@beale_md
Before everyone jumps on the myocarditis, it is important to note that in autopsy (not biopsy) report from China there is no inflammatory cell infiltrate but lots of endothelial sloughing. Need 2 consider ischemic microvascular thrombosis. Probably why they lyse instead of PCI.
For anyone not familiar w why the killing in Atlanta has struck a nerve w Asian, Asian American Pacific Islanders, take a few min 2 read this article by the Dean of
@UCBerkeleySPH
Michael Lu. It describes both personal & historical perspective on this issue.
@JoyYWu
@StanfordCVI
Thanks a bunch June!! Serving on the
@BCVSearlyCareer
committee & leading it through the pandemic has been the most meaningful part of my role as a lifelong AHA volunteer. I am so honored 2b recognized for it & want to share it w my committee 4 their hard work in the past 2.5 yrs
Woohoo!!!
@SeanM_Wu
is receiving “2022 distinguished achievement award” for his leadership in BCVS! So grateful to know you and huge congratulations!!
@StanfordCVI
Congratulations to
@JoyYWu
for receiving the 2021 Allyship Award by the
@stanford
Faculty Women's Forum for "leadership in advancing an equitable and inclusive academic culture for women and Asian Americans through mentoring, recruiting, advocacy.."
@StanfordDeptMed
@StanfordMed
New from
@SeanM_Wu
& Co: Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes
Just made it through a home-made haircut by
@JoyYWu
after giving minimal instruction. I think I’ve uncovered a new talent in her. Don’t you agree? Now booking new appt for after shelter-in-place. Hmm..where did she get trained for this? 🤔Her Osx-GFP 🐭?😳
Woah! This is among the wildest papers I've read in a long time. Freeze-dried somatic cells were nuclear transferred into oocytes 2 make cloned blastocyst then ESCs for re-cloning into mice.
Healthy cloned offspring derived from freeze-dried somatic cells
Very excited 2 share our new work by
@fxgaldos
on "devCellPy - a machine learning-enabled pipeline.." where we created a software 4 automated & highly accurate multi-layered annotation of time & location-dependent cell types from scRNAseq data
@StanfordMed
@JimZarroli
V important to understand RIGHT NOW-the US rate of rise in COVID-19+ people is higher than Italy meaning we will hit a # bigger than 25K in the next 3-4 days w 2%-5% death rate. Make sure everyone in NYC
#StayTheFHome
& practice
#SocialDistancingNow
to
#FlattenTheCurve
Thanks
@JoyYWu
for your uncanny ability to make me look better than I really do. 😘 The kids faces tell the real truth-they weren’t so sure this was a good idea, both in the picture and IRL.
#HappyFathersDay2021
Counting down the last hr of 2020 on the West Coast. Lots 2 reflect on & much to forget. I am so grateful 2 all the colleagues on the frontline fighting COVID & proud 2 be a scientist in a yr where ppl got 2 truly 👀 the importance of science. Much hope for a better 2021 to all!
Super proud of my wife/best friend/better half
@JoyYWu
for speaking out and encouraging
#BreastCancerAwareness
among all women. 💪💪💪👍👍👍 It’s never too late to get checked. May save yours or someone else’s life one day.
I had no family history, no risk factors for
#breastcancer
, and saw no need for a mammogram for a few more years. Thank heavens my PCP ordered one anyway, which led to my diagnosis and may have saved my life.
#BreastCancerAwarenessMonth
A
@NIGMS
grant will fund multidisciplinary, multi-institutional research aiming to understand the common cause of heart failure.
#StanDOM
's
@SeanM_Wu
is one of three
@StanfordMed
scientists leading the project.
Our acutely symptomatic shower drain underwent a rotational atherectomy & thrombus aspiration this am resulting in TIMI3 flow immediately after. I have a new level of appreciation for our interventional cardiology colleagues. 🙏😉❤️
Is the reviewer 2 position reserved 4 someone who has had a bad day? Finally got around 2 look at the summary statement from an NIH grant that got triaged twice. Something to be said about a process where you can get both 1 and 7 for "Candidate" from different reviewers. 🙄
Wu family tradition continues in 2021 -
#SuperBowl
snack stadium! What used to be Patriots vs Rams/Falcons/Seahawks is now replaced with Brady vs Chiefs.
