Pieter Dorrestein @Pdorrestein1 Twitter profile

Last Seen Profiles

@CoachConClarke

@alfredodeMattos

@dad2ago

@imstephaniehope

@_TranceClassics

@ChaynFR

@StCatherineECSD

@AI2254351098516

@Lokolaleon

@PeterHerth

@quidd

@f_cybellekamba

@bautkendur

@francois_kabulo

@Dom_Mclawrence

@_SEAL_Org

@Ms_appletree

@Painrelifclinic

@markmessier

@yalphene

@Seasonsart

@Hi_LilTunechi

@Erwan_Ytube

@donsghae

@cfgaspar68

@donsghae

@vikingkvinde

@flyboyxun

@ACTYOLO

@VinceGray_

@flyboyxun

@zellerpd

@siphehlangu

@h_92al

@RiverPlateFR

@MeagherRacing

Pieter Dorrestein

@Pdorrestein1

5 months

I am so excited that @em_gentry1 ( @gentrylab ) paper on reverse metabolomics to discover molecules is published, a project started in 2018. She found many new lipids and bile acids in humans. (online ) What is reverse metabolomics?

Reverse metabolomics for the discovery of chemical structures from humans

Nature - A new discovery strategy, ‘reverse metabolomics’, facilitates high-throughput matching of mass spectrometry spectra in public untargeted metabolomics datasets, and a...

www.nature.com

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Pieter Dorrestein

@Pdorrestein1

6 months

Anyone doing metabolomics - this paper is worth a read. . This article corrects the literature and this was possible because the original article made their data public and was transparent. . Mistakes were made in relying 1/n

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Pieter Dorrestein

@Pdorrestein1

2 years

Here is a preview of our new tool, microbeMASST! Users can search for known/unknown MS/MS spectra against a database of bacterial/fungal monocultures and map the results into a phylogenetic/taxonomic tree! We are looking to expand our tree 🦠🍄🌳

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Pieter Dorrestein

@Pdorrestein1

3 months

Call to the microbiome community. We are building a collaborative microbial metabolite center (CMMC) knowledgbase resource to allow direct connection of microbiome derived molecules, their producers and activities. If you have published papers and want to add your 1/

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Pieter Dorrestein

@Pdorrestein1

3 years

Despite COVID lab members are getting wonderful job offers. If you want to be part of an exciting team working on important projects in small molecule mass spectrometry and metabolomics or interest in data, microbiome, nutrition, health, and other science, and have fun, please PM

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Pieter Dorrestein

@Pdorrestein1

4 years

I am a #proudPI , I just got word that one of my former grad students, who was the first in his large extended family to graduate, that he received his first award notice for an R01 as Assist. Prof. He almost dropped out in his second year of graduate school to support his family.

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Pieter Dorrestein

@Pdorrestein1

2 years

This is one of those papers that will transform how metabolomics data patterns at the spectral level within one project or repository can be analyzed. I anticipate this will become one of the most important tools we have to mine mass spec data. So proud of the team. So excited!

Ming Wang

@mingxunwang

2 years

The richness of untargeted mass spectrometry data is a blessing and a curse. We created MassQL to help mass spectrometry users to sift through this deluge of data and find exactly the molecules and classes of molecules they were looking for by defining their own MS data searches.

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Pieter Dorrestein

@Pdorrestein1

5 years

MASST = BLAST for MS/MS spectra against all tree main small molecule and metabolomics repositories ( @MetabolomicsWB , @MetaboLights and @GNPS_UCSD ) is submitted. Public data makes this possible and useful. Thanks to collaborators for making this a reality.

