Thibaut Brunet @thibaut_brunet Twitter profile

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Thibaut Brunet

1 month

First preprint from the lab! 🥳 We serendipitously discovered an unconventional type of multicellular development for choanoflagellates: mixed clonal-aggregative multicellularity. A (long, sorry) 🧵 summarizing our main findings ⬇️

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Thibaut Brunet

@thibaut_brunet

3 years

I am thrilled to (finally!) officially announce I will be joining the @BCI department of the @institutpasteur in Paris to start my own lab early 2022. Watch this space and for more details and open positions!

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Thibaut Brunet

@thibaut_brunet

2 years

Beyond excited and very grateful to have received an @ERC_Research starting grant for our project EvoMorphoCell @institutpasteur . We will research the pre-metazoan origin of the mechanisms that control animal cell shape and multicellular morphogenesis.

European Research Council (ERC)

@ERC_Research

2 years

🎉ERC Starting Grant competition results are out! Over €619 million for the best ideas of young leading researchers - and the 1️⃣st set of grants awarded under 🇪🇺 @HorizonEU . Find out who, where and why 👉 #EUfunded #FrontierResearch #ERCStG

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Thibaut Brunet

@thibaut_brunet

2 years

I haven't followed closely the discourse on Twitter over the part few weeks, but I just want to say I'm sternly opposed to Elon Musk buying eLife.

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Thibaut Brunet

@thibaut_brunet

4 years

When is a choanoflagellate not a flagellate? When it's an amoeba. Check out our new preprint with @Choano_Lab in which we report a new, amoeboid cell phenotype in the closest living relatives of animals:

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Thibaut Brunet

@thibaut_brunet

5 years

Check out our new preprint on a newly discovered choanoflagellate species: Choanoeca flexa, that forms large contractile colonies that quickly and reversibly flip inside-out in response to light:

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Thibaut Brunet

@thibaut_brunet

7 months

Check out our new review @CurrentBiology on the evolution of animal cell contractility - both in the unicellular-to-multicellular transition, and in the early animal diversification

Cell contractility in early animal evolution

Thibaut Brunet discusses recent molecular and biophysical studies in model and non-model organisms that have increased our understanding of how contractility has shaped animal evolution.

www.cell.com

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Thibaut Brunet

@thibaut_brunet

4 years

I like how thoroughly @NCBI seems to have prepared for the possibility that people might want to Blast sequences to the human genome when drunk.

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Thibaut Brunet

@thibaut_brunet

3 years

📣 We are about to open a core-funded post-doctoral position to work on morphogenesis and behavior in choanoflagellates @institutpasteur . Official job announcement coming soon. Please RT and get in touch if you're interested!

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Thibaut Brunet

@thibaut_brunet

6 years

In the honor of ctenophore day (10/04), here are ctenophores as they are maybe more rarely seen: a small, colorful congregation of benthic ctenophores hanging out (literally) on an old fishing line (picture from @calacademy and @CoralReefFish )

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Thibaut Brunet

@thibaut_brunet

4 years

Am I the only one to be confused by baby Yoda's morphology? Compared to old Yoda, it does have proportionately larger eyes, but a seemingly tiny/flat brain case. This differs from the ontogenetic allometry in humans (and all mammals?), whose babies have larger and rounder heads.

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Thibaut Brunet

@thibaut_brunet

2 years

Happy to share our new preprint, in which we have characterized an ancient animal intercellular communication system - nitric oxide signaling - in choanoflagellates. A short 🧵

Nitric oxide signaling controls collective contractions in a colonial choanoflagellate

Although signaling by the gaseous molecule nitric oxide (NO) regulates key physiological processes in animals, including contractility[1][1], immunity[2][2],[3][3], development[4][4]-[7][5] and...

www.biorxiv.org

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Thibaut Brunet

@thibaut_brunet

1 year

Congratulations to Núria Ros i Rocher who just received an @MSCActions Marie Curie fellowship to study choanoflagellate multicellular development in our lab! 🥳 To the next 2 years of discoveries!

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Thibaut Brunet

@thibaut_brunet

2 years

Very happy to have received the Young Researcher Prize from the @SBCF1 , and especially honored to follow many great colleagues (including but not limited to @LevayerR , @maitrejl , @DariaBonazzi , @LeioValon , @GoetzJacky ).

