Jack O'Meara @Jack_O_Meara Twitter profile

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Jack O'Meara

@Jack_O_Meara

1 year

Liver Utd.

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Last Seen Profiles

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Jack O'Meara

@Jack_O_Meara

2 years

So proud of our team! And excited about this next phase as we prepare new medicines to actually improve patient lives. Nuts to be featured in the @FinancialTimes . I used to stack the FT every Sunday morning at work growing up in Ireland.

Oxford biotech raises funds to make RNA treatments for liver disease

Ochre to test drugs in hundreds of donated human organs kept alive in labs

www.ft.com

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Jack O'Meara

@Jack_O_Meara

1 year

I am one month from turning 30… By the skin of my teeth! Feel grateful to work in a field where our end game is to leave the world a healthier place, and to do so surrounded by such talented and passionate people is a blessing. Thank you #ForbesUnder30 ! #blushing

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Jack O'Meara

@Jack_O_Meara

3 years

“It’s a feckin’ long way from 10 Downing St you were reared, gossun” - my darling mother.

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Jack O'Meara

@Jack_O_Meara

2 years

We just manufactured our first batch of in-house RNA medicine ❤️ In the words of Dr @LocRoux1 : “Look at this beautiful powder!!!”

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Jack O'Meara

@Jack_O_Meara

2 years

Just ran after a candidate after a job interview and made them an offer in the car park. Felt like a dramatic scene from a romcom. We are going to have the best People & Culture function if they accept 🤞

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Jack O'Meara

@Jack_O_Meara

3 years

Finally got to meet the wonderful Nabiha Saklayen in person!!!! ❤️‍🔥 (after a year of burning her ear off every Sunday) @nabsicle

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Jack O'Meara

@Jack_O_Meara

2 years

After 3 years here, UK biotech is finally starting to feel like Boston/SF. Met @drrichjlaw at Exscientia for coffee, bumped into @rosdeegan of OMass Tx over lunch, and had dinner with @nathanbenaich and a group of founders/academics/policy advisors. A “cluster” is blossoming!

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Jack O'Meara

@Jack_O_Meara

9 months

Is there a “SAFE note” for biopharma partnerships? To avoid months and months of negotiating every minutia future outcome. If we could just get started faster, we know good stuff will happen… Credit: #longwoodhealthcareleaders Cc: @snowmaker @ycombinator @LongwoodFund

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Jack O'Meara

@Jack_O_Meara

2 years

As an update: THEY ACCEPTED!!! The digital romcom is now complete

Jack O'Meara

@Jack_O_Meara

2 years

Just ran after a candidate after a job interview and made them an offer in the car park. Felt like a dramatic scene from a romcom. We are going to have the best People & Culture function if they accept 🤞

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Jack O'Meara

@Jack_O_Meara

2 years

A happy scientist in New York

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Jack O'Meara

@Jack_O_Meara

2 years

For all you folks interested in biotech VC. Michael Retchin strikes again with great insights. V glad people are taking time to help illuminate their paths for those coming behind.

Michael Retchin

@MichaelRetchin

2 years

Want to break into biotech venture capital? Here are 10 fellowships with upcoming applications. Learn tech landscaping, sourcing, due diligence, and company creation. (Plus 14 more at the end.) THREAD🧵

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Jack O'Meara

@Jack_O_Meara

3 years

Very proud of the progress we’re making to tackle chronic liver disease here in Oxford. Thanks to Brian Gormley ⁦ @WSJVC ⁩ for covering ⁦ @OchreBio ⁩ today. With great investors onboard, we’re now on a path to bringing medicines to patients.

Biotech Startup Ochre Bio Lands Seed Financing to Combat Liver Diseases

Biotechnology startup Ochre Bio has raised a $9.6 million seed financing led by Khosla Ventures.

www.wsj.com

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Jack O'Meara

@Jack_O_Meara

2 years

Mini-IPO (Initial Pub Offering) / biotech meetup happening tonight at McSorleys in NYC w @MichaelRetchin @singareddynm @pablolubroth at 6:30PM. Come if local/free!

