Hani Goodarzi @genophoria Twitter profile

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Hani Goodarzi

@genophoria

2 years

Almost used this expired water for my qPCR! Glad I caught it! Phew!

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Hani Goodarzi

@genophoria

6 years

1/n. The travel ban was upheld by the SCOTUS and as an Iranian American I am devastated by this decision. This imposes a blanket ban, no ifs and no buts. Setting aside what it does to my personal life, it will have a catastrophic impact on the lives of grad students and postdocs.

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Hani Goodarzi

@genophoria

4 years

Muslim ban -> Travel ban -> H1B/J ban -> Student ban

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Hani Goodarzi

@genophoria

3 years

I am deeply grateful to the Vilcek Fdn @Vilcek for this recognition. Immigrants are and have long been the backbone of science and technology in the US. I am surrounded by visionary immigrants, and I am excited to be their representative for today...

The Vilcek Foundation

@Vilcek

3 years

🔬🧬🧪Congratulations to the recipients of the 2022 Vilcek Foundation Prizes in #BiomedicalScience . Vishva M. Dixit - @dixitvishva - receives the Vilcek Prize. @Landry_Lab , @genophoria , and @harriswangnyc receive Vilcek Prizes for Creative Promise.

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Hani Goodarzi

@genophoria

6 years

Joining twitter, my goal was to get exposure to political and scientific discourse. Now, more and more, the scientific questions seem woefully trivial. It's impossible to take a primer on GenBank seriously, when the post above and below outline the ways our society is collapsing.

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Hani Goodarzi

@genophoria

8 months

I am excited to join all the amazing investigators and scientists at @arcinstitute ! Can't wait to do some cool computational and technology-centric team science! And looking forward to joining forces with the innovation and ignite awardees to expand our community!

Arc Institute

@arcinstitute

8 months

We’re thrilled to welcome Hani Goodarzi @genophoria , Associate Professor of Biochemistry & Biophysics @UCSF , as our newest Core Investigator His groundbreaking research uses machine learning models and experimental frameworks to dig into cancer progression and metastasis.

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Hani Goodarzi

@genophoria

3 years

Excited to see this out after such a long time. Debt of gratitude to all the colleagues and collaborators who helped with this over the years: @SohailTavazoie and the lab @RockefellerUniv @hsnajafabadi Claudio @FKHM .

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Hani Goodarzi

@genophoria

2 years

Super excited to see the launch of @exaibio . When @lisacfishsci and I started our search for orphan RNA species (oncRNAs), never did we imagine it will lead us here. Now some of the smartest people I know will be working on this problem! @babak_alipanahi @lisacfishsci

The Vilcek Foundation

@Vilcek

2 years

The Vilcek Foundation congratulates Hani Goodarzi and the team @exaibio on securing $67.5M to finance a new RNA-based platform for early #cancer detection. @genophoria is the recipient of a 2022 #VilcekPrize for Creative Promise in Biomedical Science.

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Hani Goodarzi

@genophoria

6 years

As the incoming graduate students start to pick their rotations, this is my take on what they should consider when they pick a lab: 1. One of the key virtues of academia is that you get to choose who you work with, so take full advantage of that.

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Hani Goodarzi

@genophoria

1 year

Excited to announce Vevo’s launch! What started as coffee chats with @kevansf close to 7 years ago has now given us an opportunity to rethink how we do drug discovery.

Vevo Therapeutics

@vevo_ai

1 year

Vevo Therapeutics has officially launched out of stealth today with an oversubscribed and upsized $12M seed financing. We are so excited to reveal what we have been building behind the scenes! 🧵1/6

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Hani Goodarzi

@genophoria

6 years

I am starting to get harassment emails for my writing/interviews on the impact of travel ban on students... it means it's working, right?

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Hani Goodarzi

@genophoria

5 months

Gathering for our first day at ⁦ @arcinstitute ⁩!

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Hani Goodarzi

@genophoria

6 years

One of the biggest obstacles to interdisciplinary research is that in the end four reviewers are asked to comment on different aspects of the study. The likelihood of four reviewers from different fields being positive about a single manuscript is exceedingly low.

