Ran Blekhman Profile Banner
Ran Blekhman Profile
Ran Blekhman

@blekhman

6,682
Followers
538
Following
1,237
Media
9,863
Statuses

Assoc Professor at @UChicago / Human genomics & microbiome research / Opinions my own (he/him) /

Chicago
Joined November 2012
Don't wanna be here? Send us removal request.
Pinned Tweet
@blekhman
Ran Blekhman
1 year
Mother’s milk is a critical, dynamic biological system We show that maternal genetics controls milk gene expression and composition, which in turn shape the infant gut microbiome Our latest, led by @kelsey_EJ , great collab w/ @frankwalbert @DemerathE
Tweet media one
7
100
455
@blekhman
Ran Blekhman
5 years
Congratulations, you invented taxes and public education
@nytimes
The New York Times
5 years
Silicon Valley is backing a novel idea: Instead of charging students tuition, students go to school for free and are required to pay back a percentage of their income after graduation, but only if they get a job with a good salary
744
2K
5K
75
5K
16K
@blekhman
Ran Blekhman
3 years
Elon Musk
@Abebab
Abeba Birhane
3 years
What's something that seems scientific but isn't?
819
56
726
55
2K
15K
@blekhman
Ran Blekhman
4 years
Do US citizens understand how stressful it is to be an immigrant scientist in the US? Far from family/friends, never ending visa bureaucracy & payments, constant fear of not being allowed back in the US, or being forced to leave your home/job/PhD due to some ban
297
3K
12K
@blekhman
Ran Blekhman
4 years
As a professor at a public university, my job is 60% research, 20% teaching, 20% service, 20% paperwork, 20% grant writing, 20% mentoring, 10% reviewing, 5% organizing, and 5% letter writing, so there's really not a lot of time for radical left indoctrination
128
1K
9K
@blekhman
Ran Blekhman
4 years
Stuck at home with small kids due to #COVID19 ? Here are some fun activities you can enjoy together: - Write a research paper - Teach a class via zoom - Write a grant proposal - Email
95
916
9K
@blekhman
Ran Blekhman
3 years
My biologist origin story is that when I was a young child I found out I was fascinated by grant applications
53
472
7K
@blekhman
Ran Blekhman
3 years
reading about people taking ivermectin for covid and the stories are really heartworming
110
731
6K
@blekhman
Ran Blekhman
2 years
telling students in my class about the history of genomics
Tweet media one
83
354
4K
@blekhman
Ran Blekhman
4 years
Just got an email that one of my grants got an automatic 1 year no-cost extension, without even requesting it, due to #COVID19 Grant admins and funding agencies: this is a great way to support your investigators during this crisis
18
280
3K
@blekhman
Ran Blekhman
4 years
Basically how machine learning works
@Rainmaker1973
Massimo
4 years
The story of Nigel Richards, the man from New Zealand who memorized every French word in the French scrabble dictionary and won the French Scrabble Championship without speaking any French
Tweet media one
173
3K
12K
18
441
2K
@blekhman
Ran Blekhman
7 years
There's no cure for polio. There's a highly effective vaccine. This vaccine, by the way, was developed by a son of immigrants.
@GovMikeHuckabee
Gov. Mike Huckabee
7 years
Take on 4 big diseases that cost the BULK of $$: Cancer, heart disease, Alzheimers, diabetes; find CURES like we did with polio in 50's.
1K
351
1K
42
1K
2K
@blekhman
Ran Blekhman
3 years
I am not an expert in epidemiology or virology, have never researched vaccination strategies, and find immunology uninterpretable, but here is my thoughts on whether we should delay the 2nd vaccine dose (1/79)
36
163
2K
@blekhman
Ran Blekhman
4 years
If you are annoyed by being called a trainee as a PhD student, wait till you're a professor and still called "early career" in your 40s
40
74
2K
@blekhman
Ran Blekhman
3 years
Just did the calculation: my household has saved $4,932 by not paying for parking on campus over the last 18 months The university parking system -- making employees pay large amounts to park at work -- is a scam, plain and simple
45
120
2K
@blekhman
Ran Blekhman
4 years
Not to mention a constant uphill battle to advance your career. You think writing papers or giving talks is hard? Try doing it in a different language. Oh, and you're ineligible for most fellowships and funding opportunities
13
200
2K
@blekhman
Ran Blekhman
3 years
Why does every computer science professor have a webpage that looks like it was built in 1995 by writing HTML from scratch?