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Jack O'Meara

@Jack_O_Meara

1 year

Is anyone using ChatGPT for analysing genomic data / discovery? We have terabytes of single-cell, spatial-seq & histology data, mapped to clinical variables, on thousands of liver samples from UK to Taiwan to NY. I wonder what targets ChatGPT might prioritize for testing 🤔

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Jack O'Meara

@Jack_O_Meara

3 years

This week, a brand name bio fund turned down a first meeting* citing “we don’t recognize the team” as a reason. (??!). That, in a nutshell, is why I expect “tourist investors” to get returns. More than any sexy new tech in drug disc. *w/ warm intro by respected bio exec

Jake Becraft

@DrSynbio

3 years

Myself, and any other biotech CEOs in Boston under 40 years old, have no shortage of stories of being condescended to due to nothing but their age. This is changing due to an increase in outside capital, and is leading to huge breakthrough successes like @Ginkgo

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Jack O'Meara

@Jack_O_Meara

1 year

Bringing first-in-class targets to market first beats a best-in-class therapeutic modality, per @BCG ’s recent analysis of the last decade of biopharma product launches. We don’t need more fast followers. We need new target biology.

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Jack O'Meara

@Jack_O_Meara

10 months

Very honest discussion on the rise and fall of Triplet Therapeutics, covering real detail from IP to pre/clinical planning. Recommended listening for those endeavoring to develop new medicines.

Episode 32: The Triplet Therapeutics story, from concept to birth, life & death.

Listen to this episode from Between the Biotech Waves on Spotify. Today we have an unusual (& long) podcast where we talk to key members of the Triplet Therapeutics management team. Triplet was...

open.spotify.com

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Jack O'Meara

@Jack_O_Meara

2 years

In NYC? Enjoy free beer, bites, and biotech? Come for a discussion on how to make NYC the new Boston.

Michael Retchin

@MichaelRetchin

2 years

How can we build a strong community for life sciences innovators? I think about this constantly. If you do, too, join me March 21! Panel & biotech meetup with @NucleateHQ @OchreBio @GaingelsVC . So excited to moderate! RSVP below👇

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Jack O'Meara

@Jack_O_Meara

1 year

This book is a beautiful depiction of the creative process to build something out of nothing, as well as the relationship dynamics and personalities therein. While nothing to do with biotech, it still feels sort of familiar in a way. And it’s just an absolutely gorgeous read.

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Jack O'Meara

@Jack_O_Meara

9 months

Wrapped up a 9-hour science strategy board meeting [/marathon] in NYC. Liver disease, we’re coming for you!

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Jack O'Meara

@Jack_O_Meara

11 months

Interesting slide from recent @Stifel report: 2022+: Move from rare to chronic disease. Polyindication targets. Aging medicine matures. 2036+: AI + biology. Life expectancy up a lot. “Not clear that a traditional big pharma wins here. May be a company from Silicon Valley.”

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Jack O'Meara

@Jack_O_Meara

1 year

#BIO2023

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Jack O'Meara

@Jack_O_Meara

3 years

🤘

Ochre Bio raises $9.6m to advance RNA therapies for liver diseases

Biotech Ochre Bio has raised $9.6 million in a funding round to help it advance the development of its RNA therapies.

pharmaceuticalmanufacturer.media

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Jack O'Meara

@Jack_O_Meara

1 year

Welcome to Boston. Where turkeys cross the road. #BIO2023

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Jack O'Meara

@Jack_O_Meara

10 months

What makes the incumbents in this sector so enduring? Hovering at $250-500B market cap. What would a challenger biopharma with $1T+ potential look like?

Elad Gil

@eladgil

10 months

Top 5 biopharma companies all but 1 started in the 1800s or earlier 🤯

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Jack O'Meara

@Jack_O_Meara

2 years

Not one company working on improving human health. Like wtf?