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Hani Goodarzi

@genophoria

2 months

Read our newest preprint to learn about orphan non-coding RNAs (oncRNAs) and how they form blood-readable digital molecular barcodes that capture the identity of cancer cells. A very long 🧵

Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity...

From extrachromosomal DNA to neo-peptides, the broad reprogramming of the cancer genome leads to the emergence of molecules that are specific to the cancer state. We recently described orphan...

www.biorxiv.org

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Hani Goodarzi

@genophoria

6 years

11/n. I plead you to check up on those around you. Make sure they are fine. Tell them it will be alright. Tell them they will see their parents again. Tell them they will see their friends soon. Let's make sure we protect the psyche of these young students. Our 1 job today!

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Hani Goodarzi

@genophoria

4 months

I am late to my own party, but I wanted to write a short 🧵 to put this talk in context. First of all, the @TEDTalks team was amazing; there is so much that goes into these seemingly short talks. It was an amazing experience and I made some new friends.

What if a simple blood test could detect cancer?

Catching cancer at its earliest stages saves lives. But in a body made up of trillions of cells, how do you spot a small group of rogue cancer cells? Biomedical researcher Hani Goodarzi discusses his...

www.ted.com

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Hani Goodarzi

@genophoria

3 years

Thanks to @AACR and @MPMCapital for the support. I am extremely grateful to @AACR for their crucial and continued support over the years.

UCSF Helen Diller Family Comprehensive Cancer Ctr

@UCSFCancer

3 years

Kudos to Hani Goodarzi @genophoria recipient of AACR-MPM Oncology Charitable Foundation Transformative Cancer Research Grant, and thanks to @AACR @UBS @MPMCapital for funding high-risk/high-reward #CancerResearch

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Hani Goodarzi

@genophoria

3 years

Truly inspiring work by my brother-in-law in Joan Steiz's lab. Have known about this for sometime but it still amazes me!

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Hani Goodarzi

@genophoria

10 months

A long time ago, @ElementoLab and I came up with our solution to the gene-set enrichment analysis. We used mutual information to measure the association between gene-set membership and input. After a decade, a talented undergrad spearheaded an update:

Addressing biases in gene-set enrichment analysis: a case study of Alzheimer’s Disease

Inferring the driving regulatory programs from comparative analysis of gene expression data is a cornerstone of systems biology. Many computational frameworks were developed to address this problem,...

www.biorxiv.org

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Hani Goodarzi

@genophoria

1 year

Check out our latest paper in @NatureCellBio exploring the link between alternative polyadenylation, translation efficiency, and metastasis.

Albertas Navickas

@a_navickas

1 year

Links between translation and alternative polyadenylation in metastasis? The story is out today! A great collab between @genophoria , @AndreiGoga_SF and @FKHM labs! Shout out to co-authors @Gentremet , @JulianeScience , @lisacfishsci among others!

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Hani Goodarzi

@genophoria

3 years

Excited to share our second preprint of the week, courtesy of our former lab specialist Bruce Culbertson and our resident specialist Kristle Garcia, with help and support from many others, most notably Josh Rabinowitz’s group!

A sense-antisense RNA interaction promotes breast cancer metastasis via regulation of NQO1 expres...

Antisense RNAs are ubiquitous in human cells, yet the role that they play in healthy and diseased states remains largely unexplored. Here, we developed a computational framework to catalog and...

www.biorxiv.org

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Hani Goodarzi

@genophoria

1 year

Took us a minute, but I am happy to share the final version of this study, now published at @NatureCancer , on behalf of Bruce and Kristle. We have it all, regulatory RNA interactions, oxidative stress/ferroptosis, and metastasis:

A sense-antisense RNA interaction promotes breast cancer metastasis via regulation of NQO1 expres...

Nature Cancer - Culbertson et al. profile antisense RNAs using a newly developed computational pipeline and identify NQO1-AS as contributor to breast cancer progression and lung metastasis through...

www.nature.com

Hani Goodarzi

@genophoria

3 years

Excited to share our second preprint of the week, courtesy of our former lab specialist Bruce Culbertson and our resident specialist Kristle Garcia, with help and support from many others, most notably Josh Rabinowitz’s group!