#TomBrady
#gronkowski
While the omicron surge & grant writing made the month of Jan went by in a blur, it’s nice 2 have had a month of continuous sunshine
@skiheavenly
. It never gets old 2 see this view…and you don’t need 2 shovel what’s in your driveway.😜
@JoyYWu
@ArunSharmaPhD
@StanCVFellows
Congratulations to Dr Christine (Kricket) Seidman for receiving the AHA distinguished scientist award at
#AHA22
@AHAScience
. Her discovery of the genetic causes for HCM, DCM, and congenital heart disease have paved the way for myosin specific new therapies.
@American_Heart
Wow! A new entity
@stanford
research park w $650M donation that brings together scientists from 3 premier Bay Area research institutions w the goal to develop innovative new treatments for devastating diseases. Great opportunity 4 physician-scientists!
Thanks to
@StanfordHealth
RN and staff for their hard work during the holiday wkend to vaccinate as many healthcare & essential workers asap. With the rising Bay Area case count, it is crucial 2 protect frontline personnel. Look forward 2 start inpatient card consult next wk.
Great to see you @
#BCVS22
@SoahLeePhD
! The lab got me this world map to point out where our lab members are located now. I can’t wait to see what you all will be able to accomplish in your own labs. Congrats on your award
@BCVSearlyCareer
poster competition!
@AHAScience
Sean Wu Lab Dinner at Chicago
#BCVS22
.
@SeanM_Wu
turned three postdocs ➡️ professors at three different continents. 🙌🏼. So grateful to have colleagues like
@HanZhuMD
and Jan Buikema along the journey.
While lecturing @ Shanghai Med School, my host Prof Wang gave me a tour of Suzhou & taught me the Chinese saying "In sky heaven, on earth Su(zhou) Hang(Zhou)". The gardens are beautiful as are the people. Definitely worth a stop for anyone visiting China.
#AcademicTwitter
For those who are members of
@TheEndoSociety
make sure you vote for the next President-Elect when the ballot opens in November. Both choices are great but one clearly stands out in my mind. Anyone care to guess who that is? 😉
Election ballot GOALS 🤩!
So proud of the Endocrine Society and its amazing leadership
@JoyYWu
@StephenHammes
(And congratulations to
@Jenny_A_Visser
and the Nominating Committee for a fantastic slate of nominees)
Calling all AHA BCVS early career members-Don't miss out on 👇 exciting events designed 4 early career BCVS virtual meeting attendees. Happy hour/social networking incl. ice breaker game & mentoring breakout sessions
@AHAMeetings
@AHAScience
@AHA_Research
@nhpetunia
@StanfordCVI
Haifan is among the most outstanding scientist whom I’ve met. Shame on you
@Yale
for presuming him guilty before due process has been completed. I call on
@ISSCR
@ASCBiology
and other organizations to take a stand against this injustice.
The faculty in
@YaleCellBio
and
@YaleSCC
strongly support our colleague Haifan Lin and his entire research group in the wake of his administrative suspension by
@Yale
, a step taken without any formal charges or due process. See our statement 👇👇
As a physician-scientist, I've tried hard to avoid politics in
#SoMe
but after working 18+ hr/day for past wk learning & educating my
@stanfordMed
colleagues on
#Covid_19
, while covering inpt card consult,👇crossed the line. Maybe we should call it
#TrumporonaVirus
?
@choo_ek
Desperately trying to hold on to his chances of re-election, he relies on his tricks of race-baiting and bigotry catering to his base- Photo of Trump remarks shows 'corona' crossed out and replaced with 'Chinese' virus
Getting started with
@StanfordMed
graduation ceremony. Very hot day for sitting outdoors but glad that someone thought to provide personal fans to keep cool.
@JoyYWu
@fxgaldos
Thanks 2
@Joseph_C_Wu
I got a seat @ the AHA President & Chairwomen Marsha Jones’ Dinner tonite @ Mutter Museum in theCollege of Physicians of Philadelphia. It was great meeting up w mentors Dr Victor Dzau, Ivor Benjamin,
@HeartBobH
, & friends Joe&Amy Woo, Jay&Amy Zhang, C-PChang
This
@KeystoneSymp
mt in Santa Fe, NM will be awesome! Pls check out the speaker line up & submit abstract 4 short talk & workshop panel spots. My lab is also planning a ski trip to Taos in conjunction. Would be fun to see lots CV scientists there 4 great science & social.
