Jay Hennig @jehosafet Twitter profile

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Jay Hennig

21 days

Big news, I just accepted an offer to join Baylor College of Medicine's Dept of Neuroscience as an asst professor! I start Fall 2024, and I'm looking for phd students, postdocs, and research scientists to join me studying learning in neural populations.

Hennig Lab

www.henniglab.org

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Jay Hennig

@jehosafet

3 years

I am so so excited to see this work published in @NatureNeuro ! "Learning is shaped by abrupt changes in neural engagement" pdf: (1/n)

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Jay Hennig

@jehosafet

3 years

"Some people give beautiful presentations but go down in flames during the chalk talk." 🤦 Maybe that's because no one is ever allowed to see a chalk talk until they're giving their own?

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Jay Hennig

@jehosafet

3 years

Just defended my phd--feeling pretty great!!

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Jay Hennig

@jehosafet

3 years

Excited to share we ( @yulikeneuro @aaronbatista and others) have a perspectives paper on learning in neural population activity out now! "How learning unfolds in the brain: toward an optimization view" 📎 (1/n)

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Jay Hennig

@jehosafet

4 years

Excited to share a preprint of our work "Learning is shaped by abrupt changes in neural engagement," advised by Aaron Batista, Steve Chase, and Byron Yu. I'm (even more?) excited to finally make my own #tweeprint ! (1/n)

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Jay Hennig

@jehosafet

1 year

Hi! I wanted to share a #tweeprint of the results in my first postdoc paper, "Emergence of belief-like representations through reinforcement learning", with my new friends @gershbrain @naoshigeuchida @Sandra_RoPi @scott_linderman (1/n)

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Jay Hennig

@jehosafet

4 years

Congrats to @BenjoCowley and team for getting this awesome paper out! They find that firing rates in V4 and PFC show a large, "slow drift" over time that correlates with animals' impulsivity. May you never treat your trials as independent samples again.

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Jay Hennig

@jehosafet

3 years

There's lots of neuro papers studying learning, but few that I can find where neural activity was analyzed throughout learning, as opposed to just before/after. Anyone have any favorites? (Bonus points if they don't average firing rates across neurons!)

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Jay Hennig

@jehosafet

2 years

"CS" and "US" in classical conditioning has to be the worst pair of acronyms ever agreed upon. It takes conscious attention for me to figure out which is which every...single...time

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Jay Hennig

@jehosafet

4 years

Which line do you think does a better job of predicting Y given X? (Hint: This is one of those days where very basic statistics confuses the hell out of me.) (1/n)

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Jay Hennig

@jehosafet

2 months

"Learning leaves a memory trace in motor cortex" Out today in Current Biology! Led by Darby Losey, with myself, Emily Oby, @MattGolub_Neuro , @aaronbatista , @YuLikeNeuro , Steve Chase, and team. 📎: 🧵:

Jay Hennig

@jehosafet

2 years

"Learning alters neural activity to simultaneously support memory and action" Excited to share a new preprint, led by Darby Losey, with myself, Emily Oby, Aaron Batista, Byron Yu, Steve Chase, and team. 🧵

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Jay Hennig

@jehosafet

2 years

"Learning alters neural activity to simultaneously support memory and action" Excited to share a new preprint, led by Darby Losey, with myself, Emily Oby, Aaron Batista, Byron Yu, Steve Chase, and team. 🧵

Learning alters neural activity to simultaneously support memory and action

How are we able to learn new behaviors without disrupting previously learned ones? To understand how the brain achieves this, we used a brain-computer interface (BCI) learning paradigm, which enables...

www.biorxiv.org

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Jay Hennig

@jehosafet

2 years

Take a population of neurons, and then sort them based on when their peak firing rates happen in time. - are there agreed on statistics for quantifying this temporal structure? - anyone know the ref for that paper about the importance of cross-validation when making these plots?

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Jay Hennig

@jehosafet

8 months

Our paper on probabilistic representations in RNNs during reinforcement learning is now up at @PLOSCompBiol ! The reviewers made some really great suggestions that I think improved the paper a lot since the preprint.

