THE "CITIZEN CANE".....
......OF MICROSCOPY
I'm teaching 1st-year grad students about cell migration tomorrow. This is the first movie they will see. An immune cell hunting down a bacterium among red blood cells. Movie credit: David Rogers.
#CellBiology
The Citizen Kane
of Microscopy
An immune cell (neutrophil) hunting down a bacterium among red blood cells. Filmed through a microscope by David Rogers.
#CellBiology
#Microscopy
Just a normal cell going through cell division…… Wait!!! What???!!! It was not so normal after all! I guess we have to study membrane blebs now…. The data said so.
NEURONAL GROWTH CONES
I spent years studying these little critters and I still do not understand them. Such is the burden that comes with choosing not to be a reductionist. Upside? Cells surprise me all the time. That has kept me coming back for 20 years.
#CellBiology
NEURONAL GROWTH CONES
I spent years studying these little critters and I still do not understand them. Such is the burden that comes with choosing not to be a reductionist. Upside? Cells surprise me all the time. That has kept me coming back for 20 years.
#CellBiology
Cell 1: “I like going right.”
Cell 2: “I like going left.”
Cell 1: “I think I will go right forever.”
Cell 2: “Nope. You’re coming with me.”
Cell 1: “Where are we going?”
Cell 2: “No idea but at least we’ll be together.”
A cancer cell videoed through a microscope. It has three nuclei (blue). The mitochondria (yellow) and a cytoskeletal component (VASP;red) are also shown.
#CellBiology
#microscopy
#SciArt
FULL OF ENERGY
Mitochondria (purple) create much of the chemical energy for the cell. And when compared to the slow moving nucleus (green), mitochondria seem hyperactive. Full of energy indeed.
#MitoMonday
#CellBiology
The powerhouses of our cells, mitochondria, moving around the nucleus. It reminds me of a toddler interacting with a patient golden retriever.
#CellBiology
#microscopy
This is the first video of cell division captured in the Burnette lab. The DNA--starting in condensed chromosomes--and DIC are shown. Little did we know then that we would become obsessed with membrane blebs; apparent in this video during cytokinesis.
#CellBiology
#microscopy
Happy Valentine's Day!
Here is a single heart muscle cell (cardiac myocyte)--which itself is shaped like a little heart--as seen through a microscope.
#cardiotwitter
#CellBiology
#SciArt
This is a single cell as seen through a microscope. It shows the movement of mitochondria (green), microtubules (red) and actin filaments (blue).
#CellBiology
#Microscopy
The Citizen Kane of Cell Division
Walther Flemming published this time-lapse of a dividing cell in 1882. He drew the data by hand while looking in his microscope.
#CellBiology
#microscopy
#SciArt
This movie shows the powerhouses of the cell, mitochondria, and DNA within a single cancer cell with three nuclei as seen through a microscope.
#CellBiology
#Microscopy
This is a single epithelial cell as seen through a microscope. The nucleus (blue), mitochondria (yellow) and the actin filament cytoskeleton (magenta) are shown.
#CellBiology
#microscopy
The "Citizen Kane" of Microscopy
I am teaching first-year graduate students about cell motility tomorrow. This is the first movie they will see; a classic recording by David Rogers of a neutrophil chasing down a bacterium.
#CellBiology
#Microscopy
Three cells going through cell division videoed through a microscope. Left to right: Control, Myosin IIA depletion, and Myosin IIB depletion. This data screamed, "Study membrane blebs!" So we did....
#CellBiology
#Biology
#Science
THE CELL’S POWERHOUSE
Mitochondria (yellow) make much of the chemical energy that fuels the life of a cell. They also move rapidly as seen in this cancer cell compared to the relatively slow moving nucleus (blue) and cellular adhesions (purple).
#MitoMonday
#CellBiology
A single heart muscle cell (cardiac myocyte) videoed through the microscope. The spaghetti looking organelles are the powerhouses of the cell, mitochondria. Those white dots? You tell me...
#CellBiology
#cardiotwitter
#microscopy
THE CELL’S POWERHOUSE
Mitochondria (yellow) make much of the chemical energy that fuels the life of a cell. They also move rapidly as seen in this cancer cell compared to the relatively slow moving nucleus (blue) and cellular adhesions (purple).
#MitoMonday
#CellBiology
FULL OF ENERGY
Mitochondria (purple) create much of the chemical energy for the cell. And when compared to the slow moving nucleus (green), mitochondria seem hyperactive. Full of energy indeed.
#MitoMonday
#CellBiology
A cell videoed through a microscope. DNA in the nucleus (green) and the powerhouses/overlords of the cell, mitochondria (purple), are shown. If your biology teacher taught you that mitochondria look like little beans, you now know better.
