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Nature Reviews Microbiology

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@NatureRevMicro
Nature Reviews Microbiology
1 year
Long COVID: major findings, mechanisms and recommendations @EricTopol @ahandvanish @LisaAMcCorkell @julialmv explore key findings, potential mechanisms, overlap with other conditions, potential treatments, and perspectives on long COVID research and care
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@NatureRevMicro
Nature Reviews Microbiology
7 months
The gut microbiota and its biogeography McCallum & Tropini discuss physical and biological factors affecting microbiota biogeography and organization at different scales. They overview the whole gut at the macroscale and zoom in to the scale of host and microbial interactions.
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@NatureRevMicro
Nature Reviews Microbiology
5 years
Scientists’ warning to humanity: microorganisms and climate change A group of leading microbiologists have come together to alert humanity that the central role and global importance of microorganisms in climate change biology must not be underestimated.
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@NatureRevMicro
Nature Reviews Microbiology
2 years
Microbiota succession throughout life from the cradle to the grave The human microbiota can undergo dramatic changes during different phases of life. In this Review, Knight & co discuss the microbiota successions that occur from the cradle to the grave.
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@NatureRevMicro
Nature Reviews Microbiology
1 year
Molecular mechanisms of antibiotic resistance revisited Blair, Webber and colleagues explore our understanding of the mechanisms of antibiotic resistance and how this information can aid in developing the next generation of antimicrobial therapies
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Nature Reviews Microbiology
6 months
Machine learning for microbiologists In this Review, Segata, Waldron and co discuss key concepts of machine learning that are relevant to microbiologists and provide them with a set of tools to apply machine learning in microbiology research.
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Nature Reviews Microbiology
9 months
Antibiotic perturbations to the gut microbiome Dantas & co. discuss factors that influence restructuring of the gut microbiome on antibiotic exposure, and explore promising therapeutics to minimize antibiotic-induced damage to the microbiome or restore the community structure.
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@NatureRevMicro
Nature Reviews Microbiology
4 years
Coronavirus biology and replication: implications for SARS-CoV-2 In this Review, Thiel and colleagues discuss the key aspects of coronavirus biology and their implications for SARS-CoV-2 infections as well as for treatment and prevention strategies.
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@NatureRevMicro
Nature Reviews Microbiology
4 months
SARS-CoV-2 biology and host interactions In this Review, @ProfVolkerThiel & colleagues summarize current knowledge of the SARS-CoV-2 intracellular life cycle and the molecular functions of viral proteins, as well as their interaction with the host cell.
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@NatureRevMicro
Nature Reviews Microbiology
1 year
📢SARS-CoV-2 variant biology: immune escape, transmission and fitness The authors discuss the mutations of SARS-CoV-2 variants, the impact of mutations on virus infectivity and transmissibility, and SARS-CoV-2 evolution in the context of immunity.
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@NatureRevMicro
Nature Reviews Microbiology
10 months
Plasmids, a molecular cornerstone of antimicrobial resistance in the One Health era Castañeda-Barba, Top & Stalder synthesize the recent literature on the ecological and evolutionary factors that determine the successful spread of plasmid-mediated antimicrobial resistance genes.
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Nature Reviews Microbiology
2 years
Life and death in the soil microbiome: how ecological processes influence biogeochemistry Sokol et al. illustrate how the ecological processes of living and decaying microorganisms can shape soil biogeochemistry
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@NatureRevMicro
Nature Reviews Microbiology
2 years
Alternative functions of CRISPR–Cas systems in the evolutionary arms race Staals, van der Oost and colleagues explore these non-canonical functions of CRISPR–Cas systems with relevant consequences for CRISPR-based genome editing applications
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Nature Reviews Microbiology
4 years
Innovations to culturing the uncultured microbial majority Ettema and colleagues highlight recent successes in culturing elusive lineages, innovative methods and key targets for future cultivation @Ettema_lab
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@NatureRevMicro
Nature Reviews Microbiology
2 years
Bacterial Biofilms This Focus issue explores insights into biofilm formation, gradients and consequences of heterogeneity in biofilms, tolerance of biofilms to antibiotics and host responses, and the spatial patterning of biofilms in infections
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@NatureRevMicro
Nature Reviews Microbiology
1 year
Bacterial defences: mechanisms, evolution and antimicrobial resistance Smith, Foster & co. discuss the mechanisms, evolution and clinical implications of bacterial protective strategies, new therapies for treating disease and how to minimize resistance.
