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Lauren Smith, MD, HEC-C Profile
Lauren Smith, MD, HEC-C

@lbsmithmd

3,061
Followers
365
Following
639
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4,527
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Professor, Hematopathology, @cbssm , Director Path of Excellence in ethics, and clinical ethicist @umichmedicine . therapy dog owner/enthusiast. views are own.

Ann Arbor, MI
Joined November 2016
Don't wanna be here? Send us removal request.
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@lbsmithmd
Lauren Smith, MD, HEC-C
1 year
My honors thesis @UMich was on the amazing #rothko chapel in 1992. It’s a phenomenal space if you ever have a chance to visit Houston.
@rothkochapel
Rothko Chapel
2 years
Words from a Visitor: "This is such a unique space that allowed me to quiet the noise and worldly concerns that I came here with. I feel lighter and my hope is restored." The Rothko Chapel is open on Tuesday - Sunday from 10am - 6pm.
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Lauren Smith, MD, HEC-C
2 years
@laurenstricos The obsession with in person routine meetings even occurs amongst antisocial pathologists. I don’t get it. I have no need to have large group meetings in the office in person ever again!
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@lbsmithmd
Lauren Smith, MD, HEC-C
2 years
What is this cell and when is it seen? #hemepath #MedTwitter #heme
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Lauren Smith, MD, HEC-C
4 years
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Lauren Smith, MD, HEC-C
10 months
@Judah_Grunstein Yeah let’s have more strained buttons on coats that barely cover the bum in our post-modern world. Lol. I fully enjoyed his thread and appreciate the lesson on classic dressing. Style has nothing to do with it.
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Lauren Smith, MD, HEC-C
4 years
Morphologic diagnosis please? Look carefully #hemepath #pathology
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@lbsmithmd
Lauren Smith, MD, HEC-C
3 years
Auer rods in a dysplastic neutrophil. A rare finding post-ATRA and in some M2 AMLs including t(8;21). This was AMML (M4 for the FAB folks out there). #hemepath #pathology
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@lbsmithmd
Lauren Smith, MD, HEC-C
4 years
Beautiful example of a classic in #pathology #hemepath What is this?
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@lbsmithmd
Lauren Smith, MD, HEC-C
3 years
Small intestine mass. What’s your ddx on H&E? #pathology #hemepath
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@lbsmithmd
Lauren Smith, MD, HEC-C
3 years
Child with fatigue and normal platelet count. What is your diagnosis? #pitallsinheme #PathTwitter
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@lbsmithmd
Lauren Smith, MD, HEC-C
2 years
What kind of #lymphoma is this? No need to magnify. #pathology #MedTwitter
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@lbsmithmd
Lauren Smith, MD, HEC-C
3 years
World’s biggest multinucleated giant cell #Pathtwitter #hemepath
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@lbsmithmd
Lauren Smith, MD, HEC-C
3 years
Follicular hyperplasia and beautiful monocytoid B-cells after #Covid_19 vaccine. #hematology #hemepath #pathology
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@lbsmithmd
Lauren Smith, MD, HEC-C
4 years
18 year old with cervical lymphadenopathy. What is your diagnosis? #pathology #hemepath
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@lbsmithmd
Lauren Smith, MD, HEC-C
3 years
My advice to #pathology junior faculty members: take all of your vacation days. That’s the tweet.
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@lbsmithmd
Lauren Smith, MD, HEC-C
5 years
Every so often a bone marrow comes along that makes me happy I don’t only do lymph nodes. 65 year old woman with macrocytic anemia and thrombocytosis. What’s your dx? #hemepath #bonemarrow
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@lbsmithmd
Lauren Smith, MD, HEC-C
1 year
What is the diagnosis? Notice anything unusual? #PathTwitter #MedTwitter #heme
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@lbsmithmd
Lauren Smith, MD, HEC-C
4 years
Young person with enlarged cervical LN. what immunostains would you order? #pathology #VirtualPath #hemepath
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@lbsmithmd
Lauren Smith, MD, HEC-C
4 months
So proud of @HHamnvag and our @UMichPath @umichmedicine team. Alerted to new acute leukemia 8 am. Clinicians alerted of prelim at 9:30 am. Slide review signed out at 11 am. Flow completed 2 pm. Urgent FISH prelim done at 4:30 pm. What’s the dx? Thanks to the team who came in NYE!
