Kevin Ng @KevinWNg Twitter profile

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Kevin Ng

1 year

Excited to share our work on B cells in lung cancer, published today in @Nature !

Antibodies against endogenous retroviruses promote lung cancer immunotherapy

Nature - In lung adenocarcinoma, antibodies against endogenous retroviruses promote anti-tumour activity, and expression of endogenous retroviruses can predict outcomes of immunotherapy.

www.nature.com

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Last Seen Profiles

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Kevin Ng

@KevinWNg

3 years

just when you thought academic CVs couldn’t get any more competitive

@mnitabach.bsky.social

@mnitabach

3 years

OK a post-doc won the gold medal in the women's Olympic cycling road race!!!

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Kevin Ng

@KevinWNg

3 years

the sheer confidence of people on twitter

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Kevin Ng

@KevinWNg

6 years

i think my data may be trying to tell me something? #science

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Kevin Ng

@KevinWNg

3 years

My beloved ELISA wash bottle is absolutely going into my thesis acknowledgements

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Kevin Ng

@KevinWNg

2 years

The newly-established Kassiotis lab western blot wall of shame

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Kevin Ng

@KevinWNg

4 years

me taking snacks back to my desk after every seminar

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Kevin Ng

@KevinWNg

3 years

@AJMooreHealth It would be hilarious if it weren’t so serious

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Kevin Ng

@KevinWNg

3 years

It starts.

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Kevin Ng

@KevinWNg

4 months

Every scientist deserves a sexy shirtless statue

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Kevin Ng

@KevinWNg

2 years

In celebration of #DayOfImmunology , I’m a doctor!

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Kevin Ng

@KevinWNg

2 years

Really excited to see this paper out! A pan-coronavirus vaccine could be our way out of this and future pandemics, and @nikifaulkner and I think that a S2-based vaccine could do just that

SARS-CoV-2 S2–targeted vaccination elicits broadly neutralizing antibodies

Vaccination against the S2 subunit of SARS-CoV-2 induces antibodies in mice that neutralize a broad range of human and animal coronaviruses.

www.science.org

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Kevin Ng

@KevinWNg

2 years

thesis: submitted

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Kevin Ng

@KevinWNg

4 years

Our paper on cross-reactive coronavirus antibodies - rare in adults, but more common in children - is now published in @ScienceMagazine !

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Kevin Ng

@KevinWNg

2 years

Off to New York! Looking forward to starting my postdoc with @victora_lab 🔬

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Kevin Ng

@KevinWNg

4 months

glycosylation in action

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Kevin Ng

@KevinWNg

2 years

Finishing the PhD with the best people ❤️🎉🥂

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Kevin Ng

@KevinWNg

4 months

Excited to be starting as a @CancerResearch Fellow later this year, studying germinal centre B cells in colorectal cancer

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Kevin Ng

@KevinWNg

4 years

my paper made it into @nytimes and i can die happily now

The Children Never Had the Coronavirus. So Why Did They Have Antibodies? (Published 2020)

A provocative study suggests that certain colds may leave antibodies against the new coronavirus, perhaps explaining why children are more protected than adults.

www.nytimes.com

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Kevin Ng

@KevinWNg

4 years

Our latest preprint is now out! We were surprised that antibodies specific for common cold coronaviruses were capable of binding and neutralising (at least in vitro) conserved epitopes from SARS-CoV-2:

Pre-existing and de novo humoral immunity to SARS-CoV-2 in humans

Several related human coronaviruses (HCoVs) are endemic in the human population, causing mild respiratory infections[1][1]. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the etiologic...

www.biorxiv.org

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Kevin Ng

@KevinWNg

1 year

no! more! qPCRs! ✊🏼

Senator Tammy Nichols

@nichols_senator

1 year

Today I introduced a bill to ban all messenger ribonucleic acid technology (mRNA) in the State of Idaho, and we passed the Freedom in Education Savings Account out of the Senate Education Committee to fund students and not systems, putting families in control over their ed $.

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Kevin Ng

@KevinWNg

11 months

When I was in my PhD program I went to parties every week and I did just fine 💁‍♀️

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Kevin Ng

@KevinWNg

2 years

“four years”, five years later

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Kevin Ng

@KevinWNg

6 years

playing my fave game of “can i find my virus before the freezer starts aggressively beeping at me” #science

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Kevin Ng

@KevinWNg

2 years

hi dad! congrats, and stuff

UBC Science

@ubcscience

2 years

Dr. Raymond Ng of UBC Computer Science is a newly elected Fellow to the Royal Society of Canada (RSC). Congrats, Raymond! @UBC_CS @UBCMDS

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Kevin Ng

@KevinWNg

4 years

Today has been a good science day!

