Well, it's official. My wife I are both joining the faculty at the University of Colorado
@CUAnschutz
this summer! I will join the Dept of Biochemistry & Molecular Genetics
@CU_BMG
& she will be joining the Div of Cardiology
@CUCardiology
and the Cancer Center
@CUCancerCenter
Ground breaking analysis here. As you get older your ability to tolerate low wages and lack of a stable position drops. I finished my PhD at 27, started my postdoc at 28 and will start my independent career at 34. But I’m one of the lucky ones. Change is badly needed.
For those who followed just to hear the big news, here it is: It's my great honor to be joining the
@NIGMS
family with this K99/R00 Pathway to Independence Award 🙏 It's been such an emotion few days, but I'm incredibly excited to be able to keep doing what I love 😭❤️ short🧵
Hey
@Stanford
, wanna rethink YOUR postdoc pay scale? I suggest you look up COL in Memphis and compare it to Palo Alto. Also, see how the amount goes up each year? Would be nice if we had that too. It’s radical to think that institutions with $$ may have to spend some of it 😒
Structural Biology at St. Jude Children's Hospital
Incredibly excited to share our work online today as an
#OpenAccess
article in
@CellCellPress
😍 This process taught me some things that I'd like to share, a short 🧵
Academia: we need more diverse faculty!
Also academia: we can’t afford to pay you more than 55k/yr, so have you considered having family wealth?
Also it’s not our fault blame
@NIH
Solidarity with
@UniCalifornia
#ucstrike
JUST KIDDING.
Infant daycare at UCSF Mission Bay will be
***$3,190.00 per month***
Starting postdocs make $4,636/month (pre-tax).
So $5,969 in JUST rent and daycare.
😭
Hard not having FOMO seeing all the posts about
#ACSSpring2023
*and*
#DiscoverBMB2023
going on right now. So many cool people I wanted to meet/hang out with. But turns out I had another very important person to meet this weekend 😍
Daycare: your child has a temp of 100.5, threshold is 100.4, so you need to pick them up.
Scientist parent: your instrument reports 2% accuracy and has 0.1 s.e.; I believe this is shot noise. Please re-take 100 times over next 10' and send me stats and recent calibration file.
I’m actually going to call bullshit on this. I am positive that you can fill ~50% of your speaker slots with women and not compromise in ANY way on merit with ease.
3/4 Selecting speakers based on identity politics instead of merit will greatly reduce the quality of any conference. I’ve known
@kurtilaszlo
for years. He loves his students, is very well respected in the field, and is one of the fairest and most honest people I know.
Hey
@Stanford
, me again. You okay? Us postdocs are getting worried you can’t do basic math. Also, requiring guarantors for housing shames those who come from poor fams. No one in my fam would ever have been able to meet these requirements & I’m not alone.
One-day off on my "next-day" Tweetorial, but here is it! TL;DR we found that PIPs regulate GPCR desensitization/internalization/signaling by gating when and where arrestins bind. This explains some ago-old phenomenology in the field. See 🧵👇for details!
🚨 65 days and counting!! 🚨 It is my GREAT pleasure to announce an exciting
#GPCR
meeting you're not going to want to miss
@cool7TMs
Some MAJOR details here👇 pls RT!
Doubt he’ll remember this particular moment, but yeah too many academics assume that it’s just hours working that dictates your success. Be kind to yourself. Take time for friends and family. You can never get back this time ❤️
#dadademia
“He retired from Stanford in 2004, a day before his 66th birthday, in part, he said, to make room for up-and-coming faculty members.”
Amazing to have this level of humility and vision. How many sr. faculty members would do this today?
@Caroline_Bartma
1995 CNS: “look at these cool experiments we did to test some hypotheses and learn something new”
2020 CNS: “look at how much money we have to sequence everything get a lot of data and present it in heat maps no one can understand”
Let me just say that work is work. Maybe it's not doing experiments, but writing, reading, paper reviewing and making talks/posters are integral parts of our WORK. These should NOT be viewed as tasks to be done "on our own time"
@AcademicChatter
@PhD_Balance
Finally! So great to see this paper finally published after hearing the story what seems like forever ago ~ congrats to the super-star
@bignerdzzy
and of course
@kevansf
and everyone else involved 🥳
Been watching the faculty candidates from one of the departments in my building (not mine). Three from Harvard (+subsidiaries) and one from CalTech.
Seems they're really leaving no stone unturned in their search for the best candidates 🥲
Excited to share our work, and my first (co-)first author postdoc paper showing how a GPCR is engaged by a beta-arrestin! Was a fantastic team effort to make this happen 👏🏼
@AcademicChatter
#gpcr
#arrestin
Things I've learned in the last 48 hours:
1. Twitter LOVES cute baby photos
2. Some people have very very sad lives 😭
3. The intimate details of Stanford's "Children in the workplace" policies 🤓 Fun fact: my fun photo violated no university guidelines or policies 😍
As 2023 comes to an end I look back on a year that brought me my highest highs and lowest lows.