83
61
2K
@blekhman
Ran Blekhman
1 year
Breakdown of PhD student cost on a grant: tuition $45K stipend $35K fringe $10K indirects $60K -- total paid by NIH to university: $150K total paid by university to student: $35K (this is just a toy example to illustrate a point, not real numbers but same ballpark)
54
212
2K
@blekhman
Ran Blekhman
4 years
The first 90% of a paper takes 90% of the work. The remaining 10% of a paper accounts for the other 90% of the work.
12
137
1K
@blekhman
Ran Blekhman
1 year
New proposed postdoc salary scale in the Boston area, based on data from a salary and benefits survey
Tweet media one
84
219
1K
@blekhman
Ran Blekhman
4 years
Work from home update -- Number of papers I've read: 0 Number of times I've watched Frozen 2: 137
13
72
1K
@blekhman
Ran Blekhman
3 years
Imagine a job where once you're hired your boss says "welcome! Now go do whatever you want. We'll check back in 5 years, and then either fire you or give you the job for life"
21
60
1K
@blekhman
Ran Blekhman
4 years
Received dozens of replies that say "go back to your country, free up your job for Americans" If I go, I take my lab with me. This not only won't free up jobs, but would actually take away several job opportunities for Americans. (Also I'm not going anywhere)
@theodore_beza
Theodore Beza
4 years
@blekhman Time to relieve your stress. Return to your country of origin. Use your skills to help develop your own country. There you will live close to your family and within your traditions and culture. Especially during this time of high unemployment, we need those jobs for Americans.
18
0
1
45
119
1K
@blekhman
Ran Blekhman
4 years
As a reviewer, my goal is to find critical flaws, not to "improve" the paper. Every paper can be improved in 100 different ways, many of them subjective. The authors have already decided they're happy with the paper as is. A reviewer is not a co-author or a collaborator.
26
185
1K
@blekhman
Ran Blekhman
4 years
Strong move by University of Minnesota President. This is the type of leadership we need - I support @JoanGabel .
Tweet media one
12
212
1K
@blekhman
Ran Blekhman
3 years
A gentle reminder that graduate students who are immigrants/international are ineligible for the GRFP -- just like they're excluded from almost all other graduate and postdoc fellowships in the US.
11
160
1K
@blekhman
Ran Blekhman
3 years
Mind blowing. The FTO gene is associated with obesity in humans. Plants don't have a homolog. What happens when you transgenically express the human FTO in plants? Giant potatoes and rice
17
258
1K
@blekhman
Ran Blekhman
3 years
Both of these can be true: 1. Grad students and postdocs are underpaid 2. Faculty are underpaid Instead of fighting each other, faculty and trainees should work together to raise salaries in academia
19
125
1K
@blekhman
Ran Blekhman
3 years
Incoming PhD students: joining a new PI's lab as their first graduate student could be one of your best career choices. Lots of 1:1 mentoring, seeing how a lab is built first hand, tons of other advantages. The opposite of a red flag.