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Kevin Ng

@KevinWNg

4 years

My first PhD paper is out in @eLife ! Plenty of T cells, retroelements, and PD-L1:

Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist

An ancient integration of an endogenous retroelement in the gene encoding PD-L1 is exapted to generate a soluble form that antagonises the suppressive function of the membrane-bound form.

elifesciences.org

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Kevin Ng

@KevinWNg

3 years

getting a head start on thesis writing

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Kevin Ng

@KevinWNg

8 months

grad school

Ichigo Niggasake

@SomaKazima

8 months

A mood

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Kevin Ng

@KevinWNg

3 years

Baking weekends with @Nigella_Lawson

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Kevin Ng

@KevinWNg

2 months

Our puppy turns one today!

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Kevin Ng

@KevinWNg

1 year

2023 goals

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Kevin Ng

@KevinWNg

4 years

Our work describing a novel interferon-inducible ACE2 transcript is now out in @NatureGenet !

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Kevin Ng

@KevinWNg

2 years

every time a new variant hits

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Kevin Ng

@KevinWNg

3 years

What determines how children respond to the common cold? In our new paper in @MedCellPress , we study antibody responses in children to common cold coronaviruses:

Favorable antibody responses to human coronaviruses in children and adolescents with autoimmune...

Deakin et al. examined the antibody response to the common-cold coronavirus HCoV-OC43 and cross-reactive response to SARS-CoV-2 in pre-COVID-19 pandemic sera from JIA, JDM, and JSLE patients. They...

www.cell.com

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Kevin Ng

@KevinWNg

1 year

i’m sorry but WHAT

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Kevin Ng

@KevinWNg

3 years

The joys of British cuisine - fried potatoes with a side of fried potatoes

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Kevin Ng

@KevinWNg

2 years

Excited to share our latest preprint, in which @nikifaulkner and I explore S2 immunization as a pan-coronavirus vaccine approach

Broad human and animal coronavirus neutralisation by SARS-CoV-2 S2-targeted vaccination

Several common-cold coronaviruses (HCoVs) are endemic in humans and several variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have emerged during the current Coronavirus...

www.biorxiv.org

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Kevin Ng

@KevinWNg

4 years

An updated version of our manuscript on antibody cross-reactivity between seasonal coronaviruses and SARS-CoV-2 is now online:

Pre-existing and de novo humoral immunity to SARS-CoV-2 in humans

Several related human coronaviruses (HCoVs) are endemic in the human population, causing mild respiratory infections[1][1]. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the etiologic...

www.biorxiv.org

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Kevin Ng

@KevinWNg

1 year

when i try and fold a fitted sheet

Tom and Lorenzo

@tomandlorenzo

1 year

Florence Pugh in Valentino Couture at the #Oscars #Oscars95 . More red carpet later on our site.

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Kevin Ng

@KevinWNg

11 months

(like honestly, fuck this idea that 24/7 work in grad school is a good thing)

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Kevin Ng

@KevinWNg

11 months

Meet Clovis the shiba!

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Kevin Ng

@KevinWNg

2 years

when cell rejects my paper

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Kevin Ng

@KevinWNg

2 years

New Year’s Eve, PhD student budget edition

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Kevin Ng

@KevinWNg

3 years

Our paper on antibody cross-reactivity between SARS-CoV-2 variants is now out in @eLife !

Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2...

Heterotypic immunity, the ability of immunity induced by one SARS-CoV-2 variant to protect against another, is asymmetric, with the UK (B.1.1.7) variant, eliciting weaker heterotypic immunity than...

elifesciences.org

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Kevin Ng

@KevinWNg

3 years

Had a great time presenting some of our recent findings on B cell responses in lung cancer. Stay tuned for the preprint coming very soon!

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Kevin Ng

@KevinWNg

6 years

guess who just passed their comps #officiallyaphdstudent

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Kevin Ng

@KevinWNg

4 months

Happy New Year from Madrid!

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Kevin Ng

@KevinWNg

6 months

Bach, science, and @SchmidtFellows

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Kevin Ng

@KevinWNg

2 years

It’s been a fun 5 years!

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Kevin Ng

@KevinWNg

3 years

no! no! no you can't!