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Nature Reviews Microbiology
2 years
Antigenic evolution will lead to new SARS-CoV-2 variants with unpredictable severity @pvmarkov , @ArisKatzourakis & Stilianakis argue that ongoing rapid antigenic evolution is likely to produce new variants that may escape immunity and be more severe.
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@NatureRevMicro
Nature Reviews Microbiology
10 months
📢The highly diverse antiphage defence systems of bacteria Georjon & Bernheim provide an overview of the molecular diversity of the most recently discovered bacterial antiphage defence systems and discuss their evolution and the ecological impact of their diversity.
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@NatureRevMicro
Nature Reviews Microbiology
5 years
Soil microbiomes and climate change Review: Jansson and Hofmockel explore the impacts of climate change on soil microorganisms and the potential ways that soil microorganisms can be harnessed to help mitigate the negative consequences of climate change.
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Nature Reviews Microbiology
1 year
Trichoderma: a multipurpose, plant-beneficial microorganism for eco-sustainable agriculture Woo et al. discuss the ecophysiology and diversity of Trichoderma and the complexity of its relationships in the agroecosystem environment
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@NatureRevMicro
Nature Reviews Microbiology
3 years
Mass spectrometry-based metabolomics in microbiome investigations Dorrestein and colleagues review common forms of untargeted mass spectrometry and the types of data that can be obtained in the context of microbiome analysis
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Nature Reviews Microbiology
8 months
📣The oral microbiome: diversity, biogeography and human health He & co. explore the structure and diversity of the oral microbiota, and they discuss the role of the oral microbiota in the pathology of both oral and systemic diseases. read it here:
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Nature Reviews Microbiology
2 years
Towards SARS-CoV-2 serotypes? In this Comment article Simon-Loriere & Schwartz discuss lines of evidence in support or against the concept of SARS-CoV-2 serotypes, and the implications of this classification.
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@NatureRevMicro
Nature Reviews Microbiology
7 months
Structural and functional diversity of type IV secretion systems Costa et al. review type IV secretion systems in Gram-negative bacteria, exploring their structures, specialized functions, biogenesis and localization.
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@NatureRevMicro
Nature Reviews Microbiology
2 years
Biology and evolution of bacterial toxin–antitoxin systems Van Melderen & colleagues review the biology and evolution of these small genetic elements, and discuss how genomic conflicts could shape the diversification of toxin–antitoxin systems
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@NatureRevMicro
Nature Reviews Microbiology
6 years
Bacterial adhesion at the single-cell level In this Review, Brun and colleagues summarize our understanding of the mechanisms governing bacterial adhesion at the single-cell level.
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Nature Reviews Microbiology
8 months
📢Disinfectants and antiseptics: mechanisms of action and resistance Maillard & Pascoe examine the mechanisms of action of biocides, as well as the bacterial intrinsic and acquired resistance to these biocides and its implications in environmental and clinical settings.
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Nature Reviews Microbiology
4 years
Next-generation physiology approaches to study microbiome function at single cell level @environmicrobio @microspietz @jay_zackary @msuchembiochem @Center4Biofilm @montanastate
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Nature Reviews Microbiology
6 years
Best practices for analysing microbiomes Knight et al. discuss best practices for performing a #microbiome study, including experimental design, molecular analysis technology, methods for data analysis and the integration of omics data sets @KnightLabNews
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Nature Reviews Microbiology
2 years
Soil microbiomes and one health Banerjee and van der Heijden outline the central role of the soil microbiome for one health and its detrimental or beneficial effects.
