Ruslan Medzhitov @RMedzhitov Twitter profile

Last Seen Profiles

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@mikeyperk

@AveAnim

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@Argenddoesstuff

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@DPihtoo

@susie_taylor

@AzzyFord

@girlcel_

@peacock_da62083

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@starszye

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@matgonor

@iFluffyPotato

@eliteexped

@McglothinL89984

@Koirandoshil

@huhnazira

@roisonheart

@BigFutaBooty

@itineratur

Ruslan Medzhitov

@RMedzhitov

4 years

What we learned so far: Least appreciated jobs are most essential Tony Fauci is a national treasure It is hard not to touch face Zoom meetings are totally fine Every idiot is suddenly an epidemiology expert The fate of this civilization depends on antibodies to a spike protein

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Ruslan Medzhitov

@RMedzhitov

4 years

As predicted (by epidemiologists), now it is immunologists’ turn to be lectured on Twitter by people who don't know what the fuck they are talking about.

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Ruslan Medzhitov

@RMedzhitov

4 years

As we anticipate lock-downs.. Cambridge had to shut down in 1665 due to plague. Newton spent the next two years in confinement in Woolsthorpe. During that time, he discovered Calculus and the laws of Optics. This was the greatest intellectual productivity in human history..

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Ruslan Medzhitov

@RMedzhitov

4 years

This virus has revealed many gaps in our knowledge of infection biology. For example, why are the worst assholes on the planet not getting infected despite being exposed?

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Ruslan Medzhitov

@RMedzhitov

4 years

Read this morning how an army of teenagers torpedoed our moron-in-chief’s stupid racist rally. Was going to tell my daughter only to find out that she was one of those teenagers (booked 6 tickets a week ago). Best father’s day present ever!

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Ruslan Medzhitov

@RMedzhitov

3 years

Taught by hundreds of millions of years of experience, the immune system would never start wound healing process until it completely clears the pathogen that caused the damage. Healing the wound before infection is cleared makes the infection and damage much worse. 1/2

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Ruslan Medzhitov

@RMedzhitov

4 years

Just explained Bayesian probability to my (13 yo) daughter, and now I believe I deserve a drink!

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Ruslan Medzhitov

@RMedzhitov

4 years

About 2.7 billion years ago, a toxic gas (a byproduct of an energy harvesting mechanism) wiped out most of life on Earth. Some organisms survived by hiding from it. Others started using it for their own energy generators and became dependent on it. That 'toxic' gas is oxygen.

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Ruslan Medzhitov

@RMedzhitov

4 years

A plot for a very bad movie: a poorly studied + strand RNA virus jumps from bats to shut down the world; a generously proportioned supreme leader may or may not be dead; a self-proclaimed very stable genius tells his followers to drink bleach and put shiny objects up their asses.

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Ruslan Medzhitov

@RMedzhitov

4 years

The fucking nightmare is over!!!

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Ruslan Medzhitov

@RMedzhitov

5 years

This is f-ing awesome!

neuro.social.self

@neurosocialself

5 years

Japan: Intercellular signal transduction during the assembly of slime mould cells • cAMP-sensitive fluorescent probes • signal is transmitted as a spiral wave within the group • amazing • via @kotapub

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Ruslan Medzhitov

@RMedzhitov

4 years

Wow! This is f-ing awesome!

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurp...

An outbreak of the novel coronavirus SARS-CoV-2, the causative agent of COVID-19 respiratory disease, has infected over 290,000 people since the end of 2019, killed over 12,000, and caused worldwide...

www.biorxiv.org

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Ruslan Medzhitov

@RMedzhitov

2 years

Our new study on macrophage-fibroblast communication circuit with implications for tissue compartment size control:

Microenvironmental Sensing by Fibroblasts Controls Macrophage Population Size

Animal tissues are comprised of diverse cell types. However, the mechanisms controlling the number of each cell type within tissue compartments remain poorly understood. Here, we report that differ...

www.biorxiv.org

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Ruslan Medzhitov

@RMedzhitov

4 years

'The failures to contain the outbreak and to understand the scale and scope of its threat stem from an underinvestment in and an under-appreciation of basic science.' Coronavirus Is What You Get When You Ignore Science

Opinion | Coronavirus Is What You Get When You Ignore Science (Published 2020)

Scientists are all we have left. Pray for them.

www.nytimes.com

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Ruslan Medzhitov

@RMedzhitov

4 years

This will be the end to the US science.