This was a great collaboration between cardiologists and immunologists to understand the potential mechanisms of SARS-CoV-2-mediated cardiovascular damage. Thanks
@HanZhuMD
for the great work putting it all together.
@Ron_Witteles
@JuneWRhee
@Paul_P_Cheng
Our paper on COVID-19 and CV complications/host immune response is now live!
#Cardioimmunology
can give us powerful tools to study the effects of the immune system in the heart in topics ranging from cancer therapies to infectious and autoimmune disease
Finally got to sit & enjoy a relaxing bkfast/brunch after inpatient cards service
@StanfordMed
for the past 2 wks. Really 🙏 the hard work of
@StanfordMedRes
Adrian Castillo,Alejandro Vallar-Padros,Jaron Yang & all the RN/staff on J7,M7 @ new hosp. I’m RSVP Rm J718 if I get sick
Final call 4 registering 2 attend the
@AHA_Research
@BCVSearlyCareer
Committee Virtual Mentorship Seminar on "You're Hire - Standing Out in Your Interview & Job Talk". Breakout sessions 4 Assist Prof & Post-doc applicants. Come get your ?s answered on impact of COVID on hiring.
"The origins of the Asian American diaspora itself have direct legacies to the long histories of occupation, colonization and wars in Asian countries, such as the Philippines, Korea, Vietnam and elsewhere."
Excited to see my college friends
@stanford
reunion homecoming this weekend. Hard to imagine it’s been 30 yrs. Lots to reminisce and reconnect w classmates whom I haven’t seen in decades.
@JoyYWu
@StanfordEng
@StanfordMed
We treat our Early Career Members with lobster Mac’nCheese, clam chowda, and fancy desserts! Nothing but the best for our future basic and translational CV scientists. Grand Ballroom C-E.
#BCVS19
@AHAMeetings
@AHAScience
@AHA_Research
It was super fun 2 do this podcast w the all star team of
@ArunSharmaPhD
& Daylon James. 👇 is where u find out why the “cardiopsychiatrist” mug sits on my office shelf. Although I can’t claim RVU 4 any of my office time, it was the most rewarding part of being a lab PI
@stanford
Next week's podcast guest is Dr. Sean Wu (
@SeanM_Wu
) from
@StanfordMed
. Check out his recent paper in
@CircAHA
, in which patient-derived iPSCs were used to implicate intrinsic impaired contractility in hypoplastic left heart syndrome. 🫀
Read the paper:
Wolfram Zimmermann discuss engineered heart tissue transplant into pts with chronic heart failure. Already enrolled 53 pts so far in Germany w no adverse events reported @
#KeystoneSymposia
Cardiac Dev & Dz.
@Joseph_C_Wu
Excellent 🧵 for anyone starting up on her/his MD-PhD app cycle this year. Having been on MSTP committees 4 more than 20 yrs & mentoring undergrads into MSTP programs, I think this is one of the best, if not THE best, take on how to approach the MSTP app process.
#Itsthejourney
Nobody:
Absolutely no one:
Me: Here’s a 🧵 with my thoughts/advice on MD-PhD admissions (from start to finish)
As the next app cycle begins, I'm just hoping to help others avoid the traps that I fell into
This is all n=1, so feel free to chime in if you agree/ disagree
(1/25)
Dr Jacob Schroder, surgical director of cardiac transplant
@DukeMedSchool
, discussing DCD donor heart transplant history & outcomes
@stanford
-Duke-Penn-Cornell CV Symposium. Significant promise for expansion of DCD heart transplants in the future w OCS use.
@StanfordCVI
With all the recent
#AcademicTwitter
discussion on whether or not to do an academic post-doc, this
@BCVSearlyCareer
seminar should be of great interest to many. Come find out the career paths of scientists in government labs, industry, publishing, and foundation/philanthropy.
Congrats to
@DukeMBB
team for the great win over Arkansas tonight 78-69. Onward to New Orleans for a trip to the
#FinalFour
. The G.O.A.T. lives on to claim his 6th NationL Championship title.
#MarchMadness2022
#chasecenter
How can “Targeting Mitochondrial Dysfunction to Prevent Heart Failure in
#SingleVentricle
Congenital Heart Disease” uncover new risk biomarkers? Sharon Paige,
@SeanM_Wu
, &
@Tahmina_Samad
@Stanford
will use their SVRF award to find out & explore novel nutritional interventions.