david friedberg @friedberg Twitter profile

Last Seen Profiles

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david friedberg

@friedberg

4 months

milei’s speech should be the media event of the year. every high school class in the US should break and watch it, then spend a week understanding the historical context behind his devastating truths. if you haven’t watched, please do. and share widely.

Aaron Slodov

@aphysicist

4 months

Milei's 2024 Davos talk, directly translated to English by AI (by heygen), in his own accent. Better than the dubbed version imo.

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david friedberg

@friedberg

5 months

last week i took on a new role as ceo @ohalo , a company we founded 4 years ago and have operated in stealth. @ohalo uses gene editing to completely reimagine agriculture, creating new plant varieties in major crops that were not previously feasible, significantly increasing…

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david friedberg

@friedberg

1 year

tomorrow's @theallinpod is done before it's recorded... cc @Jason @DavidSacks @chamath @sama

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david friedberg

@friedberg

3 years

north america is in the midst of a worsening mega drought, increasing the probability that any of a number of events could lead to a black swan-like economic/social crisis... (1/n)

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david friedberg

@friedberg

7 months

@Jason did they find your head?

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david friedberg

@friedberg

2 years

humans don't deserve nuclear power

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david friedberg

@friedberg

4 years

amazing paper. 40-60% of population that have NOT had SARS-CoV-2 already have activated T Cells to the virus! likely due to cross-reactivity w/ other "common cold coronaviruses". may explain large % having easy time clearing virus and/or mild/no symptoms.

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david friedberg

@friedberg

3 years

The Pandemic War is an actual war we must fight and win. the virus is surging, and evolving. we must surge back, and evolve faster than the virus. here's my proposed plan and analysis...

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david friedberg

@friedberg

1 year

@Jason you should stop tweeting about an event you are not running

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david friedberg

@friedberg

1 year

which was your favorite once-in-a-generation/decade crisis - the one of 2020, 2021, 2022, or 2023?

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david friedberg

@friedberg

1 year

"cash is now a risk asset" is a pretty big paradigm shift

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david friedberg

@friedberg

2 years

the greatest source of value & wealth creation in the 22nd century could be driven by terrestrial nucleosynthesis...

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david friedberg

@friedberg

3 years

incredible

Humanoid History

@HumanoidHistory

3 years

Jeff Bezos, June 2000: “If I could do anything, I would like to go help explore space.”

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david friedberg

@friedberg

1 year

i think what some predictors have wrong about generative AI is the expectation that it will create content in its current one-to-many form - one movie, one piece of music, a book, consumed by many...

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david friedberg

@friedberg

3 years

everything is going to decentralize. this battle isn’t going away... the rate of conflict between distributed and centralized control is escalating.

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david friedberg

@friedberg

3 years

4 years after starting The Production Board, today i’m happy to share details about some of our founded businesses and that we just closed on a new $300M investment. this is important work & will be my sole focus going fwd. exciting day! we’re hiring!

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david friedberg

@friedberg

2 years

maybe i can get that verified emoji now cc @elonmusk (+ @jason )

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david friedberg

@friedberg

3 years

everything is possible. persevere.

Hayley Arceneaux

@ArceneauxHayley

3 years

Even through my battle with cancer, I smiled, persevered, and when I was cured at @StJude , I felt like I was on top of the world. 💛 19 years later, still smiling, I became an astronaut with @inspiration4x and quite literally made it to the top of the world 👩‍🚀🚀🌎

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david friedberg

@friedberg

3 years

BTC has likely created more millionaires (10,000+?) and deca millionaires (1,000+?) than any company or startup in history. these are individual “retail” investors realizing these returns, not institutions, which may drive the Rise of Retail...

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david friedberg

@friedberg

3 years

absolutely incredible system designed by chinese research team converts co2 into starch with a series of chemicals + designer proteins(enzymes). 100g of catalyst convert 5g of co2 per hour into starch. nearly 10x more efficient than corn plants. food security. carbon uptake. etc.