#Science
#Biology
#CellBiology
#Art
THE "CITIZEN CANE".....
......OF MICROSCOPY
An immune cell hunting down a bacterium among red blood cells. A picture may be worth a thousand words, but a movie can contain exponential insights.
Movie credit: David Rogers (
@VanderbiltU
, 1950's).
@VUBasicSciences
POWERHOUSE AND HARD DRIVE
Watching the powerhouse of the cell - mitochondria (yellow) - can be as mesmerizing as watching a camp fire. DNA (blue) is not as fun at this timescale. Luckily there are people who can image DNA better than me.
#MitoMonday
#CellBiology
The Citizen Kane of Cell Division
Walther Flemming published this time-lapse of a dividing cell in 1882. He drew the data by hand while looking in his microscope.
#CellBiology
#microscopy
#SciArt
The powerhouses/overlords of the cell, mitochondria (yellow), and DNA in the nucleus (blue) videoed through a microscope.
#CellBiology
#microscopy
#SciArt
POWERHOUSE AND HARD DRIVE
Watching the powerhouse of the cell - mitochondria (yellow) - can be as mesmerizing as watching a camp fire. DNA is blue.
#CellBiology
The powerhouse of our cells, mitochondria (green), and the genetic information in our cells, DNA (purple), videoed in a cancer cell with three nuclei using a microscope.
#CellBiology
#microscopy
Neuronal growth cones as seen through a microscope. Movie shows a time lapse of the extensions from a cultured bag cell neuron isolated from Aplysia californica (i.e., a giant sea slug).
#CellBiology
#microscopy
A cell videoed through a microscope. DNA in the nucleus and the powerhouses/overlords of the cell, mitochondria, are shown.
#Science
#Nature
#CellBiology
#Art
A cell videoed through a microscope. DNA in the nucleus (blue), mitochondria (yellow), and the cytoskeletal protein VASP (purple) are shown.
#CellBiology
#microscopy
#SciArt
Movie of mitochondria (green), DNA (blue) and actin (red) in an epithelial cell acquired with a spinning disk confocal microscope.
#MitoMonday
#CellBiology
Neuronal growth cones integrating information from their environment.
1- “Hey ya’ll. Are we on glass.”
2- “Yup”
3- “Yup”
4- “Yup”
1- :-/
A
#CellBiology
story.
A crawling cancer cell as seen through a microscope. The nucleus (yellow), Golgi apparatus (blue) and actin cytoskeleton (red) are shown.
#CellBiology
#Microscopy
#Melanoma
DNA (green) and mitochondria videoed in a single cancer cell using a microscope. Mitochondria play multiple roles inside of a cell (e.g., powerplant, judge, and executioner); all while impersonating worms at a dance party.
#CellBiology
#microscopy
#SciArt
POWERHOUSE AND HARD DRIVE
Watching the powerhouse of the cell - mitochondria (yellow) - can be as mesmerizing as watching a camp fire. DNA (blue) is not as fun at this timescale. Luckily there are people who can image DNA better than I can.
#MitoMonday
#CellBiology
A cell videoed through a microscope. DNA in the nucleus (red) the powerhouses/overlords of the cell, mitochondria (cyan), and actin filaments (gray) are shown.
#Science
#Biology
#CellBiology
#Art
The powerhouses of our cells, mitochondria, are not all bean-shaped as your high school text book would you have you believe. As soon as you define their shape, they change it. Mitochondria are not into labels.
#MitoMonday
#CellBiology
#Microscopy
Dying melanoma cancer cells videoed through a microscope. I find the moment when they finally "pop" quite satisfying. Notice the "apoptotic bodies" that were released from the cells scattered around the dish.
#ScienceTermOfTheWeek
.
#Science
#Biology
#CellBiology
#Art
A cancer cell as seen through a microscope. The three nuclei in this cell (blue), mitochondria (yellow) and the cytoskeleton (red) are shown.
#CellBiology
Should a cell have three nuclei? No.
Explanations
#NSGC20
? Genomic instability? Cytokinesis failure?
The is a single cell as seen through a microscope. Actin filaments (purple), mitochondria (blue) the nucleus (orange) are shown. The excitation light caused phototoxicity. Does anyone know how I figure that out?
#CellBiology
#Microscopy
#SciArt
A cell videoed through a microscope. DNA in the nucleus (blue), the powerhouses/overlords of the cell, mitochondria (yellow), and actin filaments (purple) are shown.
#Science
#Biology
#CellBiology
#Art
The powerhouses/overlords of the cell, mitochondria, videoed through a microscope. Yeah, I know. Not as many bean-like shapes as you were expecting? Your textbooks lied to you.
#Science
#Biology
#CellBiology
#Art