LatchBio @LatchBio Twitter profile

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LatchBio

@LatchBio

2 years

We just raised a $28 million Series A from Coatue and @Lux_Capital to build the AWS x GitHub for biocomputing. 1/N🔻

Announcing our Series A: Building the AWS x Github For Biocomputing

latch.bio

blog.latch.bio

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LatchBio

@LatchBio

2 years

Today we are thrilled to announce the Latch SDK, an open-source toolchain that any bioprogrammer can use to define serverless bioinformatics workflows with plain python and deploy an equivalent no-code interface. Request access: 🧵👇🏼 (1/N)

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LatchBio

@LatchBio

2 years

Alphafold predicts a protein's 3D structure from its amino acid sequence. Latch () now allows any scientist to run Alphafold with just a few clicks and view the 3D output right within the platform.

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LatchBio

@LatchBio

3 years

1/ Today we’re excited to unveil : an end-to-end CRISPR bioinformatics platform built on the cloud. We want to put the power of bioinformatics in the hands of every biologist.

CRISPR Bioinformatics in the Browser

wire #1 // the bottleneck in gene-editing, our Seed round from Lux Capital, and the plan to put the power of bioinformatics in the hands of every CRISPR biologist.

blog.latch.bio

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LatchBio

@LatchBio

1 year

We are thrilled to announce a complete redesign of the Latch Platform! Our goal was to create an interface that would be more familiar for bioinformaticians while visually integrating with other software in their lab. LatchBio Me: the next-gen user interface for biocomputing.

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LatchBio

@LatchBio

2 years

Today, we’re excited to release Latch Verified Bulk RNA-seq - a curated, end-to-end RNA-seq pipeline that converts FastQ files to count matrices, to differentially expressed genes, to top enrichment pathways. Run it now with a few clicks at 🧵

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LatchBio

@LatchBio

2 years

Just published a “Solutions” tab + 2 case studies to better reflect how our partners are leveraging Latch to accelerate their research. 👇🧵 (1/N)

LatchBio

Harmonize your Wet and Dry Lab.

latch.bio

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LatchBio

@LatchBio

2 years

Introducing Pollock: a single-cell browser for live transformations on massive datasets. - Browse, edit, or create annotations - Subcluster and re-do dim reduction - Visualize differential gene expression - Track all transformations and analyses Use it now! (⅛)

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LatchBio

@LatchBio

7 months

It was great to host Sam Altman last night at the LatchBio HQ to talk to Stanford students about responsible building, challenging giants, and advancing humanity.

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LatchBio

@LatchBio

2 years

Two Boston events coming up next week. In collaboration with @NucleateHQ and @bitsinbio . Whether you prefer a casual meetup or an intense hack day, we would love to see you there! RSVP to hang: Apply to hack:

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LatchBio

@LatchBio

3 months

We are thrilled to announce that LatchBio is officially HIPAA compliant!⚕️Check out our Trust Center here: If you would like to learn more about HIPAA, how to sign a BAA, or hear more details on how Latch approaches data security, please let us know via…

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LatchBio

@LatchBio

11 months

How it started vs. how it's going 💁‍♀️ #SynBioBeta 2022 ➡️ 2023 Come stop by the booth for a product demo (and to check out the glow up✨)

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LatchBio

@LatchBio

2 years

For months, the Latch Platform has been the easiest way to run AlphaFold2. But a frequent ask we got was “can it go faster?” Now it can! ColabFold from Sergey O has 10x faster inference on small proteins and is now freely available at . How it works... 🧵

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LatchBio

@LatchBio

1 month

Today we’re introducing four revolutionary product redesigns. A New Latch Data, Workflows, Registry, and Pods. New Data, New Workflows... Are you getting it?! These are not four separate redesigns. We're replacing *the entire platform* with just an AI Chatbot, and we are…

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LatchBio

@LatchBio

2 years

We are excited to announce Latch Coin, a quantum enabled biocomputing protocol for the federated exchange of DNA and other sequence information.