Science Magazine

@ScienceMagazine

3 years

From carbon dioxide to starch—no plants required: Researchers have developed a novel, cell-free method of synthesizing starch from CO2 and hydrogen using a combination of chemical catalysts and a carefully selected set of enzymes in a cell-free approach.

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david friedberg

@friedberg

1 year

i just can’t stop AI’ing…

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david friedberg

@friedberg

4 years

the whole world experience has become like a bad episode of black mirror

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david friedberg

@friedberg

3 years

just fyi.. ucsf, uc berkeley and stanford are not leaving the bay area

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david friedberg

@friedberg

2 years

if, after all our bickering and disagreements, we can make it to episode 100, i have faith the world will make it too! congrats on ep100 besties @chamath @DavidSacks @Jason

The All-In Podcast

@theallinpod

2 years

we made it episode 100 -- reflecting on the first 100 shows -- answering fan questions -- nuclear threat -- markets -- $AMZN cost-cutting 🔊: 📺:

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david friedberg

@friedberg

3 years

it is simple: vaccinate 1% of the population per day and the pandemic is OVER by March. we have the doses. volunteers are on standby. we have parking lots to administer. drop the red tape. not via trad'l healthcare providers. states administer w volunteers in pkg lots. fin.

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david friedberg

@friedberg

1 year

has anyone seen a good reason besides "politics won't allow it" why we shouldn't have a Balanced Budget Amendment to the Constitution of the US?

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david friedberg

@friedberg

1 year

that got dark fast...

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david friedberg

@friedberg

1 year

not sure how much more of a red alert is needed about a looming Federal debt problem in the US. this estimate is from the US Treasury Dept

Lyn Alden

@LynAldenContact

1 year

The U.S. Treasury Department actually published this.

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david friedberg

@friedberg

3 years

we’re getting out there with this message. drop the red tape. let anyone get the vaccine. let any trained volunteer give it. take delivery out of the hands of healthcare system and make it a 24/7 wartime effort. good & fast > perfect & slow

Luz Peña

@LuzPenaABC7

3 years

#Covid | @GavinNewsom check out the vaccine distribution plan Tech CEO David @friedberg is proposing. “30 volunteers at each HS parking lot & give the💉 to 10,000 people a day. We can vaccinate the entire country in 30-45 days” Story:⬇️ @abc7newsbayarea

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david friedberg

@friedberg

3 years

the whole world has become a video game

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david friedberg

@friedberg

2 years

what defines a "journalist" today? does a person repeating what someone else said, without taking steps to verify their statement, qualify? ...

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david friedberg

@friedberg

3 years

this is a rosetta stone moment for biology. deepmind has translated the human genetic code into the physical machines (proteins) that run our body. 100s of new therapeutics will emerge as scientists map how molecules may interact with proteins to alter human health

Sundar Pichai

@sundarpichai

3 years

The AlphaFold database shows the potential for AI to profoundly accelerate scientific progress, greatly expanding our accumulated knowledge of protein structures and the human proteome overnight.

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david friedberg

@friedberg

1 year

seems almost inevitable coming out of all this that we will lower rates, higher inflation, for a significantly longer time, than anyone anticipated just 96 hours ago

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david friedberg

@friedberg

9 months

i had the thrill and honor to chat with astronaut (and fellow Cal alum) @Astro_Woody , from the @Space_Station yesterday. really fun convo on a wide range of topics. full video..

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david friedberg

@friedberg

2 years

i'm free tonight. so @DavidSacks and i will be doing AMA on @getcallin at 7PT tonight.. woke mobs, nuclear war, and lots of other things we know very little about will be discussed...

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david friedberg

@friedberg

2 years

2022 will see many announcements on the tremendous progress in age reversal using partial reprogramming of cells ... # of companies, capital invested, papers getting published all growing. stopping and reversing aging will not seem like fiction in a few years time..

Antonio Regalado

@antonioregalado

2 years

Altos Labs came out of stealth today with $3 billion in funding. Mission: unravel deep biology of cellular rejuvenation programming Funders: They don't disclose ((only ARCH)) Full list of the scientists that joined is here.