SBCF

@SBCF1

2 years

@SBCF1 is more than happy to announce the 2022 Young Researcher Prize to Thibaut Brunet @institutpasteur ! Seminar on June 3rd @institutcochin during the General Assembly of the Society to learn more on "The origin of animal morphogenesis: insights from choanoflagellates"!

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Thibaut Brunet

@thibaut_brunet

2 months

Very touched and honored to receive a distinction from @EMBL , the place my scientific journey began. Huge thanks to my amazing mentors, colleagues and trainees over the years - it takes a village (in today's globalized world, even a planet) to do good science.

EMBL

@embl

2 months

Congratulations, Thibaut Brunet and Giulio Superti-Furga! The two EMBL alumni have received the 2024 John Kendrew Award and Lennart Philipson Award, respectively, for their outstanding work in the fields of evolutionary biology and molecular medicine.

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Thibaut Brunet

@thibaut_brunet

5 years

Our paper on a newly discovered choanoflagellate that forms contractile multicellular sheets is now published @sciencemagazine . So nice to see one of our beloved organisms on the cover! [insert a pun here about covers and sheets]

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Thibaut Brunet

@thibaut_brunet

1 year

Just got habilitated! thanks to the jury members @Patbio94 @PatrickLemaire_ @maitrejl Evelyn Houliston ( @Clytia_Vlfr ) @Azimzadeh_Lab and Laurent Théodore for having made this very French ritual into a painless and even pleasant scientific discussion 🎉

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Thibaut Brunet

@thibaut_brunet

3 years

Happy to see this published after a long pandemic revision: with a lot of new data motivated by constructive and thorough reviewer comments.

A flagellate-to-amoeboid switch in the closest living relatives of animals

The closest living relatives of animals, the choanoflagellates, switch from a flagellate to an amoeboid phenotype under confinement.

elifesciences.org

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Thibaut Brunet

@thibaut_brunet

2 years

Had a really fun time talking with @KatherineJWu for this piece that addresses how unfamiliar forms of multicellularity challenge our concepts of individuality, life and death

Something Strange Happens When You Tear These Creatures Apart

Behold choanoflagellates, tiny creatures that can be one body and many bodies all at once.

www.theatlantic.com

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Thibaut Brunet

@thibaut_brunet

6 months

Left: 8 months ago, I asked GPT4 to come up with memes in the style of @OdedRechavi . Right: cover of @Nature this week. Coincidence?

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Thibaut Brunet

@thibaut_brunet

2 years

And we're live: Come join us @BCI_Pasteur ! Center of Paris, great facilities, emerging model system, and long-standing evolutionary questions revisited in the light of modern cell biology.

Thibaut Brunet

@thibaut_brunet

3 years

📣 We are about to open a core-funded post-doctoral position to work on morphogenesis and behavior in choanoflagellates @institutpasteur . Official job announcement coming soon. Please RT and get in touch if you're interested!

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Thibaut Brunet

@thibaut_brunet

8 months

Grateful and excited to have been appointed as a 2023 Vallee scholar Support from @TheValleeFdn will allow us to develop a new direction in our research: understanding choanoflagellate multicellularity in its natural ecological context. Thanks!

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Thibaut Brunet

@thibaut_brunet

1 year

@OdedRechavi Here is what Bing comes up with (after having been asked to summarize your tweeting style).

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Thibaut Brunet

@thibaut_brunet

1 year

Happy to share the first study from our collaborators in Ray Goldstein's lab modelling the physics of inversion, swimming and feeding in multicellular choanos. A short 🧵

Swimming, Feeding and Inversion of Multicellular Choanoflagellate Sheets

The recent discovery of the striking sheet-like multicellular choanoflagellate species Choanoeca flexa that dynamically interconverts between two hemispherical forms of opposite orientation raises...

www.biorxiv.org

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Thibaut Brunet

@thibaut_brunet

3 years

Nice coverage of our study of amoeboid choanoflagellates and of its implications for cell type evolution in @NewsfromScience

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Thibaut Brunet

@thibaut_brunet

4 months

Very much looking forward to this event on Jan 29, where we'll gather the @institutpasteur evolutionary biology community with @CamLBerthelot @BIUPasteur @G_Frasca + special guest keynote by @eme_laura 🤩 DM me if you're a non-Pasteurian and would like to attend!