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Ruslan Medzhitov

@RMedzhitov

4 years

People who now have to work risking being infected (Nurses, ICU docs, delivery, cleaning and other support staff, grocery stores clerks, etc.) should be exempt from paying taxes for the next 100 years.

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Ruslan Medzhitov

@RMedzhitov

3 years

Sunset. View from my window right now.

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Ruslan Medzhitov

@RMedzhitov

4 years

Holly shit, this is so painful to watch..

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Ruslan Medzhitov

@RMedzhitov

3 years

Science tweeps: What aspect(s) of inflammation biology do you find most confusing, with current 'textbook' explanations unsatisfying? If there is consensus on what needs discussion, I will try to incorporate into review I am working on.

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Ruslan Medzhitov

@RMedzhitov

3 years

Just got my copy of the 2nd Ed of this great textbook by Paul Schmid-Hempel, which I would recommend to all immunologists - it fills many important gaps in standard immunology courses

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Ruslan Medzhitov

@RMedzhitov

5 years

You can't define a nonlinear system without first defining a linear system, or define energy without first defining work. Similarly, you can't properly define inflammation without first defining homeostasis.

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Ruslan Medzhitov

@RMedzhitov

4 years

This is a fucking CDC director. What a disgrace.

Aaron Rupar

@atrupar

4 years

"First I want to thank you, for your decisive leadership ... I also want to thank you for coming here today ... I think that's the most important thing I want to say" --CDC Director Redfield slathers Dear Leader-style praise on Trump during his tour of CDC headquarters

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Ruslan Medzhitov

@RMedzhitov

4 years

oh, and I almost forgot - fuck trump and every mf who supports and enables that filthy racist sack of shit

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Ruslan Medzhitov

@RMedzhitov

3 years

Say what you want, but it’s nice to have a President who is not the absolute worst piece of shit.

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Ruslan Medzhitov

@RMedzhitov

6 years

Our Review on "Emerging Principles of Gene Expression Programs and Their Regulation": Would welcome any feedback.

Emerging Principles of Gene Expression Programs and Their Regulation

Transcriptional responses to external signals can consist of many hundreds of genes that can be parsed into different categories. Pope and Medzhitov discuss the structure of transcription programs...

www.cell.com

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Ruslan Medzhitov

@RMedzhitov

4 years

Please sign and RT. Get your deans and department chairs sign it too.

Dr. Ushma Neill

@UshmaNeill

4 years

Citizen scientists, please sign this petition written together with Ruslan Medzhitov @RMedzhitov as a signal of support for our immigrant colleagues. The more of you who support this, the more powerful it will be to our electeds. #ImmigrantScience

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Ruslan Medzhitov

@RMedzhitov

5 months

Highly recommend this book to anyone interested in the biology of diseases. A systematic explanation of what, how, and why, can go wrong resulting in a particular spectrum of human disorders. The book is a foundation for a new branch of biomedical science.

uri alon

@UriAlonWeizmann

5 months

Why do we get certain diseases whereas others do not exist? This new book builds a foundation for systems medicine. Starting from basic laws, it derives why hormone, immune and aging circuits are built the way the are, culminating in a periodic table of diseases.

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Ruslan Medzhitov

@RMedzhitov

2 years

Given how crazy contagious Omicron is even with the usual precautions (masks, etc.), I wonder if it can infect by ocular route (in addition to respiratory route).

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Ruslan Medzhitov

@RMedzhitov

4 years

Although on the past we always started the course with a lecture on why immunology/infection biology are important, this year we gonna go ahead and skip that part.

