James Hardiman @hardimanjames Twitter profile

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James Hardiman

@hardimanjames

8 months

Deep Tech VC: Puts on pot of coffee to read 5th nature paper for the evening while trying to discern 5yr trajectory of an entire scientific field B2B Enterprise VC: YOLOs into 3 month old genAI company at $100m pre that doesn’t even have product yet We are not the same

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James Hardiman

@hardimanjames

5 years

I joined @DCVC as the first hire when we had <$100m AUM. Today we announced $725m for our fifth flagship Deep Tech fund. The trajectory has been insane.

Exclusive: Venture Firm Data Collective Raises $725 Million to Invest in ‘Deep Tech’

The firm invests in companies solving highly technical problems.

fortune.com

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James Hardiman

@hardimanjames

10 months

Excited to continue to back entrepreneurs building deep tech companies to transform industries and address the world's challenges And thankful to our LPs for entrusting us to do so

DCVC announces $1 billion in fresh funding; releases inaugural DCVC…

A decade and a half into our work backing deep-tech founders solving the hardest real-world problems computationally, we are pleased to announce having…

www.dcvc.com

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James Hardiman

@hardimanjames

10 months

Absolutely NO ONE tell Cramer about Deep Tech. We got a good thing going over here and I don’t want it getting f*cked it up.

Jim Cramer

@jimcramer

10 months

Enterprise software is where the money is going!!

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James Hardiman

@hardimanjames

10 months

Not if you’re building in deep tech it’s not. @DCVC recently announced $1B+ in new funds to back ambitious entrepreneurs tackling the worlds most important problems. If this describes you, consider getting in touch.

Steph Mui

@stephmui

10 months

Is it really the worst time to fundraise in history??? I wanted to make sure, so I asked my smartest VC & founders-who've-raised-recently friends and this is what they said:

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James Hardiman

@hardimanjames

8 months

@JayaGup10 Deep Tech VC: Hundreds of satellites in space, novel life saving treatments, nitrogen fertilizer with zero emission, rapid wildfire response and prevention B2B Enterprise VC: 15 min office supply deliver

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James Hardiman

@hardimanjames

8 months

Deep tech entrepreneurs are still like the top row … 💪🏻 🚀 ✈️ 🤖 🦠 🏥 💪🏻 Sequencers in basements. Rocket engines on bicycles. Optics tables in garages. Every one of those is a real story.

Ankur Bagchi

@JustAnkurBagchi

8 months

What happened to startup culture?

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James Hardiman

@hardimanjames

6 years

Just finished Prediction Machines by Ajay Agrawal @joshgans & @avicgoldfarb . Wow. I have been investing in AI companies for years @DCVC and still found this a very insightful read. Here are some of my crib notes 1/n

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James Hardiman

@hardimanjames

8 months

Excited to finally be able to talk about what @ron_alfa , Jacob Rinaldi, and the whole @noetik_ai team have been working on Spatial biology + AI = better cancer therapies, faster More here:

DCVC Leads $14 Million Seed Round for Noetik

Noetik is using spatial biology and machine learning to unravel the complex circuitry of cancer, and aims to empower pharmaceutic teams to develop better…

www.dcvc.com

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James Hardiman

@hardimanjames

4 years

Lots of fun chatting the VC perspective on QC at @techreview #FutureCompute 💯 speaker line up & multiple call outs to @dcvc backed @rigetti , @qctrlHQ , @proteinqure (+more @creativedlab QML cos) and even some talk of blind QC ( @horizon_quantum !) Photo credit: @Travis_Sch

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James Hardiman

@hardimanjames

3 years

Huge congrats to @RecursionChris and the @RecursionPharma team. You’re just at the beginning of decoding biology. Excited to see where you go from here!

Nasdaq Exchange

@NasdaqExchange

3 years

3, 2, 1... 🎉 Live from Salt Lake City, UT, @RecursionPharma rings the @Nasdaq Opening Bell in celebration of today's #RecursionIPO !