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Pieter Dorrestein

@Pdorrestein1

2 years

In mass spec. we often find metal adducts annoying, yet it is likely that many are biologically relevant. Heme, ATP, calcium or magnesium-dependent antibiotics, chalcophores, siderophores, zincophores are just the tip of the iceberg of small molecules that complex with metal in

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Pieter Dorrestein

@Pdorrestein1

1 year

I am honored and thankful for this award. It recognizes the labs effort to big data, open science but also training people receive to be able to build their own labs in industry and academia. This award is a reflection of current and former lab members and collaborators. Ty! 1/2

Fabian Rivera-Chávez (@fabianrchavez.bsky.social)

@FabianRChavez

1 year

Congratulations Pieter Dorrestein ( @Pdorrestein1 ) for being selected as 2023 Honorary Fellows of the Metabolomics Society! @MetabolomicsSoc

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Pieter Dorrestein

@Pdorrestein1

11 months

@jogleeson_ucsd I’ll have to check my lab as well. Curious if this is human subject approved and if all participants of the study have signed the form stating they will participate and if it explained how their human subject data will be used? @UCSanDiego

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Pieter Dorrestein

@Pdorrestein1

2 months

If you enjoy bile acids, then this will be a fun read and a resource for you. It shows that we can begin using untargeted metabolomics big data mining using a mass spec query language to discover new molecules in animals and humans.

The underappreciated diversity of bile acid modifications

Using mass spectrometry-based tools to mine public untargeted MS/MS data revealed the vastly underappreciated diversity of bile acids hidden in plain sight and led to the discovery of previously...

www.cell.com

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Pieter Dorrestein

@Pdorrestein1

3 years

Tomorrow morning our large scale swabbing project of the space station will be launched. Can’t wait to get the samples back and look at them by mass spec.

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Pieter Dorrestein

@Pdorrestein1

2 years

We just got a paper accepted that we started working on in 2016, started writing in 2018 and the first submission was in 2019. Fortunately no one’s career was dependent on this paper-as all the authors that led this work already have awesome jobs. #soproud of my team. More soon.

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Pieter Dorrestein

@Pdorrestein1

4 years

This will be a long thread to highlight the scientific journey a bit. The idea of this project started in 2013 as a small side project and it took a lot of developments and collaborations to make it possible. The paper is found here . We, as in Rob Knight

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Pieter Dorrestein

@Pdorrestein1

3 years

So proud of @AneBauermeister and @helenamrusso2 that tackled this review. It serves at a starting point/introduction to untargeted mass spectrometry analysis:tools in microbiome science. Many opportunities that remain in developing new or adapting existing tools from other fields

Nature Reviews Microbiology

@NatureRevMicro

3 years

Mass spectrometry-based metabolomics in microbiome investigations Dorrestein and colleagues review common forms of untargeted mass spectrometry and the types of data that can be obtained in the context of microbiome analysis

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Pieter Dorrestein

@Pdorrestein1

3 months

This paper is addressing a key challenge wrt the analysis of microbiome metabolomics data and that is - if a microbe can produce a molecule and which microbes can produce them? Tread 1/n

Simone Zuffa

@simonezuffa

3 months

microbeMASST is finally out on Nature Microbiology! Massive thanks to all the co-authors and cannot wait to see how the #microbiome community is going to use it

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Pieter Dorrestein

@Pdorrestein1

2 years

Love these amazing metabolites that microbes make.

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Pieter Dorrestein

@Pdorrestein1

4 years

I often wonder why this paper has not received the Nobel recognition? There are few developments that have had this much impact.

Basic local alignment search tool - PubMed

A new approach to rapid sequence comparison, basic local alignment search tool (BLAST), directly approximates alignments that optimize a measure of local similarity, the maximal segment pair (MSP)...

pubmed.ncbi.nlm.nih.gov

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Pieter Dorrestein

@Pdorrestein1

9 months

Today we got the first reviews back for a paper submitted in Oct 2022. It was worth the wait. All three revs said this paper defines the next few decades of research in the field as the speculative nature was well backed up. Ty for thoughtful #superreviews

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Pieter Dorrestein

@Pdorrestein1

11 months

Thanks, deeply honored and looking forward to be at next years meeting to give the honorary lecture. Have a great week at Niagara Falls!

Metabolomics Society

@MetabolomicsSoc

11 months

@Pdorrestein1 sends us some words for his honorary fellow award. Congrats!! #metsoc2023

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Pieter Dorrestein

@Pdorrestein1

3 years

We are recruiting research scientists. These are permanent career positions. The goal is to recruit someone to become the independent leader for the development of computational infrastructure for the community.