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Hani Goodarzi

@genophoria

6 years

Our first paper and really great work by Dr. Lisa Fish (a postdoc in my lab) and @at__steven (former HHMI med student fellow) and great collaboration with @AndreiGoga_SF . Below is a thread summarizing our work if you're interested in learning more.

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Hani Goodarzi

@genophoria

5 years

I echo the voices of other Iranians(-Americans) here. Again, discriminating against an entire nation based on poorly conceived notions of security. Both human health and science are borderless...

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Hani Goodarzi

@genophoria

8 months

Genomic interval tools, like bedtools and bedops, have formed the backbone of our analytical pipelines for many years now. @noamteyssier has now developed a new package called 'gia' that is order of magnitude faster! Check out our preprint and take gia for a spin.

Noam Teyssier

@noamteyssier

8 months

I'm very excited to release this project I've been working on for about a year or so now! gia is a high-performance genome interval arithmetic toolkit, written in #rustlang 🦀, with significant performance increases (2x-20x) over #bedtools and #bedops .

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Hani Goodarzi

@genophoria

2 years

Does anyone keep track of how many international students, postdocs, and scholars are waiting for their (re)entry visas in the US? It seems like a sort of things us academics should pay more attention to.

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Hani Goodarzi

@genophoria

1 year

Am I the only one who says "please" to ChatGPT? I certainly hope not!

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Hani Goodarzi

@genophoria

4 years

In the mist of everything that is happening, I wanted to take a moment and highlight our most recent paper (thread): RBMS1 suppresses colon cancer metastasis through targeted stabilization of its mRNA regulon.

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Hani Goodarzi

@genophoria

6 years

An opinion I wrote for The Scientist. Please help disseminate this and if you have ideas and platforms that could help deal with this crisis, please DM me.

Opinion: Broken Promises Caused by the Travel Ban

The scientific community must step up to support students and scholars who will undoubtedly face isolation.

www.the-scientist.com

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Hani Goodarzi

@genophoria

2 months

I have been thinking about the best approaches for building predictive models in liquid biopsies for many years now! Orion, which was built by the @exaibio team with input from our advisors @ElementoLab and @james_y_zou is the culmination of that effort.

Deep generative AI models analyzing circulating orphan non-coding RNAs enable accurate detection of...

Liquid biopsies have the potential to revolutionize cancer care through non-invasive early detection of tumors, when the disease can be more effectively managed and cured. Developing a robust liquid...

www.medrxiv.org

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Hani Goodarzi

@genophoria

5 months

A great start to 2024! Thank you for the shoutout @EricTopol . You said it all!

Eric Topol

@EricTopol

5 months

How do you go from 9 million molecules to 8 which appear effective against a micro RNA driver of breast cancer? Like this @Patterns_CP #AI @genophoria @UCSF @UCSFCancer

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Hani Goodarzi

@genophoria

6 years

4/n. I did not leave the US for the entirety of grad school (+1 year), until I became a permanent resident. During this time, I saw my parents exactly 0 times. I missed countless birthdays and weddings. I lost multiple relatives without getting to say goodbye.

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Hani Goodarzi

@genophoria

4 years

Congratulations @KivancBirsoy ! An inspirational journey... Go middle-easterners!

Kivanç Birsoy - Vilcek Foundation

Creative Promise Prizewinner Kıvanç Birsoy, born in Turkey, develops cutting-edge tools to unravel the metabolism of cancer cells and targets for treatment.

vilcek.org

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Hani Goodarzi

@genophoria

2 years

May have overestimated how many assays I can run over the weekend!

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Hani Goodarzi

@genophoria

1 year

Y'all, check out our latest preprint on determinants of small RNA release. We used machine learning to show much of the information is encoded in the primary RNA sequence and can be leveraged to predict which small RNAs are effectively secreted. See this thread from @BaharZirak

Bahar

@BaharZirak

1 year

Super excited to share the results of our highly collaborative project co-led by @MNaghipourfar , Ali Saberi, @DelaramPB , Amirhossein Zarezadeh and supervised by my incredible mentor @genophoria .

