Me: Explaining Glass half full or half empty?’ and the relation to optimism/pessimism
my 10 yo: ‘That’s silly bc it depends on what happened just before. If someone is pouring the water, it’s half full. If someone is just drinking it’s half empty!’ 🤯
Rev 3: the results do not replicate one prior paper in humans. Reject.
Me: Exactly. We used same methods and don’t replicate. Hence, this should be published so folks like YOU don’t go around thinking we already know the answer!!!
My science family is broken forever. Sarah - you were a shining star who led with grace and always had something fun and mischievous to share. We will always feel your absence. ❤️
Just heard that
@sarahdubrow
, an amazing colleague and human being, passed away over the weekend after enduring a sudden and painful illness. This is beyond heartbreaking. Sarah was brilliant in every way. Sincerest condolences to her family and friends. News via
@LilaDavachi
.
Everyone at home - please take this time to prioritize getting sleep if you can! It’s so undervalued in our society but also vital to physical and mental health. If children want to sleep in, let them! Extra sleep is superior to 2 extra hrs of work ! Trust.
Great news from NIH! They’ve greatly expanded their definition of diversity.. and now includes individuals who are the first to go to college! Take a look!
@Tash_Stanton
@NicoleStoutPT
I am cracking up 😂 reading this thread - thanks all for sharing, you are not only great thinkers but hilarious too! (i wanna be your friend!). (I was having FOMO about missing SFN but no more). But it is SAD that we ALL have experienced this. It’s too much.
Time to stop hiding because the eye patch may be here to stay. It’s been over 2 years since surgery, attempting recovery during a pandemic while home schooling kids, losing my father and trying to keep it all together. This is my face, this is my story.
Thank you
@SfNJournals
for highlighting this ambitious work by
@emilytcowan
. It was a massive undertaking linking learning, overnight sleep polysomnography, and next day memory reactivation in the fMRI scanner! Stay tuned for more results from this massive project!
#JNeurosciAnnualSpotlight
2020 |
@emilytcowan
,
@LilaDavachi
et al. used fMRI in humans to conclude that the oscillatory pattern of brain activity known as sleep spindles might participate in the restructuring of memory traces during memory consolidation.
So grateful this morning for science + medicine. My daughter had 103 fever yesterday (strep) and today with amoxicillin is able to swallow again and no fever. 🙏🏼 I have faith that science + medicine will do the same for covid-19.
#fundscience
Email from our 9 yr old:
Subject: me being bad
i know what i did was wrong and i will do my best next time and one thing that could help me is remind me every day that I CAN NOT SAY SHUP UP TO YOU OR DADDY so please forgive me
ps can i have 1000 robux?
Precisely.. science is incremental and reliability builds across time. If you read any ONE paper and decide it’s ‘amazing’ or ‘crap’.. that’s not scientific. Every paper is a little right and a little wrong, it’s our job to clarify those points over time.
This is why I constantly tell people what it means to have scientific consensus. If we all agree, that’s rare and it means *that* is science. A single paper is not science per se.
Wonder how individual episodic memories trade off with schematic knowledge? Here is some data that requires revising existing theories. Another gem from the fierce
@AlexaTompary
!
Now out in Scientific Reports! We found that as episodic memories fade, they become more influenced by newly learned schemas - even though the schemas themselves fade over time too. A pleasure to work with
@LilaDavachi
& WenXi Zhou.
Cortico-hippocampal contributions to pattern separation (CHiPS) reviews how automatic and controlled processes coordinate with the hippocampus in distinguishing highly similar inputs. Super fun to hash out these ideas with Tarek!
Happy to share my latest paper with
@LilaDavachi
where we propose a framework focusing on the role of cortical regions in pattern separation. Now out in
@eLife
!
So proud of these 3 amazing scientists
@wangjing_yu
@john_thorp
@camillecgasser
who presented their MA research talks in
@ColumbiaPSYC
. Resilience in research: amazing projects that emerged during the pandemic. (cherry on top: it’s also my bday!)