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Lauren Smith, MD, HEC-C
4 years
What are the 2 diagnoses shown here in this lymph node? #hemepath #pathology #noimmunostains
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@lbsmithmd
Lauren Smith, MD, HEC-C
1 year
Pre-order our practical new lymph node biopsy book @TheUSCAP . A labor of love by me, Anamarija Perry @UMichPath , and Becky King @MayoClinicPath #PathTwitter #MedTwitter
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Lauren Smith, MD, HEC-C
1 year
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Lauren Smith, MD, HEC-C
1 year
Amazing gift from my former fellow Vivian Hathuc #MedTwitter #Pathtwitter ❤️❤️❤️❤️❤️❤️❤️
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@lbsmithmd
Lauren Smith, MD, HEC-C
3 years
Small intestine 60-year-old man. What’s your differential? #pathology #Gastroenterology #hemepath #oncology
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@lbsmithmd
Lauren Smith, MD, HEC-C
1 year
What cytogenetic abnormality are you suspecting? Why? #PathTwitter #medtwitter #leukemia
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@lbsmithmd
Lauren Smith, MD, HEC-C
4 years
How cool is it to make diagnoses every day on tissues such as this one? Pathologists have unique skills that are cultivated over many years. People ask how I recognize lymphomas. After many years, it’s as easy as seeing the faces of your friends. #pathology #hemepath
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Lauren Smith, MD, HEC-C
3 years
Cells that read the textbook. What’s the clinical presentation? #hemepath #pathology #hematology
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Lauren Smith, MD, HEC-C
3 years
Nice case of primary amyloidosis in bone marrow. Thickened vessels with apple-green birefringence and 10 percent clonal plasma cells. #pathology #hematology #hemepath
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Lauren Smith, MD, HEC-C
10 months
My #hemepath @Barbie seems especially timely now. Thanks to Dr. Vivian Hathuc for predicting all the cool trends. #MedTwitter #PathTwitter
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Lauren Smith, MD, HEC-C
4 years
Elderly man with buccal ulcer extending to mandible. CD20 and CD30 shown. What would you do next? #pathology #hemepath
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Lauren Smith, MD, HEC-C
4 years
What is the diagnosis? Immunostain is cyclin D1 #pathology #hemepath #VirtualPath
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@lbsmithmd
Lauren Smith, MD, HEC-C
4 years
Young woman with persistent rash. What is your diagnosis? #hemepath #pathology #dermpath
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@lbsmithmd
Lauren Smith, MD, HEC-C
6 months
70 year old man with history of lymphoma. What kind of lymphoma does he have? #MedTwitter #PathTwitter #heme
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Lauren Smith, MD, HEC-C
6 months
Cluster of cells in the CSF. Is this hematopoietic? Why or why not? #MedTwitter #PathTwitter #cytology #heme
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Lauren Smith, MD, HEC-C
2 years
Congrats to our new trainees! @UMichPath #PathMatch22
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Lauren Smith, MD, HEC-C
4 years
Young person (30s) with mediastinal mass. Impending SVC syndrome. What’s your differential and most likely dx? #hemepath #pathology What immunostains?
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@lbsmithmd
Lauren Smith, MD, HEC-C
4 years
Young woman with fever and renal failure. What is your diagnosis? #pathology #hemepath #bestcaseever
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@lbsmithmd
Lauren Smith, MD, HEC-C
1 year
Pro tip: if you’re in the lung, stomach or lymph node, it’s not myeloma. It’s marginal zone lymphoma with plasmacytic differentiation. #hemepath #PathTwitter
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@lbsmithmd
Lauren Smith, MD, HEC-C
5 years
What is the relevant history here? #pathology #hemepath #microbiology
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Lauren Smith, MD, HEC-C
4 years
Amazing case similar to one @DennisOMalleyMD shared with me recently. What do you think is in the plasma cells? #hemepath #pathology
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Lauren Smith, MD, HEC-C
3 years
Remember that “Hodgkin” type R-S cells have a prominent cherry red nucleolus which helps differentiate them from benign immunoblasts. CD30 can also mark immunoblasts so be careful. #PathTwitter #hemepath
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Lauren Smith, MD, HEC-C
4 years
Cool classic Hodgkin #lymphoma mimicking cat scratch or necrotizing granulomas. A well-known pattern of nodular sclerosis type. CD30 and CD15 pictured. #pathology #hemepath
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@lbsmithmd
Lauren Smith, MD, HEC-C
1 year
30-year-old woman with a mediastinal mass and SVC syndrome. What is your leading ddx? #PathTwitter #hemepath #MedTwitter
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@lbsmithmd
Lauren Smith, MD, HEC-C
4 years
Always remember that starry sky isn’t always #burkitt #lymphoma . Often it’s lymphoblastic lymphoma. #hemepath #pathology
@NehGuptaaMD
Neha Gupta
4 years
Mesenteric mass. Dx? (we had a wonderful lecture by Dr. Medeiros today 6/30) #hemepath