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Pieter Dorrestein

@Pdorrestein1

4 years

1/n Super excited about this work. We have had MASST (BLAST for molecules) for > 5 years however as there was not sufficient public data to search against it was not as useful at that time. As more data became available in @GNPS_UCSD / MassIVE @metabolights and @MetabolomicsWB

Nature Biotechnology

@NatureBiotech

4 years

Mass spectrometry searches using MASST

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Pieter Dorrestein

@Pdorrestein1

28 days

Excited that the perspective on bile acid modifications with @KnightLabNews is out. It is aimed to be a bit provocative. IMO - we need to rewrite and update all biochemistry textbooks. These are some of the most important molecules in biology. See

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Pieter Dorrestein

@Pdorrestein1

1 year

This paper is the brainchild of @TiagoLe88449658 and took him ~4 years to get to this point. It is super clever and links gene cluster families with molecular families from mass spectrometry data and (meta)genomics data.

Parra

@JonathanParraV

1 year

NPOmix: a machine learning classifier to connect mass spectrometry fragmentation data to biosynthetic gene clusters @TiagoLe88449658 @mingxunwang @jjjvanderhooft @AneBauermeister @Pdorrestein1 et al.

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Pieter Dorrestein

@Pdorrestein1

3 years

Experiment has been launched.

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Pieter Dorrestein

@Pdorrestein1

5 months

My view for today’s lunch. Grateful to be at @UCSanDiego where this is possible.

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Pieter Dorrestein

@Pdorrestein1

3 years

This is a wonderful collaboration with scientists across the world. It started with the interest of building @GNPS_UCSD and molecular networking for volatile molecules. We needed something that could scale to the analysis at the repository level.

Nature Biotechnology

@NatureBiotech

3 years

Auto-deconvolution and molecular networking of gas chromatography–mass spectrometry data

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Pieter Dorrestein

@Pdorrestein1

2 years

Ours first joint in person lab meeting with food and drinks since the start of the pandemic. This will be the format for our Monday group meetings in the foreseeable future. Glad this is possible all year in San Diego. @KnightLabNews @gilbertjacka

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Pieter Dorrestein

@Pdorrestein1

3 years

This is a remarkable paper on the discovery of an antifungal compound with a unique mode of action. The lipid structures they found are very unique. So many amazing molecules remain to be discovered. @GNPS_UCSD #lipidomics #metabolomics

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Pieter Dorrestein

@Pdorrestein1

3 months

In the last few years we discovered that bile acids are conjugated with other amines by microbes. See for initial discovery and kept dissolving them , , as did other labs

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Pieter Dorrestein

@Pdorrestein1

2 years

So lucky to be married to @KADorrestein . 20 years today. Can’t wait to see what the next 50 years hold for us.

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Pieter Dorrestein

@Pdorrestein1

1 month

Excited! - my daughter will be going to @ucdavis next year as a reagents scholar. The my do, however, grow up way way to fast and will miss her. But it’s only 8 - 9 hr drive away :)

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Pieter Dorrestein

@Pdorrestein1

2 months

Bile acids rule the world. I am becoming more convinced of this the more I learn about them.

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Pieter Dorrestein

@Pdorrestein1

2 years

It's that moment that you realize the need to reanalyze all the untargeted metabolomics data in the last decade because the knowledge of the community has been digitally captured and we can learn so much more from the data sets. Growth is so rapid that analysis cannot keep up🤩.

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Pieter Dorrestein

@Pdorrestein1

4 months

I am so excited that the paper led by @bittremieux on the creation of an open resource with nearest neighbor molecular network ms/ms library is out. when one does not get a match against existing libraries-this may help.

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Pieter Dorrestein

@Pdorrestein1

2 years

I just had a meeting to discuss progress on a project and it showed that it will be possible to do MS/MS analysis of hundreds of billions data points on a small device and also better distributed computing. It suggests that future annotations can become instantaneous. So fun!

