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Paired with a corresponding gel-assisted chemical etching process, new flexible microneedles enable customizable, minimally invasive observation of soft, dynamically moving tissues. Learn more in this week’s issue of Science Advances:

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Science Advances

@ScienceAdvances

2 years

Tiny Brazilian frogs’ inner ear canals are too small to help them balance well, explaining why they are clumsy jumpers.

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Scientists discovered two #snake specimens preserved in Late Cretaceous amber from Myanmar, including what they say is the oldest known baby fossilized snake. These samples suggest snakes were more ecologically diverse than previously thought

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7 months

Women leave academia at higher rates than men at every career stage, and attrition is especially high among three groups: tenured faculty, women in non-STEM fields, and women employed at less prestigious institutions, according to a new analysis.

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7 years

Over 9.1 billion tons of plastic have been made and most of it thrown away

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4 years

Scientists have fabricated a deformable, hydrogel-based sensor directly onto a continuously inflating and deflating pig lung, demonstrating a new 3D printing method that estimates surface motion in real time.

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6 years

In the latest issue: A closer look at the retention rate of LGBQ college students in STEM degrees, new insights into the dwarf planet Ceres' evolution, the discovery of a new subauroral structure, and more

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1 year

Using mRNA, researchers have developed a promising approach for the intracellular delivery of genes in the eye, which may have the potential to prevent vision loss for inherited retinal diseases. Learn more in this week’s issue of Science Advances:

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2 years

Scientists propose the Human Proteoform Project—an initiative to describe a complete set of protein forms expressed from the approximately 20,000 genes encoded in the human genome—as a critical next step in disease research.

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1 year

A new #genetics study suggests a link between mitochondrial dysfunction and RNA editing in schizophrenia.

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2 years

A new modeling study suggests #ClimateChange may have already doubled the likelihood of catastrophic flooding in California, and future warming will likely result in even greater increases in #flood risk.

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2 years

New research on ants has produced a treasure map for finding hidden biodiversity among other small-range species. Learn more in this week’s issue of Science Advances:

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3 years

Tiny, candy-like 3D models could enable blind students to visualize molecules and other scientific imagery with their mouths.

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2 years

Scientists have unearthed evidence for a major earthquake that struck Chile’s Atacama Desert about 3800 years ago, triggering not only a tsunami, but serious social disruption.

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11 months

Vessel noise during oceanic transportation is known to disrupt natural marine life processes. Now, researchers have identified multiple strategies to reduce the area and severity of ships’ impact on marine life. Learn more in this week’s issue:

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1 year

New research finds that musical training can make older adults better listeners by preserving youthful brain activity patterns. Learn more in this week’s issue of Science Advances:

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4 months

Inspired by the human retina, researchers have created an #imaging sensor to detect all visible colors in the spectrum. The device could lead to more efficient and intelligent imaging methods.

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4 years

Impulsive behavior is associated with the structural integrity of a connection between a major dopamine hub in the midbrain and a decision-making center in the forebrain, a new study reveals.

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1 year

Americans with kindred political ideologies share similar patterns in neural activity, according to a new neuroimaging study.

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2 years

A new dataset of morphological features from all major lineages of early reptiles, early synapsids, and their close relatives shows how climate crises shaped the early evolution of reptiles.

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1 year

New research could offer deeper insights into fibroblasts’ role in the foreign body response to implanted medical devices. Read more in this week’s issue of Science Advances:

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3 years

Only 1.5% to 7% of the modern human genome is uniquely human, according to an analysis of Neanderthal, Denisovan, and human genomes.

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4 years

Scientists staged a multi-player gambling game and scanned participants’ brains, which illuminated a network of neural structures involved in learning from other people that—it turns out—is separate but linked to how we learn from our own experience.

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11 months

New medicine-carrying nanoparticles improved physical and psychological symptoms in mice with inflammatory bowel disease.

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1 year

Researchers have developed a glucose-responsive microneedle patch that enables closed-loop delivery of both insulin and glucagon for #diabetes treatment. Learn more in this week’s issue of Science Advances:

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11 months

New research uses a #MachineLearning approach to reveal insights into the interplay between biological, phenotypic, and environmental factors contributing to premature and healthy pregnancies. Learn more in this week’s issue of Science Advances:

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2 years

Conventional super-resolution microscopy often fails to fully capture small details. By combining metal-induced energy transfer and super-resolution microscopy, researchers can clearly image sub-cellular structures in 3D. Read more in this week's issue:

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2 years

In a new Editorial, Science Advances Editor Ali Shilatifard argues that long-term investment in basic research by the U.S. government will remain essential as the nation continues recovering from the #COVID19 pandemic.