On one hand, my wife and I welcomed our son into the world and both accepted dream asst. prof. positions.
On the other, today I lost my dad to cancer and am shattered.
👋 2023.
Yesterday’s inspiring posts for
#FirstGenDay
reminded me that because I “look the part” I hide in plain sight. I’m an only child from a poor family who only dreamed of Higher Ed. 10 yrs ago I graduated from
@UofT
then got a PhD at
@Harvard
before coming to
@Stanford
.
Saying that
#ACSSpring2024
isn’t the place to speak up about your beliefs has some big anti-take a knee movement energy. If someone has the courage to speak up about their values we should let them, and maybe listen. Chastising her or both sides-ing is plain weird behaviour.
I’m grateful to present at
#ACSSpring2024
but I can’t share my work w/o recognizing that we are losing our fellow chemistry researchers, profs & students from the ongoing genocide in Palestine.
I pray for scientists 1 day sharing their work at ACS from a safe & healed Palestine.
Interested in GPCRs, beta-arrestins, and how lipids can modulate their interactions? Come to my
#ASBMB2022
talk tomorrow in the Lipids interest group (Rm 120 C 12:45-2:45 pm). 🙏 to
@airola_lab
and
@JohnEBurke2
for the invite
#EB2022
2nd yr
@UCSF
I got hit by a truck bike-commuting to lab and was badly hurt.
UC student insurance covered $0 .
I was left completely on my own, so I sued the trucking co. to pay my medical bills.
My winnings are why I got through grad school debt-free.
#FairUCNow
These new pallets are absolutely beautiful - already downloaded and started playing with these colors. Awesome work
@BlakeRobMills
🤩 ~ now the hard part, will my next paper be Kandinsky, Paquin or Tam? 😕
#RStats
#dataviz
✨✨ PACKAGE UPDATE ✨✨
MetBrewer 0.2.0 is officially out 🥳 Available both on Cran and through my GitHub here:
New Palettes are out and some amazing new features. Full description of what has changed below :)
#MetBrewer
#rstats
#r4ds
#dataviz
Busy couple of days, but incredibly productive. Feeling like I got
#newPI
bingo - got asked whose lab I was in at recruiting, people got lost looking for my makeshift office and I got lost myself trying to get around 🙃. Bye for now CO 👋, see ya soon
#BPS2024
😍
Is there a Marie Kondo equivalent for organizing my pseudo-chaotic folders of
#postdoc
data, lab notes, and to-do lists that are no longer timely or relevant. Asking for a friend.
@AcademicChatter
When I was a third year grad student a postdoc I was working with in the lab told me “you’ll be a professor in the future, but you need to know you’re not going to get a JJ [me] in your lab for some time. Maybe never.” …
Hey
#GPCR
tweeps, I'm trying to compile a list of junior PIs (group LDR/Asst.&Assoc. prof) who are ~0-10 years into having their labs. Looking to make it easy to identify speakers for upcoming mtgs. Please suggest names & RT!
Often the dialog about life in academia is stressful. Grants ND, papers rejected, etc.
But this week reminded me of the best parts of it - I spent the beginning of the week visiting
@C_P_Lapointe
‘s new lab
@fredhutch
and playing with his new microscope 🚀
6.5 years in the making 👩🏼⚕️🫀. Many things have changed since then, but some things stay the same, like celebrating with Veuve and Chinese food 👌🏻 congratulations to my amazing wife on passing her cardiology boards 🎉
@Stanford_WIC
@StanCVFellows
Today is a special day for me. 10 years ago this story was published in
@NYMag
. It represents a past life, one most of you will not know about. A life where I could never have dreamed of being the elite amateur athlete I am today. A short🧵
Friday hot take: posts criticizing this 👇 seem mostly bad faith. Invitations to give talks has never been egalitarian. You are not owed an invitation to speak anywhere. If you are active in your research community and known for giving great talks, people will want you to speak.
Something I didn't fully appreciate about this job until recently: if you make friends with great scientists, then you can just invite your friends to give talks! And/or others will invite them, and you can enjoy it when your friends come to town!
Working through analyzing my data and realizing that I should have paid better attention during that linear algebra class I took in college
#AcademicChatter
Thanks
@DDB_MPGPCR
🙏 for an amazing meeting. So impressed with the level of science and discussions. Always great to reconnect with old friends and make some new ones, too, and I can’t wait to visit again🇦🇺
Had an amazing time hosting
@joann_trejo
from
@UCSDPharm
at
@Stanford_MCP
today - we got to hear about both her fantastic science as well as her forays into leadership and major contributions to promoting inclusive excellence in STEMM 👏 thanks for visiting us! ❤️
Congrats
@jieheng7
and team on this awesome use of NCL and sortase chemistry to prepare a number of homogeneously modified b2ARs - lots still to learn about how
#PTMs
regulate these receptors!
@mike_feigin
I remember when I first learned “environment” was a factor in grant review and thought “won’t this just mean that money goes to the most prestigious places disproportionately?”
