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CZI Science Profile
CZI Science

@cziscience

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573
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5,388
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Supporting the science and technology that will make it possible to cure, prevent, or manage all disease by the end of the century.

SF Bay Area
Joined June 2017
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@cziscience
CZI Science
4 months
From #SingleCell to cell-based therapies, we’re building capacity for AI applications to cell biology at scale. @chanzuckerberg ’s Head of Science @StephenQuake shares our vision for using AI to help scientists advance our understanding of cell + systems biology
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@cziscience
CZI Science
2 years
This live video of intestinal tissue taken by Gustavo Meneze shows the wave-like muscle contractions that move food through the digestive tract 🔵 blood vessels 🔴+ 🟢 immune cells #ImagingTheFuture
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@cziscience
CZI Science
3 years
Watch 📹 @ChanZuckerberg is pushing the frontiers of imaging to help researchers everywhere visualize life's processes and understand how they contribute to health and disease
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@cziscience
CZI Science
5 years
Open source software is 🔑 to science. Many of the packages, libraries + applications crucial to biomedicine are built by researchers who volunteer their time + effort to make these tools available. We’re excited to announce support for #opensource tools
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@cziscience
CZI Science
4 years
#Opensource software is essential to science—that’s why we’re supporting 42 open source tools that accelerate biomedical research and serve the larger community. Learn about the grantees
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@cziscience
CZI Science
3 years
Increasing access to bioimaging worldwide will help advance biomedical research and improve health outcomes. Our new RFA aims to expand access to imaging expertise, technologies + capacity building #ImagingTheFuture
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@cziscience
CZI Science
7 months
We’re thrilled to share that we’re launching a new @CZBiohub in New York! Bringing together engineers + scientists at @Columbia , @RockefellerUniv and @Yale , #CZBiohubNY will engineer immune cells for earlier detection & treatment of disease
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@cziscience
CZI Science
2 years
Science should be by and for everyone. In partnership with @theNASEM , we’re excited to welcome 25 Science Diversity Leadership grantees who are diversifying biomedicine through research + mentorship 🙌🏽🙌🏿🙌🏾
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@cziscience
CZI Science
4 years
A T-cell (green) attacks a cancer cell (blue). Our new RFA aims to support imaging #tech so researchers can watch cell dynamics in real time. 📹 by Alex Ritter using an Andor Revolution spinning disk system with an Olympus microscope
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@cziscience
CZI Science
2 years
We’re excited to announce that the @ChanZuckerberg Institute for Advanced Biomedical Imaging’s initial focus will be to identify and map the position of every protein in a cell. Learn more from our co-founder’s exclusive @Medscape interview:
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@cziscience
CZI Science
4 years
#Opensource software is essential to science. That’s why we’re awarding 23 grants to support open source tools that accelerate biomedical research and serve the larger scientific community.
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@cziscience
CZI Science
1 month
Using spatial and #SingleCell transcriptomics, a @nature publication from @StephenQuake & Thomas Sudhof’s teams unravels the cellular + molecular architecture of long-term memory consolidation
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@cziscience
CZI Science
6 years
Today we announced funding for 85 one-year projects that will focus on developing an open set of computational tools, algorithms, visualization methods and benchmark datasets for scientists working on the @humancellatlas . Learn more about the projects:
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@cziscience
CZI Science
3 years
Our new internationally-focused RFA will fund imaging cores and network organizations from select countries that bring together imaging scientists to collaborate and share expertise. Learn more ⤵ #ImagingTheFuture
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@cziscience
CZI Science
3 years
🚨 #OpenSource tools are the invisible foundation of biomedicine. That’s why we’re continuing to support open source software projects essential for scientists. Learn more about our grantees
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@cziscience
CZI Science
2 years
We’re excited to announce that David Agard, Bridget Carragher + Clint Potter have joined our new @ChanZuckerberg Imaging Institute to bring together scientists and engineers to develop new cryoelectron microscopy imaging hardware and software 🧵
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@cziscience
CZI Science
3 years
🚨 New funding alert 🚨 Imaging core facilities and network organizations from Latin America, the Caribbean, Africa + former Soviet countries are invited to apply to @ChanZuckerberg ’s RFA to support increased global access to bioimaging #ImagingTheFuture
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@cziscience