@RogersLabUCD
𝘿𝙧. 𝘾𝙧𝙮𝙨𝙩𝙖𝙡 𝙍𝙤𝙜𝙚𝙧𝙨 ≽(◕ ᴗ ◕)≼ 🐥🐸
3 years
Imposter syndrome is hitting hard this morning. I recently found out that graduate students have been told by more established PIs that I am a “red flag” because I have not yet secured external funding and because I haven’t recruited other graduate students. 1/
334
249
5K
22
103
1K
@blekhman
Ran Blekhman
3 years
In my experience a CNS is required for a faculty position, so far I haven't seen anyone hired without a central nervous system
19
69
1K
@blekhman
Ran Blekhman
3 years
It sucks not being able to visit your family Just ask immigrant scientists who haven't seen their family in years because of visa issues & costs, and the very real possibility they would not be allowed back in the country It's time to fix the US visa system
6
114
1K
@blekhman
Ran Blekhman
3 years
Instead of saying "they got covid despite of being vaccinated", say "they got covid with only mild/no symptoms thanks to being vaccinated" 👍
4
153
1K
@blekhman
Ran Blekhman
3 years
If you ever read a paper and get to a part where you ask yourself "why is this part even here? Seems unrelated to the rest of the paper" the answer is almost always "because a reviewer asked for it"
14
51
1K
@blekhman
Ran Blekhman
2 months
Weird getting an email with a $10K bill for a journal publication fee, followed by an email requesting to review a paper for the same journal for free. Feels like being a victim in some kind of a pyramid scheme
21
122
982
@blekhman
Ran Blekhman
7 years
RT if you went to a public school and was never attacked by a bear #DeVosHearing
26
917
838
@blekhman
Ran Blekhman
4 years
#FireFauci implies the existence of an Earth Fauci and a Wind Fauci
20
108
854
@blekhman
Ran Blekhman
4 years
Kamala Harris's mother immigrated from India to pursue a PhD & stayed to work as a cancer researcher Kamala Harris's father immigrated from Jamaica to pursue a PhD & stayed to work as a professor Not sure if they would have been able to do this under the current administration
8
133
854
@blekhman
Ran Blekhman
3 years
Is it just me? When I complete a task and realize it was not on my to-do list, I add it to the list so I can immediately check it off.
41
17
841
@blekhman
Ran Blekhman
3 years
There's a confusion, seems that Pence was referring to a different company, Pfizer Total Landscaping
@GeoffRBennett
Geoff Bennett
3 years
As Pence claims credit, Pfizer says it did NOT join in the administration's partnership. Pfizer head of vaccine development Dr. Kathrin Jansen told the NY Times: “We were never part of the Warp Speed ... We have never taken any money from the U.S. government, or from anyone.”
2K
24K
62K
8
155
814
@blekhman
Ran Blekhman
2 years
📢Big news: my lab is moving to @UChicago ! I'm thrilled to join the superb genomics and microbiome research community at UChicago, and beyond excited about new research directions and collaborations! And we're recruiting at all levels! 👇
Tweet media one
Tweet media two
Tweet media three
Tweet media four
79
99
805
@blekhman
Ran Blekhman
1 year
Research labs at UChicago tonight
Tweet media one
10
42
758
@blekhman
Ran Blekhman
6 years
I can't even read a paper every 5 days
@EricTopol
Eric Topol
6 years
Publish a paper every 5 days?! Profile of the 9000 hyper-prolific researchers @NatureNews by John Ioannidis @METRICStanford @StanfordMed R Klavans K Boyack #OA
Tweet media one
Tweet media two
Tweet media three
28
373
553
12
146
678
@blekhman
Ran Blekhman
2 years
About 50% of my lab's collaborative papers started from discussions in in-person conferences So far we have 0 new collaborations that started in a virtual conference Not saying virtual meetings don't have advantages, but for driving collaborative science, in-person >>> virtual
20
51
669
@blekhman
Ran Blekhman
3 years
Wow -- faculty are 25 times more likely to have a parent with a PhD. Almost 50 times more likely in "prestigious universities"
@aaronclauset
@aaronclauset.bsky.social
3 years
1/ New preprint! The “Socioeconomic Roots of Academic Faculty,” with @alliecmorgan @laberge_nick @DanLarremore Mirta Galesic: We surveyed 7000 U.S. faculty from 8 disciplines to study how socioeconomic status shapes the academic workforce. 🪴 A summary:
Tweet media one
111
2K
4K
23
154
640
@blekhman
Ran Blekhman
3 years
Really appreciate editors who, when sending you back the reviews for your paper, also include a summary of critical points to address -- and more importantly, points you _don't_ have to address, despite what reviewer 3 says
18
38
641
@blekhman
Ran Blekhman
6 years
If there is a single advice I can give to grad students it will be this: Back up your computer. Every file. At least daily. In multiple locations. One of which is off-site or in the cloud.