LatchCoin

We use quantum computing enabled cross chain decenralized blockchain native protocols to solve P=NP and enable linear time sequence alignment for construction of the human pangenome.

latch.cash

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LatchBio

@LatchBio

2 years

We are excited to release the Latch API. Use it to programmatically access your suite of serverless bioinformatics workflow and integrate off-the-shelf or custom tools with your own codebase and scripts. Try it out now at: (1/N)

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LatchBio

@LatchBio

2 years

Great time this weekend at the Boston Biocomputing Hackathon! It was inspiring to see the results of bringing together talented bio-developers and directing them towards a problem — creating workflows for scientists to process biological data. Two of our favorite projects:

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LatchBio

@LatchBio

3 years

2/ Modern biology requires wrangling massive datasets. Yet talented bioinformaticians are so scarce that biologists often wait weeks for simple data analysis. This utterly cripples the research cycle, massively delaying breakthrough cures for cancer, heart disease, and aging.

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LatchBio

@LatchBio

2 years

Today, we’re introducing Latch Pods: A supercomputer in the cloud for biodevelopment. A pre-configured environment with Jupyter Labs and RStudio ready to go! 1/N

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LatchBio

@LatchBio

6 months

We’ve noticed wet <> dry lab teams need a database to collaborate in. Easy to use for scientists, programmatically queryable for biodevelopers. Today we’re excited to announce Latch Registry: An integrated database for multi-omics.

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LatchBio

@LatchBio

2 years

Congratulations to our CEO @alfredoandere for being selected as a “Founder to Watch” for the @pillar_vc and @petribio ’s Founder-Led Biotech Week! Check out the spotlight and the rest of the winners at

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LatchBio

@LatchBio

2 years

Announcing the SDK Slack Community🎉 This is the next generation of biocomputing engineers building software for biology in labs and companies across the world. Join us to build no-code interfaces for bioinformatics with Python. DM @kenbwork for an invite.

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LatchBio

@LatchBio

2 years

We have combined Bulk RNA-seq and differential expression into a single end-to-end workflow to enrich genes or transcripts across custom conditions directly from the sequencer...

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LatchBio

@LatchBio

2 years

We're excited to announce the open sourcing of Structured CSV (SCSV), a spec and parser for embedding complex typed JSON values inside CSV files and other user-facing data formats. Read more here: (1/N)

Structured CSV

How to parse a CSV into form inputs // Static typing, JSON-formatted data, and in-memory backtracking recursive descent parser // Github, NPM, Spec, and Licensing.

blog.latch.bio

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LatchBio

@LatchBio

1 year

10 days until the AI x BIO HACKATHON with Lux Capital, OpenBioML, HuggingFace and LatchBio! Fine tune an existing model, or train one from scratch. Datasets, pre-trained models, sponsored GPU's & API's/PlugIns provided. SIGN UP AT

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LatchBio

@LatchBio

2 years

Workflows in the wild (Github and custom front-ends) often lack test data that scientists can use to quickly check functionality. All workflows on the Latch Platform () now have test data, allowing anyone to test them in 30 seconds.

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LatchBio

@LatchBio

2 years

Building tools for biologists is hard. Biodevs lack the resources to release workflows with a cloud-deployed GUI. The result is fragmented and inaccessible tools. Latch SDK makes workflow development faster AND automatically creates a cloud-deployed GUI. Today we go 2.0… (1/N)

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LatchBio

@LatchBio

2 years

Thanks to @HummingbirdVC , @haystackvc , @bwhite5290 , and @fiftyyears for joining the round. 2/N

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LatchBio

@LatchBio

2 years

LatchBio is a repository of versioned no-code tools, managed computing infrastructure and collaborative data hub tailor made for biological research. 6/N

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LatchBio

@LatchBio

2 years

Automation, next-generation sequencing and multiplexed assays have drowned the modern biologist in a deluge of complex and unwieldy data. Transforming this flood of information into human interpretable insights is expensive and painful. 3/N

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LatchBio

@LatchBio

2 years

Yet talented bioinformaticians, a rare breed of SWE x scientist, are far and few between. Furthermore, the need for data versioning, reproducible computation and data infrastructure becomes an enormous engineering project, requiring an army and fortune to build. 5/N

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LatchBio

@LatchBio

2 years

Scientists often need to run dozens of pipelines at the same time, making interfaces without batch-mode very tedious. All workflows in the Latch Platform () now have batch-mode built in. Letting anyone import a CSV and launch hundreds of workflows at once.