Steve Jurvetson

@FutureJurvetson

2 years

Q4 Ranking of the most sought after private companies. Much fintech & crypto. Only two companies — SpaceX and Impossible — make things. "SpaceX is officially crowned the #1 most sought-after company of 2021 and Stripe #2 as they held these top spots over the last four quarters"

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Jack O'Meara

@Jack_O_Meara

1 year

35-45% of new drugs that make it into the clinic are not actually effective at treating human disease. Despite working in animals beforehand. We need better translational models to improve success rates for new medicines.

Gene Investing w/Anthony 🧬

@GeneInvesting

1 year

➡️ Analyses of clinical trial data from ‘10-‘17 show 4 main reasons attributed to the 90% clinical failures of drug development: lack of clinical efficacy (40%–50%), unmanageable tox (30%), poor drug-like properties (10%–15%), lack of commercial needs, poor strategic plan (10%)

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Jack O'Meara

@Jack_O_Meara

1 year

Found this photo from ~1920s, of my great grandfather founding a potato trading business. Is there an entrepreneurship gene? And can it be silenced with RNAi?! 😂

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Jack O'Meara

@Jack_O_Meara

1 year

ChatGPT making our corporate strategy sound sexier than I ever could

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Jack O'Meara

@Jack_O_Meara

1 year

Accurate for most ai drug discovery cos with low quality data. Even pharma.

Nikhil Krishnan

@nikillinit

1 year

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Jack O'Meara

@Jack_O_Meara

6 months

Happy holidays from @OchreBio UK 🎄

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Jack O'Meara

@Jack_O_Meara

2 years

I am so grateful to YC & EF for their support, advice and friendship over the years

Y Combinator

@ycombinator

2 years

Congrats @Jack_O_Meara , @QuinWills , and team @OchreBio on the Series A! Using a combination of deep phenotyping, precision RNA medicine, and testing in live human donor livers, Ochre Bio (YC W20) is developing therapies for chronic liver disease:

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Jack O'Meara

@Jack_O_Meara

1 year

I look forward to working with @HSBC_UK and am sure I speak for the entire UK sector in saying THANK YOU to the civil service team who probably haven’t slept since Friday to make this happen. Not all hero’s wear capes.

Jack O'Meara

@Jack_O_Meara

1 year

Ochre would bank with an SVB acquirer.

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Jack O'Meara

@Jack_O_Meara

2 years

Festive freeze. Happy holidays from 🇮🇪 ☘️

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Jack O'Meara

@Jack_O_Meara

2 years

Hiked Ireland’s tallest mountain this weekend. This country is stupidly beautiful. Put it on your post-Covid travel list people!

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Jack O'Meara

@Jack_O_Meara

2 years

I was in London on St Paddy’s day and no one gave a shit. Now in New York two days later and they’re still celebrating Paddy’s day. God bless the USA.

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Jack O'Meara

@Jack_O_Meara

2 years

RNA-based therapeutics: an overview and prospectus

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Jack O'Meara

@Jack_O_Meara

9 months

“If that’s true, can the drug discovery process do most of the research in silico and leave the wet lab stuff to validation? That’s the thesis, as opposed to doing the search for the compound experimentally, which goes much slower.”

Exclusive: DeepMind’s Demis Hassabis unveils his vision for Isomorphic and AI’s future in biotech

While Demis Hassabis is best known for steering Alphabet's research efforts in artificial intelligence, the 47-year-old is simultaneously leading a secretive biotech startup looking to bring about an...

endpts.com

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Jack O'Meara

@Jack_O_Meara

7 months

We turned 4! Cake for all

Ochre Bio

@OchreBio

7 months

Last week Prof. @noraio1 shared his wisdom on data-driven R&D decisions in #biopharma , culture, and the need to conduct regular audits of your decision making processes. To top it all off, we also had cake to celebrate our 4th anniversary! 🎂

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Jack O'Meara

@Jack_O_Meara

2 years

Sometimes I really question why I don’t live in the west of Ireland.

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Jack O'Meara

@Jack_O_Meara

2 years

Feels like style and design has traditionally been an afterthought in biotech (understandable given we’re making drugs prescribed by doctors), but perhaps that changes in an era of talent wars and new technologies. Art, science, and entrepreneurship are each rooted in creation.

