Eiko Fried @EikoFried Twitter profile | Pikagi

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Eiko Fried

@EikoFried

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Associate Prof @UniLeiden . Mental health & data science. Building early warning system for depression ().

Mostly Europe

https://t.co/Lp6I4Ayb10

Joined April 2013

Don't wanna be here? Send us removal request.

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@EikoFried

Eiko Fried

2 years

🔥 Folks—there's a new paper in town, and I'd love to tell you about it. In the paper I wrote with @JkayFlake & Don Robinaugh, we take a bird's eye view on depression measurement. History, present, future. In particular, we discuss shaky theoretical & methodological foundations🧵

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@EikoFried

Eiko Fried

2 years

In case you were wondering what paths 800 unsteered bicycles take when you push them:

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@EikoFried

Eiko Fried

4 years

My standard response when I'm invited to editorial boards without recompense. I don't think working for free as a highly trained professional is or should be normal, & I think we need to continue to call this out clearly. The more of us do, the more likely things will change. 1/2

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@EikoFried

Eiko Fried

3 years

My students invented Eiko bootstrapping: you ask the PI the same question a few times, 4-8 weeks apart, and he'll have forgotten he was asked the question before. If he gives the same answer multiple times, we'll call it a robust and reliable outcome.

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@EikoFried

Eiko Fried

5 years

In proofs, copy editor wrote, for a ref with 217 authors: "Don't abbreviate authors with et al.—journal style requires to spell out all names." And because I'm an adult I did the grownup thing: Spelled out 217 names, & also added a ref to the Higg's Boson paper. (｡◕‿◕｡)

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@EikoFried

Eiko Fried

4 months

A very elegant response to so many research papers out there ..

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@EikoFried

Eiko Fried

6 years

One of my all-time favourite papers. Only 18 citations, so I thought I should share. An MD cracked his knuckles for 50 years — but only for one hand. He concludes by calling into question other parental beliefs …

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@EikoFried

Eiko Fried

2 years

🚨New paper alert🚨 "Studying Mental Health Problems as systems, not syndromes" is now published #OpenAccess in Current Directions. I'll summarize the paper briefly here. ⬇️

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@EikoFried

Eiko Fried

6 years

1/6 When you see someone use the Myer-Briggs Type Indicator in a professional context, call them out. It does not meet basic criteria of psychometric scales, was "developed" in the 40s by people without any training, & is based on outdated psychoanalytic ideas. Long version 👇

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@EikoFried

Eiko Fried

6 years

Discovered this beautiful @rstudio #rstats hack a few days ago, wish I had known earlier.

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@EikoFried

Eiko Fried

5 years

When 2 co-authors sent back revisions of the same manuscript simultaneously, and you use "a tool to easily & automatically merge" the 2 versions.

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@EikoFried

Eiko Fried

3 years

New semester starting? Worried about your teaching materials, prep time, or crowded covid classrooms? Freud got you covered.

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@EikoFried

Eiko Fried

2 years

I dedicated my PhD to Aaron’s memory. If you have not heard about his work or life please take a moment to take a look below, and consider the role of scientific publishers play in society.

@RorschachProdu1

Youssef Ibrahim Yazbek 🇱🇧 ☭

@RorschachProdu1

2 years

Aaron Swartz would have been 36 today. Aaron committed suicide after being sentenced to 35 years in prison by US authorities for transferring and sharing scientific articles from JSTOR.

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@EikoFried

Eiko Fried

4 years

As announced by @ERC_Research , I won a 5-year ERC Starting Grant on developing a personalized prediction model for depression onset. I'm overwhelmed, proud, humbled, & a little nervous. See below for details. Also: I'll be hiring early 2021 :)

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ERC Starting Grant on predicting depression onset » Eiko Fried

I’m extremely happy, proud, humbled, and somewhat nervous announce that my application for an European Research Council (ERC) Starting Grant was successful (on my first try!), following the announc...

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@EikoFried

Eiko Fried

2 years

“Eh, sorry sir, can you repeat how to spell that name just one more time?” 5 minutes later:

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@EikoFried

Eiko Fried

2 years

Psychologist looking for the latent variable.