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Thibaut Brunet

@thibaut_brunet

1 month

PS: we are not planning to submit the story to a journal right away - instead, we see this as a "living" preprint that we'll update based on feedback from the community (and likely with a few extra data) before sending it out. Comments/suggestions/criticisms are all very welcome.

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Thibaut Brunet

@thibaut_brunet

2 years

📢 Annoucing our next @institutpasteur #QBio symposium on Dec 12-13, exploring the interface between mechanics, morphogenesis and evo-devo. Fully hybrid, registrations open for on-site and virtual attendees. Talks will be in the morning (US east time)/afternoon (Europe time).

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Thibaut Brunet

@thibaut_brunet

22 days

Decide to test commuting by train from Naples to Paris on the way back from #EMBOmarineImaging at @SznDohrn as a small step in cutting down on flying. Long (17 hours) but very smooth so far, with beautiful Alpine landscape as a bonus!

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Thibaut Brunet

@thibaut_brunet

4 years

What makes humans human? This new preprint by @BrainOrganoid et al, which compares brain organoid development in chimps, gorillas and humans, is really impressive and can't help but remind me of a very old theory of human brain evolution 🧵

An early cell shape transition drives evolutionary expansion of the human forebrain

The human brain has undergone rapid expansion since humans diverged from other great apes, but the mechanism of this human-specific enlargement is still unknown. Here, we use cerebral organoids...

www.biorxiv.org

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Thibaut Brunet

@thibaut_brunet

1 month

A long-awaited preprint! A "unicellular" animal relative that undergoes cleavage to give rise to a morula-like stage with different cell types, under the control of an endogenous developmental program - wow! I also love this because of its historical resonance (see below)

Omaya Dudin 𓂆 ¦🍉¦ 🇵🇸 ¦🦠¦🔬¦

@dudin_o

1 month

#PreprintAlert 🚨Please share. Our latest #Ichthyosporean #EvoDevo story, led by M. Olivetta @ChandniBhickta @NChiaruttini & in co. with @burnsajohn . **𝗧𝗵𝗶𝘀 𝗶𝘀 𝗡𝗢𝗧 𝗮𝗻 𝗮𝗻𝗶𝗺𝗮𝗹 #𝗲𝗺𝗯𝗿𝘆𝗼** LINK ➡️ Buckle up for a LONG 🧵(sorry)

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Thibaut Brunet

@thibaut_brunet

1 year

Check out our new review with @dsboothacosta on the pre-metazoan origin of cell polarity and cell polarization mechanisms

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Thibaut Brunet

@thibaut_brunet

3 years

@MereSophistry how to gain muscle [in only 600 million years]

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Thibaut Brunet

@thibaut_brunet

2 months

I expect every speaker at that conference will start by thanking the Organizer

Alfonso Martinez Arias

@AMartinezArias

2 months

First time in Freiburg, the edge of the Black Forest, courtesy of @realArnoldLab . Looking forward to be back for the centennial celebration of the Spemann-Mangold organizer in the City where it all happened. It promises to be a feast of #DevBio . Join in

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Thibaut Brunet

@thibaut_brunet

2 years

Excited that our our essay on the history of hypotheses of animal origins (preprint here ) is about to come out in print format! kudos to the editors for putting the book together

The Single-Celled Ancestors of Animals: A History of Hypotheses

Animals, with their complex and obligate multicellularity, evolved from microbial eukaryotes that were likely obligately or facultatively unicellular. The nature of the unicellular progenitors of...

www.preprints.org

Will Ratcliff

@wc_ratcliff

2 years

Chapter 13, by @thibaut_brunet and @A_Nicole_King , is titled “The single-celled ancestors of animals: a history of hypotheses.” This chapter provides a fascinating look back through the history of research on the unicellular ancestry of animals. 24/32

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Thibaut Brunet

@thibaut_brunet

4 years

There should really be a fellowship named "Jollygood". Recipients could say they are a "Jollygood fellow" and *nobody* could deny it.

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Thibaut Brunet

@thibaut_brunet

2 years

We still have a postdoc position open @BCI_Pasteur to work on one of our research directions about the origin of animal morphogenesis: multicellular development/behavior in C. flexa, collar morphogenesis, or amoeboid switch Please RT and spread the word!