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Lauren Smith, MD, HEC-C
4 years
Woman with gingival mass. CD4 shown. What stains would you order? #pitfalls #entpath #headandneckpath #hemepath #oralpath
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Lauren Smith, MD, HEC-C
4 years
Not the best H/Es (sorry). But classic morphologic features. What is your diagnosis? #virtualpath #hemepath #pathology
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@lbsmithmd
Lauren Smith, MD, HEC-C
10 months
It’s finally out! Excited about my collaboration with these wonderful women. #PathTwitter #MedTwitter #lymphoma #heme @Wolters_Kluwer @MayoClinicPath @mayocliniclabs @UMichPath
@lbsmithmd
Lauren Smith, MD, HEC-C
1 year
Pre-order our practical new lymph node biopsy book @TheUSCAP . A labor of love by me, Anamarija Perry @UMichPath , and Becky King @MayoClinicPath #PathTwitter #MedTwitter
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Lauren Smith, MD, HEC-C
4 years
Supraclavicular lymph node. What is the differential diagnosis? #pathology #hemepath
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Lauren Smith, MD, HEC-C
3 years
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@lbsmithmd
Lauren Smith, MD, HEC-C
4 years
This is CLL/SLL (see proliferation center in first image). These patients are at risk for herpes lymphadenitis. If the abnormal inclusions were not present, Kikuchi’s/lupus would be a good thought with the abrupt necrosis. Great job folks.
@lbsmithmd
Lauren Smith, MD, HEC-C
4 years
What are the 2 diagnoses shown here in this lymph node? #hemepath #pathology #noimmunostains
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Lauren Smith, MD, HEC-C
4 years
Beautiful micromegakaryocyte and abnormal platelets. When do you see micromegs? #hemepath #pathology
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@lbsmithmd
Lauren Smith, MD, HEC-C
3 years
@UrbaneDoc4Kids @tnicholsmd @TheAtlantic Yeah I made a positive comment about masks on his post and now all the gd anti-vax/maskers are out to get me. Bring it on.
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Lauren Smith, MD, HEC-C
4 years
In case you’ve ever wondered about the origin of the name “pawn ball megakaryocytes,” the nuclear lobes are widely-spaced like the symbol. #hemepath #pathology
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@lbsmithmd
Lauren Smith, MD, HEC-C
5 years
That was me (incognito) showing a bone marrow to a patient. I also did this in lymphoma clinic and patients love it. Would you want to see your biopsy? #patholoy #hemepath #seeingpatients
@UMichPath
Michigan Pathology
5 years
Pathologists at #USCAP2019 : We're curious to hear how you feel about patient-pathologist consultation programs. Would you be willing to fill out this 1-minute survey? #visiblepathologist #patientcenteredpathology
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Lauren Smith, MD, HEC-C
3 years
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Lauren Smith, MD, HEC-C
6 months
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Lauren Smith, MD, HEC-C
4 years
It’s sad that so many people think efforts to promote social distancing are laziness or fear. To be clear, I’m not scared of getting this virus. I’m scared of giving it to you or your elderly parents. I’m scared to make rationing decisions. #COVID19
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@lbsmithmd
Lauren Smith, MD, HEC-C
3 years
Hi, I’m Lauren Smith. Hematopathologist and clinical ethicist. As an ethicist and daughter of cancer patients, I believe immediate release of results will cause immeasurable psychological harm @Pathologists #capchat @UMichPath
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@lbsmithmd
Lauren Smith, MD, HEC-C
3 years
@DGlaucomflecken My pug Lyle loved the squeaky parts
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Lauren Smith, MD, HEC-C
3 years
To all of the #hematology #oncology trainees out there, please know that #flowcytomery is not indicated in patients with neutrophilia or isolated anemia. It is a test designed to immunophenotype blasts and lymphoma cells. #trusttheautodiff #publicserviceannouncement
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@lbsmithmd
Lauren Smith, MD, HEC-C
2 years
Elderly person with enlarged lymph node. Differential dx please! #hemepath #MedTwitter
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Lauren Smith, MD, HEC-C
2 years
Soft tissue mass in middle-aged person. What is your ddx? What immunostains would you like? #hemepath #medtwitter
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@lbsmithmd
Lauren Smith, MD, HEC-C
3 years
Fall in MI
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Lauren Smith, MD, HEC-C
1 year
I’ve been reflecting a lot on what our move offsite did to morale and overall faculty happiness. We moved to a bldg 2-3 mikes from the hospital 5 yrs ago in 2018. #PathTwitter #MedTwitter
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@lbsmithmd
Lauren Smith, MD, HEC-C
2 years
@drninashapiro Yesterday I heard a deli counter worker at a fancy food market in Ann Arbor tell someone that a study just came out showing vaccine causes cancer in kids. I told him he was wrong and he argued that i hadn’t seen it since it just came out. Prob in the J of consp thr.