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david friedberg

@friedberg

2 years

this is Daisy, our recently-adopted puppy. she's one of #4000beagles rescued from an animal testing breeding facility run by inotiv ($NOTV). the DoJ identified extensive abuse and shut the facility down. many pups still need homes; if you'd like to adopt:

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david friedberg

@friedberg

2 years

@Jason @chamath @DavidSacks pass

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david friedberg

@friedberg

3 years

if enough people believe in something, it will become manifest. regardless of institutional forces against that belief.

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david friedberg

@friedberg

1 year

@Jason you should name it TWISTed because All In is a registered trademark associated with a non-profit podcast... good luck with your event!

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david friedberg

@friedberg

3 years

marin county doing it right. 5mins. drive in/walk up vax site. no insurance card needed. run by county, not hospital. setup in gym. can handle 2,000/day, roughly 1% of county population. they’ll be done by march at this rate! state of CA + other counties should replicate

ABC7 News

@abc7newsbayarea

3 years

Marin County may have the perfect strategy for running a smooth-operating mass vaccine distribution site.

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david friedberg

@friedberg

2 years

we will miss you

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david friedberg

@friedberg

10 months

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david friedberg

@friedberg

10 months

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david friedberg

@friedberg

2 years

feels like contagion territory. taking so much capital out of the global capital network, and turning off so many nodes on that network, so fast.. non-zero chance of feedback loops and cascades we don’t see yet.

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david friedberg

@friedberg

4 years

i dont think this paper is getting enough airtime. theorizes how and why coronavirus reduces blood O2 and causes "crushed glass" lung imagery (kicks out heme from RBCs), risk factors (high A1C, blood sugar, hemoglobin), and why certain treatments work

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david friedberg

@friedberg

3 years

mutant strain in SA strongly resistant to past immunity. ~8x reduction in neutralization (which is threshold used for updating flu vaccine). almost a new virus. existing covid vaccines powerful but likely getting less so. need to rapidly scale vax to keep new strain at bay.

Trevor Bedford

@trvrb

3 years

Important new study by Wibmer et al () of neutralization by convalescent sera on wildtype vs 501Y.V2 variant viruses circulating in South Africa. It shows that mutations present in 501Y.V2 result in reduced neutralization capacity. 1/10

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david friedberg

@friedberg

3 years

if you get a vaccine in CA, you need an ID, insurance card, and need to fill out a 1-pager. please, just drop the requirements, remove the care provider's liability for not collecting this info, and GIVE THE VACCINE!

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david friedberg

@friedberg

3 years

if you don’t think inflation is already here you missed what happened to the stock market.. companies aren’t performing better, we are just inflating everything; financial assets first. everything else will follow.

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david friedberg

@friedberg

3 years

1% A DAY MAKES THE PANDEMIC GO AWAY!

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david friedberg

@friedberg

3 years

“experts” have incentives too

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david friedberg

@friedberg

2 years

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david friedberg

@friedberg

4 years

what if 2020 is our least crazy year going forward?

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david friedberg

@friedberg

4 years

i’ve bought serological IgG/M test kits from US/China. not FDA approved, or being used, for diagnostics. distributing to random volunteers around SF Bay to self-administer/report. trying to find rate of positive asymptomatic carriers in gen pop. will publish data in real-time..

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david friedberg

@friedberg

9 months

that deafeningly loud crunch sound

The Kobeissi Letter

@KobeissiLetter

9 months

The U.S. Now Has: 1. Record $17.1 trillion in household debt 2. Record $12.0 trillion in mortgages 3. Record $1.6 trillion in auto loans 4. Record $1.6 trillion in student loans 5. Record $1.0 trillion in credit card debt Total mortgage debt is now more than double the 2006…

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david friedberg

@friedberg

1 year

everyone will enjoy their own personalized movie, music, book, news article, video game experience. it may seem silly one day that many humans listened to the same piece of music, watched the same movie, read the same book...

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david friedberg

@friedberg

3 years

$INAQ thrilled to have the legend @ryangraves join us at @Metromile as our newest board member, investing $50M in the business alongside @chamath @mcuban and others. thx @sacca for bringing us together!

