Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate a wonderful piece of work, congrats
@AChakrabortyPhD
and to everyone involved! Also see accompanying paper from Sonia Rocha!
V excited for labs latest!! Also labs first preprint!!! Great work by all our collaborators and the dude
@parkersulkowski
. Hope you enjoy this unexpected finding and looking forward to feedback!!
Hello
#sciencetwitter
#metabolism
world! We are sad to see Sam McBrayer leave the Kaelin lab but he will be starting his own group at
@CRI_UTSW
!! See below as he is looking for a tech and lab manager! Please share!
Kaelin lab has decided to start studying temperature sensing with its 1st annual summer trip to the only hot pepper farm in New England. From here on out it’ll be all things capsaicin. It got real hot.
Benjamin Lampson, MD, PhD, presented his work on germline ATM variance in chronic lymphocytic
#leukemia
to better understand why patients develop this disease. Results conclude that 1 in 4
#CLL
patients have a geramline variance
#ASH19
Abstract link:
Excited 2 share this editorial written w/
#GregWyant
@kaelin_lab
in Circulation
@CircAHA
! Tryptophan (Trp) is an essential amino acid & an important metabolite. Metabolized 2 serotonin or knurenine (Kyn) pathways and appreciated for its role in CNS (1/4)
Congratulations to the newly elected members of the American Academy of Arts & Sciences! Today we are honored to welcome 276 scholars, leaders, artists, and innovators into the Academy.
Happy to see
@kendyjco
's paper on mitochondrial signaling to mTORC1 online. New data on ETC inhibitors in this version!
Genome-wide CRISPR screens reveal multitiered mechanisms through which mTORC1 senses mitochondrial dysfunction
Check out the first publication from the Oser laboratory in Science Advances! Great collaboration with the
@kaelin_lab
! Congratulations to my post-doc Leslie Duplaquet and my good friend and colleague Sagar Koduri on their beautiful work.
Matthew Vander Heiden, MIT professor of biology and a pioneer in the field of cancer cell metabolism, has been named the next director of MIT’s Koch Institute for Integrative Cancer Research.
So great to put this out! Many years in the making. We used
#CRISPR
screens to find
#mTORC1
regulators and clarified how
#mitochondria
"talk" to mTORC1.