19
143
624
@blekhman
Ran Blekhman
4 years
Dear reviewers: please stop asking for RNA-seq data to be confirmed with qRT-PCR If the RNA-seq experiment is well-designed w/enough replicates and depth, the qPCR results wouldn't matter. And if the RNA-seq experiment is not well-designed, the qPCR results wouldn't matter
@0_minyaaa
闵娅 (Min Ya | Minya), PhD
4 years
Oops, being asked to confirm #RNAseq results with #qRT -PCR again by a reviewer. Although I have, um (check notes), EIGHT biological replicates per developmental stage. 😬
22
19
391
8
142
627
@blekhman
Ran Blekhman
4 years
Transitioning between scientific fields is challenging but twitter just did a seamless transition from epidemiology to explosives research
5
73
595
@blekhman
Ran Blekhman
2 years
As a scientist, the best thing to hear from a colleague is "we discussed your paper in journal club and everyone liked it". Makes my day every time
3
18
595
@blekhman
Ran Blekhman
3 years
An example of how useful twitter can be as a tool for scientists: After posting a postdoc ad here 4 days ago I've seen thousands of people visiting our lab website (100x more than usual) from all over the world. I did not post an ad anywhere else.
Tweet media one
4
45
584
@blekhman
Ran Blekhman
3 years
16 years ago I moved to the U.S. to start grad school. Today I became a citizen 🇺🇸
Tweet media one
36
4
585
@blekhman
Ran Blekhman
4 years
Wow, how did you get all of them in one zoom call
@weatherdak
Dakota Smith
4 years
Every Atlantic hurricane since 2017.
20
243
982
4
57
572
@blekhman
Ran Blekhman
3 years
This proves my hypothesis that not _everyone_ has imposter syndrome
Tweet media one
7
15
574
@blekhman
Ran Blekhman
4 years
This is taking off so on a serious note, a request: if you are evaluating colleagues for tenure/ promotion in the coming year, please be kind and mindful of this weird situation we are all living through
8
31
558
@blekhman
Ran Blekhman
2 years
how it started, how it's going
Tweet media one
14
4
540
@blekhman
Ran Blekhman
6 years
To the reporters looking for comments on the space twin study: 1. There's no study, just a press release. 2. Changes are in RNA levels, not DNA (unless he came back as a different species) 3. Is this 7% difference a lot? No - literally everything causes changes in RNA levels
11
195
496
@blekhman
Ran Blekhman
4 years
this street though
Tweet media one
8
27
496
@blekhman
Ran Blekhman
4 years
Types of peer review: 1) 3 anonymous scientists write secret reviews in a process that takes a few months 2) dozens of known experts write comments that anyone in the world can see hours after a paper is posted (e.g this thread 👇) Explain to me again why is 1 >> 2?
@trvrb
Trevor Bedford
4 years
Based on the content of my mentions, I feel like I need to further debunk crazy #nCoV2019 / HIV conspiracy preprint. This is a thread doing so. 1/9
62
689
1K
24
107
490
@blekhman
Ran Blekhman
2 years
You think professors are scatterbrained or have a bad memory? Ask them about their grad school rejections from 30 years ago
11
23
486
@blekhman
Ran Blekhman
2 years
Analysis of DNA methylation across 580 (!) animal species
Tweet media one
8
126
468
@blekhman
Ran Blekhman
3 years
If you were a professor of virology when the pandemic started, by now you either have 100,000 followers or you deleted your account
10
8
456
@blekhman
Ran Blekhman
3 years
These are the most common questions about scientists?? I'll try to answer: no no no no no no no no no yes
Tweet media one
4
60
450
@blekhman
Ran Blekhman
3 years
Something that's almost never discussed here, and maybe should be: the experiences of trainees when the PI moves to another institution or leaves academia.
50
32
451
@blekhman
Ran Blekhman
2 months
"How did this get past the reviewers??" I am again asking that we stop blaming reviewers for bad papers. Reviewers spend time & effort with no compensation, and their suggestions are often overlooked. The people responsible are those who actually wrote the paper -- the authors
50
28
449
@blekhman
Ran Blekhman
6 years
Say you pick 100 random bioinformatics software tools -- how many will you actually be able to access, install, and run? Our new paper:
@serghei_mangul
Serghei Mangul #UkraineWillWin 🇺🇦🇲🇩🇺🇸
6 years
1/5 Our preprint about software crisis in computational biology is live! We have performed a review of usability and archival stability of published omics tools and resources. We have found that 28% of the tools are impossible to install.