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James Hardiman

@hardimanjames

1 year

Hearing from multiple companies they are transferring money INTO Silicon Valley Bank. Literally the safest place to bank right now.

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James Hardiman

@hardimanjames

2 years

@maiab Management fee is effectively a loan. VCs have to “pay it back” before they start taking carry. It’s not like double dipping.

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James Hardiman

@hardimanjames

10 months

@terronk And they opened shop over night with out any permits

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James Hardiman

@hardimanjames

4 years

This is BS. I will die on this hill.

Alan Chen (now on bsky.social too)

@profalankchen

4 years

The one-spacers have won. Microsoft Word now showing 2 spaces after a period as an error.

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James Hardiman

@hardimanjames

5 years

Lord - grant me the confidence of the man taking a phone call from the backseat of our Uber pool.

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James Hardiman

@hardimanjames

4 years

Energy storage is one of the pressing issues of our time @ADVANOTech simultaneously improves energy density, reduces total cost, can scale to global demand, & fits into existing battery manufacturing infrastructure Proud @DCVC was an early supporter!

Advano Delivers Scalable Advanced Silicon Solution To Battery Industry Announcing $18.5 Million In...

/PRNewswire/ -- Advano, the company that has created a scalable, affordable solution to improve the battery life of today's rechargeable batteries and is...

www.prnewswire.com

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James Hardiman

@hardimanjames

5 years

To the group with the bubble blowing dance party on top of twin peaks at 7am this morning: Stay SF awesome 🕺🏼

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James Hardiman

@hardimanjames

10 months

@michaelmiraflor Simplest method I’ve heard: Alternate. One non-fiction. One fiction.

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James Hardiman

@hardimanjames

4 years

@lpolovets Power law + buying in at 2.1m post money and then getting everyone else to do the deal at 8-20m post money 3 months later.

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James Hardiman

@hardimanjames

5 years

To have and to hold, from this day forward, for better, for worse, for richer, for poorer, in sickness and in health, til death? @joannezchen : I do. Also, to never watch ahead on a shared Netflix show? @joannezchen : Impossible.

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James Hardiman

@hardimanjames

4 years

2020 has been tough, but the future is bright I know because I am lucky enough to see the 1000s of hardworking people across the @DCVC portfolio _creating_ that future every day Tune in to this thread and you can hear directly from them too

DCVC

@DCVC

4 years

/thread DCVC portfolio companies employ thousands of talented engineers, scientists and PhDs who work on frontier technologies. They have a unique perspective on the progress we’re making and the reasons we should be optimistic for the future. #ReasonsforOptimism

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James Hardiman

@hardimanjames

3 years

Congrats @joannezchen ! Demonstrating you are the better half since 2016.

Joanne Chen just became the first woman GP at Foundation Capital since founder Kathryn Gould |...

Joanne Chen just became the second female general partner in the history of the now 26-year-old, Silicon Valley venture firm, Foundation Capital. Were she

techcrunch.com

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James Hardiman

@hardimanjames

4 years

A twitter story in three acts 😲😀😫 Oh hey there @mattocko ...

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James Hardiman

@hardimanjames

1 year

@amasad Perfect! Exactly the counter balance we needed to put us back on track after this:

Jim Cramer

@jimcramer

1 year

AI, that's the story.. It's changing the world...

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James Hardiman

@hardimanjames

10 months

Get this man a venture fund STAT @BenAffleck

Jon Erlichman

@JonErlichman

10 months

In 2003, Ben Affleck predicted Spotify and Netflix streaming before either existed.

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James Hardiman

@hardimanjames

5 years

Excited that -- after co-leading the Series A with @rootvc -- @DCVC can continue to support @brad_rothenberg & @ntopology in re-inventing engineering tools. Welcome @hrachs and @carlbass to the board!