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Lauren Smith, MD, HEC-C
6 months
Our @UMichPath case. Remember that ATLL can mimic lots of things including T lymphoblastic leukemia #PathTwitter #SH2023
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Lauren Smith, MD, HEC-C
3 years
Frontal bone. What immunostains would you order? #pathology
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@lbsmithmd
Lauren Smith, MD, HEC-C
4 months
Pleural fluid of patient with lung mass. What’s your dx? #PathTwitter #MedTwitter
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@lbsmithmd
Lauren Smith, MD, HEC-C
5 years
@UMichPath Photos by Dustin
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@lbsmithmd
Lauren Smith, MD, HEC-C
2 years
First art show in the books
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@lbsmithmd
Lauren Smith, MD, HEC-C
4 years
Calling all new #meded #pathology trainees. I wish you the best and I hope I can convince you to pursue #hemepath once you’ve started. Congratulations on your excellent career choice. Pathology is the bomb.
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@lbsmithmd
Lauren Smith, MD, HEC-C
4 months
This guy passed his first test to become a certified therapy dog! Coming to a retirement home/hospital or undergrad event @UMich @umichmedicine soon! #therapaws
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@lbsmithmd
Lauren Smith, MD, HEC-C
4 years
This is an example of leukemic phase of follicular lymphoma. The clefts (pale lines) through the nucleus and lack of cytoplasm are highly characteristic. CLL may look bilobed and have wider indentations. ALL is in the differential but chromatin usually smoother.
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@lbsmithmd
Lauren Smith, MD, HEC-C
3 years
I’ve been that person more than once and as a pathologist, I need these.
@CatchTheBaby
Ruth Ann Crystal, MD
3 years
"Is there a doctor on the plane?" This JAMA article has printable cards that can remind you what to do in a medical emergency on an airplane. In-Flight Medical Emergencies: A Review @VioletaYammine
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Lauren Smith, MD, HEC-C
2 years
I never believed that “sinus histiocytosis” in a report could be misinterpreted as Rosai-Dorfman disease until today.
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Lauren Smith, MD, HEC-C
3 years
(Re)learning things in my new volunteer job as a hospital #autopsy attending. Subtle contraction band necrosis in the myocardium after myocardial infarction. #cardiac #pathology #nolymphomahereguys
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@lbsmithmd
Lauren Smith, MD, HEC-C
4 years
Beautiful immunoblastic DLBCL. Ddx includes plasmablastic lymphoma, ALK + LBCL and PEL. PBL should be CD138 + and CD20 neg (75% EBER). PEL HHV8 +. ALK + usually neg for B-cell markers but may express plasma cell markers and always ALK (usually granular golgi). #hemepath
@okja2024
Usuario
4 years
Axillary node 68 px. CD20+ (pic), BCL2 +, CD3/CD5/MUM1/CD138/BCL6/CD10/EBER neg Ki67 50% #HemePath #lymphoma #pathology #pathologist
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Lauren Smith, MD, HEC-C
3 years
@VPrasadMDMPH Kids are fine with masks. It’s the adults who don’t think kids are fine. It’s a pandemic.
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Lauren Smith, MD, HEC-C
1 year
@choo_ek As an introverted woman who hates phone calls, I always find it fascinating that a man would ever talk that much.
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@lbsmithmd
Lauren Smith, MD, HEC-C
5 years
Currently recruiting a Hematopathologist and #hemepath fellowship director @UMichPath ! See ads on @Pathoutlines and @SocforHemepath for additional details. Apply to work with our dream team!
