Professor, Hematopathology,
@cbssm
, Director Path of Excellence in ethics, and clinical ethicist
@umichmedicine
. therapy dog owner/enthusiast. views are own.
Words from a Visitor:
"This is such a unique space that allowed me to quiet the noise and worldly concerns that I came here with. I feel lighter and my hope is restored."
The Rothko Chapel is open on Tuesday - Sunday from 10am - 6pm.
@laurenstricos
The obsession with in person routine meetings even occurs amongst antisocial pathologists. I don’t get it. I have no need to have large group meetings in the office in person ever again!
@Judah_Grunstein
Yeah let’s have more strained buttons on coats that barely cover the bum in our post-modern world. Lol. I fully enjoyed his thread and appreciate the lesson on classic dressing. Style has nothing to do with it.
Auer rods in a dysplastic neutrophil. A rare finding post-ATRA and in some M2 AMLs including t(8;21). This was AMML (M4 for the FAB folks out there).
#hemepath
#pathology
Every so often a bone marrow comes along that makes me happy I don’t only do lymph nodes. 65 year old woman with macrocytic anemia and thrombocytosis. What’s your dx?
#hemepath
#bonemarrow
So proud of
@HHamnvag
and our
@UMichPath
@umichmedicine
team. Alerted to new acute leukemia 8 am. Clinicians alerted of prelim at 9:30 am. Slide review signed out at 11 am. Flow completed 2 pm. Urgent FISH prelim done at 4:30 pm. What’s the dx? Thanks to the team who came in NYE!
How cool is it to make diagnoses every day on tissues such as this one? Pathologists have unique skills that are cultivated over many years. People ask how I recognize lymphomas. After many years, it’s as easy as seeing the faces of your friends.
#pathology
#hemepath
Nice case of primary amyloidosis in bone marrow. Thickened vessels with apple-green birefringence and 10 percent clonal plasma cells.
#pathology
#hematology
#hemepath
Pro tip: if you’re in the lung, stomach or lymph node, it’s not myeloma. It’s marginal zone lymphoma with plasmacytic differentiation.
#hemepath
#PathTwitter
Remember that “Hodgkin” type R-S cells have a prominent cherry red nucleolus which helps differentiate them from benign immunoblasts. CD30 can also mark immunoblasts so be careful.
#PathTwitter
#hemepath
This is CLL/SLL (see proliferation center in first image). These patients are at risk for herpes lymphadenitis. If the abnormal inclusions were not present, Kikuchi’s/lupus would be a good thought with the abrupt necrosis. Great job folks.
In case you’ve ever wondered about the origin of the name “pawn ball megakaryocytes,” the nuclear lobes are widely-spaced like the symbol.
#hemepath
#pathology
That was me (incognito) showing a bone marrow to a patient. I also did this in lymphoma clinic and patients love it. Would you want to see your biopsy?
#patholoy
#hemepath
#seeingpatients
It’s sad that so many people think efforts to promote social distancing are laziness or fear. To be clear, I’m not scared of getting this virus. I’m scared of giving it to you or your elderly parents. I’m scared to make rationing decisions.
#COVID19
Hi, I’m Lauren Smith. Hematopathologist and clinical ethicist. As an ethicist and daughter of cancer patients, I believe immediate release of results will cause immeasurable psychological harm
@Pathologists
#capchat
@UMichPath
I’ve been reflecting a lot on what our move offsite did to morale and overall faculty happiness. We moved to a bldg 2-3 mikes from the hospital 5 yrs ago in 2018.
#PathTwitter
#MedTwitter
@drninashapiro
Yesterday I heard a deli counter worker at a fancy food market in Ann Arbor tell someone that a study just came out showing vaccine causes cancer in kids. I told him he was wrong and he argued that i hadn’t seen it since it just came out. Prob in the J of consp thr.
Calling all new
#meded
#pathology
trainees. I wish you the best and I hope I can convince you to pursue
#hemepath
once you’ve started. Congratulations on your excellent career choice. Pathology is the bomb.
This guy passed his first test to become a certified therapy dog! Coming to a retirement home/hospital or undergrad event
@UMich
@umichmedicine
soon!
#therapaws
This is an example of leukemic phase of follicular lymphoma. The clefts (pale lines) through the nucleus and lack of cytoplasm are highly characteristic. CLL may look bilobed and have wider indentations. ALL is in the differential but chromatin usually smoother.
"Is there a doctor on the plane?"
This JAMA article has printable cards that can remind you what to do in a medical emergency on an airplane.
In-Flight Medical Emergencies: A Review
@VioletaYammine
Beautiful immunoblastic DLBCL. Ddx includes plasmablastic lymphoma, ALK + LBCL and PEL. PBL should be CD138 + and CD20 neg (75% EBER). PEL HHV8 +. ALK + usually neg for B-cell markers but may express plasma cell markers and always ALK (usually granular golgi).
#hemepath
Whenever I see immunoblastic morphology I have the same ddx:
1) Immunoblastic DLBCL 2) plasmablastic lymphoma/Anaplastic plasmacytoma 3) PEL (solid variant) 4) ALK pos DLBCL. This guides ipox w/u. What should I do next?
@soumya_goblue
And it is pretty offensive to say that we chose our specialty for work life balance. We have someone on call 24/7 so it sounds like a communication problem to me. Or maybe you don’t really need negative path to discharge.
Body fluid on patient with pb lymphocytosis consisting of T-cells expressing normal intensity CD3, CD4, CD5, and CD7. What is your diagnosis?
#hemepath
#pathology
PSA: if you see amyloid in the head/neck or other tissue sites like lung, it’s probably a MALT lymphoma with extensive plasmacytic diff (not systemic amyloidosis). It may have few B cells or small clusters.
#PathTwitter
An absolute lymphocytosis in a patient over 50 is a lymphoproliferstive disorder until proven otherwise. Public service announcement.
#hemepath
#hematology
#pathology
My dad died of GI bleed 12/18/19 after treatment for CMML. I hoped for a better 2020. Now I just hope that
#SocialDistancing
saves your elderly relatives. I will do everything I can to
#FlattenTheCurve
for your loved ones. That is my moral duty.
Beautiful CHL with pleomorphic cells. CD30, CD15 and PAX-5 shown. My wonderful mentor Dr. Bertram Schnitzer told me that CHL can have very pleomorphic cells.
#mentor
#hemepath
#hodgkins
If you are planning on applying to
@UMichPath
#hemepath
fellowship (but have not yet) and you have your heart set on coming to Ann Arbor, please DM me since the process gets earlier every year.
#PathTwitter