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Hani Goodarzi

@genophoria

2 months

Check out this new preprint/white paper from our friends at Entwine bio together with @vram142 and @ZaroLab . We and others have long been interested in sequence-to-function modeling in RNA, especially as it comes to splicing.

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Hani Goodarzi

@genophoria

5 years

I am reviving this thread to announce the final publication of this preprint. Almost a full year after the preprint was first submitted! A clear example of how biorxiv expedites dissemination of science.

Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay

Fish et al. show that TARBP2-mediated recruitment of the methyltransferase complex and the subsequent deposition of m6A marks on TARBP2-bound transcripts result in intron retention, leading to...

www.cell.com

Hani Goodarzi

@genophoria

6 years

Our first preprint, in which we describe a regulatory function for nuclear TARBP2. Comments & suggestions are welcome.

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Hani Goodarzi

@genophoria

10 months

I came to this country 15 years ago, and it is unbelievable to me that we haven't managed to improve this system even an iota in these years. It is not just a cruel system, it is also self-defeating. Please read this thread and tag your senators. @AlexPadilla4CA @SenFeinstein

Masoud

@linguistMasoud

10 months

I’m quite used to the cruelty students can face when they apply for a US visa but this one broke me. We offered admission to a stellar, talented & hardworking student. After months of work and hundreds of dollars, an embassy officer saw him for 5 mins & said no. why? …

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Hani Goodarzi

@genophoria

6 years

7/n. But even now the scars are there... almost every Iranian student I have talked to shares a common nightmare: you suddenly wake up in Iran and you have no idea what you are doing there, how you got there, where your documents are, and how you can get back.

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Hani Goodarzi

@genophoria

6 years

8/n. This universal nightmare binds us all. It is too late for my generation... we hollowed out our relationships and drastically reshaped our lives for a higher calling. I have personally achieved the goals set by younger self, but there r days that I wonder if it was worth it.

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Hani Goodarzi

@genophoria

4 years

I'm super happy that the UCSF magazine has covered this story. @FaranakFattahi 's work is nothing short of inspirational. Cracking the Coronavirus Gender Mystery

COVID-19 Frontliners: Cracking the Coronavirus Gender Mystery

Why are more men than women dying of COVID-19? Scientist Faranak Fattahi, PhD, has found a clue.

magazine.ucsf.edu

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Hani Goodarzi

@genophoria

3 years

The first time I really thought about RNA was when I read the major transitions in evolution, and I have been hooked ever since. Happy #RNAday !

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Hani Goodarzi

@genophoria

1 year

3300 subjects across 8 cancers; overall stage I sensitivity of 87% at 95% specificity in the held-out test set. 88% tissue-of-origin accuracy! Watching the @exaibio team do their magic has truly been a privilege.

exai bio

@exaibio

1 year

Exai announced compelling new data at #ASCO23 , demonstrating strong performance in stage I detection of multiple cancers including breast and prostate cancers, overcoming early-stage detection limitations of other blood-based approaches.

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Hani Goodarzi

@genophoria

4 months

Thank you for having us @arcinstitute !

Arc Institute

@arcinstitute

4 months

☀️It’s a great week at Arc as we welcome our new Core Investigator @genophoria and his lab, and our first Science Fellow @zhou_jingtian ! We’re proud to add these talented minds to our ranks, bringing with them a multidisciplinary approach to human disease research. Welcome, all!

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Hani Goodarzi

@genophoria

1 year

Another movement from @khorms57 's magnum opus in our lab. A rigorous attempt at systematically annotating functional RNA structural switches that show conformation-dependent regulatory functions 👇

Matvei Khoroshkin

@khorms57

1 year

RNA folding affects gene expression, but this link is not well explored in Eukaryotes. We researched RNA structural switches and discovered hundreds of them in the human transcriptome. We even visualized some of their 3D folds with CryoEM. Thread below:

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Hani Goodarzi

@genophoria

6 years

5/n. My mom went through a cancer scare without me by her side (I am a single child). Given the visa restrictions and the expenses, it was difficult if not impossible for my parents to visit either (and they never did).