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Nature Reviews Microbiology
3 years
SARS-CoV-2 variants, spike mutations and immune escape Members of @CovidGenomicsUK (COG-UK) & co summarize SARS-CoV-2 spike mutations, their structural context and impacts on antigenicity, and discuss variants of interest or concern and vaccine efficacy.
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Nature Reviews Microbiology
4 years
The pan-immune system of bacteria: antiviral defence as a community resource Bernheim and Sorek present the ‘pan-immune system’ model in which bacteria employ horizontal gene transfer to access immune defence mechanisms encoded by closely related strains
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Nature Reviews Microbiology
2 years
Carbohydrate-active enzymes (CAZymes) in the gut microbiome Withers and colleagues discuss the vast diversity and activities of CAZymes and their potential applications.
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Nature Reviews Microbiology
5 months
Utilization of the microbiome in personalized medicine In this Review, Elinav and colleagues examine the advantages, challenges and future perspectives of utilizing microbiome data in personalized medicine for optimal patient care.
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Nature Reviews Microbiology
8 months
The rapid emergence of antifungal-resistant human-pathogenic fungi Lockhart & co. discuss the global emergence & spread of Candida auris, azole-resistant Aspergillus fumigatus & Trichophyton indotineae, all three emerging with a high rate of acquired resistance.
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Nature Reviews Microbiology
5 years
A brief guide to scientific writing If you missed my talk at #ECCMID19 but would like to get tips for how to write a review well (many points also apply to primary papers): 1. Tell a story 2. ABC of good writing style: accurate, brief, clear 1/3
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Nature Reviews Microbiology
2 months
Conservation and similarity of bacterial and eukaryotic innate immunity @aaronwhiteley and @hannahledvina review the similarities between eukaryotic and bacterial innate immunity, exploring conserved components, signalling and restriction mechanisms.
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@NatureRevMicro
Nature Reviews Microbiology
1 year
SARS-CoV-2 viral load and shedding kinetics Puhach, Meyer and Eckerle explore insights into what influences SARS-CoV-2 shedding, how this drives transmission and the tools available to measure this and determine infectiousness.
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Nature Reviews Microbiology
6 years
In this Review, Martens and colleagues discuss the complex interactions of commensal and pathogenic microorganisms with the intestinal mucosal barrier.
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Nature Reviews Microbiology
5 months
Alternative therapeutic strategies to treat antibiotic-resistant pathogens In this Review, MacNair, Rutherford & Tan explore the potential of non-conventional therapeutic strategies in the fight against antibiotic resistance.
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@NatureRevMicro
Nature Reviews Microbiology
3 years
Interactions between bacterial and phage communities in natural environments Chevallereau et al. review the roles of phage communities in controlling the population and evolutionary dynamics of bacterial communities
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@NatureRevMicro
Nature Reviews Microbiology
4 years
Proximate and ultimate causes of the bactericidal action of antibiotics How antibiotics actually kill bacteria is not entirely clear. Baquero & Levin reflect on this ultimate action of antibiotics, considering different mechanisms and modulating factors
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Nature Reviews Microbiology
4 years
Characteristics of SARS-CoV-2 and COVID-19 Zheng-Li Shi et al. summarize the exceptional amount of research that has characterized SARS-CoV-2 and COVID-19, discussing the emergence and virology of SARS-CoV-2 and the pathogenesis and treatment of COVID-19
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@NatureRevMicro
Nature Reviews Microbiology
3 years
Influenza virus and SARS-CoV-2: pathogenesis and host responses in the respiratory tract Schultz-Cherry, Thomas & co discuss influenza virus and SARS-CoV-2 pathogenesis, the host response in severe disease, epithelial repair and therapeutic interventions
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@NatureRevMicro
Nature Reviews Microbiology
5 years
Bacteria and archaea on Earth and their abundance in biofilms Flemming and Wuertz propose that biofilms are the most prominent and influential type of microbial life.
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Nature Reviews Microbiology
5 years
The ancestral and industrialized gut microbiota and implications for human health Sonnenburg and Sonnenburg explore whether individuals in the industrialized world may be harbouring a microbial community that is now incompatible with human biology.