Prof. Akiko Iwasaki

@VirusesImmunity

4 years

@rjhomer57 @YaleMed Thanks, @rjhomer57 😊 @RMedzhitov and I will be teaching #immunology to @YaleMed first year students again this year. This tweetorial is a little primer for a much more detailed discussion of the immune system. And yes, we are using @BioRender slides for all our lectures 💪🏼

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Ruslan Medzhitov

@RMedzhitov

4 years

Everybody hates Newton now.. inventing calculus and shit.. during a pandemic.. what a prick..

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Ruslan Medzhitov

@RMedzhitov

3 years

Word

Andrew J Phelan

@ajphelo

3 years

You want a @time person of the year? Here he is.

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Ruslan Medzhitov

@RMedzhitov

3 years

@GOP hypocrites can fuck right off with their 'healing' message. 2/2

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Ruslan Medzhitov

@RMedzhitov

2 years

Also zero randomized trials on not jumping off the roofs

Vinay Prasad MD MPH

@VPrasadMDMPH

2 years

Zero randomized trials on masking in school Zero randomized trials on masking kids Zero randomized trials on masking adults in high income nations Zero randomized trials on masking anyone in cities Zero randomized trials of school closure Zero randomized trials business closures

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Ruslan Medzhitov

@RMedzhitov

4 years

Haiku: Because it's full of garbage, I thought I'd quit Twitter today. And then I saw this..

Sofía Villalpando

@sofiabiologista

4 years

Inside the chromatophore cell, pigment granules are enclosed in an elastic sac, called the cytoelastic sacculus. To change colour the animal distorts the sacculus form or size by muscular contraction, changing its translucency, reflectivity, or opacity 🦑

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Ruslan Medzhitov

@RMedzhitov

3 years

Et tu, 2021 ?!

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Ruslan Medzhitov

@RMedzhitov

4 years

Huge congratulations to Dr. Zuri Sullivan @zurisullivan who had her brilliant thesis defense today! Over hundred people by zoom, from everywhere from Japan to South Africa to California, including 4 generations of mentors, family (including grandma!) and friends!

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Ruslan Medzhitov

@RMedzhitov

2 years

Absolutely gut-wrenching madness, but there is a hope the good will prevail #StandWithUkriane

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Ruslan Medzhitov

@RMedzhitov

5 years

If you are interested in history of biomedical science, read this book. If you are not, definitely read this book.

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Ruslan Medzhitov

@RMedzhitov

4 years

We have happy hour by zoom every Friday with my lab. Today we had an 'unhappy hour'.

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Ruslan Medzhitov

@RMedzhitov

3 years

Most disease have normal physiological counterparts. Here is our views on food allergy from ecological and physiological perspectives. Should be accessible at this link.

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Ruslan Medzhitov

@RMedzhitov

4 years

Brasil, você é o próximo!

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Ruslan Medzhitov

@RMedzhitov

4 years

A haiku: My lab closed today I feel dead inside And yet...

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Ruslan Medzhitov

@RMedzhitov

4 years

This will not age well, unfortunately. Also, Rudy is a fucking moron.

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Ruslan Medzhitov

@RMedzhitov

4 years

A plot for an awful sci-fi movie: A stupid asshole takes over the country, his opposition can’t get their shit together, but the world is saved by a coronavirus. Everyone dies in the process, but a couple of hippies who were too stoned to notice there was anything untoward going.

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Ruslan Medzhitov

@RMedzhitov

3 years

I probably shouldn't brag about it, but just spent a few minutes solving these problems, including the first one!

Dr. Amanda Charlesworth 🏳️‍🌈

@AGCharlesworth

3 years

I made some little games for my lab mates kids' using @BioRender and I wanted to share with you all! Feel free to print them and give them to kiddos who love (or who you are slowly convincing to love) science! Happy Holidays everyone!

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Ruslan Medzhitov

@RMedzhitov

4 years

What the fuck is wrong with this guy?

Donald J. Trump

@realDonaldTrump

4 years

SAVE THE POST OFFICE!

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Ruslan Medzhitov

@RMedzhitov

4 years

@VirusesImmunity @leitzkejs @rkhamsi Macrophages are your cellular equivalent of 'essential workers'. Some of them immigrate into the tissue, some already assimilated. But one thing for sure - they get the job done!