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James Hardiman

@hardimanjames

5 years

Great post by @zackbogue on how @DCVC is wielding VC to fight climate change, disease, and in general make the world more resilient. Good returns while doing good.

Zachary Bogue

@zackbogue

5 years

Responding to the climate emergency is the defining set of hard technical problems of our time. Read more about @DCVC ’s resiliency thesis on the @WEF Agenda Blog.

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James Hardiman

@hardimanjames

1 year

Perspective / reflection on what led up to the SVB situation from a very senior friend at a top global bank who isn't allowed to tweet. This is more background context than the more recent events of the past week 1/n

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James Hardiman

@hardimanjames

4 years

@noampomsky 😂😐😭 Minor correction tho - as you get older you have to work out harder 😞

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James Hardiman

@hardimanjames

4 years

Going through some papers and came across this Valentine’s Day card for @joannezchen from a few years ago. Nailed it.

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James Hardiman

@hardimanjames

1 year

@richard_murray6 @DCVC Thanks, @richard_murray6 ! I’m glad I had a positive impact. I talk to 100x more companies than I fund and this is an enormous compliment. 🙏🏻

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James Hardiman

@hardimanjames

6 years

Interested in quantum computing? @DCVC portfolio company @rigetti is inviting the best and brightest in the developer community to its first (read: first anywhere) QC Hackathon. Apply here: PhD in QC not required!

This link will take you to a page that’s not on LinkedIn

lnkd.in

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James Hardiman

@hardimanjames

3 years

One my earliest memories at @DCVC is being in a conference room w/ Karsten Temme and @mattocko when Matt offered to lead @pivotbio 's 1st round Amazing to see Pivot from moon shot to moon landing Congrats to the entire Pivot team and h/t to Matt

Pivot Bio Nears $2 Billion Valuation As It Raises Whopping $430 Million To Replace Synthetic...

Pivot Bio broke the code on using microbes to get crops to self-fertilize, allowing farmers to replace their synthetic chemical fertilizers. It's now worth nearly $2 billion.

www.forbes.com

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James Hardiman

@hardimanjames

1 year

Gave up coffee at the beginning of the year in order to try and sleep better. My nights are better, but my mornings are joyless.

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James Hardiman

@hardimanjames

4 years

@terronk There’s a faster way. It involves two MIT grads that invented a unique algorithm ...

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James Hardiman

@hardimanjames

10 months

No matter where I’m going in SF I always think: “Yeah - that’ll take about 15 minutes” As a VC can never lose that optimism

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James Hardiman

@hardimanjames

10 months

Received a company update today and it is 🚀🚀🚀 Macro be damned, just keep building

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James Hardiman

@hardimanjames

8 years

. @DCVC & @trueventures co @healthgorilla enabling seamless HIPAA-compliant comm. across @ScrippsHealth ecosystem

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James Hardiman

@hardimanjames

4 years

When your dinner conversation starts off with, “So one of the key tenants of Sith philosophy is The Rule of Two ...” you know you found the right woman. @joannezchen

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James Hardiman

@hardimanjames

6 years

“We invest in companies that have a compelling solution to a real problem - regardless of the underlying tech, AI or not” - @joannezchen @FoundationCap #MITAI

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James Hardiman

@hardimanjames

5 years

If you’re looking to learn more about quantum machine learning here’s a great MOOC put out by @UofT here: cc: @creativedlab

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James Hardiman

@hardimanjames

5 years

Under no circumstances should my computer be slower than my brain and/or fingers - looking at you Outlook and Excel

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James Hardiman

@hardimanjames

5 years

$70B+ a year are spent on clinical trials. If you care at all about making this critical part of medicine better and faster you need to know @charleskfisher what he and his team are building at @UnlearnAI

Charles Fisher

@charleskfisher

5 years

I don't like the concept of statistical significance because it is more important to know "is the effect big" than "what would we have observed if there was no effect". Here's a simple a way to interpret clinical trials without statistical significance