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Pieter Dorrestein

@Pdorrestein1

1 year

It’s so wonderful to get a hard copy of this paper. Thanks @NatureBiotech

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Pieter Dorrestein

@Pdorrestein1

1 year

@GarciaLabMS My answer in terms of priorities is always 1) health, 2) family and friends, 3) then science. Projects can wait and will always be there. Although it is different for every person in the lab but the labs tends to push projects in bursts.

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Pieter Dorrestein

@Pdorrestein1

4 years

We introduce metadata repository analysis ReDU or

ReDU: a framework to find and reanalyze public mass spectrometry data

Nature Methods - Repository-scale reanalysis of public mass spectrometry-based metabolomics data is facilitated by the Reanalysis of Data User (ReDU) interface, a system that uses consistent...

www.nature.com

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Pieter Dorrestein

@Pdorrestein1

5 years

Thanks to all the co-authors for the effort. Several of whom we had met through twitter. One can see that this contribution is an international effort. @GNPS_UCSD is built by the community and for the community.

ChemRxiv

@ChemRxiv

5 years

Reproducible Molecular Networking Of Untargeted Mass Spectrometry Data Using GNPS by Mingxun Wang, Pieter Dorrestein ( @Pdorrestein1 ) & co-workers

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Pieter Dorrestein

@Pdorrestein1

4 months

If interested and want to learn LC-MS/MS metabolomics data processing, this is a workshop that will introduce you to a large number of state-of-the-art tools.

Tomáš Pluskal

@tomas_pluskal

4 months

This workshop at @IOCBPrague is going to be a great opportunity to learn about the latest developments in @mzmine_project and other #compMS tools!

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Pieter Dorrestein

@Pdorrestein1

27 days

There is currently not a single bile acid detection protocol that can fully capture the true diversity of bile acids, and, as a result, the ability to comprehensively detect and describe the extensive bile acid metabolic network represents a 21st century analytical challenge!!!

Nature Reviews Gastroenterology & Hepatology

@NatRevGastroHep

28 days

NEW! PERSPECTIVE The changing metabolic landscape of bile acids – keys to metabolism and immune regulation By @Pdorrestein1 @KnightLabNews & colleagues Readcube link

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Pieter Dorrestein

@Pdorrestein1

3 years

Currently we get on avg 5% (10-20%for human samples) annotation rates in untargeted #metabolomics . This wonderful collaboration with @boeckerlab provides a structural classification strategy leveraging classyfire ontology @WishartLab for MS/MS that do not have annotations. 1/2

Nature Biotechnology

@NatureBiotech

3 years

Systematic classification of unknown metabolites using high-resolution fragmentation mass spectra

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Pieter Dorrestein

@Pdorrestein1

10 months

Daughter coming in first #prouddad

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Pieter Dorrestein

@Pdorrestein1

4 years

If you are interested in learning about the applications of @GNPS_UCSD and #metabolomics and #massspectrometry or #naturalproducts - tune in for this exciting symposium organized by a world-wide consortium. It’s free to join.

GNPS - UC San Diego

@GNPS_UCSD

4 years

We are super excited about the awesome speakers for the 1st GNPS user meeting on Aug 26 (on zoom) with @kerrymcphail1 and @BeniddirM giving the two Keynote Lectures. Registration (free of charge) can be done here:

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Pieter Dorrestein

@Pdorrestein1

3 years

Spend some time w/o internet and phone. #California is so beautiful.

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Pieter Dorrestein

@Pdorrestein1

3 years

Dose 2, thanks @UCSanDiego

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Pieter Dorrestein

@Pdorrestein1

10 months

It been great to visit my family in the Netherlands - first time since start of COVID.

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Pieter Dorrestein

@Pdorrestein1

1 year

If you love #massspectrometry and #metabolomics , or #microbialmetabolites and want to be part of a fun team, please consider applying. also there are other positions - feel free to reach out via email for others.

Expired UC San Diego Jobs

Find Expired jobs for UC San Diego .

employment.ucsd.edu

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Pieter Dorrestein

@Pdorrestein1

10 months

@EMN_MetSoc 🙏 again for this honor. Looking forward to see all of you in Japan next year.