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Hani Goodarzi

@genophoria

3 years

Hey y’all, check out our latest preprint and this fantastic Tweetorial from our senior postdoc @a_navickas ! h/t @a_navickas @Gentremet @lisacfishsci @AndreiGoga_SF @JulianeScience @FKHM

Albertas Navickas

@a_navickas

3 years

Excited to share the latest results from the @genophoria lab & a great collaboration with @AndreiGoga_SF and @FKHM labs! Shout out to the amazing co-authors @Gentremet , @JulianeScience , @lisacfishsci and many more!

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Hani Goodarzi

@genophoria

6 years

10/n. People showing up to airports to protest, and lawyers gathering to help was nothing short of miraculous. However, as we have moved on to other daily outrages, and there is no shortage of them, we risk leaving behind students and scholars who are devastated by this decision.

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Hani Goodarzi

@genophoria

4 years

Can someone please just come over and knock me out for the day... I really wanna miss the next 24hr. Please and thank you!

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Hani Goodarzi

@genophoria

4 years

Trump had requested ~20% cuts to NIH year after year! You can’t will scientific progress into existence... it needs sustained prioritization and investment! Let’s not forget that when this is all over...

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Hani Goodarzi

@genophoria

6 years

8. PhD mentors are for life. They will always be your mentor and your best advocate. My advisors are still my go to guys when I have to make tough decisions. And I believe you ask them for letters till the end of time.

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Hani Goodarzi

@genophoria

6 years

6/n. Both my parents and my in-laws and countless friends missed our wedding. I took this emotional isolation in stride and in some sense I even got used to it. By the time restrictions were lifted, I had been isolated for years. Years have passed...

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Hani Goodarzi

@genophoria

9 months

Check out this beautiful in vivo perturb-seq study from @LukeGilbertSF , @LabRaleigh , and Bill Weiss at @arcinstitute and @UCSFCancer !

bioRxiv

@biorxivpreprint

9 months

In vivo perturb-seq of cancer and immune cells dissects oncologic drivers and therapy response #bioRxiv

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Hani Goodarzi

@genophoria

2 years

We started this #RNAyear by saying goodbye to two longtime amazing postdocs: @a_navickas who is off to Institut Curie to start his own "RNA in cancer" lab! And @MKarimzade who is joining @exaibio to build ML models for disease detection. Certainly a bittersweet moment for our lab

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Hani Goodarzi

@genophoria

6 years

Our first preprint, in which we describe a regulatory function for nuclear TARBP2. Comments & suggestions are welcome.

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Hani Goodarzi

@genophoria

6 years

9/n. I say all this not because I think you don't agree that this is bad policy. When we started the "academics against the travel ban" (), we collected close to 50k signatures in a short span of time. It was both heartwarming and reassuring.

The Petition - No To Immigration Ban

President Donald Trump has signed an Executive Order (EO) proposing a 90-day suspension of visas and other immigration benefits to all

notoimmigrationban.com

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Hani Goodarzi

@genophoria

4 years

We attempted the whole online class thing for our systems biology course. Turned out better than expected! #scRNAseq @mattjonesucsf

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Hani Goodarzi

@genophoria

4 years

Please take a few minutes out of your busy day and read our preprint with the @FaranakFattahi lab. Hi-quality in vitro drug screen, supplemented by in silico GCNN screens, followed by targeted validation and clinical confirmation.

Faranak Fattahi

@FaranakFattahi

4 years

Our preprint on COVID-19: •Antiandrogenic drugs reduce ACE2 •higher free androgen predicts poor outcomes in men Is this why men are more affected & kids are protected? Big thanks to @genophoria @UCSF , @xaniarg @YaleIMed , @pnatarajanmd @MassGeneralNews

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Hani Goodarzi

@genophoria

1 year

Super exciting news! I am happy that our oncRNAs are living their best lives at @exaibio ! I am also excited for this strong commitment to breast cancer. Breast tumors don't shed a lot of DNA and DNA-based tests show poor performance at low burdens. OncRNAs will change that...

exai bio

@exaibio

1 year

Based on initial positive data, Exai is proud to announce expanded participation in the I-SPY 2 Trial to advance our novel RNA-based liquid biopsy platform for breast cancer. ’s-Novel-RNA-based-Liquid-Biopsy-Platform-in-Breast-Cancer

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Hani Goodarzi

@genophoria

3 years

Shout out to @sinabooeshaghi for showing up to our systems biology class (via zoom) and giving one of the best presentations of the whole course! Also I’m told he has some exciting stuff brewing... so, follow him and stay tuned!

