Our 5-year work is finally out! We are able to engineer transplantable intestinal grafts using patient-derived
#organoids
and decellularized scaffolds with the hope to treat children with inesting failure.
@paolodecoppi
@Laween_Meran
Introducing new lab member... Baby no. 3 arrived on 24th Nov just after midnight. 4.4kg... definitely my new record! It was the most traumatic experience in my life.. but glad that we are both safe in the end! :)
Thank you
@guardian
for featuring our work on bowel cancer and organoid research
@TheCrick
and
@CRUKresearch
. Check out how stem cell technology crosstalks with cancer research.
Thrilled to announce that our lab will be funded by
@ERC_Research
#ERCCoG
to study the immunomodulatory role of WNT signalling in cancer
@TheCrick
. Come and join us for this exciting project! Openings will follow
Very honoured to be awarded the Women in Cell Biology Award
@Official_BSCB
. I am grateful to the Committee for their recognition of our team’s effort. Thank you to all our past and current lab members for their outstanding performance!
It's still medal season
@official_bscb
. Today we are very pleased and honoured to announce the 2021 winner of the WICB medal
@VivianLiLab
. Their work is inspirational. Learn more about it by visiting our website .
Excited to share our first publication this year
@TheCrick
.
@lnovellasdemunt
and colleagues showed in transgenic mice and patient-derived organoids that USP7 inhibition suppresses intestinal tumour growth without on target toxicity in normal intestine.
We are recruiting talented PhD student to join our lab this September to study intestinal stem cell lineage commitment. If you are interested please apply here 👇🏼
My 3 month old is starting nursery this week so that I can start focusing on science again. I do feel sad for leaving my little cherub to work.. wish I could see this smile all day long!
#WomenInScience
Thank you
@Official_BSCB
for safely delivering the medal to my office! Wish that I could attend the Paris meeting in person, but here we are. Looking forward to the virtual meeting.
Congratulations to our clinical fellow
@Laween_Meran
who just obtained her PhD degree! She is starting her new job in Oxford as NIHR Academic Clinical Lecturer in Gastroenterology from tomorrow. All the best!
📣 Postdoc position opening in the Li lab at the Crick!
We are looking for a highly motivated postdoc to join our vibrant lab! If you have cancer metabolism or multiomic analysis experience, please apply here! 👇
Closing on 31 Oct
@VivianLiLab
@TheCrick
Our latest (and last of 2019) story is out! We discovered new regulation of intestinal stem cell priming via Lgr5 degradation
@TheCrick
NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor | The EMBO Journal
📣 Very excited to share our latest findings!
Led by
@Nikos_Angelis7
, we found that ARID3A controls the "just-right" proliferation-to-differentiation ratio of the trans-amplifying cells in the intestine, important for homeostasis and plasticity
Research like mine
@TheCrick
depends on donations to medical research charities. These charities need Government support during these tough times.
@beisgovuk
please help protect
#ResearchAtRisk
Congratulations to our PhD student Sofia Pederson who passed her viva today! 🎓 Sofia took on a great challenge to perform multiomic analysis on stool samples and has done a fantastic job on data generation and analysis. We are very proud of you! Very well done!! 👏👏
Our first
#bioRxiv
about intestinal tissue engineering! This is a truely tour de force of 5 years work with fantastic collaboration across the
@TheCrick
and UCL. Special thanks to
@paolodecoppi
for the fantastic collaboration! Looking forward to the real publication!
Exciting opportunity to join
@VivianLiLab
!
We are looking for a highly motivated postdoc to work on immune evasion in colon cancer. If you have experience in cancer immunology, pls apply asap! Deadline is 31st July
Home schooling again in the next 10 days...
We can live with COVID, but why ditches mask when that's the least disruptive preventive measurement to reduce the spread? Just for personal comfort? Mask is only effective when everyone is wearing one. Not rocket science...
📢Job alert 📢
We are recruiting talented postdoc to join our lab! Multiple exciting projects available including study of cancer stem cell and impact of immune microenvironment in stem cell and regeneration. Computational biologist are welcome too! 👇🏼
This video clip was recorded before the lockdown. Glad to see that it's finally out.
#Organoids
research
@TheCrick
. Thanks
#CGTN
#Razor
for the production.