CZI Science
2 years
Grantees are recognized for their track record of supporting #DiversityinSTEM + their mentorship of the next generation of biomedical researchers. Learn about their projects ⤵️
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@cziscience
CZI Science
3 years
. @Caltech chemical engineer Mikhail Shapiro is creating the first acoustic biomolecules allowing ultrasound to image how specific cells function deep inside the body. This work will be transformative for neuroscience, immunology, cancer biology and more #ImagingTheFuture
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@cziscience
CZI Science
2 years
#ScienceAsArt 🎨 This mesmerizing display of color, captured using lattice light-sheet imaging, shows the dynamic movement of macrophage immune cells during a 3-minute timelapse. 📹 by CZI Imaging Scientist @DrNickCondon of @IMBatUQ #ImagingTheFuture
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@cziscience
CZI Science
2 years
🎥 Watch as these 3D intestine organoids grow from single stem cells in a dish. @priscaliberali is #ImagingTheFuture by building #OpenSource tools for imaging + analysis with @napari_imaging
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@cziscience
CZI Science
4 years
Good news: @UCSF is now offering free #COVID19 testing to nine Bay Area counties in partnership with @ChanZuckerberg , @CZBiohub and @CAgovernor
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@cziscience
CZI Science
2 years
💻 We’re releasing the CZ Software Mentions Dataset—a dataset of 67M software mentions mined from biomedical literature—to understand how widely research software + open source tools are used across disciplines. Explore the dataset ⤵️ #TechForTheFuture
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@cziscience
CZI Science
1 year
🟪= mitochondria 🟦= cell nucleus 🟩= mitochondrial DNA Many diseases, including hearing loss, are caused by damage to mitochondria and mitochondrial DNA. Imaging Scientist Uri Manor studies how damage to mtDNA is communicated to the cell body + the nucleus #ImagingTheFuture
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@cziscience
CZI Science
5 years
Collaboration drives progress in #science . Our new Seed Networks grants bring together 200+ scientists, engineers, and physicians to contribute to the @humancellatlas ! Learn more: #HumanCellAtlas
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@cziscience
CZI Science
6 years
Very excited to see the first @humancellatlas datasets made openly available. Congratulations to everyone who contributed to this effort!
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@cziscience
CZI Science
2 years
Did you know? There are hundreds of datasets and 29M+ cells on #CZCellxGene to help accelerate #SingleCell research: Learn more 🧵
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@cziscience
CZI Science
2 years
🎥 Watch as these 3D intestine organoids grow from single stem cells in a dish. @priscaliberali is #ImagingTheFuture by building #OpenSource tools for imaging + analysis with @napari_imaging
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@cziscience
CZI Science
5 years
Microscopy—critical to biomedicine—generates large volumes of complex data that pose significant computational challenges. We’re excited to announce funding for open-source software efforts to improve image analysis and visualization:
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@cziscience
CZI Science
5 years
We’re excited to share that @Meta , a free research discovery tool, is now available. Meta provides a faster way to understand, organize, and explore science through personalized feeds. Researchers can now sign up for a free account
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@cziscience
CZI Science
3 years
Claire Brown mentors the next generation of imaging scientists and has helped build research & training networks like @BioimagingNA , @GlobalBioImage and @CanBioImage #ImagingTheFuture #CellBiology 📹 : Cell migration and division by Claire M. Brown, @mcgillu
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@cziscience
CZI Science
3 years
🗣 Immigrants are critical to science.
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@cziscience
CZI Science
8 months
🚨Funding opportunity 🚨 The Essential #OpenSource Software for Science program supports maintenance, growth, development + community engagement for critical tools used by biomedical scientists globally
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@cziscience
CZI Science
4 years
We’re excited to announce 30 grantees to our #RareAsOne Network. These patient-led organizations are partnering with clinicians and researchers to accelerate research for their #RareDisease
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@cziscience
CZI Science
1 year
We’re thrilled to welcome our Science Diversity Leadership grantees to CZI HQ! Over three days, scientists led panels + gave talks on how their labs are accelerating research across biomedicine #DiversityInSTEM
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@cziscience
CZI Science
3 years
We’re excited to welcome researchers and pediatricians who are studying childhood health + disease. Congratulations to @ChanZuckerberg ’s Pediatric Networks for the @humancellatlas grantees! Learn more about their projects
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@cziscience
CZI Science
4 years
We’re welcoming 60 new grantees to @ChanZuckerberg ’s Neurodegeneration Challenge Network! These researchers are piloting innovative approaches to fighting neurodegenerative diseases like #Alzheimers , #Parkinsons + #ALS