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Thibaut Brunet

@thibaut_brunet

2 years

Really elated and proud that @A_Nicole_King , who propelled choanos onto the stage of modern cell and molecular biology, has been elected as a foreign member of @AcadSciences (now you have no excuse to not visit Paris!)

Académie des sciences

@AcadSciences

2 years

🌿16 nouveaux associés étrangers viennent d’être élus @AcadSciences . Parmi eux au titre de la section #Biologie #mol éculaire & #cellulaire , #g énomique 👉 Alberto R. KORNBLIHTT, prof. @Exactas_UBA @UBAonline Welcome to our new foreign associate members! ℹ️

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Thibaut Brunet

@thibaut_brunet

4 months

Worried about French politics lately. When I was a postdoc in the US under Trump, people used to post pictures of their lab with/without immigrants to highlight the vital contribution of immigration to science. So apropos of nothing, here's our lab with and without immigrants.

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Thibaut Brunet

@thibaut_brunet

4 years

. @JekelyLab just wrote up a thoughtful discussion of our study of a choanoflagellate displaying colletive contractility in @CurrentBiology - thanks Gaspar for raising many interesting points!

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Thibaut Brunet

@thibaut_brunet

3 months

Read "Life at low Reynolds numbers" for the first last week somehow and I am pretty amused that in Fig7, Purcell seems to have anticipated the morphology of Meteora sporadica in his speculations on the simplest conceivable microswimmer with just 2 degrees of freedom

Luis Javier Galindo

@Luisjagago

2 years

Happy to present our short manuscript on the re-description and molecular characterization of Meteora sporadica. Check our publication for new images and videos of this amazing organism 20 years after its original description. @DEEMteam_Orsay

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Thibaut Brunet

@thibaut_brunet

11 months

Some drama in today's live imaging: a choanoflagellate tries to phagocytose its neighbor, but has to give up because it's too big (fluorescence is actin - see that huge phagocytic cup!)

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Thibaut Brunet

@thibaut_brunet

4 months

Do sponges contract by relaxing? nice paper supporting a provocative but well-argued new hypothesis on the mechanism of sponge motricity (yes sponges do move)

Molecular profiling of sponge deflation reveals an ancient relaxant-inflammatory response

The evolution of coordinated behavior in early animals is largely obscure. Ruperti et al. uncover that sponge movement is driven by actomyosin stress fiber relaxation, regulated by Akt/NO/PKG/PKA....

www.cell.com

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Thibaut Brunet

@thibaut_brunet

2 years

Very happy to have arrived in #SunnyRoscoff for the Origin of Metazoans CNRS conference organized by ⁦ @Clytia_Vlfr ⁩ and ⁦ @ArnauSebe ⁩!

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Thibaut Brunet

@thibaut_brunet

2 years

Our study on nitric oxide signaling in choanoflagellates is now out @CurrentBiology ! With a few extra biochemical insights since the preprint

Nitric oxide signaling controls collective contractions in a colonial choanoflagellate

Although nitric oxide signaling regulates key physiological processes in animals, its premetazoan origin is unclear. Reyes-Rivera et al. report a full animal-like NO signaling pathway in a close...

www.cell.com

Thibaut Brunet

@thibaut_brunet

2 years

Happy to share our new preprint, in which we have characterized an ancient animal intercellular communication system - nitric oxide signaling - in choanoflagellates. A short 🧵

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Thibaut Brunet

@thibaut_brunet

3 years

Microtubules are underrated contributors to cell shape and shape changes. Nice new case study in apoptotic cell extrusion during Drosophila epithelial homeostasis

Levayerlab

@LevayerR

3 years

You may assume, like us, that every cell deformation is triggered by changes in actomyosin distribution/dynamics ? Then you may be surprised, like us, by what we found regarding cell extrusion and microtubules . Check this great work from @VillarsAlexis

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Thibaut Brunet

@thibaut_brunet

1 year

Very happy (and a bit emotional) to be back in ⁦ @UCBerkeley ⁩ for the 2023 Choanos & Friends meeting! Looking forward to catching up with fellow weird critter people (ie people interested in weird critters, not weird people interested in critters)

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Thibaut Brunet

@thibaut_brunet

3 months

Full house yesterday for the first Evolution & Biodiversity mini-symposium @institutpasteur . Heartwarming to see so much spontaneous enthusiasm for this topic across departments. Thanks to my awesome co-organizers, to the speakers/poster presenters and to the audience!

