Science. Anaesthetist & Intensivist. Life always a choice between hospitals&saving chimps in the Congo. Once slept in a museum. Mitochondria & Asgardarcheota
Fascinating. The most detailed 3D rendering of a eukaryotic cell by
@CellSignal
and
@gmcgill
modeled using X-ray, nuclear magnetic resonance (NMR), and cryo-electron microscopy datasets.
More here:
Covid intensive care is: hourly arterial blood samples to check oxygen levels, lines placed into arteries to sample them, lines in the jugular vein to replace electrolytes we have driven out of the body by trying to flush excess water from the lungs, lines into the neck and groin
Surge in (young) Covid admissions. Nearly all unvaccinated. All not fully vaccinated (as in, one jab). Consequences of Covid requiring hospital in 20-30 year olds is 30% chronic organ damage affecting lives one year later. By all means weigh up risks, but Covid is not a cold.
I cancelled our wedding twice for covid. In the end ran away with just our parents and siblings, did my own hair and make up. Was kind of perfect actually!
But it isn't really our dream hospital right now. Vigilante style videos of empty outpatients don't really do this reality justice. Death figures, don't do survival reality, justice.
Something I truly cannot get my head around tonight is how all these consultant paediatricians went to their medical director, suspecting child murder, the royal college of paediatricians advised external death reviews, an external review said four deaths categorically needed
I've seen everyone from early thirties through to nineties, dying. The above is the story of icu survival, some never make it. Of course this represents a minority of covid patients, but it is bleak. Medics don't have a political agenda to oppress the masses.
To attach people to artificial kidneys - blood is pumped out of the body, round a circuit, and back inside, after being filtered of toxins. It is being away from home for at least a week or two or six, never able to get your breath, only able to oxygenate with a pressure mask
Got absolutely soggy, abandoned all of last year's wedding plans, had to do our own hair and make up, and clamber in rock pools barefoot (for the art...) but made it official today!
Leaving you breathless when it's taken off to eat and drink. It's being run from the ward to icu for an emergency intubation, to be put into a coma. To have a plastic tube inserted into your mouth and down windpipe, so a machine can breathe for you.
Hourly thick wet secretions, often green or blood stained have to be suctioned out of the lungs. Every so often the strain on the lungs is too much and one ruptures, needing a chest drain inserted between ribs into the thoracic cavity. Sometimes both lungs.
Forensic investigation, and yet despite receiving all this info, that medical director told the board specifically no reason to think any deaths were unnatural?!
And still has a leadership position job to this day?
The consultants ended up referring themselves to police? WHAT
It's blood transfusion after blood transfusion as the bone marrow starts to fail, and anaemia sets in. It's being turned on your front over and over to get the oxygen levels up - teams of five people to turn an intubated patient in a coma.
It's thinking you are imprisoned, trapped, or in hell, fluctuating between orientated and delusional. It's setbacks - another bleed, another infection. After weeks of steroids and coma, almost complete full body paralysis, barely able to move fingers, due to muscle weakness.
It's endless rounds of phoning micro to ask advice on yet another infection - sometimes fungal, maybe secondary viral such as CMV. Routinely a line infection or secondary bacterial pneumonia. It's starting on clarithromycin through to tazocin , meropenem, linezolid and the
Whilst poorly, having constant head turns 3-4hourly to avoid brachial plexus/muscle injury and head sores. Having people constantly check and lubricate your eyes so there is no damage to the eye whilst on your front - people have gone blind.
Last frontier tigacycline - cultures coming back more and more resistant as time goes on. It's being unwell and developing bleeding in the gut, requiring cameras down the throat and adrenaline injected into ulcers to stop them bleeding.
Awake, still unable to talk to loved ones on facetime as the trache is needed. It's having all those lines replaced, as they get infected or clotted up, every week roughly. It's having nightmares and seeing demons and the death of loved ones, in vivid hallucinations.
