wyomingwormboy @wyomingwormboy Twitter profile

Last Seen Profiles

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wyomingwormboy

@wyomingwormboy

3 years

So what happens if you get your first covid shot, but then a shark bites your arm off just above where the needle went in, like about 47 minutes after you got the shot? Does that dose still count? As a scientist I need to know these things.

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wyomingwormboy

@wyomingwormboy

3 years

This is the reason to have undergrads in the lab.

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wyomingwormboy

@wyomingwormboy

3 years

Likely the greatest discovery in the history of nematodes. A worm that makes star shaped tracks! (credit, P. Edeen)

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wyomingwormboy

@wyomingwormboy

4 years

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wyomingwormboy

@wyomingwormboy

1 year

Questions for faculty candidates at chalk talks: 1) Of the faculty you’ve met so far, whose research did you find most boring? 2) Would you rather be attacked by 3 small sharks or one really big one? 3) What is your plan if none of your experiments work for the rest of your life?

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wyomingwormboy

@wyomingwormboy

4 years

It’s high time that PIs took a unified stand on this issue.

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wyomingwormboy

@wyomingwormboy

2 years

Do labs in the UK get their enzymes from Old England Biolabs?

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wyomingwormboy

@wyomingwormboy

3 years

The Whole Whorton Threaded.

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wyomingwormboy

@wyomingwormboy

3 years

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wyomingwormboy

@wyomingwormboy

2 years

From now on when people say they have a significant other, I want to see the damn p-value.

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@wyomingwormboy

4 years

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@wyomingwormboy

3 years

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@wyomingwormboy

3 years

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wyomingwormboy

@wyomingwormboy

3 years

A short thread about faculty and workloads: In my experience, most faculty who admit to feeling grossly overworked (🖐) don’t do it for some perverse sense of glory, martyrdom, or twisted enjoyment. We do it because the job seems to require it. Quite often it turns out. 1/3

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wyomingwormboy

@wyomingwormboy

3 years

This one’s short, silly and pointless.

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wyomingwormboy

@wyomingwormboy

3 years

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wyomingwormboy

@wyomingwormboy

3 years

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wyomingwormboy

@wyomingwormboy

2 years

Faculty at non-R1s spend a lot of time vetting & training students. The successful ones often go on to R1s, where those faculty reap the benefits. It’s all good, but it takes a toll on our publication output. Please consider this when judging our productivity and contributions!

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wyomingwormboy

@wyomingwormboy

3 years

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wyomingwormboy

@wyomingwormboy

3 years

One difference between science now and 20-30 years ago is that I can essentially read an older full-length article in 10-15 min. New articles I need a week. And the number of articles I should be reading has also increased 10-fold.

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wyomingwormboy

@wyomingwormboy

3 years

I’ve officially forgotten how to not work on weekends. Weekends appear to be for catching up on work I didn’t get done during the week.

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wyomingwormboy

@wyomingwormboy

1 year

When the light source costs 10x more than the scope ($69)!

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wyomingwormboy

@wyomingwormboy

4 years

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@wyomingwormboy

3 years

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wyomingwormboy

@wyomingwormboy

2 years

#2022SDB #EvoDevo2022

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wyomingwormboy

@wyomingwormboy

5 months

As a grad student and postdoc, it felt like my job was to somehow carry a ball across the goal line, which was hard. As a PI, it’s sometimes felt like my job has been to carry a person carrying a ball across the goal line, which is much harder!

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wyomingwormboy

@wyomingwormboy

4 years

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wyomingwormboy

@wyomingwormboy

3 years

Scientific maturation: The transition from thinking that you don’t understand because the other person is much smarter than you, to thinking that you don’t understand because the other person didn’t explain it well and might very well be full of crap.

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wyomingwormboy

@wyomingwormboy

2 years

A shoutout to Postdocs: Some of us might reflect, “Those were the best years of my career. I wish I could go back!” But we mostly don’t mean it. Yes, focusing solely on science was nice. But the pay was lousy and the pressure unrelenting. I still have nightmares after >20 yrs.

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wyomingwormboy

@wyomingwormboy

4 years

Grant tips ( #3 ) When choosing between a review panel that is familiar with your work versus one that doesn’t know you as well, ask yourself “Do I want to be punched in the nads by a bunch of strangers or do I want to be stabbed in the back by people I thought were my friends?”

