Any evidence of a mutation in the virus?
Just watched
#outbreak
&
#contagion
so I know what I’m talking about, ok.
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@ryangraves
Look at
All viruses mutate frequently and rapidly as they pass from host to host. Can mutate into something less severe - or something more severe...
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@ryangraves
Yes.
..Positions nt28144 in ORF 8 and nt8782 in ORF1 are evolving. Samples out of China show they'd mutated 30.53% (29/95) and 29.47% (28/95), respectively. I'm currently figuring out why these are the ones mutating and how that would change the situation...
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Chloroquine is predicted to prevent orf1ab, ORF3a and ORF10 from attacking heme (red in red blood cells) and inhibit the binding of ORF8 to heme. Although 99% of the virus is seemingly stable, what's disturbing is ORF 1 and 8 are mutating the fastest...
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@ryangraves
No conclusive evidence as of now. But every virus carries L and S strain so reinfection is still a valid possibility.
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@GrahamRamsey
Hallo, please find the unroll here: Thread by
@davidasinclair
: Since my Harvard lab closed yesterday, I've been reading and interpreting this week's… . Talk to you soon. 🤖
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@ryangraves
It's a mad virus. It's not only attacking your lungs,it's attacking your ability to carry oxygen by attaching to heme. So yeah that insidiousness I'd say calls for mutations. It's not here to play.
#StayTheFHome
people.
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