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Thibaut Brunet

@thibaut_brunet

5 months

. @EvaPillai has designed a great new logo for our lab. I guess we are all fused into one very large choanoflagellate rosette now

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Thibaut Brunet

@thibaut_brunet

1 year

Our review with Núria Ros-Rocher on choanoflagellate behavior just came out! give it a read for a summary of the (little) knowledge and (many) open questions on how choanos sense and respond to the world

What is it like to be a choanoflagellate? Sensation, processing and behavior in the closest...

Animal Cognition - All animals evolved from a single lineage of unicellular precursors more than 600 million years ago. Thus, the biological and genetic foundations for animal sensation, cognition...

link.springer.com

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Thibaut Brunet

@thibaut_brunet

1 year

We might have missed the kick-off in Roscoff, but we just received our first samples from the @EMBLtrec expedition 🤩 Looking forward to screening the waters of 🇪🇺 for choanos!

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Thibaut Brunet

@thibaut_brunet

2 years

Me doing a "quick bibliographic background search" for a review paper

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Thibaut Brunet

@thibaut_brunet

6 years

The "deep homology" mystery is getting deeper: like arthropod and vertebrate limbs, cephalopod arms/tentacles are patterned by similar molecules in similar arrangement, though they all evolved independently. Thought-provoking preprint by @CohnLab et al

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Thibaut Brunet

@thibaut_brunet

2 years

Excited to be giving on Thursday the first @VGZT2020_21 talk about organisms that don't actually gastrulate (but try their best)

Virtual Gastrulation Zoom Talks

@VGZT2020_21

2 years

The first and only rule of gastrulation club is : Everyone talks about the gastrulation club! To honor this rich tradition, we'll be joined by Dr Caroline Hill from @TheCrick and @thibaut_brunet from @institutpasteur . Join us this Thursday for a journey ranging diverse phyla!

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Thibaut Brunet

@thibaut_brunet

9 months

Saying goodbye to Curaçao after a stimulating week of fieldwork - a special and slightly strange feeling, to go back where it all started to better understand the natural life history of the choanos we’ve been studying in the lab for the past 5 years!

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Thibaut Brunet

@thibaut_brunet

1 year

Very happy to have visited for the first time ⁦ @Sars_Centre ⁩ in #sunnyBergen (where it was inexplicably raining, illustrating the difference between weather and climate I assume). So much cool, cutting-edge science there! Thanks ⁦ @Pawel_Burkhardt ⁩ for the invitation

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Thibaut Brunet

@thibaut_brunet

4 months

By popular demand, we just added a hybrid option to our Evolution & Biodiversity symposium (platform Microsoft Teams). Register here for the link:

Microsoft Forms

forms.office.com

Thibaut Brunet

@thibaut_brunet

4 months

Very much looking forward to this event on Jan 29, where we'll gather the @institutpasteur evolutionary biology community with @CamLBerthelot @BIUPasteur @G_Frasca + special guest keynote by @eme_laura 🤩 DM me if you're a non-Pasteurian and would like to attend!

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Thibaut Brunet

@thibaut_brunet

2 years

Happy to see this review out - a fun collaboration initiated by @AgChaigne on the role of incomplete/abscission cytoplasmic bridges in the evolution of eukaryotic multicellularity. A 🧵 with some personal highlights.

Dr Agathe Chaigne

@AgChaigne

2 years

Incredibly proud of this review on Incomplete abscission accross the tree of life; my first senior/independent work, co-authored with @thibaut_brunet out today in @CurrentBiology

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Thibaut Brunet

@thibaut_brunet

3 years

New preprint online, which represents our first foray into history of science! Feedback welcome. See summary thread below by @Choano_Lab :

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Thibaut Brunet

@thibaut_brunet

4 years

What is the state of the art in developmental mechanobiology? Where does it go next? Adrien Hallou ( @TLM_Cambridge ) and I report on last July's EMBL conference "Mechanical Forces in Development". Hope our short summary is as fun to read as it was to write!