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Jack O'Meara

@Jack_O_Meara

2 years

“Before the entrance of techbio VCs, there was virtually no way to raise initial capital for a biotech startup unless you were part of, or close with, one of the main VCs.”

The next generation of biotech VCs

Traditional biotech VCs are being overtaken by emerging funds.

www.baybridgebio.com

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Jack O'Meara

@Jack_O_Meara

1 year

Everytime I talk to a young person about their career aspirations, they almost always tell me they want to either work in climate or health. That amount of intellectual energy has got to make the next decade incredibly promising.

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Jack O'Meara

@Jack_O_Meara

2 years

The @OchreBio team smashed the ‘Town and Gown 10km’ run this weekend for Helen and Douglas House, who provide hospice care to terminally ill children in Oxford. If you would like to make a donation here's the link: 🙌

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Jack O'Meara

@Jack_O_Meara

8 months

Proud to be a co-host. Tony was very kind to @OchreBio in our early days in 2019. Hope I can pay it forward, sharing some of what I’ve learned to lift up next generation of scientific entrepreneurs and advance the innovation ecosystem.

Tony Kulesa

@kulesatony

8 months

📢 The 2023 Founder-led Biotech Tour In November, we're teaming up with 50+ founders to bring the community together in four cities. SF: 11/2 Boston: 11/7 NYC: 11/9 London: 11/13 + virtual events including co-founder matching, speed networking, and more.

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Jack O'Meara

@Jack_O_Meara

3 years

Continue to be blown away by the quality of the content on a weekly basis by @cngarabedian , @bradloncar & @daphnezohar . For anyone in biotech, highly recommend this Sunday routine.

Chris Garabedian

@cngarabedian

3 years

REMINDER 🧬 @BiotechCH “Biotech Clubhouse: Sunday Hangout” w/ me, @bradloncar , & @daphnezohar Join us tomorrow Sun June 27 at 4pm EDT w/ special guest @UrnovFyodor to talk about gene editing and latest @intelliatweets data!

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Jack O'Meara

@Jack_O_Meara

10 months

Another good podcast: Medicine needs to get faster & more targeted. 3 years from target to small molecule is just too long. Organ specificity is key. Eventually capital markets reward the “supply & demand” gap between new biology & our modality toolkit.

Drugging the Undruggable with Greg Verdine

Listen to this episode from Raising Health on Spotify. When Greg started out in science, he heard other researchers referring to certain targets as “undruggable.” In response, he’s devoted his life...

open.spotify.com

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Jack O'Meara

@Jack_O_Meara

1 year

Smart people join Ochre. 💪

Ochre Bio Strengthens Leadership Team and Board of Directors with Liver Disease Translational...

Ochre Bio, an innovator in chronic liver disease medicine development, is pleased to announce the appointment of David Coughlan, PhD as VP of Translational Development and Chinwe Ukomadu, MD, PhD as...

www.biospace.com

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Jack O'Meara

@Jack_O_Meara

2 years

Incredible time to be in medicine. Imagine a vaccine for acne (for teenagers)? I mean that’s pretty cool. If someone cracks cell specific delivery of mRNA, possibilities really are wild.

Fierce JPM Week: After 'objectively astonishing' progress on mRNA, biotech looks to tinker with...

Messenger RNA (mRNA) technology became a household name so quickly thanks to the COVID-19 vaccines by Pfizer-BioNTech and Moderna, and, now, biotech leaders are taking a | Messenger RNA, or mRNA,...

www.fiercebiotech.com

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Jack O'Meara

@Jack_O_Meara

1 year

Oxford Science Park’s Innovative Award…. Runners up. So close! @OchreBio #OneTeamOneDream

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Jack O'Meara

@Jack_O_Meara

1 year

Thanks to the @FT for featuring us. Pulling R&D rebates for early stage cos, at a time of unforgiving capital markets, acute inflationary pressures, and when UK biotech is finally blossoming — is, quite frankly, daft. @RishiSunak @Jeremy_Hunt

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Jack O'Meara

@Jack_O_Meara

2 years

@SaraNayeem I keep a list of all of these *excellent* threads. THANK YOU for what you are doing to share knowledge across biotech community!

