with a view @HuangMia #WomenInSTEM #WomenInScienceDay
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Scripps Research
3 years
Congratulations to Scripps Research chemist @hanzyduzit who has been awarded a prestigious @SloanFoundation Research Fellowship for his work using enzymes to make challenging #anticancer , #antiinflammatory and #antimicrobial compounds #SloanFellow
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Scripps Research
3 years
Pioneering biochemist Jeffery Kelly has been awarded the Breakthrough Prize in Life Sciences 👏 The award recognizes Kelly’s work elucidating the molecular basis of neurodegenerative and cardiac transthyretin diseases @brkthroughprize #BreakthroughPrize
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Scripps Research
2 years
Congratulations to Prof. Benjamin Cravatt, who has been awarded the prestigious #WolfPrize for pioneering innovative protein-based technologies that have gone on to shape anti-cancer drug discovery @WolfPrize_ @grobbins
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Scripps Research
1 year
We welcome Yuzhong Liu to Scripps Research, who will join the Department of Chemistry to develop improved vaccines and medicines using synthetic biology. Learn more about her research:
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Scripps Research
4 years
The recent @NatureMedicine paper by @K_G_Andersen and colleagues on the origins of the novel #coronavirus receives unbelievable attention online and in the news, speaking to its impact #2019nCov #COVID19 @altmetric
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Scripps Research
6 years
"Ending Alzheimer's" Living longer does not always mean living better. Scripps researchers are changing that as they pursue a cure for Alzheimer’s. Give now to support this life-saving work: #AlzheimersDisease
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Scripps Research
11 months
Congratulations to @nani_grotjahn , who has been named a 2023 Pew Scholar in the Biomedical Sciences. The award will support Grotjahn’s study of how cells assemble the molecular machinery that governs programmed cell death @pewtrusts
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Scripps Research
4 days
Congrats to Prof. Benjamin Cravatt for receiving the 2024 Bristol Myers Squibb Award for Enzyme Chemistry from the @ACS_DivBioChem . His work in activity-based protein profiling revolutionizes treatments for neurological disorders and cancer. 🎉🌟 More at:
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Scripps Research
1 year
In huge effort involving @IAVI , @fredhutch & @NIH , scientists in Prof. William Schief’s lab have revealed promising results in the first-in-human clinical trial of a novel #HIV vaccine. Targeted response achieved in 97% of those vaccinated. @ScienceMagazine
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Scripps Research
3 years
In collab w/ @IAVI , researchers led by Prof. William Schief have confirmed a novel #HIV #vaccine approach in the first human clinical trial. Vaccine works to prime the #immunesystem as the first stage in the production of broadly neutralizing #antibodies
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Scripps Research
3 years
Thanks to the pioneering work of prof. Chi-Huey Wong spanning over 40 years, the field of #glycobiology came to be. Knowing how cellular sugars operate has since led to medicines for #influenza , #cancer & #HIV . Learn more in the Scripps Research Magazine
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Scripps Research
5 years
Congratulations to Jin-Quan Yu, PhD, who has been elected to the prestigious American Academy of Arts and Sciences. Yu has broken down barriers in organic synthetic chemistry to create versatile compounds with enormous public benefit. #sciencechanginglife
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Scripps Research
2 years
Congratulations to Scripps Research Professor K. Barry Sharpless for being awarded the Sir Derek Barton Gold Medal from the Royal Society of Chemistry! Read more: @RoySocChem #RSCPrizes #chemistry #clickchemistry
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Scripps Research
2 years
We welcome Alejandra Mendoza to our growing faculty, who will join as an assistant professor in the Department of Immunology and Microbiology. Mendoza’s lab will illuminate the interwoven circuits that drive inflammation, pain and immunological diseases
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Scripps Research
4 years
By hijacking enzymes from bacterial strains in Scripps Research’s Natural Products Discovery Center, Profs. Hans Renata & Ben Shen have been able to make complex, medicinal molecules that are usually only obtainable from plants @ScienceMagazine @hanzyduzit
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Scripps Research
2 years
No more #flu shot? Scientists at @scrippsresearch @WCMpeds @UChicago @ScienceLife have identified a new Achilles’ heel of influenza virus, making progress in the quest for a universal flu #vaccine
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Scripps Research
8 months
In a synthetic chemistry feat reported in the journal @Nature , Scripps Research scientists devise a method for C-H activation of alcohols.