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James Hardiman

@hardimanjames

1 year

“Startups are a marathon, not a sprint. But also remember that people who are serious about marathons run them at 5min per mile pace” Credit to serious startup marathoners @Eduardo3rd and the @lumafield team

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James Hardiman

@hardimanjames

5 years

No one slept much the first few years ( @mattocko still doesn't😉) & I'm proud of what we've built cc: @zackbogue @SABarclay @armenvidian @kaychen22 @alitamaseb @cboshuizen @johncumbers @ascohen @mattmichelsen @bradfordcross @medriscoll @2kstead @annafokina John H. Jeremy J.

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James Hardiman

@hardimanjames

1 year

Thanks @TheEconomist for hosting me at “Commercialising Quantum” today! Excited about the quantum computing opportunities of tomorrow and the quantum sensing opportunities of today!

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James Hardiman

@hardimanjames

5 years

Srsly LinkedIn? Your name search is so bad that it's better to search "first last linkedin" through Google when trying to find people.

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James Hardiman

@hardimanjames

5 years

Made storage cabinets for my garage today. In an increasingly digital world it can be therapeutic to work with your hands.

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James Hardiman

@hardimanjames

11 months

@octal I would also expand this to include other top government officials. We’d get better talent if the comp was better.

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James Hardiman

@hardimanjames

1 year

One of the best things about being in the bay area is that you're surrounded by unbridled ambition

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James Hardiman

@hardimanjames

10 months

@JonBruner Now I’m wondering what they’ll look like in MY BELLY

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James Hardiman

@hardimanjames

1 year

Shoutout to @nathanbenaich of @airstreet for hosting a packed house on LLM best practices

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James Hardiman

@hardimanjames

10 months

In person board meetings are 100x better

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James Hardiman

@hardimanjames

7 years

. @zackbogue kicking off the @dcvc + Silicon Valley Deep Learning Group; talking about Creative Applications of DL

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James Hardiman

@hardimanjames

1 year

@proetrie Celsius is great for water Fahrenheit is great for people

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James Hardiman

@hardimanjames

1 year

If you put your personal item in the overhead bin instead of under your seat … and then make a big deal about it when someone kindly asks you to move it so they can put their carry-on luggage there … … then you’re an asshole

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James Hardiman

@hardimanjames

6 years

Thanks for the great conversation @TheFullRatchet ! Glad to be able to chat a little about some of the things my partners @mattocko @zackbogue @SABarclay @armenvidian and I are up to at @DCVC

Nick Moran

@TheFullRatchet

6 years

Investor @hardimanjames of @DCVC joins me to discuss why the defensible, monopolistic, largest tech outcomes will come from Deep Tech:

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James Hardiman

@hardimanjames

4 years

I’ve gotten more work done on weeks I was on vacation than this one

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James Hardiman

@hardimanjames

1 year

Excited to finally be able to talk about @DCVC 's investment in ShennonBio - which is accelerating immunotherapy target discovery. Congrats to Li Sun and the entire ShennonBio team on coming out of stealth.

DCVC leads $13 million seed funding for ShennonBio—revolutionizing…

San Francisco–based biotech startup ShennonBio brings radical progress to immunotherapy, which harnesses the power of the body’s immune system to fight…

www.dcvc.com

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James Hardiman

@hardimanjames

6 months

@zebulgar Have to admit that it’d be hilarious if someone nominated you and you were selected anyway

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James Hardiman

@hardimanjames

5 years

I am also thankful to all the entrepreneurs we've been fortunate enough to back and work alongside. They are the reason we get to do what we do. There are too many to list, but if you're curious then many of the companies can be seen here:

DCVC | Home

We are deep tech venture capital.

www.dcvc.com

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James Hardiman

@hardimanjames

6 years

“Under appreciated enabling tech in space revolution is access to on demand supercomputer and advances in simulation and engineering tools” - @mattocko @rescale @ntopologyinc #TCDisrupt