Former Uber exec Ryan Graves just invested $50 million in an auto-insurance startup backed by Mark...

The $250 billion a year auto-insurance industry is dominated by players like Allstate and Geico. Graves is betting on Metromile.

www.businessinsider.com

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david friedberg

@friedberg

3 years

just do this non-stop. don’t wait for freezers to break.

NBC News

@NBCNews

3 years

Freezer storing vaccines breaks Thursday night in Seattle. Medical center posts urgent message, sets up 11 p.m.-2 a.m. appointments before doses expire. Hundreds show up in pajamas and robes to receive vaccine. All doses administered. - @KING5Seattle

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david friedberg

@friedberg

2 years

this is so important and true. breaking up “Big Tech” just for being “too big” may be popular but will almost certainly be inflationary if it reduces economies of scale… short-sighted populist policy that doesn’t solve any real problems…

Lawrence H. Summers

@LHSummers

2 years

I am very concerned that we may headed into a new era of Brandeisian populist antitrust policy that will make the US economy more inflationary and less resilient.

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david friedberg

@friedberg

3 years

insane this is just free and available. an age of extraordinary discovery is underway

Nature Portfolio

@NaturePortfolio

3 years

. @Nature has published the latest iteration of AlphaFold, a computational approach employing machine learning for predicting full-chain protein structure with high accuracy.

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david friedberg

@friedberg

1 year

amazing what he put together on his home computer. didn’t know how to code 4 years ago..

Mckay Wrigley

@mckaywrigley

1 year

I gave GPT-4 eyes. Here’s what I did: - added some data to a vision model - gave the AI camera access - asked it questions about the scene - it identified objects - it searched web for info - used that info to accurately answer Watch it get 3 questions 100% correct!

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david friedberg

@friedberg

1 year

everything feels irrational today

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david friedberg

@friedberg

2 years

unfortunately most consumers squandered their stimmies on short-term consumables and bad investments. now inflation and declining personal balance sheets are going to squeeze the biggest source of demand in US economy. sustained recession risk ahead

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david friedberg

@friedberg

2 years

accurately and instantly measuring the chemistry of the soil will change the sustainability and profitability equation for the 2B acres of farmland on Earth. tpb is thrilled to lead, with Founders Fund, an investment in breakthrough technology business Stenon..

Dominic

@_DominicRoth

2 years

Excited to announce our Series A to continue to help growers make profitable and sustainable cultivation decisions Led by Founders Fund ( @zebulgar ) & TPB ( @friedberg ) Stenon is making soil data available in seconds with the help of sensor-fusion and ML!

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david friedberg

@friedberg

2 years

strong trend line thusfar

david friedberg

@friedberg

4 years

what if 2020 is our least crazy year going forward?

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david friedberg

@friedberg

1 year

maybe we can just forgive it all

The Kobeissi Letter

@KobeissiLetter

1 year

The U.S. Now Has: 1. Record $16.5 trillion in household debt 2. Record $11.9 trillion in mortgages 3. Record $1.6 trillion in auto loans 4. Record $986 billion in credit card debt Total mortgage debt is now more than double the 2006 peak. Meanwhile, 36% of Americans have…

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david friedberg

@friedberg

4 years

as of today, 5 NBA teams have had a coronavirus RT-PCR test done on their players and 7 players are positive (a 9.3% positive result)

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david friedberg

@friedberg

2 years

the problem with the constitution DAO is that the maximum possible bid is completely transparent. the seller will just bid against the DAO to get their max bid. it’s past winning, now the more you raise the more expensive it gets..?!

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david friedberg

@friedberg

8 months

must watch from @allinsummit

The All-In Podcast

@theallinpod

8 months

All-In Summit: 2,851 Miles with @bgurley "The best talk in the history of All-In... and we need to get it out there immediately so it can start going viral." - David Sacks, @allinsummit 📷

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david friedberg

@friedberg

1 year

it seems more likely that AI won't replace the creator in the traditional model but rather will become the personalized content creator for each individual...

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david friedberg

@friedberg

1 year

expectant noise about the controversies of copyright material being used as training data in generative AI and how such systems aren't actually "creative". i just keep coming back to this video by UK "mentalist" derren brown..