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Jack O'Meara

@Jack_O_Meara

2 years

“The 5-year average sits at 51 drugs per year. A decade ago, it was 24 drugs per year.” Wow.

2021 FDA approvals

Nature Reviews Drug Discovery - The FDA approved 50 novel drugs in 2021, including the first KRAS inhibitor for cancer and the first anti-amyloid antibody for Alzheimer’s disease.

www.nature.com

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Jack O'Meara

@Jack_O_Meara

8 months

We applied 2 months after the deadline and interviewed 2 hours before the start of the actual batch. Changed our trajectory significantly. Would highly recommend applying.

Y Combinator

@ycombinator

8 months

p.s. you can still apply to YC after the regular deadline

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Jack O'Meara

@Jack_O_Meara

3 years

Excited to be a part of this new founder-led movement in biotech. The more energy & creativity that goes into the field, the more breakthroughs for human health we are likely to see.

Tony Kulesa

@kulesatony

3 years

Fri 4pm ET / 1pm PT, join us to learn how next generation 'omics technologies are impacting biotech. Inspiring group @MarianaMatusG , @Jack_O_Meara , and @mpcadosch . Congrats to @BiobotAnalytics just announced their $20M Series A, read more:

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Jack O'Meara

@Jack_O_Meara

2 years

Really enjoyed talking to @ky_lahucik of @endpts about the ways early stage founders support (and club with, lol) each other. I am beyond grateful to all of my peer mentors & support networks. From the tactical to the emotional variety. It takes a village in biotech…

Kyle LaHucik

@ky_lahucik

2 years

my 1st @endpts feature, about biotech founders tweeting, texting & clubbing (of the Clubhouse variety) I spoke w/1st-time CEOs @lexrovner , @Jack_O_Meara & @DrSynbio w/some 'scared sh*tless' serial entrepreneur perspective from @michael_gilman :

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Jack O'Meara

@Jack_O_Meara

9 months

I ❤️ NYC

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Jack O'Meara

@Jack_O_Meara

1 year

The UK government said they wanted to make the UK a life science superpower. Well, it looks like they mean business. This is great news for small companies like @OchreBio .

HM Treasury

@hmtreasury

1 year

We're introducing additional tax support to help research & development intensive SMEs. For every £100 spent on R&D, eligible companies will be able to claim £27 back, helping them to invest in more R&D and grow for the future.

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Jack O'Meara

@Jack_O_Meara

3 years

We upsized the venue as the 40 person space was oversubscribed in <24 hours 😬. After two years of lockdown, I think we all need a drink... Come for a 3D beer in Boston on Dec 1st: @DrSynbio @nabsicle @dj_mandell @kulesatony @AaronPMorris

CANCELLED - Founders and Friends: Winter Biotech Happy Hour

CANCELLED

www.eventbrite.com

Jack O'Meara

@Jack_O_Meara

3 years

For anyone in Boston on Dec 1st. Let's get drinks in 3D! @DrSynbio @nabsicle @dj_mandell @AaronPMorris

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Jack O'Meara

@Jack_O_Meara

3 years

Will be discussing “Building Biotech w/ @TheDawnBell , Global Head of Strategic Partnerships @ Novartis” and @nabsicle , on @dnatieclub . Tomorrow, Dec 12 at 6:00 PM GMT on @clubhouse . Really excited for this one. Dawn is a rockstar. Join us!

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Jack O'Meara

@Jack_O_Meara

2 years

Spreading the good word of @OchreBio . Wow, tech conferences are cray cray.