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@cziscience
CZI Science
5 years
We require our grantees to: 💻Deposit software code to a repository such as @github 📝Submit results to preprint servers like @biorxivpreprint 🔬Make experimental protocols accessible via sites like @protocolsIO Read about our support of open science:
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@cziscience
CZI Science
1 year
“Trainees need mentorship, both technically and for career development, to ensure work from the lab progresses and that they fulfill their career aspirations.” - @IshmailSaboor , researcher at @ZuckermanBrain
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@cziscience
CZI Science
3 years
🔊 We’re excited to support 14 new projects developing imaging #tech , and launch a new funding opportunity for software engineers to create plugins for @napari_imaging #ImagingTheFuture
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@cziscience
CZI Science
5 years
There are no effective ways to cure, prevent or treat most neurodegenerative diseases like #Alzheimers , #Parkinsons and #ALS . Our new RFA aims to help change that
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@cziscience
CZI Science
10 months
Did you know? #CZCellxGene has the largest repository of standardized #SingleCell data from 45M unique cells across tissues, including the: 👁️ Retina 🧠 Brain 🫁 Lungs 🫀 Heart + more Discover something new:
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@cziscience
CZI Science
3 years
New imaging grants will 💻 Increase access to imaging expertise + #tech 🔗 Foster collaborations between imaging scientists + researchers 🌍 Increase representation of regional imaging scientists in the global community Apply #ImagingTheFuture
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@cziscience
CZI Science
6 years
We require our grantees to publish detailed methods on a site like @ProtocolsIO , ensuring the best protocols are available to all scientists. This saves time, money, and—most importantly—helps science move faster. We’re proud to support @ProtocolsIO :
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@cziscience
CZI Science
7 months
Meet the 18 new teams diving deep into the mechanisms of metabolism, featuring projects exploring spatial mapping, metabolic networks + metabolite biosensors
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@cziscience
CZI Science
3 months
We’re excited to support 64 interdisciplinary teams that are taking innovative approaches to study fundamental #neuroscience + neurodegenerative diseases. Read more about our second cycle of @ChanZuckerberg ’s Neuroscience Collaborative Pairs Pilot Projects
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@cziscience
CZI Science
5 years
Microscopy—critical to biomedicine—generates large amounts of complex data for scientists to visualize and analyze. Today we announced funding for CZI Imaging Scientists, who will help biologists leverage modern technology for microscopy data.
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@cziscience
CZI Science
8 months
We are planning to build a high-performance computing cluster with 1000+ GPUs to accelerate AI for biomedical science, including advancing the development of new virtual cell 👇🪡
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@cziscience
CZI Science
5 years
Priscilla Chan and @karliekloss present the #BreakthroughPrize Life Sciences award to Dr. Virginia Man-Yee Lee of @Penn for inventing a protein roadmap to neurodegenerative disorders and elucidating common mechanisms of degeneration in diseases like #Parkinsons + #ALS
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@cziscience
CZI Science
5 years
Great news for open science: The number of downloads from @biorxivpreprint has topped 1 million per month (via @nature ):
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@cziscience
CZI Science
1 year
Grantee @channyskye of @EvansLab describes her mentoring style as building relationships where trainees cultivate: 🔬research confidence 🥼a STEM identity 🤔critical thinking skills What’s your mentoring style? #MentoringMonth
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@cziscience
CZI Science
5 years
Today we’re announcing funding for @iamalsorg , a patient-led organization dedicated to raising awareness of #ALS and empowering patients to lead the search for a cure
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@cziscience
CZI Science
6 years
We’re excited to announce our new Imaging Scientists Request for Applications! This program aims to accelerate biomedicine by improving microscopy tools and facilitating better collaboration between biologists and technology experts.
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@cziscience
CZI Science
1 year
We’re excited to announce that we’re scaling the @CZBiohub & launching a new Biohub in Chicago! #CZBiohubCHI will build new tech to precisely measure biological processes in human tissues in real time and at unprecedented resolution🧵👇🏻
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@cziscience
CZI Science
8 months
Exciting news! #CZCellxGene now has 50M+ unique cells + 915 datasets, providing an even more reference-quality #SingleCell data for you to download & visually explore. Thanks to all the researchers who have contributed their data to cellxgene!
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@cziscience
CZI Science
6 years
Congratulations to Dr. Sarah Teichmann -- co-leader of the @humancellatlas & Head of Cellular Genetics @sangerinstitute  -- for being featured as one of 30 women leaders in UK healthcare. Great to see women like Sarah leading the way in #STEM .