Tweet media one
23
337
465
19
287
427
@blekhman
Ran Blekhman
7 months
Unpopular opinion (?): universities, scientific societies, and journals don't need to have a position or comment on geopolitical events All they should do is offer support to those impacted, and allow their members to express their opinions without fear of retaliation
12
28
403
@blekhman
Ran Blekhman
2 years
"We are drowning in information, while starving for wisdom. The world henceforth will be run by synthesizers, people able to put together the right information at the right time, think critically about it, and make important choices wisely." - E. O. Wilson
2
79
404
@blekhman
Ran Blekhman
2 years
Yes -- give every PhD a green card! This is exactly what the U.S needs to do to be competitive again for international scientists
@karinfischer
Karin Fischer
2 years
The America COMPETES Act would exempt STEM PhD graduates from green-card caps, effectively stapling a green card to the doctoral diploma of every international student in STEM. It also would charge these applicants an extra fee to fund scholarships for U.S. STEM students 2/
4
19
145
4
37
405
@blekhman
Ran Blekhman
3 years
Just checked the twitter bylaws and it is indeed required that a "CNS paper for faculty position" discussion is always followed by a "working on weekends" discussion
14
17
391
@blekhman
Ran Blekhman
7 years
OK, this is going too far
Tweet media one
10
215
381
@blekhman
Ran Blekhman
4 years
4
42
366
@blekhman
Ran Blekhman
2 years
I don’t get the concern about scientists moving to industry. 1. Having more career options is good for everyone! 2. It’s not like there’s a shortage of brilliant scientists who want a career in academia
21
24
372
@blekhman
Ran Blekhman
3 years
Every BioRxiv preprint includes a warning that it "has not been certified by peer review", but PNAS contributed papers have no disclaimer? How about "This paper has been through a fake peer review process to achieve the illusion of validity; skepticism is advised"
6
47
367
@blekhman
Ran Blekhman
2 years
Thinking about all the international/immigrant scientists who haven't seen their family in years and had to cancel travel plans yet again this year. Such a discouraging situation.
9
29
366
@blekhman
Ran Blekhman
6 years
Looking at the full range of GRE scores --> no correlation between GRE and graduate outcomes
Tweet media one
Tweet media two
Tweet media three
9
205
352
@blekhman
Ran Blekhman
4 years
Definitely happy that I finally caved in and got TSA precheck in November 2019 in anticipation for all the upcoming travel in 2020
16
9
351
@blekhman
Ran Blekhman
6 years
Can we agree on this: if you think NSF is wasteful you should stop using things that were created using NSF funding. Like the internet.
@RandPaul
Rand Paul
6 years
1. On page 207. 2000+ pages to go! Reading about the ever wasteful $6 billion National Science Foundation.
1K
4K
10K
6
137
344
@blekhman
Ran Blekhman
4 years
Impressive new results on COVID19 showing that 28% of the population are susceptible to trusting numbers reported in a tweet with no citation or link
11
36
337
@blekhman
Ran Blekhman
4 years
A question I hear a lot is "what does a normal day of being a prof feels like?" This video perfectly answers it:
@profbof
Simon Clavet
4 years
@_Quazi_ @anorangeduck (3/5) After a day of training, he can withstand significant perturbations (but sometimes you just get too many cubes in the face…):
17
99
552
7
80
338
@blekhman
Ran Blekhman
5 years
Dear editor, we have addressed reviewer 2's concerns and have revised figure 1 as requested
@marklisseman
Mark Lisseman
5 years
Is that diagram… accurate??
Tweet media one
8K
58K
222K
6
56
334
@blekhman
Ran Blekhman
3 years
📣Postdoc positions available in my lab! Research at the interface of microbiome + human genomics. Exciting projects and collaborations, wonderful place to live, lots of flexibility (remote work ok) Informal inquiries welcome - email/DM me. Please RT!