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@EikoFried

Eiko Fried

2 years

You may remember the recent NatureMedicine paper where authors claim to show—as the first author says below—that psilocybin "liberates the entrenched depressed brain". This led to considerable news coverage. 3 pretty remarkable things have happened since this was published 🧵

@neuroDaws

Richard E. Daws

2 years

Just out in @NatureMedicine . Psilocybin therapy liberates the entrenched depressed brain by increasing the global integration of functional networks. It has been brilliant to collaborate w/ @RCarhartHarris @ProfDavidNutt et al.

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@EikoFried

Eiko Fried

2 years

Featured in a German magazine and am so glad the photographer went with the tried and true classic "sad psychologist in the jungle".

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@EikoFried

Eiko Fried

5 years

I have SO MANY QUESTIONS …

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@EikoFried

Eiko Fried

1 year

🔥🔥🔥 Published last week in @NatureHumBehav : Quality research needs good working conditions.

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@EikoFried

Eiko Fried

2 years

A few months back our head of the department asked both me & a colleague to stop in the middle of the hallway for "a case study of the influence of Freud on contemporary psychology" ;)

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@EikoFried

Eiko Fried

3 years

Dutch universities are making a move to abandon the impact factor in recognition and reward considerations. A group of 170 Dutch academics posted a critical response to this initiative. I summarize why these responses fail to convince me. 🧵

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@EikoFried

Eiko Fried

4 years

This is crazy! An editor asked 41 teams to provide data because their manuscripts looked too clean. HALF of the teams withdrew their papers. 1 out of 41 teams provided full data.

@tsuyomiyakawa

Tsuyoshi Miyakawa

4 years

My editorial paper entitled, "No raw data, no science: another possible source of the reproducibility crisis". When I feel the results are too beautiful, I requested raw data before sending it out for review. 40 out of 41 did not send me the right data.

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@EikoFried

Eiko Fried

7 years

1/ Why depression is not a useful or reasonable phenotype for research in clinical psychology, psychiatry, or medicine: a summary of evidence in 18 tweets. Sx = symptoms, MDD = major depressive disorder.

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@EikoFried

Eiko Fried

3 months

Another Elsevier article clearly written by hooomans: "I'm very sorry, I don't have access to real-time informatino as I am an AI language model" 🤖🤖🤖🤖🤖🤖🤖🤖🤖🤖🤖🤖🤖🤖🤖 ()

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@EikoFried

Eiko Fried

2 years

New paper claims to provide “clear evidence” for the serotonin hypothesis of #depression . N = 37, p = 0.04, and in the results you can see that removing a single observation turns the result non significant.

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@EikoFried

Eiko Fried

11 months

I did ALL THE THINGS to get my 100€ reimbursement for a keynote in Germany, including printing some documents 3 times (one-sided!) but other documents only once (double-sided!), and shipped the whole package. Sadly, I used electronic signatures which are NOT accepted in 2023.

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@EikoFried

Eiko Fried

3 years

Starting 11/2020, *ALL* papers by researchers at Leiden University will be made #OpenAccess 6months after publication, no matter where they are published. This includes articles in journals who do not "allow" postprints after 6 months (common in e.g psychiatry, medicine).

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@EikoFried

Eiko Fried

3 years

Best reviewer comment 2020: "I was able to replicate all plots displayed in Figure 2. They are very informative and beautiful." 🖤🖤🖤🖤🖤

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@EikoFried

Eiko Fried

2 years

@katiedimartin Nobody reads until the end of any email so since 2016 I just end my emails in the middle of the last sentence. Nobody’s noticed.

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@EikoFried

Eiko Fried

4 years

Like many of you, I received a DMCA removal request by the @APA a few days ago, asking me to remove the PDF of a paper from my personal website. I wrote them back, & they have rescinded their request. I'll post screenshots of the emails below and hope it helps others.