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LatchBio

@LatchBio

3 years

5/ We also want to thank our friends, family, and our amazing investors for supporting us this far—we genuinely couldn't have done it without you. Special thanks to @Lux_Capital , @FiftyYears , @Haystackvc , @GeneralCatalyst for leading our seed round and pushing this forward.

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LatchBio

@LatchBio

1 year

Shiny is a powerful R package that enables creation of interactive web applications using R code. Now, you can easily host RShiny Apps on Latch! 🧶

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LatchBio

@LatchBio

2 years

Usage of our platform has grown since our $5M seed from Lux in October. We’ve partnered with The Innovative Genomics Institute, BitBio, EligoBio, Geltor, and dozens of leading bio labs across the globe to speed up their time to the clinic. 9/N

Innovative Genomics Institute

@igisci

2 years

When the IGI Clinical Laboratory began sequencing positive #COVID tests for variants, we had huge amounts of data and no spare time! The solution: automation. With the help of @LatchBio , we've processed 1000+ samples with no code or infrastructure needed.

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LatchBio

@LatchBio

3 years

3/ lets biologists run CRISPR computational analysis in their browser without a single line of code. The flow is simple: upload sequence data, find a workflow, run a workflow on your data, and visualize the results.

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LatchBio

@LatchBio

2 years

DO NOT FORGET TO LOVE!! 👬👭👫🧑‍🤝‍🧑🧍🐻💕Happy Valentimes y’alls!

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LatchBio

@LatchBio

2 years

Biologists are often more comfortable in the wet lab than in front of a computer terminal and lack the background in software to solve this problem for themselves. 4/N

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LatchBio

@LatchBio

2 years

How do we use great ideas from computing to build a platform for biology? Let's deconstruct the components of a modern biocomputing stack. (1/n)

Down the Biocomputing Stack ~ Motivation

repurposing great ideas from computing to build for biology

blog.latch.bio

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LatchBio

@LatchBio

2 years

Thanks to our amazing team, as well as @brandonreeves @brandonwhite @aashaysanghvi_ @semil @velvetatom @moxon @sethbannon @ayushnoori @ChaChaChavey for your support.

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LatchBio

@LatchBio

2 years

The power of Latch is now available through the command line. Excited to release the Latch CLI. Transfer files to the cloud with “cp”, explore your data with “ls”, run workflows with “execute”, and open the results with “open”. And much more.

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LatchBio

@LatchBio

2 years

This is an opportunity to lay the foundational bricks of an enormous and generational project with an amazing team. If you are interested in building at the intersection of computing and biology, come join us. N/N

LatchBio

Harmonize your Wet and Dry Lab.

latch.bio

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LatchBio

@LatchBio

2 years

Announcement: Tomorrow’s Software x Bio Hackathon will be hosted at the Cambridge Marriott on the 2nd floor. Please arrive at 12pm sharp. We’re psyched to see you there. 🚀 P.S. a few spots are still open. Apply here:

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LatchBio

@LatchBio

2 years

Latch Verified now has three Bulk RNA-seq workflows that should be simple to use, flexible, and easy to scale. 1. Bulk RNA-seq generates count matrices 2. DESeq2 finds and displays top differentially expressed genes 3. Enrichment Analysis! Lastly…

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LatchBio

@LatchBio

2 years

We hope your holidays are filled with cheems.