Growing mini organs to find new ways of fighting cancer: RAZOR via
@cgtnofficial
The Cancer Revolution exhibition is now in the London Science Museum
@sciencemuseum
! Great place to visit with your family during the summer holiday and check out the latest cancer research progress
@CR_UK
💬 “It’s important for people to see what exactly cancer research is” - Dr Vivian Li,
@TheCrick
We’re proud to be an expert partner of
@sciencemuseum
‘Cancer Revolution: Science, innovation and hope’ exhibition.
Read more 👇
Conversation with my 5.5yr old son today...
G: Mummy, where did the first person come from?
Me: (a bit shock but perhaps time to explain evolution) you know animals evolved over time...
G: I know about evolution, but where did the first animal come from?
(1/3)
Clinical PhD position opening! We are looking for motivated clinical PhD student to work on intestine engineering for transplantation and disease modelling. This is a joint PhD position working in both
@VivianLiLab
at
@TheCrick
and
@paolodecoppi
at
@UCLchildhealth
. Please apply👇
We're looking for clinicians who are passionate about research to join our 3-year fully funded clinical PhD programme 🔬🩺
Projects are available with
@ucl
,
@KingsCollegeLon
and
@imperialcollege
🗓️ Apply by 15 November 2023
📣 We are recruiting talented postdocs to join our lab to study WNT signalling and immune evasion. Come and join us if you are interested! Details can be found here👇
Our most senior postdoc Laura is leaving us after 6.5 years.. she is such an amazing scientist, colleague, friend, a highly valuable member of the lab who will be missed by everyone. Thank you for all your hard work and the laughter you shared. We wish you all the best!!
Mini-organs are no longer the stuff of science fiction,
@vivianlilab
will be on our engineering stage talking about how mini-organs have great regenerative potential for stem-cell therapy and organ reconstruction.
Get tickets now:
Only one more week to go before my talk about mini organs at the New Scientist Live. See you at the Engineering stage next week!
@newscilive
#NSLive2019
#organoids
2020 has been a roller coaster for everyone, particularly for working parents with young children at home. Not sure how, but we survived the
#pandemic
. Here are some highlights of the year from our lab, very much looking forward to 2021 when we can be back to normal again:
📝 *SAVE THE DATE!* 🗓️ The inaugural Wnt signalling UK meeting will take place on Monday 29th April 2024 at the
@TheCrick
institute, London.
Registration, abstraction submission and programme details coming soon.....
It was a great pleasure to host Mathew Garnett
@Garnettlab
at
@TheCrick
for our Cancer Interest Group series. Fantastic talk and impressive work on Cancer Dependency Map!
Join
@VivianLiLab
as she describes how scientists at the Francis Crick Institute investigating the biology of bowel cancer, by creating fully functioning mini-intestines on a microscopic scale.
Get your tickets here:
Me: ....well the universe is governed by physics laws and theories...
G: but where did the laws come from?
Me: ......(defeated..) go and ask your dad...
(3/3)
📣 We are recruiting talented postdocs to join our lab to study WNT signalling and immune evasion. Come and join us if you are interested! Details can be found here👇
Finally after being excluded for 3 years! Academia should not have been used as political negotiations in the first place. Glad that this is now resolved!
We have just reached a political agreement on the UK's participation in Horizon Europe and Copernicus.
It will allow the EU and UK to deepen their relationship in research, innovation and space, bringing together research and space communities. More ↓
Today is the last day of our very talented PhD student
@Nikos_Angelis7
, who has been with us for nearly 5 years. Very sad to see his leaving, but very excited for his next adventure!
Last official day
@TheCrick
after 5 years! Loads of emotions and great memories! Grateful for the people I met and collaborated. Special thanks to
@VivianLiLab
for being the best supervisor I could have asked for! Next stop:
@ZSAssociates
in London! Exciting!!
A great pleasure to participate in the stem cell podcast to discuss about intestinal stem cell research and tissue engineering.
@stemcellpodcast
@TheCrick
📣 We are recruiting new postdoc joining the lab to work on cancer detection and prevention. Please get in touch if you have experience on biomarker screening, metagenomics or metabolomics! 👇
Exciting opportunity
@TheCrick
to start your new research group here! The call is opened to early career scientists in all biomedical disciplines. Stem cell and cancer biologists, if you are finishing your postdoc pls do not hesitate for this amazing opportunity! 👇
Thinking about starting a group at the Crick? 💡 We're looking for creative researchers from all areas of biology and biomedicine to join our early career faculty community.