Development

@Dev_journal

4 years

On growth and force: mechanical forces in development A Meeting Report from Adrien Hallou & @thibaut_brunet , who attended the @EMBO | @EMBL Symposium in September

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Thibaut Brunet

@thibaut_brunet

11 months

Happy to be back at @embl for the EMBL/EMBO conference on mechanobiology of the cell surface #EESCellSurface The view from the ATC hasn’t got any less stunning

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Thibaut Brunet

@thibaut_brunet

3 years

Imitation is the sincerest form of flatness

𝘔𝘪𝘬𝘬𝘰 𝘒𝘰𝘭𝘬𝘬𝘢𝘭𝘢

@XCsci

3 years

Did flatness evolve twice? #flatfishes #genomes #phylogeny Lü et al. 2021 (OA)

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Thibaut Brunet

@thibaut_brunet

1 year

Nothing in pastry makes sense except in the light of evolution

Rebecca Stevick

@rjstevick

1 year

I'm excited to share our ongoing work describing the dessert diversity at the canteen @institutpasteur ! 🧁 This study included extensive sampling of 102 independent samples over 3 years. Here's a 🧵 of our key findings. 1/7

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Thibaut Brunet

@thibaut_brunet

2 years

Looking forward to the @cdf1530 symposium on cell motility organized by @LecuitLab , starting tomorrow! with @robinsall @XavierTrepat @montell_denise @micromotility @PrakashLab @LennonLab @PierreSens @clhueschen @BLadoux and many others not on Twitter

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Thibaut Brunet

@thibaut_brunet

1 year

Kicking off the #memodevo symposium ⁦ @institutpasteur ⁩ with some great discussions on the interface of mechanics, development and evolution! (and even a little neuroscience)

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Thibaut Brunet

@thibaut_brunet

7 years

Check out our new review paper on animal origins ?amp=1

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Thibaut Brunet

@thibaut_brunet

8 months

Leaving #DevMeeting23 on unconventional model systems full of new ideas, great new acquaintances, and British culinary knowledge! Thanks to the organizers for an amazing time in beautiful and bucolic Wotton

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Thibaut Brunet

@thibaut_brunet

5 years

Don't say "large samples give more reliable average estimates" but "the N justify the means".

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Thibaut Brunet

@thibaut_brunet

9 months

Marine biology in Miami airport. Is this a ctenophore (right)?

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Thibaut Brunet

@thibaut_brunet

6 years

Our latest @NatureEcoEvo - Evolution of the bilaterian mouth and anus

Evolution of the bilaterian mouth and anus

Nature Ecology & Evolution - The bilaterian mouth and anus evolved from a simple gut with one gastric opening. Here, the authors review comparative data on several organisms and conclude that...

www.nature.com

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Thibaut Brunet

@thibaut_brunet

6 years

Choanoflagellates have existed for 800 million years, humans have been trying to transfect them for 15 years, and only now is it finally working: A transformative step for the choano community - congrats @dsboothacosta and @Choano_Lab !

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Thibaut Brunet

@thibaut_brunet

5 months

Looking forward to #cellbio2023 @ASCBiology starting tomorrow with 2 symposia close to my heart - Evolutionary Cell Biology in the morning, Cells in the Wild in the afternoon (where I’ll speak - thanks @guille_rochelle @BEuplotes @dsboothacosta for the opportunity)!

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Thibaut Brunet

@thibaut_brunet

5 months

Excellent update on the inside-out model of eukaryogenesis in the light of new data on Asgard archaea. I especially enjoyed the list of potential observations that would contradict the hypothesis at the end - we should all do this

Buzz Baum

@BaumBuzz

5 months

Ever wondered how eukaryotic cells got their nucleus? Check out this new hypothesis paper in which Anja Spang and I explain our idea - building on the inside-out model of eukaryogenesis:

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Thibaut Brunet

@thibaut_brunet

3 years

Glad to have enjoyed for the last time a perk of the Bay Area: a trip to local tide pools with @Choano_Lab members. Now let's see what those samples look like under a microscope!

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Thibaut Brunet

@thibaut_brunet

3 years

@Hoosierflyman 3 years is pretty short for a postdoc

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Thibaut Brunet

@thibaut_brunet

5 months

Always good to be back in the US.