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Jack O'Meara

@Jack_O_Meara

2 years

A seasoned biotech founder just told me that years ago a reputable fund passed on him saying “lightning rarely strikes twice; we think you’re unlikely to have an exit as successful as your first one”. How hilarious is that in the context of todays market for first time founders

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Jack O'Meara

@Jack_O_Meara

3 years

Regretfully, today’s @dnatieclub Building Biotech session is cancelled. Back next week with Sean McClain, who founded @abscibio at 22 in 2011, and just rang the NASDAQ closing bell as CEO. Wow. What a journey & eg of founder-led biotech. @NucleateHQ will join too; Sundays 6PM UK

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Jack O'Meara

@Jack_O_Meara

1 year

Lovely initiative to volunteer at a food shelter during JPM chaos. Healthy reminder of the context within which the conference exists. Please excuse the dodgy dance moves

sarah monier-Williams

@monier_williams

1 year

@Jack_O_Meara @Jack_O_Meara at #JPM23 rocking the @ProjectOpenHand @ideapharma volunteering and making a great contribution (less the odd pinto bean) to the 2,500 daily food parcels

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Jack O'Meara

@Jack_O_Meara

1 year

From day one, we have been developing a repository of highly curated genomic data, across three continents. Algorithms will be commoditised. Modalities will be commoditised. Differentiated products will create value for society.

Science Is Strategic

@scienceisstrat1

1 year

Great clip from @chamath describing who the ultimate financial winners may be from the generative AI revolution

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Jack O'Meara

@Jack_O_Meara

3 years

Now this is a real EU/UK success story. Biotech, deeptech, frontier tech. Whatever you want to call it. Here’s hoping it unlocks a lot more capital on this side of the pond, bringing with it a lot more innovation and science to improve human health. Bravo @exscientiaAI team. 🙌

Nathan Benaich

@nathanbenaich

3 years

🎉A few hours ago, @exscientiaAI became a $3B+ NASDAQ-listed public company and a first IPO for @airstreet . This is day 1 for a category-defining AI-first drug discovery company that is now the 3rd largest biopharma company in the U.K. next to @GSK @AstraZeneca . Let’s go!

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Jack O'Meara

@Jack_O_Meara

2 years

This. This. This. I’m convinced we are going to see this exact same trend in biotech, just five years behind tech (as usual).

Paul Murphy

@paulbz

2 years

European venture investment was $113b in 2021, up 135% from 2020, similar to US in 2019. European IPO's raised $105b in 2021, up 780% from 2020, nearly double what US raised in 2019. We predicted EU will be on par with US in coming decade but we are *much* closer than thought.

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Jack O'Meara

@Jack_O_Meara

3 years

Month = made

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Jack O'Meara

@Jack_O_Meara

3 years

Just got a very polite lecture on how not to get my bike robbed. From someone I caught trying to rob my bike. Oh, London.

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Jack O'Meara

@Jack_O_Meara

11 months

Same in biotech. Large influx of ambitious talent as tech loses appeal [why optimize back office SaaS when you can work on life saving medicines?!] Challenge is the industry is less amenable to naïveté, but will be impacted nonetheless

Vinod Khosla

@vkhosla

11 months

The field of AI was puttering around incrementally. I knew it would explode because that's where all the best minds were going. Some will say it was the transformer paper and computing at scale that catalyzed this moment. For me, it was about following the talent and the

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Jack O'Meara

@Jack_O_Meara

2 years

Found my first (and second) grey hair today. Tear. The downsides of starting companies: premature greying.

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Jack O'Meara

@Jack_O_Meara

3 years

Just got our 2020 R&D tax credits (read: cash injection) from the UK govt. ~25% of annual spend. Great for biotechs extending runway to hit value inflections and another reason to invest in UK biotech/deeptech/R&D businesses.

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Jack O'Meara

@Jack_O_Meara

2 years

Flying to NYC (yay) for two weeks w work 🍎. If anyone is in town and wants to grab coffee, hmu. Also partial to a beer…

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Jack O'Meara

@Jack_O_Meara

3 years

Got a cycling desk. I think I’m in love.

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Jack O'Meara

@Jack_O_Meara

8 months

“We’ve also now realized if we want to change the probability of success in the clinic, it’s not just better molecules,” Hopkins said. “We also need better translational models.” Correct.