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Ruslan Medzhitov

@RMedzhitov

4 years

Every news about COVID-19 should start with this reminder 👇🏼

Scott Galloway

@profgalloway

4 years

from 2 yrs ago: Trump administration cuts 80 percent of CDC's efforts to prevent global disease outbreak

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Ruslan Medzhitov

@RMedzhitov

3 years

Thank you all for your comments. Sounds like collectively we find pretty much all aspects of inflammation 'most confusing'. Maybe a sign we need to upgrade the foundation? After all it is more than 100 years old.

Ruslan Medzhitov

@RMedzhitov

3 years

Science tweeps: What aspect(s) of inflammation biology do you find most confusing, with current 'textbook' explanations unsatisfying? If there is consensus on what needs discussion, I will try to incorporate into review I am working on.

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Ruslan Medzhitov

@RMedzhitov

5 years

This is one of the most important papers in the field of autoimmunity.

uri alon

@UriAlonWeizmann

5 years

A physiological counterpart for autoimmune diseases, explaining why certain T cells that attack normal body cells might be essential. Endocrine autoimmune disease as a fragility of immune-surveillance against hypersecreting mutants

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Ruslan Medzhitov

@RMedzhitov

5 years

Deep down, we are all GMOs.

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Ruslan Medzhitov

@RMedzhitov

2 years

Just finished watching ‘In the same breath’ - a documentary by Nanfu Wang about the pandemic from its early days in Wuhan. Heavy stuff. A must watch.

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Ruslan Medzhitov

@RMedzhitov

4 years

@guacamolebio "The trouble with the world is that the stupid are cocksure and the intelligent are full of doubt." Bertrand Russell

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Ruslan Medzhitov

@RMedzhitov

5 years

Our perspective on metabolic control strategies and their evolutionary origins.

Control strategies in systemic metabolism

Nature Metabolism - The authors of this Review present a framework for understanding fundamental principles of metabolic regulation, drawing analogies between metabolic control and economic theory...

www.nature.com

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Ruslan Medzhitov

@RMedzhitov

4 years

With senate republicans sometimes you can't tell if they are being stupid AF or just evil.

Rand Paul

@RandPaul

4 years

Great news! - Pfizer vaccine 90% effective - Moderna vaccine 94.5% effective - Naturally acquired COVID-19 99.9982% percent effective* * (estimating 200 reinfections out of 11 million Americans, which is likely an overestimation of actual reinfections)

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Ruslan Medzhitov

@RMedzhitov

4 years

Holy fuck!

The Daily Show

@TheDailyShow

4 years

Hannity. Rush. Dobbs. Ingraham. Pirro. Nunes. Tammy. Geraldo. Doocy. Hegseth. Schlapp. Siegel. Watters. Dr. Drew. Henry. Ainsley. Gaetz. Inhofe. Pence. Kudlow. Conway. Trump. Today, we salute the Heroes of the Pandumbic.

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Ruslan Medzhitov

@RMedzhitov

4 years

It is so nauseating to listen to that stupid fuck.

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Ruslan Medzhitov

@RMedzhitov

4 years

Note to self: don't drink and tweet about sharks..

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Ruslan Medzhitov

@RMedzhitov

2 years

@OdedRechavi this would reveal a lot of speaker's passwords

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Ruslan Medzhitov

@RMedzhitov

3 years

If somebody says: "It's more of a comment than a question" it's only fair to reply with: "It's more of a comment than an answer"

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Ruslan Medzhitov

@RMedzhitov

4 years

Yep, sums it up nicely

Leah B. Gilliam, MD

@DrGRuralMD

4 years

😂 I didn’t create this, but I wish I had. This is real life, y’all.

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Ruslan Medzhitov

@RMedzhitov

4 years

The law of jealous mediocrity: For every Mozart, there is a Salieri, For every Fauci, there is an Atlas.

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Ruslan Medzhitov

@RMedzhitov

5 years

We think Adiponectin and the rest of CTRP family may function as lipid binding opsonins or lipid carriers, rather than canonical hormones. This would clarify many strange aspects of #Adiponectin biology. #Metabolism

Adiponectin and related C1q/TNF-related proteins bind selectively to anionic phospholipids and...