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3 years

Lacking access to biosafety level 3 laboratories, Chilean scientists have developed a pseudotype of the SARS-CoV-2 virus that enables them to safely study neutralizing antibodies.

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1 year

Researchers have investigated the dispersion patterns of Vibrio cholerae, the causative agent for #cholera , and reveal that chaotic transport of micro-swimmers can arise in simple unsteady flows. Learn more in this week’s issue of Science Advances:

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1 year

A new software tool, named INTERSTELLAR, can decode data values encoded in theoretically any type of sequencing read and translate them into sequencing reads of another structure of choice. Learn more in this week's issue:

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3 years

Two specific histamine receptors may play an important role in the way the human body responds to exercise, according to a new study that could inform the development of exercise-based therapies.

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4 months

Researchers analyzed isotopes from a 14,000-year-old female woolly mammoth tusk to reconstruct her past movements and used ancient DNA from her and other mammoths to determine their sex and relatedness. Read more in this week’s issue of Science Advances:

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2 years

A microalgae-based drug delivery system, nanoparticles in the treatment of #osteoporosis —all new in this week’s Science Advances:

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1 year

New research highlights root fungi’s critical role in #biodiversity and #ClimateChange mitigation. Learn more in this week’s issue of Science Advances:

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2 years

With fewer natural predators to contend with, Kenyan chameleons introduced to Oahu, Hawaii, display flashier color signals. Learn more in this week’s issue of Science Advances:

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1 year

Tears reveal more than just emotion. This week, researchers find extracellular vesicles in tears act as immune effectors, maintain retinal homeostasis, and regulate inflammation, revealing rich bioinformation that offers value beyond the ocular system.

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4 years

New research suggests that dwindling oxygen in the world’s oceans may have been partially responsible for the end-Triassic mass extinction event, one of the “Big Five” extinctions in Earth’s history.

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4 months

Biomedical engineers introduce a paper-like, battery-free sensor that uses #AI to assess wound healing. The sensor enables a 97% accuracy in early detection of adverse events, such as infection, and could improve wound care management. @TeeResearchGrp

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9 months

A new conformable ultrasound breast patch enables precise deep breast tissue scanning that could enable a user-friendly, noninvasive approach to early #BreastCancer detection.

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2 years

Researchers have cataloged silk gene sequences to measure the mechanical, thermal, structural, and hydration properties of the dragline silks of 446 species of spiders. Learn more in this week’s issue of Science Advances:

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11 months

Biomedical engineers introduce a paper-like, battery-free sensor that uses #AI to assess wound healing. The sensor enables a 97% accuracy in early detection of adverse events, such as infection, and could improve wound care management. @TeeResearchGrp

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3 years

Machine learning techniques are helping researchers to understand the complex set of conditions within the tumor microenvironment and the dynamic changes it undergoes in response to therapies.

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6 months

Researchers have created a soft #robotic platform for minimally invasive procedures that can both stabilize the entrance to the heart and guide existing surgical instruments. Learn more in this week's issue of Science Advances:

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2 years

A new cross-disciplinary study establishes the immense complexities of basement membranes and their impact on human health. Learn more in this week’s issue of Science Advances:

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7 years

Scientists tracked 13 pumas at their feeding spots for years. Ask them about it during a Facebook Live on 10/19!

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2 years

Scientists have developed the first fully automated system for recognizing wild primate behavior using audio and visual signatures.

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2 years

Modern humans and Neanderthals may have coexisted in Europe 54,000 years ago, a stratigraphic timeline of the Tibetan Plateau’s rise, and a sustainable alternative to mining—all new this week in Science Advances:

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4 months

Researchers have designed an electronic weight loss pill that can induce the illusion of fullness by stimulating the stomach’s “stretch” receptors through vibration, according to a new study in pigs.