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James Hardiman

@hardimanjames

4 years

“‘Deep Tech’ offers an investment opportunity at least 5-10 times larger than most of venture funding's current focus.” Great insights from my partner @zackbogue in case you missed them

This is how venture capital can fuel a brighter future

By investing in AI, cloud computing, robotics and more, venture capital could reshape major global industries to help offset and possibly reverse the excesses of capitalism.

www.weforum.org

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James Hardiman

@hardimanjames

7 years

Impressive group of companies @indbio demo day. Getting better every time. Check out for those that missed it.

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James Hardiman

@hardimanjames

6 years

Inbox zero for the first time in my life and, yes ... it was as amazing as I hoped.

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James Hardiman

@hardimanjames

10 months

Hell hath no fury like a founder scorned

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James Hardiman

@hardimanjames

1 year

Three years ago I wrote an internal investment memo titled 'Rebuilding the Tower of Babel' about NLP and it’s missing 'image net' moment Was fun to revisit as ChatGPT has clearly been that moment ... 1/n

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James Hardiman

@hardimanjames

2 years

Huge congrats to @MJBiercuk and the entire @qctrlHQ team on their Series B! Glad we at @DCVC were early supporters!

Sydney-based quantum sensing startup Q-CTRL raises $25M Series B led by Airbus Ventures | TechCrunch

Q-CTRL, a Sydney-based startup that provides quantum control engineering solutions, announced today it has raised a $25 million Series B led by Airbus

techcrunch.com

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James Hardiman

@hardimanjames

6 years

Thanks for having me on Equity Podcast @alex & @Katie_Roof ! Enjoyed the banter and a shameless plug for my @Lenovo ThinkPad work horse @TechCrunch

Equity podcast: Everyone beats earnings, racing to $1 trillion and Square goes shopping

Hello and welcome back to Equity, TechCrunch’s venture capital-focused podcast where we unpack the numbers behind the headlines. Today Katie Roof and I were joined by James Hardiman, a partner at...

techcrunch.com

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James Hardiman

@hardimanjames

3 years

Climate change is going to be hard to fix, but companies like @pivotbio help put a dent in it. Read more from my partner @ascohen

Alan Cohen

@ascohen

3 years

. @TIME recognizes @DCVC co @pivotbio as one of 2020's Best Inventions. Really proud of @karsten and the Pivoteers, reimagining agriculture, improving farmer economics, and rolling back the climate clock

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James Hardiman

@hardimanjames

5 years

Finally, if you are an ambitious founder building an applied AI or Deep Tech company that is transforming an industry ... get in touch!

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James Hardiman

@hardimanjames

1 year

You know you’ve made it when other companies start requiring proficiency in your software in order to just apply for a job there 😜 cc: @nTopology @brad_rothenberg

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James Hardiman

@hardimanjames

4 years

This is TERRIBLE position Here’s some better advice: If you feel like you are not informed enough then GO INFORM YOURSELF by doing some reading and THEN go vote.

Robin Hanson

@robinhanson

4 years

Twitter wants me to encourage you to vote. But I'm not going to do that. I instead encourage you to *honestly* ask yourself if you are better informed than other likely voters about which candidates are better for us all. Just cause you have a side/team, doesn't mean better info.

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James Hardiman

@hardimanjames

7 years

. @AppCardiogram literally saving lives through detecting Afib, sleep apnea, and more #googleMLcompetition @DCVC

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James Hardiman

@hardimanjames

3 years

Huge news. @SubtleMedical -- already driving value for MDs and patients across imaging modalities -- continues to work on expanding their product lines.

Subtle Medical, Inc.

@SubtleMedical

3 years

We are thrilled to announce patent issuance of our #AI -powered technology w/ enables a 90% dose reduction in contrast-enhanced medical imaging! Another milestone in our mission to accelerate access to faster, safer, & smarter medical imaging! #SubtleGAD 👉

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James Hardiman

@hardimanjames

10 months

Sell it all. Today.