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LatchBio

@LatchBio

3 years

4/ Today, our waitlist opens to the public. To our initial users at Berkeley, Stanford, & MIT. Thank you. Your feedback has been tremendous. To all the CRISPR labs, LatchBio is free for the academic community, and we’ll be onboarding new labs over the coming weeks.

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LatchBio

@LatchBio

2 years

Hosting a meetup at our office tonight for a new community called Bits in Bio ( @bitsinbio ). It's mostly software x bio people in industry and academia. Pizza & drinks included. 🍕 🍹 DM us if you’d like to come!

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LatchBio

@LatchBio

3 years

6/ And this is just the start. These problems are prevalent across all of biotech. We envision building one of the great software companies of the 21st century, laying the bricks for the biocomputing revolution.

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LatchBio

@LatchBio

2 years

Integrative Genomics Viewer (IGV) is a great tool for visualizing and exploring genomics data. But any scientist that has used it knows that it can be a hassle to get it up and running. The Latch Platform now supports native IGV by double clicking any FASTA or BAM files.

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LatchBio

@LatchBio

2 years

Biologists can directly process their data with a catalog of intuitive interfaces and collaborate with shareable visualizations. Bioinformaticians can use our developer toolkit to dynamically generate interfaces and portable cloud deployments of their local scripts. 7/N

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LatchBio

@LatchBio

2 years

Introducing Latch Pods, ColabFold, SDK map tasks, and celebrating our partnership with Funga

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LatchBio

@LatchBio

10 months

RFdiffusion generates novel proteins which bind to target molecules. With just a few clicks, @LatchBio now allows any scientist to run RFdiffusion and view the 3D output right within the platform. Easily launch a new notebook with RFdiffusion (with GPU) today on Latch Pods ➡️…

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LatchBio

@LatchBio

2 years

Latch’s industry adoption is complemented by a swelling community of academic researchers, making their research accessible and reproducible with frontend interfaces. 10/N

Abdullah Al Nahid

@abdnahid_

2 years

Perform de novo genome assembly from @nanopore reads with FREE GPU (🤯) on the cloud without any hassle of software installation! At @LatchBio , I've integrated the "shasta" long read assembler and here's what the interface looks like👇 A mini thread:

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LatchBio

@LatchBio

2 years

We are cultivating the strongest technical and creative talent in the biotech space, building a team of polymathic talent who have eschewed derivative trading and ad optimization for the mission of accelerating fundamental science. 11/N

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LatchBio

@LatchBio

2 years

The entire organization benefits from versioned and reproducible program execution and traceable data provenance. 8/N

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LatchBio

@LatchBio

1 year

Do you use EC2 instances? Today we see biotechs using EC2 for a few core applications: exposing Jupyter notebooks or RStudio, hosting applications with RShiny or Dash Plotly, or simply providing a remote environment with more powerful compute. The problem is EC2 is expensive,…

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LatchBio

@LatchBio

2 years

We have finalized a huge milestone in our collaboration with @GeneEditingDE ! LatchBio is now the official platform to leverage DECODR, their leading industry tool for analyzing CRISPR Sanger sequencing data. Use it now at and learn more below👇 (1/N)

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LatchBio

@LatchBio

2 years

The Latch Platform now lets scientists sync/mount Amazon S3 buckets, serving as a better interface for their S3 data (e.g. auto FastQC) and allowing them to use those files as inputs to the 30+ bioinformatics workflows available. Try it out at .

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LatchBio

@LatchBio

1 year

Introducing Pod Templates 🚀🚀 Life-saving science demands reproducible analyses. But setting up an environment with 500+ dependencies, 96 cores, and 1000 GiB of RAM is no trivial task.