Adiponectin (also known as Acrp30) is a well-known adipokine associated with protection from cardiovascular disease, insulin resistance, and inflammation. Though multiple studies have investigated...

www.biorxiv.org

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Ruslan Medzhitov

@RMedzhitov

4 years

New Report Finds Americans Willing To Trust Scientific Knowledge Of Anyone Holding Glass Beaker Up To Light via @theonion

New Report Finds Americans Willing To Trust Scientific Knowledge Of Anyone Holding Glass Beaker Up...

WASHINGTON—A new report released Monday by the Pew Research Center Monday revealed that Americans were much more willing to trust the scientific knowledge of anyone holding a glass beaker up to the...

www.theonion.com

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Ruslan Medzhitov

@RMedzhitov

2 years

Read the room, Monkeypox. Read the f #king room.

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Ruslan Medzhitov

@RMedzhitov

2 years

Boa sorte amanhã, meus amigos brasileiros!

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Ruslan Medzhitov

@RMedzhitov

5 years

Thank you - so happy it got "Cool AF" rating!

Aleks Deczkowska 💔

@ADeczk

5 years

soooo gooood! made me think in a new way. and so well written - music! || Control strategies in systemic metabolism by Jessica Ye and @RMedzhitov ||

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Ruslan Medzhitov

@RMedzhitov

3 years

Plato's job interview: -And who did you train with? -Socrates -How do you spell .. you know what, never mind. Any notable trainees? -Aristotle -Okey-dokey, we'll call you if anything opens up!

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Ruslan Medzhitov

@RMedzhitov

4 years

This paper reads like a thriller! Congratulations @OdedRechavi for achieving your goal of publishing (what will likely be THE most read) paper, with zero physiological relevance and no mechanism!

Oded Rechavi

@OdedRechavi

4 years

Here’s a wild story on how we tried to piece the Dead Sea Scrolls “puzzle” by sequencing ancient DNA extracted from the animal skins on which the scrolls were written. Please read the @CellCellPress paper, retweet and checkout my short thread👇

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Ruslan Medzhitov

@RMedzhitov

4 years

CNN messed up the headline again. Should read: Dr. Fauci calmly corrects some pompous dick.

Lucy Kalanithi

@rocketgirlmd

4 years

Dr. Fauci is a national treasure

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Ruslan Medzhitov

@RMedzhitov

4 years

So are we watching this thing or fuck it?

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Ruslan Medzhitov

@RMedzhitov

5 years

And the same with chronic inflammation:

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Ruslan Medzhitov

@RMedzhitov

4 years

This guy is a dangerous clown.

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Ruslan Medzhitov

@RMedzhitov

4 years

One moron is out, one to go

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Ruslan Medzhitov

@RMedzhitov

4 years

Simple – when you remove everything non-essential (The Good) Simplistic – when you remove something essential (The Bad) Complicated – when you add something non-essential (The Ugly)

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Ruslan Medzhitov

@RMedzhitov

5 years

There is one thing we can all agree on: Somebody should invent a WTF emoji.

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Ruslan Medzhitov

@RMedzhitov

3 years

@LabRandolph Parasites can manipulate the system to start healing before clearing, leading to chronic problems. This applies to both helminths and republicans.

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Ruslan Medzhitov

@RMedzhitov

4 years

For what it's worth, I agree completely that effective vaccines will be developed against Covid and there is no need to despair. The only social distancing we'll need to maintain is from the anti-vaxxers. It's a win-win.

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Ruslan Medzhitov

@RMedzhitov

3 years

Awesome. I would've put 'Understanding' instead of 'Wisdom'

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Ruslan Medzhitov

@RMedzhitov

4 years

OK, I’m gonna go throw up now

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Ruslan Medzhitov

@RMedzhitov

2 years

TFW the top gene in your sophisticated RNAseq experiment is called 'Similar to XP000371-like 2'

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Ruslan Medzhitov

@RMedzhitov

4 years

I have to say I have a lot of respect for @MittRomney now. He's the only GOP senator to stand up against that fucking imbecile in the WH. And now this..

