No evidence for a biological hypothesis of depression; rather the impact of childhood trauma, life stress, and lack of social supports.

Psychiatry's medicalization of social and psychological suffering is not justified by the currently known biology.

Mice exploring a labyrinth freely for the first time learn a complex action sequence after a handful of rewards, exhibiting a learning rate 1000-fold higher than in commonly-used paradigms.

In the STAR*D study, NIMH investigators committed research fraud. The final outcomes paper needs to be retracted.

A knockin mouse line was made to label endogenous AMPA receptors, enabling direct observation of synaptic plasticity in behaving animals with single-synapse resolution across the entire brain.

Nature - A laboratory study unravels ways non-antibiotic drugs can contribute to drug resistance.

Nature - The view of biology often presented to the public is oversimplified and out of date. Scientists must set the record straight, argues a new book.

Dr. Aftab objects to my "tirade against psychiatric neuroscience." What Dr. Aftab does not do is address any of my substantive conclusions.

Nature - Studies find a densely connected network of neurons that communicate over long distances, rather than across synapses.

Decades of failure to identify genes for schizophrenia should put to rest the notion that it is a genetic disorder, E. Fuller Torrey writes.

Chua et al. map the compound eye and the lamina of micro-wasp Megaphragma viggianii in the same specimen with a few-nanometer resolution. The stereotyped cartridge connectome is similar to but...

No evidence for a biological hypothesis of depression; rather the impact of childhood trauma, life stress, and lack of social supports.

Nature - Signals originating in the brain make their way to gut nerve cells, leading to a release of inflammatory chemicals.

Psychiatry’s depression outcomes are poor because its treatments are based on a depression model that science has flushed down the toilet.

Nature - Technique pushes the instruments to beat the resolving power of multi-million-dollar machines.

The STAR*D Study has been cited as real-world evidence of the efficacy of antidepressants. In truth, it told of a failed paradigm of care.

The causes of depression are much more complex than the serotonin hypothesis suggests

In stressful times, this surprising lesson from neuroscience may help to lessen your anxieties.

Nature - Military veterans with cognitive and psychological problems saw drastic improvements after a dose of the potent drug ibogaine.

Former NIMH director Thomas Insel, by hiding results from long-term trials of psychiatric drugs, makes a case for abolishing psychiatry.

Despite new claims of "clear evidence" linking serotonin and depression, their study actually supports the opposite conclusion.

Peter Sterling gives a talk on his book What is Health? to the Cornell University Psychology Colloquium in September 24, 2021. Talk runs about 35 min followe...

Letter to the editor regarding “A Novel, Brief, Fully Automated Intervention to Extend the Antidepressant Effect of a Single Ketamine Infusion: A Randomized Clinical Trial”

Nature - Prairie voles lacking oxytocin receptors bonded with mates and cared for pups.

This cohort study describes mental disorder life histories across 4 decades among participants in the Dunedin Study.

This essay contributes a biologist’s perspective, identifying humanity’s fundamental needs in our necessary transition to a new world order.

New trial challenges current thinking about ketamine The repurposing of ketamine for use in mental disorders is a noteworthy yet disputed development in psychiatry over the past two decades.12...

Ketamine “may actually be ineffective for the short-term treatment of MDD.”