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Thibaut Brunet

@thibaut_brunet

2 years

A lamp seen in a restaurant in Paris. @A_Nicole_King , remind you of anything?

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Thibaut Brunet

@thibaut_brunet

1 year

Fascinating new work showing that the ctenophore nerve net is a syncytium. This shows that fundamental discoveries in comparative anatomy in major animal groups are still possible- but also raises so many interesting evolutionary and neurobiological questions. Congrats!

Pawel Burkhardt

@Pawel_Burkhardt

1 year

Wonderful perspective by @caseywdunn in @ScienceMagazine about our recent paper. Neurons that connect without synapses. The ctenophore nerve net suggests a complex evolutionary history of the animal nervous system. Thank you!

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Thibaut Brunet

@thibaut_brunet

2 years

Finally got access to @OpenAI 's DallE2 (yay!). Here are a few AI-generated images I enjoyed (together with the prompt they were produced from). "A phylogenetic tree painted by René Magritte"

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Thibaut Brunet

@thibaut_brunet

6 years

The ping pong tree carnivorous sponge is, to my knowledge, the only animal strange enough to have been first mistaken for an alien artefact

Eltanin Antenna - Wikipedia

en.wikipedia.org

Stanford Center for Ocean Solutions

@oceansolutions

6 years

#DidYouKnow The ping pong tree sponge Chondrocladia lampadiglobus is a type of carnivorous sponge. It can capture and digest small crustaceans using its translucent spheres. #FridayOceanFact Image: @MBARI_News

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Thibaut Brunet

@thibaut_brunet

2 years

Asked DALL•E 2 from @OpenAI to draw "a lamp in the shape of Choanoeca flexa" and I'm mildly scared of the result. Uncanny how fast AI is progressing in certain areas

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Thibaut Brunet

@thibaut_brunet

3 months

Had a blast visiting @IGFLyon today - such excellent and diverse research in fundamental organismal biology here. Thanks @LeulierFrancois for the invitation!

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Thibaut Brunet

@thibaut_brunet

2 years

Two metazoan-like (probable) neuropeptides discovered in choanos! exciting to contemplate what they might be doing

Luis Yanez-Guerra

@LuisAlfonsoYan2

2 years

Did neuropeptides evolve before neurons? We have identified the first neuropeptide precursors in sponges and choanoflagellates, and they seem to be homologous to bilaterian precursors. Thanks to @JekelyLab for the full support and guidance to perform this

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Thibaut Brunet

@thibaut_brunet

2 years

What a massive and wonderful surprise: the very first @NobelPrize for evolutionary biology!

The Nobel Prize

@NobelPrize

2 years

BREAKING NEWS: The 2022 #NobelPrize in Physiology or Medicine has been awarded to Svante Pääbo “for his discoveries concerning the genomes of extinct hominins and human evolution.”

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Thibaut Brunet

@thibaut_brunet

1 year

Flowers for Metchnikoff ⁦ @institutpasteur ⁩

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Thibaut Brunet

@thibaut_brunet

4 years

@OdedRechavi "Leave the samples in the primary antibody overnight", or in other words:"dye another day"

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Thibaut Brunet

@thibaut_brunet

5 months

Immensely looking forward to #EED2024 in Helsinki, with symposia on a lot of my favorite topics - evolution of morphogenesis, developmental constraints, developmental system drift, eco-evo-devo, and of course evo of multicellularity/evo cell bio/protistology! Join us!

Euro Evo Devo 2024

@EED2024

5 months

We're thrilled to announce the selection of 24 exciting symposia for our upcoming Helsinki #EED2024 conference! 🧬🔬🐿️🐀🦜🐊🐠🦑🦟🪱🍀🦠 Happy holidays and see you all in Helsinki! More information here: Abstract submission details to follow in early 2024!

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Thibaut Brunet

@thibaut_brunet

4 years

Same for 'higher animals'. Darwin put it as well as anyone else: "It is absurd to talk of one animal being higher than another."