Emergence of belief-like representations through reinforcement learning

Author summary Natural environments are full of uncertainty. For example, just because my fridge had food in it yesterday does not mean it will have food today. Despite such uncertainty, animals can...

journals.plos.org

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Jay Hennig

@jehosafet

4 years

It's time for the 1st annual #tweeprint census! 🤓📊 Since June of this year, I've been collecting as many neuroscience and neuro-related tweeprints on @tweeprint as I could find. I just analyzed all 251 of them, and wanted to share what I found. (1/n)

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Jay Hennig

@jehosafet

3 years

Some fun life news I haven't shared yet: I've moved to the Boston area and will be starting a postdoc in August with @gershbrain ! Really excited to learn about dopamine/RL, but also to have a good reason to tell my friends/family why dopamine squirts aren't about pleasure

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Jay Hennig

@jehosafet

3 years

Since today is representational drift day, I just wanted to share my two cents, as this is something I've been thinking a lot about in terms of population activity. (1/n)

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Jay Hennig

@jehosafet

3 years

If you're registered for #cosyne2021 tomorrow, come find out how internal states influence learning in population activity! I'll be there for sessions 1a and 1b ( #1 -077)

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Jay Hennig

@jehosafet

3 years

The comp neuro equivalent of Bob Dylan ( @MaryamShanechi ), Rolling Stones ( @mjaztwit ), The Beatles ( @shenoystanford ), Led Zeppelin ( @GStanleyNeuro ), and Buddy Holly ( @shreyaneuroctrl ) all opening for a high school band (me). Come check it out! Tomorrow 11am-1pm EDT at #NER2021

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Jay Hennig

@jehosafet

4 years

My kids, last month: - learned to crawl and to stand - tasted many foods for the first time - learned to recognize words Me, last month: - sat in one place for hours at a time, every day - ate oatmeal for breakfast every morning b/c it's easier - forgot my wifi password

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Jay Hennig

@jehosafet

3 years

How do you control a dynamical system with no stable fixed points? Asking because this is what parenting two toddlers feels like

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Jay Hennig

@jehosafet

2 years

It's finally out! I'm thrilled and excited to share this tour-de-force work on [topic], led by the talented [first author]. This was truly a team effort, including the twitterless [oldest PI]. Check out the paper here [link], or see thread 🧵

Marco Hein @marcoyannic.bsky.social

@marcoyannic

2 years

Paper announcement bingo

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Jay Hennig

@jehosafet

3 years

@grassmannian If you want to evenly distribute N points on the surface of a sphere, you can only do this exactly if N = 4,6,8,12, or 20. I don't know why but this fact just disturbs the hell out of me.

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Jay Hennig

@jehosafet

6 years

Really excited that my first first-author paper is now out @eLife ! We looked at how the brain selects which neural activity patterns to generate when there are multiple (redundant) options for effective control.

Constraints on neural redundancy

The distribution of redundant neural activity is coupled with task-relevant activity, which may limit the extent to which redundancy can be exploited by the brain for computation.

elifesciences.org

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Jay Hennig

@jehosafet

3 years

I honestly thought it would never happen, but Byron Yu just got a twitter account: @YuLikeNeuro

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Jay Hennig

@jehosafet

3 years

Today I turn 33. The #'s 33, 34, and 35 are each semi-prime because they are the product of exactly 2 primes. Because it's the longest run of semi-primes I am likely to live through, as of today I am officially in my semi-prime. (Sorry, I'm a dad, I can make these jokes now.)

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Jay Hennig

@jehosafet

3 years

Uh-oh, they're onto us

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Jay Hennig

@jehosafet

5 years

Matlab users: If you're tired of manually installing things from File Exchange (download, unzip, add to path, forget it exists, repeat), try out Matlab Package Manager! Installing something can be as easy as: >> mpm install export_fig

GitHub - mobeets/mpm: Simple Matlab package management inspired by pip

Simple Matlab package management inspired by pip. Contribute to mobeets/mpm development by creating an account on GitHub.

github.com

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Jay Hennig

@jehosafet

3 years

#cosyne2021 word frequencies (to tide us over until @neuroecology does his thing)

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Jay Hennig

@jehosafet

3 years

I am very proud of my cgi donut. Learning Blender has seriously been the most fun I've had learning something in a long time!