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Hani Goodarzi

@genophoria

4 years

Check out our short review of machine learning efforts focused on SARS-COV-2. Already old given how fast these efforts have expanded.

Artificial Intelligence for COVID-19 Drug Discovery and Vaccine Development

SARS-COV-2 has roused the scientific community with a call to action to combat the growing pandemic. At the time of this writing, there are as yet no novel antiviral agents or approved vaccines...

www.frontiersin.org

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Hani Goodarzi

@genophoria

4 years

I am devastated by this news. She was a fantastic mentor... so kind and generous with her time and resources. A great loss for us at UCSF and the entire cancer research community. She will be missed.

Fernando Martin-Belmonte

@Fernand49142950

4 years

Zena Werb Today we have lost one of UCSF’s most beloved faculty. Zena Werb died suddenly this morning. A member and VC of the Department of Anatomy, for almost 40 years, Zena was an outstanding scientist. She was one of the world’s leading experts on ECM on cancer development

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Hani Goodarzi

@genophoria

7 years

Estimate RNA stability changes from RNA-seq alone. Inspired work by @hsnajafabadi ! Excited to have been part of it.

Inference of RNA decay rate from transcriptional profiling highlights the regulatory programs of...

Nature Communications - “mRNA abundance is determined by the rates of transcription and decay. Here, the authors propose a method for estimating the rate of differential mRNA decay from...

www.nature.com

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Hani Goodarzi

@genophoria

6 years

2/n. A bit of background. I was born in Iran. My visa application for grad school, for which I had to travel twice to Turkey, took close to 4 months to process. I had a single-entry visa, which was valid only for 3 months, meaning when I entered the US, I couldn't leave again.

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Hani Goodarzi

@genophoria

3 years

My resolution for 2021 is to lose weight by getting a haircut! The way vaccinations are going, this may become my 2022 resolution!

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Hani Goodarzi

@genophoria

6 years

3/n. I came to the US in 2006 under NSEERS (what is now known as muslim registry). I was questioned once before getting on the plane to Newark and once after. We were checked up on regularly by agents who would show up regularly on campus.

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Hani Goodarzi

@genophoria

4 months

Folks about to graduate with bioinformatics/data science backgrounds who are interested in research, please apply:

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Hani Goodarzi

@genophoria

12 days

The Bioinformatics team led by Alex Dobin within the Computational Technology Center at the Arc Institute is seeking a Senior Scientist. Come join us and tackle some of the most fundamental problems in the intersection of biology and computation.

Senior Scientist, Bioinformatics, Computational Technology Center

Palo Alto, CA

boards.greenhouse.io

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Hani Goodarzi

@genophoria

6 years

A nice piece describing our latest paper. Super excited about this...

UC San Francisco

@UCSF

6 years

UCSF researchers discover new kind of RNA molecule that drives the spread of breast cancer. The discovery may one day lead to non-invasive cancer diagnostics.

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Hani Goodarzi

@genophoria

2 years

@dsboothacosta Funding for grad students (stipend+tuition+research) should be separated from our grants and be b/w the program & students. Then students can join the labs that best suit them, vs just well-funded labs. It also clarifies our roles as mentors/advisers & not bosses.

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Hani Goodarzi

@genophoria

1 year

Please check out our latest preprint, together with @FKHM , and @halfacrocodile , along with a detailed Tweetorial from Matvei. Learn about post-transcriptional regulatory modules and how we went about identifying them:

Systematic Identification of Post-Transcriptional Regulatory Modules

In our cells, a limited number of RNA binding proteins (RBPs) are responsible for all aspects of RNA metabolism across the entire transcriptome. To accomplish this, RBPs form regulatory units that...

www.biorxiv.org

Matvei Khoroshkin

@khorms57

1 year

Can’t wait to share the splendid results of the collaboration between the incredible labs of @genophoria , @FKHM , and @halfacrocodile ! Tl;dr: we've explored the code on how RNA-binding proteins team up to regulate their target RNAs. Read on for more! (1/15)

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Hani Goodarzi

@genophoria

2 years

It was a lot of fun talking to Frontier Science about my thoughts on multidisciplinary research at the intersection of computational and experimental biology, our work in this space, and our path towards translation.