Just told a small child I was Elsa from frozen to freeze their hand with cold spray and put a drip in. This worked so well I must advocate the immediate purchase of an anaesthetic department blonde wig
When it comes to weaning and waking, it's having a trache put into the neck and trachea, temporarily taking away any ability to speak. After weeks of sedation and coma, it's waking, far away from friends or family, in a room full of people in PPE.
It's being fed down a rubber tube through your nose into your stomach. It's diarrhoea, collected in a faecal version of a catheter. It's being catheterised so people can analyse and assess your hour by hour urine production.
Every so often I see people reassured when actively bleeding patients have a systolic BP of 100. To get a ballpark multiply their MAP by 80 and then divide that by 2000 (a squeezed shut systemic vascular resistance in stupid units - dynes.sec/cm5)
CRP - what I wish I’d been taught! This (large!) protein comes as a pentamer of units 23 k-daltons. It has equivalents in almost all species and is found on chromosome 1. It’s the arch enemy of bacteria ESPECIALLY encapsulated bacteria
I can see the bridge of my nose disintegrating over time...is there any way to reduce this/help the skin heal between shifts? So I sleep with Manuka honey on my face? Silver colloid? Unicorn hair? Vaseline?
@zoeharcombe
Anaesthetist here. All my patients at the moment wear masks while hospital stay and before intubation. I can assure you their sats are fine measured with hospital grade oximetry. Me and the surgeons fine too thanks. Fake news. Also sats more like 75% w covid so...wear a mask!
I would like to take a moment to discuss, fairly, the AstraZeneca clot news tornado. Firstly, it is safe. Venous thromboembolism has a background rate in population of 120 in 100,000 (0.12%) age 50, 50 in 100,000 age 25. Pregnancy 60 in 100,000.
Dr Brearey says he challenged her about whether she was making this decision against the wishes of seven consultant paediatricians - and asked if she would take responsibility for anything that might happen to other babies the next day. He says Ms Rees replied "yes".
can we get people who don't take vaccines because 'my body my choice' explain to the cancer patients why they might have their operation delayed, when vast majority itu beds taken up by unvaccinated people with covid. People are removed from the misery they cause
Has anyone ever accidentally met someone off twitter in real life? I once ran into an ED nurse who asked if was Jo from twitter and I had a total embarrassed meltdown and ran back to theatres
People who benefit most from our own vaccination status, after ourselves, are those we spend the most time with - family and friends. Sick of hearing about whole families coming in, all unvaccinated. This is a mostly preventable disease!
Er no, we had chairs taken out of rest areas, only a number of people could sit there together, there was def no booze. All our parties got cancelled two years in a row, and we all finished work, showered, and went home wondering which patient would last the week.
"I don't think at any time he thought he was breaking the law... he thought just like many teachers and nurses who after a very long shift would go back to the staff room and have a quiet drink"
Tory MP Michael Fabricant urges Boris Johnson to apologise
Remembering the days I’d have an anaesthetised patient, with epidural, central line and arterial lime by this time, their magnesium added to their bag, and now it’s an achievement to reach the lounge with a belvita biscuit by 10am
Being a millennial doctor is amazing. We (in the UK) at least experienced a time of peace and prosperity. My peers are of every colour, sexuality, background and region. Through them I understand the worlds of my patients better.
Self imposed covid mute on twitter for while. Back again for two on call shifts in covid ICU tomorrow and anyone else telling me it's invented and only affects the elderly will earn the wrath of a thousand suns.
Our interventional radiology service has been decimated by brexit and can no longer provide 24/7 provision. Directly affects strokes, head injuries and bleeding patients. NHS relies on European talent. Really sad 😔
Keep seeing covid19 is not ARDS circulating so few quick points. ARDS is defined by strict criteria, it is a syndrome, or a triad if one will, of hypoxaemia (FiO2: PaO2 ratio), bilateral infiltrates that are not cardiac-induced, and occurs within a week.