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@cziscience
CZI Science
5 years
The majority of rare diseases are not well understood + less than 5% have approved treatments. The #RareAsOne Project will connect communities of patients, researchers + clinicians to work together to find cures #RareDisease
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@cziscience
CZI Science
1 year
“Diverse teams—where all voices are respected—challenge each other in important ways that drive research forward.” -Grantee @IshmailSaboor , a researcher studying pain at @ZuckermanBrain #NationalMentoringMonth
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@cziscience
CZI Science
3 months
We’re excited to welcome new imaging grantees! 9 new Deep Tissue Imaging projects will drive development of imaging technology focused on obtaining cellular resolution readouts within complex living organisms. Learn about the projects
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@cziscience
CZI Science
2 years
“Increasing diversity in science will identify novel genetic variations affecting cellular function, empowering studies to discover new biological insights.” @AleMedinaRivera hopes studies of populations in Mexico will help to understand the higher rates of lupus
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@cziscience
CZI Science
4 years
Collaboration is 🔑 to fighting #RareDisease . @yaya4HL founder Ron Garber knew he could accomplish more if he combined efforts with other affected families along with researchers and clinicians #RareAsOne
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@cziscience
CZI Science
3 years
🚨Funding opportunity 🚨 We’re excited to announce a fourth cycle for our Essential #OpenSource Software for Science RFA, which funds software projects that support the computational foundations of biomedical science 👩🏽‍💻👨🏻‍🔬 🧵
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@cziscience
CZI Science
3 years
“Future advances in imaging technology will require highly interdisciplinary collaborations, combining hardware, computational methods and molecular tools.” -Chemist and @ChanZuckerberg Deep Tissue Imaging grantee Claire Deo #ImagingTheFuture
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@cziscience
CZI Science
1 year
This is fat tissue under a microscope 🔬 Notice how the small blood vessels 🔴 go all throughout the fat cells 🔵, ready to deliver immune cells 🟢 where needed 📷 Gustavo Menezes @bioimagingbr #ImagingTheFuture
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@cziscience
CZI Science
1 year
The precisely coordinated cell movements of the early embryo are key to how organisms form different tissues. Here are some of those movements in all their glory, captured in a 12-hour timelapse of a zebrafish embryo by @czbiohub ’s @loicaroyer + @Merlin_Lange #ImagingTheFuture
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@cziscience
CZI Science
5 years
We’re excited to launch the #RareAsOne request for applications—providing up to 10 #RareDisease patient orgs with funding, training, tools + mentorship. Learn more and apply:
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@cziscience
CZI Science
4 years
This morning, hundreds of people came together in Times Square to put a face to neurodegenerative diseases and stand for their loved ones fighting for #CuresForAll . We are proud to stand with them.
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@cziscience
CZI Science
6 years
"The Chan Zuckerberg Initiative is just starting, and we have a lot to learn. But I’ve been lucky to work in areas in which the free exchange of ideas and results is the norm. In my experience, such an approach creates the most dynamic fields." @betenoire1
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@cziscience
CZI Science
5 months
📢Calling all #SingleCell researchers Visualize gene expression using the largest integrated resource of over 50 million unique cells #CellxGene ⬇️
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@cziscience
CZI Science
3 years
We’re joining the rare disease community worldwide and illuminating CZI’s office for #RareDiseaseDay . #ShowYourStripes
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@cziscience
CZI Science
2 years
“We are interested in describing the mutations + molecular characteristics associated with types of cancer that are important in Mexico & other Latin American countries.” #RareDisease Acral melanoma is understudied in Mexico. @daniela_oaks is changing that #LatinxHeritageMonth
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@cziscience
CZI Science
6 months
As part of our work in #neuroscience + #neurodegeneration , we are committed to supporting early career researchers across disciplines & expertise. Meet our second cohort of Ben Barres Early Career Acceleration Awards grantees ⤵️
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@cziscience
CZI Science
1 year
We hosted a workshop on accelerating #OpenScience in Latin America to enhance participation + collaboration in computational biomedicine and open research 🌎💻 #CZILatAmMtg
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@cziscience
CZI Science
4 years
#OpenSource software is the future of science. Thanks to everyone who joined us for our meeting on the challenges and progress of open source in accelerating research #EOSSmtg
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@cziscience
CZI Science
4 years
We believe in the importance of rewarding the creators of the often invisible but critical computational infrastructure for science. Read about what we learned from the first cycle of our Essential #OpenSource #Software for Science RFA
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@cziscience
CZI Science
5 years
“Knowing more about inflammation will increase our understanding of many diseases and improve our ability to cure, prevent or manage them.” — @JCoolScience Read 👇
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@cziscience
CZI Science
1 year
CZI Imaging Scientist Leonel Malacrida ( @MalacridaLab ) is developing an advanced bioimaging facility in Uruguay to provide state-of-the art #tech for all researchers in the country & train the next generation of scientists in modern imaging and analysis methods #ImagingTheFuture
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@cziscience
CZI Science
6 years
“We need to stay close to the scientists and their needs if we’re going to accelerate science.” @betenoire1 at the #AAASmtg in Austin.