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Scripps Research
4 years
175 years since first use of #ether , but the way general #anesthesia works has remained a mystery, until now. Scott Hansen and Richard Lerner labs show that the compounds rearrange the lipids in cell membranes, leading to unconsciousness @PNASNews
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Scripps Research
2 years
Scripps Research’s @YulabJin have developed a new method for the easy, versatile synthesis of molecules called lactones, which could boost industries from pharmaceuticals to plastics @ScienceMagazine
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Scripps Research
5 years
Congratulations to Scripps Research’s Ben Cravatt for winning the prestigious Jeremy Knowles Award from the Royal Society of Chemistry. Wonderful recognition of Ben’s pioneering work and overall contributions to the chemical sciences.
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2 years
Elegantly mixing art & science, researchers in the Center for Computational Structural Biology have produced the very first 3D model of an entire cell, representing a new way to visualize cellular environments in health and medicine @MartinaMaritan #sciart
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Scripps Research
3 years
"We should probably prepare for this being the predominant lineage in most places in the United States by March." A new analysis led by @K_G_Andersen projects continued spread of #B117 #SARSCoV2 variant, which could lead to increased strain on healthcare
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Scripps Research
4 years
From #inflammation , to #arrythmias and impaired blood flow, the effects of #COVID19 on the #heart are becoming a growing area of concern. @EricTopol details in @ScienceMagazine #SciMagPerspective #SARSCoV2
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Scripps Research
1 year
Prof. Jefferey Kelly has received the 2023 Wolf Prize in Chemistry. It recognizes his research developing therapeutic strategies that amend toxic misfolded proteins that aggregate in the body—a hallmark of many diseases, including Alzheimer’s @WolfPrize_
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Scripps Research
2 years
Chemists from @YulabJin & @UCLA have developed methods for the precise, flexible modification of a class of chemical compounds called bicyclic aza-arenes, opening up discovery of potential blockbuster drugs that were previously out of reach @Nature
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Scripps Research
2 years
Congratulations to Scripps Research neuroscientist @xinjin , who has been named the recipient of the 2022 Early Career Investigator Award from the International Society for Autism Research (INSAR) @AutismINSAR
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Scripps Research
2 years
In a tribute to Richard Lerner in @ScienceMagazine , current Scripps Research President & CEO, Peter Schultz, reflected on Lerner's remarkable creativity in bridging fields of chemistry, immunology & medicine, generating a legacy of scientific enterprise
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Scripps Research
3 years
Congratulations to Prof. Chi-Huey Wong for the Robert A. Welch Award in #Chemistry . Wong is recognized for his instrumental work over the past three decades on carbohydrates in active immunization & treatment of cancer & infectious disease @WelchFoundation
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Scripps Research
5 years
An institute’s faculty should be recognized not just for their independent research, but also their commitment to education and mentorship. Congratulations to chemist Keary Engle for winning the Camille Dreyfus Teacher-Scholar Award. @EngleLab
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Scripps Research
4 years
Vaccine candidate from @Novavax shows promise in ongoing clinical trials. Now, structural mapping from the Ward Lab shows the #coronavirus spikes keep the desired shape in this #vaccine , which should help stimulate appropriate #immune responses @WardLab1
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2 years
Congratulations to Professor Sandra Encalada for receiving $4.1 million from NIH to advance her work on #prion diseases! The research could also help better understand additional neurodegenerative diseases. #neuroscience #brain
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Scripps Research
2 years
Two studies from Prof. Bill Schief’s lab & collaborators describe an approach to design a custom HIV vaccine that can coax the immune system to produce the right broadly neutralizing antibodies in a stepwise manner @ImmunityCP @ragoninstitute @moderna_tx
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2 years
The Wolf Foundation awarded Cravatt the prize for “developing activity-based protein profiling, which has emerged as a powerful and widely used chemical proteomic strategy to characterize enzyme function in native biological systems.” @WolfPrize_
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1 month
The @YulabJin lab has streamlined the complex creation of saturated heterocycles, which are essential in many FDA-approved drugs. This innovation is pivotal for quicker, more efficient drug development. More:
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Scripps Research
2 years
Neuroscientist @xinjin receives both the Larry L. Hillblom Foundation Award & the Klingenstein-Simons Fellowship Award in Neuroscience, recognizing emerging independent scientists who show promise in improving the understanding of neurological disorders.