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1 year

By studying human dermal fibroblast-grown de novo microtissues, as depicted here, researchers shed light onto the complex relationships between cells and their extracellular matrix during tissue growth. Read more in this week’s issue of Science Advances:

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9 months

New research highlights the critical role of the insulin superfamily in maintaining cognitive health. Learn more in this week's issue of Science Advances:

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3 years

A genomic analysis of virtually all cichlid species in Lake Tanganyika reveals that these fish have an incredibly plastic system for sex determination, which can change more frequently than scientists have observed in any other organism to date.

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3 years

In chemistry, atom-mapping is a laborious task. But a new method has proved a remarkably fast and accurate alternative and may provide the missing link between data-driven and rule-based approaches for many chemical reaction tasks.

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3 years

AstraZeneca and the University of Oxford developed their #COVID19 vaccine based on a chimpanzee adenovirus called ChAdOx1 described in this May Science Advances paper, in which a vaccine that encoded the ChAdOx1 MERS spike protected macaques from MERS.

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1 year

Early dinosaurs’ dental form suggests dietary diversity may have been key to their dominance, according to a new study.

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4 years

Indoor air quality is important to human health, yet the ways in which chemicals interact with indoor surfaces are not fully understood. New research is taking a closer look. Read that study and others now out in Science Advances:

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2 years

New research on hallucinogenic drug experiences, fMRI-based machine learning models, and more—all new in this week’s Science Advances:

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1 year

A new wearable “sweatainer” introduces a sweat collection method that aids the collection of multiple, independent pristine sweat samples during vigorous physical activities. Learn more in this week’s issue of Science Advances:

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7 months

New research suggests the history of range expansions of modern humans, and not just natural selection, have deeply influenced the patterns of Neanderthal ancestry. Learn more in this week's issue of Science Advances:

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1 year

Researchers have determined that specific single-nucleotide mutations in our ancestral genomes created thousands of gene regulatory elements orchestrating the expression of genes in the brain of modern humans. Learn more in this week's issue:

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1 year

A new #PhosphorescenceImaging method uses organic nanoparticles to detect tumor metastases at an early stage. The method could improve the detection of metastasis and improve #cancer patient outcomes.

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4 years

Scientists have used a new high-speed, in vitro selection method to isolate 9 antibody-like proteins that bind to the #SARSCoV2 virus—4 of which also exhibited neutralizing activity—within 4 days, according to a new study.

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1 year

Researchers have designed a microneedle patch that allows for more precise targeting of localized diseases and holds clinical potential as a general cell delivery platform. Learn more in this week’s issue of Science Advances:

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3 years

#COVID19 lockdowns and China’s early 2020 spring, local insect population declines, and a novel hydrogel—all new in this week’s Science Advances:

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2 years

Elkhorn coral’s reproductive genesis enabled researchers to study how somatic mutations (DNA alterations to non-germline cells after conception) transfer to offspring. Learn more in this week’s issue of Science Advances:

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2 years

Extinct megatooth sharks, commonly known as megalodons, may have been one of the most dominant apex predators in the ancient marine world. Learn more in this week’s issue of Science Advances:

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2 years

A new study reveals that elephants have an exceptionally high number of facial neurons—perhaps the most known to any land-dwelling mammal—and scientists are theorizing why.

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2 years

Researchers have identified a single nucleotide substitution in a gene that causes reduced flower coloration in a self-pollinated monkeyflower species. Learn more in this week’s issue of Science Advances:

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8 months

New research out this week in Science Advances highlights the importance of conserving avian evolutionary history, and how it also benefits humans:

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11 months

To understand how the pancreatic tumor microenvironment contributes to disease progression, researchers have developed an experimental model allowing for direct, microscopic visualization of human pancreatic tumors. Learn more in this week’s issue:

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2 years

New studies in genetic mutations, the inner workings of the ocean food web, and more, in this week’s issue of Science Advances.

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5 months

New research provides combinatorial strategies to overcome immunotherapy resistance in tumors. Learn more in this week's issue of Science Advances:

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3 years

New research in fear learning, alcoholism, language families, and #COVID19 disease susceptibility. Check out this week’s Science Advances:

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1 year

Inspired by the human retina, researchers have created an #imaging sensor to detect all visible colors in the spectrum. The device could lead to more efficient and intelligent imaging methods.