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Jay Hennig

@jehosafet

2 years

Some of the best life advice I ever received was @johannesburge convincing me it was okay to take a break and get a job before starting grad school

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Jay Hennig

@jehosafet

3 years

Whenever I'm struggling with writing, it feels like I know what I want to write but the words just aren't there. But then, once I've figured it out, I realize it was immature/foggy ideas that were the problem, not the words. Anyone else have this experience?

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Jay Hennig

@jehosafet

2 years

Wordle fun facts and strategy pack (1/n)

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Jay Hennig

@jehosafet

2 years

I wish there was an alternative to twitter that was just tweeprints and nothing else

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Jay Hennig

@jehosafet

2 years

Traveling before kids: buy a plane ticket, sleep on a friend's couch Traveling after kids: buy multiple plane tickets, find an airbnb, rent a car, rent cribs, rent car seats, buy groceries, entertain tired children in a place that's missing most of their favorite toys

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Jay Hennig

@jehosafet

3 years

Here's one example from @DurstewitzLab , looking at abrupt changes in population activity in PFC while rats learned a new rule: "Abrupt Transitions between Prefrontal Neural Ensemble States Accompany Behavioral Transitions during Rule Learning"

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Jay Hennig

@jehosafet

3 years

My toddler's current best guess at how counting works (said with extreme confidence): "1, 2, 3, blue, 9, green, red..."

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Jay Hennig

@jehosafet

2 years

Come for the beautiful figures, stay for the new method that lets you deconvolve and reduce dimensionality of calcium signals simultaneously (CILDS)

Byron Yu

@YuLikeNeuro

2 years

We've posted a new paper on dimensionality reduction of calcium imaging recordings. This work was led by Tze Hui Koh, jointly with Steve Chase, Misha Ahrens, Will Bishop, and team.

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Jay Hennig

@jehosafet

4 years

A Monday morning non-reject of a paper is pretty much the best news I could have hoped for! Feeling GREAT :)

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Jay Hennig

@jehosafet

4 years

This is so cool! I'd always figured (naively) that a neuron's dendrite branching pattern was relatively random, but clearly not the case if there are neurons with basically a mirror opposite structure!

Wei-Chung Allen Lee @darbly.bsky.social

@darbly

4 years

We found that most motor neurons had unique and recognizable branching patterns. This let us find left-right pairs of motor neurons that likely control the same muscle in opposite legs. Identifiability of motor neurons is a key advantage to studying motor control in the fly. 6/n

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Jay Hennig

@jehosafet

4 years

TIL: Let's say you've got 100-d data (e.g., firing rates of 100 neurons), and you want to find a dimension along which the activity is maximally autocorrelated. Surprisingly, even if your data is pure noise (i.e., iid Gaussian), you can expect to find a dimension with ρ ≈ 0.4.

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Jay Hennig

@jehosafet

4 years

Shit--I'm supposed to believe in my own models?

Ash Jogalekar

@curiouswavefn

4 years

The bare truth of science: 1. Nobody believes a computational model except the person who built it. 2. Everybody believes an experimental measurement except the person who made it.

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Jay Hennig

@jehosafet

3 years

For making the data you wish you had! An illustrator script for generating points from a 2D Gaussian with a particular covariance ellipse.

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Jay Hennig

@jehosafet

2 years

I made a Wordle spin-off where you get different crossword clues as hints. Try it out and let me know what you think!

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Jay Hennig

@jehosafet

5 years

Found this book in a conference room and was very excited by how creepy it looked. But it turned out to be super interesting! Written by a Stanford sleep researcher in the 70s. Turns out the author a) coined the term "REM," b) identified/named the five stages of sleep, ...

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Jay Hennig

@jehosafet

5 years

I should start keeping a collection of all my poor pretty figures that will never see the light of day...

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Jay Hennig

@jehosafet

2 years

@gershbrain Wow, this "work the bork" thing is oddly consistent. (I asked for "realistic" rather that "intuitive.")