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4 years
Huge #COVID19 development - team led by the Burton Lab discover antibodies in blood of recovered patients that protect against #coronavirus in animals. Researchers now focus on making large quantities of these to test in clinical trials @ScienceMagazine
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Scripps Research
3 years
Congratulations to Scripps Research fellow Danielle Grotjahn, PhD, who receives a prestigious 2021 Innovation Award from @DamonRunyon Research Foundation for her approach to studying #mitochondria fragmentation in #cancer progression @nani_grotjahn
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Scripps Research
2 years
Congratulations to Scripps Research’s @xinjin , who has been awarded the 2022 Rising Star Award from @OneMindOrg , for developing genetic screening technologies to identify the underlying biology and risk factors for neuropsychiatric disorders
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Scripps Research
1 year
Congratulations to Scripps Research’s @xinjin , who has received dual awards from @CIRMnews and @genome_gov , that will support Jin’s research identifying how certain risk genes implicated in autism spectrum disorder influence brain development #ASD
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Scripps Research
2 years
A new drug developed by Prof. Stuart Lipton’s lab coats the SARS-CoV-2 virus with chemicals that can temporarily alter the human ACE2 receptor, meaning that when the virus is near, its path into human cells is blocked @nchembio
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Scripps Research
2 years
We welcome Shannon Miller from @Harvard , who will join the Scripps Research Fellows Program. Miller will be advancing delivery methods for novel gene-editing technologies, with the potential to accelerate therapeutics for genetic diseases @_ShannonMMiller
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3 years
New molecular tools developed by @disney_lab are able to break up disease-causing #microRNA or prevent assembly, depending on which tool is selected. Preliminary experiments show the compounds can prevent #BreastCancer as well as #AlportSyndrome @J_A_C_S
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4 months
Scripps Research is home to some of the world’s leading chemists, who advance our ability to design and produce molecules, develop life-changing therapies, and tackle global sustainability challenges. Learn more:
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Scripps Research
2 years
From soapsuds to gold! Chemists in Prof. Jin-Quan Yu’s lab have developed powerful method for transforming simple, cheap chemicals - aliphatic acids - into complex and valuable ones. @YulabJin @ScienceMagazine
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2 years
Combining her experience with those of other #LongCovid patients, @julialmv and the @scrippsdtc team have designed a study to see if #wearables can help improve symptom management. Learn more online in the Scripps Research Magazine:
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Scripps Research
1 month
In a new @ScienceMagazine study, the @Shenvi_Lab , with @BaranLabReads , converted feedstock chemicals into quaternary carbons with a single, inexpensive iron catalyst that could lead to cheaper and easier production of drug molecules. More:
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3 months
The City of San Diego declares today "Scripps Research Day" in honor of the institute's century of discoveries into life-saving medicines, as well as for its influential force in shaping the local bioscience community. Learn more:
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2 years
Using synthetic biology methods, Prof. Mia Huang’s lab have developed a platform for building and modifying protein-sugar conjugates called #proteoglycans , which has revealed their role in cancer cell spreading and stem cell maturation @HuangMia @nchembio
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4 years
“Heavy hydrogen” to halt heroin. New preclinical findings from Prof. Kim Janda’s Lab show that using the heavy hydrogen form #deuterium in an experimental #opioid #vaccine can vastly increase its ability to stop #addiction behaviors @AmerChemSociety
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3 years
An early start for @ardemp this morning...
@NobelPrize
The Nobel Prize
3 years
Just in! New medicine laureate Ardem Patapoutian and his son Luca, watching the #NobelPrize press conference shortly after finding out the happy news. Stay tuned for our interview with Patapoutian coming up soon! Photographer: Nancy Hong
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@scrippsresearch
Scripps Research
3 years
Early-stage results from Prof. Jiang Zhu’s lab show that an experimental #COVID19 #vaccine using virus-shaped particles to stimulate an #immune response performs well against three major “variants of concern” @lab_zhu
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@scrippsresearch
Scripps Research
2 years
Highlighting the importance of improved pandemic surveillance, @K_G_Andersen 's lab has integrated genomic, epidemiological and travel data to reveal the key drivers of SARS-CoV-2 transmission in the Middle East @NatureComms
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@scrippsresearch
Scripps Research
2 years
The Skaggs Graduate School at Scripps Research has earned another top ten ranking, according to @usnews . The only non-university-based program on the list! Chemistry program ranks 6th in nation and Bio Sciences program ranks 9th @ScrippsGradPrgm
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@scrippsresearch
Scripps Research
4 years
Sensational synthesis! A landmark “click” chemistry discovery made earlier this year, including Scripps Research’s Nobel laureate K. Barry Sharpless, gets named as one of the most important scientific highlights of 2019 by @nature and @cenmag
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