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Nature Reviews Microbiology
4 years
The gut microbiota–brain axis in behaviour and brain disorders @liviahmorais , @HelixIV & Mazmanian discuss intricate and potentially important connections between the gut microbiota and brain, and possible contributions by the gut microbiota to behaviour
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Nature Reviews Microbiology
5 years
Origin of viruses: primordial replicators recruiting capsids from hosts In this Opinion article, Krupovic, Dolja and Koonin propose a new scenario for the origin of viruses based on primordial, selfish replicators acquiring structural proteins from cells
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Nature Reviews Microbiology
3 years
Bacterial motility: machinery and mechanisms Wadhwa & Berg review bacterial motility mechanisms and the current understanding of the molecular machines that enable bacteria to swim in aqueous media and move on solid surfaces @NavishWadhwa @MCB_Harvard
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Nature Reviews Microbiology
3 years
The human virome: assembly, composition and host interactions Liang and Bushman review research on the human virome and highlight studies that explore the assembly and composition of the virome as well as host–virome interactions in health and disease.
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@NatureRevMicro
Nature Reviews Microbiology
4 years
Origin and evolution of pathogenic coronaviruses Available free to read!
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Nature Reviews Microbiology
1 year
NEW Review🙌Forest microbiome and global change🌲 Baldrian & co. discuss the effects of global change on the forest ecosystem and its microbiome across different climatic zones, and present different strategies to reduce global change impact on forests.
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Nature Reviews Microbiology
6 months
Our December issue is now live! Read it here: The cover is inspired by two Reviews on the disruptive effects of antibiotic-induced damage to the gut microbiota.
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Nature Reviews Microbiology
3 years
Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis In this Review, Johansen and colleagues highlight genomic and phenotypic adaptation of Pseudomonas aeruginosa and the implications for infection management.
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Nature Reviews Microbiology
7 years
Molecular dynamics simulations of the crowded cytoplasmic environment in bacteria
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Nature Reviews Microbiology
4 years
The host-associated archaeome Moissl-Eichinger & colleagues discuss the diversity and potential roles of the archaea associated with protists, plants and animals, highlighting their potential roles in human health & disease @chmoei @SGribaldo
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Nature Reviews Microbiology
3 years
Revisiting the rules of life for viruses of microorganisms Correa et al advance a conceptual framework that recognizes virus–host interactions across a continuum of infection modalities
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Nature Reviews Microbiology
2 years
Microbiome-based therapeutics Sorbara & Pamer review the major bacterial phyla associated with health benefits and the potential of microbiome-based therapeutics, and the challenges confronting therapeutic development as well as the regulatory hurdles
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Nature Reviews Microbiology
3 years
Examining horizontal gene transfer in microbial communities Brito discusses methods to study how HGT shapes the function of natural microbial communities and explores questions to which some of these tools can be applied @ilanabrito123
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Nature Reviews Microbiology
5 years
Protein post-translational modifications in bacteria In this Review, Macek and colleagues introduce the major types of protein post-translational modifications in bacteria and discuss their roles in various aspects of bacterial cell biology.