Do you know what it was both adorable and vexing this morning the number of 80year olds parking up for the vaccines this morning at the hospital outpatients. I spent a good ten minutes helping them with the ticket machine and the excitement was rolling off them!
Ever since heard SHO put tachycardia down to anxiety in bleeding patient with/ NORMAL BP (110/60) I have worried we all sometimes forget the physiology. That patient had 2L bleed.
This is the **simplified** maths of the situation (if any of it’s wrong please correct me!)
#meded
Lump in throat watching the Thai Cave Rescue docu on Disney. Giving a paediatric anaesthetic with no airway equipment, underwater, in the dark, through tiny rock chasms, for hours, with constant threat of drowning yourself and child. X12
Well. After the extreme left list I now have a further 1000 unsuspecting victims to torture with mitochondria and cell biology so welcome, you poor people!
You mean 3000 of our 4000 beds are now Covid patients? Guys this is mad. Please stop any unnecessary trips and just hold strong for a fortnight, please! These are all of our emergency beds, we won't have any left for accidents!
Okay pretty appalled
@gmcuk
that response to overt white supremicist Twitter account wanting to report a doctor to you for advocating mask wearing (!) was to link the reporting page. You're meant to have just looked how ethnic minorities treated by GMC and impact of complaints?!
@AstonDMorgan
I can't film it and wouldn't want to but I can write! I certainly don't feel anything special - we have excellent training and the nurses do so much of the bedside vigil, and those in ED/medicine wards have more patients than they know what to do with, but team sport!
Until I wrote equations down I didn’t always get how abnormal it is to be a young person, bleeding, who is tachy with a reasonably “low normal” BP. After bleeding, if you are ^^HR to maintain BP, you have lost stroke volume and are compensating with vasoconstriction.
@JAMAPediatrics
This is really a very dangerous and poor thing to publish. Very poor adjustment for the obvious confounders like maternal autism, exposure to teaching hospitals near academic campuses, use of epidural in complex disorders. No potential mechanism. Increased diagnosis.
So if you wanted to lose a whole generation of doctors, you'd be the prime minister who commented on sport but not the protestors calling to hang nurses and doctors who just slogged it during a pandemic. The opposite of leadership
@BorisJohnson
. Who helped you?
So a patient asked today if we ever talk to patients who have been in a bay/witnessed another patient arrest.
Literally never thought about this!?! (Apart from covid ICU where really tried to keep separate dying/more well people) Must be horrifying!
The cases of
#bawagarba
and
#yeh
show us that in everything but words, the
#GMC
will find individuals responsible for gross systemic failings eg 1) being impaired by computer systems going down (no blood results) 2) carrying two bleeps 3) covering a sick colleague
My main concern with the pandemic, is that GCSE science doesn't seem to be working. Public health, intepretation of studies, statistics, and critical analysis, clearly needs to be made mandatory. -climbs up hill, plants flag, awaits death-
My issue with the suicide rate under GMC investigation is that if any doctor had the same complication or unexpected death rate there would be serious investigations and probably even criminal negligence charges. This is a known issue in the modern era and needs solving
Where was that thread on silly datixes. I got datixed once for eating rice in the break room of a ward where patient had gluten allergy. First of all rice doesn’t have gluten&secondly intolerance isn’t anaphylaxis and also I couldn’t see how it would reach their small intestine.
Woke up to this human eggling on my birthday!
He is a week old 😭 still got his little forceps/where he got stuck marks :(
Trope but I do find it amazing he’s here cos a little bacterium snuck inside a cell a billion years ago.
@ficrosbie63
@doctor_oxford
I think I sometimes forget how grim it is too, being the patient. For us it is another day at work (albeit the same constant tide of long stay patients, without the lift from the ones we usually have that get better fast and cheer you up). ICU is magic, but hard.