#AcademicJobs
|
#ECRChat
Learn more and apply by 6 October
🔗
Deadline is approaching on 31st October! If you are interested in joining the early detection of colorectal cancer project in our lab at
@TheCrick
, please apply! 👇
📣 Postdoc position opening in the Li lab at the Crick!
We are looking for a highly motivated postdoc to join our vibrant lab! If you have cancer metabolism or multiomic analysis experience, please apply here! 👇
Closing on 31 Oct
@VivianLiLab
@TheCrick
Applications for our 2024 PhD programme are open! Join us for…
🔬Innovative science
🗺️International, collaborative environment
🤝Structured programme, training and career support
💰£26,125 tax-free stipend + tuition and visa fees
Apply by 9 November ⤵️
The uncertainty of
@HorizonEU
@ERC_Research
negotiation continues amid the UK government crisis.... we need a clear plan from the government to continue the UK association to
@HorizonEU
and to support international research collaborations.
Check out the latest exhibition at
@TheCrick
- "Outwitting Cancer", featuring multiple cancer research labs with some personalised video clips. Fantastic effort from our Public Engagement team! Booking is now opened 👇🏼
📣 Postdoc opportunity!! 📣
We are looking for talented computational biologist to join our multidisciplinary lab for some exciting projects about intestinal stem cell and cancer. Details can be found 👇
Another fantastic open exhibition at
@TheCrick
, this time is about gene editing. Come along and explore the featured gene editing work here at The Crick!
Our free hands-on exhibition
#CutAndPaste
created by
@TheLiminalSpace
opens TODAY. Come explore the big questions around the ethics of genome editing and tell us where you would draw the line 🧬✂️
🔗
My
#lockdown
solution to
@BorisJohnson
: be bold and decisive; start making millions of reusable masks; once the cases have gone down, distribute and ask everyone to wear those masks when going out, in public transport or even at work; penalty in place if not complying.
In addition to the conventional self-renewal and multipotnecy properties, we discuss other molecular definition of the ISC identity based on their distinct cellular states.
Very excited for the establishment of the WntUK Network
@UK_Wnt
. Would be a fantastic platform and opportunity to connect and strengthen the Wnt reseach in UK! 👇👇
We are super excited to announce the long overdue creation of a UK Wnt signalling research network. Currently comprised of 24 labs across the isles but seeking more - please email WntUK2023
@gmail
.com to join! Check out our first newsletter below 👇 👇 👇
Huge congratulations to Crick group leader
@VivianLiLab
, winner of this year's Women in Cell Biology Early Career Medal from the
@Official_BSCB
! 🎉🍾🏅
Find out more about Vivian’s work and the award on the
@Official_BSCB
's website ➡️
Me: ... (OK bigger picture) when the earth and solar system was formed...
G: but where did the first planet come from?
Me: ... (starting to feel out of my comfort zone...) you know there was the Big Bang theory....
G: but where did the Big Bang come from?
(2/3)
In our latest blog post, we look at bowel scope – a test used for bowel screening that
@NHSEngland
have announced will no longer be available in England. Read more about what these changes to screening mean for patients 👇
📢Job alert 📢
We are recruiting talented postdoc to join our lab! Multiple exciting projects available including study of cancer stem cell and impact of immune microenvironment in stem cell and regeneration. Computational biologist are welcome too! 👇🏼
In a major scientific breakthrough, the latest version of
#AlphaFold
has been recognised as a solution to one of biology's grand challenges - the “protein folding problem”. It was validated today at
#CASP14
, the biennial Critical Assessment of protein Structure Prediction (1/3)
Dame Deborah James is truely inspirational. There is still a lot more to do to fight bowel cancer, a potentially preventable disease if diagnosed early.
#bowelcancer
#bowelcancerawareness
We’re deeply saddened that our patron,
@bowelbabe
, has died, and our hearts go out to her family and everyone who knew and loved her. Deborah’s star shone bright; she was a true inspiration to so many.
Check out this Year in Review from Dr. Vivian Li on disease modelling using gut organoids, AND make sure to tune into the podcast on January 12th to learn more about Dr. Li's research!
📣 We are recruiting new postdoc joining the lab to work on cancer detection and prevention. Please get in touch if you have experience on biomarker screening, metagenomics or metabolomics! 👇