The Atlantic

@TheAtlantic

3 years

"Although scientists don’t quite understand why, kids seem to be naturally protected. As a result, you can think of your son or daughter as an already vaccinated grandparent," @ProfEmilyOster writes:

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Kevin Ng

@KevinWNg

2 years

So in 2022 I get to play my absolute dream concerto with orchestra and I can’t wait 🍾

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Kevin Ng

@KevinWNg

7 years

@Point_Mutation We add a pipette tip to our SDS loading buffer, just because nobody can remember a time there hasn't been a pipette tip in there.

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Kevin Ng

@KevinWNg

9 months

Breakfast view

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Kevin Ng

@KevinWNg

7 months

Ready for 3 days of B cells

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Kevin Ng

@KevinWNg

2 months

Sometimes microscopy is worth it

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Kevin Ng

@KevinWNg

3 years

Thrilled to have contributed to such a cool study - the SARS-CoV-2 spike recruits biliverdin to evade binding of monoclonal and polyclonal sera

SARS-CoV-2 recruits a haem metabolite to evade antibody immunity

The coronaviral spike is the dominant viral antigen and the target of neutralizing antibodies. We show that SARS-CoV-2 spike binds biliverdin and bilirubin, the tetrapyrrole products of haem metabo...

www.medrxiv.org

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Kevin Ng

@KevinWNg

4 years

Another day, another preprint! Our work on interferons and a novel isoform of ACE2 is now online:

Tissue-specific and interferon-inducible expression of non-functional ACE2 through endogenous...

Angiotensin-converting enzyme 2 (ACE2) is an entry receptor for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), as well as a regulator of several physiological processes. ACE2 has...

www.biorxiv.org

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Kevin Ng

@KevinWNg

3 years

Excited to share our data on antibody cross-reactivity to emerging SARS-CoV-2 variants, comparing D614G and B.1.1.7 convalescent sera

Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2...

We examined the immunogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant B.1.1.7 that arose in the United Kingdom and spread globally. Antibodies elicited by B.1.1.7...

www.biorxiv.org

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Kevin Ng

@KevinWNg

2 years

10 days to thesis submission, and I’ve proofread it so many times none of my figures mean anything anymore

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Kevin Ng

@KevinWNg

2 years

we are all juanita

Cincinnati Zoo

@CincinnatiZoo

2 years

Anyone else already giving up on their New Year's resolutions? In case you aren't sure what you're looking at, Juanita the armadillo is napping in her exercise wheel.

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Kevin Ng

@KevinWNg

4 years

putting “coronavirus antibody researcher” on my cv asap

The Crick

@TheCrick

4 years

📝 @nikifaulkner and @KevinWNg have used a test they developed to show that some antibodies that match up with the SARS-CoV-2 spike protein aren’t just found in #COVID19 patients, and might also be found in people who have had certain colds in the past.

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Kevin Ng

@KevinWNg

2 years

When your dad is a "leading academic data leader" but you still don't know how to use Excel properly

UBC DSI

@UBCDSI

2 years

Dr. Raymond Ng, Director of @UBC #DataScience Institute and Professor of @UBC_CS named to @magazine_cdo 2022 list of leading academic data leaders! Congrats Dr. Ng!

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Kevin Ng

@KevinWNg

2 years

Cost so far for my 6-month visa extension: £494 application fee £121 NHS fee £125 scheduling fee for a mandatory in-person appointment £51 to “scan my documents” Will we break the £1000 mark?

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Kevin Ng

@KevinWNg

4 years

The true spirit of Christmas

Adam(Alaa) Bujairami

@AdamBujairami

4 years

A possum broke into an Australian bakery and ate so many pastries it couldn't move. This is how they found him.

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Kevin Ng

@KevinWNg

2 years

We’re in the Guardian 😮

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Kevin Ng

@KevinWNg

2 years

me as i enter my last month before thesis submission

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Kevin Ng

@KevinWNg

3 years

Easily my favourite scientific metaphor

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Kevin Ng

@KevinWNg

3 years

turns out grad school hasn’t changed one bit

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Kevin Ng

@KevinWNg

3 years

um

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Kevin Ng

@KevinWNg

3 years

💉💉💉

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Kevin Ng

@KevinWNg

10 months

pupdates

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Kevin Ng

@KevinWNg

2 years

Post-thesis submission trip booked ☀️

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Kevin Ng

@KevinWNg

3 years

Our latest preprint on antibody responses to endemic coronaviruses in children is now out!

Favourable antibody responses to human coronaviruses in children and adolescents with autoimmune...