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Pieter Dorrestein

@Pdorrestein1

5 years

It is one of those days where I just realize just how awesome and creative the lab is, how amazing my co-workers and collaborators are, and how fortunate we are to be in a position where we are literally changing the way molecular analysis can be performed.

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Pieter Dorrestein

@Pdorrestein1

2 years

An awesome day with the group. Finally have an up to date group photo. Only ⁦ @mingxunwang ⁩ was missing. Don’t worry we will edit the phot so you will be part.

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Pieter Dorrestein

@Pdorrestein1

3 years

It has been one of those weeks. Just absolutely amazing creativity and results by lab members and by collaborators. This is why I love being a faculty member. The most impactful will be the Mass Spec Query Language that is being created by @mingxunwang and will transform analysis

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Pieter Dorrestein

@Pdorrestein1

8 months

Such crazy structures that @BeniddirM highlighted in his talk. #metabolomics has a lot of room for discovering new molecules. Yes this one one big small molecule!! The MS/MS is very rich.

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Pieter Dorrestein

@Pdorrestein1

4 years

Does anyone know if there is a large covid-19 proteomics signature? If so let me know as I would love to reposition the lab for large scale testing. @proteomics , @metabolomics

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Pieter Dorrestein

@Pdorrestein1

4 years

This is the first major tutorial with definitions and how to do molecualr networking created with and for the community. It is a good resource for people wanting a deeper understanding of molecular networking, terms used, what to pay attention to etc. Ty to all that contributed.

GNPS - UC San Diego

@GNPS_UCSD

4 years

We're so thankful to have a community that has been so welcoming of our tools. To make things a little more straightforward we are happy to share our latest protocols on Molecular Networking. Huge thanks to @allegraaron @em_gentry1 @kerrymcphail1 !

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Pieter Dorrestein

@Pdorrestein1

2 years

I vividly remember reading this article as a grad student and the only response I had was WOW! and I taught the Staudinger ligation and other click rxns to chem bio students. Congrats @CarolynBertozzi , Sharpless & Meldal with a well deserved #Nobel

Chemical remodelling of cell surfaces in living animals

Nature - Chemical remodelling of cell surfaces in living animals

www.nature.com

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Pieter Dorrestein

@Pdorrestein1

3 years

Wednesdays I meet with lab members individually - if they want to. It is always such a joy and I get so inspired by their accomplishments. Discussing science with the lab is one of my favorite things to do.

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Pieter Dorrestein

@Pdorrestein1

3 months

I just got a paper accepted and it is one that I am truly thrilled about. Stay tuned as it will be out in the next few months.

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Pieter Dorrestein

@Pdorrestein1

2 years

I am listening to @mingxunwang practice talk and if you ever want to know the amazing algorithmic contributions to MS/MS based annotations and molecular networking you should invite him to give a talk on this topic. He has an amazing ability to describe it in such a clear way.

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Pieter Dorrestein

@Pdorrestein1

4 years

This is a nice paper that describes the microbiome and metabolomics change early in life. In particular the bile acid differences. The authors also did a good job describing the data availability, including details on the metabolomics data.

Bile acids drive the newborn’s gut microbiota maturation

Nature Communications - Early postnatal colonization has been described to be critical for the long-term microbiota composition and health. Here, via multi-omics approach, the authors investigate...

www.nature.com

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Pieter Dorrestein

@Pdorrestein1

2 years

❤️ #SanDiego mornings.

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Pieter Dorrestein

@Pdorrestein1

4 years

If you are interested in metabolite annotation here is a nice workshop where you can learn from the developers and power users of @GNPS_UCSD , MSDIAL, @mzmine_project , @ms2lda , @boeckerlab and @WishartLab . @KatiHanhineva

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Pieter Dorrestein

@Pdorrestein1

2 years

We now have a molecular network of 13,003,591 spectral pairs. We now have to go beyond cytoscape to visualize and find ways to use the knowledge that can be gained from such a network #lovingscience

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Pieter Dorrestein

@Pdorrestein1

3 years

This is a wonderful paper that is possible because of community contributions to the @GNPS_UCSD libraries. Congrats to the authors.