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Nature Reviews Microbiology
4 years
Diversity within species: interpreting strains in microbiomes Bork, van Rossum et al. review advances & challenges that result from the use of metagenomic data to study within-species diversity @BorkLab @theavanrossum @pam_ferretti @OleksandrMaist2 @embl
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Nature Reviews Microbiology
5 years
Playing dead during phage infection #ResearchHighlight : A recent study reports that Cas13 induces a state of dormancy in bacteria, which inhibits viral replication and the rise of CRISPR-resistant phages. @alexjmeeske
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Nature Reviews Microbiology
4 years
Gut microbiota in human metabolic health and disease Fan & Pedersen discuss how the gut microbiota and derived microbial compounds may contribute to human metabolic health and to the pathogenesis of common metabolic diseases @Metabolcenter
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Nature Reviews Microbiology
2 years
Physical properties of the bacterial outer membrane Huang and colleagues discuss key molecular factors and interactions that give rise to the spatial organization, limited diffusivity and stress-bearing capacity of the outer membrane
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Nature Reviews Microbiology
6 years
A previously unknown electron-transfer pathway now reveals an energy-generation system used by bacteria in the human gut @nature @NatureNV :
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Nature Reviews Microbiology
2 years
Microbial diversity in extreme environments Shu and Huang explore the diversity, functions and evolution of bacteria and archaea inhabiting Earth’s major extreme environments
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Nature Reviews Microbiology
2 months
Effects of climate change and human activities on vector-borne diseases de Souza & Weaver examine various factors, such as climate change, human activities, and mobility, impacting the redistribution of vectors and vector-borne disease spread @wmarciels
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Nature Reviews Microbiology
2 years
Tolerance and resistance of microbial biofilms Ciofu and colleagues discuss our current understanding of the mechanisms of tolerance of biofilms to the immune system as well as tolerance and resistance to antimicrobials
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Nature Reviews Microbiology
5 months
🐝 The honeybee microbiota and its impact on health and disease Motta and Moran discuss how the gut microbiota influences honeybee biology and health, and explore environmental factors that can disrupt it and strategies for restoration. @ErickMotta19
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Nature Reviews Microbiology
6 years
The human skin microbiome by Allyson L. Byrd, Yasmine Belkaid & Julia A. Segre
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Nature Reviews Microbiology
2 years
Giant virus biology and diversity in the era of genome-resolved metagenomics In this Review, Schulz, Abergel and Woyke explore insights into the diversity, biology, biogeography and ecology of giant viruses provided by culture and genomic technologies.
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Nature Reviews Microbiology
7 years
💊💊 Today we launch a new series on antimicrobial resistance! Check out the first articles in the series here: 💊💊
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Nature Reviews Microbiology
6 months
Microbial murmurs — decoding hidden conversations between bacteria This Genome Watch highlights how genomic analyses revealed the widespread presence of a new class of bacterial signalling peptides that lack conventional characteristics.
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Nature Reviews Microbiology
3 years
Transmissibility and transmission of respiratory viruses Leung reviews transmissibility & transmission modes; viral, host & environmental determinants; non-pharmaceutical mitigation strategies & controversies over aerosol SARS-CoV-2 transmission
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Nature Reviews Microbiology
9 months
📣Insights into the assembly and regulation of the bacterial divisome Margolin & Cameron explore how the divisome of Escherichia coli is assembled and activated to modulate the division process, and discuss how the divisome machinery can be targeted for therapeutic purposes.
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Nature Reviews Microbiology
4 years
Gut microbial metabolites as multi-kingdom intermediates Bäckhed et al. discuss major microbial metabolites, highlight how they affect host health & provide a framework for integrating discovery-based metabolite studies with mechanistic work @BackhedLab
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Nature Reviews Microbiology
6 years
Why does the #microbiome affect behaviour? In this Opinion, Johnson and Foster explore the evolution of this relationship and propose that adaptations of competing gut microorganisms may affect behaviour as a by‑product, leading to host dependence.
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Nature Reviews Microbiology
6 years
Multidrug efflux pumps: structure, function and regulation This Review describes recent insights into the structure, function and regulation of efflux pumps.
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Nature Reviews Microbiology
5 years
Total synthesis of Escherichia coli with a recoded genome 🧬 @nature High-fidelity convergent total synthesis is used to produce Escherichia coli with a 61-codon synthetic genome that uses 59 codons to encode all of the canonical amino acids.
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Nature Reviews Microbiology
6 years
Targeting mechanisms of tailed bacteriophages In this Review, @StanBrouns and colleagues explore recent structural and mechanistic insights into the interaction of phage tails with receptors on the bacterial surface.
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Nature Reviews Microbiology
5 years
Extensive transmission of microbes along the gastrointestinal tract @eLife
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Nature Reviews Microbiology
6 months
Beneficial applications of biofilms Biofilms have diverse applications, from producing compounds to roles in agriculture and bioremediation. Gescher and colleagues provide an overview of the applications, challenges and future of beneficial biofilms.