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@EikoFried

Eiko Fried

6 years

Death stats, Germany 🇩🇪 2017. 👨‍👩‍👧‍👦 = 83 million Home-related deaths: 9k Death by 🍺: 7.4k Death by 🚗🚃: 3.2k Death by 🔪🔫: 405 Death by islamic terror: 1 Death by ✈️: 0 % of Germans afraid to die in islamic terror attack: 70 [Source: Statistisches Bundesamt]

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@EikoFried

Eiko Fried

3 years

Depression trial, n=14 Ayahuasca, n=15 placebo. 8/14 vomited, & 4/14 hospitalized for an entire week. "Overall, this study brings new evidence supporting the safety and therapeutic value of psychedelics." ¯\_(ツ)_/¯

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@EikoFried

Eiko Fried

3 years

Today, Eikobot v3.8 received his first permanent job 🎉

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@EikoFried

Eiko Fried

6 years

Thanks again to everybody who supported be over the last year. There are many more names that I could tag in one tweet: you know who you are.

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@EikoFried

Eiko Fried

1 year

🔥🔥🔥 "Purely behavioral research is essential for understanding the brain [..], contrary to the opinion of prominent funding bodies and some scientific journals, who erroneously place neural data on a pedestal and consider behavior to be subsidiary"

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@EikoFried

Eiko Fried

11 months

A lot of reforms in psych science in the last decade have focused on improving statistical practices (and that's great). But, as the many of us who have re-analyzed a lot of data can tell you: statistics really cannot help you much when your measures are problematic or invalid.

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@EikoFried

Eiko Fried

1 year

Editorial in Current Psychiatry suggests that "the deactivation of the default mode network by excessive use of social media may explain the mental health decline in youth." I show in this blog post why this claim makes no sense.

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Is the 'default mode network' responsible for the mental health crisis in youth? » Eiko Fried

New editorial proposes that the default mode brain network is responsible for mental health crisis in youth. I show that this idea is false.

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@EikoFried

Eiko Fried

3 years

Some rejections hurt more than others, but having a paper rejected half a year after publication is something new ...

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@EikoFried

Eiko Fried

3 years

Just published: "The Open Handbook of Experience Sampling Methodology". You can download it for free on this website! Huge thanks to the team at Leuven University for this massive contribution.

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@EikoFried

Eiko Fried

3 years

Added a disclaimer to my website today, after receiving yet another email by a publisher asking me to remove my own work from my own website. Thanks 🇳🇱 for being a global leader in the #OpenScience reform! (more info on Taverne here:)

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@EikoFried

Eiko Fried

5 years

@PughRhiannon Just in case you think this is a constructive way forward and not just a waste of time — I'd be very happy to sign an open letter to the funder to put on some public pressure, and share this open letter among my colleagues. There were cases where this has helped in the past.

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@EikoFried

Eiko Fried

4 years

In case you are still using SPSS: check out JASP. JASP -is free & easy to use -has many SPSS core features -has nice data vis, Bayesian analyses, network analyses, etc. -outputs tables in APA format -is written by psychologists for psychologists.

JASP - A Fresh Way to Do Statistics

JASP is an open-source statistics program that is free, friendly, and flexible. Armed with an easy-to-use GUI, JASP allows both classical and Bayesian analyses.

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@EikoFried

Eiko Fried

1 year

New #depression #psiloybin has 2 severe issues. (1) They don't adhere to their protocol registered on & report primary outcomes at week 2, when week 4 was registered. I'm so frustrated that scientists (but also reviewers & editors) don't do their job.

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@EikoFried

Eiko Fried

7 months

1/12 New paper on psychedelics as treatments for mental health problems! We discuss 10 challenges which limit conclusions that can be drawn about safety/efficacy of psychedelic therapy. We share checklist for journalists, policymakers & others to assess study quality. 🧵

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@EikoFried

Eiko Fried

3 years

@BettySLai @OpenAcademics Not only do I send myself emails. I am genuinely surprised when I receive an email a second later "oooh I wonder who sent this"...

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@EikoFried

Eiko Fried

2 years

Lots of discussions around the new #serotonin #depression paper published yesterday in Biological Psychiatry. Given that big news outlets like the Guardian already covered the piece, I wrote up the core issues I see with the main conclusions in the paper.

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"Clear evidence" for serotonin hypothesis of depression? » Eiko Fried

A recent paper argues they find "clear evidence" to support the serotonin theory of depession. I show that this is not the case.