Ross Waller

@RossWaller3

4 years

'Higher eukaryotes', please stop using this term, it is so loaded with ill-defined assumptions. If you're describing complexity, do that, but with context because us animals are not always more complex. Higher eukaryotes are the ones on mountains. Some prokaryotes are even higher

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Thibaut Brunet

@thibaut_brunet

5 years

What an opus! A plethora of new sponge cell types, an ancient role for nitric oxide in sensory-contractile cells, and a possible evolutionary link between neurons and immune cells (and their respective synapses) - plus much, much more. Congrats Jake Musser, @wormduty et al!

Arendt Lab

@wormduty

5 years

We have just deposited onto Bioarxiv: "Profiling cellular diversity in sponges informs animal cell type and nervous system evolution".

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Thibaut Brunet

@thibaut_brunet

9 months

@LecuitLab local distorsion of the water surface by gerris legs acts as a diverging lens and causes a dark spot? pretty nice!

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Thibaut Brunet

@thibaut_brunet

3 years

Delighted to be preLighted!

preLights

@preLights

3 years

Tracing the history of animal origins By @HiralABShah @Dey_Gautam and @dudin_o on preprint from @thibaut_brunet @Choano_Lab with thoughtful author's comment!

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Thibaut Brunet

@thibaut_brunet

1 year

⁦ @bruvellu ⁩ from ⁦ @PavelTomancak ⁩ lab telling about the evolution of a mysterious structure: the Drosophila cephalic furrow #MeMoDevo

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Thibaut Brunet

@thibaut_brunet

16 days

"There is an urgent need for France to implement long-term science-informed policy-making." Clear-sighted and thoughtful analysis of the paradoxical relationship of our current government with science, by @PatrickLemaire_ and F. Massol @SocSavantes2

France needs a chief science adviser

France is at a crossroads, facing environmental and social challenges that are profoundly altering its society. Yet, the French government keeps prioritizing short-term political gains over long-term...

www.science.org

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Thibaut Brunet

@thibaut_brunet

2 years

Enjoying great discussions at the 'Cancer, Multicellularity, & Complex Systems' ⁦ @lunduniversity ⁩ symposium organized by ⁦ @hammarlund_emma ⁩! I'm especially enjoying the tasteful choice of choano-shaped lamps at the venue.

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Thibaut Brunet

@thibaut_brunet

5 months

Had a very fun day learning about the diverse and exciting science @IBDMmarseille . This felt too short - hoping to come back soon!

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Thibaut Brunet

@thibaut_brunet

2 months

Sunrise in @HHMIJanelia

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Thibaut Brunet

@thibaut_brunet

2 years

Thomas Cavalier-Smith's final - and posthumous 😢 - paper: a monumental 100-page monograph on the evolution of the ciliary transition zone. In typical TCS fashion, this is not *only* an encyclopedic synthesis, but is also full of bold, clever, and though-provoking hypotheses.

Jékely Lab @[email protected]

@JekelyLab

2 years

The last (sadly) masterly mega-paper from Tom Cavalier-Smith, on ciliary transition zone evolution. Published posthumously in Protoplasma. My appreciation in a thread. 1/25

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Thibaut Brunet

@thibaut_brunet

6 years

Animal Evolution: Convergent Nerve Cords? @CurrentBiology

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Thibaut Brunet

@thibaut_brunet

5 years

Ichthyosporeans have a cell layer that resembles an epithelium and forms by a Drosophila-like cellularization mechanism. Great to see such beautiful cell biology in unicellular relatives of animals!

Omaya Dudin 𓂆 ¦🍉¦ 🇵🇸 ¦🦠¦🔬¦

@dudin_o

5 years

Our new preprint is out! It describes an #epithelium -like layer of cells in a #unicellular relative of #animals . 𝗔. 𝗢𝗻𝗱𝗿𝗮𝗰𝗸𝗮, @xgraubove ,𝗔. 𝗛𝗮𝗿𝗮𝗹𝗱𝘀𝗲𝗻,𝗔. 𝗧𝗼𝘆𝗼𝗱𝗮, 𝗛. 𝗦𝘂𝗴𝗮, @___JonB___ , @multicellgenome #Evolution #Actin #Science

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Thibaut Brunet

@thibaut_brunet

3 years

@Caroline_Bartma or a Rudyard Kipling poem: "IF you can bind tightly, and yet be specific IF even excited you don't bleach too quickly IF you can be washed and hang in there, You'll be an image, my sample!"

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