Tweet media one
Tweet media two
Tweet media three
7
273
325
@blekhman
Ran Blekhman
3 years
FYI, all immigrants to the US are *required* to have these vaccines: Mumps Measles Rubella Polio Tetanus and diphtheria Pertussis Haemophilus influenzae type B (Hib) Hepatitis A Hepatitis B Rotavirus Meningococcal disease Varicella Pneumococcal disease Seasonal influenza
14
61
331
@blekhman
Ran Blekhman
3 years
How heritable is the gut microbiome? What influences its heritability? Our latest, where we answer these questions using >16,000 microbiome profiles from wild baboons Work by @ferocious_sloth , wonderful collab with @ArchieLab @jtung5 @AmboseliBaboons
11
94
329
@blekhman
Ran Blekhman
4 months
In -omics studies, understudied genes are systematically abandoned in favor of better-studied genes in the paper writing stage
Tweet media one
6
99
329
@blekhman
Ran Blekhman
4 years
So far, the only concrete steps by the federal government to fight COVID: 1) ban H1B and J1 visas 2) do less testing 3) cancel a funded NIH grant for bat coronavirus research Did I miss anything?
19
50
328
@blekhman
Ran Blekhman
3 months
Mother's milk is often the sole source of nutrition for the baby. Milk also contains diverse bacterial communities -- but how to these bacteria impact the infant gut microbiome? Our latest:
Tweet media one
6
78
321
@blekhman
Ran Blekhman
3 years
We keep hearing that it's critical to take a long break after grad school So this is a gentle reminder that many can't do this, either because they don't have the financial ability to not work, or they're immigrant scientists whose legal visa status relies on employment
5
21
317
@blekhman
Ran Blekhman
3 years
Cool new paper with associations between gut microbes and specific dietary components Top associated foods: 1. Coffee 2. Unsalted nuts 3. Dark chocolate
Tweet media one
10
92
315
@blekhman
Ran Blekhman
3 years
Very strange -- ordered some shrink-wrapped dead cats as usual, but instead got a bunch of conical tubes??? WTF
6
2
312
@blekhman
Ran Blekhman
3 years
Unpopular opinion: graphical abstracts are great! A good graphical abstract can be the most useful visual in a paper
19
7
310
@blekhman
Ran Blekhman
3 years
Confession: I don't really care about the origin of covid and whether or not it's a "lab leak" We should shift the discussion to the U.S fumbled response that lead to 600,000 dead and how we avoid this in future pandemics, which are definitely coming -- lab leak or otherwise
15
32
305
@blekhman
Ran Blekhman
2 years
Comparing preprints to their final published versions: - 93% of articles do not change their main conclusions - only 1 out of 184 published papers contradicted a conclusion made by its preprint
5
92
301
@blekhman
Ran Blekhman
5 years
Famous senior dude at a fancy university: "I don't know why you young folks are complaining about funding, when I started as PI the first 5 grant proposals I wrote were all funded on first try" Me:
9
26
302
@blekhman
Ran Blekhman
4 years
profs emailing “sorry for the late reply” to each other
2
37
303
@blekhman
Ran Blekhman
2 years
I've heard academics complain about almost everything imaginable, but I've never heard anyone complain that a talk was too short
13
14
301
@blekhman
Ran Blekhman
4 years
Of course universities are happy to give tenure clock extension -- they get another year of highly productive junior faculty at much lower salary. Another option is to have it on time, with promotion & tenure committees adjusting their expectations.
6
42
302
@blekhman
Ran Blekhman
5 years
back up your computer
@eliistender10
Giles Paley-Phillips
5 years
Your best advice in 4 words or less
21K
1K
7K
3
46
294
@blekhman
Ran Blekhman
7 months
I've said it before, but a major issue with the current peer review system is that reviewers think their goal is to "improve" a paper that has no critical flaws and can be published as is
@blekhman
Ran Blekhman
4 years
As a reviewer, my goal is to find critical flaws, not to "improve" the paper. Every paper can be improved in 100 different ways, many of them subjective. The authors have already decided they're happy with the paper as is. A reviewer is not a co-author or a collaborator.
26
185
1K
11
47
291
@blekhman
Ran Blekhman
3 years
Reminded of advice I received as a junior PI: Them: Just write a strong grant proposal and it will be funded! Me: But my proposals are not funded Them: That means they're not strong enough! Me: How can I tell that a proposal is strong enough? Them: Because it will be funded!
12
17
290