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@EikoFried

Eiko Fried

3 months

Fantastic piece by Marten Scheffer on the forgotten half of thinking: ".. taking walks, reading things unrelated to your research, and hanging out with strangers in a campus pub should be considered part of the serious process of thinking .."

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The forgotten half of scientific thinking | Proceedings of the National Academy of Sciences

The forgotten half of scientific thinking

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@EikoFried

Eiko Fried

3 years

"There is no scale on X. X is super important. Here we develop a scale, & our validation study show it has decent properties. However, we obviously don't share our scale. Nor tell you where to get it. Nor rules about its use." How👏does👏this👏still👏get👏published👏in👏2021?

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@EikoFried

Eiko Fried

4 years

Our (led by the brilliant @JkayFlake ) Schmeasurement paper on questionable measurement practices is now published, in the December issue of Advances in Methods and Practices in Psychological Science.

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Measurement Schmeasurement: Questionable Measurement Practices and How to Avoid Them - Jessica Kay...

In this article, we define questionable measurement practices (QMPs) as decisions researchers make that raise doubts about the validity of the measures, and ult...

journals.sagepub.com

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@EikoFried

Eiko Fried

4 months

Neuroimaging research in psychology has led to so many false positive, non replicable findings due to questionable research practices & publication bias that Science Advances now publishes null findings to clean up the literature (this is from 2022).

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Absence of structural brain changes from mindfulness-based stress reduction: Two combined randomi...

This study found no evidence that 2 months of training in mindfulness meditation among novices produced neurostructural changes.

www.science.org

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@EikoFried

Eiko Fried

5 months

1/22 Our new paper led by @ashleylwatts (w @ashlgreene & @wesbonifay ) is now published; I view it as the first critical evaluation of the statistical and theoretical p-factor & resulting literature. Here a brief overview of the core arguments in the paper.

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@EikoFried

Eiko Fried

5 months

Did you know of this meta-analytic website by @pimcuijpers et al. featuring hundreds of RCTs? In the video I'll show researchers (part I) and clients (part II) how to run a systematic meta-analysis looking into the effect of CBT on depression in older adults within 1 minute.

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@EikoFried

Eiko Fried

7 months

Very cool website, R package, and tutorial paper on preprocessing data from ESM / EMA studies. Website: Preprint:

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@EikoFried

Eiko Fried

5 years

"Please note that the secret reviewer police has identified secret problems with the paper that you as author have no access to, and, therefore, cannot address." The system is so broken it's ridiculous.

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@EikoFried

Eiko Fried

2 years

New blog in which @robinnkok & I describe what data Elsevier collects, & what to do about it. Teaser: private phone numbers, IP addresses, what papers you read & when, what actions you perform in Mendeley & when, which emails you read, and much more.

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Welcome to Hotel Elsevier: you can check-out any time you like … not » Eiko Fried

A journey by Robin Kok and Eiko Fried trying to understand what private data Elsevier collects; what private data Elsevier sells; and what to do about it.

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@EikoFried

Eiko Fried

5 years

When you finish a PhD in clinical psych they take you in a room and tell you that diagnoses aren't real; have limited reliability, validity, & utility; that treatments only work for 1/2 your patients; that many treatments work equally well; that many get better without treatment.

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@EikoFried

Eiko Fried

4 years

I work in academia and use sci-hub:

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what is sci-hub

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@EikoFried

Eiko Fried

4 years

That's nonsense -- many of us have 1 or 2 yr contracts after which we have to switch unis / countries and our old email addresses expire. I use my gmail address because I won't put an institutional email on a paper that is invalid after 2 years.

@mortenoxe

Morty 🇺🇦

4 years

Let me give you an advice, if you are a scientist or publisher: Never touch a manuscript if the authors use non-institutional e-mail addresses. Trust me, it will save you a lot of time and frustrations. #Papermill @Pubpeer

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@EikoFried

Eiko Fried

2 years

"Studying mental health problems as systems, not syndromes" online now. It's a short piece that I substantially rewrote in the last 6 months, and I think it has much improved. 1/19

Studying mental health problems as systems, not syndromes

Despite decades of clinical, research and sociopolitical efforts, progress in understanding and treating mental health problems remains disappointing. I discuss two barriers that have contributed to...