Teary-eyed saying goodbye to the amazing
@DavidClewett
as he leaves NYC for CA and his faculty position. Working with him has been amazing. His enthusiasm for science is rare and it lifts up everyone around him. Thanks for spending time in my lab, Dave! ❤️
Memory reinstatement is evident in both cortex and hippocampus but pattern separation only seen in hippocampal ECoG patterns! Congrats to Professor Lynn Lohnas on her first ECoG paper! And it all started with Katherine
@duncanlabUofT
!
I’m trying to make it joyful setting up his laptop for the morning. But in reality it brings tears to my eyes to introduce our son to 4th grade this way.
#pandemiclife
#coviddiaries
Day 6: My 9 year old just said ‘Its nice having all four of us home and not doing other things. It’s like we’re a family’
#coviddiaries
Some insight into how we sometimes don’t know what we need or want until we have it.
Memory based prediction violations shift internal hippocampal CA1 dynamics towards entorhinal and away from CA3, consistent with the notion of pushing the hipp into an encoding vs retrieval ‘state’!
Excited to have this one out! care about the hippocampus or prediction error? we got both! Extremely thankful for the wonderful
@duncanlabUofT
@LilaDavachi
, and for the support of past and present Davachi lab members!
Agreed! My parents came here from Iran the year I was born — my dad a doctor with some friends in Nashville. I owe more to my mom in many ways who herself was barely 20 and left everything she knew behind. All for us. Immigrant sacrifice is real.
Sometimes forget to be grateful to be a US citizen, but got talking w
@aa_fenton
about how our parents immigrated to America, and it reminded me to hold on to the inspiration and courage our parents had:
THREAD (1/n)
RT with your story, if you have one!
Our 9 year old: “What can a kid do to get on Santa’s ‘bad’ list ? I mean adults do things that are so much worse than any kid so, like, what could a kid possibly do??’
Congrats to Youssef Ezzyat
@yezzyat
on being named an APS Rising Star!! Youssef began his grad career asking ‘What is an episode in episodic memory?’ and started a whole field of research on events and memory! I would want to know what he’s up to next!! 🤓
Day 1: working home side by side with my 9 and 11 year old children. 9 year old gets quiet and eyes widen, then he says ‘Mom how do you type so fast?’
#coviddiaries
Check out our new paper in
#jneuro
! We find that sleep spindles affect the way memories are represented after sleep, including enhanced hippocampal-cortical functional connectivity and neural integration of memories in vmPFC
@LilaDavachi
I suggest before you ‘study mentorship’ in any setting, you define and verify what mentorship is. You’ve done neither in this paper. What you’ve done is study how ‘co-authorship’ relates to ..
This was a hypothesis Dave formulated when he inquired about a potential postdoc position in the lab. A hypothesis based on a deep knowledge and understanding of how arousal influences cognition applied to new area. Beautiful work Dave!
How does the brain transform continuous experience into memorable episodes? Check out my new preprint w/
@LilaDavachi
suggesting that a surge in arousal at ‘event boundaries’ helps construct memories of discrete events!
@urihoresh
Our culture has more tolerance for lies than for people who freely express their opinions, sentiments and struggles. This is not good. We have the protect freedom of speech, freedom of thought. I feel for the next generations inheriting this world.
Thanks for making this important statement. Yesterday, was reading yet another twitter rant directed at a woman about her statistical practices AND SHE HAD PREREG her experiment and analyses!!! OS bros are acting just like old-school bros! It needs to stop!
Oh twitter. Every time I want to get excited by open science, I see a twitter conversation where OS bros are aggressively accusing someone of bad practice (that someone happens to be a women, pure coincidence right...). Just don't OK?
So excited to share intriguing behavioral evidence that schema memory forms early, decays with time and yet still influences episodic retrieval more when those memories are weaker. The plot thickens...amazing collab with
@AlexaTompary
!
Interested in the relationship between schemas and the episodes that make them up? Check out our new preprint! We find that episodic retrieval relies more on schematic memory over time, even as the schemas themselves become less precisely remembered.
What happens after encoding to all of the myriad experiences from the day? This beautiful work by
@emilytcowan
shows how anterior and posterior hippocampus may sort experiences so that they become more separated in ant hipp and more overlapping in post hipp!
New paper with
@LilaDavachi
out now in Learning & Memory! We found that with consolidation, and potentially sleep in particular, representations in anterior hippocampus become more differentiated but posterior hipp representations become more overlapping.
