As we anticipate lock-downs.. Cambridge had to shut down in 1665 due to plague. Newton spent the next two years in confinement in Woolsthorpe. During that time, he discovered Calculus and the laws of Optics. This was the greatest intellectual productivity in human history..
@RMedzhitov
Originality needs imagination, that in turn needs time and an adequate environment... So you convinced me; I can't wait to do my isolation, (But wait... what should I do with my adorable non sleeping baby?)