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david friedberg

@friedberg

1 year

the big winners of tomorrow will likely be the minecraft youtubers of today

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david friedberg

@friedberg

3 years

we've normalized popups on the web again. now, it seems, your site isn't conversion-oriented enough without a popup! brutal that this is the evolution of all web UX. (and wishing i could re-install old school popup blockers)

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david friedberg

@friedberg

3 years

the US is administering ~250k covid vaccine doses per day. we prob need to get ~100-150M ppl vaccinated = 200-300M doses = 800-1200 days at current rate. last mile clearly a problem as many doses sitting with states, who have discretion over admin process.

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david friedberg

@friedberg

3 years

there isn't a lot of transparency or accountability in the vax rollout at federal/state/local level, but the US does have enough vax doses to effectively end the pandemic in 45-60 days. here's why, key metrics to observe, and a reminder on how we can do it...

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david friedberg

@friedberg

3 years

i’m thrilled for @metromile to be going public via SPAC $INAQ with @chamath leading the $160M PIPE alongside @mcuban and other leading investors. next step on what’s been a great 9 year journey. investor presentation w details:

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david friedberg

@friedberg

2 years

is this real? i think my faith in government may have just been (only partially) restored

The Recount

@therecount

2 years

Senate passes bill by unanimous consent to make Daylight Saving Time permanent. Sen. Kyrsten Sinema (D-AZ) seems excited about it.

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david friedberg

@friedberg

1 year

@Jason @ryanwcox @theallinpod @DavidSacks @chamath calling us “split” is reductive. the future is conditional. identifying, analyzing, and tracking those conditions is more relevant than what “side” someone is on.

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david friedberg

@friedberg

2 years

the $2T+ global beverage industry uses 100M+ acres of land, emits 500M+ tons of CO2, & creates 500B+ plastic bottles of waste each year. printing beverages at home would put a meaningful dent in this problem. i wrote more here..

Cana: Molecular beverage printers unlock the era of decentralized manufacturing

Cana, a TPB-incubated business, is on a mission to eliminate plastic waste.

link.medium.com

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david friedberg

@friedberg

1 year

it's usually the case that both things are (not) true

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david friedberg

@friedberg

4 years

"re-opening" is not a binary thing. People, Places, and Processes (PPP) define our current and future state. which people can go out, where they can go, what processes are in place when they do go out.

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david friedberg

@friedberg

2 years

one of our years-long projects at tpb has been to create a more resource/carbon efficient supply chain based on decentralized manufacturing... (1/3)

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david friedberg

@friedberg

3 years

absurd & obscene. after cancelling ONEM for some “out of turn” vaccinations (despite being one of highest throughput providers in state), CA now forcing all providers to use crappy accenture system ($100M no-bid contract for a website!) meanwhile, 2M doses sit on shelves in CA...

Eren Bali

@erenbali

3 years

We’ve been working with the City of LA & San Mateo County day and night to help deliver vaccines. Helped book 400k vaccinations and administer 250k. We provide both the tech & 100s of onsite clinical staff. Instead of supporting this, CA is throwing a huge curveball 1/5

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david friedberg

@friedberg

4 years

another paper published indicating 20-50% of ppl have T cells cross-reactive to SARS-COV-2 along with evidence this is due to prior exposure to common cold coronaviruses, potentially explaining why such a large % have low/no symptoms and recover quickly

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david friedberg

@friedberg

2 years

@Jason why can’t we ever have these conversations in private first?

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david friedberg

@friedberg

1 year

🤯

Curious Refuge

@CuriousRefuge

1 year

What if Wes Anderson directed The Lord of the Rings? We asked the community which video they want to see next and Lord of the Rings took the cake… or should we say Elven bread. We hope you enjoy this Midjourney to Middle-Earth. #LordOfTheRings #WesAnderson #MovieTrailer #LOTR

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david friedberg

@friedberg

3 years

COVID is causing 4k premature deaths + $3.3B loss to US GDP PER DAY. if we don't surge fast, imperfectly, decisively, today, the virus will evolve and we'll be stuck in an economic rut, as lockdowns + deaths persist for a long time. let's surge. let’s win the War!