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2 years

An update on the controversial DAMA collaboration, the effects of a high-sugar diet on the development of #schizophrenia and #BipolarDisorder , and more in this week’s Science Advances:

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3 years

Are U.S. conservatives less able to distinguish truth from falsehoods? A six-month study contains fascinating revelations. This story, and more, in the new Science Advances:

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2 years

Vampire bats are the only mammals that feed exclusively on blood—and scientists may have identified the gene losses responsible for this unique evolution.

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2 years

Programmable dressings that may help wounds heal faster, discovering meteorites using machine learning, and helping frogs regrow their hind legs—all new in this week’s Science Advances:

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22 days

New research finds in response to stressful conditions, nematode morphs develop an enlarged mouth and engage in cannibalism. Learn more in this week’s issue of Science Advances:

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3 months

To meet emerging demands of personalized medicine, #StemCells must be made at a large scale while maintaining high quality and low cost. New research in Science Advances shows an all-in-one sensor system that can continuously monitor stem cell cultures.

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1 year

Using electron microscopy and deep learning, researchers have unraveled the complex intercellular connections that bridge pairs of cerebellar granule cells throughout the external granular layer of the cerebellum. Learn more in this week’s issue:

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1 year

For flying insects like #Drosophila , maintaining aerial stability is a constant balancing act. Researchers have identified key roles for two prominent wing steering muscles that fruit flies use to actuate these reflexes. Read more in this week’s issue:

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11 months

This week in Science Advances, researchers investigate the effect of ocean alkalinity enhancement, a process that sequesters carbon by increasing ocean alkalinity through the addition of limestone and other alkaline minerals. Read that study and more:

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7 years

ICYMI: Scientists now understand what makes bioluminescent mushrooms #glowinthedark

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2 years

New research explores the assembly of complex 3D structures and electronics on curved surfaces. Learn more in this week’s issue of Science Advances:

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1 year

Nanorobotics researchers developed a glioblastoma (GBM) treatment using magnetic carbon nanotubes and precision magnetic field control, a potential alternative therapy for chemoresistant #GBM .

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10 months

Much of how spatial asymmetry organizes in cells and how cells form organs is still unknown. Two studies propose a mechanism that brings about the asymmetric organization of the cellular membrane from within the cell. Learn more in this week's issue:

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1 year

Researchers have developed a new stretchable wireless bioelectronic device that can be worn to monitor and heal chronic wounds.

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1 year

Eukaryotes that lack mitochondria may fall at the base of the eukaryote evolutionary tree, according to a new analysis.

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5 months

#QuantumKeyDistribution (QKD) can secure a global satellite network by combining high-clock rate QKD and #LaserCommunication technology. The process can transfer 5.2 Mbit of key in a single satellite pass.

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2 years

In the wild, octopuses use a combination of controllable adhesives and intricately embedded abilities to manipulate objects underwater. Scientists have now harnessed these abilities to create a wearable glove. Learn more in this week’s Science Advances:

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7 years

Genetic engineering turns chrysanthemums true blue @naonobu_noda

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3 years

An analysis of 14 populations encompassing 11 language families in northeast Asia finds a correlation between the grammatical structure of a population’s language and its genetic history.

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1 year

A new study in mice sheds light on the origin of taste. Learn more in this week's issue of Science Advances:

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3 years

An inhalable treatment that prevented and eliminated SARS-CoV-2 infections in hamsters, and how the salmon aquaculture industry may have spread a virus to wild salmon populations. These stories and more, in the new Science Advances:

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3 years

Newly designed origami-based materials that can become stiffer or more pliable on demand and a novel system for building mechanical metamaterials. Read what’s new in Science Advances:

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1 year

Researchers have generated a comprehensive profile to identify potential drug candidates to treat rhabdomyosarcoma, one of the most common types of pediatric cancers. Learn more in this week's issue:

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1 year

Researchers have designed an ultrasonic tweezer that can move a droplet through an opening narrower than its diameter, over a steep slope, and even up a vertical surface. Learn more in this week’s issue of Science Advances:

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1 year

A new model using news streams may be able to help predict food crises up to a year in advance.

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3 years

A new study based on data from farms and wastewater treatment plants in the United Kingdom finds that habitat and local geography may play a stronger role in the evolution of antimicrobial resistance than bacterial phylogeny or the season.

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