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wyomingwormboy

@wyomingwormboy

1 year

🥂 Here’s to scientists who have the grit to publish papers that aren’t sexy but do contain solid useful data. It’s not glamorous and the papers definitely don’t write themselves! But I’ve learned a lot of useful true things from reading such papers that have helped my research.

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wyomingwormboy

@wyomingwormboy

3 years

We do it because the further we get in our careers, the more the responsibilities get piled on. Real ones that feel like they matter. And we don’t want to let others down. And above all we want to do things well, for ourselves. And, yes, we even say “no” sometimes. 2/3

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wyomingwormboy

@wyomingwormboy

1 year

Today’s unsolicited advice to science trainees is simple. - Be a finisher.

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wyomingwormboy

@wyomingwormboy

3 years

I’m thinking that detecting new covid variants in the UK should be referred to as Strainspotting. Too early?

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wyomingwormboy

@wyomingwormboy

3 years

Damn.

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wyomingwormboy

@wyomingwormboy

1 year

When I Retire (an aspirational poem) When I retire I want colleagues to say: Why are you retiring? You’re still publishing papers! You’re still doing important service! You’re still teaching a key course! Yes. 1/6

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wyomingwormboy

@wyomingwormboy

3 years

Most of us aren’t extolling this way or telling others they should copy this lifestyle. We’re just being honest. And if we complain sometimes, that’s what humans do. And we still get out and do things, are involved and attentive parents, and even slack off sometimes. 3/3

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wyomingwormboy

@wyomingwormboy

4 years

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wyomingwormboy

@wyomingwormboy

2 years

I’m thinking of selling the lab’s irreproducible data as an NFT. Let the bidding start.

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wyomingwormboy

@wyomingwormboy

3 years

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wyomingwormboy

@wyomingwormboy

3 years

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wyomingwormboy

@wyomingwormboy

2 years

As a professor I envy Aaron Rogers today, as he will now have more time to dedicate to his research. 🔬

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wyomingwormboy

@wyomingwormboy

10 months

Excited to announce my divisive new country single “Try That in a Small Lab”.

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wyomingwormboy

@wyomingwormboy

2 months

#TAGC2024

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wyomingwormboy

@wyomingwormboy

3 years

Literally every goddam time I come in early to do an experiment over the weekend…

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wyomingwormboy

@wyomingwormboy

3 years

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wyomingwormboy

@wyomingwormboy

2 years

We write indecipherable script onto tubes with blunt sharpies using ink that rubs off just by looking at it. Then we put it in a warped box with no dividers, shake really hard, and let it build up a thick frost for years in a minus 20. Finally, we get mad when we can’t find it.

Arjun Raj

@arjunrajlab

2 years

What are everyone’s favorite ways to organize plasmids in lab? We use Benchling, but they don’t have a great list view so thinking about having a Google Sheet on the side.

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wyomingwormboy

@wyomingwormboy

3 years

Hope this appears as a thread. Final chapters at end!

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wyomingwormboy

@wyomingwormboy

1 year

Given stagnant funding levels, the justifiable need to increase trainee pay, and widespread difficulties in attracting qualified personnel, it’s hard to escape the conclusion that there are too many academic labs attempting to operate in the US. That includes me. And maybe you.

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wyomingwormboy

@wyomingwormboy

2 years

Heading to Ann Arbor to see my son. Also, having no shame, I invited myself to give a talk tomorrow! (Gyorgyi Csankovszki is very kind!) Do I list this on my CV as an Uninvited, Imposed, or Inflicted Seminar?

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wyomingwormboy

@wyomingwormboy

2 years

Some people in the lab apparently dressed up like me for Halloween. I totally missed it. I thought, finally these people are starting to dress in a sensible manner!

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wyomingwormboy

@wyomingwormboy

3 years

Someone must have come up with this already but… Is a Doodle poll for a Lab meeting called a Labradoodle?

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wyomingwormboy

@wyomingwormboy

3 years

This is getting personal… A good friend with stage IV breast cancer was just told that she can’t get into the hospital for surgery because they have their hands full with covid patients. All in favor of prioritizing vaccinated people needing critical care raise your hand. 🖐

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wyomingwormboy

@wyomingwormboy

4 years

A dear friend ( @DanStarrUCDavis ) just reminded me of a comprehensive, user-friendly, example-laden chapter I once published on statistics. As Dan succinctly puts it: “If this idiot can write it, you can understand it.” It’s even got bits of humor.