Automatic Annotation and Dereplication of Tandem Mass Spectra of Peptidic Natural Products

The various bioactivity types and potencies of peptidic natural products (PNPs) are of high interest for the development of new drugs. In particular, the intrinsic antibiotic properties of PNPs...

pubs.acs.org

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Pieter Dorrestein

@Pdorrestein1

2 months

If you want to learn about new metabolomics tools and resources and perhaps interested in contributing this will be an educational webinar.

SPARC.science

@sparc_science

2 months

@dkNET_info will be hosting a webinar presented by Dr. Peter Dorrestein on Friday, February 23, 2024 to learn more about this useful resource "The Collaborative Microbial Metabolite Center"! #NIH_SPARC @Pdorrestein1

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Pieter Dorrestein

@Pdorrestein1

4 years

Discussing future operations and logistics for an ISS project in Houston. Can’t wait till it launches. Launch will likely be at the end of 2020 or 2021. Nice to bring a lab member along for the planning. You can see in the pic he is quite excited to be there.

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Pieter Dorrestein

@Pdorrestein1

3 years

2021 is finally here. May it be a healthy and happy one for everyone. 🙏 to everyone for getting through 2020. I am so amazed with the new scientific efforts in the lab that are in development. What is currently emerging suggests that 2021 will be a super exciting year.

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Pieter Dorrestein

@Pdorrestein1

3 years

This workshop will be a hands-on workshop (not series of lectures) on how to perform diet readout using untargeted metabolomics data in @GNPS_UCSD and source tracking using @qiime2 . No experience in metabolomics or microbiome or experts - all are welcome.

Nature Microbiology

@NatureMicrobiol

3 years

Join us a day early on the 16th Nov for a hands-on #microbiome and #metabolome workshop to understand #diet and #nutrition with @Pdorrestein1 and @KnightLabNews Find out more on our registration page:

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Pieter Dorrestein

@Pdorrestein1

3 months

This is a great review about the cancer microbiome . I remember when I was in grad school NCI had a statistic that 16% of all cancers are caused by microbes. HPV, F.nucleatum, and others were not even considered back then. This review gives a nice summary.

Intracellular bacteria in cancer—prospects and debates

npj Biofilms and Microbiomes - Intracellular bacteria in cancer—prospects and debates

www.nature.com

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Pieter Dorrestein

@Pdorrestein1

1 year

If you are interested in bioactive microbiome derived metabolites/ natural products and have ideas to discover them and their function, this NIH call is for you. Next deadline is June 22.

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Pieter Dorrestein

@Pdorrestein1

5 years

This paper describes how much the microbiome affects the molecular make up in 29 organs of mice and it gives insight into the types of metabolic transformations. Finally it shows the discovery of bile acids that are present when colonized with microbes.

Chemical Impacts of the Microbiome Across Scales Reveal Novel Conjugated Bile Acids

A mosaic of cross-phyla chemical interactions occurs between all metazoans and their microbiomes. In humans, the gut harbors the heaviest microbial load, but many organs, particularly those with a...

www.biorxiv.org

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Pieter Dorrestein

@Pdorrestein1

4 years

Today we had the -physically distanced- yearly #scrippspierswim . We missed ⁦ @BradMoore_SIO ⁩ @gilbertjacka ⁩, ⁦ @GerwickL ⁩, ⁦ @KnightLabNews ⁩ Fenical, Jensen, and other labs. Fastest swim= @julia_gauglitz ⁩, ⁦ @bittremieux ⁩ and ⁦ @amcaraballor ⁩

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Pieter Dorrestein

@Pdorrestein1

2 years

Are you looking for solutions that combine feature based molecular networking, ion identity mol networking, spectral matching, molecular formula and structural production etc here is a nice @ProjectJupyter notebook to merge. @GNPS_UCSD @tilmweber

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Pieter Dorrestein

@Pdorrestein1

9 months

Dio Siegel, @mraffatellu and I are recruiting a post-doc that is interested in synthesis of millions of molecules to discover microbiome derived metabolites/natural products associated with IBD. If you enjoy synthesis and want to learn data science pls send an email to us with CV