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@cziscience
CZI Science
1 year
“Having leaders from diverse backgrounds creates environments where there are shared personal and academic experiences between advisors and trainees. This, in turn, leads to more impactful mentoring experiences.” -Grantee @ArmstrongFlyLab
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@cziscience
CZI Science
6 years
Neurodegenerative diseases are a leading cause of disability and death worldwide. We seek to support a stronger scientific understanding of neurodegeneration and will soon invite applications to join our Neurodegeneration Challenge Network. Details here:
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@cziscience
CZI Science
2 years
🎉 Thrilled to share our new imaging grantees! We’re supporting 41 projects to develop + maintain plugins on #OpenSource tool @napari_imaging , and 17 global imaging groups increasing access to imaging #tech + fostering collaboration #ImagingTheFuture
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@cziscience
CZI Science
5 years
Thank you to everyone who attended the @ChanZuckerberg Seed Networks for the @humancellatlas meeting! We can’t wait to see where your projects lead #HumanCellAtlas
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@cziscience
CZI Science
6 months
This week, our #SingleCell biology grantees gathered to share their research, connect with other research groups + discuss how they can use new data & technologies to understand health & disease. Attendees, what was your favorite part of the meeting?
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@cziscience
CZI Science
6 years
We are now accepting applications for our Seed Networks RFA! Watch the video to learn about the RFA and our approach to collaborative science:
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@cziscience
CZI Science
2 months
Join us in welcoming @USCDornsife ’s Scott Fraser to our team as VP of Science Grant Programs 🥳 Bridging chemistry, engineering + physics to unravel the complexities of biology, he knows the power of innovation & collaboration in science. We’re excited to have him on board
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@cziscience
CZI Science
5 months
Join us in celebrating the launch of the Seattle Hub for Synthetic Biology with @AllenInstitute + @UWMedicine . 🎉 Led by @JShendure , this new collaboration will build tech to understand temporal dynamics of cells & whole organism perturbation ➡️ #SeaSynBio
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@cziscience
CZI Science
5 years
Computational skills are 🔑 for scientists to fully leverage their data. We’re partnering with @MooreFound to support @thecarpentries to teach programming and data science skills to researchers worldwide #bioinformatics
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@cziscience
CZI Science
5 years
“You know, you’re 37. You see a whole life in front of you and now all of a sudden that life may not exist.” - @bsw5020 . Read how #RareDisease warrior Brian Wallach founded @iamalsorg to change the future for his family and others with #ALS
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@cziscience
CZI Science
4 years
There are no effective therapies for diseases like #Alzheimers , #Parkinsons + #ALS . We need to support early career researchers to bring new ideas and approaches to solving neurodegenerative disorders
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@cziscience
CZI Science
4 years
Mothers Liz Berger and Beth Buccini started @ddx3x Foundation to make a difference in their daughters’ lives and other children affected by DDX3X. Read about their work to find a cure for this #RareDisease #RareAsOne
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@cziscience
CZI Science
6 years
Thank you to everyone who made the CZI Computational Tools for the @humancellatlas meeting such a success. It was an exciting demonstration of the power of open cross-institutional scientific collaboration. Here’s to the year ahead!
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@cziscience
CZI Science
4 years
We’re launching a new COVID-19 task force with @CZBiohub , @UCSF and @Stanford to increase collaboration and better respond to the coronavirus outbreak in the Bay Area
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@cziscience
CZI Science
10 months
Thank you to everyone who joined us this week! We can’t wait to see you next year 🔬 #ImagingTheFuture
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@cziscience
CZI Science
2 years
“Latin America has great potential and is commonly overlooked in research; there are amazing groups worth collaborating with.” @AleMedinaRivera 's research centers on diseases like lupus + Parkinson's with a strong focus on including Mexican participants #LatinxHeritageMonth
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@cziscience
CZI Science
7 years
We are excited to announce 38 grants to help advance work on the @humancellatlas ! Details here:
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@cziscience
CZI Science
3 years
Meet Brian Wallach ( @bsw5020 ), who is living with #ALS . He co-founded @iamalsorg and is searching for cures to save his life and the lives of others living with #RareDisease #CuresForAll
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