You know what is even extra unfair, working a 13 hour Xmas day shift and then only being allowed 3 hours with family Xmas bubble cos you’re not allowed to do it on 26th instead. Thanks for the constant shafting of frontline staff in this debacle in addition to Everyone else.
I really have a new appreciation for palliative care over the past year. They are really one of the most symptom based specialties. They look at eradicating symptoms, we others can get sidetracked by eradicating the disease.
AZ vaccine is now more convincingly linked to a rare type of clot that occurs in veins of the head. The absolute numbers v small indeed - 30 out of 18 million. The risks from Covid still far outweigh this risk of this clot in most age groups. Work ongoing to establish pathway.
Ventilation! So ventilation is positive pressure it blows air in (and oxygen) down into a cuffed airway tube which inflates the lung...and then releases the pressure to let the elastic recoil of the chest push air out again...sometimes you leave a little bit of pressure (PEEP)
@hazbeen1
I am so sorry :( hopefully whilst in deep coma people are aware of very little. They will always get chatted away to and called "love" and "sweetheart" a lot and gently washed, affectionately spoken to and have songs played on the radio too! Really am sorry. Xx
One of the deepest dives I’ve done in medicine is looking at metabolism of immune cells in sepsis. It is one of the areas that is clinically vastly ignored (despite years of academic work!) and needs translating (long thread 🧵 sorry!)
How were my nights?
What I took to work: sweet potato and houmous
What I actually ate: quavers, crunchie and Santa chocolates
Can we put all the on call teams on statins pls
As usual, randomly been paid incorrectly for two random months. Haven't even moved hospital this time. Did we take a 40% pay cut or can you just not be bothered to look after your staff's interests? Why would anyone offer to do extra shifts when can't get basics right
@nickylabour4eva
@IHPower
That isn’t why people with certain conditions and frailties aren’t necessarily good candidates for ICU. If it was a value judgement we wouldn’t want to take criminals or wife beaters either! It’s done on an individual basis with respect to survival chances - which sadly affected
Saying all Gp appointments to be seen within two weeks is like saying all joint replacements must happen within the month - without a magical draft of unicorns and pixies it’s not actually feasible. Worst crisis in my career and that’s our leadership 😭
Being an anaesthetist, it makes me incredibly happy to have exactly 9300 followers because both 9 and 3 are divisible by 3 and they add up to 12 which is divisible by 3, its all divisible by 10, which gives 93, and 93 is divisible by 3 giving 31, making it a Blum integer
To put it further in perspective we had results at our intensive care conference that 50% staff have PTSD (!) and 15% have been suicidal.
Our “leaders” partied and snogged their mistresses.
All good all good
What is an mRNA vaccine? One that instructs the human host cell to make isolated viral proteins (not the whole virus just a surface protein!) so the immune system learns about it and will be ready in future.
For the benefit of non medics who follow me, the reporting on Archie battersbee is poor and euphemistic. He is not in a coma or fighting for his life. Even a month ago, his brain was decomposing and blood flow had not been seen to it for over four weeks. He is brain dead
We lost my cousin, in his late thirties, today. To addiction. I wish there was a cure for this terrible chronic disease with this hideous prognosis and little quality of life. Remembering the little boy I grew up with, kind and active.
Uncharacteristically took a smoothie to work for breakfast, beetroot and apple, tripped on curb, spilt all over myself, adorable passer by thought I'd been stabbed and offered to call police.
@RichardCleal
@BBCNews
because I'm not letting anyone film the identities of my dying patients when not even their family is allowed to come in and sit with them. Patient doctor confidentiality?!
Did anyone else ever wonder why the Black Death bacteria was so effective? It has cousins that don’t really do anything exciting. Yersinia pestis has 3 key virulence factors.
why is it when you are a UK medic, you look like you are on the run from the police, given a change of address every 12 months like clockwork. I have had 11 addresses in 12 years and I can't stand these forms.