BIOS

@bios_community

2 years

Frontier Science 🧫 - Modeling Oncological Systems 🧬 w/ Hani Goodarzi - Associate Professor @UCSF Learn more about Goodarzi's ( @genophoria ) work & the below...

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Hani Goodarzi

@genophoria

4 years

Grateful to be working with these amazing postdocs. From right, Dr Heather Karner, Dr Sahar Tavakoli, Dr Hossein Asfharian, and Dr Albertas Navickas. Missing a few of our postdocs today.

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Hani Goodarzi

@genophoria

4 years

For all the RNA peeps out there attending #RNA2020 online. If you are interested in the role of regulatory RNA structural elements in RNA splicing and disease, please check out my talk (15). Happy to answer questions here or any other platform.

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Hani Goodarzi

@genophoria

6 years

4. 5 yrs is a long time... don't think you can just work through it if there are concerns. 5. Don't join a lab to learn a technique; join a lab to learn the fundamentals of how good science is done.

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Hani Goodarzi

@genophoria

2 years

The number of emails I send daily has been growing exponentially... and I have noticed that I am writing shorter emails, often devoid of pleasantries (the PI syndrome!). I think we need a GPT-3 plugin that makes our emails more polite and courteous.

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Hani Goodarzi

@genophoria

5 years

I just came back from my 4th study section and I wanted to share some thoughts. I have served 2x on BDMA (computational) and 2x on MGB (experimental). These are my thoughts from this small n (thread) 👇

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Hani Goodarzi

@genophoria

3 years

Late better than never! We celebrated PAW with our amazing postdocs working on site. With @a_navickas & Heather who basically run the lab, and welcoming Benedict and Siyu who just joined recently. Looking forward to next year and all the awesome science they are doing!

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Hani Goodarzi

@genophoria

5 years

Celebrating another year with our awesome postdocs. My life would be insanely more difficult without them! From right: Drs. Fish, Navickas, Asgharian, Baygi. #ucsfNPAW #ucsfpostdocs #NPAW #NPAW2019

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Hani Goodarzi

@genophoria

2 years

Had loads of fun with @AndreiGoga_SF , @girlsinscience_ , and the UCSF BOP family at the Tri-Valley SOCKs breast cancer walk yesterday! Sad we said goodbye to this event! #breastcancer #SteppingOutforCancerKures

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Hani Goodarzi

@genophoria

6 years

This is my first election as a US citizen... Come on America, don't let me down 🤞

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Hani Goodarzi

@genophoria

5 years

Early access to a perspective by Peter Walter and @MullinsLab "From Symbiont to Parasite: Evolution of For-Profit Science Publishing". p7: "what remains puzzling is the lack of more widespread anger in our communities regarding the degree of exploitation"

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Hani Goodarzi

@genophoria

2 years

Had a blast in Bergen! Come for the views, stay for the science. Thank you @Halberglab1 for the invite. Really, A gem of a place! Extra points for the pride celebration!

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Hani Goodarzi

@genophoria

2 years

Check out this tour de force from the Fattahi lab! It has it all… platform building, basic biology, drug screening, functional validations…

Faranak Fattahi

@FaranakFattahi

2 years

We made enteric ganglioids from hPSCs, showed they’re similar to human ENS, used them to find neuromodulators that regulate GI motility and demonstrated their engraftment potential in mouse colon. Check out our new preprint by @homamajd et. al.

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Hani Goodarzi

@genophoria

2 years

I know success is not linear, but that trampoline is the best definition of “privilege” if there ever was one!

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Hani Goodarzi

@genophoria

3 years

As our NextGen grant for transformative cancer research comes to an end, I had an interview with @AACR on the impact of this grant on our research. Spoiler alert: we may have not transformed cancer res, but certainly tried... and the night is still young.