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@EikoFried

Eiko Fried

1 month

Stunning video: neuroscience professor Huberman claims an event with 20% probability has a 100% probability to occur if repeated 5 times. That’s not how probability works (1-(.8^5)), and a coin’s probability to hit “tails” after second flip is not 50% + 50% = 100% (1-(.5^2)).

@Andercot

Andrew Côté

1 month

Andrew Huberman is scientifically illiterate

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@EikoFried

Eiko Fried

3 years

I really dislike "brain health" when talking about emotional/mental health problems. It attributes problems often due to stressors & external events, stigma, discrimination, & adverse healthcare/political systems to an individual/their brain.

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@EikoFried

Eiko Fried

5 years

Rant to a copy editor that it is not reasonable to demand proofs within 48 hours.

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@EikoFried

Eiko Fried

3 years

One of the many examples why I find measurement in psychology so fascinating: people use response processes we don't fully understand to answer items.

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@EikoFried

Eiko Fried

3 years

Civil disobedience in scientific authorship: Resistance and insubordination in science (h/t @Chops310 )

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@EikoFried

Eiko Fried

6 years

When different models have the same fit in the same data, we talk about 'model equivalence'. The gif below (via Denny Borsboom) highlights this phenomenon very well. For equivalence between network and latent variable models, see Denny's guest blog here:

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@EikoFried

Eiko Fried

2 years

@myriam_sander Making mistakes in science is normal and ok—so sorry to see it leads to retractions here, but that should also be normal. Thanks for doing the right thing and sharing transparently. You’re helping many others by normalizing mistakes.

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@EikoFried

Eiko Fried

3 years

Brief comment on the new "breakthrough study" on #depression blood tests. 🧵 TLDR: there is no blood test for depression.

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A Blood Test For Depression and Bipolar Disorder - Neuroscience News

A new blood test can distinguish the severity of a person's depression and their risk for developing severe depression at a later point. The test can also determine if a person is at risk for...

neurosciencenews.com

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@EikoFried

Eiko Fried

6 months

In this paper published yesterday on using psychedelics to improve wellbeing in cancer patients, the first author Agrawal, CEO of a psychedelics company to improve wellbeing in cancer patients, has "no conflicts of interest" to declare. ¯\_(ツ)_/¯

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@EikoFried

Eiko Fried

1 year

Brief reminder that folks in Leuven have written an open, free handbook on #EcologicalMomentaryAssessment you can download here:

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@EikoFried

Eiko Fried

2 years

After yet another overhyped study in a top journal on psychedelics as treatment for depression, I wrote a blog about the biggest challenges of the literature. Hopefully useful for clinicians & researchers, but also journalists & folks w lived experiences.

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Treating depression with psychedelics: red flags and FAQ » Eiko Fried

Studies claim psychedelics provide effective treatments against depression. Here I show you why this is not the case.

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@EikoFried

Eiko Fried

6 years

And I tell my students to avoid applying for labs where PIs say:

@NAChristakis

Nicholas A. Christakis

6 years

I tell my graduate students and post-docs that if they’re working 60 hours per week, they’re working less than the full professors, and less than their peers.

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@EikoFried

Eiko Fried

3 years

New blog post on theory, summarizing ~4 yrs of work. I introduce theories, models, phenomena, data, & their relations; explain what Meehl, the hypothetico-deductive framework & the #openscience reform have in common; and why formal models can help us.

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On Theory » Eiko Fried

What is a good theory, and what is a bad one? In this blog, I'll introduce theories, models, phenomena, data, and how they relate to each other.

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@EikoFried

Eiko Fried

7 months

Yet another mental health marker that is transdiagnostic because — repeat after me — DSM disorders were created as pragmatic categories with the goal to be clinically useful. There is no reason to expect markers to behave differently.

