Researchers at MIT grew wood-like plant tissue in the lab, which, if scaled up, could perhaps one day lead to the development of lab-grown wood, fiber, and other biomaterials aimed at reducing the environmental footprint of forestry and agriculture.
"I use tobacco plants to produce antibodies for drug development, to fight diseases including cancer and COVID-19. We introduce the genes coding for the pharmaceutical proteins and the plants make them." - Audrey Teh, molecular immunologist
Big news for
@EligoBio
: a $224M deal with
@GSK
! 👏 The company's
#CRISPR
-based acne treatment disables harmful bacterial genes that induce acne while leaving the rest of the skin
#microbiome
intact! 🦠
Meet the scientists who created the first open-source COVID-19 vaccine: These two infectious disease experts worked fast to create an effective COVID-19 vaccine, get it manufactured, and then give it away to the world, patent-free.
What are the defining milestones from the last 20 years of
#syntheticbiology
?
Tim Gardner,
@riffyn
founder and CEO, will be highlighting the community’s view of the defining moments in the history of
#synbio
at
#SynBioBeta2018
. Watch the live stream Oct 3
.
@CurlyJungleJake
is an admirer of the human immune system — but he thinks we can do better. His company
@centivax
announced that they have created optimized antibodies that protect hamsters from lethal amounts of the virus that causes
#COVID19
.
Researchers made golden rice extra gold with
#CRISPR
: Using this technique, drought- and pest-resistance genes could be inserted into food crops to make them more productive
You probably know what Rosalind Franklin did for science. But you should know these pioneers too. In honor of
#InternationalWomensDay
, meet three overlooked scientists who blazed trails for modern synthetic biology 👩🔬
#IWD2021
#WomensHistoryMonth
Researchers have just
#engineered
E. coli to produce chondroitin sulfate, a drug best known as a dietary supplement to treat arthritis. Currently, it's sourced from cow trachea. How else can therapeutics be animal-free? 🦠 👩🔬
#synbio
#MicrobeMondays
An enzyme could make a dream come true for the energy industry: It can efficiently produce hydrogen using electricity and can also generate electricity from hydrogen.
It’s the largest Series A in
#foodtech
history:
@Ginkgo
Bioworks announced the $90 million launch of
@proteinmotif
, a spin-out company that aims to provide next-generation alternative
#proteins
and other ingredients to
#food
companies worldwide.
#synbio
#Culturedmeat
, produced in bioreactors without the slaughter of an animal, has been approved for sale by a regulatory authority for the first time. The development has been hailed as a landmark moment across the meat industry.
#cellbasedmeat
#foodtech
Two decades of breakthroughs in
#neuroscience
and
#syntheticbiology
are merging, giving rise to new technologies that can potentially treat neurological diseases and even enhance cognitive abilities. Watch the
#synbiobeta2018
live stream Oct 2 at 8:30 am
.
@DARPA
has awarded
@Ginkgo
Bioworks,
@azitrainc
, Latham BioPharm Group, and Florida International University (FIU) a contract of up to $15 million to create a novel, long-lasting mosquito repellent using engineered microbes:
@MattDeGennaro
@twhitfill
Adidas is going plant-based. 🌱
The athletic-wear company announced on Monday that it's working on a new material, a
#plantbased
leather that will be used to make shoes. 👟
Scientists in Europe and the US are reporting what they describe as the first successful use of optogenetics to improve a person’s vision. The feat involved introducing a gene from algae into the man’s retina.
Northwestern University synthetic biologists have developed a low-cost, easy-to-use, hand-held device that can let users know—within mere minutes—if their water is safe to drink.
#synbio
A virus-like COVID-19 vaccine is being grown in tobacco plants.
The “virus-like particle” produced by the Canadian company Medicago is the only vaccine in clinical trials made in plants
Researchers have achieved a significant milestone by successfully integrating more than seven synthetic chromosomes into a single yeast cell, yielding a strain with over 50% synthetic DNA that can survive and replicate similarly to wild yeast strains:
Can bacteria make materials that are strong, tolerant and resilient? We have a long history of using microbes as factories—for example, using yeast to make beer. But there is limited research on using microorganisms to manufacture engineering materials.
A team of researchers has engineered an entirely new biochemical pathway that incorporates the carbon of CO2 into molecules critical for the cell's basic metabolism.
"Synthetic biology is among the most hyped research topics this century, and in 2010 it entered its teenage years. But rather than these being a problematic time, we’ve seen synthetic biology blossom and deliver many new technologies and achievements."
"Artificial photosynthesis is ten times more efficient than natural photosynthesis. In 2021 we will begin to explore practical ways to scale up the technology."
#renewableenergy
#sustainableenergy
Kids &
#Coronavirus
town hall - Now also joined by Sarah Ives, Director at Distributed Bio and star of the Netflix documentary series “Pandemic: how to prevent an outbreak"
@sives54
@distributedbio
#covid19
.
@asimov_io
is building a full-stack genetic design platform to program living cells.They are integrating mammalian synthetic biology w/ computer-aided design to advance therapeutic applications. CEO Alec Nielsen will be talking about it at
#SynBioBeta2020
The number of applications where biotechnology could make a difference towards sustainability is virtually unlimited. Here are 10 of the areas where biotech is already making an impact.
Can you believe synthetic biology companies raised nearly $8 billion in 2020?👏 See how
#biotech
reached record investments in the middle of a pandemic and what this could mean for 2021. What do you think will be this year's hottest
#synbio
trend? 🔥👩🏿🔬👩🏿🔬
Researchers have found a way to increase protein production up to a thousandfold, a discovery that could aid production of proteins used in the medical, food, agriculture, chemical and other industries.
