Kara Bernstein @kara_bernstein Twitter profile

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Kara Bernstein

@kara_bernstein

3 months

Nothing is more beautiful than U. Penn’s campus in the spring.

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Kara Bernstein

@kara_bernstein

4 months

Checkout our new preprint on the human Shu complex and how it promotes RAD51 by modulating RPA dynamics on ssDNA.

The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA

Templated DNA repair that occurs during homologous recombination and replication stress relies on RAD51. RAD51 activity is positively regulated by BRCA2 and the RAD51 paralogs. The Shu complex is a...

www.biorxiv.org

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Kara Bernstein

@kara_bernstein

3 months

Thrilled to present our new studies on the Shu complex and how it finds replication damage at the Gordon Research Conference in Ventura, CA. Jeremy Stark @jstarklab and Shan Zha @zha_lab organized an incredible meeting!

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Kara Bernstein

@kara_bernstein

2 months

Went to a lecture on campus about the origins of Hatikvah and stumbled into Benjamin Franklin’s desk! You never know what you will find at Penn. So cool!

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Kara Bernstein

@kara_bernstein

3 months

You think you know where a protein starts! We show that RAD51C has two start sites and this has important implications for cancer patients with variant in the first methionine.

Variants in the first methionine of RAD51C are homologous recombination proficient due to an...

In the 20+ years since the discovery of RAD51C, scientists have been perplexed as to how missense variants in this tumor suppressor gene impacts its function and pathogenicity. With a strong connec...

pubmed.ncbi.nlm.nih.gov

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Kara Bernstein

@kara_bernstein

3 months

Dr. Ruth Gottesman, a retired professor from Albert Einstein School of Medicine, donated $1 billion to Einstein so that medical school students would be debt free and to help diversify the student body. It’s an inspiring story. #inspiringwomen