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Nature Reviews Microbiology
6 years
Archaeal biofilm formation In this Review, Albers @Archaellum and colleagues explore the different stages of archaeal #biofilm development and highlight the similarities and differences between archaea and bacteria.
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Nature Reviews Microbiology
6 years
A gut bacterial pathway metabolizes aromatic amino acids into nine metabolites that circulate in their hosts @nature
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Nature Reviews Microbiology
7 months
Burkholderia pseudomallei and melioidosis Meumann et al. discuss B. pseudomallei virulence and interaction with the host, and examine the epidemiology of melioidosis, offering insights into diagnosis, treatment and prevention strategies for this disease.
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Nature Reviews Microbiology
2 years
Horizontal gene transfer and adaptive evolution in bacteria Arnold, Huang & Hanage discuss underlying theory used to infer the selective forces acting on transferred DNA and how they shape patterns of genomic variation
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Nature Reviews Microbiology
9 months
Co-evolution of immunity and seasonal influenza viruses Russell & colleagues explore the interplay between immunity evolution from previous infections or vaccination and the evolution of seasonal influenza viruses.
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Nature Reviews Microbiology
4 years
Microorganisms in the reproductive tissues of arthropods Perlmutter & Bordenstein discuss microbial symbionts in reproductive tissues of arthropods, their transmission modes, and physiological and evolutionary outcomes of their symbiotic relationships
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Nature Reviews Microbiology
4 years
Host–microbiota interactions in immune-mediated diseases Review: Kriegel & co discuss mechanisms through which the microbiota contributes to the predisposition, initiation and perpetuation of immune-mediated diseases, and explore therapeutic avenues.
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Nature Reviews Microbiology
5 years
Types and origins of bacterial membrane vesicles This Review provides an overview of different bacterial vesicle types, including classic outer-membrane vesicles and newly identified types that are induced by phage-derived autolysins.
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Nature Reviews Microbiology
1 month
Drug-resistant tuberculosis: a persistent global health concern Ahead of #WorldTBDay this weekend, Pai ( @paimadhu ) & co review the global landscape of drug-resistant TB, its causes, risk factors, impact, latest diagnostics, treatments, and more.
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Nature Reviews Microbiology
4 years
Evolutionary causes and consequences of bacterial antibiotic persistence Bakkeren, Diard & Hardt review evolutionary forces that favoured the development of persisters in populations & the consequences for spread of resistance & virulence determinants
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Nature Reviews Microbiology
1 year
📢Commensal bacteria fight colorectal cancer This study reports that some bacterial species of the Lachnospiraceae family can suppress colorectal cancer progression by modulating CD8+ T cell immune surveillance activity.
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Nature Reviews Microbiology
3 years
Featured article in the February issue: Gut microbial metabolites as multi-kingdom intermediates In this Review, Bäckhed and colleagues discuss the major classes of microbial metabolites
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Nature Reviews Microbiology
4 years
Diet, microbiome and immune homeostasis A Collection of Reviews from @NatureRevMicro , @NatRevGastroHep and @NatRevImmunol that explore the relationship between diet, the microbiome and immunity. Reviews are FREE to read for a limited time!
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Nature Reviews Microbiology
2 years
The biofilm life cycle: expanding the conceptual model of biofilm formation In this Review, Bjarnsholt and colleagues propose a revised conceptual model of the biofilm life cycle. @KarinSauer7 @PaulStoodley1 @metteburmolle @TBjarnsholt
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Nature Reviews Microbiology
4 years
Non-tuberculous mycobacteria and the rise of Mycobacterium abscessus In this Review, Johansen, Herrmann and Kremer discuss the infection process, host interactions, mechanisms of drug resistance and drug development
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Nature Reviews Microbiology
11 months
Drug delivery strategies for antibiofilm therapy Stride & colleagues discuss emerging drug delivery strategies to improve the clinical efficacy of antibiofilm agents, highlighting their current limitations and future prospects.
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