#synbio
#biotech
#biotechnology
#biology
#biobased
Bioengineers have found a simple solution to the problem of precisely regulating the expression of synthetic inducible genes through harnessing the central dogma at the levels of both RNA and protein synthesis.
“Biology will undoubtedly fuel computing” in coming years,
@ericschmidt
said at
#SynBioBeta2019
. “Taking
#biology
, which I’d always viewed as squishy and analog, and turning it into something that can be digitally manipulated, is an enormous accelerator.”
This week, we spoke with
@jrkelly
of
@Ginkgo
about synthetic biology’s coming of age", the history of programmable biology, the role of AI in biology, and the new congressional commission covering national security and emerging biotechnology.
Jurassic Park for Perfume:
@Ginkgoo
Bioworks Reconstructs Scents From Extinct Plants
Synthetic biologists resurrect fragrance-producing genes from bygone plant species
#synbio
#syntheticbiology
Anna Marie Wagner (
@AnnaMarieWagner
) from
@Ginkgo
speaks with Rory Kelleher from
@nvidia
about digitizing biology using AI models and deep learning enabled by computing power that has recently scaled at orders of magnitude.
#AI
#synbiobeta2024
Going “Cell Free” Can Put a Rush on
#COVID19
Antibody Therapies:
SwiftScale Biologics has a
#cellfree
protein production platform that can speed development and manufacturing scale-up
A research team led by Northwestern and Cornell universities has developed a new manufacturing platform that can quickly make vaccines at the point of care, ensuring they will not go to waste and expanding access to potentially life-saving medications.
Under a new deal,
@Ginkgo
will acquire 100% of Utrecht, Netherlands-based Dutch DNA Biotech, a contract manufacturing organization that makes enzymes, proteins and organic acids using its fungus-based technology.
#synbio
Discovery allows bioengineers to compose genetic programs using
#syntheticbiology
. “With this new capability, we have taken a big step in being able to truly engineer biology,” said Northwestern University synthetic biologist Joshua Leonard 👏
#synbio
The natural world is a treasure trove of potentially useful enzymes, hidden in microorganisms living all around us. But finding them is tricky. A team of researchers at NTNU have developed a new method to break open cells that could help in the quest.
Through biological engineering,
@Ginkgo
design custom organisms to create new products with the potential to transform industries. Today the company announced the Series E financing round totaling $290m, with all their existing investors participating
Although gene circuit engineering has progressed more slowly in mammalian cells than in yeast cells and bacterial cells, researchers are optimistic that synthetic gene circuits can be used to turn mammalian cells into platforms for varied applications.
"Young synthetic biology companies raised nearly $8 billion last year from venture capitalists and IPOs worldwide, more than double the level in 2019, according to SynBioBeta. This year, total funding could surpass $30 billion, SynBioBeta predicts."
The
#synbio
industry’s platform of platforms
@Ginkgo
and pharmaceutical giant
@novonordisk
are developing a way to make better drugs that can actually be manufactured. Check out our latest insight piece:
Several startups are now pursuing the potential of enzymatic synthesis as a faster and more efficient route for synthesizing longer DNA sequences than is possible with traditional chemical means.
.
@sives54
is the lead scientist for the broad-spectrum
@centivax
flu vaccine technology awarded a Global Grand Challenges "Ending the Pandemic Threat" grant from the
@gatesfoundation
. She will be speaking at
#SynBioBeta2020
.
@biogen
and
@Ginkgo
announced a
#genetherapy
collaboration. Together, the companies aim to redefine the industry standard for manufacturing recombinant adeno-associated virus (AAV)-based vectors.
#synbio
After 2 decades of growth and success,
#syntheticbiology
has now become a mature field that is driving significant innovation in the
#bioeconomy
and pushing the boundaries of the biomedical sciences and biotechnology. So what comes next?
#synbio
🔬🦠🧬
The first two decades of synthetic biology were ruled by microbes. 🦠
But now,
@bitbio
is giving cells new identities through its platform, opti-ox, and radically reimagining what is possible with the engineering of mammalian cells:
What does the global
#bioeconomy
look like in 5, 10 or 20 years? What are the key cases of microbial-enabled manufacturing, how should they evolve in the coming years? Join the discussion at
#SynBioBeta2018
, early bird ends today:
#synbio
#biotech
In a new study, scientists have developed cells which can be reprogrammed to perform new tasks. Simple Cells or ‘SimCells’ are an entirely new platform for synthetic biology with exciting prospects.
#synbio
A research team has resurrected several-billion-year-old enzymes and reprogrammed them to catalyze completely different chemical reactions than their modern versions can manage
Synthetic biology researchers at Northwestern University say they have developed a system that can rapidly create cell-free ribosomes in a test tube, then select the ribosome that can perform a certain function.
#synbio
“It’s Silicon Valley investing in the next big thing, and the next exciting thing, and paying it forward to the next generation of entrepreneurs,”
@johncumbers
explained during a recent GEN Live focused on synthetic biology’s growth and challenges
#synbio
Unlike many other synthetic biologists who are working to enhance or genetically engineer microbes directly, Daniel Segrè is more interested in how to direct the behavior of a microbiome by tweaking the environmental conditions it lives within
Many of today’s most trusted drugs are so notorious for their wide range of potentially serious adverse reactions, they are known in the business as “dirty drugs.”
#Syntheticbiology
company
@OctantBio
has developed a better way to design drugs:
@srikosuri