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Pieter Dorrestein

@Pdorrestein1

3 years

Thankful to everyone from the science that made this happen, to the development of distribution pipelines and to the people that are giving their time to give the vaccinations. @UCSanDiego @KADorrestein

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Pieter Dorrestein

@Pdorrestein1

4 months

Wed are my 1-on-1 meeting day. It was such an invigorating day today meeting with lab members - so much talent and creative ideas. It’s clear they are carving out a branch in what future metabolomics will look like.This is why I love being @UCSDSkaggsSOP for making this possible

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Pieter Dorrestein

@Pdorrestein1

5 years

Here we introduce a new metabolomics method to find small molecules that bind metals. and will give a brief background on the development of this as many developments came together at the right time. First was the science question by @mraffatellu 1/n

Native Electrospray-based Metabolomics Enables the Detection of Metal-binding Compounds

Metals are essential for the molecular machineries of life, and microbes have evolved a variety of small molecules to acquire, compete for, and utilize metals. Systematic methods for the discovery of...

www.biorxiv.org

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Pieter Dorrestein

@Pdorrestein1

5 months

On my way for a thesis defense. I love being on @Scripps_Ocean committees.

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Pieter Dorrestein

@Pdorrestein1

4 years

We have a newly minted PhD in the lab. So Proud.

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Pieter Dorrestein

@Pdorrestein1

4 years

I just got word that one of my former grad students got a fundable score for an R01. This is even more exciting to hear than receiving my own notice of award. #ProudPI

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Pieter Dorrestein

@Pdorrestein1

3 years

We are having a two half day Southern California mass spectrometry for early career scientists symposium. Open to all topics in mass spectrometry. Abstracts are due very soon but short. Anyone welcome to attend but to present you have to reside in Southern California.

MSACL

@MSACL

3 years

Call for Abstracts over a broad range of #MassSpectrometry topics from Early Career Southern California residents for symposium. #Genomics #Proteomics #Lipidomics #Metabolomics #Imaging #Exposome #Environmental #Clinical #Pharma #Therapeutics #Technology

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Pieter Dorrestein

@Pdorrestein1

4 years

This is Cryptomaldamide. We discovered this molecule a few years ago by MALDI in 2009, the paper was published in 2017 . Now we know with 100% certainty what enzymes make it. . Baby steps as we still dont know it's activity.

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Pieter Dorrestein

@Pdorrestein1

2 years

This will be tomorrow. Looking forward to it. I will describe the discovery of 170 new bile acids many made by the microbiome. There will be some surprising new ones. Can’t wait to show them.

Dr. Erin Baker

@ErinBakerIMS

2 years

We are really looking forward to this week's ILS webinar "Welcoming the New Year with New Lipids" on 1/27 at 10am EST. It will feature a short intro about ILS & upcoming events, followed by exciting talks by @Pdorrestein1 @KM_Hines & Xue Zhao. Plus it's open to anyone interested!

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Pieter Dorrestein

@Pdorrestein1

1 year

Had a fun trip with my nephew to Arizona

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Pieter Dorrestein

@Pdorrestein1

4 years

This project was 3.5 years in the making and established collaborations all over the world. It aims to make gcms analysis possible w less expertise, more reproducible, results sharable and to capture community knowledge and make it accessible to all-even labs with fewer resources

bioRxiv Bioinfo

@biorxiv_bioinfo

4 years

Algorithmic Learning for Auto-deconvolution of GC-MS Data to Enable Molecular Networking within GNPS. #biorxiv_bioinfo

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Pieter Dorrestein

@Pdorrestein1

7 months

The 15k swim took my daughter 3hrs, 49 min and 23 seconds. #proudDAD

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Pieter Dorrestein

@Pdorrestein1

9 months

I am honored to be listed with so many amazing analytical scientists. Thanks to the people that nominated me. Even more important thanks to the people that are/were part of the lab - their drive, creativity and interest in solving problems that led to this recognition. 🙏