Differences in humoral immunity to coronaviruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), between children and adults remain unexplained and the impact of underlying...

www.biorxiv.org

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Kevin Ng

@KevinWNg

3 years

😮

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Kevin Ng

@KevinWNg

7 months

when your puppy really wants to help with the grant writing

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Kevin Ng

@KevinWNg

3 years

A real in-person conference!

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Kevin Ng

@KevinWNg

3 years

Easily the coolest coronavirus-related finding I've had the chance to be involved in!

Science Magazine

@ScienceMagazine

3 years

. @TheCrick , @KCLImmunoMicro , @UCLInfectImm scientists have identified another potential target for neutralizing antibodies on the #SARSCoV2 Spike protein that is masked by metabolites in the blood. New in @ScienceAdvances : #COVID19

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Kevin Ng

@KevinWNg

1 year

Some nice coverage of our paper from the @BBC !

BBC Science News

@BBCScienceNews

1 year

Million-year-old viruses help fight cancer, say scientists

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Kevin Ng

@KevinWNg

2 years

The Final Lab Meeting

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Kevin Ng

@KevinWNg

6 months

when your dog agrees to a selfie

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Kevin Ng

@KevinWNg

5 years

It’s 5:41, but I’m off to Amsterdam to talk about T cells!

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Kevin Ng

@KevinWNg

3 years

🎉

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Kevin Ng

@KevinWNg

1 year

become your model organism

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Kevin Ng

@KevinWNg

2 months

As biologists, we all have an obligation to counter the misuse of biology in the name of transphobia

Cell Press

@CellPressNews

2 months

@CellCellPress It includes a Commentary from 24 transgender (and/or family of trans) scientists discussing the experiences of sex and gender minorities in STEMM and offering actions to help build a more inclusive academia and produce more accurate and rigorous science:

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Kevin Ng

@KevinWNg

9 months

Guess what movie I’m seeing

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Kevin Ng

@KevinWNg

3 years

Contrary to what this image may suggest, I studied neither smart nor hard during my undergrad... 😬

University of British Columbia

@UBC

3 years

Want to study smarter, not harder for finals this term? Read on for study strategies—based in neuroscience research—from a @UBCPsych prof:

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Kevin Ng

@KevinWNg

6 months

Best venue for performing solo Bach

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Kevin Ng

@KevinWNg

4 months

happy 2023 to me, I’ve clearly past my peak

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Kevin Ng

@KevinWNg

5 years

After spending most of my life on the flow cytometer, it's lovely to actually see my cells!

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Kevin Ng

@KevinWNg

7 months

talking about my favourite b cells

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Kevin Ng

@KevinWNg

3 years

considering changing my phd topic immediately

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Kevin Ng

@KevinWNg

3 years

😮

Nature Index

@NatureIndex

3 years

The 5 most talked-about scientific papers of November 2020 in the Nature Index journals @LucyvanDorp @f_heppner @KevinWNg

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Kevin Ng

@KevinWNg

2 years

My B cells have made it to Edinburgh even if I haven’t - huge thanks to @bsicongress for being so flexible!

James Harker

@HarkerImmuno

2 years

@KevinWNg beautiful talk @bsicongress #BSI21 . Tumour GCs. Cracking. Wishing you were here to discuss in person though. Likewise all those other @London_immuno committee members currently stuck in London or somewhere on the way to Edinburgh.

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Kevin Ng

@KevinWNg

1 year

😮 Resurrection of endogenous retroviruses during aging reinforces senescence

Resurrection of endogenous retroviruses during aging reinforces senescence

Liu and colleagues uncover the ways in which derepression of human endogenous retrovirus triggers cellular senescence and tissue aging; the findings provide fresh insights into therapeutic strategies...

www.cell.com

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Kevin Ng

@KevinWNg

1 year

A @victora_lab rite of passage

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Kevin Ng

@KevinWNg

3 years

Fond memories of a particular PhD interview incident at the Pasteur

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Kevin Ng

@KevinWNg

3 years

A great study from my labmate on SARS-CoV-2 integration - they find that host-virus chimeric reads, proposed as evidence of genomic integration, are likely sequencing artefacts

SARS-CoV-2-host chimeric RNA-sequencing reads do not necessarily signify virus integration into the...

The human genome bears evidence of extensive invasion by retroviruses and other retroelements, as well as by diverse RNA and DNA viruses. High frequency of somatic integration of the RNA virus severe...

www.biorxiv.org

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