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wyomingwormboy

@wyomingwormboy

2 years

I’m happy to report that Wyoming is not experiencing a “postdoc crisis”. Because we’ve basically never relied on getting postdocs to begin with.

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wyomingwormboy

@wyomingwormboy

3 years

Do’s/Don’ts #7 ‣ Do understand the relative order of qualitative ‘confidence-expressing’ verbs and their true meanings. Demonstrates (damn sure) > Shows (pretty-damn sure) > Indicates (kinda sure) > Suggests (it might be true) > Implies (no idea really)

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wyomingwormboy

@wyomingwormboy

2 years

@geeky_jane @prashant87_ Scientists. We seriously need to STOP publishing in these predatory journals. Yes, most of us got indoctrinated drinking their stupid cool aid long ago, but we can wean ourselves. Stop sending them papers! And stop focusing on glam pubs during hiring, tenure, and grants. 🛑

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wyomingwormboy

@wyomingwormboy

3 years

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wyomingwormboy

@wyomingwormboy

3 years

The attending faculty look skeptical.

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wyomingwormboy

@wyomingwormboy

3 years

#1 /4 THE FAY LAB ANNOUNCES A HANDY NEW CRISPR DESIGN TOOL – CRISPRcruncher Takes any coding sequence and displays a comprehensive list of minimal substitutions that produce new restriction endonuclease sites while maintaining the original peptide sequence

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wyomingwormboy

@wyomingwormboy

4 years

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wyomingwormboy

@wyomingwormboy

3 years

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wyomingwormboy

@wyomingwormboy

3 years

Hey NIH. How about mandating vaccinations for laboratory workers who are paid off of NIH grants?

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wyomingwormboy

@wyomingwormboy

3 years

sunrise view from campsite earlier this week.

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wyomingwormboy

@wyomingwormboy

3 years

Seriously screw these vain billionaires who want to make space flight “more routine”. How about we make recycling, quality education, healthcare, and about 500 other things routine first.

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wyomingwormboy

@wyomingwormboy

4 years

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wyomingwormboy

@wyomingwormboy

3 years

Good God.

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wyomingwormboy

@wyomingwormboy

3 years

Grant reviews of famous books #1 The Three Musketeers. Success of the individual musketeers is overly dependent on the success of the other two musketeers. To Kill a Mockingbird. Missing detailed IACUC protocol for mockingbird euthanasia. Moby-Dick. Fishing expedition.

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wyomingwormboy

@wyomingwormboy

5 months

Science is not about normal-sized people standing on the shoulders of giants. It’s about normal-sized people standing on the shoulders of lots of other normal-sized people.

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wyomingwormboy

@wyomingwormboy

4 years

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wyomingwormboy

@wyomingwormboy

3 years

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wyomingwormboy

@wyomingwormboy

3 years

Who won’t be watching and doesn’t even know who’s playing in the Super Bowl today?

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wyomingwormboy

@wyomingwormboy

2 years

#2022SDB #EvoDevo2022

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wyomingwormboy

@wyomingwormboy

2 years

Undergrads may be on the verge of revolting…

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wyomingwormboy

@wyomingwormboy

8 months

Two paths diverged on a project. 🍂 And I took the one less fundable. 🙁 Which has totally screwed my career. 📉

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wyomingwormboy

@wyomingwormboy

2 years

Guide to Figures #4 More panels are always way more impressive. Consider breaking up figures as shown below. May require non-standard labels.

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wyomingwormboy

@wyomingwormboy

3 years

@florian_krammer I was thinking a medium shark.

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wyomingwormboy

@wyomingwormboy

2 years

@DrGuiton Ow. Everything you say is true. But administrators are lazy, and so rather than evaluating you professionally, they put it on the students. I’m not saying there’s no place for evals, and student input can be very useful, but it’s utility for judging pedagogy is very limited.

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wyomingwormboy

@wyomingwormboy

3 years

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wyomingwormboy

@wyomingwormboy

3 years

Tried this with my pubs. Apparently they’re likely to move the field backwards.