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Jay Hennig

@jehosafet

4 years

Starting to look for a postdoc position, and I'm realizing how little I understand about how the academic world works. Everything seems so strategic and yet totally up to chance. Anyone have any good tips/resources for how to pick where to do a postdoc?

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Jay Hennig

@jehosafet

21 days

This is my dream job, and I feel so lucky to have landed it. I'm also lucky to have had some incredible mentors/role models to get me here: @realAlexHuk @jpillowtime @YuLikeNeuro , Steve Chase, @aaronbatista , @gershbrain

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Jay Hennig

@jehosafet

2 years

My childcare in Boston costs more than I make as a postdoc.

Dr. Jennifer Rubin

@jenn_rubin

2 years

This is my daycare costs for 2 children in Seattle during the month of July. Please tell me how grad students and postdocs are able to afford childcare.

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Jay Hennig

@jehosafet

3 years

Reminds me of press about neuroprosthetics gushing about "controlling things with your brain." (Guess how you control your arms?)

Sam Gershman

@gershbrain

3 years

As opposed to what?? Popular books and articles about the brain often promulgate a form of Cartesian dualism, making it sound surprising that mental events are produced by brain events.

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Jay Hennig

@jehosafet

3 years

Very excited to report that my toddlers are clearly Bayesians 🧐 When I ask them "what color is this?", they always guess "red" first, then "blue," then "green", apparently because those are the most likely answers based on my past questions.

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Jay Hennig

@jehosafet

3 years

It's so ridiculous how awful/non-existent retirement options are as a grad student and postdoc. Our pay is low enough, can't we at least get some decent retirement options?

Anne Urai - @neuromatch.social/@anneurai

@AnneEUrai

3 years

So grateful that in my 2.5 years as a postdoctoral fellow, my employer invested in my retirement plan. Receiving this gives me a real sense of financial security for the future! 🤔

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Jay Hennig

@jehosafet

7 years

@karpathy Proof by intimidation

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Jay Hennig

@jehosafet

5 years

@bcaessens @stevenstrogatz Let a=“xy”, where “x” and “y” are the first and second digit of a. And b=“wz”. Now add these like you learned in elementary school, where you add the ones column and then the tens In the ones col we know y+z=10, so we carry the 1. This means w+x+1=10 in the tens. Thus x+y+w+z=19

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Jay Hennig

@jehosafet

4 years

Finally, if you're interested, the (slightly incomplete) list of tweeprints I've collected is here: Also, please let me know if I have missed your tweeprint! (n/n)

Tweeprints

Tweeprints ID,Created at,# Likes,# RTs,User,User # followers,Likes/Followers,Url,Text 1323784660313321475,2020-11-04 0:30:32,0,1,Hassan_416,37,0,https://t.co/cY1qHsKdvr,This @tweeprint will look at...

docs.google.com

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Jay Hennig

@jehosafet

3 years

Anyway, just wanted to share my thoughts--I think neural drift is a super interesting feature of population activity, and one that has the potential to answer lots of really interesting questions about the brain. (n/n)

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Jay Hennig

@jehosafet

4 years

Just had our kids tested for lead in their blood, and one initially tested above the 5 mcg/dl threshold. Pittsburgh is a hotspot for this sort of thing. Below, the % of kids who tested above 5 mcg/dl. National average is "less than 5%". Thread on why this is fucked (1/n)

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Jay Hennig

@jehosafet

4 years

For anyone looking for a good way to play (board) games with friends online, here are a few tips (and please share your own!) (1/n)

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Jay Hennig

@jehosafet

2 years

3yo woke up sick, refused to eat/drink anything all day until about 4pm. At that point we thought, ER here we come. I tried one last thing: "Did you know every time you drink water it makes mommy make a funny noise?" He then drank all his water, and is apparently totally fine

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Jay Hennig

@jehosafet

4 years

Paper submitted! Only an immediate desk reject could bring me down now :)

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Jay Hennig

@jehosafet

5 years

Super excited to see this work published! Congrats to Emily for finishing such an awesome project. These were super difficult experiments for her to run, and a really challenging problem to think through! @MattGolub_Neuro @AlanDegenhart