Andrew Dunn

@AndrewE_Dunn

8 months

NEW: The first 3 AI-designed drugs got lots of fanfare when they entered the clinic — not so much when they quietly fell out. I talked with the AI field about what an 0-for-3 start in human testing means, and whats' next for the field:

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Jack O'Meara

@Jack_O_Meara

3 years

Very proud of my inspiring cofounder, Quin Wills, for what he is doing for LGBTQ+ in biotech❤️ “At the end of the day, in my mind, there is nothing more powerful than folks seeing leaders who look like them, who talk like them and who love like them”

'Day job and a gay job': LGBTQ+ leaders in biopharma want those who look, talk and love like them...

Editor's note: This is the final piece in a three-part series profiling LGBTQ+ leaders and inclusion ef | Organizations for LGBTQ+ biopharma employees are popping up in Boston, San Francisco, New...

www.fiercebiotech.com

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Jack O'Meara

@Jack_O_Meara

2 years

Great talk. And then, where all the good ideas flourish: the pub.

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Jack O'Meara

@Jack_O_Meara

3 years

Just got pitched to send some of our in vitro assays to space. Actually not bad pricewise compared to other CROs (which says a lot about CRO pricing). If only there were any scientific rationale for doing so…at all…

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Jack O'Meara

@Jack_O_Meara

7 months

Shameless plug. Interesting new podcast series mixing science and finance in narrative format; Surani does a great job.

S1, E2: Ochre Bio with CEO/Co-founder Jack O'Meara and liver expert Dr Scott Friedman, Mount Sinai

Listen to this episode from Raising Biotech on Spotify. In this episode of Raising Biotech, Surani speaks with CEO and co-founder Jack O'Meara of Ochre Bio, a company dedicated to tackling the large...

open.spotify.com

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Jack O'Meara

@Jack_O_Meara

9 months

Randomly met an artist who made this for a play. Naturally begged her to have if afterwards for our next office party.

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Jack O'Meara

@Jack_O_Meara

3 years

The weekly Building Biotech show broke the 300 mark for the first time yesterday 😳. It’s been a fun lockdown habit, and I’m grateful to have been able to chat with so many inspiring founders. And to have such an amazing cohost, @nabsicle ! Come join: Sunday’s at 6PM UK 🤘

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Jack O'Meara

@Jack_O_Meara

1 year

Only in london do they feel the need to advertise how waterproof their bags are

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Jack O'Meara

@Jack_O_Meara

3 years

For anyone in Boston on Dec 1st. Let's get drinks in 3D! @DrSynbio @nabsicle @dj_mandell @AaronPMorris

CANCELLED - Founders and Friends: Winter Biotech Happy Hour

CANCELLED

www.eventbrite.com

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Jack O'Meara

@Jack_O_Meara

1 year

AI in drug discovery panel @SynconaLtd When the sun shines, London is 🌞

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Jack O'Meara

@Jack_O_Meara

2 years

Excellent report. And @OchreBio gets a shoutout in the comp bio deep dive section (slide 26) 💪 This week has been crazy for pharma<>comp bio deals (Absci, Exscientia, Generate, etc). It’s exciting to see industry heavyweights lean into these technologies to find new medicines.

Chris Garabedian

@cngarabedian

2 years

One of the best @SVB_Financial @jonnysvb reports to date w/ more detailed sector, subsector and theme investor rankings than ever before!

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Jack O'Meara

@Jack_O_Meara

11 months

Still trying to not die.

Jared Friedman

@snowmaker

11 months

Most first-time founders are hilariously incompetent for the first couple of years (I certainly was). The ones that make it just manage to not die for long enough to get good.

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Jack O'Meara

@Jack_O_Meara

7 months

Very excited by latest Verve data and it’s potential to impact medicine, but this has been a question niggling at me through the whole CRISPR wave. Why CRISPR a common disease when safe, effective and long-acting (convenient) approaches already exist?

David Grainger

@sciencescanner

7 months

But still not as well (or certainly no better) than a six-monthly injection of inclisiran So the question I still havent got my head round is WHY? Minor convenience seems a very poor reason for altering your genome and accepting even a theoretical risk of off-target edits

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Jack O'Meara

@Jack_O_Meara

11 months

Dinner in SF with a friend from YC: “Wow, you haven’t gotten fat after 4 years CEO’ing. That’s an accomplishment in of itself.”