Tonight my 11 yr old daughter shared with me that she has imaginary friends with her in school to help her get thru the day (they are pixies 🧚♀️ all named after diff colors)
#coviddiaires
Day 2 schooling at home.
beautiful work from a great team
@marchica
and
@yezzyat
. learning over two days instead of one produces more differentiated memory representations in mPFC. Consolidation or temporal context or both? Either way, impt evidence for why spaced learning dominates!
Great new work by
@LilaDavachi
lab! "Differentiation of human medial prefrontal cortex activity underlies long-term resistance to forgetting in memory"
Amazing new paper shows coupled hippocampal and temporal cortical ripples during successful memory retrieval! Beautiful work from Vaz, Inati, Brunel and Zaghloul!
Conscious retrieval versus subliminal reactivation: Which is better? That’s the wrong question— turns out they both change memories but in different ways. Motivated by concepts of retrieval inhibition and associative spread. Super fun and inspiring collab!
Out there!
Happy to tell you about this cool work
@TMR_et_al
and I (co-first) did together with Bruce Caughran,
@kap101
and
@LilaDavachi
about how unconscious reactivations affect memory differently than conscious reactivations!
How are events en/coded by the human hippocampus? Clue 1: Context and sequence position codes emerge in distinct hippocampal subregions. A long and fun collaboration with
@OdedBein
. Let us know what you think!
🚨new paper🚨 with
@LilaDavachi
! CA3 subregion of the hippocampus integrate events based on context, while in parallel, dentate gyrus subregion pattern separates only items close in time and in the same context
@russpoldrack
Yes! I’ve been in for years. Let’s urge conference organizers to adopt a 3 yr plan: Yr 1: meet in person, Yr2: teleconference, Yr 3: local chapters meet (train travel only). Let’s start with SFN? CNS? SfNtweets
@CNSmtg
I am shocked by how many people are spewing anger here in these days following the loss of so much beautiful life. It’s not hard to see how we go from this to that, is it? Maybe it’s time to listen in quiet reflection and spread love instead of more hate?
Congratulations to the 2023 APS Board of Directors election winners! Randi Martin will begin her term as APS President-Elect in June, and will be joined by new APS Board Members-at-Large Teresa Bajo and
@LilaDavachi
as they begin their three-year terms.
Our first deep dive into specific circuits in schizophrenia that are showing dysfunction before medication and then regularize with treatment. Brilliant work by Asieh Zadbood and my amazing collaborators Don Goff and Jijun Wang (and the whole team!!)
How are memories formed? How are they combined to make knowledge?
@LilaDavachi
has been exploring this question of "building blocks of knowledge." You can watch a video here:
And see her at our conference this weekend!
This is absurd, and the original paper. I would say if your task is flawed, you cannot expect the data to be accurate. Work on experimental design please!!
I know that fMRI research has serious replicability problems that need to be addressed, but news headlines like this are deeply harmful to our field, both in terms of public understanding of the work we do and in the way that other neuroscientists see us.
Happiness today? Controlling one of my favorite video games (Galaga) using the EMG recorded from my arms and shooting with eye blinks! Thanks
@BackyardBrains
It’s official! The inimitable
@camillecgasser
was awarded her F31 to examine interactions between motor learning and episodic event memory! Congrats Camille!! 🎊🎉🥰
Here’s to David Clewett and
@sarahdubrow
who both are true scholars. Nice to see their hard work trying to sum up the current data on events, memory and time finally out - thanks
@DavidCRowland
for taking the time to let us know!!!
This from
@LilaDavachi
et al is everything I want from a review. It's really hard to write about dozens of experiments in detail and still hold the audience's attention, but they manage.
@jayvanbavel
Results not replicating are not the same as fabricated data! I feel the article didn’t do a good job of distinguishing these.. Very few ‘scientists’ forge data but many findings may not replicate even tho methods were sound.
Imagine how many lives might have been saved if Trump would have given US citizens access to the level of screening and health care he and his wife are now receiving. Who is ‘elite’ now?
I’ve had the pleasure of recently joining this great department and now we’re hiring again - this time a tenure track position in Developmental Psychology! Please retweet!