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david friedberg

@friedberg

3 years

🙌 @GavinNewsom -- please publish your target throughput (vaccines/day) on these mass vaccination sites + how many more expect to open over time (+ pls open smaller sites at schools/parking lots). we really want to see a 45-day vaccination projection model for CA!

Gavin Newsom

@GavinNewsom

3 years

NEW: CA will be opening mass vaccination sites this week including Dodgers Stadium, Padres Stadium, and CalExpo. Our goal continues to be fast, equitable, and safe vaccinations statewide.

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david friedberg

@friedberg

1 year

@RyanCrownholm @theallinpod @chamath @Jason @DavidSacks @prenuvo really glad you caught it and are ok! such a great motivator to keep doing the pod. thanks for sharing

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david friedberg

@friedberg

1 year

"content" and "media" may end as terms, as we simply enjoy personalized experiences, not productize or distribute uniform consumables. centralized production for many is replaced by decentralized production for each individual human. should be fun.

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david friedberg

@friedberg

4 years

UW Virology has been testing symptomatic patients for coronavirus. they publish tests and results, in aggregate. here is the latest chart:

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david friedberg

@friedberg

8 months

The Changing World Order: Focusing on External Conflict and the Russia-Ukraine-NATO Situation

History is changing fast—in fact so fast that it won’t be long after you read this that dramatic changes will take place that will change the complexion of the world order. In this piece I’d like to...

www.linkedin.com

Elon Musk

@elonmusk

8 months

Why do so many American politicians from both parties care 100 times more about the Ukraine border than the USA border?

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david friedberg

@friedberg

2 years

for these reasons, and others (driven by various other science/eng advances), i am optimistic about mankind's ability to survive and thrive through the end of this century and well into the next, at which point, it appears far more than we can imagine today may become possible..

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david friedberg

@friedberg

1 year

100%

Elon Musk

@elonmusk

1 year

@WallStreetSilv It won’t get easier to pay down the debt. As debt rises for countries, interest payments consume a larger part of the budget, until there is little room for anything else. TANSTAAFL

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david friedberg

@friedberg

3 years

good. now they just need to commit to 1% of population (3M doses) per day and we can move on with life. administration should be able to get there by 3rd week Feb and we will be in the clear by early April.

CNBC Now

@CNBCnow

3 years

BREAKING: Biden to deploy FEMA, National Guard to set up Covid vaccine clinics across the U.S.

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david friedberg

@friedberg

3 years

even w small % of severe reactions, across 10-100M vaccinations, there will be thousands of bad reactions incl anaphylaxis and possibly deaths, maybe unrelated/coincidental. media will cover these anecdotes, driving anti-vax sentiment.. i hope we can counter this narrative

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david friedberg

@friedberg

3 years

you can’t make this up. the fact that members of Congress were assembling without taking $5 rapid antigen tests before entering the Chamber is unconscionable. $1T budget decisions. $5 tests to protect the ppl making those decisions.

Reuters

@Reuters

3 years

Three Democratic lawmakers announced they have tested positive for COVID-19 after being locked down with Republican colleagues, some of whom refused to wear a mask for hours as they avoided the mob that stormed the Capitol

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david friedberg

@friedberg

4 years

iceland has tested 10.4 people per 1,000 of their population - nearly double the rate of korea and the highest rate in the world. they started general population voluntary testing on friday

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david friedberg

@friedberg

7 months

"The two contend that America’s model of dispersed, consent-driven politics is deeply flawed and that centralized authoritarian systems are the most competent and efficient at managing modern societies. Unfortunately, as a recent Pew poll found, a growing number of Americans are…

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david friedberg

@friedberg

2 years

consumer credit bubble may be the next shoe to drop…

More Subprime Borrowers Are Missing Loan Payments

Strained by the end of pandemic benefits, consumers with limited or troubled credit histories are falling behind on payments for car loans, personal loans and credit cards.

www.wsj.com

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