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Lauren Smith, MD, HEC-C
3 years
Whenever I see immunoblastic morphology I have the same ddx: 1) Immunoblastic DLBCL 2) plasmablastic lymphoma/Anaplastic plasmacytoma 3) PEL (solid variant) 4) ALK pos DLBCL. This guides ipox w/u. What should I do next?
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Lauren Smith, MD, HEC-C
2 years
@soumya_goblue And it is pretty offensive to say that we chose our specialty for work life balance. We have someone on call 24/7 so it sounds like a communication problem to me. Or maybe you don’t really need negative path to discharge.
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@lbsmithmd
Lauren Smith, MD, HEC-C
4 years
Body fluid on patient with pb lymphocytosis consisting of T-cells expressing normal intensity CD3, CD4, CD5, and CD7. What is your diagnosis? #hemepath #pathology
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@lbsmithmd
Lauren Smith, MD, HEC-C
3 years
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Lauren Smith, MD, HEC-C
1 year
Obligatory on my way to @TheUSCAP selfie #nola
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@lbsmithmd
Lauren Smith, MD, HEC-C
5 years
Yes—many MALT lymphomas are IGG4 positive. Don’t make the mistake of calling it IGG4-related disease!
@javidiparsijani
Sara Javidiparsijani, MD, FCAP
5 years
Interesting case of MALT lymphoma (conjunctiva) that is also IgG4(+)...
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Lauren Smith, MD, HEC-C
3 years
PSA: if you see amyloid in the head/neck or other tissue sites like lung, it’s probably a MALT lymphoma with extensive plasmacytic diff (not systemic amyloidosis). It may have few B cells or small clusters. #PathTwitter
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@lbsmithmd
Lauren Smith, MD, HEC-C
2 years
I was so honored to be a visiting professor @CLEClinicLabs hosted by @DrMNichols and @monakashim1 Thank you so much for a wonderful visit.
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@lbsmithmd
Lauren Smith, MD, HEC-C
3 years
An absolute lymphocytosis in a patient over 50 is a lymphoproliferstive disorder until proven otherwise. Public service announcement. #hemepath #hematology #pathology
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Lauren Smith, MD, HEC-C
1 year
Possibly the nicest thank you note I’ve ever received. #payitforward #randomactsofkindness
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Lauren Smith, MD, HEC-C
3 years
Happy New Year to everyone on Twitter who has made this solitary year more bearable. Thank you #pathology and #ethics and all other friends.
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@lbsmithmd
Lauren Smith, MD, HEC-C
4 years
My dad died of GI bleed 12/18/19 after treatment for CMML. I hoped for a better 2020. Now I just hope that #SocialDistancing saves your elderly relatives. I will do everything I can to #FlattenTheCurve for your loved ones. That is my moral duty.
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@lbsmithmd
Lauren Smith, MD, HEC-C
4 years
Come to our @TheUSCAP short course on Wednesday 8-12 featuring the amazing Anamarija Perry and the always entertaining Adam Bagg #USCAP2020 #hemepath #pathology
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@lbsmithmd
Lauren Smith, MD, HEC-C
2 years
Organ and diagnosis? See- #hemepath doesn’t always need #ipox #Medtwitter
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@lbsmithmd
Lauren Smith, MD, HEC-C
5 years
Beautiful CHL with pleomorphic cells. CD30, CD15 and PAX-5 shown. My wonderful mentor Dr. Bertram Schnitzer told me that CHL can have very pleomorphic cells. #mentor #hemepath #hodgkins
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Lauren Smith, MD, HEC-C
4 years
Three Laurens signing out #hemepath @UMichPath
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@lbsmithmd
Lauren Smith, MD, HEC-C
2 years
@DGlaucomflecken But do they know the history behind Congo Red???
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Lauren Smith, MD, HEC-C
1 year
The incomparable Dr. Rob McKenna #hemepathgiants #PathTwitter #USCAP2023
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@lbsmithmd
Lauren Smith, MD, HEC-C
2 years
Turquoise lake near Leadville and Camp Hale #Colorado
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Lauren Smith, MD, HEC-C
4 years
Interesting AITL that mimicked Hodgkin on H/E. ICOS and CD21 shown.
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@lbsmithmd
Lauren Smith, MD, HEC-C
3 years
If you are planning on applying to @UMichPath #hemepath fellowship (but have not yet) and you have your heart set on coming to Ann Arbor, please DM me since the process gets earlier every year. #PathTwitter
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