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Ruslan Medzhitov

@RMedzhitov

4 years

After watching The Irishman, now every time I will get a rejection of any sort: Me: "It is what it is.." My inner voice: "It is what it is?" Me: "It is what it is!"

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Ruslan Medzhitov

@RMedzhitov

2 years

If you are interested in network theory, we just posted our manuscript on @ArXiv . This is the work of a brilliant postdoc Miri Adler @MiriAdler : 1/9

Emergence of dynamic properties in network hyper-motifs

Networks are fundamental for our understanding of complex systems. Interactions between individual nodes in networks generate network motifs - small recurrent patterns that can be considered the...

arxiv.org

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Ruslan Medzhitov

@RMedzhitov

4 years

problem solved, now back to that zoom meeting..

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Ruslan Medzhitov

@RMedzhitov

2 years

Dang it, that's why mosquitos find me so attractive! I've been wondering about it for years. Very cool study from @EllenDeObaldia and @leslievosshall

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Ruslan Medzhitov

@RMedzhitov

4 years

👇🏼

AAI

@ImmunologyAAI

4 years

AAI Councillor Akiko Iwasaki prepares for her visit with Senator Christopher Murphy. #AAIHillDay

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Ruslan Medzhitov

@RMedzhitov

5 years

Mosquitoes in Japan bow and apologize before and after biting you.

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Ruslan Medzhitov

@RMedzhitov

2 years

@OdedRechavi @TelAvivUni so this whole time you were in just a temporary space??

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Ruslan Medzhitov

@RMedzhitov

4 years

Well, today can officially go fuck itself.

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Ruslan Medzhitov

@RMedzhitov

4 years

This is like when a teenager boy tries to ask a girl for a dance and she is sooo not interested and he pretends he was just passing by to get some soda.

Rafael Martín Ledo

@rmartinledo

4 years

Guys, this is one of the most spectacular encounters I've ever filmed! And I'm sure these are the weirdest creatures you will see today! Specimens from Northern Atlantic Phase contrast microscopy Video by @rmartinledo

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Ruslan Medzhitov

@RMedzhitov

4 years

Thank you!

Annual Reviews

@AnnualReviews

4 years

@VirusesImmunity A timely topic indeed. So you know, we removed access control from ALL 51 journals (not just those with #Covid_19 content) to support faculty & students with the rapid transition to remote learning caused by the pandemic .

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Ruslan Medzhitov

@RMedzhitov

4 years

By now it's like, bring it on, bitch! #Fuck2020

david alexander

@DavidADC

4 years

tomorrow is the second friday the 13th in 2020; the first was in march

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Ruslan Medzhitov

@RMedzhitov

4 years

Есть два типа людей: те кто читали Братьев Карамазовых, и те кто не читали. “There are two kinds of people: those who have read The Brothers Karamazov, and those who have not”. (A Russian saying)

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Ruslan Medzhitov

@RMedzhitov

4 years

From the glorious nation of Kazakhstan.. Sasha Baron is a genius.

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Ruslan Medzhitov

@RMedzhitov

4 years

if you have maga friends/family members, please let them watch this.

Maya Harris

@mayaharris_

4 years

It’s the humility and sincerity for me...

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Ruslan Medzhitov

@RMedzhitov

6 years

Next time you have 10 min to spend on Tweeter, listen to these lectures instead:

Critical Thinking

www.youtube.com

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Ruslan Medzhitov

@RMedzhitov

2 years

The Answer to Stopping the Coronavirus May Be Up the Nose

Opinion | The Answer to Stopping the Coronavirus May Be Up Your Nose (Published 2022)

Why nasal vaccines for Covid could be so effective.

www.nytimes.com

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Ruslan Medzhitov

@RMedzhitov

4 years

👇🏼👇🏼👇🏼

The Daily Show

@TheDailyShow

4 years

Meanwhile in 2018...

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Ruslan Medzhitov

@RMedzhitov

2 years

@LabListon I don't think we know the answer. Of all sickness behaviors, fever and loss of grooming are two most enigmatic. Kluger's work on iguanas from 70s shows it is adaptive but unclear why.

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