This really is a dream come true - as the son of a secretary and a security guard, I was the first in my family to attend college. My father didn't finish high school. Here he is 🤯 at my Harvard graduation. I wish you could be with us today, dad, but I know you'd be proud.
Important NON-science and NON-cycling update 🚨… 6 years ago today my best friend said yes. 4 years ago today she said I do. And this year she said… “can you make me breakfast if I take the dog out?” 😂
Monday will mark 11 years (!) since the
@HarvardCCB
orientation that marked the beginning of graduate school for me. Inspired by this post by
@JSheltzer
I wondered what the stats looked like for my cohort. A 🧵
Living a split life 💔 Photos taken almost exactly 12 hours apart - from race sims with the team to post-bedtime prepping samples for cryo-EM. With time in between going to family it really makes for a long day 😮💨 & not easy to balance ⚖️
#dadademia
#scientistathlete
I'm stunned by how
@SarahJ_Piper
(
@PiperProteins
) brought my idea to life with this stunning rendering of
@buildmodels
7SBF (uOR-Gi-PZM21) ~ but maybe I'm... biased 😬 -- GPCR peeps if you've not submitted your abstract for the
@cool7TMs
symposium, the deadline is in <48 hours!
Ep.145 of the Dr.GPCR Podcast is out! 🎧 Listen to Dr. John Janetzko as he talks about what sparked a challenging passion for studying and understanding the molecular basis of G protein-coupled receptor desensitization and trafficking.
▶️
#gpcr
#drgpcr
Faculty member: what can we do to make postdoc experiences better?
Postdocs: hold my pipette (not literally)
But seriously, it’s nice to see a receptiveness to the issue vs saying it’s not a solvable problem, so thanks
@StearnsLab
- here are *my* Stanford-specific points 👇🏻
@Caroline_Bartma
“We offer solutions that work” Our ethanol water mixtures contain just the right balance of dissolved organic molecules and ions to meet all your needs.
Great start to my day! 🥳
@DamonRunyon
announced their latest class of physician-scientist awardees, ft. my amazing wife! After years of clinical training
@StanfordMed
@StanCVFellows
I can't wait to see what you discover in the lab! Check out her research👇
Many here probably don’t know my family (mother’s side) is Ukrainian. I don’t have family there now (that I know), but being raised in the Ukrainian community in Toronto has made the news extra hard to swallow each day. Hopefully there is peace soon. 🇺🇦
So this one is bittersweet. We've been working on a similar story; we knew this was coming, but it didn't take away that gut punch when I finally saw the paper this AM. But sometimes you get beat. That's science. If you'll indulge me, a short🧵 on being scooped
#AcademicTwitter
Our paper “GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision” is out today! We use single-molecule FRET imaging and other biophysical approaches to explore the structural dynamics of β-arrestin1 activation upon binding GPCRs. (1/6)
It still feels surreal that this little kid went on to: be a
#firstgen
college student, move to a new country, get a PhD, do a postdoc, and now get his first independent
@NIH
grant! The Janetzko lab will be looking for a home this Fall 👀 so hmu if your dept. is hiring! 🙏
Now, I hope I can use this chance I've been given to make academia accessible for more people, to give to my students/trainees the same kind of learning/mentorship/support I benefitted from and to do some really kick-🍑 science! 🔬🧪🧫 Thanks ya'll for reading 🥰
PSA: with lots of downer stuff happening in the world it’s important to be good to yourself and take mental health breaks from your phone/computer. Happy Saturday 👋
Excited to use this weekend to focus on important research program Aim 1: determine if he likes sweet potato or carrots more. Aim 2: optimize spoon to mouth food delivery methods. Aim 3: investigate use of dog for food clean up - busy weekend ahead!
#dadademia
@NICHD_NIH
After a late arrival yesterday stoked be starting on a high note -
@tim_stasevich
talking about some cool single molecule tracking of endogenous proteins
#BPS2024
- join us in ballroom B, this symposium has a stacked lineup 🤩
#newPI
folx: what are things you bought new that you wish you'd bought used? Related: what did you buy used that you wish you'd bought new/had a better warranty on?
#sciencetwitter
@peiferlabunc
@SluskyLab
Dude. So much good science is in JBC. It’s been really sad seeing the rise in Nat Comms and related journals over more publishing in society journals that people are themselves members of. Brand chasing combined with easy transfer makes Nat Comms the default if you want NPG
@S__Baksh
Was pretty wild when Stanford residents/fellows were considering this. I remember hearing at grand rounds faculty spouting off anti-union propaganda including: "we pay well, [compared to other subspecialities] so if there is collective bargaining your salary may go DOWN" 🙃
Finally made it to
@MIPS_Australia
for
@DDB_MPGPCR
2023 - so grateful to be part of this meeting and incredibly excited for the cutting-edge science to come these next few days 🤩
Such wonderful news this morning!
@CarolynBertozzi
has been a scientific hero of mine for so many years and I couldn’t be happier for her 🥳. It’s also kind of a big deal that KBS gets his 2nd Nobel! 🤯 right
@andrei_yudin
?