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Jack O'Meara

@Jack_O_Meara

3 years

Interesting report on UK biotech relative to EU and US. McKinsey’s final piece of advice to UK biotech sector: More mingling, lol. It’s true though. Here’s to more coffees, beers and serendipitous connections in the new year.

The UK biotech sector: The path to global leadership

The United Kingdom is Europe’s leading biotech hub in breakthrough life-sciences start-ups. How is this hub maturing relative to its global peers, and what lies ahead on the road to sustainable scale?

www.mckinsey.com

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Jack O'Meara

@Jack_O_Meara

6 months

I could listen to @JackScannell13 talk about predictive validity of translational models all day. One interesting hypothesis for pharma’s decline in R&D productivity is that all the good disease models have already been exhausted. The diseases that are left all have crap models.

BACKED 🏴

@BackedVC

6 months

On Tuesday we hosted highly oversubscribed 2nd edition of #LONDONBIO for over 50 of lifescience and techbio practitioners. We brought together some of the leading minds in European biotech, including frontier founders, academia, pharma and investors, in partnership w @OchreBio

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Jack O'Meara

@Jack_O_Meara

7 months

"A spokesperson for Flagship said the life sciences firm’s UK offices will officially open next week."

Flagship launches first UK-based startup to uncover genes that make cells vulnerable or resistant...

A new biotech startup believes that genetic diversity found among the trillions of cells that comprise an individual person could hold the keys to new clues for treating or preventing disease....

endpts.com

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Jack O'Meara

@Jack_O_Meara

2 years

Really looking forward to presenting at the @NYSE next week! Hmu if you’re in New York.

NewYorkBIO

@newyorkbio

2 years

The final 3 companies for our Emerging #lifescience Showcase Next week on Dec 14th at the @NYSE ! We can't wait! We're bringing together New York's #financial community and emerging companies developing #NovelTherapeutics in areas which could revolutionize #PatientCare

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Jack O'Meara

@Jack_O_Meara

1 year

"The UK is great at the ‘R’ and not so good at the ‘D’” "We need to think about how Genentech was successful. Basically one really successful scaled company can feed a whole ecosystem.”

The UK’s dream of becoming a ‘science superpower’

Ministers want to supercharge the £89bn life science industry. But it will take long-term thinking on investment, talent and infrastructure

www.ft.com

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Jack O'Meara

@Jack_O_Meara

2 years

Thanks to the wonderful Dr @LocRoux1 for showing @OchreBio ’s dry-lab, wet-lab, and no-lab teams around our new RNA chem-lab on @OxfordSciencePK 🧬

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Jack O'Meara

@Jack_O_Meara

3 years

Just went to a spin class in London where the lady shouted at me: “don’t let that bike ride YOU; live your f**king life!”. Lol. Sharing some saturday morning inspiration for you all.

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Jack O'Meara

@Jack_O_Meara

3 years

Finally got to meet our US colleague in person last week. To celebrate, we took him to one of Oxford’s beautiful old colleges for Pimm’s and scones (pronounced “sconns” apparently 🤔). How British. This photo is our only evidence (feat Quin mid-bite — which he’s delighted about)

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Jack O'Meara

@Jack_O_Meara

1 year

Happy holidays. From my house to yours.

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Jack O'Meara

@Jack_O_Meara

2 years

To the next generation of UK/EU biotech founders 💪

BioEscalator

@BioEscalator

2 years

Well done to @Jack_O_Meara , Co-Founder and CEO of @OchreBio and Jonathan Kwok, Co-Founder and CEO of Infinitopes for giving an inspirational talk to this year's SynBioUK Catalyse group on building biotech in the UK 🇬🇧🧪 Hosted by @SynBioUK & @join_ef

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Jack O'Meara

@Jack_O_Meara

3 years

Tomorrow, @nabsicle and I are chatting with @MarianaMatusG about building Biobot from 7 to 35 people remotely, while developing, validating & commercializing a C19 test in weeks rather than years. Biotech is moving faster than ever and Mariana’s story is a keen example.

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