Nature Portfolio

@NaturePortfolio

3 years

A machine-learning model can be used to predict the future “impact” of research published in scientific literature, according to a @NatureBiotech paper. The model could aid in the construction of diversified, impact-optimized funding portfolios.

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wyomingwormboy

@wyomingwormboy

3 years

Breakfast cereals are mostly a tedious exercise in chewing and swallowing. Still I was unprepared for the utter joylessness of the bran flakes I encountered yesterday. The box should have contained a warning to alert those with a tendency towards melancholy.

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wyomingwormboy

@wyomingwormboy

11 months

I need to point out that the falcon probably wasn’t asked to review 10 grants & 5 papers or to serve on dozens of committees during her time of flight. She probably also wasn’t required to troubleshoot PCR or write an exhaustive response to reviewers. So…good for the damn falcon

Simon Kuestenmacher

@simongerman600

11 months

A female GPS-tracked falcon flew from South Africa to Finland. In 42 days she flew over 10,000 km. That's 230 km per day. What have you achieved in the last 42 days? Source:

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wyomingwormboy

@wyomingwormboy

1 year

Please check out Help! I’m a Scientist! And Retweet!

Help, I'm a Scientist!

A resource by scientists who've been in your shoes

helpimascientist.com

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wyomingwormboy

@wyomingwormboy

2 years

#2022SDB #EvoDevo2022

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wyomingwormboy

@wyomingwormboy

11 months

The Math. 100+ grants over 4 yrs. ~2 days per grant to read/write up. ~2 days of score revision and pre-meeting prep followed by 2-3 days for each of the 12 meetings. Add it up. It’s the same number of hours you’d work in a full time salaried position over the course of a year.

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wyomingwormboy

@wyomingwormboy

3 years

Can we agree that this is the worst ad for Patagonia clothing ever!

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wyomingwormboy

@wyomingwormboy

2 years

So, who else is sick of feeling like a deer in the headlights on Monday mornings where you mostly took the weekend off instead of using it to catch up on things you couldn’t get done the previous week?

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wyomingwormboy

@wyomingwormboy

3 years

Is it just me or do these images look ‘fabricated’?

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wyomingwormboy

@wyomingwormboy

2 years

Fridge freezer died over the weekend. Then started to heat up. Probably lost at least $20,000 in reagents.

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wyomingwormboy

@wyomingwormboy

1 year

Another failed colocalization experiment.

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wyomingwormboy

@wyomingwormboy

3 years

Just in time for #2021SDB

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@wyomingwormboy

3 years

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wyomingwormboy

@wyomingwormboy

2 years

Was wondering if there are any faculty who have specifically given a lecture on “how to give a talk”? I teach a grad level class (by Zoom) to about 25 students at Wyoming and was looking for someone to help me lead one of the upcoming classes. There would be some $ compensation.

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wyomingwormboy

@wyomingwormboy

2 years

OMFG NYU is spectacular! Wonderful setting, wonderful people, wonderful science! I just wish they had decent bagels here…

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wyomingwormboy

@wyomingwormboy

2 years

The Dept. of Molecular Biology at the University of Wyoming is seeking a new tenure-track Asst Prof in basically ANY relevant area! The job is mostly research with some teaching and service. And you can have coffee with me. And lunch. Sometimes dinner.

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wyomingwormboy

@wyomingwormboy

2 years

Guide to Figure Making #2 : It is literally impossible to make a scale bar that’s too big. Consider further emphasizing the bar with an inset panel.

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wyomingwormboy

@wyomingwormboy

2 years

Why academics shouldn’t write pop lyrics #1 : “A sizable number, though certainly not the entirety and perhaps not even an outright majority, of people were kung fu fighting.”

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wyomingwormboy

@wyomingwormboy

2 years

Does the C. elegans field have flaws? Sure, no scientific community is perfect. In our case it’s that we all love each other too goddamn much.

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wyomingwormboy

@wyomingwormboy

3 years

I hear the term “stakeholders” a lot and am wondering if these are people who assist at vampire killings? In any case, we’re supposed to listen to them.

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wyomingwormboy

@wyomingwormboy

1 year

My attempt to (gently touch) the third rail. ⚡️ Agree. Disagree. Send us your alternate take! 😬 Or use it as a spring board for an open honest discussion between trainees and their mentors.

Help I’m A Scientist

@hiascientist

1 year

Let’s talk about this… How hard should science trainees work? One perspective

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