@HansenLasse94

Lasse Hansen

7 months

Can we predict a psychiatric condition (depression, schizophrenia) from voice? Many studies say yes! Our work in Nature Mental Health shows that such markers do not discriminate between conditions, and we should search for markers of specific symptoms common across conditions.🧵

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@EikoFried

Eiko Fried

5 years

Good news: * After 1 yr @UniLeiden I was promoted from UD2 to UD1 (junior to senior Assist. Prof.) * We (PI Anita Jansen @MaastrichtU ) got the Gravitation grant: 20€ million for 10 yrs, for transdiagnostic within-person network analyses of mental illness & interventions. 1/4

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Eiko Fried

1 year

Before approving psychedelics as medicines, Australia commissioned an independent scientific report into risks & benefits. They then approved *against* the report's advice. Now, the chief scientist speaks out in a remarkable editorial; brief summary 🧵.

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The down-scheduling of MDMA and psilocybin(e): Too fast and too soon - Steve Kisely, 2023

journals.sagepub.com

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@EikoFried

Eiko Fried

3 years

Our primer on psychological networks is published! So happy that there are still journals out there willing to publish manuscripts with tons of figures. Short 🧵

@MethodsPrimers

Nature Reviews Methods Primers

@MethodsPrimers

3 years

Network analysis lets you study complex patterns and relationships and their connections to each other. Our newest Primer outlines how to use network analysis in psychological research. Check it out here:

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@EikoFried

Eiko Fried

1 year

Disappointing @LastWeekTonight on psychedelic assisted therapies. Not *one* sentence on bad science, small & unrepresentative samples, dangers of open label studies, lack of followups. 7 positive n=1 stories, 0 coverage of the many negative ones.

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You Won’t Feel High After Watching This Video

Psychedelic therapy was supposed to treat her PTSD. Instead, it traumatized her even more.

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@EikoFried

Eiko Fried

4 years

NO IT ISN'T (╯°□°）╯︵ ┻━┻

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@EikoFried

Eiko Fried

5 months

1/8 New tutorial preprint led by @b_siepe in which we present different descriptive statistics & data visualization techniques with the goal to better understand EMA item functioning. Preprint: Brief overview thread 🧵:

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@EikoFried

Eiko Fried

4 years

I learned about simulation studies late, in my 1st postdoc; never heard about them before in grad school. Then I joined a methods group in 2014, and "just do a sim study" was the standard answer to about any question I had. It was a crucial thing to learn, because now ..

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@EikoFried

Eiko Fried

2 years

How’s your day going 🥲

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@EikoFried

Eiko Fried

6 years

Paper of colleague was rejected recently. Editor: "The study reports a null finding, which, as you know, is uninterpretable. My decision is based on whether the work provides truly new and novel findings." Let me repeat what I wrote on Facebook a few days back:

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@EikoFried

Eiko Fried

7 years

sci-hub.cc seems down, sci-hub.bz is working. I have set my search engine options in chrome so that I only have to type "sh", tab, & paste DOI to directly obtain PDFs (obviously I only do that for journals my university has access to).

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@EikoFried

Eiko Fried

1 year

Took Miri and the gang over half a decade to conduct over a million comparisons, and it was worth it. Humbled to be part of this paper mapping out the DSM.

@MiriForbes

Miri Forbes

1 year

Ever wondered how many symptoms make up all of adult psychopathology described in the DSM-5? It’s 628! How many do you think repeat across multiple diagnoses? If you answered 231 symptoms repeating a total of 1022 times (median 3 times per symptom, range 2-22), good job! 🧵

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@EikoFried

Eiko Fried

2 years

6/6 I hope the authors of the rebuttal will re-consider these sections & stick to scientific arguments that scientists who read this debate are interested in. To conclude, you can find a summary of general issues I see with this literature here.

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Treating depression with psychedelics: red flags and FAQ » Eiko Fried

Studies claim psychedelics provide effective treatments against depression. Here I show you why this is not the case.

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@EikoFried

Eiko Fried

6 years

I dun goofed: Someone found an error in a paper I had published 2017. Here I describe the error & correct it; show how sharing code online allowed someone else to find it; & suggest that we talk more about failure in academia.

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Failure of the week » Eiko Fried

In our Clinical Psychology group in Leiden, we have the tradition to share new papers, accepted grant proposal, and other achievements in emails called “Paper of the Week”, “Grant of the Week”, and...

