Male placentas produce more proinflammatory molecules than female placentas, while pregnant people carrying male fetuses produce fewer antibodies in response to infection.
As an assistant professor at MD Anderson Cancer Center,
@Debeblab
uses mouse models to look for similarities among tumors that metastasize to the brain.
New: A subset of people who contracted COVID-19 still have symptoms months later, leading some researchers to suspect the illness can spark long-lasting disease.
A new study suggests that neurotransmitters released during stressful experiences cause immune cells to stop in their tracks rather than patrolling the body to identify and fight invaders.
“I hear that paleontology has always been this way; it’s not going to change. But we must start somewhere.” —Juan Carlos Cisneros, Federal University of Piauí
Yesterday in
@TheLancet
researchers published preliminary results from early stage trials for two vaccine candidates. Both appear to be safe and to elicit an immune response in people.
The Pfizer and Moderna shots work completely differently than the J&J and AstraZeneca vaccines, which have been making news over rare instances of blood clots. More via
@nytimes
:
Chantell Evans (
@channyskye
) uses live-cell microscopy and proteomics to study mitochondrial quality control and its role in neurodegenerative disease.
@EvansLab
@DukeU
Autopsies recently carried out in California show that at least one person died of the disease on February 6—three weeks before the country’s first fatality was reported.
“These two papers add to a weight of evidence that viruses—and pathogens in general—must now be seriously considered as causal agents in Alzheimer’s disease."
People who became infected with SARS-CoV-2 after receiving one dose of Pfizer’s COVID-19 vaccine harbored about four times less virus than did unvaccinated people who caught the virus.
Following the success of
#BlackBirdersWeek
, Black botanists are using their week of celebration to pay tribute to Lynika Strozier, who died of COVID-19 at age 35.
#BlackBotanistsWeek
Via
@wttw
(1/2):
The journal PNAS has temporarily banned a researcher from submitting manuscripts following a dispute about access to materials used in a scientific article.
“This is the first effort that truly comports with the needs of people who are suffering,” Survivor Corps’ Diana Berrent (
@dianaberrent
) tells the Associated Press (
@AP
).
Early-career scientists are often expected to uproot their lives for a two- or three-year position. Meet the researchers opting for remote postdocs instead.
A single gene can be spliced differently to generate up to 38,000 distinct transcript isoforms, and each of the proteins they produce has a unique function.
“We now have a parts list of the brain,” said
@HongkuiZeng
@AllenInstitute
.
She and a network of researchers unveiled a cellular map of an adult mouse brain by identifying more than 5,300 cell types.
Check out the kaleidoscope of neural diversity:
Tatsuya Nobori (
@nobolly
)
@salkinstitute
developed PHYTOMap, a new method that revealed dozens of plant genes in stunning 3D detail.
Exploring this genetic landscape helps researchers gain insights into mechanisms behind plant adaptability.
Researchers have dug into massive gene expression datasets to show that human cells producing ACE2 and TMPRSS2 are scattered throughout the body—including in the heart, bladder, pancreas, kidney, and nose. There are even some in the eye and brain.
In a trio of studies, researchers follow up on a 40-year-old finding that certain bacteriophages replace adenine with so-called diaminopurine, perhaps to avoid host degradation.
Franklin's sister: "She could never have imagined that over 60 years later there would be a rover sent to Mars bearing her name, but somehow that makes this project even more special." Via
@BBCScienceNews
Collaborations with Johnson & Johnson and Moderna are meant to prepare the companies to produce vaccines in mass quantities if a safe and effective option is approved.
Our 3rd most-viewed infographic of the year: The COVID-19 pandemic is sparking renewed efforts to study the underlying causes of this complex, debilitating disease, which might be triggered by the novel coronavirus.
#countdown
“Researchers, we always go back to work before everybody else because of the nature of our work; if this was not important, we wouldn’t be doing what we’re doing.” —Carmen Maldonado-Vlaar
PHYTOMap is a new technique developed by researchers
@salkinstitute
that shows the insides of plants in 3D by mapping a colorful array of gene expression for a more complete understanding of how plants react to their dynamic environments.
#SpatialBiology
This 👉🏾 studying the regulation of these genes in the germline and across generations, we could examine if behavior can be controlled transgenerationally. 🤔💭
Our June issue reexamines some of our assumptions about living with microbes, asking whether cooperating with pathogens is sometimes a better strategy than fighting them. We also delve into how "good" bacteria may contribute to autoimmunity—and much more.
“The idea that cardiovascular disease, the first cause of death in the US and worldwide, could be cured instructing T cells to kill detrimental cells is revolutionary.”
This month’s Scientist to Watch, Adriana L. Romero-Olivares (
@fungi_lover
), “represents the next generation of women in science.” —
@CamilleDefrenne
,
@ORLN
BREAKING NEWS:
The 2020
#NobelPrize
in Chemistry has been awarded to Emmanuelle Charpentier and Jennifer A. Doudna “for the development of a method for genome editing.”
Hundreds of scientists around the globe are launching studies in search of genes that could explain why some people fall victim to coronavirus infection while others escape relatively unscathed.
"When he showed a picture of himself holding the Indian flag with white snow all around, the audience got goosebumps. The kids clamored to know more." —Karishma Kaushik
@KaushikLab
“If we don’t describe it, it’s just going to stay this way—undescribed—and we’ll be calling it ‘ctenophore A’ until something happens.” —Christopher Mah, Smithsonian National Museum of Natural History/
@echinoblog
A small study of macaques finds they don’t develop a coronavirus infection the second time they are exposed, supporting the idea of using plasma from recovered patients as a treatment for COVID-19.
In our October issue, we take a look at air pollution's effects on the brain, a new way of thinking about the origins of Parkinson's disease, and much more.
The symptoms suggest SARS-CoV-2 might infect neurons, raising questions about whether there could be effects on the brain that play a role in patients’ deaths, but the data are preliminary.
@cannemckenzie
Our Editorial team, which is predominately female and more than half of whom are mothers, made the decision to recognize that trans men and nonbinary people can have children in our reporting. Women are people. The post is factually correct.
"Saying that most experiments in mice don’t translate to human beings doesn’t quite get the point across. It’s more correct to say that almost none of them do." Via
@statnews
Mutations to the virus happen at a rate of about one a month. They usually are completely inconsequential, but the NextStrain team is keeping an eye on mutations that might make a difference in virulence or other factors important for human health.