I feel like I met my sister from another mother today —-
@Muireann_Irish
teaching my lab about her intriguing and important work on patients with semantic dementia. Thank you and look forward to more discussion!
Had the best time presenting some of our work
@ColumbiaUniver
today and having great discussions with
@LilaDavachi
and her lab! Thanks so much for having me!
Searching for rocks on the beach today our 9 yo says: “mom if you tell me what shape and color and size you want it’s much easier for me to find them.” Discovering basic visual search principles during play.
Who says introspection has no place in science?!!
#proudparent
One of the highlights of quarantine according to our 9 yo is he gets to do big art projects with us. We are in the midst of making an artic wolf habitat diorama! (I may be getting a little *too* into it)
#FridayVibes
the iranian people are so strong and beautiful. the youth (15-30 yo) are leading a revolution right now. they are getting jailed, raped and murdered. but they still rise. the Islamic Republic needs to face the reckoning. Amplify this msg!
#WomenLifeFreedom
Cross-cutting synthesis of predictive processing meets memory representations. The old assumption was that prediction errors improve memory/learning. Like all things, it’s more complicated…
@OdedBein
@camillecgasser
@TarekAmerPhD
@anatmaril1
🚨In press🚨We synthesize neural and behavioral work to ask how predictions and prediction errors lead to memory integration and separation. Super fun collab with this dream team
@camillecgasser
(first co-author)
@TarekAmerPhD
@anatmaril1
@LilaDavachi
!
@rachelxbernard
@PaperWhispers
@smooth357
@YouTooBio
💯 need at least two weeks. It’s common courtesy to appreciate peoples time and work schedules. Plus I don’t write form letters, I put a lot of time, recall specific instances and add details to my letters.
Sooo, my 11 yr old daughter wants me to cut her long hair into a Pixie cut. Today. This makes me more nervous than any talk I’ve ever given. I still remember a hair cut I got at her age that made me cry. Advice?
Finding positive meaning in past negative events adaptively updates memory, leading to enhanced positive emotion and content at future retrieval
@mspeer3
@mr_delgado1
Day 6: My daughter inspired by Master Chef Junior makes me a salad of arugula, mashed avocado, cucumber and apple?! It’s quite delicious!
#coviddiaries
Speaking of voodoo.. every time we submit a ms for review, we make an offering to the gods. If the offer is ‘accepted’, the ms is likely to be invited for full review. It’s worked like a charm since 2004!
@leraboroditsky
Our latest offering
@camillecgasser
Beautiful series of studies manipulating the location and kind of boundary (abrupt vs gradual) shows that in-the-moment subjective duration judgments reflect the duration of the most recent event in working memory. Kudos to
@brynnesherman
@sarahdubrow
!!!!!
Another 4 years later, very excited that this is out in the world! We (
@sarahdubrow
,
@JonWinawer
,
@LilaDavachi
) show that event boundaries -> compressed duration judgments (due to reduced memory access) + hippocampal patterns predict subjective judgments!
Incredible news. Hoping this will bring much needed attention to the awful situation in Iran. The Iranian people need International communities to listen, look and act!
#WomenLifeFreedom
I'm experiencing one of the happiest moments in my life. Awarding Narges Mohammadi the
#NobelPeacePrize
honours her sacrifice and the broader Iranian struggle for fundamental rights.
#WomanLifeFreedom
First paper out from this rich dataset that presents repeated sequential events to examine how the human hippocampus codes object sequences. If you are a journal editor and want this paper to consider - let us know!
Excited to share a new preprint with
@LilaDavachi
! “Event integration and temporal pattern separation: how hierarchical knowledge emerges in hippocampal subfields through learning” 1/n
So much to learn from children. Leafing thru old videos and found this.
Then 4 yr old: you know why i say nothing is my favorite thing?
Me: Why?
Him: ‘cause i love everything.
#wisdom
As shown behaviorally by Morrow, Greenspan and Bower in 1987, we see evidence for representational persistence in visual cortex within but not across event boundaries. Congrats
@yezzyat
!
@SBMost
It all depends on the question no? We have learned a lot from studies with N=12, 17, 20 - mainly studies with elegant experimental design and behavior. Also — Bad design + 1 million subjects still equals bad data. Size is not everything 😂