The Analytical Scientist

@tAnaSci

9 months

The 2023 Analytical Scientist Power List has landed 🚀 This year, we’re recognizing those individuals whose excellence and impact has stood out over the past decade in analytical science. Find out who made the Power List >

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Pieter Dorrestein

@Pdorrestein1

3 years

There is so much potential in visualizing untargeted #metabolomics data as an MS/MS tree akin to sequence-based trees. Thanks to the authors and collaborators including @ernst_Madeleine , @jjjvanderhooft , @boeckerlab , @diaphanousd , @jo44atWID + others - see

Nature Chemical Biology

@nchembio

3 years

Qemistree, developed by @anupriya_trip @yoshikivb @KnightLabNews @Pdorrestein1 , uses fragmentation data to show molecular relationships as a tree and makes it possible to compare metabolomics data collected under different experimental conditions:

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Pieter Dorrestein

@Pdorrestein1

3 years

Our first in-person group meeting with masks and outside (and with some people remote that are in other parts of the world). Thanks to the vaccine developers, @UCSanDiego for an amazing rollout of the vaccination program. So good to see everyone.

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Pieter Dorrestein

@Pdorrestein1

4 years

So excited to see an amazing scientist being recognized with the knowles award. He is one of the best human beings I know and with a heart of a giant. Well done @RoySocChem

Professor Norberto Lopes | Jeremy Knowles Award winner 2020

We are proud to announce Professor Norberto Lopes as the Jeremy Knowles Award winner 2020. Read their full profile and share their achievement here.

www.rsc.org

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Pieter Dorrestein

@Pdorrestein1

3 years

So excited they are back. Missed them but COVID prevented them from being on campus. @belindasfamilia

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Pieter Dorrestein

@Pdorrestein1

6 years

Looking for people, experimental or computational omics, interested in having an impact on emerging Big Data algorithms and work with the Dorrestein () and Bandeira () labs. PM me or e-mail pdorrestein @ucsd .edu or bandeira @ucsd .edu.

The Dorrestein Lab - UCSD

Research Aims 1) Develop new mass spectrometry tools including bioinformatics tools 2) Understand Chemistry within microbes and how it impacts the ecosystem 3) Develop mass spectrometry approaches to...

dorresteinlab.ucsd.edu

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Pieter Dorrestein

@Pdorrestein1

2 years

If you find it hard to convert vendor mass spec/metabolomics data to #openscience formats or you find it complex to deposit data in the public domain and analyze with molecular networking. We now have the option of dragging and dropping your files in @GNPS_UCSD to make it easier.

Nature Metabolism

@NatMetabolism

2 years

Correspondence | @Pdorrestein1 , @mingxunwang & Nuno Bandeira present a quick-start interface that simplifies the analysis of untargeted metabolomics data through @GNPS_UCSD , and allows for community contributions in the spirit of #OpenData . #tbt

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Pieter Dorrestein

@Pdorrestein1

2 years

Wonderful #SanDiego bike ride.

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Pieter Dorrestein

@Pdorrestein1

3 years

Thanks @nchembio - it took a while to reach to me due to the delay of me a checking my mail in the pandemic. It was pleasant surprise to get two print copies. I still love reading on paper. I will pass them to @anupriya_trip as it is her fantastic work that is showcased.

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Pieter Dorrestein

@Pdorrestein1

2 years

Wishing a happy and healthy 2022.

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Pieter Dorrestein

@Pdorrestein1

9 months

#ProudPI

UC San Diego Skaggs School of Pharmacy

@UCSDPharmacy

9 months

Dr. Simone Zuffa, a postdoc in the @Pdorrestein1 lab, recently won both the Early Career Researcher Travel Award and the Best Presentation Award at Metabolomics 2023 ( @MetabolomicsSoc ). Swipe to read about Dr. Zuffa's presentation on microbeMASST. Congratulations, Dr. Zuffa!

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Pieter Dorrestein

@Pdorrestein1

2 years

We have been discussing pooled QC, in comparison to other forms of QC and downstream processing in metabolomics, it’s strengths and weaknesses in the lab but have found few benchmarking papers. Maybe twitterverse can help with IDing benchmarking papers.

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