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@EikoFried

Eiko Fried

5 years

Eiko needs to write grant: cleans up, cooks crazy dinner, goes to the gym 2 times / day. Hello social media. Eiko needs to make figure for grant: 36 hours focus work without sleep & food, still excited. I need to switch job. Someone want to hire a "figure maker"?

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@EikoFried

Eiko Fried

1 year

I asked #ChatGPT to list scientific paper estimating prevalence rate of depression in young adults. The estimate rates made sense, and paper titles and authors all seemed (vaguely) familiar. But none of the papers actually exist.

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Using GPT-3 to search for scientific "references" » Eiko Fried

I have been playing around with GPT-3 and its chatbot in previous weeks, and found it fascinating. GPT-3——the Generative Pre-trained Transformer 3——is a deep learning language model developed by OPEN...

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@EikoFried

Eiko Fried

4 years

Apparently I made it onto this "highly cited researchers" list (top 1% per field). Citations aren't necessarily linked to research quality of course, but I'm pre-tenure, and these metrics matter a lot for permanent jobs. So I'll take it & celebrate :) 🎉

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@EikoFried

Eiko Fried

5 months

#MachineLearning models in mental health science "routinely achieve perfect performance [even in] large international multisite clinical trial [..] However, when that exact model was tested in truly independent clinical trials, performance fell to chance levels."

@danilobzdok

Danilo Bzdok

5 months

I cant wait to read this one! @mpwpaulus @joseph_kambeitz @JohnKrystal @PhilCorlett1 @koutsouleris

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@EikoFried

Eiko Fried

2 years

Magic mushrooms "liberate the entrenched depressed brain". The language of neuroimaging papers has become indistinguishable from homeopathy ads. Also, I absolutely love that Nature now publishes clinical trials without any info on sample size or effect size in abstract.

@neuroDaws

Richard E. Daws

2 years

Just out in @NatureMedicine . Psilocybin therapy liberates the entrenched depressed brain by increasing the global integration of functional networks. It has been brilliant to collaborate w/ @RCarhartHarris @ProfDavidNutt et al.

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@EikoFried

Eiko Fried

2 years

5/ Further, parts of the rebuttal reads like "how dare you criticize us—look at our h-index". If you use such arguments to try to convince fellow scientists about the merits of arguments in a debate, it is nothing short of admitting to having lost the argument.

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@EikoFried

Eiko Fried

3 years

Just finished my keynote at @conference_2021 on "Mental health: studying systems instead of syndromes". You can find slides & new preprint here: . Really enjoyed making a completely new presentation from scratch. 🧵

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@EikoFried

Eiko Fried

1 year

People say statistical modeling is boring but let me tell you #rstats just told me as part of model output that I am “on dangerous grounds” and I’ve never felt more alive.

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@EikoFried

Eiko Fried

5 months

In case you missed this: meta-analytic website with data of hundreds of clinical trials where you can conduct your own meta-analysis within a minute. A really remarkable tool of open scholarship.

@EikoFried

Eiko Fried

5 months

Did you know of this meta-analytic website by @pimcuijpers et al. featuring hundreds of RCTs? In the video I'll show researchers (part I) and clients (part II) how to run a systematic meta-analysis looking into the effect of CBT on depression in older adults within 1 minute.

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@EikoFried

Eiko Fried

5 months

"Psychological constructs and measures suffer from the toothbrush problem1: no self-respecting psychologist wants to use anyone else’s."

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@EikoFried

Eiko Fried

2 years

Excited about @AnnaWysocki3 's talk on "Statistical Control Requires Causal Justification"

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@EikoFried

Eiko Fried

3 years

Beautiful quote by the late Scott Lilienfeld on confusing biological mediation with biological etiology. Paying attention to this difference may resolve some apparent contradictions in views on mental health problems as "brain disorders".

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@EikoFried

Eiko Fried

3 months

In this new blog, I write about: 1. All that's wrong in academia—including bad papers, broken peer-review, the publishing industry, and precarious contracts. 2. How important it is *not* to become a cynic. 3. And my personal antidotes to cynicism creep.

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Antidotes to cynicism creep in academia » Eiko Fried

There are good reasons for cynicism creep — being disheartened about academia — but it's important we don't give in. I provide some antidotes.

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