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Jay Hennig

@jehosafet

4 years

The top 3 most-liked tweeprints from 2019: 1. Weight Agnostic NNs @hardmaru 2. High precision coding in mouse V1 @computingnature 3. Cortical Neuron as a Deep Artificial Neural Net @DavidBeniaguev (7/n)

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Jay Hennig

@jehosafet

5 years

Gotta love it when your advisors get caught in the act of offering conflicting advice 😆

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Jay Hennig

@jehosafet

3 years

I convinced them that if they wanted to go see the zebras they had to hold hands first

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Jay Hennig

@jehosafet

3 years

uhhhh what

Eiko Fried

@EikoFried

3 years

If you use MacOS, keep in mind that you can do this clicking the 'alt' button in nearly every software (preparing my syllabus right now).

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Jay Hennig

@jehosafet

2 years

@jmourabarbosa Another paper that belongs in this mix is this one by @niru_m @MattGolub_Neuro @ItsNeuronal @SussilloDavid @SuryaGanguli It's about RNNs but still very relevant in terms of cautioning against interpreting similarity using CCA/RSA

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Jay Hennig

@jehosafet

5 years

One thing that surprised me about having kids is how time gets recalibrated. A year used to feel like no time at all to me, but now I think about how much my kids will change in a year and it blows my mind!

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Jay Hennig

@jehosafet

5 years

Repeated addition is called multiplication, repeated multiplication is called exponentiation, and repeated exponentiation is called...tetration! And visualizing it gets you this pretty picture. (Found via @johncarlosbaez , my new favorite twitter account)

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Jay Hennig

@jehosafet

3 years

1) The inflexibility of neural variability throughout learning. 2) The brain's use of multiple learning processes, even for simple tasks. 3) Changes in neural activity that occur without regard to the task at hand, like changes due to synaptic turnover or internal state. (5/n)

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Jay Hennig

@jehosafet

3 years

The way my kid pronounces "spooky" is indistinguishable from the way he says "poopy." It's going to be a fun month.

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Jay Hennig

@jehosafet

6 years

The ML for Creativity and Design workshop at #NIPS2017 was my favorite part of the conference. So many great projects and discussions!

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Jay Hennig

@jehosafet

4 years

Tfw when your advisor says "this paper's getting really close" and then sends you 139 comments on the Methods section

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Jay Hennig

@jehosafet

5 years

At first I was skeptical of the idea of studying dexterity in rodents. But this video! My four-month-olds still can't do what this mouse is doing! (From a great talk today by @AdamHantman on the neural circuits of dexterity--including some awesome work by @bsauerbrei1 )

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Jay Hennig

@jehosafet

4 years

If the brain does gradient descent to learn, how does it backpropagate error through layers it doesn't have access to?

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Jay Hennig

@jehosafet

3 years

1. Work by @XuLunaSun finds gradual drift in motor cortical population activity during learning, and they see drift even for targets that *didn't* need to be learned. In this case, neural drift may be a way of "indexing" different motor memories (5/n)

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Jay Hennig

@jehosafet

3 years

You know you're doing a thorough lit review when google scholar rate limits you for (manually!) downloading too many bib files

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Jay Hennig

@jehosafet

21 days

Also a huge thanks to @lucylai_ , @JeffMYau , and @NeuroPolarbear for making this job happen and giving me so much advice on my application and job/chalk talks! I can't wait to talk science!

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Jay Hennig

@jehosafet

2 years

I can't think of a headline that's made me simultaneously this sad and angry

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Jay Hennig

@jehosafet

2 years

The end of Amy's Science paper made such an intriguing proposal: Maybe animal's choices are aligned w/ noise variability dimensions b/c they're using a decoder that's "general" rather than specific to the cues used in the task. So excited to see this fleshed out in a full paper!