Jim Cramer

@jimcramer

10 months

Enterprise software is where the money is going!!

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James Hardiman

@hardimanjames

4 years

So my scale is telling me its batteries are low and refusing to weigh me Considering the time of year I cannot say I am upset about this 🤷🏼‍♂️😋

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James Hardiman

@hardimanjames

6 months

I remember when @MJBiercuk pitched me in 2018 on the idea that @qctrlHQ software would be a key enabling technology on every quantum computer Amazing to see this vision start becoming a reality Disclaimer: A happy investor in this one ;)

Michael J. Biercuk

@MJBiercuk

6 months

This is an amazing milestone for the #QuantumComputing industry. @qctrlHQ is proud to be the first #ISV to integrate with a major #quantum platform - our friends & partners at @IBM Now access #performancemanagement at no additional cost on IBM Quantum!

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James Hardiman

@hardimanjames

1 year

@arjunsethi Was doing frontier, space, & manufacturing before it was cool … and still doing them now! Same with applied AI. First check into a generative AI company was *checks notes* 2017

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James Hardiman

@hardimanjames

8 months

Don’t sleep on quantum. The future comes at you fast.

Michael J. Biercuk

@MJBiercuk

8 months

The team @qctrlHQ is very happy to announce our UK teams win on a new Quantum Catalyst fund bringing our exceptional optimization capabilities for #quantumcomputing to #energy !

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James Hardiman

@hardimanjames

1 year

If you’ve been in SV long enough you’re gonna have stories of selling too early/not soon enough, passing on unicorns, and some fantastical blow ups.

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James Hardiman

@hardimanjames

8 months

Bro! About time! @zebulgar

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James Hardiman

@hardimanjames

1 year

Amazing to have JPM back in person this year. Got to see a lot of old friends and meet new people creating the future.

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James Hardiman

@hardimanjames

1 year

There are two kinds of people in this world. Those who put the cap back on the toothpaste when they’re done and those who wake up and choose chaos every morning.

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James Hardiman

@hardimanjames

4 years

‘The reasonable man adapts himself to the world; the unreasonable man persists in trying to adapt the world to himself. Therefore all progress depends on the unreasonable man.’ - George Bernard Shaw 🥂 to all the unreasonable men and women out there

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James Hardiman

@hardimanjames

8 months

@peteskomoroch @AaronPeskin @DeanPreston I literally can’t understand the behavior of our supervisors

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James Hardiman

@hardimanjames

10 months

Amazing how many exceptions there are in venture. A business of extremes. 99% of the time something could be a bad idea and then that 1% of the time … it’s the BEST idea

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James Hardiman

@hardimanjames

8 months

In case you missed it last week, @noetik_ai launched out of stealth with $14m in funding - led by @DCVC - to use spatial biology to develop immune-oncology drugs Great article today from @GENbio

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James Hardiman

@hardimanjames

6 months

Entrepreneurs out here doing God’s work every day Congrats @celinehalioua and the whole @loyalfordogs team Disclaimer: Not an investor. Just a fan.

Celine Halioua

@celinehalioua

6 months

1 - Loyal has earned what we believe is the FDA’s first-ever formal acceptance that a drug can be developed + approved for lifespan extension 2 - We have 'technical section complete' AKA the 'does it work' data for LOY-001 - our large dog lifespan extension drug - is done

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James Hardiman

@hardimanjames

4 years

Another $12m to help make clinical trials faster and more statistically robust Congrats to @charleskfisher , @MathAdapted , Jonathan Walsh, and the whole @UnlearnAI team!

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James Hardiman

@hardimanjames

7 months

If two people are on an email - the chance that anyone responds goes down 95% There a term for this?

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James Hardiman

@hardimanjames