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Hani Goodarzi

@genophoria

4 years

@s_tavazoie @PNASNews I found this sketch from 10 years ago when @s_tavazoie first told me about (a version of) this idea! Few in this day and age show this level of stick-to-itiveness! Congratulations Panos and the @s_tavazoie lab.

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Hani Goodarzi

@genophoria

5 years

Dear tweeps, We are looking for postdocs in RNA biology, genomics, cancer biology, and computational biology. Please help spread the word.

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Hani Goodarzi

@genophoria

5 years

Super excited to see @FaranakFattahi on this list...showing the rest of us how it's done! Also happy to see the strong showing by @UCSF . Congratulations to all the awardees.

NIH Common Fund

@NIH_CommonFund

5 years

The @NIHDirector ’s New Innovator award supports early career researchers. Meet the 2019 awardees. #NIHHighRisk

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Hani Goodarzi

@genophoria

5 years

This morning, I've written and deleted multiple tweets b/c they fail to convey the depth of my frustration! It's one of those weeks that needs an entire book to rant. I'm just so disappointed in everyone and all things! I could use a pep talk from my idealistic 20yr old self.

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Hani Goodarzi

@genophoria

4 years

I’m sitting here in a hot and loud server room, nursing a badly degraded zpool. How is your thanksgiving going?

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Hani Goodarzi

@genophoria

6 years

9. Talk to everyone in the lab. If you can, find those who have left. Learn to read between the lines. But also, understand that it takes two to tango. Someone's heaven can be another's hell.

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Hani Goodarzi

@genophoria

2 years

@eperlste This reminds me of a story... a friend of ours was asked, a long time ago, how he saw the brain drain problem in Iran; he wisely said: "it can't be that bad, because I am still here"!

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Hani Goodarzi

@genophoria

2 years

Really amazing work by @mpassarelli15 and the @SohailTavazoie lab! tRNAs continue to amaze! Congratulations @mpassarelli15 :) It was a ton of fun to work on this together.

Maria Passarelli, MD, PhD

@mpassarelli15

2 years

Very excited to share our paper, identifying a tumor-suppressive tRNA synthetase, published today in @naturecellbiol ! @sohailtavazoie @genophoria @triimdphd @rockefelleruniv … 1/11

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Hani Goodarzi

@genophoria

7 months

Come join us at @arcinstitute !

Arc Institute

@arcinstitute

8 months

Core Investigators are pivotal to Arc’s mission – they’re scientific leaders who are empowered to tackle curiosity driven research. Today, we’re proud to announce a new call for applications in partnership with @StanfordDBDS .

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Hani Goodarzi

@genophoria

2 years

Come join us on the sunny side of SF! We promise excellent mentorship, cool science and technology, and ever-flowing coffee (and Covid-permitting Friday lab lunches)!

Vijay Ramani

@vram142

2 years

Please RT! Seeking RAs to support computational & molecular projects in our lab, including collabs with the inimitable @genophoria =). A great opp. for recent grads looking for postbac experience. Links below:

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Hani Goodarzi

@genophoria

3 months

Check out our review on the regulatory pathways of translational control that are hijacked by cancer cells. The credit largely goes to @schen_sc and @a_navickas for putting this together over the holidays!

Siyu Chen

@schen_sc

3 months

Thrilled to share our latest review on translational adaptation in breast cancer metastasis and the promising therapeutic opportunities it unveils! Immense thanks to @genophoria and @a_navickas !

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Hani Goodarzi

@genophoria

1 year

Between GPT-4 and Midjourny-5, I am hit hard by technology envy. Like, how did I spend 4 decades of my life without access to these tools? Last time I felt this way was when smart phones arrived.

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Hani Goodarzi

@genophoria

6 years

2. There aren't universally good/bad PIs; like any other relationship, chemistry matters and it goes both ways. 3. The culture of the lab is really important; make sure you are in a healthy drama-free environment.

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Hani Goodarzi

@genophoria

6 years

6. Don't try to join a lab because the science is popular. Chances are by the time you're done, everyone has moved on to the next big thing.

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