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LatchBio

@LatchBio

2 years

MAGeCK is a toolkit for interpreting relevant genes from CRISPR/Cas-9 screens built by @davidliwei and . We've worked with them to make it more accessible. An interface for the tool is now freely available at in the browser. (1/N)

Welcome to Wei Li lab

Children's National Hospital / George Washington University

weililab.org

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LatchBio

@LatchBio

2 years

The next Biocomputing Journal Club will be led by the talented @paulinapaiz02 from @GladstoneInst . She will walk us through Enformer, a deep learning model to model gene expression. Sign up here (wouldn't want to miss this one ;) ~ . August 24th, 10 AM PT

Biocomputing Journal Club

Next session is August 24th. Paulina Paiz will be presenting ~ "To continue exploring language models, I want to present Enformer, a model that improves gene expression prediction by leveraging the...

docs.google.com

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LatchBio

@LatchBio

2 years

Don't miss the "Data Platforms in Biotech" panel at 4pm ET where our CEO @AlfredoAndere , @falexwolf , and Elizabeth Hudson will discuss how the large influx of biological data is changing the data infrastructure landscape. Attend for free!

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LatchBio

@LatchBio

2 years

The Latch Platform now lets scientists collaborate under a team workspace. They can share a data storage, debug executions as a team, and see the outputs of each other's workflows. Check it out at

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LatchBio

@LatchBio

11 months

LatchBio is live at #SynBioBeta2023 Day 2! 🧬 Stop by our booth for a product demo, new company merch, or to talk with one of our teammates about how we’re building the data infrastructure for the biocomputing revolution.

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LatchBio

@LatchBio

2 years

Aditya Dalal made a deployed interface for the Allen Cell & Structure Segmenter toolkit! The purpose of this library is to provide 3D segmentation of intracellular structures in fluorescence microscopy images.

GitHub - adidalal/latchbio-wf: Allen Cell Segmenter x LatchBio

Allen Cell Segmenter x LatchBio. Contribute to adidalal/latchbio-wf development by creating an account on GitHub.

github.com

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LatchBio

@LatchBio

2 years

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LatchBio

@LatchBio

2 years

By serving as a bioinformatics CRO for our partners over the last months and processing >1,000 Bulk RNA-seq samples, we identified the common reasons why existing solutions fall short: 1. Lack of simplicity 2. Lack of flexibility 3. Lack of scale We have a solution...

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LatchBio

@LatchBio

2 years

Happy to announce our partnership with @igisci . 🎉 We've helped them automate Clinical Covid Testing for 1000+ patients to date. Read more in the case study!

Innovative Genomics Institute

@igisci

2 years

At the IGI, we’ve moved towards automation of clinical #COVID19 genomic testing thanks to partners like @LatchBio . Read more 🧵👇

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LatchBio

@LatchBio

2 years

CRISPResso2 is a tool that analyzes genetic editing experiments. It was built by @KendellClement @lucapinello . We have published it to to make it accessible to biologists in the browser. (1/N)

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LatchBio

@LatchBio

3 years

Thanks! Very excited to be working with @BrandonReeves08 and the whole team at @Lux_Capital to lay the foundation of the biocompute revolution.

Brandon Reeves

@breeves08

3 years

"The goal of the Latch Project™ is to build and disseminate the data infrastructure of the biocomputing revolution" Congrats to @AlfredoAndere , @kenbwork , @kylegiff . Looking forward to working with all of you.

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LatchBio

@LatchBio

10 months

We're hosting a @bitsinbio happy hour at our SF HQ tomorrow! Come meet other engineers, scientists, founders, etc. building software tools to accelerate scientific discovery. 🧬 RSVP HERE ➡️ ⬅️

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LatchBio

@LatchBio

1 year

See you at #SynBioBeta2023 ! 🧬 Latch is hosting a fireside chat with @LauraDeming , a panel on data infrastructure for biocomputing with @ElsieBio and @ManifoldBio , and an exhibit booth to demo our platform.

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LatchBio

@LatchBio

9 months

GPU is now available in Latch Pods! Each GPU pod comes with 15 cores, 60 GiB RAM, and 1 GPU at a cost of $0.0832/minute. Get instant access to a GPU now at .