Marlene Cohen

@marlenecohen

2 years

New paper! A very fun collaboration between @amymni and @cc_huang11 (with @BrentDoiron and me along for the ride) was just published in @eLife “A general decoding strategy explains the relationship between behavior and correlated variability” 🧵1/9

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Jay Hennig

@jehosafet

4 years

@neuroecology The funniest part of this is how at the end of explaining general intelligence and genetics and everything else, the last sentence says something like “the problem that remains is understanding photosynthesis”.

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Jay Hennig

@jehosafet

3 years

2. Our work in BCI learning also finds drift in motor cortical pop. activity during learning, and here it persists even when it *hurts* performance. In this case, drift is *not* learning--it looks more like the animal's arousal/engagement. (6/n)

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Jay Hennig

@jehosafet

2 years

I tried getting GPT-3 to write my research statement for me, and it failed miserably. Now what am I supposed to do...

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Jay Hennig

@jehosafet

5 years

Before our babies were born, Jess and I spent two yrs making music together. We put in a lot of time on these, so I’m really excited to finally share them! You can listen in full at . Let us know what you think! The video is some creepy/sloppy StyleGAN.

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Jay Hennig

@jehosafet

3 years

Overall, we suggest that to explain changes in neural activity during learning in terms of optimization, we should consider how ANNs and brains differ. We hope this will lead to better models of how neural activity changes during learning, and possibly better AI as well. (n/n)

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Jay Hennig

@jehosafet

5 years

Turns out being a good parent requires memorizing exactly which floorboards do not creak

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Jay Hennig

@jehosafet

5 years

My mom works full-time as a mime. When I told her I wanted to be a mime too, she was speechless.

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Jay Hennig

@jehosafet

6 years

Great write-up on my recent @eLife paper on neural redundancy. Their interpretation is that our results are consistent with M1 being controlled (e.g., by Pmd) subject to a minimal energy constraint. Very interesting to think about M1 as the plant and not as the controller!

Trends in Cognitive Sciences

@TrendsCognSci

6 years

Ta-Chu Kao and Guillaume Hennequin discuss recent work by Steven Chase and colleagues in a new Spotlight article "Null Ain’t Dull: New Perspectives on Motor Cortex"

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Jay Hennig

@jehosafet

3 years

In particular, using a BCI lets us make precise statements about how neural activity *should* change according to optimization. And yet, changes in neural activity during BCI learning are often not at all what you would expect of an ANN trained to learn the same task. (7/n)

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Jay Hennig

@jehosafet

3 years

Just found the loveliest tumblr

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Jay Hennig

@jehosafet

4 years

@JonAMichaels Same. Part of me thinks I should be working in the evenings, but by that point I'm so drained it just seems unhealthy

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Jay Hennig

@jehosafet

3 years

Super interesting result and idea! Representational drift in visual cortex for some types of information (natural images) but not others (gratings)

Michael Goard

@GoardMichael

3 years

Two new papers from the lab on representational drift in visual cortex in @NatureComms today! Thread below:

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Jay Hennig

@jehosafet

4 years

Is it just me, or is clicking "submit" on a manuscript one of the most nerve-racking parts about being a scientist

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Jay Hennig

@jehosafet

5 years

What visual neuroscientists should I be following? Is it just who I'm following or is the motor community way more active on twitter? @jcbyts @memming @jpillowtime any suggestions?

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Jay Hennig

@jehosafet

4 years

Where are most tweeprinted papers published? 136 of 251 tweeprinted papers were on a preprint server (93 on biorxiv). What really surprised me here though was how many tweeprinted papers were published in higher-impact journals such as nature/cell/elife... (3/n)

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Jay Hennig

@jehosafet

5 years

Me after giving my first guest lecture

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Jay Hennig

@jehosafet

4 years

Omg stop no more jokes please

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Jay Hennig

@jehosafet

3 years

Me, at Fedex: Hi, I'd like to mail this document. Fedex guy: Sir...We do not "mail", we SHIP. Me: Okay, I'd like to...ship this document? Him: Sure, I can help you with that.

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Jay Hennig

@jehosafet

4 years

Here's how neural activity varied trial-to-trial for each of 8 targets (each dot is a trial, color indicates target), before monkeys started learning a new BCI mapping. The orange lines summarize this variability. We're calling them "neural engagement axes." (6/n)

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