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LatchBio

@LatchBio

2 years

@DeepMind recently changed the model's weights from a non-commercial to a fully open license. We are very excited for the possibilities that this unlocks.

Sergey Ovchinnikov 🇺🇦

@sokrypton

2 years

"The AlphaFold parameters are made available under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) license" 🙂 (thanks to @BrianWeitzner for alerting me)

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LatchBio

@LatchBio

2 years

Nick Rosenau and Nishant Jha created an interface to generate a Latch Workflow From a bioRxiv url!

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LatchBio

@LatchBio

2 years

Select developers can now upload their bioinformatics workflows to Latch and gain: a type safe user interface, scalable production cloud deployment , and a reliable and versioned way to run your code. No compute environments. No infrastructure. (3/N)

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LatchBio

@LatchBio

2 years

MultiQC is a tool that creates a quality control (QC) report over sequencing files. The new "FastQC + MultiQC" workflow allows scientists to point at any folder containing FASTQ files and it will automatically produce a report, which can be visualized from within the platform.

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LatchBio

@LatchBio

2 years

Resource Management: There are several task decorators that easily allow you to define the resources available at runtime. From 2 CPUs and 4 GBs of memory to 31 CPUs, 120 GBs of memory and 1 GPU (24 GBs of VRAM, 9,216 CUDA cores) to easily handle all processing needs. (8/N)

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LatchBio

@LatchBio

28 days

We are entering a fourth agricultural revolution. Today, companies like Metagen are using computers and genetic engineering to grow enhanced crops with greater yield and less resources.

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LatchBio

@LatchBio

7 days

Metagen is an Australian biotech helping farmers optimize their soil’s microbiome – increasing crop productivity and profitability. We were humbled during yesterday’s webinar when Chris highlighted how they use Latch as their “unified platform” for agricultural analytics.

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LatchBio

@LatchBio

2 years

This week our CTO @kenbwork gave a talk outlining the role that @flyteorg plays in Latch's infrastructure, how it solves concrete problems in biocomputing and open source contributions our eng team has made to the project. Check out the recording here .

Workflow Orchestration for Biocomputing ~ adopting Flyte @ LatchBio

Kenny Workman, co-founder and LatchBio CTO, introduces LatchBio, gives an overview of ML needs in the Biotech industry, explains how they rely on Flyte for w...

www.youtube.com

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LatchBio

@LatchBio

2 years

Intuitive Parameters: The Latch SDK offers a rich set of traditional and biological data types as inputs. The function header is compiled into a type safe UI, with components corresponding to each parameter. (5/N)

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LatchBio

@LatchBio

2 years

Each parameter can be configured by altering its corresponding component (swapping a number field with radio options for common integer values), adding documentation (such as labels and help tooltips), and by changing its order and grouping on the page. (7/N)

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LatchBio

@LatchBio

2 years

Three commands… —and your workflow is on Latch. $ pip install latch $ latch init package_name $ latch register path_to_workflow_directory (4/N)

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LatchBio

@LatchBio

9 months

We're hiring an ambitious Sales Development Representative to join our team in SF. This role is crucial: you'll be an expert in predictable lead generation, finding market opportunities, executing outreach campaigns, and systematically booking meetings. Find out more at…

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LatchBio

@LatchBio

2 years

If you use AlphaFold on Latch, please cite the original paper and give all due credit to the authors - We hope its release on facilitates wider use among biologists.

Highly accurate protein structure prediction with AlphaFold

Nature - AlphaFold predicts protein structures with an accuracy competitive with experimental structures in the majority of cases using a novel deep learning architecture.

www.nature.com

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LatchBio

@LatchBio

2 years

We are calling this Web4.0 - the collision of biocomputing and blockchain - and we are pivoting all of our underlying infrastructure to this protocol.

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LatchBio

@LatchBio

2 years

Thanks to all the participants for joining us and to our co-organizer @NucleateDojo and bib. More hackathons coming soon to a city near you.

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LatchBio

@LatchBio

2 years